Thank you so much! I hope it works.

I talked to the researcher doctor and he said that we hope to launch the antifibrotic drug on the market in the next 2 years. This drug is very important for Fibrosis diseases and there is also peyronie in these diseases. It not only stops the disease but also reverses the established plaques

I already pm you for the requirements.

I just ordered a bunch of supplements listed in this paper (https://jmedicalcasereports.biomedcentral.com/.../s13256...), in which several subjects experienced full remission within several years.

The supplements are:
Ginkgo Balboa
Diclofenac Gel
Coenzyme Q10
L Cirtrulline
Vitamin E
L Carnitine
Bilberry Extract
Propolis
Silymarin Milk Thistle Extraction

Does anyone have any experience with these products? Thanks for any insight!

You have my full support, I love your honesty about your Implant process.

So photos uploaded in sub-board Before and After Photos of Penile Surgery - Warning, Explicit Photos

I will also answer some questions in my message box here:

1. You don't have to undergo circumcision, but if your foreskin is tight, it may be necessary, the doctor will decide...
2. Surgery scar->I will also upload photo, but it is ok, it is barely visible, that shouldn't be your deciding factor.

I have never heard that VED is dangerous in combination with Tadalafil.

I guess what the urologist is getting at is that Tadalafil might not be a cure to Peyronies Disease on its own but it will most likely not make it worse. In fact, most research show that increased blod flow might contribute to prevent the condition from worsening.

One doc at one point warned me of Tadalafil because there is a miniscule chance of it causing priapism, which would indeed put you in the hospital. All other doctors since then has completely discarded this opinion, so that might also be what your doc was getting at.

I'd say VED, Tadalafil and any kind of antioxidants is a cost effective and non-invasive way of trying to stabilise your condition.

Hope that helps.

After having to wait almost 4 months for my appointment, I finally saw a urologist yesterday.

I described my problem, mentioning that I'd learned about the condition from this site---and he was instantly very dismissive of it as a source of information ("Who sponsors them???").  I mentioned that I'd had my family doctor prescribe me tadalafil to help prevent fibrotic formation, but the urologist was almost entirely dismissive of that, saying there was no evidence that something like tadalafil could help with Peyronie's.  I mentioned seeing peer-reviewed studies on this site, but he was entirely dismissive, saying they were a matter of interpretation, and that a site like WebMD is better for providing info.

He physically examined my penis and detected a knot under the glans, and a bit of a ridge a little further down.  So he prescribed me 400mg pentoxifylline 2x daily, and said that a third of the time, a problem like mine goes away, a third of the time it stays the same, and a third of the time it gets worse---and there's no way to tell which it will be.  I'm scheduled to see him again in 6 months for a check-up.

He did seem to think that using my vacuum device (which I bought awhile ago but never used) could help, since my issue is an indentation that it might help fill out (vs. a pronounced curvature, which he didn't think a vacuum device would help). 

So now I'm wondering if he was correct about tadalafil not helping prevent/dissolve scar tissue, and whether only 2 daily does of pentoxifylline is enough, since I see many people being prescribed 3x daily.  Seeing how dismissive he was of the tadalafil as helping prevent bad tissue formation, maybe he's just not taking treatments seriously enough and should have prescribed me 3x daily?  Should I try to contact him and push to be bumped up to 3x daily?

After 4 months of waiting, my appointment with the urologist finally arrived yesterday.

He said that a VED could help fill out my indentation, but that VEDs probably wouldn't help guys who have curvature problems.  He also said to avoid tadalafil in combination with the VED, or else I'll "end up in the hospital."

But being on 2.5mg daily tadalafil and using a VED isn't dangerous as long as one follows the VED protocol, right?  I don't remember seeing anyone here warn against the combination.

This urologist was also totally dismissive of tadalafil as helping prevent fibrotic tissue formation, so I'm not sure how seriously to take everything he said.  (He also was very skeptical & dismissive of this site, taking vitamins, etc., but I didn't feel like arguing.)

After having to wait almost 4 months for my appointment, I finally saw a urologist yesterday.

I mentioned that I'd had my family doctor prescribe me tadalafil to help prevent fibrotic formation, but the urologist was almost entirely dismissive of that, saying there was no evidence that something like tadalafil could help with Peyronie's.  I mentioned seeing peer-reviewed studies on this site, but he was entirely dismissive of those, saying they were a matter of interpretation, and that a site like WebMD is better for providing info than a site like this (which he was extremely suspicious & dismissive of).

But he did prescribe me 400mg pentoxifylline 2x daily, and said that a third of the time, a problem like mine goes away, a third of the time it stays the same, and a third of the time it gets worse---and there's no way to tell which it will be.  He scheduled me to come back in 6 months to see how it goes.

So now I'm wondering if he was correct about tadalafil not helping prevent/dissolve scar tissue, and whether only 2 daily does of pentoxifylline is enough, since I many guys here got prescribed 3x daily.  Seeing how dismissive he was of the tadalafil as helping prevent fibrotic tissue formation, maybe he's not caught up on best current practices, and should have prescribed me 3x daily? 

Should I try to contact him and push to be bumped up to 3 doses of the 400mg pentox daily?  I'm already annoyed that I had to go nearly 4 months without the pentoxifylline while waiting for the appointment, so now I don't want to waste more time on a daily dose that's too low to be the most helpful.