ARCHIVE: Verapamil - Injections & Topical Applications including Iontophoresis

[Rico]

csup,

Waste of money and time, doesn't work, period, I know you said you had problems with pde5 inhibitors before, did you try cialis or levtira?.... pentox/cialias/arginine or ved, TV does not work....doctors will say that, the peyronies doctor don't prescribe it.... they will do injections, but tv doesn't get into the plaque...

Rico

[csup]

Rico,
You know, I get so confused trying to read thru all these hundreds of posts about this treatment, and that treatment, ...maybe that is why when I was in his office under his Dr. spell I succombed to the pressure. It is only going to cost me 60 bucks, and lately between the Peyronies Disease and my BPH, I have spent A LOT more on supplements. If it doesn't show any improvement in 90 days, then I can add my 2 cents to the negatives on this and feel comfortable doing it. Who knows, maybe I can will it to do some good using mind over matter. LOL. I also asked my Uro about p/a/v, and he said he had read the research and did not think it helped. I go back in 6 weeks, we will see what happens. crs

[Kimo]

CSUP,,,,I know that no one wants to hear this, but i did have positive results with the Topical Verapamil, i also used a natural vita-E 800iu a day....I know that no one wants to believe me,,but it worked for me...

I was twisted and bent like a donut to the left and in a lot of pain 24/7 for about 5 months before my doctoor prescribed the TV...I didn't see any results until about 10 weeks into the treatment, and at the end of 5 months i had regained back to about 85% straight, and now i am just slightly bent up...My plaque was the size of a quarter and thickness and very hard to...

I kept on using the vita-E for a couple of years or more < to long > ....I can't say it will work for you, but like i was told by my URO it's worth a try and i'm glad i did....

This is just my opinion and my experience, what you choose to do is up to you...I hope the best for you,,,,It's worth trying anything to get your unit back in shape, I don't downplay anything as what works for one person may not work for another....I think the VED is a good way to go also and some of the other things being suggested....

kimo

[csup]

Rico, Kimo,
Thanks for your supporting posts. They mean a great deal to me. Rico, I don't think you were trying to undermine my process, you have been involved w/ this much longer, and have seen more negative results. Kimo is one of the fortunate ones. Perhaps the TV will help me also. If it does not, I will have a very serious talk w/ my Uro about pentox, and if he still does not want to prescribe it, maybe I will find another Uro. The beat goes on. My prayers are with all of you. crs

[Steve]

Hi Csup,

For what it's worth, when I first went to my Uro, he also started off with TV.  His statement to me was something to the effect that he didn't think that the TV would do much, but he wanted to start off conservatively and work up to the more aggressive treatments.  I think that this is a common mode of treatment for most of the medical community (feel free to chime in here Dr Tim), and it makes sense to me.  If he'd suggested surgery at my first visit, I'm sure that I'd have been scared off!

[not9inches]

Can somebody tell me where to get  Topical Verapamil cream. do you need a prescription?

[Liam]

The book discussion was moved to "Urologist and Other Doctors".  This is only because the discussion was not related to the topic.

Thanks,
Liam

[Kimo]

Not9,,,,,,,Yes you need a prescription as far as i know, i needed one...Also, my insurance payed for mine, but my uro had to write a letter to the ins company 2 times stating that peyronies is a cause of ED,,,ie; one of the causes.....And back then i got my TV cream from PDlabs.......kimo

Can somebody tell me where to get  Topical Verapamil cream. do you need a prescription?

[Tim468]

>>I also asked my Uro about p/a/v, and he said he had read the research and did not think it helped. <<

If a doctor says he has read the reports on pentox and does not feel they work, then he didn't really read them IMHO (or he's dumb).

OTOH, if he said that he had read them and they are promising, but he is unsure if they will work as well in people as they have in rats, then he probably did read them and is being conservative. That's OK.

If he says let's go ahead and try it, he probably has the disease as well!

Tim

[ComeBacKid]

Tim is right, your doctor is clueless, just reading themself you can tell there is some promise.  The lab tests looked very promising, the human trials are under way, with one man supposedly "cured."  I encountered the same attitude from Dr. Mulhall in my last visit, he only acknowedged the lab testing part, not that one man had been cured, or significantly improved, obviously he did not read the same report I did, or he simply rejected it.  To me this was extremely frusterating, had I been on the ball enough to have a copy of that report I would of handed it to him and let him read it aloud.  Actually I was on the ball, I thought Dr. Mulhall would be so progressive with treating this disease he would of already known about Dr. Lue and everything there is to know about the pentox... I was wrong.

ComeBackid

[hopeful]

Thank you- I will consider this...

Hopeful,,yes i had a very positive result with the Topical Verapamil cream..I know that most people don't believe me but it did work for me...

[JAKE52]

DIFFERENT QUESTONS: Same intro as in another topic category. (So if you read this intro elsewhere, please skip to the new questions!)

I am brand new to this forum. First, my thanks to the sponsors and my fellow "victims" for sharing information, and thank you to all who read this long first posting and respond. I promise to be brief in the future with my questions and thorough with anything of value I have to share.

I am willing to DO ANYTHING that anyone has had even moderate success with and that had minimal risk for further harm. Thus I am posting this prologue in two subject areas since I am asking two separate questions at the end.

My situation is not much different from most I have read about here and countless other places on the web.  Even though I realize I will never have back my former penis, I am willing to try ANYTHING that ANYONE has had ANY degree of success with.  I have been to seven urologists from coast to coast to coast, six of whom promote themselves as Peyronies Disease specialists, even at major University research hospitals. And I have had no two recommend the same thing (except that MAYBE Colchicine and vitamin E MIGHT help, but there is no proof), other than the prognosis is not good and a return to original size and function will not happen.  Only one MD (the urologist with the fewest published credentials) urged swift and aggressive treatment (Verapamil AND Intron A injections PLUS Colchicine PLUS vacuum pumping) during the early stages when I just had a painful bend. All the "experts" urged me to wait six months, then another six months.  The waiting has been disastrous.  After one full year of steady high doses of Vitamin E and up to six tabs of Colchicine daily, my once proud 9.5x6 inch, naturally rock hard, stick straight member has been reduced to a Viagra-only reduced 3 - 4 inch hook  (i.e., slightly curve became a 45 degree dented hook) with the thick original shaft at the base, immediately tapering to finger size, and which is now only useful for "solitary" masturbation. I am single, and
humiliated to begin dating again. I am now resolute to take aggressive actions and seek forum members advice.  

Questions re: IntronA and Verapamil.  
1) Has anyone had both and can report on comparison?
2) I am very concerned about the risk of possible further injury by repeated injections into a sensitive area. Has anyone experienced further problems?
3) Is anyone unequivocally convinced injections after a year since injury has had any positive effect? (i.e., the improvement is not incidental or otherwise natural)
4) Has anyone had any success in getting medical insurance to cover either injection therapy? (United Healthcare refuses to pay for either the IntonA prescription or the costly injection procedures as it is not an FDA approved use of Intron. I know some plans have paid for the Verapamil injections.)
5) Since the course if therapy is at least 12 weeks, sometimes longer, I cannot find a published Peyronies Disease specialist local (South Florida) who will do the Verapamil injections (there is a noted urologist who will do IntronA only, which as I noted is not covered by my insurance, but will not do Verapamil as he insists it has proven to not be effective). I am concerned about just "any urologist" poking my penis with a needle who is not experienced and well trained in this procedure. is this an unnecessary fear/  Any suggestions? (I cannot afford to travel biweekly for six months across the country for treatmen

[Hawk]

Jake, Welcome to the PDS.  Your posts are an appreciated contibution to what makes the forum work.  

I would be concerned with any old urologist giving me Varapamil Injections VI.  I do not consider that an unnecessary fear.

We have a completed survey on our web site on VI that may interest you. http://www.peyroniessociety.org/survey_ilv2.htm

I will allow others to answer your other questions.

[ComeBacKid]

Jake,

Welcome to our forum.  You should take hawks advice and check out our own VI survey.  Also read my topical verapamil report, it is its own thread towards the bottom of the discussion forum.  Even the biggest promtoer of verapamil injections (Dr. Mulhall) states that they should only be done in the very beginning of the disease to prevent progression of the disease.  Personally, I would never have verapamil injections done, I have not heard from one person who told me they helped their case.  I can tell you 5 people have reported to me success in using the VED, I seem to be seeing results from it as well. I would read up on the ved thread and do some research using the search function. If you have any questions or need any help feel free to PM me anytime.

ComeBackid

[Tim468]

Hi Jake and welcome to the forum.

I am in the middle of a brutal morning of work, so cannot answer your queries. But I will try my best to think about it and to help give opinions (those are plentiful around here!) asap.

First off, I want to say how sorry I am that you are going through this. As much as I hate what has happened to my own dick, I feel so much for you and what you are going through. An enormous value of this forum for me has been finding a place to vent my frustrations and anger now and then, and to, by listening to others rant, find solace in the act of helping. It has helped me enormously in my 3D life in this regard and in being less ashamed or embarassed by this. Hang in there and we should see what we can do to help each other.

Tim

[hopeful]

Hi Jake... This is Hopeful, I read your post- and I feel as frustrated as you.  My condition- have had Peyronies Disease for 13 months now- 35% curve at tip- been to several docs-nothing as far as corrective. I have done a lot of research with enzymes- and was trying to find a topical enzyme rather than oral that would work- I found a company that is making one that has had good success with Duprens Disease again- however, I gave up as I expected immdiate results. I also did research for INOTOPHORESIS treatment from Physion- and yet to have found anyone on the forum that has had success.. I cannot get a list of Docs from Physion- which makes fgeel uneasy about buying the device! I believe in the modality, and I felt that a liquid enzyme would be great- cannot get an anwser.

I feel enzymes may be the key as soon discovered from the Forum, that Auxillium has a patented drug ( an enzyme) that has been succesful with Duprens? DIsease (Hand) and will begin testing on Peyronies Disease. However, the bad side of it- is how it is administered.. needle injection- My opinion- STUPID - as injections can cause additional scarring.. No need for this..

There is a company that I sourced INJEX www.injex.com, that just completed a 3,000 patient study, for delivering drugs to the penis via a needless injector ( Viagra, Cialis, etc) - for those patients who cannot take oral medication.  The success rate was incredible- I am waiting for the report.  I  trurned the company on to Peyronies Disease, and suggested that they contact some of the leading docs- and Auxillium to see if they would use the INJEX injector rather than a needle. I said I believe in Enzymes- and uf AUXILLIUM has one- this  sould be a perfect match!.

Also, I would like to know hold you are?- And the doc that wanted to do the INOTA injections, was that Dr. Hakim from Cleveland Clinic in Weston?- I live in South Florida as well.

Thanks,

Hopeful

 Only one MD (the urologist with the fewest published credentials) urged swift and aggressive treatment (Verapamil AND Intron A injections PLUS Colchicine PLUS vacuum pumping) during the early stages when I just had a painful bend. All the "experts" urged me to wait six months, then another six months.  

[hopeful]

Hi JAke.. Hopeful again, and to anyone else reading this thread.. I got this quote- from another web site- wriiten by Dr. Levine- basically confirms what I have been preaching!-

HOPEFUL

Lastly collagenases which are enzymes that the body makes to break down scar have also been used experimentally going back into the early 1980's as an intralesional injection therapy for Peyronie's disease. The rationale for use of this agent makes sense, which is to inject a drug that will enzymatically break down the plaque.[/b] Initial trials did demonstrate some improvement but studies were limited in terms of the number of patients, the number of injections and the means of reporting on improvement of deformity. The company manufacturing collagenase has had difficulty in getting support for their research studies to get FDA approval. Recently another firm has purchased the rights to this, and is pursuing a carefully designed multicenter placebo controlled trial. The hope is that with industry support, there will be a properly designed and well controlled trial which may not only show benefit with this drug, but the protocol could be used as a model for future new treatment options for Peyronie's disease.

[Steve]

  Not sure why this made the news, as I've seen these results at least a year ago...

Orlando, FL (PRWEB) November 28, 2006 -- Dr. George Carroll, specializing in the diagnosis and treatment of male sexual dysfunction for over fifteen years, is pleased to announce that preliminary studies using eletromotive drug administration (EMDA) have demonstrated encouraging results in the treatment of Peyronie's Disease. Dr. Carroll has found that the use of EMDA is especially effective in the treatment of the early stages of this pathology.

Basically, this is the Iontophoresis (although they're calling it EMDA) application of Verapamil and Dexamethasone.

Two of the very interesting quotes from the release:

Preliminary results being developed and documented by Dr. Carroll (www. treatpeyronies.com) using a panel of 24 patients treated in Dr. Carroll's office shows that:
o   42% of patients lost at least 50% of their curvature
o   53% lost at least 40% or more of their curvature
o   95% saw a decrease in curve ranging from a low of 13% decrease to a high of 100% decrease

and

According to Dr. Carroll "EMDA is the best initial option available today for the treatment of Peyronie Disease. Last year we began using a new EMDA / Verapamil/ SomaCorrrect protocol after published studies indicated that 76% of patients showed significant improvement with documented results. These are encouraging preliminary results, but we need larger numbers of patients and physicians willing to participate in further investigation."

:)I think that this is the first mention of Ionto with VED that I've come across in the literature.

Just thought I'd get some conversation started...

[Steve]

I visited Dr. Carroll's site (https://www.treatpeyronies.com) from the paper I included in my last post, and he's 'offering' the following:

*Mini-Physionizer 2.0
*SOMAcorrect device
* & All necessarry supplies for 25 Treatments
Price $1,785.00

He's also selling the EMDA device and the SomaCorrect indvidually (although the prices aren't any cheaper than you can find elsewhere).

One other interesting thing on his site is that

Dr. Carroll has kindly agreed that visitors to this website will not be charged the usual phone consultation fee of $78.
Use this unique opportunity to speak personally to Dr. Carroll for free.

If anyone wants to talk to the Dr for free (although I'm sure you'll probably get a sales pitch), here's your chance.

[Tim468]

Pheh!

I spend about 10 minutes up to 2 hours on the phone with patients every day, and that is not ever billed for, nor is it reimbursable through any major third party payer.

His "usual $78 fee"? Run the other way from this guy.

Tim

[gibson101]

Greetings
What is potaba and topical verapamil?? Have they had any positive effects at all?? Just curious...tryna gain as much nowledge as possible. Again if anyone here is from London could they please contact me!1

Regards

[hopeful]

Steve,

I went to see Carroll- lastyear- I cannot speak highly of him or for that matter Physion... He extracted almost $1700 from me-  just for his visit and test- No Soma- No Physion- No Verapaamil- In my opinion He is a prescription factory for Cialis, Viagra, etc... He doesn't even exam you- he has his assistant - which is the tech - stick your dick- and take measurements-Israel

As for physion.. I would strongly suggest that you contact them directly..and ask them for a LIST of docs that are using their system... according to what they have told me- it is only Dr. Carroll?- Carroll comes from a background similar to the Boston Clinic for Men- at one time he owned 18 centers... Do your homework! www.physion.com

Hopeful

[hopeful]

Lets get a copy of the study??

Hopeful

Not sure why this made the news, as I've seen these results at least a year ago...

Orlando, FL (PRWEB) November 28, 2006 -- Dr. George Carroll, specializing in the diagnosis and treatment of male sexual dysfunction for over fifteen years, is pleased to announce that preliminary studies using eletromotive drug administration (EMDA) have demonstrated encouraging results in the treatment of Peyronie's Disease. Dr. Carroll has found that the use of EMDA is especially effective in the treatment of the early stages of this pathology....

[Peregrine]

I've an opportunity to try verapamil injections -- 6 every other week -- while taking viagra, pentox and l aarginine.  Any experience with this?

[Old Man]

Perigrine:

There is a lot of information on this forum elsewhere about the verapamil injections. Many guys have tried them with some success and others with no success. I did 12 of them only to get more nodules and plaque from them. You should search back through the topics to find more from others.

Try doing a search engine by the topic of verapamil injections. It should bring up a whole bunch of posts about verapamil.

Regards, Old Man

[Peregrine]

I'm considering injections of verapamil (6 every two weeks) in combination with viagra, pentosyphlene and L-Argininge.  It's a 12-week process at a major university.  Any experience of improvement with this or similar procedure?

this post moved from the "Improvement" topic by Hawk

[Hawk]

I know of no one that has used Verapamil Injections (VI) in conjunction with the 3 oral treatments.

There is a survey on the PDS website showing responses from a VI survey.  

Although VI has questionably results alone, I would be tempted to give it a try.

[Peregrine]

There is an abstract on the web on PubMed Central of an article by Jalkut, Gonzalez-Cadavid and Rajfer, Department of Urology, UCLA. (Rev Urol, Summer 2003)  "60% had an objective decrease in curvature...." w/ intralesional verapamil.  I think the injections were accompanied by the oral viagra, pentoxyphylene, and L Arginine.

[Hawk]

Can you post a link right in your post?

Also look at our unscientific survey.

[Peregrine]

The website is:  http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1473022

[Crook]

Doesnt topical Verapamil work??
http://www.pslgroup.com/dg/1ce5c6.htm

[Steve]

Hi Crook,

Welcome to the board!

Well, our own (admittedly unscientific) survey indicates that Topical (or TransDermal) Verapamil (TV) has very limited if any success.  I think you can find a link to the surven on the 'Recently Diagnosed' section.

I'm not sure of this Dr. Fitch, but PDL makes money (by charging a LOT of money) by selling Topically applied Verapamil.  As such, I'd take any claims of success from them with a very large grain of salt!

Steve

[JW]

ComeBackid,

I also did the iontophoresis treatment and didn't notice any improvement.  The down side (besides the not insignificant cost and the general wierdness of running a minor current through your penis) was that I found it difficult to do iontophoresis and be as diligent about taking my potaba, which I think seems to help in my case.

I wonder if there are enough people who have tried iontophoresis to get some survey results?

JW

Tim,

After seeing our own poll results form the verapamil injections I have long pondered was it simply the needle that made the condition slightly get better.  "slight improvment," was the common good response from people.  The majority in our poll seemed to not improve or get worse, while a few slightly improved, and almost no one healed or got really better.  This leads me to believe that the needle injections maybe have slightly broken up some of the hardened tissue and plaque for a slight improvment, with the verapamil doing virtually nothing. These needle injections may have acted as a minor lariche like technique.

Look at the Iontophoresis, no results for me and Tim, and now a spanish study citing that no one got better after decadron and verapamil usage.  I've always had doubts about the PHYSION company, look at their cheesy website? I bought the machine out of hope and the successful studies that were out there.  I think the issue here, and this is just my gut feeling, is an issue of integrity in this case.  For every REALLY GOOD doctor like Tim, how do we know there isn't a cheating lieing son of a #@$@# out there?  I must remind everyone that another company had a product they claimed worked, Dr. Fitch even published a report citing high efficacy rates, speaking of PDLabs...

ComeBackid

[Kimo]

Steve,,I've been silent for sometime because of other health problems, but i must jump in here and tell everyone again that i had very good results from using Topical Verapamil....I was very badly bent and twisted like a donut and i used the topical for 5 months and it brought me back to about 85% straight,,,a year later i went back on it for a whole year and it completly broke up my plaque and just left me with what seems like scar tissue...I'm straight enough for intercourse and no pain....And yes i did purschase my stuff from Peyronies Disease Labs back then and it was expensive but my insurance did pay for most of it because my URO had wrote a letter to the ins company stating that peyronies does cause ED and so there fore they covered most of my expensenses....I know that there is a lot of negative input on the Topical,,,but mine was positive,,,,,,,,KImo        

Hi Crook,

Welcome to the board!

Well, our own (admittedly unscientific) survey indicates that Topical (or TransDermal) Verapamil (TV) has very limited if any success.  I think you can find a link to the surven on the 'Recently Diagnosed' section.

I'm not sure of this Dr. Fitch, but PDL makes money (by charging a LOT of money) by selling Topically applied Verapamil.  As such, I'd take any claims of success from them with a very large grain of salt!

Steve

[JAKE52]

Steve,

How far along (from inititial injury/diagnosis) were you before you began the topical verapil treatement, and how severe was you Peyronies Disease? (bed, indentation, hourglass, loss of size, loss of erections, etc.") if I'm not being to personl asking here!

[Steve]

Hi Jake,

Well, we do get kinda personal around here--it's the nature of the beast!

I started with Topical Verapamil (TV) about about 5 months after the injury that caused my Peyronies Disease, and about 3 months after the symptoms appeared.  What caught my attention was a sudden appearance of a 70 degree upturn right behind the Glans!  I'd never measured length before (or at least never remembered any measurments ) so I don't know if I've lost length (probably, but then again, how do you measure around the curve?  On the top (shorter I'm sure), on the bottom (maybe the same), or somewhere in the 'middle').  After I started the Verapamil Injections (VI), I noticed the start of some waisting/hour-glass deformation.  As far as erection 'quality' goes, it seems to be about the same as before Peyronies Disease started--except for the bend and hourglass!

As you can see from my signature, I haven't seen any improvement from the TV or IV, and now I'm on the long-term VED (Vacuum Erection Device) treatment, but I still haven't seen any improvement from that either.  Bummer  

Steve

[voulezvous]

Hello.

I am obviously a "newbie" but, I gotta say, there seem to a whole lot of us either viewing as members or as guests. I hear 3-4% of the male population is affected. Judging from what I've seen here over the past month, there are a lot of unreported cases.

Anyway. I'm here to ask a question about injections. I have had a series of 6 shots through the VA here in Minneapolis & I'm trying to decide whether or not to continue. I believe that there has been improvement in the "hardness" of the plaque but see no change in my curvature. Is this typical?

I'm also seeing a private urology group physician who is aware of the injections but doesn't give them. He's not trying to talk me out of continued shots but also is offering iontophoresis as an alternative.

I'm not asking to be told what to do here but would appreciate any feedback in support or otherwise of both approaches.

Thanks & thanks to all who make this forum possible. I can't express how much education I have received.

As a final note, I recently started seeing a much younger woman & we had a teriific attraction from the start. I finally screwed up my courage to tell her about Peyronies Disease &, just as has been stated many times by both men & women who write in, she accepted it as less important to the future of our relationship than I would have imagined. So often, our shame is within our own heads & bears no connection to reality.

Alan

[Steve]

Bon Jour Voulevous (sorry, that's the extent of my French).

Welcome to the forum -- you've come to the right place for information/suggestions/a shoulder to cry on.  Also, congratulations on discovering that women really can be understanding .

As far as the injections go, I went through 12, and never saw any effect (other than some really bad bruising), I think others may have had some more positive results.  Also, although I wanted to start off with Ionto, my Uro was unfamiliar with it.  Now, here on the forum, I see that those who've used it haven't seen the results that they were expecting, so maybe I didn't miss out on anything there.  Then again, nothing I've personally tried has yet to show any positive results, so maybe Ionto might do something .  Anyway, I'm sticking with the VED right now to give it a good long chance to do something.

Good luck in your journey.

[hopeful]

Alan,

This is Hopeful..,I would love to find a true uro that has used IONTOPHO.. can you please post his name and contact info..

Hopeful

I'm also seeing a private urology group physician who is aware of the injections but doesn't give them. He's not trying to talk me out of continued shots but also is offering iontophoresis as an alternative.

[Angus]

..... So often, our shame is within our own heads & bears no connection to reality.

Alan

  Welcome, Alan. Your statement is so often true. I am so glad you communicated with her. Long ago, Peyronies Disease was my dread secret. When I finally opened up and talked about it, to my surprise it was no big deal to her, so for years I had much ado about nothing, so to speak. Hiding and masking the condition is a huge source of stress and anxiety for men who have Peyronies Disease, I believe.
  More on topic re: shots; not long after Peyronies Disease was diagnosed I had one steroid injection into the plaque. This was many years ago. The plaque hardness subsided during the next year or two, but I can't say if that was a result of the injection or not because it was such a gradual process. The bend did not improve during that time. I only had the one shot, and no experience with iontophoresis.
 Welcome to the board... there is a LOT to read here!

[voulezvous]

Thanks to you folks who have so graciously responded.

I have scheduled another series of 6 shots. Angus, it may be that what happened with you will also be the case for me but, at this point, I'd rather see blue sky than rain. Time (I guess) will tell.

I forgot to mention in my 1st message that the private urologist also "sold" me a VED (I'm on M'care, thank God). Its the Osbon manual model but I haven't quite figured out how it works. I know that the key is to go slow. Again, my sense from everything I have read on this forum in the past is that it is not likely to hurt & may, in fact, help.....especially in stretching the hopefully softening plaque.

I'll keep you posted.

Alan

[Angus]

....I forgot to mention in my 1st message that the private urologist also "sold" me a VED (I'm on M'care, thank God). Its the Osbon manual model but I haven't quite figured out how it works...

  You need to camp out in the VED thread for information on the VED protocol that a lot of us use. It would be a good idea to read the Highlights of VED and Other Contraptions post in the Highlights section of the forum. If you use the Search function in the VED main thread you can find the protocol and get most of your questions answered; of course you should read the whole thread, but it may take you a while. If you have questions, ask away in the VED thread and you'll get useful, informative answers from members.

[kenno]

How do you buy Topical V?  I will search the forum for more information but thought I'd ask you since you seem to be familiar with it.

[kenno]

No statistical difference between verapamil and saline:

http://www.urotoday.com/42/browse_categories/erectile_dysfunction_ed/verapamil_versus_saline_in_electromotive_drug_administration_for_peyronies_disease_a_doubleblind_placebo_controlled_trial.html

[Kimo]

Kenno, as far as i know you need a prescription from your URO to get it. When i got it , it came from Peyronies Disease Labs in San Antonio, Texas....I know that a lot of the men don't believe in it, but it did work for me, i also did take a natural vita-E with it,,while on the topical i was taking 800 iu a day...I found the best price on the natural E at GNC.....I buy all my vitamins and supplements there....,,,,,if i can help in any other way just send me a PM and i will try to be of help,,,,,,Kimo

How do you buy Topical V?  I will search the forum for more information but thought I'd ask you since you seem to be familiar with it.

[Tim468]

Latest update I got by searching for new article on Peyronie's Disease weekly:

AU Russell S.  Steers W.  McVary KT.
FA Russell, Shane.  Steers, William.  McVary, Kevin T.
IN Department of Urology, Feinberg School of Medicine, Northwestern
 University, Chicago, IL, United States.
TI Systematic evidence-based analysis of plaque injection therapy
 for Peyronie's disease.[see comment]. [Review] [57 refs]
CM Comment in: Eur Urol. 2007 Mar;51(3):601-3; discussion 603-4;
 PMID: 17084959
SO European Urology.  51(3):640-7, 2007 Mar.
AB OBJECTIVE: We evaluated the peer-reviewed urology literature for
 intraplaque injection of medication for Peyronie's disease and
 assessed the quality of studies via rigorous evidence-based medicine
 criteria. METHODS: We performed a search of peer-reviewed literature
 looking at all agents used to treat Peyronie's disease by
 intraplaque injections. These were then evaluated using the Oxford
 Centre for Evidence-Based Medicine criteria, which ranks studies
 from strongest (level 1) to weakest (level 5) strength of evidence.
 RESULTS: Of the 19 studies found involving injection therapy for
 Peyronie's disease, 17 showed positive results. Six studies using
 injectable corticosteroids were identified and though all showed
 positive results, they were of level 4 quality. Two collagenase
 injection studies (one level 4 and one level 2 study) were
 identified, both of which showed positive results. All four
 verapamil injection studies found (three level 4 and one level 2
 study) showed positive results. Seven papers involving interferon
 alpha2-beta injections were evaluated (six level 4 and one level 1
 study), five of which showed positive outcomes and two of which
 showed no significant benefit. CONCLUSIONS: Ninety percent of the
 studies regarding Peyronie's disease showed positive outcomes.
 Unfortunately, most of these have not offered convincing
 evidence-based data, with only one positive study meeting level 1
 Oxford criteria for clinical efficacy. Standardised outcome measures
 were not used, making comparisons difficult. These results reveal
 the need for the development of validated outcome measures and
 well-designed controlled trials to determine optimal therapeutic
 intervention for this disorder. [References: 57]

[IEDCL]

My Uro prescribed Topical Verapamil from PDLabs. I am willing to make the $200/month investment if this treatment bears promise.Any testamonials out there...one way or the other ?

[Hawk]

IEDCL,

There are TONS of comments on topical Verapamil and PDL Labs on this forum, including a topic specifically on PDL Labs.  I suggest you read this topic and the PDL Labs topic.  You can also do a search on either TV, Topical, or PDL.  You will find plenty.

[Doug]

I've had some type of Peronies' for 2 or 3 years now. My Uro calls it a congenital form, with no real plaque at first and no trauma that I can remember. I started out with some curvature, then an indent which now forms a band about half way around, and creates some waisting. Things have developed fairly slowly for the most part. I'm still functional sexually, but have lost a little length. Then I developed a small lump or plaque, so my Uro said it was time for a verapamil injection. The next time I had an erection after the first verapamil injection (less than 2 weeks later), I noticed that the waisting had progressed a lot. Now it was also on the other side, almost encircling the whole penis.

I looked at all the posts here, and noticed that nobody seems to keen on the injections. Read one in particular from Hawk that sounded similar to my situation. I saw your survey too, and it doesn't look too good, although there are not a lot of responses. Anybody else had this problem? And Hawk, what direction did you take after that experience? I'm also taking Vitamin E, Carnitine and using topical verapamil. After being quite stable for a long time (or at least progressing slowly), things are going downhill very quickly, and like a lot of people who post here, it worries me.

I've been on anti arrhythmics and blood thinners for a few years, and I have a suspicion that the Peyronies is tied into the decreased blood flow to the penis from the anti arrhythmics. I've also been taking Viagra to counter the anti arrhythmics, so I wonder if it didn't play a part in this. But I can't find a doctor who agrees with any of this. Don't know if anyone else has any of these suspicions.

thanks

[Liam]

No No No  

I was not there with your doctor.  I will not judge.  Sometimes doctors tell us what they think we can understand.  I used to have a doctor that talked to me like I was an idiot.  He misdiagnosed me and I called him on it ( in my usual kind manner.... no, honestly).  Needless to say, I changed doctors.  Sometimes they rattle of technical jargon until its hard to understand.  Often times that is medical double talk.  Whatever the case, there is no congenital Peyronies Disease.  There can be a congenital curve.  There are a host of things that can go on with Wee Winky.  You could have had a congenital curve and later developed Peyronies Disease.

It is important for doctors to understand the process of Peyronies Disease and use the proper descriptive language.

Doug, I'm not going off on you in the slightest.  If a doctor actually said (and literally meant) that crap, anything that followed would be suspect.

Liam