Stem Cells & Adult stem cell injections for Peyronie's

[rd]

egghead, I had mine done in California but they have also started branching out and have a network of doctors all over the us that I believe use the same procedure. My reason for doing in Cali was because Dr. Landers is a Urologist which I don't think the other doctors in the network are. Also when I went to have it done they didn't not have a network of doctors.

[yyy]

This morning I had a prp injection done.
The goal is to improve healing and vascularization of the zone (pretty bad at the moment)
Speak soon  

[rellisacct]

Hey guys, quick update along with YYY...

The doctor I am seeing had some sort of emergency surgery so the next appointment and series of injections got pushed back to next week. I'll update soon...

[funnyfarm]

Thanks for the updates guys, we are eager to hear from you soon again.

[Amitr]

I just read about stem cell therapy online and I thought I'd share it here... but whoa.. there's loads of info about it here already.

So I have a few questions:
1. Since this seems such a promising new avenue (seems better than Xiaflex for one), shouldn't stem cells be popularized as a possible solution much more here.

2. We're more of a resource for clinical trials right here, so is there any way to get the medical community more aware of this forum. The knowledge of such a large readymade user base might be encouraging for an underreported disease and emphasize the need and viability of research.

[funnyfarm]

It is more of a political/economic issue.  Xiaflex has billions of dollars behind it, while Stem Cell just has a few clinics with innovative doctors who are willing to go beyond conventional standards.  In other words even if stem cell works great, there are no big corporations backing it, and no huge windfall profits for investors and governments.  

SS is more invasive, time consuming, and not patentable so I doubt it will be widely adopted even if it is very effective as it is less profitable.  

Hopefully there will continue to be enough people backing stem cell though to make it more widespread.  

[koolx]

funnyfarm,

thats not entirely true. big corps like merck, bristol-myers squibb, etc. are actively getting into stem cells for patent and licensing purposes. and they make it an effort to prevent good stem cell treatments from making it to the public. unless it produces a profit for them.  

[MattFoley]

Guys,

Stem Cells are potentially the most devastating resources that ever existed to the pharmaceutical companies because of the massive potential to heal and improve any medical condition.

The last thing pfizer or any of the other big pharma's want is to see their profit margins drop because stem cells are actually curing the disorder rather than deal with the symptoms.

I found a doctor in the area who does the stem cell procedure but the cost is $4,500 so at this time I can't afford it but I will be working towards getting enough money together to make it happen.

[rellisacct]

I agree with MattFoley. Big pharma doesn't care about people's health, just the bottom line.

Can you disclose the name of that doctor Matt and where he is located?

Also, I'm going back to Wake Forest Tuesday for my second round of injections of PRP. I'll give an update ASAP.

[funnyfarm]

What is really novel about SS is that it gets to the root cause of the problem by inducing your body to heal itself.  Most pharmaceuticals on the other hand treat the symptoms, not the disease, so you never really get better and become a lifelong customer.  Koolx, I think it is quite plausible big pharma will try to develop and license SS.  This is not with the intention of helping patients, but rather to control the intellectual property, ensuring it is kept out of the mainstream, protecting conventional drug sales.  

I know there are herbals that are effective for cancer treatment, but you can not use them in the US because the FDA was convinced by these corporations they are not safe (based on studies where rats were given doses 1000' s of time higher than the therapeutic range).  So Americans are forced to rely on expensive chemo and radiation treatments alone, while enduring all of the barbaric side effects.  

[inkhorn]

Very interesting thread. I agree that it may not happen to most of us in our lifetime, but the research on stem cells is golden. I believe in it enough to pay to have my four grandsons cord blood collected at the time of their births. If this cussed disease has any genetic connection they will be set up for victory! Regards Inkhorn  

[MattFoley]

rellisacct,

The doctor is located in southern California.

Here's the doctor's info:

Elliot Lander, M.D., F.A.C.S.
Medical Director
California Stem Cell Treatment Center

website: http://www.landerurology.com/index.html


Here's the website to the network of doctors across the country:

http://www.stemcellrevolution.com/


Good luck to you.

[koolx]

hey Matt,

do u have erecrtile dysfunction or peyronies?

[rellisacct]

Hey All,

Just thought I would give you a quick update from the doctors office.

This time they have taken double the amount of blood which equals double the amount of PRP. I'm thinking that they will inject all along the left corporal tissue as this is where the girth loss is.

More updates coming...

[CTS]

Hi all,

I talked to Dr. Elliot Lander at the California Stem Cell Treatment Center.

He aid he previously treated 12 patients with stem cells and  PRP.  In 50% of patients, he found no improvement and in the other 50% of patients he had a small  improvement. This was not good enough so he has moved on to try new proceedures.

He has now modified the proceedure to use shock wave therarpy and stem cells (and no PRP). You go for three sessions over 5 days.
- Day one, shock wave therapy.
- Day three, harvest adipose stem cells, shock wave therapy and inject stem cells.
- Day five, shock wave therapy

According to Dr. Lander, the shock wave therapy will be done all over your penis with focused treatment on the plague.  The stem cells will be injected into numerous locations in the plague.  The stem cells will hopefully cause healthy tissue replace the tissue damaged by the injections and shock wave therapy.  The shock wave therapy excite/wake up the stem cells.  Since your penis is basically a big blood vessel, the stem cells will start to move away from your penis in about two days and go to lymph nodes, etc. until they are needed again. He claims significantly better results with the three patients treated so far and just treated a forth patient with the new proceedure. The procedure costs $7,500. He admits it is experimental and cannot promise anything - of course. He thinks my Peyronies Disease is still somewhat active since I am still feeling pain, and that the stem cells may be more effective - and are less effective once the Peyronies Disease is in the chronic phase.

About me, my Peyronies Disease is now mild compared to many of others in this forum. My conditon started in summer of 2010 (six months after I got separated - talk about timing) where I initially could not even maintain an erection and then it improved somewhat to the current situation.
- current age is 44 years old
- some pain still on the left side
- only a 5 to 10 degree curve and 5 degree twist/rotation when erect
- lost about 1/2" in length and some girth
- erections at 80% of the past
         - I need fairly constant stimulation to stay erect
         - I can still loose one easily but that probably more perfance anxiety than anything
- talk the following every day
         - prescription grade anti-inflammatory to keep pain away
         - daily dose Cialis
         - pentox

My girlfriend says she is very satisfied with our sex life.  I think it is really more about me and the initial shock that has me thinking about the proceedure.

I could go for the Xiaflex treatment with my regular urologist in September 2013.  I wonder if I do the stem cell / shock wave or the Xiaflex?

Any suggestions on how I should proceed?

Thanks!

[funnyfarm]

Thank you for the update.  Dr Lander has some great credentials.  I see he is chief of urology at one hospital and chief of surgery at another, and also was a urology professor.   I am curious if he discussed any other Peyronies Disease treatment with you that might help in addition to SS/shockwave ?  And did you actually meet with him or just call, in other words are you a patient of his ?

[CTS]

Hi Funnyfarm

We birefly discussed Xiaflex where he stated the goal of Xiaflex is to break down the scar (but it also breaks down healthy) tissue and grows back with normal scar tissue as oppose to excessive scar tissue as in Peyronies Disease.  He said no to do the Xiaflex and stem cells together. He pretty much did not have much to say about anything else.  He said the Pentox and Cialis do not help much...

He said he has seen many Peyronies Disease patients and can identifty plagues so he can easily target them for treatment.

CTS

[MattFoley]

hey Matt,

do u have erecrtile dysfunction or peyronies?

koolx:

I have ED as a result of the Peyronie's. The blood flows into my penis but because of the venous leakage, it won't stay in.

[koolx]

Matt,

what treatment options are u considering?

[MattFoley]

Dr. Lue has me on VED therapy and as well as Pentox.

If I had the $4,500, I would definitely do the stem cell treatment with the platelet rich plasma therapy added to it.

I've been doing periodic traction and I'm also on testosterone replacement therapy.

There are other things I'm doing as well. I talk about it here: https://www.peyroniesforum.net/index.php/topic,3052.msg47106.html#msg47106

[yyy]

Quick update 40 days after my last PRP injection

Erections are definitively improved, finally I can get a full erection when I need to get it, without meds of course.

I don't know if this is a permanent situation or just a temporary one, hope the former.

My Bend has not improved at all, libido has increased a little bit but not so much

I will certainly repeat the treatment, maybe together with my second stem cell

[Lollaro]

yyy how much is reduced the plaque?

[yyy]

I believe it has not decreased at all or very little

[koolx]

yyy,

how long after getting PRP did u notice that u can get full erections?

[yyy]

after about 20-30 days, hope this will be permanent

[Lollaro]

How do you to say that it's not diminished if you have a full erection? YYY

[Amitr]

What is really novel about SS is that it gets to the root cause of the problem by inducing your body to heal itself.  Most pharmaceuticals on the other hand treat the symptoms, not the disease, so you never really get better and become a lifelong customer.  Koolx, I think it is quite plausible big pharma will try to develop and license SS.  This is not with the intention of helping patients, but rather to control the intellectual property, ensuring it is kept out of the mainstream, protecting conventional drug sales.  

So true. I just want stem cells to help me get back my life. The pharma industry should be tried for its crimes against humanity.

[koolx]

yyy,

did the doctor advise u not to have sex for a week after he injected PRP?

[yyy]

no... but I think it's just a sort of precaution in order to avoid any kind of injury during that healing period.

[rellisacct]

YYY,

Based on what my doctor told me when getting the PRP (and some logical deductive reasoning), we should try to limit as much as possible the erections that we get for atleast a week. If there's a lot of blood flow after the injections, then it will wash the PRP out before it has a chance to settle and start signaling tissue to rebuild. This may be the same with stem cells too, but I know definitely for PRP.

Quick update: It has been 2 weeks since my last series of PRP injections and along with 5mg daily Cialis, erections are become rock hard again about 40% of the time. This is absolutely amazing as I was at the point where I would have 0% rock hard erections, ever. The main issue that I have left is the girth shrinkage due to the scarring and I've lost about 1/2 inch in length, but there is progress being made. There is still a long road to travel, however.

[funnyfarm]

It is great to see you are making this fantastic progress !

[koolx]

rellisacct,

i hope u received the links i sent u.. and that thryll give u some info to work with. if u need more info, let me know.

[rellisacct]

Hey koolx,

I looked through them and I'm extremely interested in the ACell one that you sent me. Have you ever seen the picture of where they regrew the soldier's leg muscle after half of it had been blown off? It is nothing less than phenomenal. If they can regrow fingertips and that much leg muscle, then our issue should be able to be improved.  

[james1947]

You are right rellisacct!!!
The difference is that while the regrow of the blown off muscle of the soldier it makes big waves and fame on the TV and other media.
Big advertisement!!!
Growing back some part of a penis? No one will talk about it except if it was cut by someone girlfriend or wife.

James

[rellisacct]

Yes, unfortunately you are correct James. It seems that no matter what treatments they start coming out with, we always come full circle to the original issue which is lack of care/funding.

[koolx]

hey, rellisacct..

i couldve sworn that i posted links here yesterday to the company making Acell and to the doc responsible for creating it. it may have been a computer error. anyway, here are the links. the doc's name is albert melman, btw:

this is dr. albert melman's contact info and website:
http://www.drarnoldmelman.com/contact-us/

the company founded by dr. melman that supports maxi-k:
Ion Channel - Gene Transfer Therapy

recently, i emailed dr. melman and got back this reply:
"I wish I could help you. We need to raise to capital to move ahead with the ED trial. Keep checking our website when that occurs it will be listed there and on clinical trials.gov"

my thought on this is, i understand that trials are expensive. sometimes on a corp level. but, given that this is a M-A-J-O-R breakthrough therapy, why arent private investors, companies or med universities jumping immediately at the chance of investing in this therapy with potential future dividends? something doesnt smell right with his reply, IMHO.

[james1947]

Koolx

I was not jumping to conclusions regarding

private investors, companies or med universities

not joining the project. It may be again not enough fame and not enough future money because the treatment will take long time to be approved.
We had sen other researches going this way (like stem cells).
Surprising me that Dr. Melman didn't propose you the treatment for a fee. Maybe if you had an appointment with him he was ready to make the treatment.

James

[Lollaro]

I hope that they find a cure that resolve the peyronies desease to 100%..

Many like me are young...and they hope in a definitive cure...
Unfortunately, the disease is not widespread and there are many researchs for lack of founds

[koolx]

lollaro,

autologuos stem cell and prp therapies seem to be doing an excellent job so far in reducing peyronies.. look into these treatment options but make sure that u find a reputable clinic.  

[Craig]

Do autologuous stem cell and PRP therapies work for those in the chronic phase? I know Xiaflex disolves actual scar tissue, giving people like me in the chronic phase hope.  

[rellisacct]

Craig,

I've had this crap for 11 years so it's pretty safe to say that there are calcified plaques. The PRP has helped me to at least get an erection again, but I don't think that its actually dissolved any of the plaque, maybe just re-shaped it. I'm still at the point however that if future PRP & Stem Cell injections don't loosen the scarring, then an implant will be the only option. The erections are still just not ridgid enough for prolonged sex. I've gone too long now without satisfying erections and can't wait for the rest of my life on "hopeful" remedies.

The reason I say this is that PRP won't be a "cure", but it might be helpful for people who have less scarring in their penis than I do (a single location rather than all over).

[jackp]

ewllisacct

The erections are still just not rigid enough for prolonged sex. I've gone too long now without satisfying erections and can't wait for the rest of my life on "hopeful" remedies.

Some who just glance at my story think I went straight to an implant. I also waited about 2 years after an implant was suggested before I considered it.  Kept trying everything possible short of an implant. My implant was almost 5 years ago. I wish I had it years earlier. You talk about satisfying erections an implant will give you that and more. I'm almost 71 now and within 30 seconds I can have an erection that sticks straight out, last as long as I or my wife wants, as many times a month as we want. NO I was wrong my wife and I don't just have sex, we make love! The feelings of making love to my beautiful green eyed wife are amazing.

If you have any questions about implants just send me a PM or email. I have some information you might like to see.

Jackp
http://jackp-penileimplant.blogspot.com

[rellisacct]

Thanks Jack,

I'm becoming more and more convinced that an implant is the correct option for me, but I guess for my own personal satisfaction I want to be able to say that I exhausted every other option available before going forward with it. My decision would be much easier if I couldn't an erection at all, but the erections I get are not good enough for sex so I guess it's just as bad as not having one.

I am planning on going to Dr. Milam around October for an initial consultation as you and a few others have spoken highly of him. But before I have surgery, I am going to go back on a VED protocol for 2-3 months and at least try the stem cell injections. Who knows, they may just work. If not, then there will atleast be finality to my sex life vs living in limbo all the time.  

[damian]

There is another thread about implants. I'm always thinking there are news about stem cells, everytime I see somebody posted here.

[rellisacct]

Yes Ushtipack, usually it is. The implant was a "one off" item. I was simply stating that PRP most likely won't cure anybody, but can definitely help if the plaque/scarring is localized. Additionally, I said that I will be getting stem cell injections when I can get time off of work to get it done. Both are relevant to the topic at hand.  

[Derick]

So, does the stem cell therapy do any good for venous leakage? Does anyone have any experience with it helping venous leakage and/or Peyronie's? ... and what would preclude a number of us to form our own 'group' for treatment with the stem cells.. (50... 100?)  

[rellisacct]

Hey riladojr,

I see from a previous post that you are in SC. I go to Dr. Terlecki in Winston-Salem which is about an hour north of Charlotte (where I currently live). He's good and I'm positive that he'll be able to help you.

Also, I think that the PRP has helped some with venous leakage because prior to receiving injections I couldn't even keep an erection. Now, I don't have as much trouble keeping it up, but it's just not usually a rigid erection due to scarring. What exactly are you recommending when you ask about a number of us forming our own "group"?  

[koolx]

rellisacct,

hey rellisacct.. how u doing? i got something that may help your particular situation and riladojr's. i came across info info on a dr. hsu. i think i suggested it to u before but i dont remember. his surgeries from what i've read have helped a lot of ED sufferers with venous leak and with "filling" the girth of their erections. u may want to take a look:

ED-Forum.com • Information

[rellisacct]

Hey guys, I just wanted to give a quick update on progress from my most recent PRP injections.

I had 2 injections Tuesday of last week at the base of the penis on the left side. This is where the bottleneck has been for 11 years and where there is calcified tunica on the top which gives an indention on the top of the penis. It appears that after 5 total injections so far, all in the left corporal tissue, the PRP has formed a matrix and is linking up blood vessels where scar tissue had taken over. I can now at least get an erection suitable for sex it appears. I think that the PRP is regenerating the corpus Cavernosum in the penis by increasing blood vessels and smooth muscle, however, the tunica is scarred to the point where it's not letting the tissue expand to its pre-injury girth. I have increased about 1/4 inch in girth from injections alone, which I'm pumped about. It may not seem like a lot, but for me that's a major victory.

Considering where I was just 6 months ago to now, I have to say that I'm cautiously optimistic about the future for the first time in years. I have a few more PRP injections lined up and will update as things progress. I do want to add that this is not a cure by any stretch of the imagination and things will never be close to where they were pre-injury, but God willing I'll be able to at least feel human again.

[koolx]

found this article, link below.. we're getting there, people:

Scientists create reprogrammable mouse in stem cell breakthrough, opening a new way to regenerate failing tissues in patients with diseases ranging from heart failure to diabetes | Bamboo Innovator