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Author Topic: Adipose-Derived Stem Cell Research - ADSC's  (Read 1505 times)

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Crooked_Stick

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Adipose-Derived Stem Cell Research - ADSC's
« on: December 13, 2017, 01:59:32 PM »

This, according to my Uro, is the next major treatment being developed with trials starting in 2 years...

Some new research:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704342/

In summary, we had shown that ADSCs could inhibit the activation of tunical albuginea MFs, reduce the expression of collagen in MFs through TGF-β1-Smad signaling pathway, suppress the contraction of myofibroblasts by RhoA-ROCK signaling pathway. In the other hand, ADSCs could degrade collagen by paracrine or promoting MFs autocrine MMPs. Furthermore, ADSCs could induce apoptosis of MFs, though the detail molecular mechanism was confusing. These findings suggested that ADSCs attenuated the development of Peyronies Disease (Fig. 7). The anti-fibrotic ability of ADSCs will be considered in future treatment approach of Peyronies Disease.
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Born 1960, Diagnosed 2013
Initial 40 degree bend, 1" loss, Xiaflex 3 rds of 2 injections
Current 25 degree bend, no palpable plaque, 1/4" loss
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Re: Adipose-Derived Stem Cell Research - ADSC's
« Reply #1 on: December 16, 2017, 07:34:45 AM »

This, according to my Uro, is the next major treatment being developed with trials starting in 2 years...

Some new research:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704342/

In theory is this experimental treatment can somehow restore length or even slightly add length via remodeling of tunica?
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Drygedene

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Re: Adipose-Derived Stem Cell Research - ADSC's
« Reply #2 on: February 02, 2018, 02:49:52 AM »

I love the way the members have responded very well.
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Paolo

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Re: Adipose-Derived Stem Cell Research - ADSC's
« Reply #3 on: February 02, 2018, 03:37:46 AM »

Nice find and thanks  :)
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Whenever you find yourself on the side of the majority, it is time to pause and reflect.
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