Peyronies Society Forums

Peyronies Disease TREATMENT Discussion Boards => Xiaflex Injections => Topic started by: male_patient on April 29, 2021, 01:12:04 PM

Title: Should Xiaflex shot be this painful?
Post by: male_patient on April 29, 2021, 01:12:04 PM

I got two shots of (in 2 separate days) Xiaflex and the pain during the shots was unbearable. I was screaming bloody murder. I could never imagine pain like this in my life. Is this normal?   If I have to do the second sets, I'm not sure I'll be able to tolerate it. I can deal with pain, but this is something out of nightmares. 
   
Title: Re: Should Xiaflex shot be this painful?
Post by: LWillisjr on April 29, 2021, 01:41:22 PM
They always gave me 2 injections for pain blocking with a much smaller needle first. Then after 10 minutes or soo came in with  the big needle for the Xiaflex. I assume it is really dependent on your doctor.
Title: Re: Should Xiaflex shot be this painful?
Post by: male_patient on April 29, 2021, 02:08:41 PM

The second time I was there, I asked if they could numb it. The doctor said, Nah, it would be just as painful.   
Title: Re: Should Xiaflex shot be this painful?
Post by: Shane43 on April 29, 2021, 02:34:59 PM
I have had 6 injections. Each was painful for just 5-10 seconds and then it was fine. No numbing shot either. Now the swelling that happened later, especially after my 6th shot, was a bit scary and more painful.
Title: Re: Should Xiaflex shot be this painful?
Post by: male_patient on April 30, 2021, 10:06:38 AM

Per govenment website : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708590/

"... not uncomfortable to receive.."   lies lies lies     >:(


Pain
Although Xiaflex is not uncomfortable to receive, some patients have significant pain for up to 48 hours after the injection, with rare patients having discomfort beyond this period. Verapamil is more painful to receive, likely due to the volume of fluid, but is not significantly painful thereafter.
Title: Re: Should Xiaflex shot be this painful?
Post by: BadLuck on April 30, 2021, 10:37:01 PM
I went through 6 rounds of Verapamil injections and I just had my 5th Xiaflex injection this week.  Each of the Verapamil injections was preceded by a numbing injection.  With Xiaflex, there is no such injection.  I believe the needle gauge is larger for Verapamil than it is for the Xiaflex injections.
Honestly, I though they were all pretty painless.  I would equate it to a wasp sting. 
Title: Re: Should Xiaflex shot be this painful?
Post by: Xavier99 on May 01, 2021, 07:54:32 AM
Badluck did you have any results from verapamil? Is there anywhere you can still get those these days. Nobody around me would shoot me w/ it
Title: Re: Should Xiaflex shot be this painful?
Post by: Hawk on May 01, 2021, 08:21:05 AM
Guys,

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Title: Re: Should Xiaflex shot be this painful?
Post by: Mikel7 on May 01, 2021, 12:58:26 PM
I would have responded to this but I am exhausted from trying to go back and read about the posters history.     :-\
Title: Re: Should Xiaflex shot be this painful?
Post by: chas on May 04, 2021, 02:18:45 AM
I'd  like to add that I received a numbing injection and didn't feel a thing from the Xiaflex.
One of the anaesthetics wasn't 100% effective and the Xiaflex was damn uncomfortable.