Peyronies Society Forums

Erectile Dysfunction Forum - for all men with ED => Oral Drugs and Supplements for Erectile Dysfunction => Topic started by: stupendousman on September 18, 2022, 11:05:35 AM

Title: Pentoxifylline permanently help?
Post by: stupendousman on September 18, 2022, 11:05:35 AM
Hi, I have been prescribed pentoxifylline 400mg to take 3 times daily. It seems to be helping me. However, I don't like the side effects (drowsiness upset stomach etc.)

If I stop taking the pentoxifylline will the scar tissue return to "pre pentoxifylline" state or will it stay in the same state it is when I stop? I guess my question is does pentoxifylline permanently break up the scar tissue or only while on treatment?
Title: Re: Pentoxifylline permanently help?
Post by: pauli on September 18, 2022, 12:26:58 PM
I have not heard of one person that had improvements in curve or length or indentation or plaque with any oral treatment. Maybe increased blood flow, but nothing else. And maybe increased blood flow protects you from further damage through trauma but that's it. Don't put to much hope in any treatment. If anything would really help, this forum would not exist....

Title: Re: Pentoxifylline permanently help?
Post by: Pfract on September 18, 2022, 01:06:13 PM
stupendousman:

Hey there. Unfortunately, the latest evidence points out to pentox not being effective at all. It doesn't harm you, but there is no evidence it actually helps with Peyronies. Other than improving erections due to more blood flow. But you can take it.

It did nothing for me, when i took it


https://malefertilityandpeyroniesclinic.com/peyronies/treatments/
Title: Re: Pentoxifylline permanently help?
Post by: BigJoe11 on September 19, 2022, 08:42:56 PM
I understand everyones comments on ineffective pentox, but the increased blood flow would be welcome. Does anyone know where I can purchase online? Please DM if not openly discussed.
Title: Re: Pentoxifylline permanently help?
Post by: MikecarrNY on October 07, 2022, 06:35:36 PM
Is that sort of the consensus in this board now — skip pentox?

I listened to YouTube training videos (lectures for folks taking their urology boards) from Dr Kashanian at Cornell Weill. 2022 video. He does not prescribe it. Just Cialis.

Same for Dr Trost based on what I read on his board here. Cialis for "internal traction." No Pentox. He did a video on same.

I saw another grand rounds training video from 2022. Same.

I have a prescription for it. I am not taking it yet. I am early stage acute. No curve. Pain. And wondering if I should. The fear of course is it has bad side effects or even somehow mitigates the Cialis I am taking, for no gain.  Just curious what folks think or hear from their docs.
Title: Re: Pentoxifylline permanently help?
Post by: LWillisjr on October 07, 2022, 06:45:17 PM
It doesn't mitigate the Cialis, they both improve blood flow. And being in acute phase improving blood flow makes sense.

If it were me, I would try the pentox. If you experience side effects, then just stop taking it.

Title: Re: Pentoxifylline permanently help?
Post by: bentoboy on October 08, 2022, 09:00:50 AM
Quote from: MikecarrNY on October 07, 2022, 06:35:36 PM
Is that sort of the consensus in this board now — skip pentox?

I listened to YouTube training videos (lectures for folks taking their urology boards) from Dr Kashanian at Cornell Weill. 2022 video. He does not prescribe it. Just Cialis.

Same for Dr Trost based on what I read on his board here. Cialis for "internal traction." No Pentox. He did a video on same.

I saw another grand rounds training video from 2022. Same.

I have a prescription for it. I am not taking it yet. I am early stage acute. No curve. Pain. And wondering if I should. The fear of course is it has bad side effects or even somehow mitigates the Cialis I am taking, for no gain.  Just curious what folks think or hear from their docs.

what does he mean by 'internal traction'?
Title: Re: Pentoxifylline permanently help?
Post by: nemo on October 08, 2022, 10:17:46 AM
I think he just means that having a good erection is stretching the scar tissue "from within" just as traction would stretch it by external means.

nemo
Title: Re: Pentoxifylline permanently help?
Post by: jj21 on October 09, 2022, 07:06:30 AM
I found the combination of trental (pentox) and cialis daily (5mg a day) beneficial during the acute stage. Helped a lot with blood flow, and improved erections.

There is a post somewhere on the board which has a collection of user reviews on pentox, some found benefit, some didn't.

I agree with LWillisjr. I would try it if I were you, improved bloodflow can help in the acute phase. If the side effects become too much, I'd stop.

My urologist said, if pentox doesn't do much after 8-9 months, it probably will not be of benefit taking it any longer.  So, you could try it for 8 months at least.