Not sure if this is the right forum, but obv mods can move if it is not.
Scar Tissue Turned Into Heart Muscle Without Using Stem Cells
Apr. 26, 2012 — Scientists at Duke University Medical Center have shown the ability to turn scar tissue that forms after a heart attack into heart muscle cells using a new process that eliminates the need for stem cell transplant.
Scar tissue turned into heart muscle without using stem cells (http://www.sciencedaily.com/releases/2012/04/120426174110.htm)
Sounds promising. It says therapies could be developed within a decade. It seems like all the best remedies on the horizon are so far away. Maybe too late for us old guys, but not for the younger victims of this awful disease. It does bring hope.
skunkworks
Thanks for the link. It sounds promissing as Restore has wrote ;D
Also maybe too late, again as Restore has wrote for some of us, more aged :(
James
Since this sounds like it's not as risky as stem cell therapy (issues such as tumor growth, difficulty controlling process, etc.), I bet the therapies will come sooner than 10 years, especially if this means reversing damage from heart attacks. And, if it works for those type scars, there is hope for us!
Restore
Your assessment sound logic. :)
Heart attack is taken much more seriously than Peyronies. >:(
James
Well, the article turned out to be open access after all. Here is the link:
MicroRNA-Mediated In Vitro and In Vivo Direct Reprogramming of Cardiac Fibroblasts to CardiomyocytesNovelty and Significance (http://circres.ahajournals.org/content/110/11/1465.short)
Thanks for posting the full text nescio
Not at all skunkworks. I have spent a long time organising a library with research on Peyronies Disease, Penile Fibrosis, and Priapism. Should anyone need a particular article, I'll do my best to find it and upload it here.
Nescio,
I asked you in other topics to introduce yourself and tell us a little about your interest in Peyronies Disease. You haven't responded to my posts.
Hawk
Administrator
Hawk,
I have sent you a PM. If you have not received it let me know, because it does not appear in my Sent Items.
Nescio.
Why the secrecy Nescio?
Hawk is indeed the Administrator of this forum but other members may be also interested in your interest on Peyronies and your motives to be on the forum.
James
Quote from: Nescio on April 01, 2013, 04:57:13 AM
Not at all skunkworks. I have spent a long time organising a library with research on Peyronies Disease, Penile Fibrosis, and Priapism. Should anyone need a particular article, I'll do my best to find it and upload it here.
Hey Nescio, I don't have any specific article requests off the top of my head, but anything interesting you have on penile fibrosis would be very interesting to see.
Do you only collect papers specifically focused on the penis or do you collect ones that might be relevant due to being about out of control fibrosis? Drug treatment of capscular contracture for instance, which should have application to Peyronie's.
James,
I plan on putting my story on the forum, but I need the time to put it into words and do it justice. That was essentially what I wrote in my PM to Hawk.
Skunkworks,
Quote from: skunkworks on April 01, 2013, 07:18:31 PM
Hey Nescio, I don't have any specific article requests off the top of my head, but anything interesting you have on penile fibrosis would be very interesting to see.
I had intended to do that. What I meant was, if you come across an article and you want to read it in full, I may be able to upload it here. As for your question, I do have articles that do not address Peyronies Disease as a main theme, but whose results, nonetheless, may be of significance for it. Examples include research on Dupuytren's, Urological Imaging and on dealing with fibrosis in general. Are there any specific articles on Capsular Contracture you'd be interested in reading? I just did a search of my "database" and could not find any. I will look into it once I have the time. Thanks for pointing it out. One last thing, I have found a patent application in the US for a method of "treating fibrosis", as the inventors claim. I have not had a chance to go through it and I have posted it in the forum (Retinoid-Liposomes for Treating Fibrosis - Peyronies Society Forums (https://www.peyroniesforum.net/index.php/topic,3297.0.html)), but it seems it is related to the work in the article in this post. Both use mRNA, and both, in a way, "treat" fibrosis. Obviously, this is pure conjecture on my part.
I am glad to hear that Nescio, we are hear to support you.
Quote from: funnyfarm on April 02, 2013, 08:49:16 AM
I am glad to hear that Nescio, we are hear to support you.
It means a lot to me. Thank you.
Many many posts ago, George99 linked to a few abstracts of case studies that showed complete regression of fibrosis, in conditions other than peyronie's of course. When I have time I will trawl back and find them, as the full text would be great. Your contribution is greatly appreciated on this end Nescio.
Were you able to find any of those older posts?