Hello,
I am age 54.
I will mention this for completeness, though it is unclear whether it is related to PDS: Several years ago, I began noticing an uncomfortable tingling in my penis after ejaculation. Eventually there was a general sensitivity and discomfort throughout the day.  It was never very painful, but highly annoying. I have no idea if this is related to PDS or perhaps something else. I think it may be some sort of neuropathy. Speculation: I am vegan, and for a while I was not supplementing B12 (this is one thing that vegans can become deficient in), and I read that B12 deficiency can be associated with nerve problems.  Or maybe it was some sort of early, pre-PDS phase?  So, this paragraph may be totally unrelated, but I included it as part of the history.  

October 2020, I noticed a distinct, painful tightness and upward bend in the penis when fully erect. There was no traumatic event associated with this, it just happened.  

So here is my current state:
I still have a general sensitivity most of the time.  It's worse after ejaculation. My frequency is about twice a week (masturbation). I have what I think is called hard flaccid: for me, if totally flaccid is 1, and ejaculation is 10, then much of the day my penis is semi-flaccid, maybe around a 3 or so. And touching it can be uncomfortable to a little bit painful. If it gets very hard, there is a slight upward bend, say up through hardness level 9. But if it gets to full 10, right before ejaculation, there is a distinct bend, at least 45 degrees, or more. And it is tight and hurts. The bend is about 2/3 of the way from the base to the tip (very typical of what I've read in here). It takes some concentration to be able to ejaculate without hurting too much, I don't know how to describe it. It may be I'm "relaxing" the hardness just a bit.  Regardless, the penis feels sore afterward, and it takes a few days before I feel like doing anything with it.  I have good NTE's, though now they tend to wake me up because they are somewhat painful.

I am doing lots of supplements (CoQ10, vitamin e, raw ginger, bromelain, but not all on the same day - don't want to overwhelm my body). Also some occasional, gentle, manual traction for a few minutes a day, 2 or 3 days a week.  I am not overweight, I am no athlete but I do some light exercise 2 or 3 times a week. The pandemic left me working at home, and (speculation) maybe the decreased physical activity (being stuck in one room most of the day) contributed to the PDS?  Or maybe it's just age. So, in addition to the supplements, I switched to loose pants, make sure I get up and move around every hour. Drinking: for many years, my routine was 2 or 3 beers on Friday night and Saturday night, rarely anything during the week.  Now I have mostly stopped drinking at all, to see if it helps. I'm already on a vegan, (mostly) whole food diet, from several years before PDS. So far, despite these measures, no improvement (but no worsening). Dick is still bent and sore.

Last summer, I had checkup and a full blood screen.  Blood pressure good. Everything (lipids, all of the other stuff I don't know what it is on the report) was healthy and in-range, except that I had a vitamin D deficiency (maybe due to lockdown?).  I started supplementing vitamin D starting in August.

I went to see a urologist.  He is recommending xiaflex and traction (restorex). He set an appointment for me to get formally "measured" (inject something to make me erect).  I asked him about doing an ultrasound, and he said it was not necessary.  He also stretched and squeezed my penis to check for plaque, which was very painful. I don't know what he could have found, I do not notice a "bump" or anything, but maybe it takes that amount of squeezing to feel it.  I am still a little wary - shouldn't I get an ultrasound?

I have a few other questions, but I think perhaps I should ask them in separate posts, to avoid too much info and losing focus.

Welcome to the forum. If you haven't done so you might read the following which will provide quite a bit of basic information.

https://www.peyroniesforum.net/index.php/topic,3180.0.html

Welcome to the forum CurvyBurt.

I have known about the vitamin D blood serum levels of about 15 people.  Fifteen out of fifteen were on the edge of deficiency and nowhere near-optimal levels, so I am sure you were like that long before the lockdown.  The only way you would not be is if you are in the habit (literally) of laying on the beach nude without sunscreen at noon a few days a week.  You likely need at least 5000 IU a day to stay near low-optimal levels, and it will take some time to bring it up. With or without Peyronies Disease, it is the single most important vitamin you can supplement as it functions more like a hormone than a vitamin.

If you are taking the doses recommended in the link that LWillis gave you, there is no need to rotate.  They are food-based nutrients, so they are not going to overwhelm your body.

One other thing - it will make a world of difference in how much help you get if you will fill in your signature line.  It helps us help you and shows some consideration by saving us from asking the same questions repeatedly.  Please read this - https://www.peyroniesforum.net/index.php/topic,10819.0.html

Thanks

Hawk

Welcome aboard Curvy! I hope you are able to get some sollace and support here with us.

I add that while not being vegan myself, i do have a lot of stuff you guys have too. Lentils, chick peas, tofu, tempeh sometimes.... good stuff!

For what it is worth, I just heard a report on a 10-year study on vegan vs meat-eating.  A few interesting points:

Only 1/2 of 1% of the population in the world are vegan. Approximately 80% - 90% of vegans and vegetarians abandon the diet and return to regularly consuming small quantities of meat.

Vegans have higher health risks in several areas including significantly higher stroke risk and more broken bones.