Based on his videos, it sounds like @NeoV had a similar condition.

I have peyronies and have had it for 15 years. Having sex is hard but I can do it the problem. I am having now is that I cannot keep it hard. I've had an ultrasound done and they say that there is a lack of blood flow to my penis. I was wondering if anybody had any advice or use the tens unit on my legs and feet for neuropathy blood flow working in my legs and feet I was wondering if anybody had any recommendations what do they think that if I were to use the tens unit on my penis with a low setting that will help get the blood flow started again. I don't know what the problem definitely is lack of blood to my penis or weather The position I need to get in to have sex tires me out to where I can't finish because I am a 70 year old man.

Quote from: Mikel7 on Today at 05:52:19 AMSo have you been diagnosed with peyronies or just have a congenital curvature? The way you describe this is just the opposite of a typical plaque formation and a curvature forming. I would say at least try some traction and stay with it too see if you have any improvements. Remember that with the PMP you must invest time. I started with that device and I usually logged in about 6 to 8 hours a day. I split the time up into mornings and evenings.

I had upward congenital curvature but it worsened after I woke up with a penile fracture (purple swollen penis etc.) and I now feel plaque and indentation on the bottom of my penis. I am 100% sure it's Peyronies.

So have you been diagnosed with peyronies or just have a congenital curvature? The way you describe this is just the opposite of a typical plaque formation and a curvature forming. I would say at least try some traction and stay with it too see if you have any improvements. Remember that with the PMP you must invest time. I started with that device and I usually logged in about 6 to 8 hours a day. I split the time up into mornings and evenings.

It is difficult to address exactly which way to go. You definitely have had a couple surgeries which I'm sure has been expensive $$. On looking back over your experience can you judge the quality of improvement from any of them? I would be hesitant to undergo the knife again. Xiaflex injections will dissolve any scar tissues and plaques. I am not educated on the use of it for congenital curvatures. Remodeling after Xiaflex is what will promote straightening and healing of the penis. Is this what Dr Trost has recommended and discussed with you? I would at least give VED a try as it is noninvasive.

Welcome ctst21 to the forum. As Stabler has stated please fill in your signature line and please download and study our survival guide.

It is impossible to say whether this is the start of peyronies or not. So is the beta blocker for high blood pressure? I would definitely get in to see a urologist, hopefully one who is a peyronies specialist if possible. I would educate yourself first on peyronies and then make up a list of questions for the Dr. There opinion on traction and VED therapy. Also how many peyronies patients have they treated?  You should get an idea if they are knowledgeable with treating peyronies patients or not. Sometimes you will find a Dr who is willing to work with you.

If possible you should get an erect ultrasound which will give a clearer picture of what is going on. For the pain you could look into applying some heat therapy for some healing and relief, it does work for a lot of men. Diagnosing pain in the penis is difficult as it could be related to so many other things. Pelvic issues, prostate issues and rough sex can all cause some form of pain either direct or refereed.

Worrying about it will only make things worse. You don't have a deformity and your erections are good. Strong erections will stretch things out and bring in fresh oxygenated blood but shouldn't cause peyronies. Study the forum and again welcome!

Mikel7

I have a significant dent on the ventral side of the base of my penis, and a ~90 degree upward curve (curving straight up from the site of the plaque.) I'm 100% sure that what I have is Peyronies. The problem is that everyone I ask insists that this is possible and that upward curvature can only occur in the case of dorsal plaques. Does anyone else have experience with this? Surely I'm not the only one. I'm having quite a bit of trouble with determining how I should use traction for a case like this.

Hi guys,

I still have my New curvature on the left and a hard painful area on the left side as if my penis was not filling with blood on the left side, this has appeared since my last surgery with Dr Gelman. At the base I had a curvature only downward.

The urologists don't know where my problem comes from, either an old suture that broke, or a problem with the corpus cavernosum after surgery.

All the urologists I've seen, including Dr Gelman, tell me that the only solution is another surgery.

All except Dr Trost, who says that the best solution would be Xiaflex injections, bearing in mind that I don't have Peyronie's, and according to the Doppler I recently had done, there's no fibrosis except for slight scars around the old sutures.

I was also able to chat by e-mail with Dr Djinovic in Serbia who also recommends surgery, but he didn't inspire confidence in me, it seems too easy for him and he's not very explanatory, plus the price for my surgery is much higher than other guys I've talked to.

So I'm very confused by the lack of consensus between doctors. What do you think? Has anyone had Xiaflex for congenital curvature with Dr. Trost?

Currently, I'm going to try VED soon, as recommended by a local urologist.

April

Spirito L, Manfredi C, La Rocca R, Napolitano L, Preto M, Di Girolamo A, Arcaniolo D, De Sio M, Creta M, Longo N. Long-term outcomes of extracorporeal shock wave therapy for acute Peyronie's disease: a 10-year retrospective analysis. Int J Impot Res. 2024 Apr;36(2):135-139. doi: 10.1038/s41443-023-00673-w. Epub 2023 Feb 14. PMID: 36788352.

Maremanda AP, Du Comb W, Able C, Kohn TP, Unal S, Burnett AL. Erectile dysfunction and Peyronie's disease diagnosis rates after penile fracture-a retrospective claims database cohort analysis. Int J Impot Res. 2024 Apr;36(2):125-128. doi: 10.1038/s41443-023-00746-w. Epub 2023 Aug 4. PMID: 37542153.

Zugail AS, Alshuaibi M, Lombion S, Beley S. Safety and feasibility of percutaneous needle tunneling with platelet-rich plasma injections for Peyronie's disease in the outpatient setting: a pilot study. Int J Impot Res. 2024 Apr;36(2):140-145. doi: 10.1038/s41443-023-00744-y. Epub 2023 Aug 7. PMID: 37550385.

Loloi J, Schuppe K, Reddy RV, Rahman F, Bernstein A, Reddy P, Kulkarni N, Masterson T, Ramasamy R. A survey of exposure to the use of Xiaflex for the treatment of Peyronie's disease among United States urology residency programs. Int J Impot Res. 2024 Apr;36(2):155-159. doi: 10.1038/s41443-023-00781-7. Epub 2023 Oct 21. PMID: 37865716.

Kadıoğlu A, Gürcan M, Rakhmonovich AF, Dursun M. Surgical management of complex curvature in Peyronie's disease. World J Urol. 2024 Apr 30;42(1):276. doi: 10.1007/s00345-024-04936-z. PMID: 38689034; PMCID: PMC11061042.

Schneider D, O'Leary M, Amini E, Miller J, Hassas N, Nguyen J, Hammad MAM, Barham D, Yafi FA. Peyronie's disease response to intralesional collagenase clostridium histolyticum therapy is independent of baseline testosterone. Andrology. 2024 May;12(4):830-834. doi: 10.1111/andr.13532. Epub 2023 Sep 27. PMID: 37753943.

February

Larson H, Warner J, Savage J, Kohler T, Ziegelmann M, Trost L. Changes in Point of Maximal Curvature During Collagenase Clostridium Histolyticum Injections for Peyronie's Disease. Urology. 2024 Feb;184:122-127. doi: 10.1016/j.urology.2023.11.024. Epub 2023 Dec 6. PMID: 38061610.


Cilio S, Rocca R, Celentano G, Marino C, Creta M, Califano G, Manfredi C, Russo GI, Morgado A, Falcone M, Capece M; YAU Working Group Sexual and Reproductive Health. Intraplaque injections of hyaluronic acid for the treatment of stable-phase Peyronie's disease: a retrospective single-center experience. Asian J Androl. 2024 Feb 2. doi: 10.4103/aja202371. Epub ahead of print. PMID: 38305689.


Wang X, Bao X, Liu H, Cui Y. Exploring the pharmacological mechanism of Herba Epimedii (yinyanghuo) for Peyronie's disease with network pharmacology strategy. Asian J Surg. 2024 Feb 20:S1015-9584(24)00270-7. doi: 10.1016/j.asjsur.2024.02.012. Epub ahead of print. PMID: 38383197.

Garaffa G, Traunero F, Claps F, Pavan N, Rossin G, Piasentin A, Rizzo M, Biasatti A, Zorzi F, Trombetta C, Liguori G, Ongaro L. Plication surgery does not produce additional loss of length in Peyronie's disease patients. Int J Impot Res. 2024 Feb 22. doi: 10.1038/s41443-024-00852-3. Epub ahead of print. PMID: 38388784.

Levine LA, Desouky E, Elist JJ, Moon D, Wilson SK. Use of Himplant® for correction of residual deformity following prior treatment of peyronie's disease: a case series. Int J Impot Res. 2024 Feb 23. doi: 10.1038/s41443-024-00840-7. Epub ahead of print. PMID: 38388785.

Ledesma BR, Velasquez DA, Egemba C, Molina M, Ibrahim E, Costantini-Mesquita F, Deebel NA, Han S, Reis IM, Saltzman R, Ramasamy R. A phase 2 randomized, placebo-controlled crossover trial to evaluate safety and efficacy of platelet-rich plasma injections for Peyronie's disease: clinical trial update. Int J Impot Res. 2024 Feb 29. doi: 10.1038/s41443-024-00844-3. Epub ahead of print. PMID: 38424354.


March

Thach S, Pommier B, Soulier V. The impact of Peyronie's disease on couples. Fr J Urol. 2024 Mar 4;34(4):102595. doi: 10.1016/j.fjurol.2024.102595. Epub ahead of print. PMID: 38442548.

Rassweiler JJ, Scheitlin W, Goezen AS, Radecke F. Long-term experiences with high-energy shock wave therapy in the management chronic phase Peyronie's disease using two different electromagnetic lithotripters. World J Urol. 2024 Mar 7;42(1):124. doi: 10.1007/s00345-024-04792-x. PMID: 38453751; PMCID: PMC10920406.

Şahin A, Babayev H, Cirigliano L, Preto M, Falcone M, Altıntas E, Gül M. Unveiling the molecular Hallmarks of Peyronie's disease: a comprehensive narrative review. Int J Impot Res. 2024 Mar 7. doi: 10.1038/s41443-024-00845-2. Epub ahead of print. PMID: 38454161.

Institute for Quality and Efficiency in Health Care (IQWiG). Penile traction therapy for induratio penis plastica: IQWiG Reports – Commission No. N22-01 [Internet]. Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2024 Mar 8. PMID: 38574187.

Hatzichristodoulou G, Gültekin MH, Özkara H, Akkus E. First worldwide correction of ventral Peyronie's disease utilizing rigicon inflatable penile prosthesis combined with plaque incision & grafting with collagen fleece (PICS-technique) for residual curvature. Int J Impot Res. 2024 Mar 13. doi: 10.1038/s41443-024-00873-y. Epub ahead of print. PMID: 38480871.

Jin DC, Luo Y, Wang P, Zhang Y, Bi G, Tong DL, Wang YY, Zhou WY, Li YF. Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease. J Vis Exp. 2024 Mar 15;(205). doi: 10.3791/66305. PMID: 38557978.

Paulis G, De Giorgio G, Paulis A. Ultrasound Elastography as a Diagnostic Tool for Peyronie's Disease: A State-of-the-Art Review. Diagnostics (Basel). 2024 Mar 21;14(6):665. doi: 10.3390/diagnostics14060665. PMID: 38535085; PMCID: PMC10969672.

Giagulli VA, Lisco G, De Tullio A, Guastamacchia E, Triggiani V, Jirillo E. The pathogenic role of the immune system in erectile dysfunction and Peyronie's disease: focusing on immunopathophysiology and potential therapeutic strategies. Sex Med Rev. 2024 Mar 26;12(2):210-220. doi: 10.1093/sxmrev/qead055. PMID: 38196188.

"This study is to our knowledge the first analysis of temporal gene expression associated with the regulation of the transformation of resident fibroblasts to profibrotic myofibroblasts in Peyronies Disease. Further research is warranted to investigate the role of the MAPK-Hedgehog signaling pathways in reversibility of Peyronies Disease.'

Spirito L, Manfredi C, La Rocca R, Napolitano L, Di Girolamo A, Capece M, Trama F, Sciorio C, Sokolakis I, Creta M, Arcaniolo D. Daily low-dose tadalafil may reduce the penile curvature progression rate in patients with acute Peyronie's disease: a retrospective comparative analysis. Int J Impot Res. 2024 Apr;36(2):129-134. doi: 10.1038/s41443-022-00651-8. Epub 2022 Dec 13. PMID: 36513814.