News:

New app for Peyronies self assessment - Details here



Recent posts

#91
Have you guys noticed good and bad days in the acute stage ? Some days I have 0 pain, with a low and full flaccid hang and great erectile function, other days I notice slight pain with more penile retraction and less erectile function. Just wondering if this is a normal occurrence for you all.
#92
Let me ask this, should a VED make me erect with blood or just appear fatter and longer. ?  Yes, it can cause a lump of scar that hits a bone or something.. My partner is wide open.
#93
Progression of Peyronies Disease / New scarring 2.5 years after o...
Last post by samanil - December 26, 2025, 11:25:58 PM
I discovered with shock and horror a large new indent near the base on the right side, almost 3 years after initial onset.

I did supplements and traction for about a year after the onset, but stopped due to no apparent effect. My penis still worked and looked ok, if a little bent. I figured I had stabilized and counted myself lucky. Then a fresh scar emerged out of nowhere (on Christmas day no less).

Anyone have new symptoms emerge after years?
#94
Progression of Peyronies Disease / Re: Agressive peyronies, multi...
Last post by samanil - December 26, 2025, 11:18:23 PM
Thanks for that assessment. Meaningful and uplifting.
#95
I too have chronic pelvic pain syndrome and have to do exercises and stretching movements to keep things loose. Otherwise the tightness of my pelvic floor can get pretty bad at times.
#96
Can now pretty easily handle 13cm rod base length, and am now starting the day with this. Now just working those thumbscrews further each day. I actually did end up with a slight ache near the glans, partly makes me happy as it seems the intensity I'm using is correct as I'm able to progress with rods/thumbscrews.

In regards to the tension - I've been keeping it at or past the 3rd line for most of my sessions (650g), and I've been doing 4th line more often as of late (920g).

One other observation - the base of the device needs to be pushed down to be centered with my penis for the proper pull, I usually pull the device in to avoid causing any pain from moving it with the offset. then release it back to full stretch on top of this foam yoga block I have which holds it up, and a narrow pillow I use in my spot on the couch.

But going light today - 3 hours just to keep the tissue conditioned, then hopefully tomorrow can keep hitting those higher stretches.

Booked a doctor appointment to figure out next steps on pelvic floor / hip tightness. I'm pretty certain now that I have FAI or hip impingement on my left hip (plaque/curve/tightness on left side of penis). I did the FADIR test and watched some videos on that stuff and with the tests I get pinching pain that is described as a positive for hip impingement. Obviously this is all very self diagnose territory which is why I may as well go to the doctor to hopefully get a path forward to learn more about what it is. Hoping it's not a labrum tear, but who knows - it does seem like it must have some effect on the tightness at the base of my penis (on the left side only). So we'll see what comes of that. fingers crossed.

merry Christmas as well - all i wanted was to wake up with a Johnson straight as an arrow, but gotta carry on lol
#97
Developmental Drugs & Treatments / Info on new treatmens
Last post by Cernfan - December 26, 2025, 04:11:48 PM

Refined Injectable Treatments
The collagenase injection protocol has been improved over time, with studies showing about 20 degrees of improvement in curvature Cleveland Clinic. A significant advancement is combining collagenase injections with penile traction therapy, which yields a 50% improvement in curvature Cleveland Clinic.
Emerging Therapies in Research
Several promising treatments are currently being studied:

Kiwi extract collagenase: Researchers in Canada are developing a natural collagenase from kiwi extract that may offer a middle-ground therapy between current options Urology Times, though experts note we're realistically 5-10 years away from new treatments being released.

Phosphodiesterase inhibitors: Research published in March 2025 showed that inhibition of phosphodiesterases 1 and 4 prevents myofibroblast transformation UroToday, which could address the underlying disease mechanism.
Topical treatments: Studies are examining H-100 gel, which when applied to the penile shaft has been shown to infiltrate the tunica albuginea UroToday.

Novel Experimental Approaches

Adipose-derived regenerative cells: A 2024 Danish pilot study injected patient-derived regenerative cells into plaques, which proved safe though didn't significantly reduce curvature ScienceDirect. Patients did report subjective improvements and reduced distress.
Fractional CO2 laser: A pilot study showed a median reduction in curvature from 37° to 28° at 52 weeks when combined with topical triamcinolone and penile modeling Cuaj.

Despite these advances, experts acknowledge that we still don't fully understand the disease's pathophysiology and lack a truly reliable nonsurgical treatment Nature. Surgery remains the gold standard for significant curvature correction, while penile traction therapy and Xiaflex injections are the most evidence-based nonsurgical options currently available.Claude is AI and can make mistakes. Please double-check cited sources.
#98
Same to all of you!!
#99

He did however suggest that traction would be ineffective for those who have had their plaque identified on ultrasounds...Not a view I would see supported by manufacturers of traction devices.

On a separate note, I fully agree with his point about Peyronies still being treated as a taboo subject. If more men came forward and spoke openly about it, maybe better treatment options would be developed sooner rather than later. I used to think it was a really rare disease but in reality, it's most likely underreported and far more common than we realise.
#100
Merry christmas guys! Wanted to wish everyone happy holidays and a happy new year!  8)