Vitamin E

[Darren_SG]

Hi there,

I have been looking at some extra strength vitamin E oil which you apply direct to the plaque, anyone had any success with this? THoughts if it will work?

[Hawk]

Without surgery you could not apply it directly to the plaque, you can only apply it to the skin of your penis.  there is about as much chance of getting the vitamin E past the skin blood vessels, tissue known as Buck's Fascia, and into the tunica as there would be to rub it on your back and get it into our kidney.  It just is not going to happen.  Vitamin E does not just soak through skin and tissue like that.  

The massage will not hurt and could have some benefit but not because o the vitamin E.  

[George999]

AND our skin is there for a reason.  There are many things, like vitamin E oil, that we consider very healing.  But if you were to inject something like that directly into your blood stream, you would be very ill, if not very dead, in no time.  Our bodies simply don't work the way we often assume they do.  It is just not that simple.  That is way the uro doesn't just give you an injection of vitamin E into your penis and send you home to watch your Peyronie's problem fade away.  - George

[Amitr]

So where does it go once it's absorbed by the skin?

Is absorption there quantitatively worse than eating the same amount.. say 400IU?

[james1947]

amitr7

You have the answer two posts bellow yours
Posted by: Hawk
« on: March 11, 2013, 07:58:08 PM »

James

[Amitr]

Hi James,

Well that post hasn't exactly answered my questions. They were more like counter questions to that post itself.

1. Where does the oil/Vitamin go once it's absorbed, if not (at all?) into the corpii.

2. How does this absorption efficiency compare with that of oral consumption for its effect on the penis.

[NeoV]

I just posted a link on a different thread of a 2013 study on topic olive oil to fractured penises in rats.
Seems quite plausible to me, that at least olive oil has transdermal effects.

Weather or not vitamin E actually is causing the effects is unknown to me nor is it made clear in the study. I think it could certainly help, but weather or not you will notice any kinds of effects is impossible to tell at this point.

[NeoV]

Since I could not find this mentioned via search, I'd like to post it here. This recent study seems to show strong evidence for Vitamin E usage in Peyronies Disease, which I think is fascinating considering the doubt I, and many others have had or have regarding it. If this has been discussed before, please remove it and I apologize.

Efficacy of vitamin E in the conservative treatment of Peyronie's disease: legend or reality? A... - Abstract - Europe PubMed Central

Highlight: (In the Vitamin E group)... "the improvement of curvature occurred in 96.6% of the cases whereas in the control group B this occurred in 48.4%"

Both control group and group B used several different treatments including verapamil injections. Weather vitamin E alone (or with pentox, or in my case tranistat) would give this much benefit could be debatable, but I don't see why not, and I certainly think this makes a good enough case to take it along with your other treatments.

However, rather than make any kind of argument, I just wanted to post this for people in case they missed it or it had not been discussed here on the boards.

[james1947]

https://www.peyroniesforum.net/index.php/topic,3608.0.html

there is about as much chance of getting the vitamin E past the skin blood vessels, tissue known as Buck's Fascia, and into the tunica as there would be to rub it on your back and get it into our kidney.

James

[james1947]

there is about as much chance of getting the vitamin E past the skin blood vessels, tissue known as Buck's Fascia, and into the tunica as there would be to rub it on your back and get it into our kidney.

James

[Njnist]

While I agree with you James, I believe this study was using oral vitamin E with topical verapamil, not topical vitamin E.

[George999]

I used Vitamin E for several years and have always believed it to be helpful.  But it was nowhere near as helpful as ALC.  And ALC was nowhere near as helpful as Pentox.  So I think it is a matter of degrees.  Modern treatments are just so much better than Vitamin E.  That is the situation as I perceive it from past experience.

[Njnist]

ALC definitely helped me but I stopped taking it because I believed it was causing gerd for me. Anyone else having that effect from ALC? I'm currently taking pentox but the mental side effects (fog brain and such) are getting to me but it seems the worst at 3 tablets a day. I am going between 800 and 1200 mg a day and trying to tolerate that effect. No other side effects so far but that one is pretty significant  

[NeoV]

Thanks for the clarification. This study is a recent study on oral treatment, and the results are very impressive. I already know well what supplements seem to work from lurking on here for years, as well as having tried nearly all of them. I think I also remember having slight gerd from ALC, but it never was a problem for me. That's too bad, where you having it in liquid form or pill form? and did you have it with food? Maybe it's just not worth doing in your case if it is bothering you like you said.

[Njnist]

I was taking capsules. I started developing a cough and thought it might be related to gerd because of a few other symptoms. It could've been coincidental though but it seems to have improved slightly since I stopped taking it.  

[mmmm]

The same italian researchers published this article on 2012

Effectiveness of antioxidants (propolis, blueberry, vitamin E) associated with verapamil in the medical management of Peyronie's disease: a study of 151 cases

It was made with a larger sample and with five different drugs combinations. Only one of them didn't include Vitamin E and this is what they had to say regarding that matter:

However, the unsatisfactory results related to group 5 (without vitamin E) in many categories of results show that vitamin E probably plays a significant role in the treatment of Peyronie's disease (contrary to what is reported by Hauck and other authors) especially if combined with other active drugs. The data for improved erectile function in all groups (see Fig. 1) excluding group 5 (p = 0.010 chi-square test) suggest that vitamin E may play a role in this situation.

The evidence regarding Vitamin E is at least mixed. Perhaps it plays a role as a synergestic agent? Perhaps alone doesn't make much of a difference, but in a combined therapy could be helpful?

--------------------------------
Regarding ALC I had to stop taking it because it gave me neck pain and headaches. As if it made my muscles stiff. It appears to be rare to have side effects from this kind of supplements but it's always a possibility I guess

[MtnSurf]

ALC definitely helped me but I stopped taking it because I believed it was causing gerd for me. Anyone else having that effect from ALC? I'm currently taking pentox but the mental side effects (fog brain and such) are getting to me but it seems the worst at 3 tablets a day. I am going between 800 and 1200 mg a day and trying to tolerate that effect. No other side effects so far but that one is pretty significant

Njnist, I'm pretty sensitive to reflux/heartburn, but have not noticed any from taking ALC. Are you also taking cialis? Acid reflux & heartburn are well known side effects from daily cialis. I take 5 mg cialis before bed and noticed a return of my reflux after I stated taking them, so I'll usually take a heartburn relief tablet like tums or Gaviscon before bed as well.

Also, do you think the "brain fog" you mentioned could be due to the psychological stress peyronies brings with it and not from pentox? Peyronies is  A LOT to cope and deal with. Depression and elevated stress/anxiety can definitely effect your mental sharpness, especially over time. It seems mental anguish is very common with those who suffer from peyronies. I know it has been for me.

[Njnist]

I was pretty certain it was from ALC, but again I could be wrong. I started on Zantac 150 twice daily and it seems to have mostly resolved. Could be the Zantac helping and not stopping the ALC but who knows. I also stopped Fish Oil because that is known to cause GERD.

The brain fog was most definitely from the pentox. I could tell at about the 3-4 hour mark it really ramping up after consuming Pentox but since cutting to 400 twice daily it has improved significantly. I will ramp it back up to 3 a day in a short time now that I tolerate it better. At least that is the only side effect I have noticed! (that and being pain free!!). This stuff is amazing, my inflammation seems to have calmed way way down and the pain is all but gone now.  

[Jonbinspain]

Re ALC, I now take anywhere between 2-4g per day. At first, it caused me gastric problems; but after a time they went. I also take Vit E, Pentox 4x400g at the moment. My situation, along with traction, seems to be improving marginally.  What is bringing this perceived improvement, I don't know. I'm just battering this damn disease with everything I can practically use that is liable to help. If it works, I will neither know nor care what was largely responsible.

But, if you feel ALC is helping, try sticking with it for a while and see if your body adapts.

[MtnSurf]

I was pretty certain it was from ALC, but again I could be wrong. I started on Zantac 150 twice daily and it seems to have mostly resolved. Could be the Zantac helping and not stopping the ALC but who knows. I also stopped Fish Oil because that is known to cause GERD.

Njnist, you may want to try this lower mg fish oil (I take it 2 or 3 times per day). I tolerate it well and use to get heartburn from the higher dosage fish oil.

Amazon.com: Nordic Naturals - DHA Strawberry - 180ct: Health & Personal Care

Also it should be known that acid blockers and reducers can prevent your body from absorbing calcium and lead to bone, dental calcium deficiency over time. I've been dealing with reflux since i was a kid.  

[Njnist]

Yah that's part of the reason I went with an h2 blocker instead of a ppi but I'm sure it could still cause problems. Ill try and cut it out and see how I react  

[jackp]

OTC fish oil gave me heart burn and a fish taste in my mouth all the time. I quit taking it.

A couple of years ago my cardiologist wrote me a prescription of Lovaza 1GM 2 in the morning and 2 in the evening. No after taste or heart burn. I asked a pharmacist friend at church about Lovaza, she said it was the equivalent of taking 48 OTC capsules a day.

The one thing I did notice was after about 6 weeks I developed better feelings in my glans.

Jackp
http://jackp-penileimplant.blogspot.com  

[IhatePD]

You can get your Omega 3-6-9 form Udo's Oil. It tastes like sunflower seeds and you can find it in a vitamin shop store and others. It has the correct ratio of all three essential fatty acids without the fish taste.

[MtnSurf]

@IHATEPD,  Would you recommend the Udo's oil in capsule form or oil?

-thanks

[Old Man]

Note to all:

In the what is it worth department:  Over the past 50 plus years of having ED, Peyronies Disease and other men's health problems thousands of different types of vitamin E were taken day in and day out. To this day, vitamin E has never ever done anything toward even treating ED or Peyronies Disease. The final result of was a daily dose of indigestion and/or upset stomach along with diarrhea.

The above is just my 2 cents to weigh on on the vitamin E trip!!!

Old Man

[IhatePD]

MtnSurf I use the oil as you are supposed to take one tablespoon per 50 lbs. bodyweight each day. You have to take a lot of capsules to do that so I take two tablespoons each morning in my protein shake and then one and one-half tablespoons after dinner right from the spoon.

I am OK with the taste but my soon to be ex-wife (thank God!) couldn't stand the taste. I think it tastes like sunflower seeds which it is partly made from. I know that Tony Robbins is a big fan of Udo's oil as well.