49 y/o wm here with diagnosed Peyronies Disease. My Peyronies Disease is actually inside and causes my penis to have hourglass shape when erect. The knot is about 2 inches from the base so the other 4 inches only gets semi erect. It's never rigid and intercourse is difficult at times. Due to being in the middle and pulling the surrounding tissue inward is has actually decreased the diameter / girth of my penis from the knot out to the tip and it's a very noticeable difference in size. The Urologist told me that because the plaque is inside and not causing curvature that the insurance co will not authorize the Xiaflex treatment option and suggested surgery to remove the effected area which is a big area. I have been taking supplements in hopes of having some help, but to date nothing is working. Thanks for reading.
I founded this forum and administered it for about 15 years and I have no idea what "it is inside" even means. All Peyronies Disease plaque is inside.
My personal opinion is if I were going to have surgery, I would at least check on implant surgery from a top surgeon. At 50 I think there is too much of a chance that your erections are not going to be satisfactory after excision and you would end up with an implant anyway. Going straight to an implant saves you one surgery and will correct your size loss and erections in one outpatient surgery.
Its probably good that you read over this entire post so you have at least an introductions to the basic issues. https://www.peyroniesforum.net/index.php/topic,3180.0.html
Quote from: Hawk on September 20, 2019, 09:05:56 PM
I founded this forum and administered it for about 15 years and I have no idea what "it is inside" even means. All Peyronies Disease plaque is inside.
My personal opinion is if I were going to have surgery, I would at least check on implant surgery from a top surgeon. At 50 I think there is too much of a chance that your erections are not going to be satisfactory after excision and you would end up with an implant anyway. Going straight to an implant saves you one surgery and will correct your size loss and erections in one outpatient surgery.
Its probably good that you read over this entire post so you have at least an introductions to the basic issues. https://www.peyroniesforum.net/index.php/topic,3180.0.html
What do you mean Hawk? With all peyronies plaque is inside? Do you mean inside the skin on the penis? Or inside the penis itself?
It is scar tissue either in the tunica wall or possibly in the cavernosa. There are no other options
Be sure to read through the survival guide: https://www.peyroniesforum.net/index.php/topic,3180.msg44057.html#msg44057
Even before surgery it's great to start pentox, nightly PDE5i, and traction/VED to minimize size loss until surgery.
By "inside" means that it's not on the top causing a curvature up or side causing curvature sideways. It is in the dead center and pulls all tissue inward around the diameter of the shaft creating the hourglass shape. Because there is no curvature I am not eligible for injections of Xiaflex.
That's similar to what I had.
There's a difference between a plaque sitting "ontop" of the tunica and "inside" towards the septum. The Smooth muscle structures can't expand anymore at the site of the plaque, leading to the hourglass form.
Oral supplements are good but they might not reach the area where your plaque sits. I would apply transdermal solutions(DMSO+x) as often as possible to flood the tissue with anti inflammatory or anti calcium channel solutions(verapamil).
Then some sort of traction or pumping to stretch the tissue(without causing more problems)
No medical research supports transdermal applications that I've seen.
"medical research" isn't needed to make something work ;)
Some things just need logical understanding of how it works.
Transdermal use of DMSO for example is well understood. Knowing how a peyronies plaque is structured. Then knowing what substances are "antonymous" to it.
Then knowing their molucular weight and how to apply such a transdermal agent gives you the power to do what isn't yet researched.
Of course if you're opposed to anything that isn't proven in a medical setting then all my points are moot ;)
Tell me more about DMSO. Not familiar with that or it's uses. I'm open to experimenting with many things because there is no "one size fits all" cure with this disease. I have been reading some research data on an oral drug called Potaba and its effectiveness on some people in controlled studies. Thinking about asking the Urologist to prescribe it for me and see if it will work in combo with the OTC supplements I am taking. At this point it's worth a try if he'll prescribe it.
DMSO , you need to research and understand cause it has some risks and you can find a lot about on this forum putting it into the search. I have new thread about it going RN too. You can ask me detailed questions there.
DMSO is basically enabling supplements of low molecular weight to be shuttled beyond the skin barrier. This would be possible with POTABA and PABA. I think the biggest problem with peyronies is that the penis is a bad spot for an injury and medicine to reach it via the oral-stomach->blood circulation pathway. That's logic led me to focus on the transdermal route applying directly to the site of injury.
As an Introductory, this topic has ended.
Please discus specific subjects on the relevant boards
James