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Author Topic: Verapamil and DMSO delivery  (Read 199 times)

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Godisreal

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Verapamil and DMSO delivery
« on: November 11, 2019, 02:39:28 PM »

Does anybody have experience combining these two? And does anybody know if there are risks with trying transdermal techniques on my dick? I would really like to try it out, possibly with some oils hoppin in to the mix as well.
Anyway, please share with a fellow member if you have any experience or thoughts regarding Verapamil and DMSO put together...
God bless you
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Youngster with Peyronie’s and high erection angle, peyronies onset in September 2019.
Mild/Moderate dorsal curve, occurred overnight after re-injury. Flaccid narrowing. Hard flaccid. Flaccid pain/discomfort

samsung

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Re: Verapamil and DMSO delivery
« Reply #1 on: November 11, 2019, 04:49:12 PM »

I don't, but just as an aside, curious to see what people say here. I am going to have some made at a compounding pharmacy and include Pentox and vit. E along with verapamil. They were familiar with peyronie's and they had done DMSO with verapamil before. PM me if you want the name of the pharmacy.
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44 y.o. Single. Onset of symptoms (pain-stinging like a wasp) @ 6/2018. No sudden injury. Curve developed slowly. 40 deg. dorsal. Hourglassing. Torsion to left flaccid. 2 rounds xiaflex. Restorex, DMSO+, heat, arginine, cialis, lipoic acid, vit. K2

buzzin2

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Re: Verapamil and DMSO delivery
« Reply #2 on: November 30, 2019, 12:46:25 PM »

can you just make the decision yourself to have something made at a compounding pharmacy with stuff like pentox in it? like, would i be able to just talk to a compounding pharmacy and tell them what i want and have it made?
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TonySa

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Re: Verapamil and DMSO delivery
« Reply #3 on: November 30, 2019, 02:29:02 PM »

A doc can prescribe it and then a compounding pharmacy  mixes it for you.  You’d need to know if pentox would be therapeutic as a local agent rather than systemic effect as oral.
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PxD 2 yrs, failed all tx. 9/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3rte

samsung

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Re: Verapamil and DMSO delivery
« Reply #4 on: November 30, 2019, 02:43:39 PM »

No. You would need a prescription.

Doctor said it would have minimal systemic absorption with liposomal base but would hit system more if DMSO used.
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44 y.o. Single. Onset of symptoms (pain-stinging like a wasp) @ 6/2018. No sudden injury. Curve developed slowly. 40 deg. dorsal. Hourglassing. Torsion to left flaccid. 2 rounds xiaflex. Restorex, DMSO+, heat, arginine, cialis, lipoic acid, vit. K2

P47D

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Re: Verapamil and DMSO delivery
« Reply #5 on: December 02, 2019, 01:06:30 AM »

Hi Godisreal,
Couple of thoughts related to this from my earlier research when my Peyronie's was just getting started.  First about the DMSO - this substance has only been tested and found to have tangible benefits on a few specific issues and it comes with  some warnings.  Also, DMSO can be obtained but its purity may vary from 10% to 90% depending on the manufacturer!?!?  It apparently does help make some medicines "get into the skin better" with its transdermal properties...however it will also take anything else that is present along with it so keeping your hands/penis/underwear (everything!) very clean is important.  You can get DMSO at health food stores, but I don't know what level of purity or quality it will be...is it medical grade???  It has risk warnings for some things like diabetes, kidney and liver problems too.  It appears to be more adept at directly skin related issues and since a Peyronie's plaque is much deeper it may not actually carry the Verapamil into the plaque itself.  My urologist did try Verapamil with me and the best technique is an injection directly into the plaque itself.  The side effects from Verapamil are very mild compared to Xiaflex, and Verapamil was quite inexpensive - only $20 per treatment!  I picked up a vial of the liquid at the pharmacy, took it to the Dr, they administer it - simple!  I would recommend only working with treatment options directly with your fully qualified urologist who has experience with Peyronie's.  A compounding pharmacy may be willing to mix up a batch of whatever you want...but that may not be a good idea unless it has the approval and advice of your urologist behind it. 
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Trauma induced 74 degree vertical dorsal curve in OCT 1916 - after 3 years, success with plication.

TonySa

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Re: Verapamil and DMSO delivery
« Reply #6 on: December 02, 2019, 03:24:02 PM »

Don’t keep DMSO in a plastic bottle as it can absorb the toxic compounds and deliver to your penis.  Always dilute per instructions.
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PxD 2 yrs, failed all tx. 9/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3rte

buzzin2

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Re: Verapamil and DMSO delivery
« Reply #7 on: December 02, 2019, 05:14:17 PM »

have you guys used dmso though? im going to order some, it seems totally safe if used with common sense
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P47D

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Re: Verapamil and DMSO delivery
« Reply #8 on: December 02, 2019, 05:57:52 PM »

Hi buzzin2,
Personally?  Don't bother.  While I was going through all the hoo-ya when the Peyronie's first occurred, transdermal therapy was one of the things I looked at quite closely.  From all my research and bouncing my thoughts off of valid, reputable medical information there is not any sense to me that any form of transdermal therapy is actually effective.  Now, here is the confusing part: you can find many "anecdotal" reports on line about various treatments using transdermal applications...but none of them have passed the wicket to be regarded in major medical research venues.  My impression is that some patients may do several things simultaneously, not knowing what actually worked, and attribute certain results to a particular thing.  The vast information database available on-line from reputable urologists and nationally accepted medical schools/universities do not seem to gravitate to any transdermal treatments.  Peyronie's appears to be a tricky thing since the actual plaque can be located in many different places, can be formed from either congenital genes or specific trauma events, and the plaque can be very robust and hard (calcified) or soft and hard to feel (non-palpable).  All that said, find a reputable urologist who either has experience with treatment of Peyronie's or is in a Urology Group with others who do...get their advice for your particular/specific condition.  You may have certain aspects that lend towards medically sound and accepted treatments.  Guessing with homeopathic or other treatments is just that...a guess.

Best of luck to you bro...this condition is terrible...but can be remedied one way or another.

Cheers,
-P47D
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Trauma induced 74 degree vertical dorsal curve in OCT 1916 - after 3 years, success with plication.
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