I'm not having issues getting an erection and if I did that's why I have generic Viagra. So no need to take Cialis here.

All forms of Peyronies would be a deformity and it seems the traction device by restorex would help all forms even hourglass divots. Because I have a divot it does bend slightly downwards right before where the circumcision scar is and that it does cause shortening by about .25 inches. I'm not sure I want to mess with a traction device yet but I'm thinking it's worth considering trying it to help correct that slight bend. Now would be the time in the acute phase as once it becomes permanent it seems pretty futile to try anything to correct it without more severe interventions such as surgery.

Quote from: pey ron on October 21, 2025, 09:16:51 PManother correction: I contacted peptide sciences and they do not offer custom synthesis. So, only B7-33 can currently be sourced from them.

It won't work. B7-33 focuses on a relaxin receptor RXFP1 that is primarily expressed in lungs and kidneys. E4 endostatin is really the only option if it can be synthesized. I've read a couple threads about it on here and you guys have some interesting ideas about it but they're not correct. First, off the dose is 0.08 mg/kg. That is the minimum effective dose. Human equivalent dose is by converting 20ug/20g mouse dose to reference 60kg for humans. So 4.8mg for 60kg human. Adjust to actual dose using own weight. Secondly, you should be able to inject subcutaneous into fat near the problem site, but it's a systemic peptide and will likely migrate through body. I say should because their research indicates that it's one potential route of administration. Lastly, E4 is the only known peptide that claims reversal of fibrosis. B7-33 might be able to do that, but I think it's more likely a preventative anti fibrotic than effective as a reversing one. Lastly, E4 has a successor called END55/E3-Fc (C67A)/iBio-CFB03. I think their justification on ROI is that they made stuff too complicated. END55 was about attaching a secretory leader peptide and a 232 chain fusion protein to the thing. The idea was to make END55 the final end product and tacking on the two groups was to increase blood serum concentrations for longer. That probably caused their production costs to explode and frankly I think they would have been better off sticking with running the E4 trials and using that revenue to justify an improved version.

PS: Looking at your stack, you might also discuss daily low dose Cialis. On the forum there is a lot of anecdotal feedback that daily Cialis helped to stabilize the disease. For me it even improved my deformity and reduced pain. As you are early in the disease it's anti fibrotic properties could help reduce the progression. Definitely something I would discuss with my urologist if I was in your stage if the disease.

Hi. I don't use Pentox, but the multiple supplements + Cialis I take dropped my blood pressure. I think that is a similar side effect with Pentox (and why I avoid taking it in addition to my stack). My doctor recommended me to drink lots of water and drink bone broth regularly for electrolytes. 

Also I started regular exercise (weekly weight lifting and 20 min daily HIIT) and Sauna and this stabilized my blood pressure. I was around 85/50 morning blood pressure. Now I am stable around 105/60 morning blood pressure which made my lightheaded feeling go away.

Maybe you could discuss these interventions with the doctor to see if they are safe for you to try.

Adding in Cialis or tadalafil will help with reducing inflammation and also assisting with erections. Traction is implemented in the event that you have shortening or a deformity. Read up on our survival guide regarding such.

You will never know for sure if this was the cause or not. I am glad that your hormone function did come back. For some men it does not. Finasteride can be a very dangerous drug for some men.

Quote from: 80degreesUp on December 04, 2025, 10:58:20 PMI'm a 68 YO MALE,

Hello, I guess my curiosity is why you are focusing so much on the G-spot and being able to reach it when it isn't necessary to satisfy your wife.

I have a very healthy and satisfying sex life with my husband and we rarely have actual intercourse.we satisfy each other orally and with our hands or occasionally toys but again not focusing on finding the G-spot

Is the act of intercourse more important to her or to you?

Stabler

I had an operation 9 yrs ago - it was congenital. Best decision I've ever made. https://www.peyroniesforum.net/index.php/topic,7734.0.html

Yes, I have considered the AMS. Met with 2 high volume surgeons and they were pushing the Titan but think more because they are Coloplast COEs. I do have 70 degree curvature so want that corrected with the best implant. I am meeting with a high volume AMS surgeon in January then will make a decision.

Anyone else need to quit caffeine while on pentox? Did it help with lightheadedness?

Any other methods to minimize lightheadedness?