Peyronies Society Forums

I switched Viagra for Cialis a few days back. A concern was that I wasn't getting all that many nocturnal erections, and that Viagra is somewhat time limited too. The switch has been something of a mixed blessing. The nocturnal erections are now pretty frequent, which I'm happy about, and erections throughout the day are good too. The downside is that I appear to be one of the unfortunate minority to get pretty bad low back pain from Cialis. I will try reducing the dose to see if this helps, but it's a concern. Is there any chance that if I stick with it for a few weeks, the side effects will reduce somewhat?

Newguy,
Cialis is what I take. I don't know about the back pain. I haven't had any side effects. My insurace only covers 8 pills per week, so I cut my pills in half and take a "half pill" every other day. Seems to work fine for me.

Thanks for the reply. I think I'll try cutting the dose down, and seeing if that helps. When I took vaigra previously, the side effects (blocked up nose, slight headache) went away after a few days. I can usually tolerate drugs well. Heres hoping that it's the same with Cialis, a I believe it to be a preferable choice due to its long half-life.

I get occasional low back pain with Cialis. I am able to combat it with ibuprofen very well. I also cycle off for periods of time. I have not tried vardenafil which may be a good choice too.

Tim

Tim, I'm curious, why do you cycle off Cialis?  I have heard others say they believe the various PDE-5 inhibitors can build up a tolerance with consistent usage, but that cycling off for a while seems to result in restored efficacy.  Just wondering if that's what you're doing? ...

Nemo

I'm very happy to say that after the first few days, which were pretty rough, the back ache has now gone away totally. It appears that my body has adjusted to Cialis and all is well now.

I don't have a good single answer to why I cycle off medications or supplements. I get bored, discouraged and forgetful sometimes. At other times, I decide to take a break to see how I am doing without something. At other times I create scientific justifications like breaking down tolerances. But it's probably a bit of all of the above.

Tim

Cialis was a killer for me  in the back pain department.  I switched to Levitra

Quote from: Hawk on September 18, 2009, 10:00:13 PM
Cialis was a killer for me  in the back pain department.  I switched to Levitra

I was actually quite shocked at the level of discomfort I experienced. The pain was pretty bad, and even seemed to extend into my legs, though the back pain was the most intense. I'm surprised that it went away so fast really. Now I have no side effects from it at all. Whereas with viagra I occasionally used to get blocked sinuses. The good news I suppose is that, with three options the vast majority of people will find one option that works for them.

In young men with peyronie's disease, and I assume some with other conditions where ED is present, viagra can of course be very useful. It is probably the one drug though that I worry about taking for a prolonged period of time. It's not that I have any reason to as such (aside from the documented rare cases of hearing and sight loss) but I appear to have concerns anyway. Do you think that these concerns are warranted?  There are alternatives of course (l-arginine + pycnogenol and so on) so it's not as if they aren't other options, but they likely aren't as powerful. Are there any longer term studies of daily use phosphodiesterase type 5 inhibitors which highlight side effects / concerns?

Quote from: newguy on October 15, 2009, 09:53:34 PMAre there any longer term studies of daily use phosphodiesterase type 5 inhibitors which highlight side effects / concerns?

Depends on your definition of long term. Mine is 25+ years, but for some these 6-12 month studies will qualify.

http://www.empowereddoctor.com/daily-viagra-study

http://www.canada.com/health/Healthy+took+Viagra+Cialis+fine+Study/1492330/story.html

I can get erect without viagra right now, but it's not a good erection and  I read a few people here are taking viagra daily - and I sometimes see these commercials about "viagra for daily use" too.  How much viagra is in the PAV cocktail...and is it meant to be daily or every other day?  Are you supposed to have sex/masturbate right after that, or is the benefit just in taking the pill?

I can get an erection that is about 60-70% of what I had a year ago in terms of size and hardness.   If I am with someone I am really into, maybe it'll go up to 75-80% but it's still not the same.  Viagra makes it about 80% - but I only have taken it for certain occasions. ..not daily.

I am 30...so I would ideally somehow restore things to normal, rather than being on viagra forever...so I guess that's why I was wondering if my body can become dependent on it.  

Right now, I just started with all of this (it took some time to get diagnosed officially and to stop being in denial) so I have pentox, arganine, a VED device on its way in the mail, vit E, and Trazadone.  I had viagra prescribed before (before I knew i had Peyronies Disease officially...when things just "were small and not working right") and I have refills...but I never took it on a daily (or semi-daily) schedule.  

mikesmith1010,

You make a great point that I hope more here will try to understand. As I got older and my erection wasn't what it used to be, I was in denial about it. This was even before my Peyronies. What I was in denial about was that I was having mild ED and refused to admit it. As long as I was "hard enough" for entry/intercourse then I thought every thing was fine.

What I didn't realize is that in this "weakened" state, even though we could have intercourse, it was making me more vulnerable to trauma. This is definitely one of the conditions that causes Peyronies Disease and is what I believe caused mine. Any time your erection is less than 100% rigid, it is my opinion you are at risk of trauma or further injury. So don't fool yourself about being adequate or hard enough. If I were you I would use the viagra. You can either use it when you know you will need it, or take it in small doses to help blood flow and erection quality. I take Cialis but I still cut it in pieces and take it on a more regular basis. Mu insurance would not pay for the daily dosages.

I also have 100 mg Viagra and am able to cut it into 4 pieces (25 mg each). You can take this daily or every other day at your discretion.

Les

Can anyone tell me if there are generic brands of viagra, cialis and levitra online that are trustworthy? Thanks

Yes, there are trustworthy places online. I ve been buying Viagra, Celebrex and etc. For over a year and havent had any problems. If you would like to PM me I will give you the details.

Woodman

Hey Woodman - My name is Ken and I think you and I have the same Urologist, as I also live in the Houston area. Anyway Dr. Lipshultz put me on daily Viagra, its very expensive since my insurance doesn't pay for it. Can you provide a little more info on the online sites? I would greatly appreciate any data you could provide, Thanks.

Ken

Hello,

I have taken viagra from 25 - 50 mg and have had pretty good erections, but I have also had the bad side effects (headaches, flushing, congestion...had to take migraine med 1 time after viagra - pretty rough migraine). 

I took cialis at 20 mg for "36 hour use" and had zero side effects.  It lasted 36+ hours.  I thought I was 15 years old again based on how many erections I was having (from practically nothing). 

So, going forward, I have a few questions...

My urologist had a cupon for 30 2.5mg or 5mg "Cialis for daily use" tablets or 3 "10 or 20 36-hour cialis" tablets.  He wrote me an Rx for 3, 36 hr cialis (for free).  I didn't drop it off yet because I realized that the 30 tabs seems to make more sense for Peyronies Disease than the 3 long-acting tabs.  All these meds help oxygenate the penis and I've read posts where people say it can have benefits for Peyronies Disease especially with Pentox, Arg, Verapamil, and fast-size (I'm attacking from every front). 

So, should I go back and ask for daily-use cialis or can I split the 20 mg "36-hour" tabs up?  I can only really split them in half...so I'd only have 6 days worth.  I'm not sure if the tabs can be split but it doesn't say "do not crush or split this tablet" like some meds. 

Have any docs given people cialis for daily use instead of viagra?  It seems to be less intense of a drug & if it still benefits Peyronies Disease, then I'm onboard.  If only the 20 mg would have a benefit, then I'll just fill the Rx.   What have been your experiences? 

I've been splitting the 20 cialis in two. It's pretty much impossible to split it any more than that. If you get the 2.5's you can always double up (or triple,etc.)

I'd go back for the 30 day script mate. It is a pde5 inhibitor and works by the exact same mechanism as Viagra but with a much longer half life, it should be just as good for Peyronie's if not better than Viagra.

Far better to have it in your system for 30 days than just a few, and make sure you're having arginine for hte best result. I'll bet you see pretty much as good an erection with the 5mg once a day as you did with the full 20mg dose.

I have a question too. If there any evidence at all that people can build up a slight tolerance to these medications over time?

Quote from: newguy on May 14, 2010, 04:53:43 PM
I have a question too. If there any evidence at all that people can build up a slight tolerance to these medications over time?

There are a few reasonably long studies out there done on Viagra daily, and nothing was reported about building up a tolerance. Actually I remember the result of one was that a pretty good percentage of the participants regained the ability to have an erection without Viagra at the end of the study. That is from memory though, might be an idea to hunt them out and have a read.

The only place I have heard of people building up a tolerance is on forums, and in my experience anecdotal evidence is not something that should guide your actions.

Hi to everyone
I am just last week diagnosed and signed on as a member Tuesday. Have had lots of help from The Old Man and great correspondence with fubar.
For what it may be worth , my Urologist took one look at the photo I brought with me and said he would not even consider any kind of surgery for 1 year. Hopefully it will have cleared up by then. Let's hope!!
It first appeared about 5 weeks ago - just out of the blue.
He prescribed a daily 5 mg dose of Cialis. Plus use a vacuum for 5 - 10 minutes every night.
I am a heart patient so had to get clearance from my Cardiologist this week , because I carry Nitro but have never used it.
I can take the daily Cialis provided I don't use the Nitro if Angina strikes. He said get to a hospital and tell them no nitro.
He is one of the best P.D. Urologists here in Ontario and has over 20 years experience treating it. He has gone through several standard treatments and discarded most of , apparently ,them in favor of the above. But all I know is what he is doing with my case.
The Cialis has caused me to have multiple night time erections - curved of course. But I understand that is good so will stay with this treatment and hope it works for me.
Thanks for your time fellows.
Mike

I've read several posts in these forums about men taking viagra or similar drugs.  I'd like to understand more and see if it is appropriate for my man.

He is able to get and sustain an erection sufficient for (satisfying!) intercourse.  He's not as hard or big as before but that's okay (with me at least, not him necessarily).  Therefore I thought Viagra was not appropriate, because it was for treating ED.  

However am I reading correctly that there are therapeutic benefits to the drug?  His doctor did not mention this, but we can push for a prescription if it is valuable.  

So my questions are:
- should he take it?
- should he take it daily or just before sex?  (which for us would mean once or twice a week)
- if daily, how much?  I assume a much smaller dose than the 50-100 mg one would use for ED
- My pharmacy charges $20 per 100 mg pill!!!!  (Yes, I know this because I take Viagra.  If you are curious about that, send me a private message.  I don't have Peyronies! : :) )  They say there's no generic version available.  However the internet insists there ARE generics for sildenafil for $1-2 a pill.  Are these legit?  Are there trustworthy online pharmacies?
- Are there any studies (ideally double-blind placebo, but even open label or case studies would be helpful) showing therapeutic benefit to viagra to help convince the doc to prescribe?
- Has anyone had any luck getting their insurance to cover viagra, especially if a daily dose is required to treat a diagnosed non-ED condition?

(I have a ZILLION more questions so maybe everyone will get sick of me asking but I hope you will be patient.  I do try to read forum highlights but often they don't cover my specific questions.  Thanks!)

(Oh, edited to add, he's currently taking Colchicine and Pentoxifylline)

As far as therapeutic benefits, Pentoxifylline is similar to Viagra in that it increase blood flow to the penis. However.... you stated something in your post that caught my attention. You stated his erection is "hard enough" but not as hard as it used to be. I can tell you for me, that this is what I feel caused my Peyronies. I refused to admit I might have slight ED, and my erections were also "firm enough". But what I didn't realize is that my erection was more vulnerable to trauma/bending in this state. And some slight trauma can trigger Peyronies Disease. So my advice would be to use either Viagra/Cialis/Levitra and advise him to keep his erection as hard as possible. My preference is toward Cialis in that is lasts much longer than the Viagra does.

Personal experience here - your mileage may vary...

I like Cialis over Viagra for several reasons.

The biologic effect is the same - the Nitric Oxide effect on erection is also thought to positively affect wound healing. I do note, though, that some docs I consider more current and "state of the art" no longer are using it. For instance Tom Lue in SF did his first case report on Pentox for a guy who was also given Viagra. I think he no longer adds that in as it does not seem to add to the benefits from pentox.

It is important to remember that Pentox and Viagra do different things to the body, and "improving oxygenation" or "vasodilators" or "blood thinners" is not either what they primarily do, or what their putative mechanism for helping Peyonrie's disease is.

Secondly, the dosing can be spaced way out. It is my experience that the benefit to erection quality grows over time with Cialis. NOw after taking it for about two years, I note that I dose it only every 5 days or so, and the benefits (in terms of hardness and "quality" no longer washes out within 36 hours like it used to. There are now published reports that long term use of this class of drug can lead to improvement in baseline function in men with ED.

Third, I can save money by using Cialis as I can space it out more (if I buy a 20 mg tablet and break it into fourths and take 1/4 every three days, it can work quite well. I sought out and found a good source of cheaper Cialis over the internet and saved more that way as well.

Finally, the side effects with Viagra are worse for ME (headache and flushing) so that affected my choice as well.

Tim

I'm with Tim on this one. I found that I experienced more side effects on Viagra than Cialis - headaches, clogged sinuses etc. I did initially have problems with Cialis in that for a few days it gave me bad pain in my lower back. After that however it was plain sailing. I like that Cialis has a very long half life, and figure that the longer something is in my system the more opportunity it has to do good. I also agree with Tim on the point that, after taking it for many months, now if I miss a dose for a few days, my erections still seem to be much stronger than they were pre-cialis. There are indeed studies to back up the claim that after a long time on these medications, erection quality is greater even after you stop taking them. Whether this is physical or psychological (or both) I do not know, but that is less important to me that the occurence of the erections.

Hi,

I was wondering if you would be so kind as to give me a pointer to these "trusted places" where you can buy medications.
I have been a lurker on these forums until recently but I really cannot afford $18/pill anymore :(

Thanks!

ps: Woodman, your pm box is full.

Quote from: ccc on October 10, 2010, 04:31:27 PM
Hi,

I was wondering if you would be so kind as to give me a pointer to these "trusted places" where you can buy medications.
I have been a lurker on these forums until recently but I really cannot afford $18/pill anymore :(

Thanks!

ps: Woodman, your pm box is full.

At least viagra is one drug where it's possible to know whether it works or not. Of course though, there is always risk, there are no certainties. I have personally bought Cialis from riverpharmacy.com . I know a few people here use bmpharmacy.com too. Both seem to be reliable. As luck would have it the quality of my erections appears to have improved somewhat over recent months. It isn't a wholly anticipated development but it's welcome nonetheless. Therefore, I plan to reduce my useage of certain drugs over the months.

FCC

Riverpharmacy worked for me 3.00 $ something rather than 24.00 a pill here in the US.woke up today with annoying bent erection!

Fubar

Quote from: fubar on October 15, 2010, 09:31:51 AM
FCC

Riverpharmacy worked for me 3.00 $ something rather than 24.00 a pill here in the US.woke up today with annoying bent erection!

Fubar

I'm glad others have positive experiences with them too! Yes, there's certainly a potential saving there for men who have been paying more previously, for one reason or another.

I'm new here and would like to keep my wife happy.  Noticed nodules/beginning of bending/indentiation about a year after surgery for rectal cancer.  I have no problem getting and keeping an erection, but since surgery I have trouble fully emptying my bladder without straining, and I no longer get spontaneous, overnight, erections.

My urologist has me on Vitamin E, daily cialis and l-arginine, which he says have off label anti-oxidant effects.  After 30 days he'd like to introduce another drug (trentinol??).

I have it in more than one place.  Have heard about the surgery connection.

Any thoughts?  I keep seeing stuff about pentox and ubiquinol.

If momma ain't happy, nobody is happy.  LOL

Trental is a brand name for pentoxifylline, aka pentox, and is considered to be a first line medicine.  400 mg tablet, 3 times per day, with food, is common.  Generic is cheap.  Vitamin E is considered to be a waste of time.  The L-Arginine and cialis are to encourage night time erections, which increase blood flow and full vascular filling.

Quote from: gm on November 23, 2010, 06:33:50 PM
I'm new here and would like to keep my wife happy.  Noticed nodules/beginning of bending/indentiation about a year after surgery for rectal cancer.  I have no problem getting and keeping an erection, but since surgery I have trouble fully emptying my bladder without straining, and I no longer get spontaneous, overnight, erections.

My urologist has me on Vitamin E, daily cialis and l-arginine, which he says have off label anti-oxidant effects.  After 30 days he'd like to introduce another drug (trentinol??).

I have it in more than one place.  Have heard about the surgery connection.

Any thoughts?  I keep seeing stuff about pentox and ubiquinol.

I'm beginning to see a correlation between my use of Cialis and painfull inflammatory flare ups of my Peyronies.  I use the Cialis only occasionally to induce nocturnal erections.  After Cialis I am extra sore for 2 or 3 days.  Perhaps the erections with Cialis are too strong and strain the already compromised tunica.  It's not a popular opinion on this board but I suspect the use of all these ED drugs has caused a hugh surge in Peyronies occurrences.

you may have a point.  I think that's one reason a lot of doctors are hesitant to prescribe them, especially if you have no physiological ED.  I don't have any problems getting an erection unless its psychological from the anxiety of having Peyronies Disease.  I notice that when i take something as mild as L-arginine to help with this, i sometimes get pain.

It does help with prevent scarring in animal models, so in situations where it appears to bring on more pain, I guess it comes down to the individuals decision. It's sometimes hard to know what to do. In those new to peyronie's without ED, there might even be an argument for cialis there, due to its anti fibrotic effect (granted some/all of that might be due the erections but who knows). If I had recently developed peyronie's, I think I'd throw everything but the kitchen sink at it (in terms of things that we know might help).

I agree Newguy, I think anything that helps induce erection will have an anti fibrotic effect on peyronies, since the increased blood flow is getting into more tissue to carry nutrients to it, and the erection itself will keep the scar tissue stretched.  However I have a fear about taking these drugs(cialis,viagra,levitra) for Peyronies Disease sufferers with no ED.  One of the risks of taking these is priapism, which men that have no ED are much more prone to, since there is nothing wrong with our erectile quality in the first place.  My concern would be nocturnal erections that are priapistic in nature, and since you're sleeping, you may not even notice it.  This would seem to me to worsen or aggravate the disease greatly

Quote from: chefcasey26 on December 03, 2010, 06:04:42 PM
I agree Newguy, I think anything that helps induce erection will have an anti fibrotic effect on peyronies, since the increased blood flow is getting into more tissue to carry nutrients to it, and the erection itself will keep the scar tissue stretched.  However I have a fear about taking these drugs(cialis,viagra,levitra) for Peyronies Disease sufferers with no ED.  One of the risks of taking these is priapism, which men that have no ED are much more prone to, since there is nothing wrong with our erectile quality in the first place.  My concern would be nocturnal erections that are priapistic in nature, and since you're sleeping, you may not even notice it.  This would seem to me to worsen or aggravate the disease greatly

Chef - Some very good points. I feel that people should certainly listen to their body when making choices. If a man taking ED medications finds that his erections are lasting loing than he'd like them too, then it may be risky - in terms of priapism. I think many men with peyronie;s have varying degrees of ED so I haven't heard of cases of priapism here, but it's certainly something a persons hould consider when starting on a treatment. It's a very valid point that its hard to know how many erections you have to night and how long they last for. The only obvious measure would be more often an individual wakes up during the night, or in the mornings with an erection, but that's not a perfect representation of what happens during the night. If erections lasted for ages though I'd expect that the man would wake up with penis pain.

Priapism is something that is very painful when  having erections for an over extended time. Usually over three hours. I did experience ed for a time ,now I do not.I still use cialis every now and then to keep a good erection to promote healing. The drug is different than viagra no instint hard on.

I feel  being a heart patient that it is very safe. You should always consult a doctors advice though before taking matters in your own hand.

Fubar

I have been on a short course of low-dose Cialis for 4 weeks now as part of my post-surgery treatment. I had tried full-strength Levitra when I wasn't having any erections after the surgery - and the stuff made me too sick. The low-dose Cialis, which is taken every day, had a couple of nasty side effects the first week and a half, and then settled down. What it has revealed is that there is nothing wrong with my libido, and I expect I will have very little trouble with ED after the 6 weeks are over. I didn't really care for the side effects much - initially I had stomach upset and crashing headaches, but the only one I am left with is a tendency to have a hot, dry face. For 6 weeks, I can live with that. And my doctor was a brick - the Cialis low-dose samples come in 2-week packages, so I do not have to pay for a prescription unless I want to continue beyond the initial therapy period.

I have not had any evidence of priapism with this approach - but then, I was never much prone to nocturnal erections or emissions.

I initially had bad side effects too. Pretty nasty indigestion and bad lower back pain. Luckily this settled down after a couple of weeks and neither has been an issue since.

My case of peyronies is due to multiple fractures, I guess you could say, that took place when I was very young - I'd guess 14-16 years old. I'm 26 years old now.

My penis has had a very slight bend for many years since the trauma. It doesnt seem to have gotten much worse over time. However, in the last 3.5 years I've experienced ED. 3.5 years ago I could have sex without drugs. Now, however, I cannot - I need pde5 inhibitors just to get an erection adequate for penetration. In fact, I even struggle to masterbate successfully without them! Never imagined I'd be in that position!
It's taking a severe mental toll on me. I assume these problems are due to the plaque caused by peyronies. There is some noticable harder areas where the bend and the trauma occured.

I have seen contradictory information on peyronies and pde5 inhibitors. Some say they are bad or make it worse. Others say they are good because they stimulate blood flow.

Anyone have any ideas, advice, or experiences?

IMHO anything you can do to stimulate blood flow to your penis is good for you.

The pills and shots id not work for me. I used a VED for years before having my implant. Dr. Milam said to keep up the daily VED exercise until the day before surgery. I firmly believe that helped my outcome.

Jackp

The oral treatments that actually "work" for Peyronie's are Pentoxifylline and Ubiquinol/Ubiquinone, and Acetyl L Carnitine and Potaba.  They are the ONLY treatments that actually have research study support showing significant benefit for Peyronie's.  With the exception of Pentoxifylline, they do not improve blood flow.  They are rather powerful anti-oxidant/anti-inflammatories.  Pentoxifylline improves blood flow and blocks the immune system reducing inflammation as well.  The first two are undoubtedly the best choices.  PDE5 inhibitors work for ED, there is no question about that.  Lots of research data behind that.  AND, if your Peyronie's is accompanied by ED, fixing the ED with PDE5 inhibitors will be helpful for the Peyronie's, but it will not benefit Peyronie's problems directly.  So don't try to substitute Peyronie's treatments with PDE5 inhibitors.  If you need both, use both.  But attack Peyronie's directly if you want the best outcome.  - George

Quote from: George999 on January 08, 2011, 10:39:22 AM
The oral treatments that actually "work" for Peyronie's are Pentoxifylline and Ubiquinol/Ubiquinone, and Acetyl L Carnitine and Potaba.  They are the ONLY treatments that actually have research study support showing significant benefit for Peyronie's.  With the exception of Pentoxifylline, they do not improve blood flow.  They are rather powerful anti-oxidant/anti-inflammatories.  Pentoxifylline improves blood flow and blocks the immune system reducing inflammation as well.  The first two are undoubtedly the best choices.  PDE5 inhibitors work for ED, there is no question about that.  Lots of research data behind that.  AND, if your Peyronie's is accompanied by ED, fixing the ED with PDE5 inhibitors will be helpful for the Peyronie's, but it will not benefit Peyronie's problems directly.  So don't try to substitute Peyronie's treatments with PDE5 inhibitors.  If you need both, use both.  But attack Peyronie's directly if you want the best outcome.  - George

Are there serious side effects to pentox and ubiquitol? I have heard that many doctors are hesitant to prescribe them.

Quote from: jackp on January 08, 2011, 08:32:50 AM
IMHO anything you can do to stimulate blood flow to your penis is good for you.

The pills and shots id not work for me. I used a VED for years before having my implant. Dr. Milam said to keep up the daily VED exercise until the day before surgery. I firmly believe that helped my outcome.

Jackp

It seems like you are satisfied with the implant. If that's the case, I'm happy for you. Anyone who gets through these problems and ends up with a satisfactory outcome is a ray of hope.

Quote from: ShadesOfBlue on January 08, 2011, 01:15:28 PM

Are there serious side effects to pentox and ubiquitol? I have heard that many doctors are hesitant to prescribe them.

Ubiquinol is over the counter...i dont think there are major side effects.

Pentox can cause insomnia, sleep disturbances, anxiety, and stomach upset in susceptible individuals.  Generally, people don't experience any problems.  When I took it, it messed up my sleep somewhat & I woke up a lot during the night.  Some others on here have reported this as well - and so it's best not to take it close to bed time... which makes it hard to take 3 divided doses.  The best solution for people w/ problems on pentox is probably to just take 2 pills a day instead of 3 (all at 400 mg, which is the only dose it comes in i think) w/ breakfast and maybe then no later than 6 pm or so - depending on when you go to bed.  The pill is naturally "time release" from what i heard anyway, and your body maintains a certain level of the drug in your blood for a while - so even timing your doses may not help if you are very sensitive to it. 

I take Pentox three times a day.  I NEVER take it after 6:00PM and usually my last dose is around 5:00PM.  I take it breakfast, lunch and dinner and have never had any problem with sleep disturbances probably because by the time I go to bed it is pretty much out of my system.  - George

I have a prescription for Cialis (20mg) which I've used (5mg dose) when I know I am going to have intercourse to gain a firmer erection (and hopefully prevent again further injury). I have not been using it on a daily basis or every other day basis for two reasons. First, cost. Second, I am a little concerned about the long-term impact of taking this daily.

That being said, I've seen the evidence for the PAV cocktail and am thinking about moving my intake to a daily basis. To save costs I'm wondering about splitting the pills six ways (~3mg/dose) and only taking once every 48 hours? Cialis seems to run about $1/mg so this would bring my daily cost to about $1.50 which is much more manageable than the $5/day I'd be spending taking a 5mg pill daily.

Any thoughts on this strategy?

@dannyocean - I bought generic cialis - Tadalafil - and split the tablets.  Am taking 3mg - 4mg daily.  Works great from an erection perspective, also can tell while flaccid that the bloodflow is much increased.  You can get generic cialis for about $2.00 a tablet....

Apologize, can't seem to find the post I read recently that had a link to results of a Cialis study for Peyronies.  Can someone post again please?  Can't seem to find it on Google search either.

Thanks

Here you go:  http://www.ncbi.nlm.nih.gov/pubmed/21324095

Quote from: blackseal on March 04, 2011, 03:47:45 PM
@dannyocean - I bought generic cialis - Tadalafil - and split the tablets.  Am taking 3mg - 4mg daily.  Works great from an erection perspective, also can tell while flaccid that the bloodflow is much increased.  You can get generic cialis for about $2.00 a tablet....

Where did you get it? The stuff i got from alldaychem was not very effective.

I think this is exciting.  I've sent a letter to my Dr asking if he would prescribe me Cialis as another part of my treatment regimen (currently Pentox, ALC, L-Arginine, Ubiquinol).  Only thing that concerns me in this study, was that the scar tissues were not palpable among these men, but only seen with ultrasound.  And the Cialis group included young men, (although the average age between the two groups were about the same).  But, still the findings represent good news I think for us.

I agree.  This IS pretty cool and an aspect of Cialis that none of us really understood before.  My assumption was that it was improved erection quality provided by Cialis that caused improvement.  But this research seems to be indicating a direct benefit from Cialis itself.  That is indeed cool stuff.  - George

Blackseal

Thanks for leaving that link i needed the boost.Another reason to stay with cialis! I was told that it can help scar tissue bit to read about has a better impact.

Fubar

I would like to try this but I doubt the NHS will pay!  The NHS seems good for so many things but not peyronies!  I wish i had private healthcare.

Worried Guy

Try telling them you need it for erectile dysfunction. ED is more recognized as a problem anyway.

Fubar

Hi Skunkworks.  I got mine here:  tabsmarket.com/cialis.html

Works very well for me. 

Good luck!

Trazodone is really cheap and can be taken on a daily basis. I notice my nighttime erections are amazing and regular sex drive and erection strength during arousal is much better aswell.

I take 25mg, 1 hour before bed with food. I swear it has helped the healing and a nice flacid hang during the day.

I think the wildcard here for Peyronie's is that there is now a new study out claiming/showing that Cialis can actually heal Peyronie's scar tissue.  That is pretty impressive.  Your not only looking at improved erections, but also ACTUALLY HEALING OF DAMAGED TISSUES.  I don't *need* a PDE5 drug for ED, but for sure at this point, I am going to talk to my uro about cialis for Peyronie's.  - George

It looks like a decent study, even though the sample size isn't nearly as large as the pentox or coq10 studies, and they were much more extensive in terms of Peyronies Disease specifically.  I'm just a little skeptical.  There are so many guys on this forum taking cialis, yet I haven't heard of anybody who said it's helped their Peyronies Disease, only ED. Then again, The same guys are usually on a combination of drugs so it's tough to isolate variables.  I'd try it if a uro would prescribe a low dose, although with pentox and L-arginine, my erectile quality is already through the roof(which is nothing to complain about  :D), I'd be scared of any possible priapism though with everything else.

You might have a better shot if you say the Cialis is for fertility.

I guess at the very least it's another tick in the box, confirming that current treatment strategies are pretty much on target. Those men coming here, newly diagnosed, and being pushed in the direction of the PAV cocktail type treatments, or maybe more updated regimens which include CoQ10 and a 24hour+ PDE5 inhibitor (cialis) instead of a partial day one, are on the right track in my view.

One reason I switched from Viagra to Cialis is that I considered that its positive effects might extend beyond that of simply gaining a stronger erection. As such, it would make such to have it in your system 24/7. Of course it may well be the case that the stronger erections are what causes these improvements, the jury is out on that one I guess. As the study didn't even relate to deformity, maybe it's of limited use to us. Still, if the core finding relating to scarring is true, then it's definitely good to know.

Men in the study presented at an average of 22 months, and yet according to the study results this wasn't an excessive time period. With the previous pentox study, the time period was a year +. There seems to be this overriding idea among urologists that a point is reached quite early on, where oral reatments become useless. I think over time, that stance is looking to be on shaky ground. I would agree that 'logically' scar tissue is scar tissue, and as such you should not expect it is change much over time. However, in so many ways peyronie's scarring doesn't always appear to behave like scarring as you would typically recognise it. Well, maybe that's an overstatement, sometimes it does, but maybe in some cases, the tissue seems to be more 'in limbo', and can maybe be nudged in one direction causing improvements years after onset, if the right treatment approach is taken.

I think the good news here IS that these men had no real deformity.  This would mean that there was no serious amount of stretching going on.  And if Cialis wasn't causing additional stretching, there has to be some other mode of operation whereby it was bringing about the healing of the scar tissue.  And that is not only good news.  It is very good news because it shows that Cialis is therapeutic aside from its erection producing capabilities.

I think perhaps the percieved failure of the Viagra component of the PAV cocktail was due to Viagra being aimed more toward erection strength (ie ED issues) than toward pure non-erection related Peyronie's issues like resolving scar tissue.  And that was directly related to practitioners simply being unaware that PDE5 inhibitors are more than just a one trick pony.

The whole idea that after a certain amount of time everything is hopeless when it comes to Peyronie's is simply infuriating to me.   When you go to the doc with Peyronie's, what does he usually tell you?  Of course, just calm down and wait and see what happens because this thing usually just clears up on its own.  And he sends you home with instructions to relax and take some vitamin E.  Then you come back after a bit and it hasn't cleared up and then what does he tell you?  Well then he tells you its now too late to do anything about it and he offers to refer you to a good surgeon.  Whats wrong with this picture?  Is this good medicine or what?   I would assert that from the beginning to the end these doctors don't understand Peyronie's and quite frankly don't know what they are talking about and they are dooming their patients to wrong choices and protracted psychological and physical pain.  And that is why I for one am absolutely rabid about encouraging Peyronie's patients to go to a Peyronie's specialist IMMEDIATELY and not fool around with these ignorant small time docs who may be outstanding doctors when it comes to treating everyday health issues, but when it comes to arcane things like Peyronie's, they are more lost than the patient.

Cialis is so freaking expensive though. To run that 6 month treatment would cost quite a bit with the namebrand stuff, and I'd have to find a liquid that cialis is soluble in to cut the dose to 2.5mg as apparently it is insoluble in water...

My gf is a doctor though so getting it prescribed is no difficulty.

Can someone explain the healing part though? I am not 100% sure what "resolution of septal scar" means.

my interpretation of the study is this - the scar was not palpable and did not cause deformity as it was "septal" so less on the surface and more deep in the area seperating the chambers of the corpora. Therefore ED symptoms but no typical Peyronies symptoms of curvature. Still a scar is a scar, so this interesting.

Perhaps, if the study is correct, it's easier for Cialis to eliminate or reduce scarring in some areas of the penis compared to others. I think if Cialis alone was capable of causing very dramatic differences in actual deformity, we'd have heard about it. Of course though, there are disease stage related issues,  and issues relating to degrees of improvement and time taking the treatment etc. I think there is possibly a bigger window in the early days for really hitting this disease from all angles (pentox, l-arginine, pycnogenol, cialis, coq10, ALC, mechanical treatments etc). And of course as stated earlier in this thread there it might be a mistake for those with long term peyronie's to simply assume that there is no spoke for improvement with these treatments too. If more men stick with potentially effective treatments for a decent span of time (1 year+), I think they'll often time themselves in a better place.

We've spoken before about how in some ways, we don't view anything other than a total resolution of pyronie's disease as an improvement. Any reduction in worsening or curvature is a good thing though, and puts you in a better position even if you do eventually go on to more invasive treatmnents like xiaflex or surgery. There's also a preventative aspect to a good treatment plan. I'm of the believe that if further injury or inflammation occurs, these might well often be nipped in the bud if you're already on an effective treatment regimen.

Quote from: newguy on March 13, 2011, 01:56:33 PM
Perhaps, if the study is correct, it's easier for Cialis to eliminate or reduce scarring in some areas of the penis compared to others. I think if Cialis alone was capable of causing very dramatic differences in actual deformity, we'd have heard about it.

Not many would take a daily dose of cialis for 6 months. Though its use is widespread, chronic use is not.

Yea...This study wasn't particular to Peyronies Disease.  "Isolated septal scarring" is much less serious, such as a one time  injury to the septum, rather than a continuous inflammatory process such as Peyronies Disease.  Septal scarring and tunical scarring should be the same thing, the only difference is the septum is the part of the tunica that wraps the chambers in between rather than around, but the same tissue none the less.  So if it was successfull in resolution of those scars, I see no reason why  it wouldn't resolve in the tunica.  

Why did they choose isolated septal scars instead of or not in addition to isolated tunical scars?  Who knows.  I do know that septal scars are much more painful than tunica scars(probably because it's a tighter space, more nerves, etc.), as I have both of them confirmed by ultrasound.  It's impossible to see any deformity from septal scars because they are in the middle of the two erectile bodies.  So maybe this was a study based purely on men having pain from septal scars.  

Anyways it's still interesting, so I will ask Dr. Levine about it as well as a lot of other questions on my mind when I see him in 3 weeks.

Quote from: skunkworks on March 13, 2011, 04:52:40 PM

Not many would take a daily dose of cialis for 6 months. Though its use is widespread, chronic use is not.

Fair point, but I don't think it's entirely unheard of. It might be that those on such treatment have had improvements that they didn't put down to this. Unless something has a very dramatic effect, it's often difficult to know what to put the improvement down to. At least now that we're aware of this study, we can better keep track of what improvements people have, and plot them against the treatments they're on.

Quote from: chefcasey on March 13, 2011, 05:22:17 PM
Yea...This study wasn't particular to Peyronies Disease.  "Isolated septal scarring" is much less serious, such as a one time  injury to the septum, rather than a continuous inflammatory process such as Peyronies Disease. 

Yes, maybe that is a factor here. Still, if it can help a one time injury, it may be contribute to helping or dampening  down peyronie's processes. At least with it working 24/7, it may add to the effectiveness of other treatments to make a more potent approach to peyronie's disease treatment.

If i take cialis, I have really intense nighttime erections - and i wake up with them too... I am getting worried that i might actually be erect all night ... is that even possible?  I don't want to make things worse & priaprism leads to MORE scarring so that's the last thing I need.

Nothing hurts though... and it basically goes away right after I go to the bathroom (but not when I just  stand up and get out of bed which I think is what normally happens?  It's been 5-6 years since I had natural morning erections i can't remember).   I never have nighttime erections like i do when i take cialis  (and cialis as needed is allowed on the xiaflex trial btw)...and it's a really long acting drug.

On the flip side, maybe there is benefit to having nighttime erections again (assuming they come and go and it's not erect the whole night) in that it allows in oxygen, etc... again.    

I would think that's it's possible. I can see why you'd be concerned, if you're waking up with strong erections. Waking erections are of course perfectly normal though. I personally don't think that there's reason to believe that you have personally experienced it. If pain was present I'd be much more concerned.

Just added a new post to the Cialis discussion page on Wikipedia.  Hopefully more doctors will read this and be open to prescribing it as another weapon in our arsenal of treatments.

Anyone know what cialis is soluble in? Not water.

Yay!  My doctor prescribed me the low dose daily Cialis.  I like that he is open to trying many options.  His reasoning is it certainly can't hurt to try.  The first urologist I went to hadn't even heard of using pentox, Ubiquinol, ALC, or other oral treatments.  And he graduated from the Mayo Clinic!  Why arent urologists staying abreast of these newer treatments that do have objective evidence from studies that they help? 

Quote from: restore on March 22, 2011, 11:35:35 PM
Yay!  My doctor prescribed me the low dose daily Cialis.  I like that he is open to trying many options.  His reasoning is it certainly can't hurt to try.  The first urologist I went to hadn't even heard of using pentox, Ubiquinol, ALC, or other oral treatments.  And he graduated from the Mayo Clinic!  Why arent urologists staying abreast of these newer treatments that do have objective evidence from studies that they help? 

Because they want to keep us sicker and make more money off us. You don't make any money if you just cure the person. I'm totally just joking, lol.

How many mg is a low dose of Cialis? How much are you paying for it?

It's 2.5 mg, and 30 tablets.  Picked it up yesterday at my local CVS pharmacy, cost was $136.00.  
That's my portion after my Blue Cross pays whatever it pays.
I asked, and pharmacist said there is no generic version.

Restore

I have blue cross also and they don't pay much. I believe my first purchase of 10 pills at 2o mg cost me 197.00 .There is no generic in the states this is why I by mine from rivrfarmacy generic yes differences in how they work none. I would much rather pay 3 dollars on a pill than 24.00.

Fubar

I'm thinking about taking low-dose Cialis for it's healing properties. I don't have a problem with ED so that's why I will be taking the low-dose form. But I'm wondering what a low-dose Cialis is?

Does Cialis up ones labido? Has anyone notice if the drug wore off after awhile? Because I was taking Trazodone (25mg) before for nighttime erections and I noticed the drug wore off after awhile, usually in about a month time.

I'm going to see the doctor tomorrow about Cialis. I'm going to lie and say I have ED problems because I'm afraid if I tell him the truth that he won't prescribe it to me. I don't think he will prescribe me low-dose Cialis because it has anti-fibrotic healing properties.

What dose should I ask him for? I don't want to high of a dose because of priapism risks.

Thanks

Crashbandit, this may work for you too, I printed out the summary of the Cialis study results and showed it to my uro, and he agreed to prescribe it for me.  Its the same low dose in the study, 2.5 mg daily.  My uro feels it's worth trying especially given the recent research that supports it.  He felt there is no harm done to try, maybe yours will feel same way.  Think it's good to stay honest with the doc you're working with in fighting this condition.  If he says no, you may want to work with someone else.

Thanks restore, I''l ask him for that dosage then, 2.5 mg. And I'll take it just before bedtime every night. I hope the Cialis gives a nice healthy hang during the day, and avoid the hard, shrunken flaccid state that I've had recently.

How has your experience with Cialis been so far restore?

I've just started it, but have noticed a weightier longer flaccid state during the day, feels good.  And it gets hard quickly when thinking of sex or when my wife and I start to engage in foreplay.  The study was 6 months long, so I'm really curious if I'll get some scar reduction in the longterm.

Hmm just wondering..
All studies I have seen speak of 5mg doses..
I wonder if 2.5mg have the same effect.. Actually low dose cialis can be bought in what they call "monthly supply" that is 30 doses at 5mg

It would be interesting to see a comparative study (probably does not exist) for 2.5 vs 5 mg daily.

what about dependance???? is there any risk of not being able to establish a firm erection without the aid of cialis after prolonged low dosage use???

Cialis helps to inhibits an enzyme in your body that would otherwise cause blood to leave the erection - like viagra and the other PDE5 inhibitors, because it is simply blocking the action of a chemical produced by your body and it is not introducing or increasing the levels of a particular chemical into your body, user's are not at risk of becoming physically dependant on it.

Psychologically people may come to rely on it but personally I have found the drug to be very helpful - it's not as intense as viagra, doesn't have the same side effects and it has a much longer half life (i.e. it takes longer for the body to break it down) hence the fact that it is the only ED drug that is approved for daily use as it builds up in your system as you take it day by day.

Do any of you have a link to the Cialis study you're referring to?  It sounds like an interesting read.  Thanks.

Humorous

http://www.ncbi.nlm.nih.gov/pubmed/21324095

One thing to keep in mind about this study, none of these men had palpable scar tissue.  But the improvements they achieved in erection quality is encouraging.

You have to wonder about some of these studies.  69% showed improvement?  I seriously doubt it.  Just reading this board tells you that very few see improvement of any kind no matter what the treatment.  Sorry for the negativity.  That's just how I see it.

Hornman

Hornman

Whether or not cialis will straighten a Peyronie's penis is yet to be seen by any of us .Cialis does do what it is made to do though and does help keep your unit healthy.By getting the blood down there and helping those who are not having night time erections.

Cialis and pentox have helped my flaccid state greatly.Adding ubiquinol has made a tremendous difference. My flaccid state elasticity has improved alot no more tight non moving weeny.

I would not worry about seeming negative as we all have those feelings about this condition.I know I have them often and often express them through pm's and the forum.That is what its for to share knowledge and vent.

Fubar

I thought being on 7.5 mgs of coumadin every day for my heart would "thin" the blood enough so that there would be plenty of blood going down to the penis....but I was mistaken.  Having read many posts about Cialis in the forum, I asked  my internist about Cialis.  He  told me that Cialis acts differently with the blood as far as "thinning the blood goes".  Since he prescribed Viagra before, he advised me not to mix them.

The Cialis was more than I needed everyday, since I had many early morning erections, I didn't know what to do with.  My wife told me I could poke her anytime in the morning but then she didn't like it at 4 am.  The erections kept me up most of the morning.

Finally, I decided to take them every other day, and now I take them about twice a week.  There is no problem with getting erections, and I believe that viagra would induce a harder more firmer erection than the cialis.

The only thing that really hang are my balls.  I got a set back since I stopped using the VED for awhile.....

The 2.5 is good therapy and you have to find out for yourself what works best for you.

ym

I don't have ED but am using Cialis for the healing properties. I popped my first 2.5mg today and like it so far. My flaccid penis is already a nicer hang and the blood flow is great. My question is whether I should take 2.5 mg daily or maybe every second day?

Would 2.5mg daily be too much for a non ED person? I guess I could always test out the 2.5 mg daily and see if I like it.

For all you americans, you can get a free trial period for cialis. go to the cialis home website, http://voucher.cialis.com/index.cfm. Just print off the voucher and take it with your prescription to the pharmacist.

I hope to see reduction of pain with Cialis soon.

Most studies say, that cialis for therapeuthic usage in Peyronies Disease, is dosed at 5mg/day
(for ED or for sexual enhancement cialis comes in 20mg doses that last for like 36 hours)

Anybody notice Cialis lose it's potency after awhile? I've noticed this in the past with Trazodone. Trazodone would give great nightly erections but after a months time, these effects would wear off. Any long term cialis users notice this at all?

Quote from: Brightdog on December 13, 2010, 10:09:47 AM
I have been on a short course of low-dose Cialis for 4 weeks now as part of my post-surgery treatment. I had tried full-strength Levitra when I wasn't having any erections after the surgery - and the stuff made me too sick. The low-dose Cialis, which is taken every day, had a couple of nasty side effects the first week and a half, and then settled down. What it has revealed is that there is nothing wrong with my libido, and I expect I will have very little trouble with ED after the 6 weeks are over. I didn't really care for the side effects much - initially I had stomach upset and crashing headaches, but the only one I am left with is a tendency to have a hot, dry face. For 6 weeks, I can live with that. And my doctor was a brick - the Cialis low-dose samples come in 2-week packages, so I do not have to pay for a prescription unless I want to continue beyond the initial therapy period.

I have not had any evidence of priapism with this approach - but then, I was never much prone to nocturnal erections or emissions.

Ditto on the crashing headaches and lower back pains. I havn't been feeling to well overall since starting Cialis. I hope they stop after a couple weeks like you guys.

I found a website online that is a much better deal for Cialis then at my pharmacist. It is:

https://ph-u.com/buy-cialis-usa.html (https://ph-u.com/buy-cialis-usa.html)

Anyone use these guys? I ask where the Cialis is made and they said India. I asked them if the factories are under the same regulations as they are in the States and they said yes. I pay $2.50 for a 2.5mg dose from my pharmacist, which translates to $70 a month. Through that website, I could pay 20mg pills x 60 for $155 (plus $10 shipping), which translates into 480 days of 2.5mg doses. Obviously the india supply is much cheaper.

Is the Tadalafil from India good? I don't think it would be any less effective or different then the USA stuff. Maybe there is another website that is alittle more expensive but the Cialis is made in the USA?

Crash

Yes,cialis from India works! Good stuff can not tell the difference from the USA.?

Fubar

Thanks Fubar, I'm gonna do it. I have an awesome drug plan that covers everything, but still they don't cover ED treatments for some reason. Do any drug plans cover ED drugs?

Crash

No, They know men will pay to have a quality erection.I. have great insurance I paid 185.00$ for heart surgery and a three day stay in a hospital.10 pill of cialis 240. 00$ I would have to pay 197.00$.Go figure guess its their way of keeping the population down and not passing on defect genetics.Cost me more for ten erections than to employ a heart surgeon and all the other stuff that goes along with having a failing heart?

Fubar

Mike

From what I have heard priapism is extreamly painful.As long as you are not taking viagra you will be fine.That is the beauty of cialis and why it is costly.Erections when you need one.Not like viagra instant erection.So if you take viagra you do not want to be in a public place.ha ha ha

Fubar

I've been taking low dose Cialis (2.5mg daily) and I also have bigtime nightly erections. I've been on Cialis for about a week and I'm very happy so far. My pain has been getting a lot better and the daily better flaccid hang feels great and I think help reduce the pain as well. I think that as long as your feeling ok and not getting worse then don't worry about priapism.

I was having horrible headaches and muscle pain at first with Cialis but these bad side effects seem to be wavering. Let the good times roll:)

Is there a web site that anyone on the forum has actually purchased from and recommends? I tried one that was recommended by someone and not having much luck with them.

You have to of course be very careful when you order online as there are some dubious sites out there. alldaychemist.com appear to be reliable, and I did once order cialis from bmpharmacy.com which was recommended to be by a member here (woodman). Both good options in my view.

Really... I hope I didnt get burnt... I saw my charge on my mastercard but havn't recieved anything yet. i'll let you guys know when I get it and whether they are legit.

Quote from: crashbandit on April 09, 2011, 01:26:40 PM
I've been taking low dose Cialis (2.5mg daily) and I also have bigtime nightly erections. I've been on Cialis for about a week and I'm very happy so far. My pain has been getting a lot better and the daily better flaccid hang feels great and I think help reduce the pain as well. I think that as long as your feeling ok and not getting worse then don't worry about priapism.

I was having horrible headaches and muscle pain at first with Cialis but these bad side effects seem to be wavering. Let the good times roll:)

Very similiar to my experience. Hang definitely improves and everything down there just generally feel healthier. Erections are more frequent and stronger and I get the feeling that it helps the other treatments I;m on. The recent positive cialis study is a bonus too. I had horrible bad ache for a week after I started on cialis, but now everything is fine!

I did receive my product from tabsmarket.com. The first shipment got lost, but the re-shipped for free and I did receive it.

http://tabsmarket.com/cialis.html (http://tabsmarket.com/cialis.html)

Cialis from alldaychem just seems like weak viagra. I would not recommend.

how are you guys taking cialis at 2.5mg? are you simply dividing the 5mg in half?

The pills come on a card at 2.5mg.  I started the regimen awhile ago and a daily dose was too much (too many early morning erections).  So I take it every other day. 

However, I think viagra gives a firmer harder erection than the 2.5 cialis. 

The tabsmarket site is what I used as well.  Great pricing and the stuff works just fine!

Quote from: skunkworks on April 19, 2011, 09:00:45 AM
Cialis from alldaychem just seems like weak viagra. I would not recommend.

I've never had any problem with it. Has anyone else had a similiar experience? The more views the better!

Quote from: blackseal on April 21, 2011, 03:18:49 PM
The tabsmarket site is what I used as well.  Great pricing and the stuff works just fine!

I'd never heard of them, but good for people to have a new option..

The nightly erections are great with my 2.5mg daily dose. But I've been having big problems with flushing really bad. I've always had a problem with flushing before but not to this extent. When I first started pentox 6 months ago, the flushing got bad at times while drinking only but since adding cialis, the flushing is bad all the time now. So I'm cutting the cialis back to only 2.5mg every second day now.

are you guys taking cialis just before you go to bed at night?

Quote from: lespleen on April 22, 2011, 06:45:28 PM
are you guys taking cialis just before you go to bed at night?

You can take it whenever you like (just take it with food). The drug takes effect in about an hour then last for 36 hours.

I take the Cialis in the afternoon usually.  I assume it builds up and continually keeps working.  I have had no issues with flushing with the Cialis, with the small dosage.


ymn

Last two days seeing reports on so called "rapid hearing loss" for Viagra users.  Was pretty vague about other related products.  Anyone with any further info on this?   I'm using Cialis at the moment.

I wonder if these issues are more common with viagra than other erectile dysfuntion drugs. If there appeared to be a pattern with a specific drug, then it could result in people swithcing over to a different one. I haven't heard too many reports on here from people suffering from hearing problems, but it is something to think about in cases where ED is mild and supplement alternatives would suffice. Topical viagra is in the works I believe. That could also be a way of minimising side effects. I doubt it'll see the light of day for a few years yet though.

Lately my erectile dysfunction has had one of its severe flare ups, and there seems to be more scarring. I usually take 5 mg of Cialis, but have upped the dose to 20 mg so that I can get (with lots of effort) a partially full erection, because I know it's necessary for a healthy penis. However, when I get an erection, it burns -- not horribly so, but it's somewhat painful. Does the pain mean I should try to avoid artificial erections? I want to make sure I get enough bloodflow down there, but I also don't want to damage myself.  ???

I dont know about the pain... But be carefull!
I do not think you should take 20mg of cialis per day!!!
Cialis works for 36 hours. so you could get an "overdose"
I would go and see an andrologist/urologist. Ask him about the cialis and he can certainly help you with ED.
Luc

does cialis once a day dissolve plaque/scar tissue? anyone have any improvement?

iv been taking pentox bought 90 bills been taking it half way done know, not noticing any big improvements though. my uro wants me to go on once a day cialis im gonna try that out tommarow.

i dont understand how improved blood flow is supposed to dissolve plaque/ scar tissue.

90 pills that is one months dose? Really the damage and time measure depends on individuals.In my own treatment it does work takes more time. You may still not like the outcome but it does work.

Fubar

Only xiaflex disolves scar tissue. Pentox and cialis could help the body repair naturally but more research is needed. 

xiaflex is better than vepramil am i right?

Vepramil does not disolve scar tissue but helps stop it from forming. That is the idea anyway. In the inflammation stage it could be possible to stop a permanent scar forming. The idea of xiaflex is to soften or breakdown the scar after it has formed. This is also the idea. We have to wait and see how the trial goes. My uro says it is promising. I trust him.

agent

Cialis inhibits PDE5 (phosphodiesterase type 5) the chemical that reverses an erection.  None of the Big Three Erectogenics were developed for, nor do they claim collateral effectiveness in treating scaring.

I developed Peyronies Disease after taking Cialis for 3 years.  Do I blame Cialis for causing Peyronies Disease? NO!  I continued to use Cialis until it failed then I made arrangements to get implanted.  I have never discovered the cause nor have I found an effective treatment (other than a Prosthesis), however, some men have been treated effectively with less radical, more traditional means.

This insidious disease does not give up answers very often.  Keep reading and keep searching and you will find your solution.

i've been taking cialis now for about 3 months......i honestly feel that it's helping quite a bit......how long will this go on for......i mean when do we stop, 3 months, 6 months , a year????

Is the Cialis working as strong as the day you first started taking it? I noticed that after about 3 weeks of taking 2.5mg every 48 hourts, the effects started to wear off. Did this happen at all with you lespleen?

I'd keep using it if it seems to be working. I think it helps because you can really feel the extra blood flow and porn star flaccid hang as well. If I am taking the cialis, pentox and have a couple drinks, I get major flushing in the face. So this is evidence to me that the blood vessels are definitely being dialated. Hence, no Nitrates with cialis, as it can drop the blood pressure too much.

Should low dose cialis be involved in all peyronies treatments? regardless of age or if you have ed or not.

I am taking low dose cialis and I have no problems with ED (knock on wood). I have constant flaccid pain with a fllacid twist to the left The flaccid twist and pain is more prominant after ejaculation. It seems while I'm on low dose cialis, the pain is reduced. It just seems the cialis keeps my penis more pumped up during flaccid hang.

I would say cialis helps circulation, which can potentially remove scar tissue and speed up healing. I have heard of a few studies that can back this up aswell. My advice would be to try the cialis (even the 2.5 mg low-dose if you don't have ED) and see how it goes. It sure helped me feel better. 

truth be told i've been on 5mg every day!!!!! that's what they've given me here in france.....maybe i should take it every other day.....Regardless, no i haven't noticed a reduction in its effectiveness......maybe i'm taking too much......i could definitely stand to reduce blood pressure though.....you've been battling this thing for almost a year now? things improved but now the same pain has moved to the opposite side in the same place!!! lol.....if i have sex with my girlfriend more than 3 times a week things worsen....it's weird sometimes sex actually helps to calm inflammation sometimes it generates inflammation ....think i'll take the 5 mg every other day. but i honestly believe this cialis stuff is helping .......just so darned expensive. What i'm noticing is that the reproductive sciences are in a sorry state generally.....so we shouldn't be surprised if little progress has been made regarding peyronies. I haven't pulled out the  VED again yet. I'm really convinced that thing caused more harm than good. I've been on pentox for almost a year( in october)!!! For a while there it felt like every 6 months some new advance was made in peyronies treatment modalities....things have tapered off a bit. good luck,man.....you're right we should just stick with this cialis thing. I'm gonna reduce my intake...however, maybe you should increase yours? Cialis is an enzyme inhibitor ....perhaps this method of action is one which precludes long term habituation as a possible cause of reduced effectiveness........you may just need to up the dose a bit without fear that your body will once again habituate minimizing the effects.....What other stuff have you added to your regimin??

Hey lespleen,

Yep, 1 year almost since the first day I noticed something wasn't right and my dick felt cold at the glans and had alittle stinging feeling around the glans too. Yea, 5mg of cialis everyday is too much, especially for someone without ED. It is very expensive too. 90 bucks for 14-5mg tabs for me here in Canada. I've tried ordering off an online comapany but never got the Cialis and they refunded my money. Has anyone ordered Cialis from India at a much reduced cost? I think I'll start a new thread about that.

I find sex does help sometimes too with the pain and keeping my penis feelign nice and plump. It seems during the "shrinkage phases" I go through, the pain is the worst. I got 2 appointments in Septemeber with an Uro and a sexual medicine guy. Hopefully they can diagnose me with something. 

I've added numerous pills and ptoions to my regime in my fight against pain and flaccid twisting (I have no lumps or erect curvature). I've always taken my pentox and fish oils everyday and I'm try adding some type of something else (alc, astaxanthin, vit D, Vit K, magnesium, ubiquinol). But it's so hard to tell if any of these are working because my pain comes and goes on it's own... I've also added Celebrex once a day until I finish my bottle of like 30 or something. The Celebrex seems to have really help combat my recent pain flare up which is almost non-existant for the past few days (knock on wood!)

I second that.  The combo of low dose daily Cialis and the pentox has made me much improved.  I can barely feel the plaque lumps anymore, and my length and straightness have improved.  Also, fuller harder erections.  Not where I used to be pre-Peyronies yet though.

I've had the disease now since i was a22 so it's been almost 10 years. The first episode took about   1 year and half to 2 years to clear up and stabilize so hang in there. i've never had lumps or erect curvature either. Let me know what your euros/sexual medicine guys have to say given the similarity in our symptoms. I wonder if the cialis tablets can be split in half?

Yea, our pain definitely sounds similar but I gotta say I hope I'm not dealing with this as long as you did and still do. I should say I don't have no curve, I have flaccid curving/twisting, do you get the twisting while flaccid?

Expecially after ejaculation? After I let one blaze, I get a flaccid twist that cranks at a 90 degrees, so my glan top is facing completely to the left. And of course the pain also peaks after ejaculation and continues to peak for at least a few hours. Blows big time. It seems to be not so bad lately but sometimes it pretty bad and I almost want to cry. But then I think to myself, I guess it could be worse, which it definitely could be.

Cialis breaks easily with your fingers in half. Or just get a really sharp knife and split it with that. I recently got a 10mg tab of Cialis off a friend and easily split it into quarters with a paring knife. Razor blade would work great too.

I'm let you know what those 2 Uro's tell me for sure.

Hey Guys:

FYI, there are pill cutters available at most drug stores and health food/supplements stores. They are very cheap and do a very good job of splitting pills anyway you desire.

Old Man

Pill splitting works great highly recommend you getting one.Makes the entire process more manageable. Less management always does.

Fubar

I don't see the point of using a pill cutter for myself. I can easily cut a cialis tab in half with no waste and very accuratly. I can even do it in quarters. But I guess if you are doing percise small cuts then a pill cutter is needed.

Wow,  awesome response or a waste of words.

http://www.peaktestosterone.com/Cialis_Long_Term.aspx

interesting link to a website that talks about the pro's and con's of long term cialis use ... seems to be backed up by studies quoted at the bottom of each page ... on the whole reads pretty positive ...

There is one study out there which suggests that cialis may help with certain kinds of penile scarring. Whether ir has useful applications for us in that regard I do not know. I personally think that pentox and cialis might be a good combo.

One uroligist i saw said that it helped in straightening the penis also went and retrieved a book when i mentioned xiaflex.Told me to comeback if i needed surgery.The thought process of theese guys i have yet to understand?

Fubar

Quote from: lwillisjr on April 18, 2011, 10:09:55 PM
I did receive my product from tabsmarket.com. The first shipment got lost, but the re-shipped for free and I did receive it.

http://tabsmarket.com/cialis.html (http://tabsmarket.com/cialis.html)

Well, got a call from my local pharmacy and they said my insurance will not cover Cialis anymore.  They didn't pay much anyway.  My prescription is for the low dose 2.5mg daily since that was what was used in the Cialis study that showed improvement in diminishing penile scars.  However, I see that tabsmarket does not offer the low dose daily.  Any other recommendations from anyone?  I will be paying out of pocket, and am looking for a better price.

I just received my first order of generic cialis from alldaychemist.com.

However, I believe it's for the larger dosage, I think either 10mg or 20mg which I will cut down to about 5mg and use every other day.  I just received notice from the post office, but I haven't picked it up yet and I can't recall whether it's 10 or 20mg.

And, I'll let the forum know what my opinion is on it's effectiveness.

So, I ordered online; received several email confirmations about order, shipment and tracking; it arrived in about two weeks; according to the website, the product was manufactured in India.

CF

Retail medicines in India have "MRP Rs XXX" marked on the blister packs.  This means the manufacturer's recommended price is XXX Rupees for the single blister pack.  By shopping the internet aggressively, you can find Tadalafil for less than some Indians pay for it.
The 20 mg pills are the most economical.  I cut mine into 8 pieces.  Some brands crumble more than others, but I always slip my approximate 2.5 mg dose into a gelatin capsule since the exposed Tadalafil tastes very bitter.  Empty #3 capsules cost less than a penny each when bought in quantity.   

I read on the official Cialis company website to beware of online sources selling generic.  It says there is no generic form of Cialis.  I'm sure this has been discussed before. 

Quote from: restore on December 02, 2011, 11:19:22 PM
I read on the official Cialis company website to beware of online sources selling generic.  It says there is no generic form of Cialis.  I'm sure this has been discussed before. 

There are at least four big Indian manufacturers of tadalafil pills: Ranbaxy; Cipla; Dr. Reddy's; and Cadila.  One is even listed on the NY Stock Exchange.  If Lilly USA holds a patent on tadalafil I don't know how the Indian companies get around it.

Tadalafil is tadalafil is tadalafil.  If you get the Indian tadalafil it will work just like the Lilly tadalafil.  But all drugs may be counterfeited. Therein lies the danger for the buyer passing his real money to a cyber dealer.  Pick one that has been in business for more than a year.

ppain,

I believe you've made the credited response!  I agree.

CF

Has anyone been on Cialis now for at least a year's time? Wondering about side effects and the practicality of continued daily use over extended periods of time. Cialis has done me more good than some of the other treatment modalities but i doubt that i can continue like this for the remainder of my 30's.

VED is a good instrument also to improve erections.

Yes cialis is the best out of all of them expecially for peyronies disease. You take pentox and cialis and your golden compared to before. viagra didnt even work for me but cialis is great.

I had 2 months of cialis from the doctor and my erections greatly improved im on pentox twice a day 400 mg and was taking cialis 5 mg. I ran out after 2 months and was supposed to see my doctor but there was a snow storm and couldnt make it cant wait to see him again so I can get more and try and increase the dose it works wonders.

I have the Cialis really throttled back to 2.5 mg (20 mg cut 8 ways) only 2X per week. That seems to be enough to wake everything up and stay under the headaches side effect.  I am not sure what daily use will do in the long run.

Quote from: Iseilinus on February 21, 2012, 09:23:12 PM
I have the Cialis really throttled back to 2.5 mg (20 mg cut 8 ways)

I am wondering how you do that.. I have enough problems cutting cialis (drop shape) in 4 ... Do you have a special tool to cut into 8?
Would be interesting, because I think even when cutting into 4 I still dont get equal parts. (due to the shape of the pill)
Luc

Hi Folks.  I am on my third day of cialis 5mg.  I have read quite a few posts indicating nocturnal erections and erections experienced during the day.  I am not experiencing these.  In fact, I am only noticing a minor change in my erection quality since starting on the cialis.  I bought the cialis from a pharmacy up here in Canada and it is not generic.  I have been taking them in the morning.  Please advise, does it take time for the full effect; i.e. will I notice more effect within the next few days/weeks?  Or has the experience been that it takes effect within the first hour of the first time taking it?  Thank you.  Anthony.

If you take cialis, it does not meen you will get errections all the time. This is not the way it works.
Even with cialis, at any dose (low or high) you will only get an erection if you are sexually stimulated.
(its the same with viagra and levitra)
To simplify, if you get an erection, cialis will sort of prevent the blood from leaving the penis to quickly. So you will have a harder and longer erection.
But if are not sexually stimulated YOU SHOULD NOT get an erection!

As for the dosage, lots of us take cialis at 5 mg. Having better erections is a nice side effect, but the main reason is, that they have been studying rats, and the penises of those rats seemed to heal better after injury, than those that didnt take cialis.
So they found that all of those PDE5 inhibitors had antifibrotic properties. So it seems (there is no real proof) that it can help with Peyronies Disease.
AND as lots of people beginn to have ED when getting Peyronies Disease, the fact that more blood comes into the penis can only be a benefit.

I doubt though that you will really notice a big difference while having sex with 5 mg a day (although every person is different). If you have real ED and get cialis prescribed for intercourse, then usually doctors prescribe 20mg. The 20 mg should last for 36 hours, thats why it is also called the weekender pill. But the 20mg dose should NOT be taken on a daily base.

When you take cialis, the effect will come after one or 2 hours, depending if you had food or not, alcohol or not. Food and alcohol slow down the effect.
If you take it for intercourse, they suggest you take it on an empty stomach, at least one hour before intercourse.
Usually, people take it at night, because they have a date that evening.
If you are very worried, (that is normal when you are diagnosed Peyronies Disease) then even with cialis nightly erection can be very rare.

Luc

Quote from: Luciano on April 26, 2012, 01:38:59 PM
If you take cialis, it does not meen you will get errections all the time. This is not the way it works.
Even with cialis, at any dose (low or high) you will only get an erection if you are sexually stimulated.
(its the same with viagra and levitra)
To simplify, if you get an erection, cialis will sort of prevent the blood from leaving the penis to quickly. So you will have a harder and longer erection.
But if are not sexually stimulated YOU SHOULD NOT get an erection!

As for the dosage, lots of us take cialis at 5 mg. Having better erections is a nice side effect, but the main reason is, that they have been studying rats, and the penises of those rats seemed to heal better after injury, than those that didnt take cialis.
So they found that all of those PDE5 inhibitors had antifibrotic properties. So it seems (there is no real proof) that it can help with Peyronies Disease.
AND as lots of people beginn to have ED when getting Peyronies Disease, the fact that more blood comes into the penis can only be a benefit.

I doubt though that you will really notice a big difference while having sex with 5 mg a day (although every person is different). If you have real ED and get cialis prescribed for intercourse, then usually doctors prescribe 20mg. The 20 mg should last for 36 hours, thats why it is also called the weekender pill. But the 20mg dose should NOT be taken on a daily base.

When you take cialis, the effect will come after one or 2 hours, depending if you had food or not, alcohol or not. Food and alcohol slow down the effect.
If you take it for intercourse, they suggest you take it on an empty stomach, at least one hour before intercourse.
Usually, people take it at night, because they have a date that evening.
If you are very worried, (that is normal when you are diagnosed Peyronies Disease) then even with cialis nightly erection can be very rare.

Luc

Thank you for your response Luc.  I appreciate your insight.

The erections I was referring to were when I was sexually stimulated.  I notice that they are a bit better, but not much.  I am waiting to see a Peyronies Disease Uro, but am pretty sure I have Peyronies Disease, from what I have read and the fact that it is curved.  Along with the curve, my symptoms have also included a loss in erection quality (ED).  I was of the understanding that cialis would help with this quality issue and, by way of the bloodflow increase it provides, also help with addressing the Peyronies Disease.  I have read many members posts wherein they discuss nocturnal erections.  If it is not the cialis/viagra that is providing for these, then please may I ask, what is?  The PDE-5 inhibitor meds are marketed as help for ED, so I assumed I would notice a more significant difference.  Especially given what we pay for them.

My hopes are that, through diligence and addressing this early on (it has only been 6 weeks since I noticed the curve), I will regain erectile strength and reduce or at least halt the curving. 

Might other forum members please care to also share their insight?

Thank you, again Luc.

Anthony

There is research indicating that LOW DOSE Ciallis actually helps repair Peyronie's damage (just like Pentoxifylline does, but not so much).  But LOW DOSE Ciallis is prescribed for Peyronie's, NOT for ED.  If you really need BOTH benefits, you will probably need to get a new prescription for a higher dose of Ciallis.  - George

Anthony,

I am in a very similar situation to you. I get nocturnal erections which are much firmer than at any other time. Like you, I must admit this confuses me (if there's a blood flow problem why does it not happen at night is the question).

I don't take any medication because I'm very wary of anything that interferes with blood pressure. I was wrongly diagnosed with high BP about 4 years ago and the doctor put me on Captopril. One single dose nearly killed me. My BP went through the floor. The doctor decided that I had 'white coat hypertension' which was confirmed when his head nurse took my BP and it was fine.

I'm also interested in the views of others.

Quote from: anthonycann on April 26, 2012, 03:37:48 PM
The erections I was referring to were when I was sexually stimulated.  I notice that they are a bit better, but not much.

I agree 100% with George! 5mg is low dose. 20mg is for better erections. Try it, but dont overdo it. I repeat: 20mg is NOT for daily use, unless prescribed otherwise by your doctor!!!
Luc

Thank you for your responses. 

My GP originally prescribed 20mg cialis with the intent that I would take it every third day.  Am I understanding correctly, that this would still provide the benefit of the aid to the Peyronies Disease repair while also providing for erection strength?  Having read throughout the forum that 5mg seems to be the norm, I asked him to change the prescription.  I only bought a 30-day supply, so I could always request a change to the 20mg cialis.  Is 20mg every third day too much?

I would think that you would get both benefits with a higher dose taken on an as needed (NOT daily) basis.  - George

New member to the Viagra, Cialis, Levitra familly.

I am quoting bellow from Fox News:

QuoteFDA approves Vivus's fast-acting Viagra rival

QuoteMen with erectile dysfunction may not have to plan for sex as far in advance anymore after Vivus Inc won U.S. approval for avanafil, its faster acting rival to Viagra.

Avanafil, which will be sold under the brand name Stendra, is the first new drug in the category in a decade.

The drug -- which will compete with Pfizer Inc's Viagra, Eli Lilly's Cialis and Levitra, sold by GlaxoSmithKline and Bayer -- gives Vivus, which has struggled to bring a weight loss drug to market, a potentially lucrative commercial product.

The Vivus drug will have some attractive marketing claims as it goes up against established rivals sold by companies with serious marketing muscle.

"This is potentially the fastest acting of the four," said Dr Wayne Hellstrom, professor of urology at Tulane University School of Medicine in New Orleans.

While it is recommended that patients take the new pill 30 minutes prior to sexual activity, in clinical trials it has been shown to work in as fast as 15 minutes. Viagra typically takes about an hour to start working.

Stendra belongs to the same PDE5 inhibitor class as its rivals and also works by increasing blood flow to the penis. But researchers found it to be more selective than the older drugs, meaning it could have fewer unintended effects.

"Higher selectivity should translate into fewer side effects," said Hellstrom. "It's going to add more excitement" to the field.

ED afflicts as many as 30 million men in the U.S., Vivus said. The Vivus drug is currently awaiting a European approval decision.

Cowen and Co analyst Simos Simeonidis, in a research note, forecast annual Stendra sales of about $300 million. Viagra had sales of about $2 billion in 2011.

Vivus shares were up about 3 percent following the expected approval by the Food and Drug Administration. Investors are far more focused on the prospects for Vivus's obesity pill Qnexa, for which the FDA is expected to rule by mid July.

Doctors should prescribe the lowest dose of Stendra that provides benefit, the FDA said. It has been approved at doses of 50 milligrams, 100 mg and 200 mg.

"This approval expands the available treatment options to men experiencing erectile dysfunction, and enables patients, in consultation with their doctor, to choose the most appropriate treatment for their needs," Victoria Kusiak, deputy director of the Office of Drug Evaluation in the FDA's Center for Drug Evaluation and Research, said in a statement.

The most common side effects reported in clinical studies included headache, flushing of the face and other areas, nasal congestion, common cold-like symptoms and back pain.

The drug carries the same cautions as its rivals, including that it should not be used by men who also take nitrates due to the potential for a sudden dangerous drop in blood pressure and the now famous warning to see a doctor if an erection lasts more than four hours.

Vivus shares, which closed up 2.9 percent at $25.15 on Nasdaq, rose to $25.40 in after hours trading.

Read more: http://www.foxnews.com/health/2012/04/30/fda-approves-vivus-fast-acting-viagra-rival/#ixzz1tWvtkyQj

I will merge this topic later with Viagra, Cialis, Levitra topic.

James

Quote from: cowboyfood on December 02, 2011, 01:34:50 PM
So, I ordered online; received several email confirmations about order, shipment and tracking; it arrived in about two weeks; according to the website, the product was manufactured in India.
CF

Cowboy -- how was the effectiveness? Would you order from here again? Does anyone else have recommendations for Cialis online, low(er) cost?

IMO, very effective. 

I'm taking about 5mg every day, or every other day.

I ordered the 20mg tablets and have been "cutting" a tablet into four pieces. However, cutting one tablet into four pieces can be tricky and I usually mess it up.

So, I plan on ordering from the company again very soon, but I will order their 10mg tablets and just cut the tablet in half.  This should be much easier.

CF

A useful comparison of Cailia, Viagra and Levitra: http://img30.imageshack.us/img30/5499/versusi.jpg . It's possible that I posted it before, but don't think I have.

newguy

I would like to read the comparison, but:
The link bring me to http://imageshack.us/img/blocked_login.jpg (http://imageshack.us/img/blocked_login.jpg)
A picture of a frog in an ice cub. I like them fried.

James

I wonder why it's blocked from your location? I have attached it to this message. Basic info really. Not peyronie's specific, but I figured it might be of use as a quick overview..

Newguy, thanks for the information.
Where I am living now they are blocking even some videos regarding dogs or yachting.
Basically is connected to Peyronies as many of us using them for erection or daily dosage.

I am blessed to have all the side effects from Viagra and Cialis, I didn't try Levitra.
I have to mention that after using for two weeks the daily dosage of 4mg Cialis or the daily approx. 15mg Viagra the side effects disappeared, still 20mg Cialis or 50mg Viagra have the side effects.

James

Where I am they only block content related to kittens and mittens j/k.

I'm in a similar position. I've never tried Levitra but have the other two. Viagra gives me indigestion and a blocked nose. The first time I took Cialis I had really bad back pain. After that though, it was fine, even when I only took it sporadically. Personally viagra gives me stronger erections, but Cialis provides a decent boost over a longer period of time, as it to be expected. Pycnogenol and L-arginine worked pretty well too, but the combination made the roof of my mouth really itchy (odd, but true).

Suddenly the Internet is being blocked left and right and the people you can thank for it are the big media corporations that are forcing these ill conceived censorship efforts in order to try to reign in IP piracy.  Of course it won't be effective, the REAL pirates will always find a way around it, but you and I will suffer and they block in this direction and that, blocking legitimate data in order to try to increase their already outrageous profits.  - George

The new guy in town udenafil marketed under the name Zydena
So we have now 5 friends for ED: Viagra, Cialis, Levitra, Vivus and Zydena.

Zydena® is currently marketed in Korea and Russia

http://www.medicalnewstoday.com/releases/171452.php

James

I took them all levitra, cialis and viagra the best for peyronies is cialis by far i dont care what anyone sais from experience. from cialis i havent noticed any side effects and from viagra i got headaches.

When I was at my local urologist a couple of weeks ago I noticed a pamplet for Zydena. I read it and it is the same class as the other ED drugs. I would assume it is now available in the US.

Jackp
http://jackp-penileimplant.blogspot.com/

I'm not a spammer, but I need recommendations on a place to buy quality Cialis (or generic).  I'm concerned with safety, but care a bit less about legality and grey market issues.  I just got denied by my insurance and it looks like Cialis at my present rate will cost me about $150 a month.  That's ridiculous.

Suggestions welcomed, preferably nothing China or India.

I will suggest:
https://www.riverpharmacy.ca/drug/cialis
They don't have the 5mg, I bought locally where I am living now the 20mg and cutting it in 5 pcs.
I bought from Riverfarmacy Pentox, they are OK in my opinion.

James

How easy are they to cut?  Are they generics? My 5mg's are easy to cut, but you have to be careful so they don't crumble and getting them even is a little tricky.

Quote from: james1947 on August 28, 2012, 06:16:38 PM
I will suggest:
https://www.riverpharmacy.ca/drug/cialis
They don't have the 5mg, I bought locally where I am living now the 20mg and cutting it in 5 pcs.
I bought from Riverfarmacy Pentox, they are OK in my opinion.

James

I don't know if they are generic or not. You may email them and ask.
Because they shape, the cutting is quiet tricky.
I am using a sharp and relatively heavy short knife, placing the knife on the place I want to cut and make a sudden push. Not always the same size, but is OK. I can make 4 or 5 pcs from the 20mg Cialis pill, so it is reducing very much my monthly cost, very important for me as I don't have insurance also and I am not a wealthy man as well.
I know that in many places in the world you can buy in the pharmacy a pill cutter, where I am living now I didn't find.

James

James, I'm in the same boat.  Been paying $160 a month at CVS since my Blue Cross won't pay for it.  They won't cover any drugs marketed for any sexual disorders.  BUT, if the medical world would ever expand the purpose of these drugs as also to treat other diseases such as Peyronies, it may be covered then.  I know of one study that showed good results with Peyronies taking daily use Cialis, but there may have to be more before it will be approved for it.

Quote from: JamesW on August 28, 2012, 06:09:54 PM

Suggestions welcomed, preferably nothing China or India.

Actually the generic products (cialis but also many other prescription drugs) made in india are very good quality.
There are huge production plants and big pharceutical companies have their medications produced there.
Usually, these indian companies sell their products legally in countries not having signed the patent agreements.

These products are safe. (of course there are indian companies that are good, some are not.)

I'm not saying buy indian, but do not,  not buy just because its from india.

Luc

Check out River Pharmacy.  They are an online drug store I've been using for a couple of years now and I've never had any complaints.

GS

Hi

I have a few questions about Cialis. My pharmacist gave me a box of 30 pills of 5mg each. I was wondering is it best to take 5mg or 2,5 mg daily? each tablet has a day on it (monday, tuesday) is this of any importance? (this might be a very stupid question, i am just cautious with all these kind of medication)

thx in advance,

Alex

Quote from: anthonycann on April 26, 2012, 10:17:46 AM
Hi Folks.  I am on my third day of cialis 5mg.  I have read quite a few posts indicating nocturnal erections and erections experienced during the day.  I am not experiencing these.  In fact, I am only noticing a minor change in my erection quality since starting on the cialis.  I bought the cialis from a pharmacy up here in Canada and it is not generic.  I have been taking them in the morning.  Please advise, does it take time for the full effect; i.e. will I notice more effect within the next few days/weeks?  Or has the experience been that it takes effect within the first hour of the first time taking it?  Thank you.  Anthony.

If you are not getting much effect from cialis after taking it for awhile, it is time to get your testosterone levels checked.

alexsisserieus

It is not a stupid question.
The Cialis daily dosage was prescribed by a doctor?
I don't think the day have some importance except to make follow up more easy and not to forget.
From what I know from the forum, 2.5mg daily may be enough for treating Peyronies, 5mg daily helps with erection.

James

My new urologist has prescribed Cialis and Pentox for me last week and I started Cialis last Thursday but had to wait to today before Pentox was available at my pharmacy.


For the first two days I had no negative side effects from Cialis then on Sunday morning I had some crazy back ache that later extended to my legs. Lower back ache isn't an entirely new experience to me but the leg pain was so I suspected Cialis was the cause and sure enough that appears to be the case looking at the listed side effects on their web page. Since Sunday morning the pain has been coming and going in my back and legs but it's present most of the time and I'm finding it really hard to concentrate on my work or even sleep. It's 4.10am here now and I woke up two hours ago from the pain.


When the pain kicks in I've found that going for a walk seems to help as long as I keep moving but I'm not about to do that at this time of night and I suppose I could try some more ibuprofen but I'm reluctant to keep taking pain killers and really hope this will go away soon or I'll go nuts.

Ashtown

I had experienced also back pain that radiates to my legs in addition to flushing (like my face was burning) and excessive sweating. I reduced the dose to 2.5mg and within three weeks my body get used to and the side effects as well. I am taking now 4mg daily (in the evening) and everything OK except the flushing, but not so strong and for short time (about 30 - 40 minutes).
Try to reduce the quantity until your body get used to.

James

Thanks James, At around 5.30am this morning I finally gave up the battle and took a couple of ibuprofen, then 20 minutes later I was asleep. It's now almost 6 hours later and I have practically no pain so I think I'll keep an eye on this and see if I can handle the 5mg without too much stress in the short term while my body is getting used to it but if necessary I'll break the table in half and slowly increase the dose.


I ordered some more L-Arginine from Amazon but they've taken ten days just to dispatch an item that was already supposed to be in stock, so I really hope it arrives today/tomorrow because I basically ran out on Sunday, which is when the pain kicked in from the Cialis and I wondered if that might be connected, since the Cialis gave me no problem at all for the first two days.

ashtown - I had that exact same problem with Cialis initially. It was a feeling like I've never felt before right in my lower back area. A very uncomfortable ache. Thankfully after a week of taking Cialis it went away and I never experienced it again (even when, I stopped taking Cialis for a while, then started back again). Hopefully that will be the case for you too. If not, there's always Viagra.

I'm monitoring this so I don't want to say anything yet for certain but in my case I think the pain from Cialis is largely cancelled out by L-Arginine. When I first took the Cialis I was on 2g per day of L-Arginine and I never felt a twinge but when the L-Arginine ran out the pain kicked in about 12 hours later and it was heavy going affecting my lower back, legs, sides and even arms at times.


Today the pain was starting again after the ibuprofen started to wear off but then some more L-Arginine arrived so I took some immediately and within half an hour the pain started to subside. Then I took my daily dose of Cialis at 6.00pm and within 15 minutes the pain started to kick in but minutes later it subsided again presumably because the L-Arginine taken at the same time was also taking effect. At the moment I'm not in too much pain unless I try to stretch like touching my toes which is still hard at the moment and it almost feels like I have a trapped nerve in my back. Normally speaking I can touch the ground with the palms of my hands.


Perhaps I'm just slowly getting used to Cialis and my body is adjusting but I am just wondering if there is something in this L-Arginine connection. Whether it's L-Arginine or just a natural adjustment I hope this pain starts to go away completely before long. 

Quote from: alexsisserieus on September 09, 2012, 08:19:44 PM
Hi

I have a few questions about Cialis. My pharmacist gave me a box of 30 pills of 5mg each. I was wondering is it best to take 5mg or 2,5 mg daily? each tablet has a day on it (monday, tuesday) is this of any importance? (this might be a very stupid question, i am just cautious with all these kind of medication)

thx in advance,

Alex

Alex,
It's mostly a way to keep track of when you have taken your medication. And 5mg is the stronger dose. I would suggest you try cutting them in half and trying 2.5 mg dosage. If this works for you then your meds will last twice as long.

Quote from: james1947 on August 29, 2012, 12:17:34 AM
I don't know if they are generic or not. You may email them and ask.
Because they shape, the cutting is quiet tricky.
I am using a sharp and relatively heavy short knife, placing the knife on the place I want to cut and make a sudden push. Not always the same size, but is OK. I can make 4 or 5 pcs from the 20mg Cialis pill, so it is reducing very much my monthly cost, very important for me as I don't have insurance also and I am not a wealthy man as well.
I know that in many places in the world you can buy in the pharmacy a pill cutter, where I am living now I didn't find.

James

I use a single edged razor blade (like this: link (http://www.mcmaster.com/#single-edge-razor-blades/=jmd0kt)) successfully cutting 20 mg Tadalafil (Cialis) into 8 pieces.  I tried a cute pill cutter which did it worse.  I put the Tadalafil pieces into very small gelatin capsules (5mm x 17mm) which are extremely cheap when bought in quantity.  When I visited India I brought back about 6 different brands of Tadalafil.  (Some, but not all, pharmacies there sell them OTC.)  They varied in price by more than a factor of 1.5.  I've noticed no differences in efficacy among the brands.  One difference for our purposes is that some crumble under the razor blade much more than others.  Ranbaxy brand crumbles hardly at all.  My method has been to take about 10 pills to make about 80 2.5 mg capsules.  For the most crumbly brands, after about 50 capsules with single hunks I start making capsules with multiple bits, and the last 10-15 capsules receive crumbs.  It's not much trouble and a pleasant ritual in contemplation of how the Tadalafil will be used. 

I use alldaychemist when I need "generics". Something odd happened when I took some generic Cialis for a while - my hearing deteriorated and I started getting tinnitus. Oddly, that's a side effect associated with viagara, but not cialis. I mentioned this to my doctor and he said maybe it was contaminated with heavy metals. I'm back on the name brand stuff for now, and my hearing is going back to normal.
I bought the absolute cheapest stuff at alldaychem. It's called Ceebis and it's made by Cooper Pharmaceuticals. I think maybe sometimes you get what you pay for. Granted, I'm gonna be buying more generic taladifil, but next time I'm gonna go with a more reputable pharmaceutical company like Ranbaxy or Cipla.

I bought Cialis from same source as Pentox:
https://www.riverpharmacy.ca/drug/cialis
I don't have any connection to them, just a customer!!!
They don't stock the 5mg. I am buying the 20mg, cutting to 5pcs. Come out $0.25 per day

James

I am 2 months into a 6 month run of 2.5mg cialis every day. Obvious increase in erection frequency and strength, hope to report back about the effect on scar tissue in 4 months.

Started on 5mg of Cialis 4 days ago. I also take Pentox, Ubiquinol, ALC and L'arginine. Can the L'arginine be dropped now in favour of the Cialis or do they work in different ways?

Sorry if this has been asked before.

LMP, personally, I take the Cialis and the Arginine precursor, Citrulline Malate.

They do work in different ways and not just for erections but for treatment doctors prescribe them together as the PAV cocktail for Pentox, Arginine, Viagra.

As others have observed on here - since starting Cialis, definite backache and a bit of earache. Slightly better today so I'll keep going and hopefully build up some tolerance.

I only ever took Cialis a few times.  I took a maximum dose for ED not a daily maintenance.  Each time I felt like someone had hit me across the lower back with a baseball bat.  I have asked about the physiology going on with the back ache with this one ED drug and I have never gotten an answer.  I MUCH prefer Levitra to Viagra or Cialis.  No back ache and no interference from food (fat intake).

Going to try and ride out the pain and hope it's just my body adjusting to it. More of a big discomfort today, rather than a pain. Plaque pain was worse yesterday too.

I notice the PAV cocktail get a lot of mention. The Pentox and Arginine are daily medications. But how can anyone possibly afford Viagra every day? I paid $150 for just 6 pills. Is the "V" of PAV a daily regimen?

I think the original prescription was 1/4 of a tablet daily which still is not cheap.

Now many take the Cialis low-dose daily tab.  I have no clue what that costs but I am sure it is also not cheep.

The generic cialis can be ordered online for 2.13 per 20mg tablet.  I split it 4 ways and take a quarter every 3 days (I dont have ED).  Total cost: 0.18/day Side effects diminish when taking the low dose long term in most people. 

Norm you can get the V for about the same price and split them but you would have to take it daily since the half life is much shorter vs cialis.

I'm on thyroid meds which means you get a exemption card and don't have to pay for any medication that's prescribed, even the non thyroid meds. The only blessing in this sorry affair.

can Viagra have dangerous side effects? I revived some from the VA last time I went get get my VED for Peyronies Disease and I cut a 20 in to many smaller pieces and with in an hour I was vary light headed and flush in the face, no erection difference but an over whelming feeling to go to sleep.

Please feel free to ask your doctor for samples> ask any of them and all of them
Drug companies pass out samples all the time. Believe it or not I get some from my uro and some from my endo.
If you never ask... remember the answer is always no.

I got 60 days supply of 5 mg. Cialis from my urologist for free. That was a good day. :)

By all means, ask for samples! My doctor has been providing me samples of Cialis for five months. I haven't bought one yet. I made the mistake of going out of town for a week w/o them. By the second night, the nocturnal and morning erections had disappeared. And I thought my penis was going to shrivel away! You can bet when I got home yesterday I took one straight away. At such time as I no longer get free pills, I will demand a prescription. That's what the drug reps are counting on.

I take Cialis 5 a day it works well and I like it better than Viagra.

I'm a 40 yrs old and recently diagnosised. I had my urologist prescribe me 5mg cialis tabs. Now I find out insurance only will cover 30 tabs in a 90 day period. Leaving a huge hole in my wallet. I'm going to try and appeal but in the mean time there is no way I can cover the cost. Does anyone have any suggestions? Maybe a good website or such.

A lot of the guys here use River Pharmacy and say it is reputable. Perhaps one of them will speak up with a testimony about it.

I have ordered many times from riverfarmacy.
Good products, fast response, reasonable prices.

James

PS. I am not affiliated in any way with riverfarmacy, just a happy customer.

I also was happy with river and there "tadacip" brand cialis pills (although I found cialis made my pain symptoms worse unfortunately).

I've bought 5mg cialis from India. 30 day supply was around $70. My ins won't cover cialis for me either at 43, so it costs me $150 out of pocket. I recently ordered 10mg cialis from River Pharmacy (they don't sell 5mg). Placing order was easy except you'll need to call them to finish your order. You can start the order online but then call to give your card number. They seem reputable.

I'll ask my PCP or urologist for a 30day supply when I'm there. They both seem to have it available in their offices. Or ask for a voucher which your pharmacy will honor

Regarding riverfarmacy:

Quoteyou'll need to call them to finish your order

They never asked me to call them, I fill the VISA card data online. Maybe because I am not in the US?

James

James, yes if you're in the U.S. you have to call to finish the order for some reason. The girl on phone already had my name/info & knew what I had in my cart. Just had to give her credit card #

This must be something new to prevent credit card fraud, I am in the USA, they did not call me.

You need to be extremely careful ordering from these so called Pharmacies.  I ordered some Cialis from one of them in 2009.  Then about a year later, someone was using my Card number and name on the Internet to purchase items.  My bank called me and asked me if I was buying these things.....of course I didn't.  The bank, fortunately, refunded my money and cancelled my card.  Then, ever since, I have been getting Spam type phone calls asking me to purchase Viagra or Cialis.  I really need some Cialis, but too scared to order from these websites. 

dplookin

I agree with you that have to be very careful with everything you buy online using your credit card, but here on the forum some members including me have very good experience with riverfarmacy. I am buying from them Pentox, Cialis and other meds not Peyronies connected, had never any problem.
By the way, in cases that the amount is more that $50 and some new source the credit card companies are contacting me before approving the transaction.

James

Can someone please provide the website address for River Pharmacy......Thank you.

https://www.riverpharmacy.ca/index.php

James

Thank you, James.  I thought that was the website.  I just wanted to make sure.

I'm more concerned with the health risks.  I've heard reports of these pills being everything but what you think you're getting.  Having said that though the pharmacy I go to wants to charge me $280 for 10 pills of Viagra which is obviously ridiculous.  Do they send these pills in the manufacturer's box so that you know it's legit?

The pills from river are generics.  There is no guarantees so I understand your hesitation.  However they are less than 2.00/pill if I remember correctly and we have been happy with the results.

Ahh, I see....I remember hearing about this actually.  Some dickhead judge in the US extended the patents for like another 10 years.

Well, for those that have tried this pharmacy, can you give some more feedback?  Do these generics make you feel different in anyway than the brand name?

Simply, NO, I don't feel different except that my pocket get less light.
Example:
Xiaflex (Trental) here where I am living now is $1.5 per 400mg pill, from riverfarmacy in big quantities is $0.16 per pill and free shipment.

James

Ok, I guess I'll give it a shot.

I just got a some 10mg cialis from river pharmacy. It was a no brainer. Mailman left it even though I was at work. It's generic version but I think it's same as prescribed cialis. It took under 2 weeks to receive it after ordering

Who makes it?

tadalafil 10mg or megalis-10

made in india by macleods pharmaceuticals.

Just FYI...........I orders some Cialis through a website a few years ago, and it came from India.  I found nothing wrong with this product, and it worked Great.  Don't think I would be afraid of using these products.  I would just be afraid that the wrong person would obtain my Credit or Debit Card number and start buying things with it.  Which happened to me.

Hey guys. Want to give a big thumbs up to the River Pharmacy suggestion. Received my shipment in two weeks. Ordered the 10mg Taladafil and am pleased with the product. Ordering was hassle free and was delivered to mailbox. Saved a bundle of money. Cheers!

Actually, that is good to hear.  When I get the Money, I should try the same.

Two years already I am buying my medications from them, they are just fine.
Delivery by post is cheep, sometimes they are sending free if you pass certain amount with your order, come to my door and paying ZERO import taxes ;D

James

I made my first purchase from River Pharmacy today.  Easy as Pie.  I did question them regarding the security of my Card Number, and they convinced me that everyone's Credit information is kept confidential and secure.  Consequently, I will buy from them again in the future. 

I bought from riverfarmcy a few times during the last two years, was never overcharged.
I will mention again, I am not connected to them in any way.
Just a happy customer. ;D

James

I might have missed reading it but do you need a prescription from a doctor when ordering from riverpharmacy?
THANKS

No Prescription needed.......Just Money

I get cialis now money is what I'm trying to save!
thanks

My PCP gave me a few 5mg cialis vouchers (30 day free supply). I tried to redeem it today and pharmacist shot me down because I used one a few months ago. I'm wondering if I'd have any luck with it at a different pharmacy. They had my on going script on file from my uro. My out of pocket cost is $150 for it. I know I can get 10mg through River online pharmacy, but I'd prefer to stick with the 5mg cialis.

Anyone have any suggestions or experience with this?

Maybe have a buddy fill it for me or would he need a script?

-Thanks

I've been able to use vouchers multiple times by switching pharmacies. Not for Cialis but other drugs. I don't see why it wouldn't work as long as you have a new scrip written up. Private pharmacies rarely share info.

The Cialis vouchers are only for 1 months supply and only one a year.

Jackp
http://jackp-penileimplant.blogspot.com

jackp or anyone else, do you know if the drug maker tracks the redeemers name on the voucher or does the drug store?

Cialis tracks the coupons. Once you redeem one it will be a year before you can redeem another.

Jackp
http://jackp-penileimplant.blogspot.com

Does anyone know if you need a script along with the voucher to use it? I have 3 valid vouchers which I could get friends to redeem for me if they don't need a script

STENDRA, the new ED drug from Auxilium
STENDRA™ (http://www.stendra.com/)

James

I understand that Stendra is like Cialis & Viagra, etc. but I'm hoping that it works differently enough to help me maintain my erection better. I can't wait till it comes out into the market. I'm looking forward to doing a lot of business with Auxilium.  ;)

Absolute best prices on cialis is from Evolution peptides. There are several peptides companies out there. A 30 ml bottle of 30mg per/ml solution is $30. Four drops equals 5mg of cialis That's the equivalent of 180 5mg pills. Do the math. 6 month supply for $30. Best thing is that it is a US company. No overseas companies to deal with and no scrips. Of course this product is for "research purposes non human consumption" only. I can vouch for the efficiency of their products.

My only experience with erectile dysfunction medications has been with Cialis .It really works. I take 10 mg within 30 min of sex and I usually have no problems staying rock hard. Usually lasts around 36 hours. I used prescription Lily brand for a couple of years but could not afford the price. Tried getting them online for the past two years and it works great! I love the quality of the products and the fact that the prices are the best online.
Cheers!

 Just wanted to talk a little bit about what is happening and update everyone. I have been taking some supplements, doing ved, also using Absorbine jr., DMSO, topical vitamin E. I started pentox and Cialis a few weeks ago. I have had problems with ED in the past as well. Loss of about a half inch and girth from the dents. However lately I have been walking around with a half hard dick. It's kind of a different and great feeling knowing something is working. I have also boosted my testosterone per my doctor to 100 milligrams weekly. It's great because at 57 I feel 30 again LOL. I have had a greater time being able to get a real good hard on most of the time for sex. The only thing not happening is night and morning hardons. However I do get get semi hard whenever I piss (odd?) I have also had no further acceleration of the Peyronies Disease either. What say all of you?

mischa, I do reverse Kegels when I take a piss, leaves you with somewhat of a 'chubby' for a few minutes at a time, which is nice  :)