Peyronies Society Forums

Please login or register.

Login with username, password and session length
Advanced search  

News:

ALL Members PLEASE Add a Signature line with age, history etc
PROFILE -> FORUM PROFILE -> SIGNATURE
More instructions here -> Signature Line - History - Peyronies Society Forums

Pages: [1] 2   Go Down

Author Topic: Mediwound MWPC003 for peyronies!  (Read 11574 times)

0 Members and 1 Guest are viewing this topic.

Youngdude22

  • Voting Member
  • **
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 35
Mediwound MWPC003 for peyronies!
« on: August 23, 2015, 07:58:10 PM »

Pipe Line | MediWound

Form 6-K MediWound Ltd. For: Jun 04

As of now there is a limited amount of information available about their peyronies product MWPC003. It looks like MWPC003 is at the bottom of their product pipeline unfortunately, nonetheless it seems promising considering the efficacy of there other products.
Logged

Freemason

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 160
Re: Mediwound MWPC003 for peyronies!
« Reply #1 on: August 27, 2015, 04:51:22 PM »

Looks like this company will likely start Phase 1 of this compound late 2015 or early 2016 based on company prospectus I read. Good to see others are still fighting for us.
Logged

Crooked_Stick

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 104
Re: Mediwound MWPC003 for peyronies!
« Reply #2 on: April 22, 2016, 10:49:37 AM »

I listened to Mediwound's conference call yesterday, seems they will be starting a small trial for their injectable bromelain based drug later this year. It is an exciting development for Peyronie's Disease, dupuytrens and other connective tissue disorders. Ex-vivo tests suggest the drug can dissolve fibrotic tissue without harming regular tissue.

This is an excerpt from the call:

  Do you still expect that MWPC003 program will begin clinical studies by the year-end? And if so, what do you need to accomplish between now and then?

--------------------------------------------------------------------------------

Gal Cohen, Mediwound Ltd. - CEO [46]

--------------------------------------------------------------------------------

So, first of all, we are very excited about that because we really want to have an injectable form of technology because of the vast opportunities around that. I mean just look at the other companies that use enzymes for connective tissue disorders and you see dupuytrens, Peyronie's, (inaudible) and cellulitis and so many potential indications.

We are shifting a little bit of resources toward that product now that we have BARDA funding the NexoBrid program. We are in the process of finalizing a formulation, an injectable formulation. We will do small clinical studies because, again, we are talking about in these indications of parts of milligrams.
Logged

pfract

  • Think Tank
  • **
  • Country: ca
  • Offline Offline
  • Gender: Male
  • Posts: 1547
  • #whateverittakes
Re: Mediwound MWPC003 for peyronies!
« Reply #3 on: April 22, 2016, 05:16:00 PM »

These are some good news right here. Hope it gets through!

Crooked_Stick

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 104
Re: Mediwound MWPC003 for peyronies!
« Reply #4 on: April 23, 2016, 12:15:12 PM »

In my opinion this is the most important research being done for Peyronies Disease. Every other intra-leasional injectable has serious drawbacks....I'm halfway through the Xiaflex treatment and I have seen zero improvement. Xiaflex seems to do little to break down the plaque.

Anyway I would encourage everyone to contact the Investor relatiotions dept. of Mediwound and let them know how important their work is.
Logged

pfract

  • Think Tank
  • **
  • Country: ca
  • Offline Offline
  • Gender: Male
  • Posts: 1547
  • #whateverittakes
Re: Mediwound MWPC003 for peyronies!
« Reply #5 on: April 23, 2016, 02:03:06 PM »

Who knows, maybe a combination of both in the future? But indeed, great news!

edzo67

  • Voting Member
  • **
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 65
Re: Mediwound MWPC003 for peyronies!
« Reply #6 on: April 25, 2016, 03:43:10 AM »

i sent an email to mediwound to volunteer for trials . havent heard back
Logged

Crooked_Stick

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 104
Re: Mediwound MWPC003 for peyronies!
« Reply #7 on: April 25, 2016, 10:25:44 AM »

It would probably be better to call....I haven't had any luck emailing them either.

Anne Marie Fields
T: 212.838.3777

It would be great to know who and where the trials will be conducted!
Logged

Jack1909

  • Major Contributor
  • ****
  • Country: it
  • Offline Offline
  • Gender: Male
  • Posts: 460
Re: Mediwound MWPC003 for peyronies!
« Reply #8 on: April 26, 2016, 02:25:09 AM »

Unfortunately phase 1 means we will not see anything before 2020...
Logged
Please go to PROFILE then FORUM PROFILE to replace this signature line text with your profile info such as
age, date of onset, symptoms, treatments tried,
relationship status, etc
** You will waste less time and get better answers **

popopo

  • Major Contributor
  • ****
  • Country: nl
  • Offline Offline
  • Gender: Male
  • Posts: 544
Re: Mediwound MWPC003 for peyronies!
« Reply #9 on: April 26, 2016, 04:30:20 AM »

2020, that sounds way too early. I'm sure they'll make us wait longer than that. Maybe I can finally get it when I'm 40. Hopefully I won't be TOO repulsive by that age.
Logged
Age: 25
Date of onset: 17
Symptoms: sharp pains, numbness, change in shape/size, hourglassing and discolaration from jelqing/VED usage as a teen. Diagnosed with a venous leak and possible scarring.
Treatments tried: cialis, pentox and VED didnt help

Jack1909

  • Major Contributor
  • ****
  • Country: it
  • Offline Offline
  • Gender: Male
  • Posts: 460
Re: Mediwound MWPC003 for peyronies!
« Reply #10 on: April 26, 2016, 07:33:07 AM »

In fact I think all the peyroines suffer should expect more from Atala and its stuff than from this..partial replacement will hit the market first for sure.
 
Logged
Please go to PROFILE then FORUM PROFILE to replace this signature line text with your profile info such as
age, date of onset, symptoms, treatments tried,
relationship status, etc
** You will waste less time and get better answers **

Crooked_Stick

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 104
Re: Mediwound MWPC003 for peyronies!
« Reply #11 on: April 26, 2016, 09:55:25 AM »

From the conference call they indicated that a lot of the pre-clinical work and research from their other products that use the same enzyme will allow them to jump right into Phase 1 trials probably next year. Yes it will be awhile before this is approved (2020-2021) but it is what it is. There just isn't a cure out there in 2016.  I've been dealing with this curse for four years now some I realize that patients is needed.
Logged

popopo

  • Major Contributor
  • ****
  • Country: nl
  • Offline Offline
  • Gender: Male
  • Posts: 544
Re: Mediwound MWPC003 for peyronies!
« Reply #12 on: April 26, 2016, 12:29:57 PM »

Yes, I also have this condition for four years now. Some guys are on this forum for way longer than that tho.. I agree that the worknof dr.atala seems more promising for a real cure, but I can hardly imagine something so complicated will be widely available soon. I also didny get a reply when I emailed wake forest. Anybody here who had more luck contacting them?
Logged
Age: 25
Date of onset: 17
Symptoms: sharp pains, numbness, change in shape/size, hourglassing and discolaration from jelqing/VED usage as a teen. Diagnosed with a venous leak and possible scarring.
Treatments tried: cialis, pentox and VED didnt help

Jack1909

  • Major Contributor
  • ****
  • Country: it
  • Offline Offline
  • Gender: Male
  • Posts: 460
Re: Mediwound MWPC003 for peyronies!
« Reply #13 on: April 26, 2016, 02:38:35 PM »

Widely available not, but I do believe that Atala can do it right now. The problem is the FDA approval...

I've been having an unusable penis since the day I started to look for girls. I was 16 and now I am about to turn 26. In the meanwhile..no sex, no relations. We are all on the same boat, teammates in this disgrace.
Logged
Please go to PROFILE then FORUM PROFILE to replace this signature line text with your profile info such as
age, date of onset, symptoms, treatments tried,
relationship status, etc
** You will waste less time and get better answers **

Crooked_Stick

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 104
Re: Mediwound MWPC003 for peyronies!
« Reply #14 on: June 06, 2016, 02:09:29 PM »

An update on progress of  injectable bromelain solution (IBS, or MWPC003). I think this could very well be the magic bullet you guys. I know it could be awhile but this stuff can completely dissolve the fibrotic plaque WITHOUT damaging healthy tissue. Links:

 Data Published in Bone & Joint Research Supports MediWound's Bromelain-Based Enzyme for the Release of Dupuytren's Contracture (NASDAQ:MDWD)

A new bromelain-based enzyme for the release of Dupuytren’s contracture | Bone & Joint Research



Logged

krazylord

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 164
Re: Mediwound MWPC003 for peyronies!
« Reply #15 on: June 06, 2016, 07:10:48 PM »

Good news! Hope that it comes available to the public soon.
Logged

gringoviajero

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 106
Re: Mediwound MWPC003 for peyronies!
« Reply #16 on: July 05, 2016, 03:08:16 PM »

I just noticed somebody started a thread on Mediwound. I was telling you guys about their bromelain-based injectable back on 7 December 2014 when I was self-injecting bromelain. Their patent application is interesting, if you haven't read it already. The big question is how will Xiaflex' orphan drug status impact them? The market is enormous.  My last Xiaflex shots were over ten grand EACH.

I'm going back to bromelain myself but strictly topical.  Dr. Carrion recommends against getting the last Xiaflex injection, although it's my call, because of my 2 injection-related surgeries.  This time I'll try 5% bromelain in a base of Lipoderm HMW (high molecular weight) after I've fully recovered from the last surgery 9 weeks ago.
Logged

kuaka

  • Major Contributor
  • ****
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 631
Re: Mediwound MWPC003 for peyronies!
« Reply #17 on: July 05, 2016, 03:54:48 PM »

From the mixed results of Xiaflex reported here, I am disinclined to even consider it.
Logged

gringoviajero

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 106
Re: Mediwound MWPC003 for peyronies!
« Reply #18 on: July 05, 2016, 07:36:37 PM »

The problem is there are so many variables and so many unknowns that it's hard to predict an outcome.  The benefits I had from the 2nd cycle – reduction of angle and indent – have remained.  Dr. Carrion said mine was one of his most complex cases.  The plaque is soft and runs nearly the entire length.  As he asked himself aloud after first examining me, So where do I put the needle?  Guys with one small hard plaque have a better chance.  There are a couple of us here with the same plaque; JobinSpain and YYY, I think.  My surgeries were just bad luck.

What makes Xiaflex so dangerous is also what makes it your best shot, aside from surgery: it's powerful.  Softening collagen fibers is no easy task.  It's like using sulfuric acid to remove a wart.  My advice is go to the best doctor you can find and let him or her advise you.  I do not hesitate to recommend Rafael Carrion with USF Health in Tampa.  And if I had it to do over again, I would.  Aside from a Nesbitt or implant, nothing's going to help me.
Logged

lgrace

  • Voting Member
  • **
  • Country: fr
  • Offline Offline
  • Gender: Male
  • Posts: 21
Re: Mediwound MWPC003 for peyronies!
« Reply #19 on: September 23, 2016, 12:42:51 PM »

The ex vivo trials for this and LOS seem quite promising.

However, does anyone know how Xiaflex did in the tests at the same stage?
Was it also as promising in the beginning? (Before it proved to be very moderately effective - at best - in the end)
Logged

Crooked_Stick

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 104
Re: Mediwound MWPC003 for peyronies!
« Reply #20 on: September 24, 2016, 11:17:58 AM »

Not that sure about the early history of  Xiaflex but MWPC003 has distinct advantages over Xiaflex because it is proven to not harm normal tissue and blood vessels. They use huge quantities of the stuff for debridment of burned skin. Xiaflex dissoles the plaque but also damages the surrounding tissue so that new scar generally forms and because of this only small amounts of Xiaflex can be used wheras with the bromelain based enzyme you can use much larger amounts which will dissolve more plaque. The bromelain itself inhibits scar formation as an added bonus. They already have the injectable form of MWPC003 ready to go. They were hoping to do some hind of small trial on dupreynes late this year.
Logged

beechcott

  • Voting Member
  • **
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 33
Re: Mediwound MWPC003 for peyronies!
« Reply #21 on: September 24, 2016, 12:36:42 PM »

Is there any data on whether this product will dissolve calcified plaques?
Logged

kuaka

  • Major Contributor
  • ****
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 631
Re: Mediwound MWPC003 for peyronies!
« Reply #22 on: September 26, 2016, 10:10:49 AM »

Is calcification an issue with Dupuytren's?  If not, I doubt they are looking at that for the time being.  I would be game for a trial of this product for Peyronies Disease though...
Logged

lgrace

  • Voting Member
  • **
  • Country: fr
  • Offline Offline
  • Gender: Male
  • Posts: 21
Re: Mediwound MWPC003 for peyronies!
« Reply #23 on: September 30, 2016, 05:48:27 AM »

What I find less encouraging is that in some ex vivo studies, Xiaflex seems to also dissolve/degrade scar tissue :

http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0156428

But as said before, Xiaflex also dissolves healthy tissue, so I hope that Mediwound will succeed where Xiaflex failed.
I certainly do hope they go on with the studies on Dupuytren and Peyronie, and that the product keeps its efficiency throughout human trials.
Logged

Nemo

  • Major Contributor
  • ****
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 703
Re: Mediwound MWPC003 for peyronies!
« Reply #24 on: September 30, 2016, 05:20:09 PM »

As depressing, demoralizing and discouraging as Peyronie's is, I think we should be thankful that we're living in a time when products like Xiaflex and hopefully Mediwound are making it to market. It is not beyond the realm of possibility that we will see Peyronies Disease cured in our lifetime, though I know that for the worst-off of us, this is not fast enough. It gives me hope though.

For instance, 15 years ago, when I had my first run-in with Peyronies Disease, there wasn't anything available more "hard-hitting" than Topical Verapamil - and we all know how that proved to be a huge waste of time and money. Things like Xiaflex and Mediwound are taking the fight chemically directly to the Peyronies Disease plaques. Let's hope Mediwound lives up to its promise!

Nemo
Logged

Crooked_Stick

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 104
Re: Mediwound MWPC003 for peyronies!
« Reply #25 on: October 13, 2016, 11:22:07 AM »

I continue to believe that the product being developed by Mediwound could be a major breakthrough for Peyronies Disease. I also think there could be some value in developing a relationship between this board and the company(Mediwound). Mediwound is a small company with limited funding. We may even be able to set up a charity through this site that could provide funding for trials that would help to speed up the release of MWPC-003. We would need someone in an authoritative position associated with this site to act as our representative, make contacts and figure out how we, collectively, can help. Any thoughts?
Logged

kuaka

  • Major Contributor
  • ****
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 631
Re: Mediwound MWPC003 for peyronies!
« Reply #26 on: October 13, 2016, 05:33:01 PM »

I like the idea.  This forum could easily be a source of trails volunteers and if the trials go well, customers and spokespersons. 
Logged

Gutted

  • Solid Contributor
  • ***
  • Country: gb
  • Offline Offline
  • Gender: Male
  • Posts: 212
Re: Mediwound MWPC003 for peyronies!
« Reply #27 on: October 13, 2016, 05:52:53 PM »

I agree .... good idea !

I've been researching MWPC003 and the company a lot myself. I noted in one of their NASDAQ Analyst briefings that they were actually targeting Dupuytren's Contracture and Peyronies Disease with this development but I think they are underestimating the size of the Peyronies Disease market. Personally, I think there are a lot more cases than 8% of men over 50yrs old. I think many don't talk about it and don't seek medical attention out of embarrassment or other issue. There seem to be many men in their 40's with it and also many younger guys from injury or penis enlargement gadgets.

I think a single approach from this Forum would help them see the scale of this market and furnish them with a lot of data (anecdotal or otherwise) and volunteers !!! 
Logged

Freemason

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 160
Re: Mediwound MWPC003 for peyronies!
« Reply #28 on: October 14, 2016, 12:41:02 AM »

We could do a crowd funding site? Or go fund me page?  Sure it's expensive to conduct clinical trials..I should know I work for a large Pharma company but as we all know if the product works even moderately it is a multi multi million dollar product.
Logged

Crooked_Stick

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 104
Re: Mediwound MWPC003 for peyronies!
« Reply #29 on: October 14, 2016, 12:26:34 PM »

I have personally tried to contact Mediwounds IR in the past, with no response. I believe we have to have the person that is the head of Peyronie's Disease Society make the first contact. I guess that would be Larry Holcombe (Director, Peyronie’s Advocacy Group Peyronies Disease Society)....so if we can get him onboard then we have a starting place.
Logged

Shankerbill

  • Voting Member
  • **
  • Country: gb
  • Offline Offline
  • Gender: Male
  • Posts: 25
Re: Mediwound MWPC003 for peyronies!
« Reply #30 on: October 16, 2016, 05:22:49 PM »

A very interesting thread right through from Youngdude's initial post. I agree with Gutted, the figure of 8% of men over 50 with Peyronies Disease is probably a low estimate. I guess there are lot in that over 50 age group, as we read about here, who have the disease, but without severe bending or indent or pain, just hidden fibrotic or scar tissue or plaque. I have the dorsal curve and indents, but besides this, the Erectile Dysfunction and the increasing loss of sensitivity is becoming a real problem for me. Both of these I ascribe to Peyronies. I am considering Xiaflex, but am put off by the damage it can do to normal tissue and cost. It does strike me that Mediwound's MWPC003 could become beyond being a cure for Peyronies and it's symptoms, almost a 'Spring-clean' or re-furb for the penis, restoring a degree of sensation and erectile capability. If it leaves normal tissue unharmed and is capable of clearing fibrotic tissues and calcifications it could be the biggest thing for males since viagra.
Logged

LeeBee69

  • Voting Member
  • **
  • Country: au
  • Offline Offline
  • Gender: Male
  • Posts: 54
Re: Mediwound MWPC003 for peyronies!
« Reply #31 on: October 16, 2016, 08:01:36 PM »

I love the idea Crooked Stick and would support the charity/fund, etc.

Cheers,
LeeBee
Logged

LWillisjr

  • Administrator
  • *****
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 2827
  • 62 y/o - 10 yrs Peyronies free
    • My Peyronie's Story
Re: Mediwound MWPC003 for peyronies!
« Reply #32 on: October 17, 2016, 07:28:46 PM »

I don't know that we have a chairperson for our Peyronies Disease Society site. I am the admin and we have a small group of active forum moderators. I know nothing of this site simply as I have not had time to research it yet.
Logged
Les - 10 yrs Peyronies Disease free
My History

kuaka

  • Major Contributor
  • ****
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 631
Re: Mediwound MWPC003 for peyronies!
« Reply #33 on: October 18, 2016, 04:11:46 PM »

Perhaps we could "organize" at that level?  Name a "President" of the group and have them approach Mediwound mfg with that title, and the numbers of men here?
Logged

james1947

  • Major Contributor
  • ****
  • Country: ro
  • Offline Offline
  • Gender: Male
  • Posts: 6679
  • Age 71. Peyronies from January 2009
Re: Mediwound MWPC003 for peyronies!
« Reply #34 on: October 19, 2016, 08:06:35 AM »

What is all about?
Can't find nothing about this product on they website!
Why we should contact them?


James
Logged
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

Gutted

  • Solid Contributor
  • ***
  • Country: gb
  • Offline Offline
  • Gender: Male
  • Posts: 212
Re: Mediwound MWPC003 for peyronies!
« Reply #35 on: October 19, 2016, 03:10:06 PM »

Like the red font there James !  ;D

Here is a market briefing from the CEO of Mediwound, albeit November 2014, but slides 4 and 5 make it clear that MWPC003 was in Pre-Clinical trials even back then. Those slides also make it clear that this enzymatic compound (Bromelain) is being specifically developed for connective tissue disorders and they are specifically targetting Peyronies Disease and Dupuytren's Contracture :

http://www.jefferies.com/CMSFiles/Jefferies.com/files/W%201500%205%20MediWound.pdf

Here is the latest info I have found, a very informative press release by Mediwound which will make the position very clear to all Forum members :

Data Published in Bone & Joint Research Supports MediWound's Bromelain-Based Enzyme for the Release of Dupuytren's Contracture (NASDAQ:MDWD)


Logged

pfract

  • Think Tank
  • **
  • Country: ca
  • Offline Offline
  • Gender: Male
  • Posts: 1547
  • #whateverittakes
Re: Mediwound MWPC003 for peyronies!
« Reply #36 on: October 20, 2016, 09:49:17 AM »

lol at the pun to james :D

Gutted, that was a pretty good find. There is a pretty good chance this product comes to the market in the future! Let's hope it's successful.

Ps: what about our pet project dude?

Crooked_Stick

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 104
Re: Mediwound MWPC003 for peyronies!
« Reply #37 on: October 20, 2016, 02:19:14 PM »

Another article for James  ;) :

https://www.ncbi.nlm.nih.gov/pubmed/26761870

This stuff can even soften beef and chicken! Could do wonders for your beef maybe James!
Logged

james1947

  • Major Contributor
  • ****
  • Country: ro
  • Offline Offline
  • Gender: Male
  • Posts: 6679
  • Age 71. Peyronies from January 2009
Re: Mediwound MWPC003 for peyronies!
« Reply #38 on: October 20, 2016, 07:42:41 PM »

Do you know that what they are injecting are chemicals?
To soften meat (I am a red meat lover) can just massage it, don't need to inject chemicals!!!
Anyhow, I am buying my beef fresh, know what to buy, it is always tender and soft.
Quote
Could do wonders for your beef maybe James!
Luckily "my beef" is still strong with the help of this blue miracle pill (buying white TEVA, much cheaper and white, acting on my beef better)

James
Logged
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

treeza1

  • Voting Member
  • **
  • Country: au
  • Offline Offline
  • Gender: Male
  • Posts: 28
Re: Mediwound MWPC003 for peyronies!
« Reply #39 on: October 22, 2016, 08:43:43 AM »

So if the plaque or plaques are completely dissolved with no further damage to surrounding tissue or recurrence of plaque what will to mean to the quality of erections? Will the penis be restored to its original pre peyronie's dimensions?
Logged

LWillisjr

  • Administrator
  • *****
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 2827
  • 62 y/o - 10 yrs Peyronies free
    • My Peyronie's Story
Re: Mediwound MWPC003 for peyronies!
« Reply #40 on: October 22, 2016, 06:25:14 PM »

In theory if you could completely dissolve the plaque without any other damage, then yes your erection should be restored to its pre-Peyronies condition.
Logged
Les - 10 yrs Peyronies Disease free
My History

james1947

  • Major Contributor
  • ****
  • Country: ro
  • Offline Offline
  • Gender: Male
  • Posts: 6679
  • Age 71. Peyronies from January 2009
Re: Mediwound MWPC003 for peyronies!
« Reply #41 on: October 22, 2016, 08:28:12 PM »

Also the length, girth and shape will be back treeza1

James
Logged
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

FriskyDingo

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 115
Re: Mediwound MWPC003 for peyronies!
« Reply #42 on: October 22, 2016, 11:04:28 PM »

Anyone know if this mediwound stuff will be capable of dissolving corporal fibrosis? From my understanding corporal fibrosis is still very important from a structural standpoint, and just getting rid of it is not a good idea.

Thanks
Logged

Freemason

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 160
Re: Mediwound MWPC003 for peyronies!
« Reply #43 on: October 23, 2016, 12:11:11 AM »

Ok..so here's my guess..This product they are looking to get approved in Europe..It will come to market much faster in Europe..obviously they will want to introduce it to the U.S. For big $$ but my guess is they will look to get it approved in Europe for DC and take the money to do a Phase 3 trial in the U.S...However nothing says we cant go to Europe to be treated.  Very encouraging indeed.  I take Bromelain sups but they prob arent getting to my Peyronies Disease at all..Wonder if you could some how make a cream from teh sups with DMSO and apply it.  Although i dont know if the molecule would be small enough to penetrate.
Logged

pfract

  • Think Tank
  • **
  • Country: ca
  • Offline Offline
  • Gender: Male
  • Posts: 1547
  • #whateverittakes
Re: Mediwound MWPC003 for peyronies!
« Reply #44 on: October 23, 2016, 10:13:15 PM »

Anyone know if this mediwound stuff will be capable of dissolving corporal fibrosis? From my understanding corporal fibrosis is still very important from a structural standpoint, and just getting rid of it is not a good idea.

Thanks
Hey.... Huh... Did you smoke anything before writing that or....? I would say you are so wrong....

nastyone

  • Voting Member
  • **
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 14
Re: Mediwound MWPC003 for peyronies!
« Reply #45 on: November 07, 2016, 01:36:31 PM »

I've recently tried contacting MediWound through email, as well as dr. Atala and whoever I could reach out who's doing the iMS Cell research at UNSW. No responses from any yet, except automated. I will definately try calling if I don't receive a response this week.
From what I've read on MWPC003, the trials stated that their compound can completely dissolve fibrotic tissue in more than 80% of cases, even with very small amounts used. And as stated earlier, this stuff is claimed safe, and even beneficial for inflammation and proper healing, which means large quantities could be used for better effect.
Just need to be persistent about inquiries into any possible clinical trials
Logged

Lucketts

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 101
Re: Mediwound MWPC003 for peyronies!
« Reply #46 on: November 07, 2016, 02:49:51 PM »



Good work nastyone.  Please keep trying, and keep us posted.  Never know if/when/where a solution to this disease will be found.
Logged

nastyone

  • Voting Member
  • **
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 14
Re: Mediwound MWPC003 for peyronies!
« Reply #47 on: November 07, 2016, 06:45:52 PM »

Yea. I think we all know there will be a complete cure for this one day, even if it does mean complete replacement. The issue is how long it will take, and when will there be effective treatment until then, that will atleast restore our quality of life.

Way I see it, contacting doctors and researchers about this can only help. Awareness is important
Logged

Dared

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 179
Re: Mediwound MWPC003 for peyronies!
« Reply #48 on: December 14, 2016, 01:04:02 AM »

What if you like 70% of my tissue is scarred. In doubt this would work because if all my plaques disappeared I would basically be castrated right?
Logged

LWillisjr

  • Administrator
  • *****
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 2827
  • 62 y/o - 10 yrs Peyronies free
    • My Peyronie's Story
Re: Mediwound MWPC003 for peyronies!
« Reply #49 on: December 18, 2016, 09:00:14 PM »

I don't think you are using the right term. Castrated is when your testicles are removed. Completely unrelated.
Logged
Les - 10 yrs Peyronies Disease free
My History
Pages: [1] 2   Go Up
 

Related Topics

  Subject / Started by Replies Last post
11 Replies
8629 Views
Last post February 20, 2014, 03:08:57 AM
by james1947
2 Replies
1999 Views
Last post October 06, 2012, 08:45:58 PM
by Sargonnas
0 Replies
2143 Views
Last post March 18, 2014, 10:47:08 PM
by james1947