Are needles good for plaque or not?

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Anbil

I was reading a lot of studies about injections and in the ones using a control many urologists commented how the needle itself puncturing the scar tissue resulted in improvements.

However this conflicts with first hand accounts from many members here who report injections worsened or caused new plaques.

This also conflicts with the idea that trimix and other ED injections can lead to peyronies.


How can this both these things be true? How can the urologists say needles can be good for the plaque.
Onset of pain in March 2021
Progressed to loss of girth to dent under the glans left side

Been doing daily heat,traction,pentox,ved,cialis since initial onset of pain

Currently still experiencing pain and dent unchanged

PeyroniKirai

Hi Anbil,
Thanks for raising this; it's really a key question.  The simple answer is, if needles worked then all of us would already have been cured and there would be no need for this forum any more.  In my view - and I'm not a urologist nor a researcher - there is no injection that definitely fixes Peyronie's Disease.  We are still in the experimental stage.  Some men report improvement from injections, and some report absolute disaster.
 It's tempting to imagine that there is one little lump of bad stuff somewhere in the penis that is causing Peyronies Disease, and that if you could just inject the right chemical into it, it would go away.  In fact there isn't much in the human body that works like that.  Also, the tunica and the surrounding anatomy are very intricate, so a needle badly placed could easily do much more damage than good.    
 This is a vexing and baffling disease, so research and innovation are welcome, but before you go accepting injections from a doctor, I would suggest you question him very thoroughly.
- what exactly is the drug or the chemical you propose to inject?
- how precisely will it work?  Will it dissolve or soften plaque through a chemical action?  Will it trigger some reaction in the body that will reduce or remove the plaque?  Is there some other mechanism?
- what is your proof that this will work?  Have you got a list of success cases that you can quote statistics on - something like "X% of patients saw Y% improvement after Z number of injections"?   All good doctors keep meticulous records of the treatments they gave their patients and how the patients responded.  A good doctor will be able to quote those statistics to you.
- what are the worst potential consequences if the therapy fails?  What percentage of your patients experienced each of these consequences?

If your doctor can't tell you all these answers, don't let him anywhere near your penis with his needles!

Other forum members should chime in here with their experience, but my own view is that injections are all still extremely experimental and should only be approached on that basis.  If you have a severe case of Peyronie's and you are considering an implant, you might try injections first.  But if you're living with your Peyronie's and it's not getting worse, I would avoid puncturing the penis in any way.
Age 64, Peyronie's history 4 years, left side hourglass, 20-degree bend to left, no ED