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QuoteQuestion - Does the clamp result in new plaque / scars near the head of the penis?Answer - We haven't seen anything like that in any of our 5 studies we've done so far with Restorex (probably a combined 500 patients or more). In those studies, men used the device up to 9 months. In all of the studies, men self-reported findings, and we performed examinations as well. I have probably had several thousand patients use the device now, and I've never had one report findings like you're mentioning after use. I have had, however, many patients who have complained about plaques in that area (nearly all younger men in 20's/30's, most of whom didn't/don't have Peyronies Disease). Every time I've examined them / done ultrasounds, we've never confirmed a true plaque. It's nearly always just the normal anatomy in that area. In many cases, these were high anxiety patients (often with histories of anxiety/depress) who focused heavily on the penis and started noticing things that they hadn't noticed before. This is also common when men will come in with a new vein that they hadn't noticed before. So, based on all of this, I think there are a few possibilities:1 - It's very rare (i.e. happens in rare cases)2 - It's temporary and stops after discontinuing use (i.e. like the callouses you get on your hands when doing yardwork etc.)3 - The device clamp isn't being used correctly. The clamp isn't designed to clamp down on the tunica at all (it only clamps the head). I've seen several people who try to clamp the shaft as well as the head, but this isn't the correct way to use it. Also, it's designed to be used with a wrap around the head to help it stick and offset any direct force.4 - The suspected plaque is from thickening of the ligaments which attach the head to the corpora. Just like the callouses concept, as the penis is stretched, it's possible that the body strengthens the connections between the head and corpora. These would be expected to soften up over time.5 - The area doesn't truly have a plaque but is just being noticed more. Most people don't realize that this is where the corpora all comes together (distal areas of both cylinders + septum). When people self-examine this area (i.e. draw attention to it), they often feel like there is a plaque there (very common). But in reality, it's normal anatomy.