I feel like there's no point to life anymore, there's no hope

[Florida]

I'm 29 and healthy but now I have both extreme tunica and corporal fibrosis. This came from an injury back in November of last year (month 9 now). I'm on daily 5mg cialas, pento, and colichicine, q10, NAC, ALC, Vit e, and other Peyronie ones but is only slowing the fibrosis, and I'm losing function.

At first I just lost erections for a month from injury but then it came back although weak it eventually got better till month 5 (April 2025) when everything collapsed, cold glans, turtling and no response.

I started seeing urologists and Peyronie specialists because that's what I thought I had In June 2025, I tried out traction and vaccum device therapy as doctors suggested only very lightly it for 3 days consecutively. It caused another flare and collapsed, zero function, complete veno occlusion.

I saw a fibrosis specialize surgeon after that and we concluded deep trauma and fibrosis to both the tunica and corporal. Entire left side feels tough under the skin and right side 2/3 up feels the same. There are some soft moments in brief hours right now it might be soft but it's trending to total hardness overall. Erections stall at certain points and takes a while to push through sometimes, it acts as a cast that exist both inside and out.Ultrasounds shows no calcified plaques or fibrosis yet but is palatable to touch certain nodules and hardness. I'm afraid it'll eventually all harden into a rock despite the lifestyle change and medications.

As corporal fibrosis cases being extremely rare. Is been extremely difficult to navigate treatments and expectations. If there is anyone who can share their experiences even if peyronie, on how it progresses from injury till 18 months later and their therapies please help chime in. I feel so alone

I'm considering prp and stem cell as next step before considering something like implant

[Roman]

Hi I'm almost the same age 32 now and with a similar story. Because of the very slow french system I got diagnosed by ultrasound and MRI only 10 months after the injury.

Symptoms were pretty much same as yours. After injury I've had left side of my dick was unusually rigid and I had a palpable plaque during erection.

Ultrasound showed some micro calcifications. But no fibrosis detected on ultrasound and MRI with contrast. (Apparently it doesn't mean there isn't one )

I started treatment roughly 11 months after the injury. Shockwave, pentox, l carnitine, tadalafil 5mg daily

So far that's the 6 months of treatment. Rigidity on the left side in quite a large area is almost gone (feels much more just like a normal soft tissue). Pain is almost gone as well. But speaking of plaque it's still there and so far it's hard to tell for sure if it's smaller or not. At least it's not worse

Speaking of no point to live and no hope. I'm having these thoughts from time to time as well. But I kinda starting to think that in worse case scenario .... it maybe prothesis can be a solution. It's definitely not a sexual life we're all use to. But the good thing is that you can have rock hard erections like when you were teenager and actually not thinking about this problem anymore. I try to calm myself thinking this.

But actually since there are some small and very slow results from treatment I try to keep hope

Btw how long are you talking those meds ?

"There are some soft moments in brief hours right now it might be soft but it's trending to total hardness overall" btw was having exactly the same sensations for a year before I started treatment (rigidity on the left side around the plaque) For me it's almost completely gone right now and quite similar sensations in the plaque when flaccid while the plaque was always definitely harder than the surrounding tissues. So in the plaque sensations didn't change a lot so far

[alex_be]

Please, there is always hope ! I know it's difficult, but as long as you didn't test everything, there is always hope!

Have you been to a psychologist? That therapy helped me A LOT ! Really amazing!

Have you tried other kind of therapies ? Like the Wim Hof Method for example?

Please stay positive, even as difficult as it is.

Good luck!

[Mikel7]

You are not alone in your feelings as all of us men have experienced severe dread and anxiety with peyronies and you should realize that you will eventually come through this! It is no shame if you need to be placed on some anti anxiety meds for this and remember that you can stop them when your emotions settle down with this. Don't give up!!

[Florida]

I been taking these supplements and meds since  late May of 2025 this year so is been 5 months. Is hard to tell whether I'm healing correctly or not because erections are getting tougher to get not because of lack of blood flow but the fibrosis acts as a cast and restricts expansion and would sometimes stall and fail.

From August onwards the fibrosis have been hardening at an accelerated rate. I still have goggle state of softness and toughness during flaccid but the fibrosis seems to be very widespread.

I'm seeing 2 psychologists and still seeking urologists and stem cell. But the stem cell journey is leading me to believe even the most reputable places are not operating on full transparency when I ask the deep technical knowledge. I'm now in dilemma do I take a chance on stem cells treatment I'm not sure of and risk potential worsening from a botch job and poor engraftemnt with more trauma. OR keep taking my supplement stack and fasting and hope it gets better

The slope has been a downward decline no matter what I do, losing functionality seems to be the trend as fibrosis hardens. I don't know if this hardening or decline in functionality is non stop or will get better once chronic