Peyronies Society Forums

Peyronies Disease TREATMENT Discussion Boards => Developmental Drugs & Treatments => Topic started by: Crooked_Stick on July 13, 2017, 01:44:15 PM

Title: Hydrogen-containing saline (HCS)
Post by: Crooked_Stick on July 13, 2017, 01:44:15 PM
For those who like to research medical stuff that may help Peyronies Disease:

https://www.spandidos-publications.com/10.3892/mmr.2017.6849/download

A solution of H2 saturated saline was injected into rats with pulmonary fibrosis. It appears the fibrosis was much improved.

"H2 abolishes the increase in TGF‑β1 and its downstream genes induced by pressure overload. TGF-β1 serves a key role in the
development of cardiac fibrosis."

If you remember back to the Xiaflex trials, there was a statistically significant improvement in the control group who were receiving saline injections. While not saturated with H2, the saline solution certainly contains some free H2. Could this have been the reason for the improvement? Maybe.
Title: Re: Hydrogen-containing saline (HCS)
Post by: james1947 on July 18, 2017, 07:26:22 AM
In my opinion, it is down to who is injecting, not what is injected.
But I am not an urologist, so is my private opinion.

James
Title: Re: Hydrogen-containing saline (HCS)
Post by: LWillisjr on July 22, 2017, 08:55:45 AM
I 100% agree with James.
Title: Re: Hydrogen-containing saline (HCS)
Post by: pey ron on February 18, 2018, 07:18:52 PM
Quote from: Crooked_Stick on July 13, 2017, 01:44:15 PMpressure overload

what does "pressure overload" exactly mean?