Complete Scam Article

[Hontas]

https://www.ncbi.nlm.nih.gov/pubmed/12441945

It is written in the article that that Mulhall scum is funded by major Erectile Dysfunction drug manufacturers, they tried to undermine the effectiveness of Verapamil and Steroid cream treatment on penis. This crap is F^@$!ng disgusting. There are at least 100s of urologists trying to undermine successful treatments. I am reading the book of Levine right now(Peyronie's Disease- A guide to clinical management) and there are so many promising treatments that got burned down because they literally don't want any type of treatment to be seen as successful. Verapamil and steroidal creams, tamoxifen, everything. They literally make up stupid research that consists of people only in chronic phase, to eliminate the effectiveness of the drug from previous research. I honestly think these people should be sent to super max prisons for life.

Just look at this comment over the article above:
https://www.ncbi.nlm.nih.gov/pubmed/15821608

They literally totally lied on the first article and it even got a response due to complete sheer utterly stupid logic behind it. It didn't even have proper methods or anything, they just put it on a respectable scientific journal to make it seem credible.

[Pfract]

Care to back up those claims?  

[Hontas]

  How about you read the second link that i posted that claims that the article is totally bullshiting in a professional manner?

[skunkworks]

https://sci-hub.tw/10.1097/01.ju.0000158664.00107.07

[Hontas]

Thanks a lot skunkworks, I didn't know if we were able to post that here so i wasn't able to.

[samsung]

Mulhall pretty much known as an incompetent fraud, right?

[skunkworks]

Thing is either way we are taking something on faith, I have no idea if the numbers in that reader letter are accurate or not. If they are, it does not paint Mulhall in a good light.

Certainly the method used in the study to disprove is not at all similar to the method used in past Verapamil studies, which does suggest some dishonesty on Mulhall's part from the get go.

[Hontas]

skunkworks,

i am fairly certain that books and especially the book written by Levine is a much better source than articles in general. I normally google search but maybe i should change where i search academic information... Do you guys have another recommendation on where to read peyronie's related or other disease related articles other than books, google scholar and search?

Also from what i understand the guy literally didn't include the fact that verapamil is excreted only 3-4% from urine, and that meant 960 mg daily dose of verapamil in serum according to the comment. Thats twice the max dose of normal verapamil. Also not to mention that the stratum corneum of the shaft is so thin that it permeates more than half of corticosteroids dosage according to an old research which probably means other agents would penetrate almost as well.

[melting]

The key to most transdermal applications is anyway a high frequency application.
Some will go back into the blood stream and some wont make it to the site of the plaque. Applying often enough some will go to the plaque. At best saturating the tissue via regular applications. Just simple logic