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Welcome to Dr. Landon Trost - Directly answering member questions in the "Medical Professionals" section below.
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Tamoxifeno

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Paul80

hello recently two urologists have sent me tamoxifen. Has anyone on the forum improved with this? or has anyone used it? or any opinion about it?
injury during sex in January 2022. note like a needle stick. result fibrosis nodule 7mm by 5mm oval. dorsal curvature 20 degrees, hourglass narrowing. currently cialis 5mg, pentox 400 once a day, and Ved therapy

Pfract

Hello. Did they recommend it to treat peyronies?
Penile fracture during sex, Portugal 2014 - [url=http://www.peyroniesforum.net/index.php/topic,11131.0.html]Penile Implant Forum -Tech info compilation and Index - Peyronies Society Forums[/url]

alexsan

Tamoxifen is for gynecomastia or breast cancer.How could they prescribe it for peyronie?
Immediate 40 degree right curve due to injury on 3rd June 2021
Uro diagnosed me with penile injury on 2nd September 2021
Curve came down to about 20-25degree with-massage and cialis daily,after that didnt change

Paul80

That's why I was asking, they sent it to me to see if it reduces the nodule, that's why I was asking if anyone knew about this. eii Pfract would you mind writing this to me privately trying to contact you
injury during sex in January 2022. note like a needle stick. result fibrosis nodule 7mm by 5mm oval. dorsal curvature 20 degrees, hourglass narrowing. currently cialis 5mg, pentox 400 once a day, and Ved therapy

Pfract

How Paul. What do you mean?  I am not sure I understand.
Penile fracture during sex, Portugal 2014 - [url=http://www.peyroniesforum.net/index.php/topic,11131.0.html]Penile Implant Forum -Tech info compilation and Index - Peyronies Society Forums[/url]

blex

Tamoxifen has been tried for Peyronie's with mixed results.
It was reported to reduce plaque and pain initially, but never could show results in controlled studies.

You can search about it here in the board, on Pubmed or Google.
36 years old, married
---
Symptoms since trauma in July 21:
First calcified nodule in septum near glans
Multiple calcified plaques developed on top
Pain (flaccid/erect), 75° upwards curvature, hourglassing
---
Nothing helped, looking for surgery now

Mikel7

Lump April 2020, age 61 , Dr Levine 6-26-20,
Dorsal Curve 11-1-20 , Peyronies
Vit E400mg, COQ10, ALCAR, Heat Therapy, Penimaster, Pentox, Cialis, Restorex
had SNHL 7-31-20 - Stopped all Meds because ototoxicity  Heat/traction/VED are working.

blex

@mikel7
What is this even supposed to mean?
Most supplements listed in your signature and recommended in the forum influence hormones in some way.

Personally, if it helped with peyronies - yes I'd gladly mess with my hormones any day.
The question is: Does it?
36 years old, married
---
Symptoms since trauma in July 21:
First calcified nodule in septum near glans
Multiple calcified plaques developed on top
Pain (flaccid/erect), 75° upwards curvature, hourglassing
---
Nothing helped, looking for surgery now

bentoboy

How do you know that those supplements affect hormones?
26 y. o. Peyronie since 2020: upward congenital curvature from the bottom - 20*; twist and curve to the left - 25*; two visible dents on the left side; multiple plaques everywhere; no pain

Vitamins; Tadafil; traction/bending; VED - nothing worked

blex

Examples that some might affect hormones:

QuoteCoQ10, vitamin E, and cosupplementation led to decreased serum total testosterone levels
https://academic.oup.com/jcem/article/104/2/319/5091457?login=false

QuoteAt rest oral L-arginine ingestion will enhance the growth hormone response
https://pubmed.ncbi.nlm.nih.gov/18090659/

Remember that, while this forum is a useful place to exchange experiences, please don't take my or others posts as gospel.
Linked research (including mine) might be outdated, biased, weak, unfitting or simply wrong.

Tamoxifen has been used against peyronie's, so it's not like his doctor pulled this from nowhere, i.e.:

QuoteOral therapies most commonly employed include tocopherol (vitamin E) and paraaminobenzoate (Potaba), with colchicine, tamoxifen, propoleum, and acetyl-L-carnitine being used less often.
https://pubmed.ncbi.nlm.nih.gov/18974422/

I personally don't believe it is useful, but DYOR!
36 years old, married
---
Symptoms since trauma in July 21:
First calcified nodule in septum near glans
Multiple calcified plaques developed on top
Pain (flaccid/erect), 75° upwards curvature, hourglassing
---
Nothing helped, looking for surgery now

Paul80

Pfract I am trying to contact you by private message or email. how do i do it? you do not receive my messages?
injury during sex in January 2022. note like a needle stick. result fibrosis nodule 7mm by 5mm oval. dorsal curvature 20 degrees, hourglass narrowing. currently cialis 5mg, pentox 400 once a day, and Ved therapy