Peyronies Society Forums

Special Boards => Resource Library => Topic started by: Hawk on December 29, 2007, 09:11:24 AM

Title: Clinical Studies Relating to Treatment of ED
Post by: Hawk on December 29, 2007, 09:11:24 AM
Under this resource topic, we will link to clinical studies or place excerpts of those studies that relate to the treatment of ED.
Title: L-Arginine and Pycnogenol for the treatment of ED
Post by: Hawk on December 29, 2007, 09:12:13 AM
A study indicating that that the supplements of L-Arginine and Pycnogenol help with erectile dysfunction

http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&list_uids=12851125&cmd=Retrieve&indexed=google
Title: Acetyl-l-carnitine (ALC)/Propionyl-l-carnitine (PLC) increase efficacy of Viagra
Post by: Hawk on December 29, 2007, 09:15:13 AM
Hawk, here's a study I found that claims ALC and PLC taken together increase the efficacy of viagra in prostate surgery patients. 
Nemo

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VJW-4HHNH61-17&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=489386e31a2c990da6843bd84d1d44c2

Note that PLC is also beneficial for those with diabetes related ED:

Quote from: PubMedCONCLUSION: PLC plus sildenafil was more effective in reducing SI and endothelial dysfunction markers in patients with type 2 diabetes and ED.

http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=17478034&dopt=AbstractPlus (http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=17478034&dopt=AbstractPlus)

Quote from: PubMedCONCLUSIONS: Salvage therapy with PLC plus sildenafil was more effective than sildenafil in the treatment of ED in patients with diabetes refractory to sildenafil monotherapy.

http://www.ncbi.nlm.nih.gov/pubmed/15383186?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus (http://www.ncbi.nlm.nih.gov/pubmed/15383186?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus)


Quote from: Life Extension Magazine (a commercial supplement site)The combination of 2 grams each of PLC and acetyl-L-carnitine daily was more effective than testosterone at improving nocturnal penile tumescence and the International Index of Erectile Function score, an important measure of erectile and sexual function. PLC and acetyl-L-carnitine thus appear to be safe, effective agents for managing male sexual dysfunction.42

http://lefcms.lef.org/magazine/mag2005/dec2005_supp_atherosclerosis_02.htm (http://lefcms.lef.org/magazine/mag2005/dec2005_supp_atherosclerosis_02.htm)
Title: Re: Clinical Studies Relating to Treatment of ED
Post by: Tim468 on December 30, 2007, 10:49:44 AM
I had a very modest, but measurable, improvement in my own "ED" (in quotes because I have not had complete ED, but "flagging erection quality" - softer than it used to be), using these supplements.

I did not see any change in my Peyronies. The other issue I have with these studies is that they seem to come from only Italy, and have not been verified in a multi-center, double blinded, placebo controlled study. Given the lack of efficacy that others are finding with Verapamil iontophoresis, for example, it makes one wonder about the veracity of Italian data in general.

Tim