It's more complex than we thought

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Axel_PD_Workbook

Based on my research and many conversations, I am more than convinced that micro-injuries play only ONE role in the development of Peyronie's disease. Rather, it is a "big picture" consisting of diet, especially sugar consumption, lack of (or very little) precautions for us men when it comes to penis health, (unhealthy) urban living, including stress, obesity, smoking and alcohol, and - yes - minor injuries from everyday life (ball sports) and "activities" during sex/masturbation that we classify as "normal" but are harmful to our best friend.
Diagnosis in early 2023 - cure (hopefully) in mid-2024. I have written a book about my experiences. Axel Westerwelle

Centurian25

Two things can be true at the same time

I guess one should ask does physical trauma always result in Peyronies?  ie does a penile fracture result in P.D. 100% of the time or does it vary?  If it varies this tells us there is more at play....

I believe many men with P.D. can't recall a physical trigger / accident.  If you were to suffer something like a penile fracture you would definitely recall it.....

I think it's likely a metabolic disorder that opens the door to the condition.  This explains why the typical sufferer is older and/or usually has other conditions (high blood pressure, diabetes etc).  The metabolic disorder makes the male susceptible to P.D.  Since we are all different, the metabolic disorder may manifest in other conditions (depending on the person).
Peyronies for 15+ years.  My old account on here is Overcomer and has details of what I what I went through

PleaseFindACure

I believe that Peyronies Disease describes a symptom, but not the cause.

There could be easily 10 different causes that lead to a scar inside the penis that all look like Peyronie's Disease symptoms.

A scar from an injury.
A scar from overheating the tissue from repeated friction.
A scar from tissue that was attacked by one of the gazillion autoimmune diseases out there.
A scar from a infection.
A scar that does not heal because of missing oxygen.
A scar that does not heal because of missing nutrients.
A scar that does heal too small due to missing erections that shape it.
A scar that does not heal due to issues in the immune system.
A scar that does not heal due to a conflicting medication.
...

With all these different possible causes it is super difficult to find one cure or one explanation. Let's hope that modern technology can solve the riddle by simulating and evaluating different scenarios that trigger fibrosis and prevent normal scars healing.
Mid 30s. 2021 Diagnosed Peyronies Disease&ED, 2023 Chronic.
Dorsal Plaque behind Glans with Hourglass, 1.5cm
Shortening and 15deg Curve up and left, OCD. Functional with Meds
Since 2023: Daily Manual Traction & 5mg Cialis, L-Arg., CoQ 10, Antioxidants.

Mikel7

The one thing you need to remember about peyronies is that there are no 2 men who react the same way to it. One may be diet another something else. I developed it without any known cause and I am healthy and exercise and careful then bam out of nowhere I got plaques and marbled cysts in penis. Then it deformed with an upward curve. I drove myself crazy trying to figure it all out. I then had to come to the realization of what was happening and educate myself because there are very few Dr's
who treat this intelligently. I did find a peyronies Dr and we worked together and I found what worked for me. I have regained almost everything back that I had lost and all of the plaques have dissolved.
Lump 4/2020, age 63 , Dr Levine 6-26-20, Dors Curve 11/2020, Peyronies
Vit E400mg, COQ10, Heat Therapy, Penimaster, Pentox, Cialis, Restorex
SNHL 7/2020 - Stopped all Meds because ototoxicity  Heat/traction/VED are working. CPPS Diagnosis - Stable :)

PleaseFindACure

Wow, did they dissolve in Chronic Phase or in Active Phase? I am long in Chronic Phase, I had improvements in the deformity, but I still feel the annoying plaque. Still on the hunt for a urologist that helps trying more.
 
For me what I try next are hormones checking (my Testosterone and Estradiol were low when the thing happened - my urologist was really bad and did not know the ranges for my age, now AI checked all my blood work and noticed it when I asked it about some more ideas) and potentially Penimaster Pro traction to re-gain length. But I am worried I am too late in Chronic Phase for these things to make a difference still.
Mid 30s. 2021 Diagnosed Peyronies Disease&ED, 2023 Chronic.
Dorsal Plaque behind Glans with Hourglass, 1.5cm
Shortening and 15deg Curve up and left, OCD. Functional with Meds
Since 2023: Daily Manual Traction & 5mg Cialis, L-Arg., CoQ 10, Antioxidants.

Mikel7

You are never too late for traction or even using VED. I would look a little more closely at your Testosterone levels especially your free T and your Estradiol levels.
Everyone is subjective and maybe what is normal for someone else would be low for you. Also finding a real hormone Dr for a man can be difficult. I have been on full Testosterone replacement for 21 years. You can DM me for more info if you want.....
Lump 4/2020, age 63 , Dr Levine 6-26-20, Dors Curve 11/2020, Peyronies
Vit E400mg, COQ10, Heat Therapy, Penimaster, Pentox, Cialis, Restorex
SNHL 7/2020 - Stopped all Meds because ototoxicity  Heat/traction/VED are working. CPPS Diagnosis - Stable :)