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Peyronies Disease TREATMENT Discussion Boards => Developmental Drugs & Treatments => Topic started by: George999 on November 09, 2009, 07:22:06 PM

Title: Stem Cells & Adult stem cell injections for Peyronie's
Post by: George999 on November 09, 2009, 07:22:06 PM
I am starting this thread to differentiate new novel approaches not quite yet fully in the pipeline from treatments already in the process of being FDA approved.  This is the place for things just a bit more tangible than sci-fi.  And I think there is an increasing amount of this kind of hope out there for the real silver bullet, something that completely restores the penis, not only functionally, but esthetically as well.  - George

Quote from: Health Day

Scientists Grow New Penile Tissue in the Lab (http://www.healthday.com/Article.asp?AID=632879)

In the study, the researchers extracted smooth muscle cells and endothelial cells from the animals' penises. The cells were then separated and grown in the laboratory on rod-shaped collagen scaffolds for support. The scaffold was placed in an incubator and nourished by fluids to mimic conditions inside the body, Atala said.

After the cells had matured, the scaffolding and the newly formed penile spongy tissue, called corpora cavernosa, was surgically implanted into the rabbits' penises.

About a month later, the tissue began to reconstitute itself, forming new blood vessel structures necessary for proper functioning, while nerves from the existing penile tissue integrated into the new tissue. In time, Atala said, the collagen structure was reabsorbed, and the cells built their own collagen structure.

In the treated rabbits, tests showed that pressure inside the penis, a key component of an erection, was normal. Other tests showed that blood flow, response to nitric oxide, drainage of the blood after the erection and presence of sperm in the female vagina were also normal. The tissue engineering worked so well that four of 12 females were impregnated by the repaired rabbits, according to the study.

Title: Re: Treatments on the Horizon ...
Post by: Skjaldborg on November 09, 2009, 08:26:52 PM
Wow. This is much more than theoretical since proof of concept is already happening in animal testing. Amazing! I think in the future, stem cells and tissue replacement will be the cures for Peyronie's. Maybe I should be glad I got this at 30, as in I might see a cure in 20 years...and be young enough to enjoy it! Great find George999.

Skjald
Title: Re: Treatments on the Horizon ...
Post by: newguy on November 09, 2009, 09:54:24 PM
Fantastic. I know the fact that it's on the horion is frustarting, but it's a heartening glimpse into what te future holds.
Title: Re: Treatments on the Horizon ...
Post by: newguy on November 10, 2009, 01:46:48 AM
Now on the BBC News site:

QuoteTissue created in a laboratory has been used to completely replace the erectile tissue of the penis in animals.

The advance raises hopes of being able to restore full function to human penises that have been damaged by injury or disease.

Rabbits given the engineered tissue by the scientists from Wake Forest University in North Carolina had normal sexual function and produced offspring.

The study appears online in Proceedings of the National Academy of Sciences.

Professor Anthony Atala said: "Further studies are required, of course, but our results are encouraging and suggest that the technology has considerable potential for patients who need penile reconstruction.

"Our hope is that patients with congenital abnormalities, penile cancer, traumatic injury and some cases of erectile dysfunction will benefit from this technology in the future."

Reconstructing damaged or diseased penile erectile tissue is a tough challenge because of the tissue's complex structure and function.

The Wake Forest team has already achieved considerable success in the field of tissue engineering, developing whole human bladders that have been implanted into patients.

In a previous study, the researchers engineered short segments of rabbit erectile tissue with 50% of full function.

In the latest work, they harvested smooth muscle cells and endothelial cells from the animals' erectile tissue.

These cells were multiplied in the laboratory and used to seed a three dimensional scaffold, which was implanted into the animals' penis.

Organised erectile tissue with blood vessel structures began to form as early as a month later.

The researchers believe the key was the fact that the cells were injected into the scaffolds on two separate days, enabling them to hold almost six times as many smooth muscle cells as in previous studies.

During an erection, it is the relaxation of smooth muscle tissue that allows an influx of blood into the penis.

The relaxation is triggered by the release of nitric oxide from endothelial cells.

Tests showed that vessel pressure within the engineered tissue was normal and that blood flowed smoothly through it and drained away from it normally after an erection.

When the animals with the engineered tissue mated with females, vaginal swabs contained sperm in eight out of 12 cases. Four of the 12 females were impregnated.

Tim Terry, honorary secretary of the British Association of Urological Surgeons, described the study as "fascinating".

He said complex, highly invasive surgery was often the only option for patients with damaged erectile tissue and the latest work offered long-term hope of a better alternative.

However, he said, much work would be required before the technique could be tested on humans, with potential problems including finding a suitable place to embed the new tissue and ensuring it had an appropriate nerve supply.

"Nevertheless, tissue engineering techniques may well lead to clinical advances with time," he said.
- http://news.bbc.co.uk/1/hi/health/8347008.stm
Title: Re: Treatments on the Horizon ...
Post by: nemo on November 10, 2009, 08:03:43 PM
Scientists growing new penile tissue ... kind of interesting:

http://news.bbc.co.uk/2/hi/health/8347008.stm

Title: Re: Treatments on the Horizon ...
Post by: Iceman on November 10, 2009, 08:58:32 PM
kind of interesting BUT way way into the future - we will all be dead by the time this comes around.
Title: Re: Treatments on the Horizon ...
Post by: Skjaldborg on November 10, 2009, 10:25:21 PM
Iceman,

I would guess that these tissue replacement therapies are about 10-15 years away. Technology is growing by leaps and bounds and what may have taken 20 years in the past to develop may take only 10 now. Take a look at LASIK eye surgery. It was developed in about 10 years based on a discovery in 1980 that a certain kind of laser could etch human tissue and not harm the surrounding area. The device was patented in 1989. By the late 90's, LASIK had become a routine procedure and has since been improved upon. Think about it: shooting laser beams at an eyeball to restore vision became a reality from nothing to actual treatment in about 20 years. In this case, we already have successful animal results for penile tissue replacement and if there is any application to enlarge the penis with this technique in addition to replacing defective tissue, pharmaceutical companies will club baby seals to get there hands on it.

I'm not pinning all my hopes on this by any means, but let me tell you, I have more faith in the progress of these animal studies than I do in a lot of the goofy treatments I see on this forum. People have been using the same things for Peyronie's with limited benefit or no benefit for years and years and years. Why not have a little hope that in a few years we'll have more options than vitamin E, l-arginine, pentox and penile implants?

Also, there are a number of youngsters on this forum, myself being 30. We have the curse of getting this young but we may see better treatments in our lifetimes. If not, I will get an implant when I'm 60 and have sex like I was 20 again.

-Skjald

Title: Re: Treatments on the Horizon ...
Post by: MidLife on November 10, 2009, 10:43:56 PM
It sure is great to hear a little good news about Peyronies Disease.  I am convinced their will be a cure or at least a reliable treatment in next 5 to 10 years.  Lord knows if there was a reliable treatment we would all be willing to pay for it.  Keep the faith Men!

Title: Re: Treatments on the Horizon ...
Post by: jackisback on November 25, 2009, 02:17:12 AM
Before I got the chord on the side of my penis, I was introduced to internet health forums where I obsessed about my premature hair-loss. An often talked about procedure was/is "hair cloning", or more scientifically, "hair multiplication". It was always speculated to be "5-10 years away", but 5-6 years later, nothing seems to have changed there.

This new penis study is encouraging news, sure, but it's much more complex than Lasik (probably...I'm no scientist), and with the current state of the economy and health care reform in America, I would speculate that development for new therapies in general will not accelerate, at least until we work the kinks out. Maybe this will come out someday and your sons will never have to worry about Peyronie's, but I wouldn't count on getting anything substantial from this for another 20 years. If advancements come earlier than that, consider yourself very lucky.
Title: Re: Treatments on the Horizon ...
Post by: jackp on November 25, 2009, 10:38:50 AM
JB

I Agree. We have to look at what we have here and now. In my case with the peyronies and severe ED my last option was an implant.

I am 67 now, why would I wait 10, 20 or more years for something that may happen. Why would I put my sex life on hold for something that may happen?

For me, my implant has been a huge success!!! :)  I took advantage of the what was available now. Have no regrets.

When life hands you a lemon make lemonaide out of it.

Jackp
Title: Re: Treatments on the Horizon ...
Post by: George999 on November 25, 2009, 12:17:35 PM
Quote from: jackp on November 25, 2009, 10:38:50 AM

I took advantage of the what was available now. Have no regrets.

When life hands you a lemon make lemonaide out of it.

Jackp


Actually, I'm not sure the two strategies are mutually exclusive.  I think even for younger guys here with severe Peyronie's problems, the option of surgery does NOT preclude the potential for a far better fix later on as the science progresses.  I certainly recognize the grief that it is to have Peyronie's at a young age, but we have to look at both sides of the equation.  And the other side of that coin is that, for those in their late teens and early twenties, there is much hope for the future.  - George
Title: Re: New Immune System Research Points To New Treatment Approaches ...
Post by: George999 on November 25, 2009, 12:25:03 PM
Australian researchers are probing into the minute details of immune function.  This is opening the door to new and advanced treatment approaches.  They have found for example, that by totally suppressing antigen producing B cells for a limited length of time allows the immune system's regulatory function to 'catch up' and, in effect, stops the auto-immune reaction process.  Although fascinated by the limited information in the abstract, I can not find a way to access the full study, but I am sure it would be equally fascinating.  - George

What B cells can tell us about certain cancers and autoimmune diseases (http://www.garvan.org.au/news-events/news/what-b-cells-can-tell-us-about-certain-cancers-and-autoimmune-diseases.html)
Title: Re: Treatments on the Horizon ...
Post by: jackp on November 25, 2009, 05:02:26 PM
George

I agree surgery is the last option. That said, if I was 25 with peyronies and severe ED why would I wait until 45 or 50 for something that may happen?

If the breakthrough happens it is not difficult for a surgeon to remove the implant. It only goes into the CC but does not replace it.

Jackp
Title: Re: Treatments on the Horizon ...
Post by: George999 on November 25, 2009, 11:51:47 PM
Quote from: jackp on November 25, 2009, 05:02:26 PM
George

I agree surgery is the last option. That said, if I was 25 with peyronies and severe ED why would I wait until 45 or 50 for something that may happen?

If the breakthrough happens it is not difficult for a surgeon to remove the implant. It only goes into the CC but does not replace it.

Jackp

Exactly what I meant by the suggestion that they are not "mutually exclusive".   Have the surgery now if you need it.  And when they perfect regrowing penises sometime in the not so far away future, get the whole thing fixed.  I think the biggest factor is whether things are intolerable, and that is a judgement each guy has to make for himself.  If its just intolerable and you want to kill yourself to relieve the pain, by all means, go for the surgery.  If its already intolerable, surgery is very UNLIKELY to make it worse and is much more likely to make it far better, although not exactly as it was before Peyronie's.  Why suffer?  If its intolerable, GET IT FIXED!  - George
Title: Re: Treatments on the Horizon ...
Post by: Skjaldborg on November 26, 2009, 12:28:55 AM
I agree George999,

Everyone's situation is different and surgery now doesn't necessarily rule out new and better procedures later on. Fortunately, I still have good functioning and the pain is manageable and decreasing with continued use of pentox. The deformity sucks and I sure wish I didn't have it but I don't need surgery right now (even Dr. Lue said so). If it gets worse (which it may) I may consider surgery. If I get an implant and then 10 years later they figure out how to regrow a penis in a test tube, I'll get one of those. I wonder if that's covered by insurance though...

-Skjald
Title: Re: Skjald
Post by: ComeBacKid on November 26, 2009, 04:31:36 AM
You don't even want to get into "whats covered by insurance" I discussed this with a doctor who has peyronies disease himself.  They could make you try every other single treatment before they pay for an expensive injection series, or make you go through appeals.  Not to mention, unless I'm wrong, peyronies is a pre existing condition, that could not be covered due to a "technicality."  If you didn't admit to having it when you got insurance if they asked, you commited insurance fraud and can be charged with a felony crime. 

I wouldn't worry about that at this point, first we have to worry if the drug will work, worst case scenario is it works and your insurance won't cover it, you'll have to make a credit card charge, I guess it could be worse if its just a few thousand dollars, its still worth it.

Comebackid
Title: Re: Yet another emerging therapy with potential to treat Peyronie's ...
Post by: George999 on December 21, 2009, 03:05:24 PM
Quote from: HealthDay

Diabetes Insight Could Lead to Better Treatments

Inhibiting a key inflammatory pathway brought powerful results in mice and people, researchers say
(http://www.healthday.com/Article.asp?AID=634285)

The authors of this study, published online Dec. 21 in Nature Immunology, started their exploration with the NLRP3 inflammasome, which has been linked with different inflammatory diseases.  ...  Inflammasomes are clusters of proteins that stimulate inflammation and play a role in the body's innate immune response, explained Dr. Norma Kenyon, professor at the Diabetes Research Institute of the University of Miami Miller School of Medicine.  ...  "Our findings predict that type 2 diabetes can be treated by inhibitors of the inflammasome or IL-1b," Tschopp said.  ...  Studies in humans are already under way. According to Tschopp, "clinical studies with type 2 diabetes patients have already been initiated and the first results are again incredibly encouraging. With a single injection of IL-1b inhibitors, glucose levels in diabetes patients are highly reduced during six months. This treatment could replace the standard treatment currently used."'



This is about more than just diabetes.  This is about a new approach to treating inflammatory autoimmune processes in general.   - George
Title: Re: Treatments on the Horizon ...
Post by: skunkworks on December 21, 2009, 09:21:41 PM
That article seems to suggest the possibility that glucose control problems are a symptom of inflammation, rather than inflammation being a symptom of glucose control problems. If I read it correctly that is, I only had time to skim it.

Interesting to say the least, although I'd be more leaning toward some kind of feedback going on, glucose problems causing inflammation which exacerbates glucose problems which exacerbates inflammation and so on.
Title: Re: Treatments on the Horizon ...
Post by: George999 on December 21, 2009, 10:24:44 PM
Absolutely, all of these diseases are full of feedback loops.  It is likened to throwing a switch.  Once the switch is thrown it is all but impossible to reset it.  Thats what makes these diseases so difficult to treat.  But these guys believe they are on to something that can reset the switch, at least for some months.  And if they can reset it for diabetes, they may just be able to reset it for Peyronies also.  But, yes, feedback loops are occurring at every level and thats contributes to the complexity.

Another thing that is becoming known is the how the immune system itself gets distorted to cause these diseases.  Normally the immune system is a balance between T cells and B cells.  The T cells are the enforcers and the B cells are the detectives.  The B cells provide all sorts of false reports, but with a healthy immune system, the T cells are balanced between killer cells and regulatory cells.  The regulatory cells "check out" the reports and discard the false ones before the killer cells go into action sparing normal body tissue.  In the case of auto immune disease, two things happen.  One, the B cells take over and become more numerous, thus overwhelming the T cells with false reports, and two, the regulatory T cells become diminished and ineffective leaving the killer cells to reek havoc feeding on the false reports of the B cells which produce the antigens.  Additionally the memory T cells increase reducing the immune systems latency causing the problem to extend itself.  And the whole process feeds on itself.  (Pentox helps, in part, because it is a cytokine blocker and it disrupts immune system signaling.)  What is also known is that inhibiting the B cells temporarily causes the immune system to reset itself, after which it appears to stay normal indefinitely.  This research is in its early stages, but would be really cool if it pans out the way it seems to.  Right now they are trying to find a practical and safe way to temporarily inhibit the B cells.  This approach might cure a whole slew of incurable diseases if it works.  - George
Title: Re: Abstract on new proposed treatment method ...
Post by: George999 on December 22, 2009, 07:35:43 PM
Quote from: Uro Today

A novel modification of tunical plication by plaque thinning: long-term results in treating penile curvature of Peyronie's disease (http://www.urotoday.com/3351/browse_categories/peyronies_disease/a_novel_modification_of_tunical_plication_by_plaque_thinning_longterm_results_in_treating_penile_curvature_of_peyronies_disease__abstract12222009.html)

Penile tunical plication was performed, combined with plaque thinning with carbide burs, and 18 patients were available for a long-term follow-up.  ...  During the initial assessment after 6 months since surgery, complete straightening was achieved in 83.3% patients, and the residual curvatures in the three patients were within 20 degrees .  ...   After a mean of 50.5-month follow-up (range from 29 to 72 months), although 22.2% patients reported curvature recurrence, neither the recurrence nor the penile shortening affected coitus, and 100% patients were satisfied with the results of the operation.

Title: Re: Treatments on the Horizon ...
Post by: Tim468 on December 22, 2009, 08:41:35 PM
Interesting. It is a fancy and more surgical way of combining the Leriche technique with plication.

Tim
Title: Re: Treatments on the Horizon ...
Post by: Woodman on December 22, 2009, 10:24:50 PM
Would thinning the plaque before the plication procedure help to correct the curvature some? If so wouldn't that help save some penile length do to having to plicate less tissue to correct the remanding curvature?
Title: Stem Cells & Adult stem cell injections for Peyronie's
Post by: fubar on April 08, 2011, 09:00:40 PM
I have been reading about the use of ones own adult stem cells for healing. Seems that adult stem cell use is legal and used for diseases such as diabeties, heart disease and others.Today I found that a stem cell clinic treats Peyronie's. The California stem cell treatment center injects stem cells directly into the plaque for men wanting to avoid surgery.I do not know about them and there research or studies.But it did raise a brow.

You can read about the team and FAQs at http ://WWW.stemcellrevolution.com/Peyronie's _disease.html

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on April 11, 2011, 10:19:28 AM
Has anyone contacted this place? I sent a email and am waiting to hear back.
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on April 11, 2011, 12:46:54 PM
Rd

Just spoke to a woman on the phone.Did not keep her on it long though.She told me it is something new,  and have had good results.She said to fill out the application and someone will contact you.She also said the procedure is under 10, 000 dollars.I want to know more so I will apply to learn more.

Fubar ( this is not FDA approved )
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on April 11, 2011, 02:18:21 PM
Yeah I got a email basically saying the same to fill out the application and I would be contacted with more info, which I did. I am curious as to what good results they have seen and how much it is etc.
Title: Re: Adult stem cell injections for Peyronie's
Post by: Worried Guy on April 11, 2011, 02:34:09 PM
It sounds a bit dodgy to me!  I hope it is real as it seems a little weird we have not heard about it before.  Would they not be doing this sort of thing in University hospitals?
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on April 11, 2011, 03:10:58 PM
I heard back from them, below is the conversation. I am not sure about this place, I replied back to see if anyone has been treated yet because the website and email I was sent doesn't answer my questions.

ME:
Brief description of your problem injury or disease: At the begining of September 2010, I woke up with a lump on the shaft of my penis which is painful and uncomfortable a week later I was daignosed with Peyronies. I believe this was caused by injury during sex but am not 100% sure of this. I have no curve just a indent on the right upper side of the shaft. I was curious as to the treatment you offer and what if any results have been obtained.


California Stem Cell Treatment Center:
You certainly have Peyronies based on the description. What treatments have you tried already?
Stem cell therapy for peyronies is new and we do not have any data and therefore cannot make any claims about success, however, based on the ability of the cells to treat degeneration and create new blood vessels, we believe stem cell therapy may be beneficial to certain patients given our understanding of peyronies plaque on a cellular level.
Title: Re: Adult stem cell injections for Peyronie's
Post by: Worried Guy on April 11, 2011, 03:47:07 PM
These guys are bogus!
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on April 11, 2011, 03:55:01 PM
Worriedguy

Yeah having to pay for something not approved does not sound good.She said they had done 4 to 5 people.That it was something new they were doing .I do not know what to think of it.Definately not enough information to put money down for an injection.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: Worried Guy on April 11, 2011, 04:00:24 PM
Yeah, I bet it costs an arm and a leg also.  It's not FDA approved. 
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on April 11, 2011, 05:21:25 PM
Bascially it appears they want you to pay for the proceedure whatever that maybe and not give you any info on what it has done for the people that have already undergone the proceedure. Not a good selling point. I received my reponse from the Doctor him self, I googled him a bit has anyone heard of him good or bad?


Elliot Lander, M.D., F.A.C.S.
Boar Certified Urologist
Medical Director

Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on April 11, 2011, 07:14:06 PM
Rd

I haven't found anything bad about him yet.Went to healthgrades.Com,  he checks out so far.No malpractice,  sanctions or boards.I'm going to keep looking and read up on the Guy.I found another Guy before I found the California stem cell center that uses stem cells.So there are probably others.

It is good to know that they are looking for options in treating this crappy disease.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on April 11, 2011, 07:16:13 PM
I hope they are legit, just wish they would provide more info up front, cause if it works I'm in.
Title: Re: Adult stem cell injections for Peyronie's
Post by: nycsurfer on April 11, 2011, 07:20:58 PM
They did a 60 Minutes piece on these folks who claim that stem cells cure anything -- offering to inject it ost everywhere. "The whole thing is pretty much a crock" was the gist of the piece. I would run the other way.
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on April 11, 2011, 07:43:28 PM
Nycsurfer

I'm not running anywhere I have not ran to neprinol which claims to be a cure.I have not read or heard from them that there injections are a cure.Does not hurt to investigate, right?Seems that this whole business is a crap shoot.

I will look up the sixty minute piece.Maybe it is on you tube.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on April 11, 2011, 08:18:39 PM
I found the clips on youtube just put in 60 min stem cells. I think this maybe one what they are talking about just with out the promises.
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on April 11, 2011, 10:07:49 PM
I got another response from them concerning if they have treated anyone and the results. Still seems a bit shady

We just started our protocols and so far we have only treated a couple peyronies patients. Therefore, it is too early for results. We might know much more in 12 to 18 months. Peyronies is very troublesome and there are minimal effective options. We are hopeful that we will make a difference because of what we know stem cells are capable of but we are unable to promise anything at this time. In this early phase, we are offering treatment to patients interested in our experimental protocol (approximately 25 million mesenchymal stem cells injected into the
penis) at the reduced cost of $5,500. We are happy to be a resource for you as you explore all your options. Let Barbara Dunne know any time if you want to have a phone consult or see us in person. Best of luck,

Elliot Lander, M.D., F.A.C.S.
Board Certifed Urologist
Medical Director
California Stem Cell Treatment Center
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on April 11, 2011, 10:17:22 PM
Rd

It is media,  I do not trust them as I do not trust anybody.Being a member of this forum there are few members I trust also.Their are few and I'm sure they know who they are.Look we are but a number to anything but God.

We have to explore each and every avenue fore a cure.One bad apple does not mean they are all sower.The move On stem cell research for peyronie's is still positive .It is complicated wallet and soul.I have reviewed some clips and want to view more.

I have seen a man say i have seen about 200 stem cell centers pop up the last five years.Try to find them I'm not saying they do not exist. But really where are they.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on April 11, 2011, 10:27:24 PM
Very true I'm just frustrated with this disease and want it gone. I feel like I get my hopes up then let down. I hope this could be a actual working treatment. I'm going to continue to reseach this as well.
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on April 12, 2011, 11:35:25 PM
Rd

Today I watched Dr Jill helms of Stanford university speak and take questions.The content was about stem cell and tissue regeneration. IT was very extensive lasting 149 minutes on you tube.There seems to be alot of stem cell video.Interesting stuff you will learn alot.

Damaged tissue is the best treated in the acute stage because there is less scaring.The cells need to differentiate and be placed at the damage and stay where it is place.Injections are tough in doing this.There are risk such as cancer.Stem cells can morphasise into any cell changing in to that cell.I need to watch again to be sure.

Interesting but use of stem cells seem to still be in the early stages.So give it a watch when you have the time.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on April 13, 2011, 04:01:43 AM
Rd read more information on stem cell research and  watched  another video on on stem cell treatment that was used for a German Sheppard with hip dysplasia that heald well .The dog had been in much pain could not climb stairs,  get into vehicles or run.Know it can do all these things and run chasing  squirrels.Pretty impressive stuff.I found Dr.Lander had smother site WWW.landerUrology.com and saw him speak on you tube about other urological diseases.Could not find him speaking about autoglous injections I do know it is a Korean technique.

When I speak to him I want to as him about risk of cancer development and also its use for the diabetes and heart damage both that I have also.Whatch some testimonials on stem cell use for diabetes that seemed promising. Also  want to ask him about cost as it does seem alot cheaper than overseas.
I want to know how he places the stem cell with injection and are sure that they will soil and stay in place.What to expect from reduction in plaque and if new cells can restore this dammaged tissue as I believe through watching some video can be complicated or may not work on this.So basiccally I have been learning some but have been preoccupied in researching this and doing other things.

They stem cell technology has advanced 10 years in the last year.The Stanford piece was 2009 so I want to see the latest which one done 9 months ago.They even can take an adult stem cell am manipulate to an embryonic stem cell.
People are even saving the placenta and embryonic fluid to be stored for their children for future use.Crazy hugh,?

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: Luciano on April 13, 2011, 01:11:57 PM
@fubar
You are right that a lot has been done in this matter, but I still would be very carefull.
It is not because NASA was able to send someone to the moon, that I would buy a space-shuttle from a former NASA technician who tells me he built the one he wants to sell exactly the same way.

All of these are "NON official treatments" and the "Doctors" doing this, are sometimes more interested in your money than in your health.
Maybe there is someone out there that has the knowledge and knows what he is doing, but for Peyronies Disease you will probably be the first guinea pig he will test it on.

Luc
Title: Re: Adult stem cell injections for Peyronie's b
Post by: fubar on April 13, 2011, 01:27:54 PM
Luciano

Yeah I think it is at the Guinea pig stage with this Guy.His other site WWW.landerUrology.com say it is study and research I would not put out 10.000$ for something that did not have evidence in a positive way.according to the person I spoke to it has helped some guys.But that is here say.

I am waiting for a responce fro them as I filled out their application.Spending time learning a bout stem cell.It is pretty amazing science. So I will continue to get excited about it.From what I learned on you tube .Not sure if it could help Peyronie's out of the acute stage.Also there is a chance of cancer then ones penis would be in deep trouble.

I do not want to be a Guinea pig,  but I think xiaflex is a Guinea pig Study stage also.

Fubar
Title: Re: Adult stem cell injections for Peyronie's b
Post by: Luciano on April 13, 2011, 01:50:18 PM
Quote from: fubar on April 13, 2011, 01:27:54 PM

I do not want to be a Guinea pig,  but I think xiaflex is a Guinea pig Stuyvesant also.

Fubar
Yes but xiaflex it is a controlled study.. it would be like getting the xiaflex (product allready exists for dupuy contractions) and getting a compounding doctor to inject it for you. Not being sure of the dosage etc... thats what I call Guinea pig...
after a controlled study, i somehow feel safer.
L.
Title: Re: Adult stem cell injections for Peyronie's
Post by: Worried Guy on April 13, 2011, 02:35:12 PM
Also Xiaflex study is not the first trial.  We are now phase 3 I think and it has already been proven "based on the investigator's global assessment, 67% of subjects were very much improved or much improved after treatment with Xiaflex" in phase 2 with no adverse side effects. 
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on April 13, 2011, 04:21:22 PM
Worried Guy

I'm not trying to start a debate.From what I know phase three is the first study  use on Peyronie's disease.Dupytrens is considered closely related to the Peyronie's injury.Xiaflex was developed for dupytrens.Yes they are controlled studies.They do controlled studies on lab rats also.

I hope xiaflex helps and some say it is.I do not remember saying anything negative about the medicine.If you feel the use for Peyronie's not experimental so be it.I do not expect people to feel the same way, I do not argue that fact.

Fubar

Title: Re: Adult stem cell injections for Peyronie's
Post by: Worried Guy on April 13, 2011, 06:05:09 PM
Hey Fubar,

These are the results of the phase 2 trial

http://www.auxilium.com/ProductPipeline/PeyroniesDisease.aspx

They are not that detailed and I would like to see the actual study in full.

I think stem cell could be a valid choice in the future but i'm just not sure that it is there yet as far as technology goes.  I think it is something to watch closely but can't help feel that Lue, Levine and Ralph here in England would have funding and be doing studies on it right now if it were.  I could be wrong.

Title: Re: Adult stem cell injections for Peyronie's
Post by: MikeSmith0 on April 13, 2011, 07:51:32 PM
This seems like it could be a nightmare if the injected cells decide to turn into anything but healthy tunica tissue...what if they die or cause more scar tissue and inflammation?  They could turn into nodules, etc... who knows?  It's not clear how this could cure Peyronies Disease...just randomly injecting stem cells and hoping they'll figure out what they need to do... they act like they are nanites from star trek.  (Seriously - one of my favorite episodes too: http://memory-alpha.org/wiki/Nanite)
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on April 13, 2011, 08:06:28 PM
Man I did not mean to create a monster when I made this a topic. I vaguely described that these are some concerns.Research is moving a lot faster in stem cell research than Peyronie's. By the way you already have nodules in your penis from Peyronie's,  vepramil injections and so on.

Hell I have fatty deposites throughout my body and I'm skinney.Lumps and bumps such as life.Might be good if you look into it some more they can use healthy stem cells from the same tissue that is non diseased.look I really do not know much about it.But what I have learned is remarkable.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: MikeSmith0 on April 13, 2011, 08:20:28 PM
It could have promise at some point - I'm glad you posted it - my comment wasn't in response to your post really.. more in a response to the FAQ and vagueness on that site.

I don't think we know enough about stem cells yet to just inject them.  Dr. Perovic in Serbia would seed a PLGA scaffold with plasma and then implant that into your penis to enhance girth (which would be "natural" since it came from your own cells plus the scaffold which disintegrates)... sounds like is a stem cell kind of thing... not sure what the results are like though from his patients.  He passed away but another doctor is doing the surgery now.
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on April 13, 2011, 08:32:41 PM
Mike

From what I have learned from watching my first Stanford seminar.I would not let anybody inject me without knowing it was going to work.I encourage you however to you tube this. I believe it does give hope in the future.It seems like everything with this disease is up in the air.

I want to think that this science will work for us and everyone troubled with diseases and I have more than one.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on April 14, 2011, 01:08:33 PM
Yeah this seems like it's in the very early Guinea pig phase. I think they are basing this treatment off scaring from heart attacks. I have read they have used stem cells to reduce/eliminate scaring after having a heart attack. Apparently the stem cells take root and regrow the correct tissue and veins to support it.
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on April 19, 2011, 12:42:54 PM
To all

I mentioned to bring this up as topic not a resolution!

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: fireguy on April 20, 2011, 07:31:10 PM
I am reading this post with a wait and see attitude. Being fairly new to the disease I have been doing quite a bit of reading and planning my attack on fighting it. Stem cell may offer some hope in the future, but it is too early to tell. The fact is there is little to no funding in researching Peyronies disease because it affects such a small percentage of the population. If stem cell does prove to be helpful in the distance future, it will be a result of some other problem being repaired and this being an off chute of that result. I do hold out some hope that the medical community will one day help us, but I believe that it will take someone with great power in the medical field being affected by peyronies for funding to come forward.
In the mean time we are the Guinea pigs. If we all work together and share information like this form is doing, we may strike gold one day. Keep on beleiving
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on August 10, 2011, 04:31:21 PM
I just want to let everyone know I just had the procedure done at the California Stem Cell treatment Center. I know most of you all believe it to be a scam but after doing much research I took the plunge, I actually just got back to the hotel. I had a pleasant experience and the staff was more the welcoming and willing to answer all my questions. The procedure wasn't that bad 30 min for the mini lipo and about 15 min for the injections. They harvested 19 million stem cells and injected it to and around my plaque. They said from what they have seen doing this procedure that it is more effective on the early stage/active stage of the disease which I am in. They said to give it 3 months for any results. After all was done the Dr actually drove me back to my hotel. I will let you know any results I see. They still do not promise any results as they say this is new and they just don't know enough about how all this works but are optimistic. If I have good results I will let everyone know, if I do not I will let you know so that no one else bothers with this procedure.
Title: Re: Adult stem cell injections for Peyronie's
Post by: mike67 on August 10, 2011, 04:54:51 PM
rd
We are all  thankful that you took the time to report on your "ground breaking " or should we say " Plaque breaking " Stem Cell treatment. I have got to hand it to you rd , going to Beverly Hills for this treatment. I recall phoning them back in April after looking up their web site . Fubar had alerted me to this treatment.
I am going to our initial Canadian Peyronies Disease Support Group meeting this evening in Hamilton and will table your report as a great point of interest in available treatments.
Many members are no doubt anxiously awaiting your progress reports.
All my best wishes for a positive outcome.
Mike67
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on August 10, 2011, 11:46:15 PM
Rd

I am thankful you decided to post this today as you pm'd me earlier and said you wanted to wait.Wow you have balls man, you have pioneering in your blood.I remember I think it was last April you telling me if you did not see progress that you were going to give stem cell a try and  you did.

I remember starting this thread with mixed emotions amd watching it come to a hault.You jumped in and did more research and had the treatment. Wonder if you will share some of your knowledge?

I brought the California stem cell to the forum.I hope I won't regret that.I wish you the best and that you get relief from the Peyronie's symptoms all together.I admire your bravery as many might think you are crazy for doing this.I'm sure you thought long and hard about this.

Please keep us informed and thank you: fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on August 11, 2011, 08:17:37 PM
Just got back home from Cali, swelling has gone down a bunch. I have no pain to speak of. I don't know if this is because it is swollen or not. I constantly had weird annoying and uncomfortable feelings while flaccid the majority of the time before this treatment unless I left it alone and by alone I mean no touching the area even being careful not to touch the area while going to the bathroom. The doctor did tell me that I probably wouldn't have any discomfort because the stem cells have a anti inflammatory effect.
Title: Re: Adult stem cell injections for Peyronie's
Post by: saramon on August 11, 2011, 09:33:52 PM
Gutsy effort RD, I'm impressed.

I hope the results meet your expectations.

Having just completed the xiaflex trial I know what it is like waiting for something / anything to happen.

Did they do any "before" measurements on you and do you have to go back for any check ups.

Thanks
S

Title: Re: Adult stem cell injections for Peyronie's
Post by: ComeBacKid on August 12, 2011, 02:52:57 AM
RD,

Did insurance cover this? What kind of price tag is someone looking at for this?  Keep us posted!

Kid
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on August 12, 2011, 07:39:41 AM
Saramon

They didn't do any before measurements, because I didn't have a curve just a dent and pain. Because I live on the east coast and can't afford to go back and forth for follow ups they will check in by phone and email to check my progress and to keep me from having to fly back out. They said that they want to see how things go over the next 3 months which I should see results if I am going to have any by then. They said that's how long it typically takes the regeneration to happen.

Comebackkid

Insurance did not cover this as it is experimental. The cost for the peyronies treatment is $5,500.00. It is expensive but I felt it was worth a shot. I haven't had any pain or discomfort yet since the procedure I thought I would have some because of the injections in and around the plaque but none so far which is great but I just had it done wed afternoon so I will keep you all posted. I still have swelling but it keeps going down and is almost gone. The only thing that I notice is I do have soreness around the mini lipo area which is to be expected.
Title: Re: Adult stem cell injections for Peyronie's
Post by: UK on August 12, 2011, 08:48:29 AM
Thanks for sharing your experience, fingers crossed for you.

One question I did not see asked was where do they extract the stem cells from , which part of the body?
Title: Re: Adult stem cell injections for Peyronie's
Post by: GS on August 12, 2011, 11:09:32 AM
RD,

I certainly hope this works for you.  If it does, I bet there will be many of us follow your lead.  I know I will be one of them.

Please keep us all updated as often as you can; I hope this will be a very exciting 3 months.

GS
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on August 12, 2011, 11:15:52 AM
Quote from: UK on August 12, 2011, 08:48:29 AM
Thanks for sharing your experience, fingers crossed for you.

One question I did not see asked was where do they extract the stem cells from , which part of the body?

They usually do it from the mid section, but as soon as they saw how lean I was they decided to take it from the love handle area. I've always had very low body fat and last time I had it tested it was 3.9% I am always active and have a super fast metabolism and the part that had the most fat was my sides so that's where they took it from well just my left they didn't need to do my right as they got enough of the cells from the one side.
Title: Re: Adult stem cell injections for Peyronie's
Post by: restore on August 12, 2011, 12:21:25 PM
rd, I haven't researched it much, but do they extract just the stem cells from the fat cells they remove from the donor site?  I suppose that's why the price tag, they have to separate the stem from the non-stem cells in a lab environment. 
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on August 12, 2011, 12:40:35 PM
Quote from: restore on August 12, 2011, 12:21:25 PM
rd, I haven't researched it much, but do they extract just the stem cells from the fat cells they remove from the donor site?  I suppose that's why the price tag, they have to separate the stem from the non-stem cells in a lab environment. 

That's correct, after I had the mini lipo I had to wait aprox a hour for them to seperate the stem cells from the fat they extracted.
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on August 13, 2011, 12:14:30 AM
That price tag is cheap if it is successful ! Really do not get so excited.There is alot that can go wrong that is why I stoped posting on my own topic.Still I feel more interest in my own body repairing its self with my owm stem cell than xiaflex.

Companies,  scientist, government,  Companies own us money, money, money if you have money there it is.People. like are rd are more than money if it is real.I tend to trust nobody.But on a time date he's on the rule.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: crashbandit on August 14, 2011, 06:35:43 PM
Quote from: rd on August 12, 2011, 07:39:41 AM
Saramon

They didn't do any before measurements, because I didn't have a curve just a dent and pain. Because I live on the east coast and can't afford to go back and forth for follow ups they will check in by phone and email to check my progress and to keep me from having to fly back out. They said that they want to see how things go over the next 3 months which I should see results if I am going to have any by then. They said that's how long it typically takes the regeneration to happen.

Comebackkid

Insurance did not cover this as it is experimental. The cost for the peyronies treatment is $5,500.00. It is expensive but I felt it was worth a shot. I haven't had any pain or discomfort yet since the procedure I thought I would have some because of the injections in and around the plaque but none so far which is great but I just had it done wed afternoon so I will keep you all posted. I still have swelling but it keeps going down and is almost gone. The only thing that I notice is I do have soreness around the mini lipo area which is to be expected.

Wow, you took that plunge with no curve or loss or size. But I guess that scary plaque you have made you do it ultimetely. Would they do this treatment with no plaque? How bad was your pain level rd? How big is your plaque and dent?

Thanks for keeping us in the loop rd.
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on August 15, 2011, 10:37:06 AM
My pain was pretty bad, in the beginning it was hard to wear pants and underwear. The seams would touch the plaque and cause great pain and even if it wasn't touched it would throb. I did find eventually though that if I just didn't touch the area at all the pain would go way down. I would still have uncomfortable feelings but no where near if I touched the area. My dent changed over the 11 months. It started as a bulge right near the head on the right side then changed from a bulge to a decline about a inch long. Sex would leave me in pain for days after and masturbation the same. The dent then changed to a S type curve so that where the plaque was it would decline then incline again. I could feel where it would slope down then back up. As long as I avoided touching the area I was OK not pain free but dealable. The Plaque started out as a riced shape then got bigger almost into a diamond shape. Then eventually broke into 2-3 peaces. Sometimes it was bigger and sometimes it felt smaller so not sure what to really tell you about the size as it seemed to change. The reason I did it was because I had stopped all dating, because with the pain I didn't want to have sex even though I love it. It was really effecting me emotionally and that's another reason I stopped dating and went forward with the procedure. So far I have been pretty much pain free with an occasional sting feeling that might pop of for a second or two then go away. I have been keeping away from the area as well. But it feels like it is a little better although it is to early to tell. The bruising continues to go away and where the injections were made is almost back to normal size /swelling lessening. I'm not sure if what is left is swelling to be honest as they did injected a lot into of stem cells and liquid into that area and maybe thats what I am seeing as swelling, all though it going back to normal size as the days go by. I've also had erretions which haven't hurt either. I never had a problem with pain and errections my pain was always flacid and didn't change with errection. Another reason why I did it was because of the research I did, I kept finding people using stem cells to repair damage areas of the body such as for damage after heart attacks, ance scars, hip displysia in dogs, etc. Most of the negative stuff I found on it was based on fears of cancer developing or just not knowing enough about them yet. I haven't had cancer that I know of and I wasn't really concerned with that happening. Plastic surgens have started using it in a lot of the proceedures for cosmetic reasons where they implant fat to fill area's and the stem cells help the fat to stay and take root and grow more. So this is why I didn't fear it causing cancer.
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on August 18, 2011, 02:13:19 AM
Rd

Have they offered a follow up or treatment as well? Do they want to see you again and evaluate?

How many releases of liability did you have to sign.


Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on August 18, 2011, 10:59:31 AM
Quote from: fubar on August 18, 2011, 02:13:19 AM
Rd

Have they offered a follow up or treatment as well? Do they want to see you again and evaluate?

How many releases of liability did you have to sign.


Fubar

The paper work wasn't bad at all. I sat down with the doctor went over everything then signed in a few places and initialed in others. Some of it was permission to photograph which I said no to, the other was are you willing to talk to others about your condition then the standard leagal stuff.

I received a call Monday to see how I was doing and she said she will send me a questioneer in a few weeks to fill out. Dr Lander said that once I hit the 3 month mark if I have had results that we can discuss a follow up treatment to further any results I see. If I don't have any results then there will be now follow up treatment. I mean I guess I could always insist on one but if it doesn't work the first time I'm not going to try it again.
Title: Re: Adult stem cell injections for Peyronie's
Post by: Worried Guy on August 18, 2011, 12:53:55 PM
Would a follow up session mean another 5k?
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on August 18, 2011, 01:05:20 PM
Quote from: Worried Guy on August 18, 2011, 12:53:55 PM
Would a follow up session mean another 5k?

I would assume so, I didn't go into details about that because I wanted to see if I get any results first. I know they are talking to other companies and trying to arrange for stem cell banking where you can have them stored and grown for future treatments. This isn't in place yet but once it is I would imagine this would drop the cost of follow up treatements as they don't have to harvest them or run them through the process of seperating the stem cells from fat. All they would have to do is grow more from the store and inject them.
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on August 18, 2011, 01:15:31 PM
Rd

Yeah if it does not work the first time.Why spend more money.Lets hope for good results.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: Ben on August 27, 2011, 04:06:44 PM
I recently had a discussion with my psychiatrist about stem cell. One of his patient travelled to germany to try a cure for multiple sclerosis. She had no result eventhough the doctor made her some realistic promises.
The lab is closed now. It was called stem cell center if my memory is OK.
Title: Re: Adult stem cell injections for Peyronie's
Post by: newguy on August 28, 2011, 12:02:28 AM
Thanks for the update rd. You're a brave man to take a plunge like this, but it's of course very interesting if it improves your condition. I only just realised that this thread had come back to life!
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on October 18, 2011, 12:08:20 PM
Just wanted to give everyone a update as it has almost been three months since I had the stem cell procedure done. They said I should notice something by 3 months if it is going to give me any results at all. I have been leaving the area alone for long periods of time and just checking it everyonce in a while. Last night while checking out the plaque I couldn't locate the bigger of the two plaques I had. This is the same plaque they put more focus on during the procedure because it was bigger and harder. I still have discomfort and hour glass deformity because of the remaining plaque but not being able to find the other one was really surprising and encouraging. I am going to wait till the end of october/begining of november to re examine my plaque to see if it remains gone. My plaques have fluctuated before and started off as one big plaque which broke into two peaces and actually felt like three peaces at times.
Title: Re: Adult stem cell injections for Peyronie's
Post by: crashbandit on October 20, 2011, 06:38:09 PM
Thanks for the update again rd. That's a good sign that a lump has disappeared.

I hope your on pentox? What other treatments are you doing? I think what ever you can do to help the stem cells to do the repair would be a good thing. Of course to be careful not to interfere with the stem cell repair.

If I were you, I'd be on pentox, with some low-dose cialis (if no problems with ED) and some light sexual activity if you can. Also a healthy diet and no smoking and such.
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on October 20, 2011, 07:42:41 PM
Quote from: crashbandit on October 20, 2011, 06:38:09 PM
Thanks for the update again rd. That's a good sign that a lump has disappeared.

I hope your on pentox? What other treatments are you doing? I think what ever you can do to help the stem cells to do the repair would be a good thing. Of course to be careful not to interfere with the stem cell repair.

If I were you, I'd be on pentox, with some low-dose cialis (if no problems with ED) and some light sexual activity if you can. Also a healthy diet and no smoking and such.

I actually stop pentox because I wasn't sure what effect if any it would have on the stem cell procedure. I am only taking COQ10 one a day. I am eating healthy and cut as much processed foods as possible. I eat a lot of fresh fruits and vegetables during the week and i eat what ever i want on the weekends. I work out regularly 5 times a week cardio and weight lifting. One thing I started doing more of is stretching and maybe I'm imagining things but when I do a sit and reach to stretch out my hamstrings and lower back I sometimes feel a weird feeling in my plaque tingling kind of. I'm hoping that the plaque stays gone as before the stem cell treatment sometimes my plaques felt like they were shrinking one day then another they felt like they were at there biggest. I try not to touch the area much the less contact I have with it the less pain and discomfort I have. I will keep everyone informed though. Hopefully the one plaque will not reappear and the other one will go away as well.
Title: Stem Cell injection as possible peyronie's cure ???
Post by: Pat_Hos on October 23, 2011, 03:09:49 PM

Is any mecical expert currently studying injecting our own stem cells back into one's own penis in order to reset the clock to our orignial penis condition?  They are using this technology on so many other body parts; why not a penis?  If they inject stem cells from another person there might be rejection issues and life-long anti-rejection medication, but using our own penis cells might promt a regeneration of the damaged area back to its pre-damaged condition.  Which doctor in the world is in the forefront of using stem cells?  Perhaps he or she might be open to studying a cure to another body part.
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: George999 on October 23, 2011, 03:43:12 PM
Very, very interesting indeed.  These guys are the world leaders in the field right now -> http://www.regenocyte.com/ (http://www.regenocyte.com/)

I have been watching them for a while now and thinking to myself about application to afflictions like Peyronie's.  - George
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: mike67 on October 23, 2011, 05:20:26 PM
RD ( check his August 10/11 post) was the first Forum member , I believe , to undergo this treatment. He went to the California Stem Cell Treatment Center . He has been providing excellent follow up posts.
Now we seemingly  have a possible alternate choice on the east coast . From what I understand it is still experimental for Peyronies , but isn't almost everything we are trying more or less experimental ?

Still - the use of stem cell therapy may be just the ticket we have been waiting for.
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: fubar on October 23, 2011, 07:10:45 PM
Mike67

When i created this thread iput it out there as experimental.If this.does provide relief.Then we owe alot of gratatude to rd.There can be alot of complications durimg an experimental stage.

With out a doubt this is the futer for us,  regardless of rd's outcome. I know he belieaves this also and has taken the risk.Dr alata that has know affiliation with this treatment is the formost person fighting for a treatment in this disease as he created a team or it started as his general attempt.

In his progress he has expanded at other urology problems with children and peoples that need new bladders.He is the formost specialist and scientist that can help us.

Read about his efforts on the web, and think about reaching out to him as his first intentions were to correct Peyronie's.  If you decide to learn about what he can do,  the things you read will give you hope.We need to push him though.

Fubar

Ps he is a rock star in his in devours.
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: mike67 on October 23, 2011, 08:02:34 PM
Fubar
I'll look him up as you suggested.  Thanks pal.

Mike
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: mike67 on October 23, 2011, 08:07:32 PM
I'm looking but can't find Dr. Alata. Where do we go to find him?
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: George999 on October 23, 2011, 09:02:58 PM
Regenocyte, while having offices in Florida, actually does their procedures in the Dominican Republic.  CSCTC, on the other hand, is entirely US based.  Also, CSCTC seems to have more experience treating Peyronie's while Regenocyte is focusing on cardio and pulmonary applications.  At this point, I would go with CSCTC since they are using qualified urologists specializing in this approach.  At this point there are a number of other practitioners doing stem cell work, each group seems to be specializing in different niches.  For sure, this may well be the future of medicine when it comes to treating degenerative diseases.

I might add that I don't think this is a scam at all.  I think it is treatment with a lot of promise.  The reason it is not FDA approved is that it is experimental and the FDA does not approve experimental treatments for obvious reasons.  Even if the FDA views treatments negatively, that does not necessarily mean they are scams.  There is a lot of politics and money involved in medicine and not all FDA positions are as science based as they would have you believe.  There are huge amounts of money being made on treating incurable degenerative diseases.  Imagine the financial loss that would be created were something like this to be perfected to the point of producing a cure.  There is plenty of reason for vested interests to create as much opposition as possible to emerging therapies with potential for curing these scourges.  Additionally these stem cell operations are very up front about not making any promises.  If you choose to participate you ARE a guinea pig.  But there is enough success happening out there with stem cell treatments to justify optimism.
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: fubar on October 24, 2011, 02:24:28 PM
Mike

That would be Dr. Anthony Atala i can see i made several spelling mistakes yesterday ,sorry.You can find a lot about him on the internet.I have left his address in the awareness board some time ago.I believe someone posted his address before me.Comback sent him a letter a while back but never heard back from him.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on October 24, 2011, 02:34:15 PM
Rd

Does your regular doctor know that you have had stem cell injections?Might be a good idea to let him know if he does not.I would ask him if pentox or any other suppliment would aid the process.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on October 25, 2011, 09:57:30 AM
Quote from: fubar on October 24, 2011, 02:34:15 PM
Rd

Does your regular doctor know that you have had stem cell injections?Might be a good idea to let him know if he does not.I would ask him if pentox or any other suppliment would aid the process.

Fubar

I spoke to my GP about the proceedure to get his input he was honest and said he didn't know much about stem cell proceedures but to be careful in making the decision. He did ask a lot of questions though opposed to the urologist I went to who was horrible. I told him how uncomfortable it was and how when I sit in a car I always have to adjust because of the discomfort and he immediatly dissmissed me saying oh everyone does that. I told him about the stem cell proceedure and he immediatly dissmissed it claiming it was a scam without asking one questions. I understand if he doesnt agree with it but I didnt tell him anything other then I had read about a new place in cali performing a experimental stem cell proceedure to see the results on peyronies. Also as for pentox and asking my GP, he wasn't to familiar with Pentox so asking him would probably not give me any answers as to the effects of pentox and the stem cell proceedure. I will not go back to the urologist as all but one seems to boast about how they are experts and nothing works but shoot down anything you ask or bring up as alternative treatments, atleast thats been my experience. I could probably send a email to the stem cell center but another reason I stopped was because I didn't want to be on both and if they resovle not know which treatment actually cause the healing or if it was a combination of the two. I check the lump out again and I still can't find the second lump which is good. The first one might be a bit smaller but im not sure. I think come three months time I shouldn't expect anymore results as I would think 3 months should be more than enough time. I also can't afford a follow up treatment should the one lump remain. But I will keep everyone posted.
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: Pat_Hos on October 25, 2011, 10:17:58 AM
Fubar and all,
Thank you for the responses.
I appreciate all of the information which has been pointed out on the subject; I did not know there was a previous discussion-thread on the topic.  I wish there was more information on the results of the treatment from the stem cell shots one guy (Rd) already had; I suppose it is too soon to know if it will work since Rd just had the shots a few months ago.  I looked up the doctor Fubar mentioned and would travel to have treatment, but someone mentioned he had tried to contact the doctor but received no response.  I am sure the doctor is inundated with requests regarding treatment on a variety of different organs, probably bladders and kidneys get the most requests due to the shortages.  Compared to those people, we should feel fortunate.  Someday I hope to recover from this nightmare and gain back what I have lost.  In the meantime, I hope to lose no more length and girth.  I have had this since 2006 so it is going on 6 years, I hope that long length of time does not lock in the damage.  I been taking Vit E for nearly six years and have been on Pentox two to three times a day for four years, still just more shrinkage and I find Dr. Lue to really offer little information, just his same jokes each time.  I have not tried a VED since the time required sounds gruesome.  The traction device just made things worse, I tried it for a year and that is when all of the shrinkage began, I must have been doing something wrong and caused the opposite reaction as now it is difficult to stretch.  I certainly hope that stem cells work as our own bodies probably offer the best hope to reverse this damage.
Pat_Hos
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: KAC on October 25, 2011, 11:07:26 AM
Pat_Hos:  Thanks for your post.  It's not exactly encouraging news, but I think it helps to just know the facts of different experiences.  I've wanted to be somewhat scientific in my approach as I keep trying various strategies to deal with this disease.  My actions have been to try everything, sometimes all at once, to see what will help.  For a while I was getting worse, no matter what I tried. Now I seem to be getting better without really knowing what, if anything, is helping.  For a while I was convinced that VI injections were making things worse.  Now I'm trying them again, and they seem to be helping--but I'm not sure.  But I think one way we can all help each other is just by putting our various experiences out there, so we can at least take it all into consideration as we are making decisions. 
Title: Re: Adult stem cell injections for Peyronie's
Post by: George999 on October 25, 2011, 09:55:50 PM
You know, I think a LOT of doctors are cynics to the extreme.  As far as they are concerned, if they don't have anything in their arsenal of pills that will help, NOTHING will work.  And they really don't want you to discover something else because they want you to keep being a good customer and buying their pills.  Of COURSE they don't SELL the pills themselves, BUT they get under the table compensation for prescribing lots of them.  I suffered for years with an "untreatable" urinary tract problem with urologist after urologist telling me there was no solution known to man for it.  And they all, TO THE LAST ONE, "knew what they were talking about".  And then I got a young urologist who obviously hadn't learned how to handle these things and he said to me "***, why on earth haven't you got this fixed?".  He then said they had been fixing this problem for people for years and referred me to a research center and the problem got solved quickly and easily.  AFTER doctor after doctor told me that it was unfixable, the result being one expensive procedure after another every three or four or eight months or so however long a treatment might last.  They were making their money and they didn't want me to get a permanent fix and leave them without income.  NONE of them said "I will check to see if there might be a treatment out there that I don't know about", NOT ONE.  It is very infuriating.  Your GP is  a very good guy but the uro is typical and disgusting.  How can all of these doctors be so arrogant and greedy.  - George
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on October 26, 2011, 12:09:42 AM
Guys

My head feels like a bag of marbles at the moment.Hard to keep one thing in focus when none is a sum of cures.Look supposedly we have thousands of guys on this forum with this crippiling disease.We have advocates for certain therapys  with suppliments , devices and injections of chemical and human tissue.

Stem cell seems to be the baby with one member recieving injections three months ago.This forum and the old forum combined i believe to be seven years old.Someone please correct me if i am wrong.

This forum surviving on this subject this long tells me the members and the forum can make difference.I have noticed many new comers posting i find this comforting and saddening.

Shows our comunity is growing at a rapid rate and threads are becoming more complexed than the operation of those answering questions and appropriating directions to main threads.

Not to get off topic but i learned today that big (to) terrell owens formally a Dallas Cowboy.wide reciever was showing his wares after having knee surgery and having stem cell treatment in korea.The man looked great and if my penis was half the shape his knee was in my life would be complete i would retire.

Not retiring my penis it would definitely have a schedule.I would retire the knee after making me millions.

Fubar

Title: Re: Adult stem cell injections for Peyronie's
Post by: ComeBacKid on October 26, 2011, 02:16:58 AM
Fubar,

Keep up the good work!  Keep sending out those letters I gave you!  We have to look to the future!  New treatments are popping up all around us, we are on the track to being healed...

Comebackid
Title: Re: Adult stem cell injections for Peyronie's
Post by: 0x5555 on October 26, 2011, 02:27:15 AM
A lot of the new posts are probably higher ranking in Google when you search for 'Peyronies'.  This place is one of the few non-BS sites when it comes to the disease.
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on October 26, 2011, 02:32:32 AM
Ox

Sure got it right this is your one shop place.There are many her to help the weary. 24/7 some one is here.

Fubar
Title: Re: Treatments on the Horizon ...
Post by: George999 on November 04, 2011, 11:36:49 AM
Stem cell therapy rejuvenates tissue by overwhelming sick cells with new healthy ones.  Here we see the opposite approach, rejuvenating tissue by removing unhealthy cells by brute force.

http://www.cbsnews.com/8301-504763_162-57317606-10391704/ridding-body-of-old-zombie-cells-slows-aging-process-study-shows/ (http://www.cbsnews.com/8301-504763_162-57317606-10391704/ridding-body-of-old-zombie-cells-slows-aging-process-study-shows/)

It would be very interesting to see what effect this might have on Peyronie's once they get it out the door.  - George
Title: Re: Adult stem cell injections for Peyronie's
Post by: Gap on November 09, 2011, 02:04:44 PM
Anything new on this? I would sure as hell travel to Korea if that were my last option, bc the meds aren't working and Lue seems to think that no one will operate.
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on November 09, 2011, 02:25:30 PM
The only news I have to report so far is that I contacted the center to inform them of the results I have seen, and to ask if I should expect to see anymore after having had the procedure 3 months ago. I also was curious as to follow up treatment price. Not sure I will get another treatment as I don't have the money and would have liked the first to have better results then what I have experienced so far. But here is the doctors response.

"I think regeneration can occur for several months. A second treatment may be required for the second plaque but I would wait at least 6 to maybe 9 months before that to be sure it is absolutely necessary. The resolution of the first plaque is encouraging. For a second treatment we would discount the price to $3500."

One note about the I think regeneration... comment, they did explain to me that this is new and experimental and that they are still learning a lot about stem cells hence the I think comment. The original procedure was $5500.
Title: Re: Adult stem cell injections for Peyronie's
Post by: Gap on November 09, 2011, 02:46:36 PM
Thanks RD - I'd love to have something to hold onto. It doesn't seem like I am a good candidate for surgery, even though I was told that was my only option, and I don't react well to Pentox.
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on November 09, 2011, 04:00:38 PM
Yeah I know what you mean about something to hold on too. The only other thing to is this is so new atleast in the US I had a long conversation with Dr Landers who did my proceedure he said there is still so much to learn that have barely scratch the surface with stem cells. I hope to get more results and not have to do a follow up, if I had the money I probably would give it one more try to see if any further results come from it. I'll have to see in 9 months where I'm at and evaluate then.
Title: Re: Adult stem cell injections for Peyronie's
Post by: Gap on November 09, 2011, 04:24:52 PM
Does insurance cover it?
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on November 09, 2011, 05:10:26 PM
Nope because its not an approved treatment.
Title: Re: Adult stem cell injections for Peyronie's
Post by: Gap on November 09, 2011, 05:50:45 PM
Well, let me know how it works for you in the end, because no solution is not a solution regardless of the price.
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on November 15, 2011, 12:25:41 AM
RD

We have exchanged many pm's about this subject.Probably much less than some.I was thinking about you today.Your decision on taking on the treatment and why.Realizing we both want to cut to the chase.What we have learned and.whatis nested from discovery and pecking at the forum.First thing in mind do i react suddenly to everthing or bide my time.You reaction like mine is with time their could be a small window of time with a first cell treatment for.our problem.You decided to take this treatment while you where in the acute stage.As i read about the autoglass stem cell treatment.Finding that the treatment is better off during the early stages. This leads me to believe better results.

I think that peyronie's in a more mature stage meaning beyond the acute can cause more significant troubles such as cancer.Your postings and history of you treatment is of the most importance on our.platform as you are our first.

Personally i am hesitant to have the treatment as i am past the acute stage.Finding things are changing all the time.From my understanding could be dangerous with old scar i am feeling my lumps.

Anyway my friend i have been trying to take a break but find the compulsion to arrive here again.

Please keep us posted and stay strong.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on December 07, 2011, 03:35:45 PM
Just a quick update, I think the remaining lump on the right of my shaft might have gotten a bit smaller but just a bit. I had also tried stretching the area out by bending my penis while flaccid away from the lump and feeling some stretching sensations. However I have discovered another small lump on the opposite side of my penis in the area where it was being bent towards while stretching the lump on the right side of my shaft. I'm not sure if the stretching caused it or not. I don't really feel anything from it unless I have an errection which I feel some tightness very slight discomfort out of it. I have stopped trying to stretch any of it out, thinking that might have caused new lump. I plan on leaving it alone again for a while and checking on it once a month. I am considering in 6 months maybe trying a follow up treatement with the stem cell center because of how the larger of the two original lumps on the right side of my shaft now seems to be gone. My only fear is that if something as simple as stretching caused a new one does this mean any new stress on my unit will result in more lumps? If that's the case something else is still wrong causing any stresses to turn to lumps.
Title: Stem Cells and Peyronie's treatment
Post by: Skjaldborg on January 23, 2012, 10:30:54 PM
Huffington Post isn't the best source for science news but this story is relevant and encouraging:

http://www.huffingtonpost.com/2012/01/23/stem-cells_n_1224764.html

Stem cells sure are versatile. They're being eyed as the key to treating medical conditions ranging from heart disease to neurological problems and blindness.

Can stem cells make a better mousetrap? Maybe not, but a provocative new study shows they're capable of making something even more impressive:

A better rat penis.

And while rats might not care, urologists say the feat could be very good news for men suffering from Peyronie's disease and other deformities of the penis.

For the study, published online in Proceedings of the National Academy of Sciences, researchers led by Tulane University urologic surgeon Dr. Wayne Hellstrom tested tissue grafts on rats whose penises had been surgically scarred.

One group of rats got conventional tissue-only grafts, another grafts that had been mixed with stem cells taken from their own bodies, ScienceNOW reported. A third group underwent so-called "sham" surgery that didn't involve a graft, and a fourth group got no treatment at all.

What happened? When tested eight weeks later, the rats that got the stem cell tissue-grafts showed better healing and better sexual function than rats in the other groups.

What's the next step? Hellstrom said he and his colleagues would test the technique in primates and eventually in humans, according to ScienceNOW. "Peyronie's affects 3% to 9% of adult males and causes a lot of psychological distress," he said. "If we can improve what we have now, it seems like the logical thing to do."

No word yet on that mouse trap.
Title: Re: Adult stem cell injections for Peyronie's
Post by: james1947 on January 24, 2012, 03:31:06 PM
RD
Can you update the forum if have some improvement from your last update?
Have some improvement in girth and length?
Thanks
James
Title: Re: Adult stem cell injections for Peyronie's
Post by: UK on January 25, 2012, 06:22:55 AM
Quote from: fubar on November 15, 2011, 12:25:41 AM
I think that peyronie's in a more mature stage meaning beyond the acute can cause more significant troubles such as cancer.
Fubar
this is a reckless comment, no evidence whatsoever, and no need to scaremonger. You are good poster but I'm sure you'll agree not helpful.
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on January 25, 2012, 08:24:37 AM
Quote from: james1947 on January 24, 2012, 03:31:06 PM
RD
Can you update the forum if have some improvement from your last update?
Have some improvement in girth and length?
Thanks
James

Nothing really to report since my last post. I am considering a second treatement, I contacted Dr Landers and he said to wait atleast 6-9 months from the original treatement to do a follow up. I am considering a follow up because of the fact that one of the lumps treated is gone and the other seems to have slightly improved. If the one lump hadn't gone away I would write this treatment off but because it did is the only reason why I am considering a follow up. I wish I had more to report and if anything changes better or worse I will be sure to update.
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on January 25, 2012, 02:26:35 PM
UK

Agreed not an awesome post.However it is true that treatment with stem cells with old scar tissue can and does become cancerous.I found this information on you tube, some seminar on stem cell treatment at a university.

They found stem cell treatment more effective with new wounds compared to old wounds.With the old they found that they could become cancerous with hair and bone,  and tumors growing .

I am sure that anyone of us could find this evidenced if one was inclined to do so.It would be reckless for one not to mention that this is a risk in stem
cell treatment.I do agree that post was vague and came across as an opinoin.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: james1947 on January 25, 2012, 02:59:24 PM
Fubar
Can you give us a link to the you tube?
Thanks
James
Title: Re: Very new study: Stem cells succeeds 100 % to treat peyronie's disease in rats
Post by: james1947 on January 31, 2012, 05:37:10 PM
ak123
Appreciate  your research, maybe this treatment is the future.
All the articles are the same, publishes in different magazines.
Until it will be tested on humans and then approved to treat humans it will take long long time. (my private opinion)
James
Title: Re: Very new study: Stem cells succeeds 100 % to treat peyronie's disease in rats
Post by: nemo on January 31, 2012, 10:52:08 PM
I do believe that's the ultimate endgame of Peyronie's research and treatment.  I just hope this godsend will come while we're still young enough to use it! 

nemo
Title: Re: Adult stem cell injections for Peyronie's
Post by: mariobros on February 06, 2012, 06:08:27 AM
Quote from: fubar on January 25, 2012, 02:26:35 PM
UK

Agreed not an awesome post.However it is true that treatment with stem cells with old scar tissue can and does become cancerous.I found this information on you tube, some seminar on stem cell treatment at a university.

They found stem cell treatment more effective with new wounds compared to old wounds.With the old they found that they could become cancerous with hair and bone,  and tumors growing .

I am sure that anyone of us could find this evidenced if one was inclined to do so.It would be reckless for one not to mention that this is a risk in stem
cell treatment.I do agree that post was vague and came across as an opinoin.

Fubar


I believe this generally applies more to embryonic stem cells than adipose derived which is what this procedure is. As embryonic stem cells are true "original cells" from another person they have virtually unlimited growth potential and can form literally any type of bodily tissue, thus they can have somewhat more volatile effects when transplanted into the human body.

Adipose stem cells as i understand are only capable of forming a select number types of tissues (smooth muscle, cartilage, bone etc) not fully formed eyeballs and the like you may have read about in "stems cells gone bad" stories, and as they come from the persons own body they have no risk of rejection and seem to have more predictable outcomes.
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on February 10, 2012, 05:17:54 PM
Just wanted to post the quick update, I just received my 6 month follow up call to see how I was doing, and to also let me know they have changed the proceedure for the stem cell treatment they are doing which the nurse said Dr Landers is exicted for and believes will help more than what they were doing when I had my treatment. I'm suppose to hear from Dr. Landers about the details of the improved proceedure and will post the info here. Other than that my status is the larger of the first two original lumps stills seems to be gone and the one I developed on the opposite side has been the same since it appeared. The nurse didn't have all the details about the new proceedure but mentioned it had something to do with emzymes that are used in conjunction with the stem cell proceedure to increase results. But again I will post more once I hear from Dr. Landers.
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on February 10, 2012, 05:55:05 PM
Thanks Rd

I have been wondering why we do not hear from other guys that have been to califonia stem cell for treatment.When i had called them they told me that they had been treating guys with Peyronie's. I think im going to send them a letter.Maybe they will pass our forum on to the patients.

It would be interesting to hear from others about their experience with stem cell treatment.It seems that some athletes are having some type of stem cell treatment for injures these days.

As time goes by i think more and more about having this treatment.RD you have not mentioned any adverse side effects that definitely is a plus! Disappearance of a lump does not sound bad eighter.


This new treatment sounds interesting cant wait to here more.


Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on February 10, 2012, 06:01:19 PM
I know when I went they asked me if I would be willing to talk to others about my treatment and I marked the box that said yes. So I don't know if others feel the same way about sharing their experience. Would be nice to hear from others. I am anxious to hear about the updated proceedure as I was already considering a follow up. I think I mentioned before but I had no pain or discomfort from the proceedure except for the prick on the needle with the numbing agent after that I actually felt like I did pre peyronies for the first two weeks or so. I did have some bruising and swelling or fluid which looked like swelling for the first week or two but felt no pain.
Title: Re: Adult stem cell injections for Peyronie's
Post by: Pat_Hos on February 11, 2012, 11:59:54 AM

Great to hear the doctor's are encouraged enough to refine the treatment.  I am most interested in this stem cell procedure as the Pentox really hasn't done much.  My fantasy is that stem cells will reset the clock back to the way things were before each of us got Peyronie's.  That may be overly optimistic.  Even a partial recovery of some of the lost length and girth would be amazing.  I have thought of trying the VED system but after reading how many hours a day it takes over so many months, I just don't see how that kind of time is possible.  I tried the Fastsize devise for over a year, and ended up smaller and with less elasticity than when I started after spending so much time in that contraption.  I will look into the VED further if it can reverse some of the lost elasticity from all the stretching.  First I need to know where to purchase the most effective VED system, which will not cause damage like the streching did.
Title: Re: Adult stem cell injections for Peyronie's
Post by: james1947 on February 11, 2012, 04:03:14 PM
Pat_Hos
VED is not hours daily as the Fastsize device. Is 15 to 30 minutes, one or two times per day.
I am proposing you to read the protocols for VED on "Vacuum Erection Devices (VEDs) for Peyronie's Diseases".
Same place you will find the different kind of VED's, prices and sources.
James
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: james1947 on February 14, 2012, 05:44:34 PM
I just come across the article bellow published at February 14, 2012:
Stem cells could potentially fix 'broken hearts'
They used stem cells to regrow damaged heart muscle and reduce the scar tissue.
Is very encouraging even they are stating that is phase 1 study. If applicable to heart scar tissues and regrowing heart muscles it should work for Peyronie's also.
As George stated:
Quotethis may well be the future of medicine when it comes to treating degenerative diseases.
James
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: George999 on February 14, 2012, 08:45:04 PM
It should be noted that at this point the FDA is rather hostile toward stem cell practitioners as they view the approach to be extremely experimental and they believe that charlatans are using stem cell scams to steal money from unsuspecting patients.  This might make such treatment difficult to come by and, perhaps risky.  I would ONLY have this sort of thing done at a major research center, not by someone who might turn out to be, indeed, a snake oil peddler.  - George
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: George999 on February 18, 2012, 12:38:06 AM
http://www.voanews.com/english/news/health/Scientists-Regrow-Tissue-Killed-During-Heart-Attack-139531913.html (http://www.voanews.com/english/news/health/Scientists-Regrow-Tissue-Killed-During-Heart-Attack-139531913.html)

If they can do it with hearts, they should be able to do it with TAs.  - George
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: restore on February 18, 2012, 08:13:01 AM
The future looks promising.  Too bad it's the future, and not the present.  If this takes ten years to reach us, then I'll get my penis back when I'm 60. 

Never thought sex at 60 would be better than at 50, but I'm no longer in a depression knowing things will get better through medical science.
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: james1947 on February 18, 2012, 07:31:53 PM
Restore
I appreciate your optimism, but I am in depression. Now 64, in 10 years 74. Who knows where I will be by then!
And also waiting 10 years is a very long time to wait.
James
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: rd on February 20, 2012, 08:52:27 AM
I dunno if I would estimate it being 10 years off. I had stem cell injections as most people know already on this forum. The larger of the two lumps has gone away. I still have deformity from the remaining lump and also developed a another small lump on the opposite side that causes some discomfort but no deformity. I am also considering going back for another treatment but waiting the 9 months recommended by the Dr before having a follow up proceedure done.
Title: Re: Stem Cell injection as possible peyronie's cure ???
Post by: james1947 on February 20, 2012, 09:57:18 AM
rd
Thanks for reminding me. I have read all your posts and I was very encouraged by your progress and same time appreciate your braveness to try it even now one on the forum don't try it before you.
It just sometime I get pessimistic (for a short time usually). 
James
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on February 24, 2012, 04:58:48 PM
Just got a update, the refined proceedure is for ED not for Peyronies - "the change in protocol is mostly for Erectile Dysfunction patients. It involves the use of PRP Platelet Rich Plasma with the stem cells."
Title: Re: Adult stem cell injections for Peyronie's
Post by: james1947 on February 24, 2012, 05:20:14 PM
rd
Thanks again for your updates. They are allways encouraging and useful, I am shore not just for me.
James
Title: Re: Very new study: Stem cells succeeds 100 % to treat peyronie's disease in rats
Post by: james1947 on March 01, 2012, 05:17:38 PM
Nemo
Read late you answer. Very funny!!!
Of course we will be still young enough (I am 64) if we will be still in this world.
James
Title: Re: Stem Cells and Peyronie's treatment
Post by: james1947 on March 01, 2012, 10:31:32 PM
For some reason things are going slowly in this subject.
On November 10, 2009 George topic "Treatments on the Horizon ..."
QuoteScientists Grow New Penile Tissue in the Lab
was a very promissing research but we don't see any update until today of any progress.
On November 04, 2011 George added a new research
QuoteTissue created in a laboratory has been used to completely replace the erectile tissue of the penis in animals.
not similar but very close.
Your link
Quotehttp://www.huffingtonpost.com/2012/01/23/stem-cells_n_1224764.html
regarding the new research is also not similar but not far.
Have many other researches regarding stem cell therapies for other things than Peyronie's but as I understand can be used also for Peyronie's, I am attaching one.
It seems that have some researches by some researchers that maybe knows or maybe not about each other.
In parallel have some clinics that already offers stem cell therapies. rd, member of our forum tried out stem cell injections with positive results.
My private opinion, things are going slowly in the subject even is a very promising approach because the uro's don't see big money from it and maybe it will replace many of the surgeries and therapies done today that are making big money.
James
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on March 27, 2012, 07:16:01 PM
Tomorrow i have an appointment with Dr. Landers from the California stem cell treatment center.
I know this is short notice but the appointment has been moved not by my choice.I would like to know if anyone has something they would like me to ask the doctor?

I have the opportunity  this year and the funds to have the procedure. So i would be able to travel in May or whenever my leave and their scheduling permits.Naturally i will investigate more before i make a final decision .To me there are still many what ifs and we all know things can go wrong.

This procedure is not fda approved .I have yet to hear or find testimonial that one has been cured.They advertise this as patient funded research and claim the procedure to be lawful on their site.


Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: james1947 on March 27, 2012, 11:51:45 PM
Fubar

It seems that rd had good results.
From what I read on the forum some people are concerned regarding cancer with this treatment.
Other opinions are that it is other kind of cell therapy that may have cancer problems.
I think you should ask him this question. It may clear the point for all of us.

James
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on March 28, 2012, 03:16:43 AM
James

This is the number one question on my list. Cancer has been a major concern from the beginning for me after reading and watching lectures on stem cell  .I learned that cancer is a possible outcome resulting in hair, bone or tumor becoming abnormalities in the healthy tissue.


Knowing cancer spreads quickly and is hard to treat ,often renders one dead more times than not. The possibility that Cancer is a threat , warrants more investigation before treatment.


Fubar


Title: Re: Adult stem cell injections for Peyronie's
Post by: GS on March 28, 2012, 08:53:13 AM
Obviously rd is a brave soul for going through with the stem cells.  But Fubar, you are also a brave man to consider it.

I wish both of you the best and I'm sure you will both keep us all updated.

GS
Title: Re: Adult stem cell injections for Peyronie's
Post by: fubar on March 28, 2012, 11:29:28 AM
Gs

You know what they say there is a fine line between bravery and stupidity.

Fubar
Title: Re: Adult stem cell injections for Peyronie's
Post by: rd on March 28, 2012, 02:01:00 PM
While doing my research on this, the way I understood it was that the adult stem cells they have never seen a case of cancer yet, but with the embronic stem cells  they at times seen it result in cancer.
Title: Re: Adult stem cell injections for Peyronie's
Post by: james1947 on March 28, 2012, 09:23:27 PM
I agree with fubar and also with gs.
What I am thinking that all of us with this disease are walking sometime on this thin line. Maybe we all are adventurers, or maybe pioneers?
In any case we are Guinean pigs in many of the doctors trials. I hear from a very high level doctor/professor that they are doing trial and error until finding a solution.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: fubar on April 03, 2012, 03:03:21 PM
Wow took me some time to get here.I see they are combining topics that are the same.Funny though i started the topic first and now part of someone elses.Hmmmm anyway i spoke to Dr.landers last wednesday.He was generouse with his time and had no problem with listenimg and let me exspress my thoughts on the stem cell treatment.

Seems that there are is much to learn about the stem cell therapy and treatment.Dr. landers has been a urologist for over twenty years and has been treating stem cell for a few.He seemed very excited about what he is doing and the progress they are making at the treatment center.They have treated over 150 patients looking for relif from what ever they are suffering.Califonia stem cell center has had progres with some treatments that others in the world have had no such luck.The center is staffed with other doctors and all treatment and harvisting of the stem cells is done on the premises.They lipo suck from the belly button fat then harvest the stem cells with a machine they use.Inspect the cells to see how many and the health of them.While they are harvesting you sit in a room for a few hours watching telivision or reading.He said after the injections you are free to leave .

Asked him if there were any cancer issuses he said no there are none with audult stem cell.How many treated for Peyronie's he said 2 or three.I believe in reality probably only one that would be rd our fearless hero.There was another guy he spoke of outside the U.S. that after speaking to a patient changed his mind although he had progress was not cured.The there was a guy who had a graft incision and his graft patch had turned hard as stone.

Dr. Landers told me he did not think it was a cure yet that maybe some one will come up with the wright combinations of stem cells one day.He said that he really does not know what treatment is going to work but that they are trying different things with procedures all the time.This is something that warmed my heart that finally a Doctor admitting he was on his own with this trying his owm way and get this that Peyronie's was a huge problem.Now when have you heared a Urologist say that?


He mentioned that the mostley treat bone,  musle, and has treated a guy with dupytrens.I am interested to see how dupytrens procedure results.He asked me if i had any fat on me.I said barely that i lost 21 lbs in the last month an 50 the year before.Still he assured me this was not a problem.He said that before and after the procedure not to take asprin that this cause the stem cells not to be able to communicate.You know when when injured we all have are own stem cells that COME to THE RESCUE!
So to new Peyronie's suffers DO NOT TAKE ASPRIN!This is my personal opion that when first injured having the stem cell procedure will have the best results.When i first found this center i was in the acute stage i should have jumped for ghe treatment then.Truth i have no resevations about having stem cell treatmwnt now.I told Dr. Landers i had brought the the topic(Adult stem cell injections for peyronies. That it seemed it was not a hot topic and few have intrest.I did however say that a couple seemed interested an basically started the same topic using different words.Bassically same old problem people do not look over topics or read to see if it has been mentioned.

I would like to the James1947 for his efforts consolidating  and being a great moderator! It is good to have you in this seat you seem to be working very hard in making the forum a better and easier to navigate.

Well if i can think of anything else i will be sure to post sorry for the wait.Oh yeah rd they have dropped the pricw on the treatmwnt to three or four thousand he was not sure.They have been trying to cut the cost.Dr. Landers stating that the reason why is that he feels the cost is steep without the patient knowing he will have positive results.Look guys we all have been saying wish someone will take interest in Peyronie's. Well we have someone and he is excited about what he is doing more so than any other time in his career.He thanked me for getting the word out because they need patients.I would think seriously about havimg this done if you are young and in the early stages of peyronies.Sorry if there is misspellings or i have been long winded.Thank you for listening.

Fubar

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on April 03, 2012, 07:15:22 PM
Fubar

Thank you  for the update. It is long but worth reading. Is indeed encouraging that a doctor want to help Peyronie's sufferers and if I was not so far I was giving a try. Also the price reduction is encouraging.

rd is our real hero hear and I wish this treatment will help and help all the others that will follow.

My apology to you not keeping your original topic name even you was the first with the stem cells post. When I am merging topics, I try to give names that reflects as much possible all the included topics.
One of the problems is that sometime people (also myself) are not trying the "search" on the top of each window of the forum and try to see if have some similar or close topic before opening new one.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: fubar on April 03, 2012, 11:54:42 PM
James1947

True we need more suffers to go and have this treatment. Even if it is trial and error that is the way things are worked out before finding a protocol that succeeds.The center has had progress so i do not think that it is failure.When you have injected the plaques of a patient and they disappear over many months.This is a success! Having the damaged removed by the stem cells and then replicating the healthy (TA) cells must be pretty tricky. When they do that then we will be cured and this will only be a bad memory for those that have this miracle happen for them.

Fubar
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Luciano on April 04, 2012, 01:03:15 AM
@fubar & james
I agree that it would be great to have lots of people try this and be able to find a cure with stem cells.
The price is not what matters... even if its $20.000, its the price of a car. If I would get rid of Peyronies Disease i would ride a bike for the rest of my life.
I think though the problem is different.
There are too little serious institutes offering this kind of treatment. Too little experienced docs that would apply it, too little information on the risks (cancer &c o), etc.. etc..
So if I agree this is great outlook for younger patients, I am not so euphoric for myself because:
I am not a heroe
I dont want to be a guinea pig
and I am to old - as I only have a couple of years left to use my thing, I cant wait for 10 years for a stem cell therapy to be well adjusted for peyronies.
(thats why I am seriously considering surgery)

But I do find it great that some of us seriously look into it. It gives us hope, hope for the group, so that maybe the younger ones among us can see a light on the horizon.

Luc
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on April 04, 2012, 12:31:09 PM
Quote from: fubar on April 03, 2012, 03:03:21 PM
Wow took me some time to get here.I see they are combining topics that are the same.Funny though i started the topic first and now part of someone elses.Hmmmm anyway i spoke to Dr.landers last wednesday.He was generouse with his time and had no problem with listenimg and let me exspress my thoughts on the stem cell treatment.

Seems that there are is much to learn about the stem cell therapy and treatment.Dr. landers has been a urologist for over twenty years and has been treating stem cell for a few.He seemed very excited about what he is doing and the progress they are making at the treatment center.They have treated over 150 patients looking for relif from what ever they are suffering.Califonia stem cell center has had progres with some treatments that others in the world have had no such luck.The center is staffed with other doctors and all treatment and harvisting of the stem cells is done on the premises.They lipo suck from the belly button fat then harvest the stem cells with a machine they use.Inspect the cells to see how many and the health of them.While they are harvesting you sit in a room for a few hours watching telivision or reading.He said after the injections you are free to leave .

Asked him if there were any cancer issuses he said no there are none with audult stem cell.How many treated for Peyronie's he said 2 or three.I believe in reality probably only one that would be rd our fearless hero.There was another guy he spoke of outside the U.S. that after speaking to a patient changed his mind although he had progress was not cured.The there was a guy who had a graft incision and his graft patch had turned hard as stone.

Dr. Landers told me he did not think it was a cure yet that maybe some one will come up with the wright combinations of stem cells one day.He said that he really does not know what treatment is going to work but that they are trying different things with procedures all the time.This is something that warmed my heart that finally a Doctor admitting he was on his own with this trying his owm way and get this that Peyronie's was a huge problem.Now when have you heared a Urologist say that?


He mentioned that the mostley treat bone,  musle, and has treated a guy with dupytrens.I am interested to see how dupytrens procedure results.He asked me if i had any fat on me.I said barely that i lost 21 lbs in the last month an 50 the year before.Still he assured me this was not a problem.He said that before and after the procedure not to take asprin that this cause the stem cells not to be able to communicate.You know when when injured we all have are own stem cells that COME to THE RESCUE!
So to new Peyronie's suffers DO NOT TAKE ASPRIN!This is my personal opion that when first injured having the stem cell procedure will have the best results.When i first found this center i was in the acute stage i should have jumped for ghe treatment then.Truth i have no resevations about having stem cell treatmwnt now.I told Dr. Landers i had brought the the topic(Adult stem cell injections for peyronies. That it seemed it was not a hot topic and few have intrest.I did however say that a couple seemed interested an basically started the same topic using different words.Bassically same old problem people do not look over topics or read to see if it has been mentioned.

I would like to the James1947 for his efforts consolidating  and being a great moderator! It is good to have you in this seat you seem to be working very hard in making the forum a better and easier to navigate.

Well if i can think of anything else i will be sure to post sorry for the wait.Oh yeah rd they have dropped the pricw on the treatmwnt to three or four thousand he was not sure.They have been trying to cut the cost.Dr. Landers stating that the reason why is that he feels the cost is steep without the patient knowing he will have positive results.Look guys we all have been saying wish someone will take interest in Peyronie's. Well we have someone and he is excited about what he is doing more so than any other time in his career.He thanked me for getting the word out because they need patients.I would think seriously about havimg this done if you are young and in the early stages of peyronies.Sorry if there is misspellings or i have been long winded.Thank you for listening.

Fubar



This was pretty much my experience speaking with Dr. Landers and with my proceedure. He was open about not knowing all there is to know how the stems cells work and that they are still learning. He seemed to be refreshing and excited about finding a solution to this condition. The proceedure was like as described I went in had my concelltation and then the proceedure. They did how ever have to harvest the fat from my lower back as I am very lean unusually lean then most being in the single digits for body fat. After that I sat in another room and watched tv while they processed the fat/stem cells. Once that was done I went back in to the harvesting room and had them injected in around and under the plaque. The only pain I had was from the first shot to numb the area and it wasn't that bad. Right around noon Dr. Landers dropped me back off at the hotel. I was hungy so I actually ended up walking about half mile to a restuarant to get some food then back to my hotel. Also that night I woke up with a errection which didn't hurt either. The only discomfort I had was the lipo area it bothered me for a few month but I expected that from what I was told and new of others who had just lipo. Also I had the one lump disapear and the remaining of the original two lumps on the right side seems to have shrank and become squishy as of today. I still have a dent or more hour glassing at this time but I figured I would unless the lump completely resolves. I did develope another small lump on the opposite side that just appeared one day and hasn't changed any that I can tell. It doesn't cause any dents or hourglassing or aything that i can tell but just a little discomfort. It is refreshing when talking to Dr Landers and seeing his excitment about doing something about this condition. They have also contacted me when they have had a potential patient who wants to talk to someone about there experience and asked me if it would be ok if they could email or they could give my contact info to the interested person. So far I have talked to one person via email to share my experience thus far. I am also considering a follow up proceedure because of the results I have seen. I am waiting till may which will have been 9 months which Dr. Landers sugguested I wait before having a second proceedure done.

Some of this is repeat info but I figured I would share it again incase some had read it in my previous posts.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: fubar on April 05, 2012, 05:58:41 PM
You know something crazy has just occurred to me.What if the mature scar tissue was reinjured and then stem cells injected into the scar tissue.Could this inturn create a better bed for the stem cells to replicate and mend the rough surface more to what it once was?Just a thought knowing there is a better chance of repair with a new wound.I have had Peyronie's  atleast 24 months or longer.

Fubar
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on April 05, 2012, 06:29:41 PM
Fubar

In my private opinion it is CRAZY because you don't know what will be the result of the reinjury.
Also it may come out not exactly in the same place and then you will have two instead of one!!!

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: fubar on April 05, 2012, 09:04:09 PM
Yes it may be crazy and sound risky but there are ways to agrivate the scar.Maybe pin point lazer treatment or botox im sure there are other ways .Does not mean it wont work.You want stem cell to replicate the (ta) not a wound that is a mass of plauqe or calcification.A mature wound has less of a chance to recover and heal.

I did not say i was going to have this done.I will ask doctor Landers thoughts on it Though and i would make a decision based on the all information Pros or cons.Nobody has really broken the ice on Peyronie's. There will be many procedures attempted and protocols changed to find any cure with this.But i think it will defnately come from the cellular level.


Fubar
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Luciano on April 23, 2012, 02:26:19 PM
talking about stem cells, I read in a french newspaper that Wayne Hellstrom (tulane university, new orleans) did some tests on rats...
incision on penis so the devellop curvature, then doing surgery using a special graft (sis i think), but putting stem cells harvested from the fatty tissues on the graft .
8 weeks after surgery, the rats had not only a stronger penis, but better irrigation and better erection and more girth.

The paper (Le Point) writes they are going to do more tests on monkeys.
Strange I never heard of a study going in that direction.
Luc

Edit:
Found the exact same article in english:
http://news.sciencemag.org/sciencenow/2012/01/stem-cells-build-a-better-rat-pe.html

and the abstract of the study by Hellstrom:
Adipose tissue-derived stem cell-seeded small intestinal submucosa for tunica albuginea grafting and reconstruction
Abstract:
http://www.pnas.org/content/109/6/2090

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on April 23, 2012, 07:40:45 PM
Luciano

Thanks for the information.

It is encouraging that more and more researches are done in this direction.
It may be the real future answer for Peyronie's an for many other diseases.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on June 08, 2012, 03:19:09 AM
rd

How is your progress as for today compared to when you started your treatment?
You are continuing with the second procedure?

Maybe by the end your treatment is the future for Peyronies.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on June 08, 2012, 04:12:28 PM
Not much to report since my last post. I am saving up for a second proceedure and also talked to someone on the phone who said they were having it done in two weeks so I believe that might have been this week or next. They said they would keep me up to date on there progress as well. I'm not sure I will be able to have the second proceedure before the year is over as I have had some expenses come up(dog blew out his ACL) but I am putting a little bit away each month towards a follow up proceedure. Wish I had more to report. I will post any info from the person I spoke to on the phone results wise as he reports them to me as well. So that way we will have two accounts of how the proceedure did for two different individuals. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on June 08, 2012, 06:52:43 PM
rd

Thanks for the information, crossing you fingers to have enough for the followup process as soon as possible.

Sorry to hear about your dog, I love them, my mother was allways saying they are better than humans. By the way, what is ACL? I am not so good in English, so I don't know.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on June 09, 2012, 07:43:51 AM
Yeah he has bad luck with his rear legs already having torn his other acl years ago and having surgery for that as well. Oh and ACL stands for anterior cruciate ligament(http://en.wikipedia.org/wiki/Anterior_cruciate_ligament (http://en.wikipedia.org/wiki/Anterior_cruciate_ligament)).
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on June 20, 2012, 06:31:47 AM
Just wanted to give a update. I have been leaving the plaque alone for a month at a time then checking it to see if there were any changes. Well this morning I checked the remaining lump that was treated and it has become really soft and squishy. Up until this time it was a hard rice shaped lump running side ways on my shaft. This is what the other one appeared to do before it disappeared. So I am hoping this does the same. I still have the hour glass deformity and a plaque on the other side of my shaft but I don't expect the hour glass deformity to go away until I can't feel the lump even though it is very soft and has no hardness at all. It's been about 10 months since I had the treatment and like I said before I am saving up little by little for a follow up as well. I am also going to email Dr landers and let him know that I am still interested in a follow up but am still having changes so I am going to wait one because of money and two to see if things continue to change. I also found that laying on a heating pad seem to help any pain or discomfort I have. I went out to and just bought a cheap CVS heating pad and put it on the second highest level and lay on that when I go to sleep. At some point while sleeping I end up rolling off of it and or knocking it off the bed but the heat seems to help a lot with the pain and discomfort even the short time I lay on it before falling asleep.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on June 20, 2012, 12:15:46 PM
rd

Thanks for the update. Is very encouraging!
I know that in Peyronies everything is very personal and what is working for one may not work for an other, but your results are very promising.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: anonimo on July 05, 2012, 05:00:44 PM
Hi to all,

i'm very interested into this thread, let me tell you why

i'm in treatment for peyronie, but it is a strange peyronie. i've pain, curvature, inflammation, but - standing to 2 ecodoppler that i ve done in the last 6 month - i've no plaque! from ultrasound analysis seems that i ve "only" fibrosis area  (i dont know how to explain, my english is very bad). I dont know if on this forum there is someone without no placque, maybe i ve read one in the past. but no others...

anyway, during these 2 years, i ve read a lot to understand what i have and i ve found casually another autoimmune disease that can hit penis and that does not develop placque, but only fibrosis area (on the tunica too, but either on glans). It is called lichen sclerosus, and it is a very similar for some things to peyronie... (you can google to find some information... )

so, today i ve found this topic and i ve read about stem cells. i remember a similar thing.......for lichen sclerosus

http://lichensclerosus.org/italian-stem-cell-treatment/ (http://lichensclerosus.org/italian-stem-cell-treatment/)

I know that in Italy (Genova) dr. Casabona is using with success stem cells for lichen sclerosus (for women, but men too..). It is an experimental methods, but seems it works becuase i ve read that comes people from other countries...

Now. I want to be clear, i dont know if it is the same thing, but in my opinion the effects of "dead-tissue" are very very similar (i ve no placque!) so im going to call the dr. casabona next month to talk about my situation and to listen what he think about it. The treatment with stem cell is the same..

Genova is near to my town, i can not loose this opportunity... i want to know if you agree with me about what i ve written

(again, excuse me for my english..)

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: fubar on July 05, 2012, 06:40:43 PM
Sounds interesting to me! Please keep us informed and what you learn about the process!
Thank you for posting i will read up on this tonight!

FUBAR
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on July 07, 2012, 09:40:25 AM
One question for rd and others:

Is a stem cell injection the same of a Platelet Rich Plasma (PRP) injection?

If not, what's exactly a Stem cell Injection? where do they take the stem cells? thanks
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on July 07, 2012, 12:11:57 PM
yyy,

A stem cell injection is different then a PRP injection. I know Dr Landers is using a combination of the two for ED. But he doesn't do that for peryronies only the stem cell injection. A stem cell injection is the following. They harvest fat from your mid section which contains adult stem cells. Once harvested they run it through a machine/process that extracts, counts, and determines the health of the stem cells which are then injected into the lumps or plaques whatever you refer to them as.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on July 08, 2012, 09:11:37 AM
rd,

Thank you for your quick reply.

According to your personal experience, would you advise this kind of injection?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on July 23, 2012, 03:09:21 AM
I am posting a link to an article related to adult stem cell therapy.
It was done for ALS patients, not for Peyronies but the most important point is that phase I & II main issue was the safety of the treatment.
It may be interesting especially for rd because he is doing stem cell therapy for Peyronies and to anybody else intending to do such treatment.

http://health.yahoo.net/news/s/nm/israel-adult-stem-cell-trials-hope-for-als-patients

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on July 23, 2012, 04:50:42 PM
Yeah I have had no ill effects from the treatment almost a year ago. In fact I had one lump go away, and I told fubar just recently in a pm that My remaining treated lump is really hard to find now. I believe its almost gone only with a trace amount of it left. I have to search around for it to find the little bit thats left. I also think the one I developed on the left side of my shaft has shrunk as well. I still have hour glassing but until the lump is fully gone I suspect the hour glassing to stay. But I am really encouraged in a years time to have had the progress I have had thus far. Also with the stem cell therapy I have kept a clean diet low in refined sugars and very little processed food. Basically just meats, nuts, berries, fruits and veggies. I also added more cardio to my workouts as before this I was primarly doing weight lifting. I haven't once been sick in over a years time since cleaning my diet even when around sick coughing sneezing clients at my office. I am going to continue to monitor my progress and report back.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on July 23, 2012, 05:09:41 PM
rd

Your treatment is encouraging.
I just hope that in the future the treatment will be available in other parts of the world and will be covered by insurance.
I am sure many people that are reading your posts was doing the treatment if it was cheapper or covered by insurance.
What about ED? You had ED before the treatment?
Did you lost length and girth to the Peyronies? If yes, the treatment helped with this subject?

What is encouraging in the article I have posted the link that no side effects were monitored.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on July 23, 2012, 07:23:13 PM
James, I had no ed at all with my peyronies, no curve either just lumps pain and dents(hour glassing). No loss in length either. Hopefully if this is the answer it will get cheaper better and more available and covered by insurance.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on July 23, 2012, 07:27:42 PM
rd

Thanks for the replay.
I was blessed with all the Peyronies effects.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on July 26, 2012, 10:49:23 PM
It seems that stem cell therapy is taking off more fast in the last period, with many success stories regarding organs regeneration.

http://www.foxnews.com/health/2012/07/26/first-ever-child-recipient-novel-stem-cell-trachea-recovering-well/

James
Title: Anyone Tried Stem Cells for Erectile Dysfunction?
Post by: koolx on August 06, 2012, 10:14:03 PM
i'm tnhking about getting stem cell therapy for my condition of ED. has anyone improved their erectile dysfunciton with stem cells?
Title: Re: Anyone Tried Stem Cells for Erectile Dysfunction?
Post by: LWillisjr on August 06, 2012, 10:21:05 PM
ED can be caused by a number of factors. The process of obtaining an erection is quite complex. I would think you would need to know exactly what the issue or malfunction is causing your ED problem before you could treat it it with stem cells.
Title: Re: Anyone Tried Stem Cells for Erectile Dysfunction?
Post by: koolx on August 06, 2012, 11:39:10 PM
Quote from: lwillisjr on August 06, 2012, 10:21:05 PM
ED can be caused by a number of factors. The process of obtaining an erection is quite complex. I would think you would need to know exactly what the issue or malfunction is causing your ED problem before you could treat it it with stem cells.

well, my ED was caused by a medication i took 16 yrs ago. it gave my body a lot of pain, especially in my groin area. it caused so much damage that the base of my erection were constricted.. the constriction is gone.. but the after effects are still there. i've been to many urols and they all cant help.

thats why i'm seeking stem cell therapy as help. anyone here had it done?
Title: Re: Anyone Tried Stem Cells for Erectile Dysfunction?
Post by: fubar on August 07, 2012, 12:52:04 AM
When i spoke with a Doctor who treats patients with stem cell. He told me there has not been a successful treatment for ED yet. I know this is something you do not want to here but this is what i was told. That is not to say it wont happen but the fact is that stem cells used for penile issues is new and in the early stage of research. Most treatment probably also patient funded.

Fubar
Title: Re: Anyone Tried Stem Cells for Erectile Dysfunction?
Post by: koolx on August 07, 2012, 06:39:39 PM
Quote from: fubar on August 07, 2012, 12:52:04 AM
When i spoke with a Doctor who treats patients with stem cell. He told me there has not been a successful treatment for ED yet. I know this is something you do not want to here but this is what i was told. That is not to say it wont happen but the fact is that stem cells used for penile issues is new and in the early stage of research. Most treatment probably also patient funded.

but why then have there been so much research done with proof that verifies that stem cells can heal ED? the internet is abuzz with proof on this.

can you provide links that support what youre saying? i've never come across info that suggests what youre saying is accurate.. i'm not saying youre lying.. but i'd like to read up on solid research on this.please provide links.. thanks.
Title: Re: Anyone Tried Stem Cells for Erectile Dysfunction?
Post by: james1947 on August 07, 2012, 06:57:24 PM
koolx

I will second fubar post word by word.
Regarding
Quotethe internet is abuzz with proof on this
try to find a serious trial regarding "stem cell therapy". My self didn't find. Some people make good money from other people desperation.
I am proposing you also read "Developmental Drugs & Treatments > Stem Cells & Adult stem cell injections for Peyronies.
You may PM rd and ask him the question, he is doing stem cell therapy and maybe he knows the answer to your question.

James
Title: Re: Anyone Tried Stem Cells for Erectile Dysfunction?
Post by: koolx on August 09, 2012, 12:43:00 AM
Quote from: james1947 on August 07, 2012, 06:57:24 PM
koolx

I will second fubar post word by word.
Regarding
Quotethe internet is abuzz with proof on this
try to find a serious trial regarding "stem cell therapy". My self didn't find. Some people make good money from other people desperation.
I am proposing you also read "Developmental Drugs & Treatments > Stem Cells & Adult stem cell injections for Peyronies.
You may PM rd and ask him the question, he is doing stem cell therapy and maybe he knows the answer to your question.

James

yeah i'll pm 'rd'. thanks.

Title: Re: Anyone Tried Stem Cells for Erectile Dysfunction?
Post by: fubar on August 11, 2012, 04:32:28 PM
Koolx

I sent you a pm i never mentioned a link. I sent you the  doctors name and his center. So do a google and get his number and give him a call. I asked him about Ed because i have suffered from that as well. I know there are sites claiming that stem cells work for Ed but it just is not so. It would be all over the news millions of grand fathers standing in lines.  It would just be Epic!

Hope this helps

Fubar
Title: Re: Anyone Tried Stem Cells for Erectile Dysfunction?
Post by: james1947 on August 11, 2012, 05:04:52 PM
Some millions + 1 (I am also grand father already)
;D ;D ;D
James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on August 13, 2012, 08:37:48 PM
Just another update, its been a year since I had the stem cell injections, my last post I reported that I almost couldn't find my lumps. Well as of today I can't find them at all. I still have hour glassing but it seems to be getting less and less. The progress is slow and I would love it to be faster but it appears to be gaining thickness where the indent is of the hour glassing or filling in. I noticed even though the lumps can't be felt that it still gets sore when I poke and prode at it. I believe I may still have some inflammation left. I will give another update in about a month. I have also been eating only meats fruits veggies nuts and berries. I stay away from dairy breads and pastas. Every great once in a while I treat my self but I make it a very rare treat. Not sure if this has contributed to my improvements or not but wanted to mention it as well.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: fubar on August 14, 2012, 12:07:23 AM
Rd

I think feeling a little inflammation in the area is a good sign. Letting you know your body is still at work, doing repair.

Good to hear you are doing well and your progress keeps us holding on. When thinking about it all hard to believe you stand alone in this treatment. You may have gone where no man has gone before having your own cells repair damage in your penis. On behalf of the forum and I  personally  applaud your courage. Though i would consider this the appropriate course. Many still feel xialflex, Pentox, coq -10 and various other remedies less invasive.

I suppose someone above our existence will sort this one out. Still i feel we are getting somewhere with all of this.I wish you the best my friend and feel inspired to hold on to hope with your report.

Fubar
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on August 14, 2012, 07:20:46 PM
I will second fubar on every word and thank you for your constant updates.
Your courage is remarkable and your results as well.
I wish I was living in a place that this therapy is available.

James

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on August 21, 2012, 06:35:43 PM
Hi guys

I have an important update for me and maybe for you as well.

At the end of September I will do some PRP injections in my fibrotic plaque here in Italy. They will be totally free as covered by national health service.
The doctor said that PRP injections have more or less the same (good) effectiveness than the Stem cells ones, but they are much less invasive as the needle is much smaller.
About results, he used this technique with some patients affected by peyronies and he had improvements, sometimes very good sometimes not, but always little improvements; he added the procedure has no side effects.
I remember I do not have peyronie disease, only a fibrotic plaque due to a surgery; I PERSONALLY suppose that people with peyronies could have a bigger risk on having (all kind of) injections, but who really knows..this time Im pretty confident.

TO JAMES: I asked about foreign patients, he told me that EU citizens can be covered and have it for free but EXTRA-UE have to pay 400euros

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on August 21, 2012, 07:01:45 PM
yyy

Thank you for the updates, also regarding the injections and also regarding the coverage.
I am EU citizen but my problem is that with my severe ED I don't know if I have patience to wait more.
I have two questions:
1. What is PRP?
2. How many injections you will get?

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on August 21, 2012, 07:32:44 PM
PRP is platelet rich plasma, they take and treat your own plasma and inject it into the plaque. It helps to regenerate new healthy cells
I will have one treatment (injections in several points), then we wait 3-4 months for the results and decide what to do
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Luciano on August 22, 2012, 02:12:45 AM
Quote from: yyy on August 21, 2012, 07:32:44 PM
PRP is platelet rich plasma, they take and treat your own plasma and inject it into the plaque. It helps to regenerate new healthy cells
I will have one treatment (injections in several points), then we wait 3-4 months for the results and decide what to do
Looking forward to your reports!!!
PRP injections a usually used to linder inflamation with tooth implants and for other surgery (like knees, tendons etc...)
I have read about it, there is very little though about them in relation with Peyronies Disease.
only thing I know for sure is, that it is not a fda approved treatment for Peyronies Disease.

the more than strange thing is, I found a patent application someone made for Peyronies Disease treatment:
Actually it is for injecting high pressure collagenase into the plaque.
but you can read in the explanations:
Quote[0060] In some embodiments, the cell matrix can include platelet rich plasma (PRP) or platelet poor plasma (PPP). PRP is blood plasma enriched with platelets. Through degranulation of the platelets, PRP can release different cytokines that can stimulate healing of soft tissue. Processes for PRP preparation include the collection of centrifugation of whole blood which separates PRP from platelet-poor plasma and red blood cells. In some cases, the adipose-derived stem cells are combined with PRP and injected into the area of the penile plaque following injection of the collagenase-containing composition for cell based therapy. The healing proteins in PRP are advantageous and can assist in making areas of the injected tissue "sticky" for the attraction and retention of the treatment cells. PRP also includes many regenerative proteins to hasten healing. The adhesive or retention function of PRP can prevent cells from migrating or being lost through vascular flow.

[0061] In some embodiments, the cell composition with adipose-derived stem cells includes platelet poor plasma (PPP). PPP is typically characterized by a very low number or platelets (<50000/uL) and a high concentration of fibrinogen. PPP can be prepared in a centrifugation process that separates it from PRP and red blood cells. PPP can provide an autologous scaffold-like material to keep injected cells local to penile plaque to improve the regenerative potential of the cells. PPP can be beneficial to tissue as well. The PPP can include a porous gelatinous material to keep cells local to the injection site and provide a therapeutic effect. PPP can allow the movement of cytokines and other signaling molecules in and out of the tissue for regenerative mechanisms local to the injection site.
(the patent application is here : http://www.faqs.org/patents/app/20120156178 )


Now my question: I have never heard of a patent on a treatment for a desease #?§% !!!

Luc
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: LMP on August 31, 2012, 12:19:09 PM
Quote from: yyy on August 21, 2012, 06:35:43 PM
Hi guys

I have an important update for me and maybe for you as well.

At the end of September I will do some PRP injections in my fibrotic plaque here in Italy. They will be totally free as covered by national health service.
The doctor said that PRP injections have more or less the same (good) effectiveness than the Stem cells ones, but they are much less invasive as the needle is much smaller.
About results, he used this technique with some patients affected by peyronies and he had improvements, sometimes very good sometimes not, but always little improvements; he added the procedure has no side effects.
I remember I do not have peyronie disease, only a fibrotic plaque due to a surgery; I PERSONALLY suppose that people with peyronies could have a bigger risk on having (all kind of) injections, but who really knows..this time Im pretty confident.

TO JAMES: I asked about foreign patients, he told me that EU citizens can be covered and have it for free but EXTRA-UE have to pay 400euros

Does anyone know if anything like this is available in the UK?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: nastyone on September 02, 2012, 12:42:15 PM
This area of study should me much more researched. I believe if there were more stem cell researchers working specifically on effective peyronies treatment, there would be major advances in the near future. What could be better than to grow healthy tissue back. I one of the young ones on this forum and this feels like a new hope. Even if i have to wait years. At this point, i definately dont want to do anything  irreversible, because you never know if a new type of effective treatment could be just a year or two around  the corner. I just wish more stem cell reasearchers were focused on use for peyronies.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on September 02, 2012, 07:21:31 PM
nastyone

It is not a research, it is just one forum member testimony, but I am proposing you to read rd (forum member) posts on the subject. It sounds promising. :)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: fubar on September 04, 2012, 01:32:21 AM
Nastyone

Though James is a good man he is spreading himself thin. I brought adult stem cells to treat Peyronie's and  regenerative medicine to the forum. Then he became a moderator and gave george999  who is the forums genius of vitamins and health my topic. However i started it and can answer your question being the one of two that can give you testimony. RD is the only other having the treatment not me

I do stay in touch with Rd and he with me. I spoke to the doctor of the treatment center and the treatment is totally patient  funded.  Rd will tell you the same. If the post still exist as it seems many being deleted by new moderators looking to be of importance.

Take a look for yourself do not ask for answers so much look for resolve. Call the stem cell center he is a good doctor. Be warned every procedure is tweaked because they are trying to find remedy. He was very truthful with me  do not have the answer yet.

RD has had positive changes then again so have i with out stem cell treatment. you should always research everything do not think we know answers?;We do not we are looking too. We support and give what works for us.
Some are knew with many answers but to be honest do not ask much better to use the search bar.

I could not find a post that was tagged by a moderator , punched in some words that i wrote and i was not disappointed.  Put a little work and i find my answer.

Fubar ( do not settle for quick answer!)

ps. when i talked to Dr. landers they knocked a couple bills off the treatment is about three thousand dollars now

Patient funded mind you! Just one mans testimony with hinge, bent loss of girth uselessly looking for resolve.


fubar
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: richard wheeler on September 04, 2012, 02:44:41 PM
I spoke to Dr Lander last week . he was nice and answered all my questions .i am on the fence about whether or not to pursue this. I am glad that you mentioned the cost being around 3 grand. He quoted me at the start 7 grand!!!!i told him i knew what rd was charged and he said he could probably knock it down to 6 grand! maybe Canadians have more money!!!lol.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: bummedout on September 04, 2012, 06:46:17 PM
I haven't really been keeping up on all the post for stem cells, but please be aware of scams.  There have recently been reports on 60 Minutes (a reporting program in the USA) about con artists that claim that stem cells are the cure all to any disease.  If it is legit than I wish you luck, but please be careful.

Here is the link:  Stem Cell Fraud: A 60 Minutes investigation - CBS News (http://www.cbsnews.com/8301-18560_162-57497588/stem-cell-fraud-a-60-minutes-investigation/?tag=currentVideoInfo;videoMetaInfo)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: LWillisjr on September 04, 2012, 08:24:15 PM
Quote from: fubar on September 04, 2012, 01:32:21 AM

If the post still exist as it seems many being deleted by new moderators looking to be of importance.


Fubar,
I don't want to get off topic here but need to make a point of clarification. None of the moderators here that I am aware of are deleting any posts. If a thread starts to go in the direction of a different topic, we may split the thread to keep the integrity of the first topic and start the second. But all the posts/threads should be intact.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Hawk on September 04, 2012, 10:03:09 PM
Quote from: fubar on September 04, 2012, 01:32:21 AM
....If the post still exist as it seems many being deleted by new moderators looking to be of importance.

fubar

Fubar,

You owe an apology to me and to every moderator on this forum.  I have poured my money and thousands of hours of blood, sweat, and tears into setting up the the best resource for men and their partners for Peyronies Disease on the internet.  It was and is based on giving a voice to all, including those that make ridiculous statements.  A good example is your statement and the statement you begged moderators to delete this week because it did not suit you.  THIS FORUM WAS FOUNDED EXPLICITLY TO PREVENT THE CENSORSHIP THAT HAPPENS ON DOCTOR RUN FORUMS, to prevent the kind of censorship you wanted to impose on others and accused moderators of imposing on you.  NO Peyronies Disease RELATED POSTS ON THIS FORUM ARE EVER DELETED

Furthermore your snide remark about moderators looking to be important is ignorant and unappreciative.  These few men that I can get to dedicate their time unselfishly serving men like you deserve NOTHING EXCEPT YOUR GRATITUDE.  If you don't know how to find your own posts, I am sure that some of the moderators that you insult will teach you how to use the forum if you show a little humility.

Now, if you are having a bad week, I sympathize but you need to gain some composure and ask for help because this makes twice today I have had to address your inappropriate posts.  I am getting impatient with spending this much time dealing with one member's attitude.

Adminstrator
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Hawk on September 05, 2012, 09:23:00 AM
Just a follow-up to my last post.  Apparently Fubar decided to delete his membership after sending me PM's that he owes no one apologies and that maybe I should "sell the forum".  Apparently from his PM's he thinks we have paid moderators that compete with each other and that we make money on the forum.  At any rate, I am disappointed with his decision.  It is a let down when you lose respect for someone.  Since he chose to delete his membership some of his nonsense posts along with my replies will likely be deleted.

Hawk
Administrator
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: fubar on September 12, 2012, 12:48:04 AM
Hawk

I had to come back after seeing this post. What , you think of me as a coward?  That is a big let down that you would address a pm on the open forum. As we all know pm's are personal messages. I know how to use a search bar and find post. I mentioned in my pm my concerns why you should sell the forum. Unlike you i will not mention them as it was a personal message.

I do have to address your comment about me saying moderators being paid to compete for monatary funds. Money,  really? Thats nonsense and we both know this forum is worth much more than money. As for its monatary value it is infact not worth much. However to me and othet suffers it is worth much more.

It is the sole place where we can go among other men and share our knowledge,  pain and discovery. Integrety among pm's also. Those are shared amongst the individuals and not to be changed or moderated to suit ones own purpose, or save face.

Shame on you! Hire does not always mean money ( to engage ) Which could mean appoint i am just putting it out there. Maybe lable or make someone of importance? To impliment a leader. I never said anything about money. So maybe a misunderstanding and you could have sent me a personal message for explanation rather than assuming .

Fubar


Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: fubar on September 12, 2012, 02:52:39 AM
My topic was adult stem cells and regenerative medicine.

Both being of study and importance of Dr. Anthony joseph Atala. Peyronie's the reason he entered Urology.

Just putting it out there.

Just another rediculous post. 

Fubar



Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on September 12, 2012, 09:13:48 AM
Fubar

Welcome back to the forum. :)
I am sure we all can find the way and to be in the relations as we was. :)
We are brothers in arms, we all suffer from this horrible disease that takes a heavy toll on all of us. :(

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: fubar on September 12, 2012, 10:12:20 PM
James

Yes we all live with the effects of this disease. We all share the pain and feel  broken. Our relationship has not changed buy any barrier. You are my friend and always will be. Thank you for your understanding and friendship.

Fubar
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: LMP on October 02, 2012, 07:20:34 AM
Quote from: yyy on August 21, 2012, 06:35:43 PM

At the end of September I will do some PRP injections in my fibrotic plaque here in Italy. They will be totally free as covered by national health service.

Hi - any news on this please. Did you have the PRP injections?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on October 02, 2012, 03:30:40 PM
Just another update, all my original lumps are gone and I still have a bit of a indent/hourglassing located where the lumps use to be but the indent slowly seems to be getting better frustratingly slow i might add.  I did develop another small plaque a few weeks ago just below where the original lumps were but it to appears to be shrinking and getting softer. I will update in another month with my progress.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on October 02, 2012, 06:19:06 PM
Rd,

At the end I will do STEM CELL injections taken by my adipose tissue. The doctor will not do PRP because of a problem with a machinery that cannot sterilize completely don't know what...Have not understood very well...

Now a couple of question for rd:

- Did they do local anesthesia when they used that quite big needle for stem injections?

- What about healing, pain and swelling in the following days?

- After the procedure, when could you have normal erections and normal sexual activity?

Thanks
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on October 02, 2012, 08:07:32 PM
YYY,

I only had stem cell injections not PRP.

As for you questions:

- They did do a local anesthesia I was awake they just numbed me up. I got two of those one for the lipo to get the stem cells and one before they inject them. So I had one in my lower left back. I had mine done on my lower left back right above the hip because I have very little body fat typically it is done from the lower abs. The second was around the lumps that were to be injected.

- The proceedure wasn't bad at all. After reading about the Xfliax injections I was expecting a lot worse. I had no pain or discomfort, I had some brusing and some swelling although they inject a lot into the penis so I'm not sure how much was swelling and how much was from the injection.

- I actually got a errection that night following the proceedure with no pain or discomfort of course it was really weird looking because of all the stem cells and fluid with the stem cells that was injected. I can't answer you for sexual activity as I haven't had any since almost the begining of this condition which had been two years aprox now. I can have sex but it is unpleasent so I have chosen not to have sex until I resolve it.

The worst part and most unfomfortable part was the lipo which wasn't bad just picking the worst part of the whole proceedure. I was actually only sore from the lipo never go sore from the injections. The lipo took a few weeks before it felt normal again.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Sargonnas on October 08, 2012, 05:31:37 AM
This thread its pretty amazing I must say. There has been some REAL progress with RD for what I have been reading. And he didnt even had ED. Maybe if he had the stem cell treatment could have improved that as well, no doubt, because perhaps the stem cells can regenerate blood vessels and nerves. We people with severe ED must face that those are possibilities.

Makes me feel hopeful as I am only 21 and in what it seems acute phase sooo I would love to get those bio-nanites into my old poor thing. Maybe in the future, because right now its pretty much impossible. I have had surgeries that costed my parents double or more the procedure RD got but if no doctor prescribes me the stem cell therapy and it is done in the other side of the Atlantic sea things are different.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on October 08, 2012, 04:12:32 PM
Interesting article regarding stem cells, pros and cons regarding using them. Someone get Nobel Prize on his research on the subject.
Analysis: Reprogrammed cells open new medical window - Yahoo! News (http://news.yahoo.com/analysis-reprogrammed-cells-open-medical-window-150024485.html)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on October 08, 2012, 07:17:46 PM
5th of November is my day. Im scared but also look forward to doing it. It could really change my life. I'll keep you all updated
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Sargonnas on October 08, 2012, 07:28:34 PM
Quote from: yyy on October 08, 2012, 07:17:46 PM
5th of November is my day. Im scared but also look forward to doing it. It could really change my life. I'll keep you all updated

:D Awesome! For sure its gonna benefit you. Are we living the future maybe?? Could a damaged penis be healed by healthy cells injected to it? And more importantly would this treatment somehow reset the inflammatory and possibly autoimmune loop in our penises? I just would like the world situation wasnt the current one. Not good for this kind of research. 2012 UFO´s, please dont change human penis researchs! If something, share your knowledge in repairing sexual organs! lol
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on October 09, 2012, 09:04:11 AM
yyy

Good luck, I will pray for you. Wish you November 5 will be a new beginning :)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on November 05, 2012, 09:14:28 AM
Just another update, all the original lumps treated are gone plus the one on th left side which I developed a few months ago. I still have a dent and the new lump that popped up slightly below were the original is keeps changing. The last time I reported it was soft, well it got hard, feels bigger on some days then smaller on others. I will keep a eye on it and report back in a month.

YYY good luck with your proceedure to day, I know you must be nervous but if it was anything like mine you have nothing to be worried about. The actual injections are a breeze. The must uncomfortable part will be the lipo which isn't all that bad either. It will be great to have your reports on your results to see if you have the same positive results I have had. Hopefully you will and this won't be another treatment that doesn't have a high percentage of success like all the other out.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on November 06, 2012, 08:23:15 AM
Hey guys!

Just come back form the hospital. fortunately Stem cell injections were totally painless. The doctor reached the plaque by inserting the needle diagonally and not going directly into the plaque, to avoid any kind of issues. He told me these injections should give me some improvements,among which more elasticity in 3-4 weeks, but probably they could not be enough to markedly reduce the plaque and curvature. He said will do some PRP injections in March, I think directly into the plaque this time.
By the way, Last night I had a good erection wihout being on Cialis, let's hope it's a good sign.

Speak soon
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on November 06, 2012, 10:11:37 AM
Wish all the best, what's the price?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on November 06, 2012, 04:25:28 PM
totally free thanks to national health service
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: LMP on November 06, 2012, 04:57:14 PM
Can you say where this was?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on November 07, 2012, 06:08:29 AM
At the end of Novembre I will have a follow-up and will ask if I can publish all the details
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Sargonnas on November 07, 2012, 11:37:09 AM
Quote from: yyy on November 06, 2012, 04:25:28 PM
totally free thanks to national health service

No way. Does Italy work that way? Awesome!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on November 07, 2012, 03:57:15 PM
rd,

How long did you wait to see the first results? I mean plaque decrease etc...Thank you
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on November 07, 2012, 07:21:45 PM
It was within the 2-3 month range, the larger of the two treated lumps was gone. I did leave the area alone as much as possible as to not irritate it. Than it was almost a year eactly until I could say the remaining lump that was treated was fully gone. But I only had the one treatment. I would love to get others to maybe speed the process up but I couldn't/can't afford more at this point.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: LMP on November 13, 2012, 04:55:29 PM
Anything to report guy?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on November 14, 2012, 08:09:38 AM
RD how much did you paid? :) & where you've done it?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: LMP on November 14, 2012, 08:42:58 AM
Quote from: LMP on November 13, 2012, 04:55:29 PM
Anything to report guy?

Sorry, meant yyy.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on November 14, 2012, 12:58:37 PM
Quote from: op on November 14, 2012, 08:09:38 AM
RD how much did you paid? :) & where you've done it?

I paid $5500.00 for the proceedure plus hotel and travel expenses. I live on the east coast so it total was around 6100 I think with plane ticket and hotel plus taxi service. I had it done through the California Stem Cell Treatment Center, they have two locations I scheduled before the second was open and traveled to palm springs california the first center to have my proceedure done.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on November 15, 2012, 10:38:38 AM
thanks.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: LMP on November 29, 2012, 09:25:20 AM
Anything to report so far yyy?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on November 29, 2012, 06:01:01 PM
I hope I am wrong but everything I have read about stem cell treatments commercially available today indicate they are a fraud which prey on the vulnerable.

For example:  Stem Cell Fraud: A 60 Minutes investigation - 60 Minutes - CBS News (http://www.cbsnews.com/video/watch/?id=7394380n)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on November 30, 2012, 11:54:54 AM
Quote from: funnyfarm on November 29, 2012, 06:01:01 PM
I hope I am wrong but everything I have read about stem cell treatments commercially available today indicate they are a fraud which prey on the vulnerable.

For example:  Stem Cell Fraud: A 60 Minutes investigation - 60 Minutes - CBS News (http://www.cbsnews.com/video/watch/?id=7394380n)

I saw that as well before having my procedure but if you watch that there are some key differences from what I researched and experience. In the video the procedure was always done over sea's(Not in the USA). Also they promised you the world saying it would 100% cure you. They would also say you need more treatments if if it didn't work if I remember correctly. Where I went I was in the USA, they promised me nothing and said it was experimental. I did have results from one treatment, and when I asked about another they said to wait until I stopped seeing results. They didn't not try to talk me into anything they basically had the attitude of this is what we do and if you have any questions or are interested feel free to ask. The doctors were truthful and admitted they were still learning and just beginning to understand the process. The one in the video is def a scam, I don't believe all are especially the treatment center I went to.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on November 30, 2012, 02:30:58 PM
Thank you for sharing your viewpoint RD, this is very helpful.  Maybe someday this will be a more mainstream option.

Also would love to hear from YYY regaring his progress.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on December 03, 2012, 09:26:50 PM
i have a suspicion that the user, yyy, really didnt get any stem cell treatment and may be lying. i say this cuz he hasnt been responsive to other ppl's questions here. the only one who's been responsive has been rd. i could be wrong and hope i am about yyy. but i'm following my hunches.

rd i got a question for you.. does having lumps, like you did, mean that you had peyronies?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on December 03, 2012, 09:44:40 PM
Also, RD are you satisfied with your results ?  And was the pain resolved or do you still have ongoing issues ?  thanks.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on December 04, 2012, 12:04:42 AM
..
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on December 04, 2012, 09:05:54 AM
Quote from: koolx on December 03, 2012, 09:26:50 PM
i have a suspicion that the user, yyy, really didnt get any stem cell treatment and may be lying. i say this cuz he hasnt been responsive to other ppl's questions here. the only one who's been responsive has been rd. i could be wrong and hope i am about yyy. but i'm following my hunches.

rd i got a question for you.. does having lumps, like you did, mean that you had peyronies?

I went to 3 different urologist who confirmed my lumps as being peyronies. I was hoping it wasn't but all of them confirmed it. That's not including the urologist that did the stem cell injection and my GP.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on December 04, 2012, 09:11:48 AM
Quote from: funnyfarm on December 03, 2012, 09:44:40 PM
Also, RD are you satisfied with your results ?  And was the pain resolved or do you still have ongoing issues ?  thanks.

I'm not 100% satisfied as it isn't 100% resolved. When it is completely 100% gone I will be satisfied 100%. I still have a new lump right below were the original two that were treated were and another tiny one on the left side of my shaft the left one I only notice when I examine the area. I still have slight hour glassing and slight discomfort on the right side from the new lump but not as intense as before. What I would love to do is get another treatment on the remaining lumps and hope for the same result of a 2-3 month resolution to them but I don't have the money to do it right now. I was hoping that YYY would report back so we could compare results to make sure it was the procedure that actually got rid of the original lumps and to rule out it just being spontaneous which I don't believe it was.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on December 04, 2012, 07:00:34 PM
Let's not be so hard on YYY.
He was last active November 22, he wrote he will be at the doctor by the end of November.
He didn't wrote nothing negative until now.
Maybe he is busy and this is the reason for not answering/updating?

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on December 15, 2012, 12:00:41 PM
Hi guys

Not happy to come back and read those kind of comments...I'm not paid to publish here, just want to help everyone has you helped me with many info.
I was busy in this period, and also tried to "forget" my issue and wait to see any possible result.
To prove Im honest, I have to say at the moment I DID NOT have any kind of positive result... After the procedure the doctor told me It was an experimental treatment and He did not feel confident to inject directly inside the plaque (also because of the big needle), but only around it. I have to remind I have some "grafts" under the plaque due to a surgery (nesbit to remove a congenital curvature) so He didn't want to worsen my situation.
He also told me the next attempt will be a PRP injection directly into the plaque.
Next wednesday I will do a follow-up with him to book another procedure and to ask why I still have a little "remain" of fat tissue visible on my penis..in fact it seems the fat did not 100% dissolve

RD please tell me if you also had this kind of issue.

Speak soon
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on December 17, 2012, 08:24:59 AM
YYY I didn't have any fat injected they separated the stem cells from the fat which took about a hour. I did however have what looked like swelling for a few months. I hesitate to call it swelling because it didn't hurt, and they injected a lot volume wise into my plaques which is while it took a few months for that all to go away or for the "swelling" look to disappear. I also had it injected into, around above and below the plaque, he also had to use a bigger gauge needle then he originally planned on because one of the plaques was to hard for the smaller needle to penetrate, I believe it was a 20 gaugle needle he ended up using. The doctor was most concerned with getting the stem cells inside the plaque that seemed most important to him from my perspective. Hope this helps, the area did feel different to the touch until after swelling look was gone.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on December 19, 2012, 10:11:36 AM
yyy

So I am right :)
Every one can be busy and sometimes we need a break for thinking or working.
Wish you better results with the injection in the plaque.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on December 31, 2012, 07:16:44 PM
After 2 years of having this awful condition and trying everything else under the sun with no significant results, I've decided to give stem cell treatment a shot(no pun intended).  I contacted Dr. Lander after reading RD's posts and had a good 15 minute conversation with him.  I described my condition to him, and all the different uro's I've seen and everything I've tried.  My first impression was that he is a doctor that has a passion for this area and is very understanding and insightful.  He says his original intention was to  effectively reverse ed through stem cell injections, but hasn't had much success, but was surprised to see that he's having as much success with peyronies patients.  He quoted me $5500 for the procedure(the same as RD I believe).  He also says he wants to do a combination of stem cells and PRP as well.  As far as I understand He was only using it to treat ed, which I don't have, but is now using it in conjuction with stem cells for Peyronies Disease.  I'll be scheduling the injections for late January, and will be updating periodically with my results. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on December 31, 2012, 09:45:29 PM
Excellent, will Dr Lander be your treating physician ?  He seems to have some pretty good credentials and was a professor of urology. 

Wishing you the best of luck !
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on January 01, 2013, 12:22:25 PM
Chef, that's the same price I was quoted and I got a cheaper prices I believe of 3500 if I needed a follow up. What is interesting is I only got stem cell's injected wasn't a combination of stem cells and prp. Interested in hearing your results with the added prp injections.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on January 02, 2013, 07:12:34 AM
stem cells and PRP... I think it can be the key to improve our situation
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on January 02, 2013, 05:36:51 PM
Quote from: funnyfarm on December 31, 2012, 09:45:29 PM
Excellent, will Dr Lander be your treating physician ?  He seems to have some pretty good credentials and was a professor of urology. 

Wishing you the best of luck !

Thanks, yes Dr. Lander will be doing it on the 23rd of January.  I'm not expecting any miracles, but i really believe we're on the right track with regenerative medicine, not just for Peyronies Disease, but many other diseases as well.

rd and yyy:

I was also intrigued by the combination and perhaps prp contains different growth factors that better activate the stem cells.

Platelet-rich plasma: growth factors and pro- ... [J Periodontol. 2007] - PubMed - NCBI (http://www.ncbi.nlm.nih.gov/pubmed/17397313)
http://www.biomet.com/biologics/international/print/cgf_abstract.pdf

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on January 09, 2013, 05:46:57 AM
Quote from: chefcasey on January 02, 2013, 05:36:51 PM
Thanks, yes Dr. Lander will be doing it on the 23rd of January.  I'm not expecting any miracles, but i really believe we're on the right track with regenerative medicine, not just for Peyronies Disease, but many other diseases as well.

I was also intrigued by the combination and perhaps prp contains different growth factors that better activate the stem cells.

hi chef. i'm thinking about seeing dr. landers also for my ED. he said stem cells havent been helpful for ED. but he suggested a combo of stem cells and prp for me. maybe it'll work. do u know if this combo has helped stem cells combat ED or other conditions better than without prp?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on January 09, 2013, 05:28:59 PM
koolx:

I haven't seen too much written about the combination of both of them.  I do know however prp has been successful on it's own when used particularly for knee and shoulder injuries especially with tendonitis.  My best understanding of the process is that stem cells by themselves are not well activated, meaning they contain the essential building blocks to grow new tissue, but without direction to order them what to do, they don't have much effect.  Prp is rich in growth factors for soft and hard tissues as well smooth muscle and cardiac tissue.  In theory these growth factors can act as the activators for the stem cells. perhaps someone can correct me if I'm wrong, but I believe that's the theory behind combining them. I understand it's still highly experimental, but at this stage in the game there isn't much else on the horizon, so to me it's worth the risk if you can afford the procedure.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on January 13, 2013, 01:24:09 AM
Quote from: chefcasey on January 09, 2013, 05:28:59 PM
koolx:

I haven't seen too much written about the combination of both of them.  I do know however prp has been successful on it's own when used particularly for knee and shoulder injuries especially with tendonitis.  My best understanding of the process is that stem cells by themselves are not well activated, meaning they contain the essential building blocks to grow new tissue, but without direction to order them what to do, they don't have much effect.  Prp is rich in growth factors for soft and hard tissues as well smooth muscle and cardiac tissue.  In theory these growth factors can act as the activators for the stem cells. perhaps someone can correct me if I'm wrong, but I believe that's the theory behind combining them. I understand it's still highly experimental, but at this stage in the game there isn't much else on the horizon, so to me it's worth the risk if you can afford the procedure.

hi chef.. do u know if stem cell treatment and prp can pose risks to the penis? as i said, i'm thinking about getting this combo treatment. but do u know if there are risks or will it make me more impotent?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on January 20, 2013, 02:51:30 AM
Quote from: chefcasey on January 02, 2013, 05:36:51 PM
Thanks, yes Dr. Lander will be doing it on the 23rd of January.  I'm not expecting any miracles, but i really believe we're on the right track with regenerative medicine, not just for Peyronies Disease, but many other diseases as well.

hey chef i wish u lots of luck for ur sc treatment on the 23rd.. i know everything will go well for u.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on January 20, 2013, 12:34:57 PM
koolx:

thanks, I got the appointment set for the 22nd now, so I'll be leaving tomorrow.  From what I've read and from speaking with the doctor, there are no real risks with these types of injections, other than the actual puncture from the needle, which is why you would want a trained urologist like Dr. Lander.  Since the stem cells are adult and are your own, and the blood drawn to to separate the prp is your own, there is no risk when it is injected into your penis.  The same types of procedures are being done on all sorts of tissue injuries especially in sports lately.  I guess you could say there is a risk as well in the wallet, as it isn't cheap, so you may be out 5500 with no results. 

If you research prp and stem cell therapy, you'll find mixed results, but I believe this is from improper use.  Some doctors are using it for everything under the sun including "anti-aging" like facelifts.  Really the goal is to mimic the healing process at an injury site but much quicker and with much more resources (because of the concentration of growth factors).  So for conditions with chronic inflammation and pain in soft tissues like tendonitis and joint pain(I believe tiger woods had some done on his achilles) it seems to have a decent record.  Thats why it seems to me it would work well with peyronies disease(2 years in and still in pain daily). 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Sargonnas on January 20, 2013, 01:10:36 PM
Chefcasey I wish you all the luck with this procedure and I will be looking forward to read improvement reports from you.  ;)

A note about needles and the penis. I got the other week my hard flaccid penis pinched TWICE by a tiny insulin needle to administer Caverject to it (the doctor wanted to make an erected examination) Although the experience was clearly a torture and the nurse had to gave up because I even bled a bit I got NO pain afterwards or any sudden worsening. So if the syringe its small and its done well it shouldnt give problems.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on January 22, 2013, 04:26:46 AM
Quote from: Sargonnas on January 20, 2013, 01:10:36 PM
I got the other week my hard flaccid penis pinched TWICE by a tiny insulin needle to administer Caverject to it (the doctor wanted to make an erected examination) Although the experience was clearly a torture and the nurse had to gave up because I even bled a bit I got NO pain afterwards or any sudden worsening. So if the syringe its small and its done well it shouldnt give problems.

i want to add smthing.. be careful with needles. just cuz u didnt feel any pain and probly never will doesnt mean its safe. using needles can and will result in a bent penis. eventually, theyll result in total erectile dysfunction.

and what exam did they perform on u?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on January 22, 2013, 04:32:26 AM
Quote from: chefcasey on January 20, 2013, 12:34:57 PM
koolx:

If you research prp and stem cell therapy, you'll find mixed results, but I believe this is from improper use.  Some doctors are using it for everything under the sun including "anti-aging" like facelifts.  Really the goal is to mimic the healing process at an injury site but much quicker and with much more resources (because of the concentration of growth factors).  So for conditions with chronic inflammation and pain in soft tissues like tendonitis and joint pain(I believe tiger woods had some done on his achilles) it seems to have a decent record.  Thats why it seems to me it would work well with peyronies disease(2 years in and still in pain daily).

hey chef.. so todays the day? sounds good.. you'll be ok.

i talked to dr. lander about the combo of stem cells with prp in treating ED. he said it hasnt been that succesful with ED. but since the nature of my ED is unique, he said he doesnt know what the outcome may be. so theres a chance it could work. my ED came about from a medication that i took which resulted in a lot of pain and dysfunction. it made the base of my penis look like an hour glass shape. so technically i consider this a phy injury of sorts. so hopefully this combo thats used in healing phy injuries will heal me.

good luck chef.. youre in my prayers.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Sargonnas on January 22, 2013, 07:00:54 AM
Yeah koolx I was just trying to lie to myself but I know perfectly it was the dumbest thing to let the nurse and doctor do that to me. Shame on them, really, although its my responsability as well. I prefer to think it didnt worsen my condition. I cannot believe my luck, its unreal. Anyway, two guys got injections of stem cells here and they only improved so thats why I say one injection with a small needle shouldnt be a problem.

The doctor just wanted to see the huge vein-like bumps I have in erection.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on January 22, 2013, 09:28:49 PM
Thanks for your encouragement guys:

I just got done with the procedure and am back at my hotel.  Overall I'm pleased with how it went.  They harvested the stem cells and prp first.  I have low body fat so it took some doing to get the stem cells from liposuction.  Dr. Lander says that skinnier guys do have a higher concentration of stem cells for some reason and confirmed it, I can't remember the exact number but mine were in the millions which he said was high.   It was pretty uncomfortable, but not painful, feeling the fat getting pulled out of you. 

The actual injections were much less noticeable.  I didn't even feel anything past the initial numbing injection.  I also didn't look where he was injecting exactly as I can't stand to look at my penis getting poked with a needle, but he said he made a lot of passes through the plaque, as he used the swiss cheesing effect. He says he got at least 50 passes so he hit it really well.  Overall the staff was very friendly and professional.

So now time will tell if it helps or not.  I asked him if my lifestyle habits like diet and exercise will have any effect on the way the stem cells respond and he said no, but I'm still going to eat right and exercise right just to be on the safe side. 

Just wanted to update a little.  I am really tired and going to get some rest as I'm going to be sore for a few days. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on January 22, 2013, 10:03:24 PM
Thank you for the detailed report.  I really hope this works out for you Chef !
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on January 23, 2013, 02:30:03 AM
Quote from: chefcasey on January 22, 2013, 09:28:49 PM
Thanks for your encouragement guys:

So now time will tell if it helps or not. 

chef youll be fine.. give us an update soon. i'm sure it'll be a positive one.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on January 23, 2013, 02:35:36 AM
Quote from: Sargonnas on January 22, 2013, 07:00:54 AM
Yeah koolx I was just trying to lie to myself but I know perfectly it was the dumbest thing to let the nurse and doctor do that to me. Shame on them, really, although its my responsability as well. I prefer to think it didnt worsen my condition. I cannot believe my luck, its unreal. Anyway, two guys got injections of stem cells here and they only improved so thats why I say one injection with a small needle shouldnt be a problem.

hey sargonnas! how are you? so you got stem cell treatment for your ED or peyronies? you also mentioned that 2 other men also got stem cell treatment at the same clinic you got it from.. did these men have ED or peyronies?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Sargonnas on January 23, 2013, 03:31:58 AM
LOL no I wish koolx I was talking about the guys on this thread.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on January 23, 2013, 11:11:55 AM
Just wanted to update a little more as last night I was a bit tired and may have left some stuff out:

The type of scarring I have is thin but covers a large area (aprox. half my penis) so it causes an hourglass instead of a curve.  So I asked Dr. Lander if we could harvest enough stem cells to cover if not all the area at least a good portion or the worst of it and he said yes.  Upon examination he could palpitate the scars, which many doctors could not in the past even though I could feel them.  He immediately found the problem area that we both agreed was the worst and he began injecting. All in all I say he covered about 60% of my problem area,  but it was the worst 60%.  So I'm glad that he injected more volume per area than diluting it across the whole area, as I think I'll have a better chance with the higher concentration in the really bad spots.  If I see improvement, then I will have him inject in the remaining area at a later date. 

Upon waking this morning I noticed my stomach area felt a little better than last night and my penis felt a little worse as the anesthetic wore off.  There is a considerable amount of bruising as he said there would be, but less swelling than I expected.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on January 23, 2013, 12:44:10 PM
Chef, I know Dr Lander's specialty is Urology.  Did you happen to ask how many Peyronies Disease patients he has treated with the Stem Cells to date ?

Hang in there I am sure the bruising and swelling will improve soon. Very interesting thread.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on January 23, 2013, 07:06:02 PM
I know for me the swelling took a while to completely go away. I have to admit it was scary to look at me penis as bruised and swollen. Kind of reminded me of when a frog puffs up its chin. I think most of it is fluid though at least from my experience. I am very interested in the results with the prp as he only did stem cells for me when I had it done. I also had difficulty because I was skinny and he had to lipo from above the back side of my left hip and it took a while to get the fat they needed. I never had any discomfort in my penis though even after the numbing agent wore off.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on January 24, 2013, 12:12:06 AM
Quote from: Sargonnas on January 23, 2013, 03:31:58 AM
LOL no I wish koolx I was talking about the guys on this thread.

but did YOU get stem cell treatment for ED or peyronies? if so, how was the treatment so far?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on January 24, 2013, 11:34:48 AM
funnyfarm: I don't know exactly how many he's done, when I talked to him on the phone originally he said he's done quite a few. I believe it as when I went, it was surprisingly a very active facility.  I probably seen about 10 different patients come in and out in the 4 hours I was there, although I think I was the only Peyronies Disease patient that day.

rd: I don't really feel pain, just pressure that's uncomfortable from the swelling.  It looks exactly as you described(frog puff), but the swelling is already down by half since yesterday, although I bet the bruising will take a couple weeks to go away.  The only thing that really hurts if I move the wrong way is the puncture wound from the lipo. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on January 24, 2013, 01:14:43 PM
Thanks Chef, I definitely will look into this in the future if conventional treatments do not work for me. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on January 24, 2013, 03:32:13 PM
Chef sounds like my experience I don't think I had as many injections as you that's why I didn't have the same feelings. I did however have a little pain/discomfort from the lipo area for a good few months. This might be because of the location of my lipo. I would mostly notice it getting in and out of the car and when doing twisting motions.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on January 25, 2013, 08:21:18 AM
yea rd, I'm not sure how many passes he got on you with the needle, but he got a lot on me.  I was woken up a few times last night by erections that were a bit painful from all the injections as he did inject across a large area, so it's still a bit sore.  The swelling however has gone down to almost nothing 3 days later, so I'm pleased about that.  The funny thing is, my flaccid pain I was having on a daily basis has been completely absent the last couple days.  I'm not saying it was the treatment per say as it's gone away on occasion before here and there, but it still feels good. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on January 25, 2013, 11:03:58 PM
Quote from: chefcasey on January 25, 2013, 08:21:18 AM
I was woken up a few times last night by erections that were a bit painful from all the injections as he did inject across a large area, so it's still a bit sore.

hey chef.. its good that ur recovering. were u able to have erections before the treatment?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on January 26, 2013, 08:17:55 AM
Quote from: koolx on January 25, 2013, 11:03:58 PM
Quote from: chefcasey on January 25, 2013, 08:21:18 AM
I was woken up a few times last night by erections that were a bit painful from all the injections as he did inject across a large area, so it's still a bit sore.

hey chef.. its good that ur recovering. were u able to have erections before the treatment?

yes...Peyronies Disease hasn't affected my capacity to get erections, just makes them painful and deformed
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: lukewill on January 26, 2013, 08:27:48 AM
Hey Chef

First of all well done for having the courage to go through with this treatment and taking the bull by the horns and being proactive to tackle Peyronies Disease.

What timeframe have you been given with regard to seeing any positive results?

Best

L
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on January 27, 2013, 11:57:18 AM
Quote from: lukewill on January 26, 2013, 08:27:48 AM

What timeframe have you been given with regard to seeing any positive results?

Best

L

aprox. 3 months
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Sargonnas on January 27, 2013, 12:26:07 PM
I can only wish that this procedure can actually restore penile tissue. If that its possible I wouldnt mind higher or even much higher prices as that would be a damn miracle.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on January 27, 2013, 01:15:39 PM
I agree with you Sargonnas.  How can you put a price on a healthy sex life..   Chef did the doctor say if more than one treatment may be required to achieve the optimum result ?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on January 27, 2013, 02:24:49 PM
Quote from: funnyfarm on January 27, 2013, 01:15:39 PM
I agree with you Sargonnas.  How can you put a price on a healthy sex life..   Chef did the doctor say if more than one treatment may be required to achieve the optimum result ?

I agree 100%.  I would give every penny I have for my old penis back.  Additional treatments will definitely be wanted in my case because we couldn't inject in every area of scarring I have.  This also is dependent on if the first round is successful.  I really must wait a few months to see if there is any change. To me, success is some reversal in my condition.  I am a pretty good control for something like this as nothing has worked for me in over 2 years and I have literally tried everything that had any logical reasoning to it.  If it is successful and I want another round, the doctor will drop the price to 3500, I believe the same went for rd. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on January 28, 2013, 07:34:42 AM
Quote from: chefcasey on January 27, 2013, 02:24:49 PM
Quote from: funnyfarm on January 27, 2013, 01:15:39 PM
I agree with you Sargonnas.  How can you put a price on a healthy sex life..   Chef did the doctor say if more than one treatment may be required to achieve the optimum result ?

I agree 100%.  I would give every penny I have for my old penis back.  Additional treatments will definitely be wanted in my case because we couldn't inject in every area of scarring I have.  This also is dependent on if the first round is successful.  I really must wait a few months to see if there is any change. To me, success is some reversal in my condition.  I am a pretty good control for something like this as nothing has worked for me in over 2 years and I have literally tried everything that had any logical reasoning to it.  If it is successful and I want another round, the doctor will drop the price to 3500, I believe the same went for rd.

That is the same deal they offered me. And I saw results around the 2-3 month range and even up to a year later. After the year I haven't seen any results, and am really thinking about doing a second treatment but I have to get some money saved up before I can.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: lukewill on January 28, 2013, 07:41:14 AM
Hi RD

Apologies if you have already mentioned this before, but may I ask what degree of improvement and results you achieved from your experience with stem cell therapy?

Thanks

L
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on January 28, 2013, 07:19:15 PM
Luke,

The treated plaques and one plaque that developed later near the treated area but not part of it all went away. I developed two new ones though, one just below the treated area and another small one that may have been there before but was only noticeable by touch which I discovered after treatment. It is hard to see doesn't hurt and causes no deformity that I can tell maybe the slightest dent if anything. The remaining one that is noticeable causes hour glassing or a dent. I haven't had any shortening or curve only hour glassing or dents. I have more details if you read from the beginning of this thread I updated as changes happened so it will give you a better idea and time line.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on January 30, 2013, 01:30:58 AM
sargonnas i asked before but i dont think u saw my last post to u..  did u have stem cell therapy done to for peyronies or ED?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Sargonnas on January 30, 2013, 04:23:28 AM
Kool I said to you before that no and I dont see where in this thread I confused you about that one lol I wish I had thats all.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: skunkworks on January 30, 2013, 07:49:06 PM
I wonder if this treatment could be synergistic with xiaflex? Dissolve the plaque then use stem cells to regrow healthy tissue in place of it...
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on January 30, 2013, 10:05:50 PM
skunkworks, that's sounds like a viable solution theoretically. I can't think of why it would not work.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on January 31, 2013, 03:21:25 AM
i was wondering.. is it possible to combine acell and stem cells? maybe this can be effective. i know there are studies doing this for other conditions. maybe this can be a viable solution.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on February 05, 2013, 01:09:25 PM
Hello

ABout stem cell injections, I did not notice any improvements so far, but it's quite normal if you get it peri-plaque and not intra-plaque.

I will get some PRP injections at the beginning of March, this time directly into the plaque in local anethesia.

I will try to improve healing in this way:

- by taking a mix of arginine akg, pycnogenol, CoQ10 and Vitamin E
- by using a traction device just bought, it's much more comfortable than normal ones, I will write its name if it's permitted
- by alternating 15 minutes of "jelquing exercices" and 15 minutes of VED

After 2 months I will repeat the PRP injections let's see what happens...

By the way, how many IU of VitE do you suggest for peyronies? Thank you
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on February 05, 2013, 02:50:28 PM
fracture for jelquing? very strange mate..I found them on a free forum, in which people can write also about injuries etc...I think if you do it correctly and slowly you won't have any problems. For example, penis must not be 100% erect, this is one of the main rules.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Sargonnas on February 05, 2013, 03:42:36 PM
Dont do jelquing, stretching or any other stupid crap. Only in this forum you can find four or more people injured by those damn exercises and I have seen many more scathered around other boards. WOMEN DOESNT CARE IF YOUR PENIS ITS NORMAL SIZE AND WORKS FINE. If I could come back in time I would spit on the idea of torturing my penis to gain a few miserable cms. I lost a lot of my sensivity, now I have CPPS (hard flaccid its CPPS) that can be strong enough some days to make me moan and shout , spontaneous erections are a dream of the past (except maybe 5 every month lol) and I cannot have real orgasms anymore. I am not impotent but my sexual life its damaged, maybe forever. Oh yeah and I gained 1,5 cms of length and maybe some girth. No worth it.

Dont believe me? Look for "hard flaccid" in the PEgym forum. A LOT of those cases were caused by... penis enlargement exercises.

If you do the exercises well they supposedly arent harmful. But its VERY EASY to do them wrong. Im radically against all this now and I think these boards should be all be taken down and every bit of info about "PE".  ;)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on February 05, 2013, 04:31:31 PM
OK maybe it's better to stop them...I will continue only with the extender,it was suggested by several urologists that I consulted.
My real big problem is not the plaque itself but the loss of lenght... + 1,5cm is a dream for me
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on February 06, 2013, 08:02:01 AM
Quote from: yyy on February 05, 2013, 01:09:25 PM

- by alternating 15 minutes of "jelquing exercices" and 15 minutes of VED


i STRONGLY suggest that you NOT do any jelqing or p/e exercises. theyre VERY dangerous and can lead to absolute impotence. there are tons of people who have tried jelqs and are now impotent for life. any uro will tell u that these are dangerous penis exercises and should be avoided.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Sargonnas on February 08, 2013, 05:43:22 AM
People are waking up to the fact that Penis Enlargement exercises are a trap, and I am glad. I wish someone would have told me back in the day. I didnt know they erase comments or logs about negative experiences in those forums but it doesnt surprise me a bit now.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on February 12, 2013, 09:17:33 AM
I'm starting to get a little scared about the procedure.
You know, my lump is caused by a surgery, I've got some sutures around/inside it, I don't want to worsen the situation by injecting into it. At the same time I'd like to change things,I can't keep living this way.
As I've read, a small lump is quite normal after a Nesbit procedure, but mine is quite big and clearly palpable...Hope situation will improve with PRP  ::)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on February 12, 2013, 12:50:32 PM
Is it possible pentox could soften it ?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on February 12, 2013, 04:09:09 PM
I think it's quite useless in my case, and most of all it caused me lots of side effects such as severe diarrhea and gastric issues
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on February 19, 2013, 09:52:09 PM
for those who had the PRP with stem cell therapy, have u noticed better and stiffer erections?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on February 23, 2013, 06:22:59 PM
Just to update:  It's been one month since my prp/stem cell combo.  I have nothing to report, no change in condition good or bad.  I kind of hoped to see something positive by now, but there's still about 2 months of a window left to see something.  Otherwise I'll have concluded it was not a success.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on February 25, 2013, 07:30:02 PM
Quote from: chefcasey on February 23, 2013, 06:22:59 PM
Just to update:  It's been one month since my prp/stem cell combo.  I have nothing to report, no change in condition good or bad.  I kind of hoped to see something positive by now, but there's still about 2 months of a window left to see something.  Otherwise I'll have concluded it was not a success.

just give it another month. dr. lander recommends that one wait at least 3 months for  tentative progress. dont give up.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on February 27, 2013, 07:18:57 AM
Quote from: chefcasey on February 23, 2013, 06:22:59 PM
Just to update:  It's been one month since my prp/stem cell combo.  I have nothing to report, no change in condition good or bad.  I kind of hoped to see something positive by now, but there's still about 2 months of a window left to see something.  Otherwise I'll have concluded it was not a success.

Chef like you I was disappointed at the month mark after having the treatment. I didn't see results until the 2-3 month range. Then again aprox a year from the procedure.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on March 02, 2013, 02:22:33 PM
Quote from: rd on February 27, 2013, 07:18:57 AM
Quote from: chefcasey on February 23, 2013, 06:22:59 PM
Just to update:  It's been one month since my prp/stem cell combo.  I have nothing to report, no change in condition good or bad.  I kind of hoped to see something positive by now, but there's still about 2 months of a window left to see something.  Otherwise I'll have concluded it was not a success.

hey rd.. has the treatment helped u get more frequesnt and better erections?

Chef like you I was disappointed at the month mark after having the treatment. I didn't see results until the 2-3 month range. Then again aprox a year from the surgery.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on March 02, 2013, 02:23:30 PM
Quote from: rd on February 27, 2013, 07:18:57 AM
Quote from: chefcasey on February 23, 2013, 06:22:59 PM
Just to update:  It's been one month since my prp/stem cell combo.  I have nothing to report, no change in condition good or bad.  I kind of hoped to see something positive by now, but there's still about 2 months of a window left to see something.  Otherwise I'll have concluded it was not a success.

Chef like you I was disappointed at the month mark after having the treatment. I didn't see results until the 2-3 month range. Then again aprox a year from the surgery.

hey rd.. has the treatment helped u get more frequesnt and better erections?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Hawk on March 02, 2013, 04:14:06 PM
Guys,

Lets not be quoting quotes of quotes.  The "reply" button is the standard button used for posting, not the quote button. 

Hawk
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on March 02, 2013, 05:02:24 PM
Never had a problem with errections Koolx, they have always been normal. I just had dents(hour glassing) and pain/discomfort.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on March 04, 2013, 12:02:07 AM
Quote from: rd on March 02, 2013, 05:02:24 PM
Never had a problem with errections Koolx, they have always been normal. I just had dents(hour glassing) and pain/discomfort.

yes i know that.. but have u noticed better erections after the treatment?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on March 04, 2013, 06:59:03 AM
No difference in erections they have always been rock hard and easy to achive
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on March 05, 2013, 06:56:40 PM
has anyone here felt they had better erections after stem cell treatment?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on March 11, 2013, 01:30:43 PM
important update,

Starting from the 3rd month I got fuller and improved erections, but I don't know if it's thanks to stem cells. I'm not taking any supplement or cialis at the moment.
Also length seems to be improved, but maybe only because Im getting fuller erections.
Plaque and curvatire seems to be the same as before, I remember he did not inject into it.
At the end of March I will get PRP injections, pretty confident at the moment! Im having some improvements, this is great!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on March 11, 2013, 11:55:43 PM
Thanks for sharing the positive news !
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on March 13, 2013, 02:47:50 PM
YYY,

if erections improved to the point where length increased in size given you didnt take any pills, i'd attribute it to the stem cells.

you're doing better.

Quote in violation of forum rules deleted by administrator.  Double post deleted!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: user of no names on March 20, 2013, 01:50:53 PM
YYY, chef casey or rd How did they know where the plaques where?  Did they do a penile duplex ultrasound?  I have an appointment with Dr Levine on friday to get his opinion.  I was waiting for xiaflex to come out or something like stem cells before doing surgery.  I may possibly do the stem cell procedure if more positive results occur from you guys.  I will bring up stem cells and prp with Dr Levine to see what his opinion is.  This disease sucks but need to do something.
Thanks jesse
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on March 20, 2013, 07:09:51 PM
peyroniesmn:

The doctor was able to feel where my scar tissue was upon examination and could see it as my deformity is present in the flaccid state.  He recognized it within seconds and confirmed with me that this was the area, and I confirmed before the injections.  I suppose that if it is hard to spot or not palpable, you could use an ultrasound as a guide.  I was also a patient of Levine's at one time and recieved the duplex ultrasound.  It was helpful in confirming that I had no calcification or blood flow problems, but other than that it can't really see what's going on deep in the tissues.  He was very understanding and thorough, but had nothing more to offer me than pentox and and a recommendation for traction.  Since nothing else helped, I decided to go through with stem cells, sort of a last ditch effort since I'm not a candidate for xiaflex or surgery.  I can tell you that it's been aprox. 2 months since my treatment and I see no changes yet in anything so I don't know if it will be successful or not.  I can also tell you the procedure is completely safe(at least with Dr. Lander).  Any soreness, bruising, swelling, or pain I had with the injections and accompanying lipo is completely gone, sometimes I forget I even had it done.  Hope this helps.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on March 20, 2013, 08:52:30 PM
hey yyy... did u have any Erectile Disfunction issues before taking the stem cell treatment?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on March 21, 2013, 08:56:38 AM
Well, erections were not strong before, now they are just a little better but not completely satisfactory
My lump is quite big and completely palpable so no need to look for it
Next tuesday I will get PRP injections into the plaque, at last
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on March 28, 2013, 02:03:35 PM
hey yyy... hope u had a good prp session with no rpoblems..
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on March 28, 2013, 05:32:16 PM
Sorry, not connected to the topic. :(
It will be nice that also the native English speaking people will use the speller before posting. The posts will be more understandable especially for the not native English speakers. ;)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on March 29, 2013, 05:58:57 PM
Hi guys

What I did was a combo stem cells + prp. They have a new machinery that divided blood from fat tissue, then the doctor injected both into the lump. At the moment I feel some pain just when I touch the lump. Bend seems to be already reduced a little but erections are not complete at the moment, I mean it does not lenghten as before but I think it's due to small bruise I got
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on April 02, 2013, 06:11:24 PM
Hi, i've found interesting article on other forum:
High Rates Of Sexual Dysfunction Reported After Stem Cell Transplantation - The MDS Beacon (http://www.mdsbeacon.com/news/2011/09/15/high-rates-of-sexual-dysfunction-reported-after-stem-cell-transplantation/)

p.s. 48% reported dissatisfaction with their sexual function after stem cell transplantation.

Any comments from already did the therapy?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on April 02, 2013, 10:40:04 PM
myelodys­plastic syndrome ??
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on April 03, 2013, 01:50:19 AM
logically this is same stem cell therapy & healing process, just disease is different.

Quote from: james1947 on March 28, 2013, 05:32:16 PM
Sorry, not connected to the topic. :(
It will be nice that also the native English speaking people will use the speller before posting. The posts will be more understandable especially for the not native English speakers. ;)

James

Sorry James, I guess it was for me. I'm not native. Also, I was on the emotional rush because of my problem but wanted to help about jeqing dangers... I've deleted these messages. because didn't liked these too. (currently)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Hawk on April 03, 2013, 06:31:00 AM
OP, That is a pretty interesting article on sexual dysfunction after stem cell transplantation.  It is potentially a huge issue for a treatment that raised so much hope for people with many different conditions.  It also seems they were talking about all stem cell transplant not just for MDS ???

Thanks for posting that link
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 09, 2013, 11:26:15 PM
Quote from: op on April 02, 2013, 06:11:24 PM
Hi, i've found interesting article on other forum:
High Rates Of Sexual Dysfunction Reported After Stem Cell Transplantation - The MDS Beacon (http://www.mdsbeacon.com/news/2011/09/15/high-rates-of-sexual-dysfunction-reported-after-stem-cell-transplantation/)

p.s. 48% reported dissatisfaction with their sexual function after stem cell transplantation.

Any comments from already did the therapy?

so hold up.. does this men that we're all in trouble if we go for stem cell treatment?? i was actually thinking about getting stem cell treatment as part of a clinical trial. but now i'm having 2nd doubts as per the article. i dont kno what to do now.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on April 10, 2013, 12:26:04 AM
I had it coming up on 2 years ago. I haven't had any of the symptoms mentioned in the article
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on April 10, 2013, 05:13:49 AM
OP

It was not for you, it was for native speaking English that sometimes missing letters in they post makes us, not native speaking English not to understand the words. :)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 10, 2013, 03:18:01 PM
has anyone here had an hour glass effect on their penis at all?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Hawk on April 10, 2013, 03:39:19 PM
If you mean anyone on the forum the answer is hundreds.  That's why there is such a phrase.  It is named because it is a common manifestation of Peyronies Disease deformity.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 11, 2013, 09:03:27 PM
Quote from: Hawk on April 10, 2013, 03:39:19 PM
If you mean anyone on the forum the answer is hundreds.  That's why there is such a phrase.  It is named because it is a common manifestation of Peyronies Disease deformity.

hi hawk.. i got an hour glass deformity after taking a medication called respirodol. much of the formation left.. but an impression of it still remains. i was wondering if maybe stem cells can correct it.. and just to let u know, i dont have peyronies or fibrosis
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: skunkworks on April 11, 2013, 09:23:23 PM
Quote from: koolx on April 11, 2013, 09:03:27 PM
Quote from: Hawk on April 10, 2013, 03:39:19 PM
If you mean anyone on the forum the answer is hundreds.  That's why there is such a phrase.  It is named because it is a common manifestation of Peyronies Disease deformity.

hi hawk.. i got an hour glass deformity after taking a medication called respirodol. much of the formation left.. but an impression of it still remains. i was wondering if maybe stem cells can correct it.. and just to let u know, i dont have peyronies or fibrosis

It would be surprising if there was no fibrosis, isn't the fibrosis what causes the hourglass effect?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Hawk on April 11, 2013, 09:28:39 PM
Koolx,

You say you have hourglass deformity, that you have a 20 degree curve, that you are interested in Xiaflx trials, then you say you have no fibrosis or Peyronies Disease.  What do you think is causing your penile deformity if it is not plaque?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Hawk on April 11, 2013, 09:33:42 PM
Koolx,

You say you have hourglass deformity, that you have a 20 degree curve, that you are interested in Xiaflx trials, then you say you have no fibrosis or Peyronies Disease.  What do you think is causing your penile deformity if it is not plaque?  Why would you even be on a Peyronies Disease forum making 5 posts if you have been diagnosed not to have Peyronies Disease or fibrosis ???  All of these facts just don't add up or fit together.  If you did actually develop a 20 degree curve and an hourglass deformity you do very very likely have Peyronies Disease.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 12, 2013, 01:52:50 PM
Quote, in violation of forum rules, removed by Administrator .

i dont have peyronies and i dont have fibrosis. thats what my uro says after the doppler tests results revealed none of those things. he said i have scar tissue which caused the bend. if u want to challenge him on this, since u sound a bit antogonitic about it, youre more than welcome to and i'll furnish u his number and u can call him to discuss it. and if u read thoroughly, i said my hour glass is mostly gone, what remains is an impression that i can feel. therefore, i dont very very likely have peyronies disease. i'm sure since hes the doc i believe he would know more about it than anyone on a forum.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on April 12, 2013, 03:44:14 PM
Hey All,

I would like to add to YYY's posts here as I just got my first PRP treatment yesterday. I will say that for the first time in about 2 months I got a natural erection last night. It felt a bit firmer than normal and the fairly large indention appears already to be filling in. I'm shocked after just a little over 12 hours that I've had this type of response. I'm hoping that it will stay this way and that it's not a short term thing. My next treatment will be in 2 months if all goes well with this one. I'll stay up to date as things progress.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on April 12, 2013, 06:54:41 PM
rellisacct

Good news :)
Pray for you that things will just get better.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Hawk on April 12, 2013, 08:03:44 PM
Koolx,  Consider this a warning. Do NOT hit the quote button to reply to a post that is right under the post you are making.  It repeats the entire post again.  The forum rules address this.  You have be told about this before but I notice that most of your posts have quotes in them except the ones where I have taken the time to remove them.  When you want to post click on the Reply button. 

If you do not understand the issue then just ask and we will do all we cant to make it clear.

Hawk
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 13, 2013, 08:11:20 PM
hey rellisacct.. glad to hear about a firmer or firm erection. hope its not a placebo in your head. how were your erections before treatment? and did treatment involve stem cells also?


yyy... how are your erections coming along so far?


ok hawk.. no prob.. but how many posts after i see a quote i want to post should i quote it?

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Hawk on April 13, 2013, 10:09:41 PM
Quote from: Hawk on August 12, 2005, 11:08:40 AM
7. Limited Use of the Quote Button - Normally we should use the REPLY button to reply to a post.  We can use the quote button over a members post only when we want to quote a small portion of another post.  We can also use it when responding to anything that was previously posted BUT NOT when we are responding to the the post immediately before our own post in the same topic.  When we do use the quote button we should trim the quote down so entire posts are not repeated. That way the reader can more easily follow the conversation. /b] 

I think the rules are kind of clear.  We always give the benefit of the doubt here if you are in a grey area but as you can see by any reading you were outside of any grey area, especially since I posted before and brought this to your attention.  I can only guess you have never read the rules so it would be good to click on the link and read the entire document.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on April 14, 2013, 09:46:01 PM
Thanks James & Koolx, I appreciate the thoughts and prayers.

Koolx - some quick background...I've had this crap for 11 years and have had various luck with various treatments but nothing lasting. This change is definitely not a placebo as I have proof of the before and after so far. I had a large indention in the left corpora tissue, mid shaft and post injection the indention has noticeably shrunk. I have had major girth shrinkage all along the right and left shaft of my penis, but it appears that the indention might be improving and this has definitely improved the erection. Before injection, very weak erections, none natural (if you can call them erections). Post injection (I'm supposed to try to not have erections for a week) I can't help but get 2 or 3 a night and they actually wake me up because I'm not used to that.

No stem cells, only PRP right now. I'm looking at possibly adding stem cells to the mix.

I did have turtle necking and tightness to the left most of the time...now the tightness is on the right which shows that there is tissue growth on the left.

I have also significantly improved my diet over the past month which may be a factor in how well the tissue is responding to the injection, but that's just speculation.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 15, 2013, 04:38:10 PM
hey rellisacct.. very content to hear this good news from u. i imagine the quality of ur erections post prp has been very firm and penetratable for sex as you imply. i got 3 questions for u:

1 - my penis girth has shrunk in size also. as a result, my erections are weak. i read that it could be due to low testosterone. but not sure. did u have low testosterone at any point?

2 - can u tell me where u got this prp treatment from? and please tell me also the cost.

3 - do u have spontaneous erections during the day?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on April 15, 2013, 06:35:55 PM
Thanks koolx, I hope that the change is permanent and not just teasing me like some other treatments I've tried. I think that my uro was a one shot one kill kinda guy because he nailed the plaque dead center. He basically put the full dose of PRP into the one area of indention and I can tell a difference in the tightness of the tissue there.

1) Based on blood tests, I don't have low T. My penis has been through hell with sex injuries as the first time was girl on top and she came down on it wrong..."snap". Other times smaller injuries due to the penis not being as rigid as it was pre-injury. Basically I think the plague runs through both the right and left shafts all up and down the penis with worse areas than others.

2) PRP treatment was from Wake Forest University with Dr. Terlecki. I highly advise that anyone in the Southeast go see him. If nothing else, he will inspire you as he was one of the main associate researchers behind the rabbit tissue engineering replacements. Cost I think is $1,500 a pop, but I'm going to try to work with him on that. That's not exactly cheap for the small area of improvement. It would take about $30k to cover everything that I would probably need to get done to get back to perfect function at this rate.

3) I don't during the day but at night I do. I'm thinking that if he basically just did a huge carpet bombing of my penis with PRP injection after PRP injection that my functionality could easily improve by 50% at this rate. I'm just extremely excited that the tightness has gone from the left side of my penis to the right and that the turtle necking has decreased a good bit. I actually sometimes have a non-hard flaccid penis whereas it usually is hard even when it's supposed to be flaccid (non-erect).
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on April 16, 2013, 05:18:22 PM
Today I saw my urologist for an ultrasound 3 week post.
He told me he did only a stem cell procedure not together with prp: he divided the lump in two parts with the needle then injected the stem cells between the two parts. He said my situation is still in progress at least for a month.
Plaque seems to be more or less the same, as well as the bend, but I got some improvements about quality of erections and tissues stretching; for example morning erections came back nealry every day after the treatment.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on April 16, 2013, 05:46:16 PM
It seems like some of the PRP stem cell reports are encouraging lately.  Thanks for the info guys !
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on April 17, 2013, 02:42:13 PM
YYY, glad to hear that things are progressing for you as well.

Do you know why the uro decided to just do stem cells vs a stem cell/PRP mix? I've been looking into adding stem cells and not sure what the uro's are trying to gain out of just doing stem cells or just doing PRP vs using a mix of both.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 17, 2013, 03:03:56 PM
hi rellisacct.. i'm confused here. u said that treatment was $1,500. but then u said that it covers $30,000?? i dont get it.. do u mean that u have to go back for treatments totalling $30,000? that wouldnt make sense. also, why didnt u opt for stem cell treatment also?

one last thing.. i contacted Dr. Terlecki.. one snooty bitch of a nurse was disrespectful to me. she didnt know what treatment approaches he uses though she said she his nurse, then when i asked to speak to another nurse with more info, she got mad and exclaimed to her colleague that i "was annoying her." i was then transferred to another nurse. i told her about the disrespect of the other nurse, and she took it lightly. i dont understand what hospital this is but its staff are completely out of control. anyway, i'll try back again tomorrow.

yyy, its good that your erections are coming back to life again. i appreciate u telling us that. but u had stem cells done 3 months ago. i think when u said 3 weeks in your last post that it was a typo. btw, do u think your erections are firm enough for sex? do u get erections in the day also?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on April 17, 2013, 04:11:51 PM
No, let me clarify. Each injection runs about $1,500 because it's not covered by insurance as it is an expiremental treatment. The one treatment was very helpful, however, it's not an absolute cure. I was just making the point that if I needed a ton of injections, that it would be extremely expensive. It could be $10,000, $20,000, $30,000 or who knows. But trust me, if I can get a response like this from each injection, then I would do whatever it takes to raise the money.

I wasn't given the option for stem cells with Wake Forest. He just offered to try the PRP injection. If I decide to start up with stem cells too, then I'll have to go to the California Stem Cell Center that a few others have spoken about. I still want to do a little more research on that first.

As for the nurses, I'm sorry that you had to go through that. They have been nothing but respectful to me each time I have been there. Maybe they were extremely busy or just had an off day. 

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on April 17, 2013, 04:37:26 PM
My uro told me that this kind of stem cells using this machine should be 10 times more effective than PRP so he decided to do it.

My first stem cell was in November but not with this new machine and not directly into the plaque, my second one was 3 weeks ago.

Next time I will do only some PRP injections because he said there's no need to repeat a stem cell treatment at the moment, PRP can be enough.

I remember Im using VED, traction and supllements such as Accoleit and vitE/coQ10/Propolis plus Diclofenac spray twice a day
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Crooked_Stick on April 17, 2013, 09:08:16 PM
I was reading last week about bone marrow injections to heal ruptured lower back disks. Bone marrow taken from the hip is rich in stem cells and can be refined quickley using a centrifuge. It seems this could provide another source for stem cell treatment for peyronie's. Any thoughts?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: RoyHobbs on April 17, 2013, 09:20:40 PM
I dunno. He's Boar certified? I've never trusted boars. Are the boars wild or in captivity you think?  ;)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on April 18, 2013, 10:16:59 AM
It's possible, but I don't know if bone marrow stem cells would have any extra benefit compared to adipose derived. I do know that I've read a few different articles stating that one reason bone marrow stem cells aren't used more often is because they are more difficult to harvest, more painful/uncomfortable to the patient, and you get way lower volumes of stem cells. It's worth looking into though.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 18, 2013, 07:37:54 PM
yyy, the new machine at the cali stem cell clinic is a shock wave machine. dr. lander told me that it stimulates the penis. he also said that it "stimulates" injected stem cells in the penis. from what i read about it, it does rehab the penis. but i highly doubt that it stimulates injected stem cells. maybe i heard him wrong when he explained it. he offers this treatment in combo with PRP.

but i had asked u before but u didnt reply.. are your erections penetrable enough for sex now? and were they too soft before u had the stem cell treatment?

also, this is a questions for everyone.. has anyone here had low testosterone prior to any treatment?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: LWillisjr on April 23, 2013, 09:37:41 PM
I split this topic. It was going down the path of debating best and worst health care systems. Let's keep this one back on the stem cell topic.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on April 23, 2013, 11:46:31 PM
I agree with lwillis, there seems to be some promising results from Stem Cell/PRP injections and we should focus on that.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 24, 2013, 03:56:59 PM
hi rellisacct,

1) how are ur erections coming along? any daytime erections yet?

2) i dont think i asked u about the quality of ur erections. hows the quality if u dont mind me asking?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on April 24, 2013, 04:24:24 PM
Hey Koolx,

I can definitely tell a HUGE difference in quality of erections. The main problem I have is the scarring all along the shaft which keeps me from having a full thick erection like it used to be, but the erection quality has improved about 30-40% from pre-injection (much better bloodflow vs having a bottleneck). I can also tell that there has been significant thickening at the point of injection as opposed to the rest of the shaft which is great. Actually, where the injection was put was the worst part of my penis but is probably the best part now.

The only problem now is that there is still so much of my penis left to improve that it will be an uphill battle, but I'm finally for the first time in 3-4 years excited about my prospects.

No natural daytime erections yet, but if I think for a couple of minutes about the girl I was with this past weekend, then we have liftoff. ;)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on April 24, 2013, 04:47:52 PM
I also noticed a thickening of the penis in the zone of the lump. now shape seems to be more regular.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: damian on April 24, 2013, 05:09:47 PM
hey rellisacct

What do you mean with "scarring all along the shaft"? Do you mean scar tissue over the whole shaft or just on several places?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 24, 2013, 08:19:45 PM
rellisacct, great to hear the excellent progress. dont worry about the other stuff.. just remember that u recently just had this done so it takes time to heal further. and u can repeat prp sessions if u need to in the future which will enhance more progress if need be.

yyy, keep up the good work. ur progressing as well. very important.

i think within 5 yrs we'll alll see a major breakthrough with stem cells and prp regarding ED. no question about it.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on April 24, 2013, 10:08:51 PM
Koolx, I really pray that you're right. If we can perfect the process, we all have a real shot at seeing some amazing things happen in the next few years. Maybe not a 100% cure but sometimes small improvements are all that is needed.

Ushtipack... It is kind of hard to explain. The left shaft has significant scarring from the base to the tip all along the shaft. There was a large indention before injection, but now that's gone and good tissue has taken over...woohoo!!! The right shaft has significant scarring at the base but expands better than the left side. The tip of the right shaft has no scarring. The result is 40% less girth but the length is still the same as before. Funny how this crap affects everyone differently.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on April 25, 2013, 12:08:21 AM
Congradulations guys !  We could all use some good news around here !  You are brave and I thank you greatly for sharing your encouraging stories.   I can only wonder if one day this will surpass surgery as the preferred treatment for peyronies in cases where pentox does not help. 

I noticed that George started this thread just a short 3.5 yrs ago and at the time it was described as being just a little more tangible than science fiction.  Things have progressed very quickly ! 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on April 25, 2013, 01:52:17 PM
Well it's been roughly 3 months since my stem cell treatment and I'm sorry to say there is no change in my condition. :'( Maybe it will take some more time, but Dr. Lander said I should have seen something, anything by now.  I'm also starting to think that my scarring is deeper than I previously thought, like along the septum, which may explain why I've lost only girth and not length, and if that's the case, that could be a reason to why the treatment may not have worked.  In any case I am disappointed but not surprised.  I knew full well going in that this is still experimental.  It's really nice to see at least that's its worked for others on here and I wish you all the best. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on April 25, 2013, 03:14:56 PM
Casey,

I'm sorry to hear that things haven't been improving for you at all. I will say that I am in no means close to cured by any stretch of the imagination, but I luckily have been able to see a tangible difference after just one PRP session. I personally think that there are 2 things that made the injection successful...

1) I significantly improved my diet about a month and a half before the injection. No sugar, no breads, no red meats, yes fruits, yes vegetables, yes lean chicken/turkey.

2) The full PRP dose went into one area (worst area). I didn't have multiple injections everywhere so there was a ton of growth factors concentrated in one place.

Maybe these types of things make a difference or maybe they don't. If you can afford it, I wouldn't give up just yet. I would atleast try the 2 things that I mentioned above before calling it quits.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 25, 2013, 03:57:28 PM
i noticed something of significance here. on one hand, casey had both stem cells and prp. and rellisacct had only prp. in casey's case, he didnt show improvement. in rellisacct's case, he shows massive improvement. i'm wondering if just prp alone is just enough. maybe its just better to just have prp and leave out stem cells.

how many of u had both stem cells and prp?? and let us know if u improved or not from this combo.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on April 25, 2013, 06:21:46 PM
rellisact:

I also changed my diet before the procedure up to the present along the same lines (no refined sugars, no wheat, lots of organic fruits and veggies) as well as no alcohol or anything unhealthy.  I knew I should keep myself the best control as possible because at the time I believe I was the only one on here getting the combo(prp+stem cells).  Like you I also had the injections located in a concentrated area, with the doctor using roughly 40-50 passes with the needle.  I asked the doctor what I should do to try to increase my chances of success post-procedure and he said nothing.  In his words "the stem cells or going to do what they do, and there's no way to get them to do otherwise".

I understood that a good portion of men won't respond to this as the doctor told me, if we all did respond, we'd have a true cure for this disease and problem solved for us all.  He said the people who respond best are those whose disease or inflammation is most "active", because that's what really triggers the growth factors to go to work, if they don't sense an injury, they'll just assume its healthy tissue and the growth factors will be wasted.  I've had Peyronies Disease for over 2 years now, but technically it is still progressing but not as much, so maybe it was too late for something like that to be effective.  Either way I don't regret doing it as I would gladly give something a chance that has some real science behind to beat this thing than not try at all.  But do keep us posted on your progress and good luck!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on April 25, 2013, 06:37:17 PM
koolx:

I don't want to conclude yet for sure that nothing happened.  I don't know, the body is complex and we're all different so it could be that its working slower in me than others.  I just wanted to update at the 3 month mark.  I also now suspect that the real problem is deeper in the shaft and I don't think the doctor got in that deep with the needle.  I will continue to watch and wait a few more months before I completely conclude that it was not successful and will keep everyone posted if something changes.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on April 25, 2013, 07:57:52 PM
Thank you for the detailed info from your doctor Chef.  Be patient and remember the treatment will be refined as more people are treated.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on April 25, 2013, 11:04:06 PM
Chef, thanks for the follow up. I'm thinking and hoping that the plaque/scar tissue may just be deep in the shaft and he didn't hit the real problem area. I have had this for 11 years now and am seeing progress. I know that my plaques are calcified but there is still tissue growth. I know for a fact that its not in the active phase and that I've been at this point for a while, so there is still hope.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on April 26, 2013, 06:56:30 AM
Chef don't give up hope I had one lump resolve a year after stem cell treatment.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 26, 2013, 03:09:21 PM
hi chef and everyone,

u implied that if therapy doesnt sense tissue thats not damaged enough for repair, that the therapy will ignore it. just to let u know, i got an hour glass formation thats not that bad (but not good if i got it). and i got a bend to one side from penile injections. the bend is not bad, but again, its not good if i got it. the bend is about 25 degrees to the side. my erections are soft and sometimes "hard" in the morning. do u think prp/stem cells can help in my case?

hope anyone can chime in and answer this question.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on April 26, 2013, 04:25:20 PM
rellisact, funnyfarm, and rd thanks for your words of encouragement.

koolx: Yes this was Dr. Landers thoughts on stem cell therapy.  He told me he had not had good results with men whose plaques were no longer progressing or not causing pain.  The science behind it is that if scar tissue becomes fully formed and matured with no additional inflammatory processes still going on, stem cells won't recognize it as damaged tissue and won't repair it, because your body isn't telling the stem cells that you need repairing.  Now what exactly is the criteria that your body uses to activate wound healing? I don't know, it's a complex process, but the fact that rellisact has had issues for 11 years and saw improvement tells me this process is still not well understood. 

As far as stem cells helping in your case, I couldn't say.  I too have somewhat of an hour glass shape but I now suspect the scar is more in the septum rather than the outside of the tunica, which can cause hourglassing, a good thing to keep in mind when looking into any type of injections.  I don't believe there is a good success rate with ED but something may have changed since the last time I talked to Dr. Lander.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on April 26, 2013, 05:49:30 PM
I checked in with Dr. Landers about maybe getting a follow up and if the procedure had changed at all, after hearing about prp and he sent me the attached file. Apparently he is using shockwave therapy in combination with stem cells was curious as to thoughts on this. I thought shockwave therapy was proven not to be effective for peyronies.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 29, 2013, 04:59:30 PM
rd,

dr. landers also indicated to me over the phone that shock wave therapy activates stem cells/prp in the penis. i seriously have to doubt this. but just to be fair to him, its possible that i misheard  him. maybe he can reiterate to you whether this statement is correct or not.

on a side note, it appears that god hates us. i cant believe that the creator who "loves us" wouldnt heal us of these penile conditions. after all, his commandment is to "be fruitful and multiply." i thought it was interesting to state this.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on April 30, 2013, 05:05:56 PM
chefcasey - don't loose hope! There is other therapies over today, which can heal the penile cells (they claiming that it could), but most are with potential of side affects, for example. sound wave/shock wave therapies, silver therapies, but for me most interesting is "living cell" therapy, but as I understood stem cell therapy is on top right now.

Anyway this is nice to see some results from others! Thumb up

p.s. I guess after stem cell therapy patients need to be active, for better cells circulation. What I want to say, stem cells is not a miracle we need to put some energy too, same with minds over healing time, less stress & so on, because all this developing nerve system in our body. Anyway this is just mine philosophy based on science information, but please feel free to ignore.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on May 13, 2013, 03:27:47 AM
op, can u explain what u mean by, "silver therapies" and "living cell therapy"?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on May 14, 2013, 07:30:03 AM
here is few examples:
Erectile Dysfunction (http://livecelltreatment.com/http:/livecelltreatment.com/erectile-dysfunction)
http://living-cell-therapy.com

Edit: it is also calling "fresh cell therapy" - "live/living cell therapy".
More details: A doctor on how live-cell therapy works | Entertainment, News, The Philippine Star | philstar.com (http://www.philstar.com/entertainment/2012-09-01/844191/doctor-how-live-cell-therapy-works)




Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on May 29, 2013, 09:21:37 AM
quick update:

Today I got my second ultrasound, after 2 months: my situation is improving, there's no more scar tissue in the zones in which stem cells were injected with the big needle. I would say now I have 10-15% less scar tissue than before (just my opinion).
I have to do 2-3 treatments more to get a bigger improvement but I'm pretty confident.
To be honest I do not feel great changes in erection and bend reduction at the moment, but Im sure it will improve.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: damian on May 29, 2013, 10:07:02 AM
What does that "(just my opinion)" mean? Did your uro confirm that you have less scar tissue?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: damian on May 29, 2013, 10:12:17 AM
Sorry mate, that was rude from me. I'm happy for you and your GOOD news are very encouraging.

Is it just me thinking that some kind of traction would benefit with the combination of stem cells?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on May 29, 2013, 02:38:20 PM
He did not give me a %, He just told me I got some improvements for sure.
By comparing the two ultrasounds you can see the plaque (white coloured) with some black points inside (healthy tissue)
My opinion is that putting a needle inside the plaque gives benefits also if placebo is injected; this is why someone got results in xiaflex tests (I mean placebo) or after verapamil injections. Obviously injecting stem cell is much better than injecting nothing...
I believe traction has helped as well: my penis is clearly more elastic than before, and I gained 0.2cm after 200hours of use.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on May 29, 2013, 06:16:01 PM
yyy

Encouraging to read your posts.
Do you mean 0.2cm after 200hours traction?
I got 1.2cm after using VED for a few months.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on May 29, 2013, 07:55:46 PM
Same question as James, 0.2cm (2mm) is quite small !
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on May 29, 2013, 08:12:47 PM
For me 0.2cm is better than nothing, and maybe its more, not easy to measure with a bend

With VED I got 0.0cm after a few months...
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on May 29, 2013, 08:14:56 PM
No problem, and very excited to see your scar tissue improving.  I hope things continue to get better before the next stem cell treatment !
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on May 29, 2013, 10:28:40 PM
yyy, do u mean to say that the stem cells helped u or the prp?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on May 30, 2013, 06:10:34 AM

stem cells
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on June 02, 2013, 11:41:15 PM
unfortunately, stem cells dont really work well in regenerating penile tissue.. weird that it works well in rats but not humans.

yyy, i got 2 questions...

1) did u ever get any prp injections?

2) have u ever experienced any hour glass around ur penis?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on June 03, 2013, 12:51:52 PM
actually Im getting some regeneration...

1) No, next step will be PRP or stem cells again, but my urologist told me that stem cells can be 10times superior than PRP

2) I have a shrinkage in the zone of the plaque, seems to be reduced after the treatment but it's not easy to detect the difference naked-eye.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on June 03, 2013, 01:02:51 PM
Sorry..
But YYY after the cure the plaque is restricted?
Aslo...i have seen that you are italian...when you done the treatment with staminal cell?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on June 04, 2013, 08:05:05 PM
yyy, 3 more questions:

1 - u said u'll get stem cells next.. when will u?

2 - ur doc said that stem cells are 10x better than prp. this doesnt sound accurate according to current research and experience. did ur doc explain this in depth?

3 - where are u getting this treatment? i'd appreciate it if u provide phone number and email.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on June 05, 2013, 06:06:01 PM
Today I spoke with my urologist again, asking him some deep questions:

By comparing the two ultrasound he saw some little improvements; Next step will be some PRP injection and not Stem Cells again: this because I still have many stem cells around/in the plaque but they need to be activated. He thinks that PRP can help with that.
About his details, I should ask him before putting them on the web, and to be honest I'm not sure he speaks English :D
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on June 05, 2013, 07:37:39 PM
koolx

Just a proposal:
Invest a little bit more time when you are writing a post that also not native English speaking and sms writers can understand your posts :)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on June 05, 2013, 09:48:00 PM
I agree with James,  YYY has been very generous sharing his info with us and I thank him for that. Gratzie !
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on June 08, 2013, 02:25:58 PM
james,

i dont understand your comment. are u asking me to write my posts clearer so non-english speakers can nunderstand me better? if this is so, i can try. i will re-post my questions to yyy. i see we have many spanish and french speakers on this forum.


yyy, here are my questions in a clearer way:

1 - did your doctor tell u why prp is 10 times stronger than stem cells?

2 - what clinic will u get prp from? provide contact info.


hopefully this can help non-englsih speakers so they can understand better. if something isnt clear, ask me to re-clarify.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on June 08, 2013, 04:39:01 PM
Koolx

Many on the forum are not native English speakers so sometimes shortenings that native English speaker are are using when sms or emailing each other are difficult to understand for us.
Like:
u = you
u'r = your or yours
etc'
Don't need to correct your posts, just for the future :)   

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on June 08, 2013, 08:37:20 PM
Koolx indeed i think that YYY said that stam cell are 10x+ better than PRP
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on June 10, 2013, 03:00:18 PM
james,
yes, youre right.. i will pay more attention to your suggestion. thank you.


Lollaro,
thanks.. i know yyy said stem cells are 10x better than prp. in theory thats true. but in actual practice, prp has shown to be far more effective than stem cells. stem cells have only shown minimal improvement.

also, he said that theres no need for more stem cells since the stem cells he got the last time are still around his plaque.. from what i have been informed, stem cells usually migrate out of the penis fairly rapidly after injection. i hope i'm wrong in his case. i'm a bit concerned that he may be misled. i wouldnt want that for anyone.


yyy,
please be careful if youre going to the Stamina Foundation in italy. the government almost shut it down. its under close watch now. if not, please let me know which stem cell clinic youre going to so that i can enquire about its treatment program. thank you.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on June 10, 2013, 03:49:28 PM
Koolx, I know you are not a fan of the Italian medical system :), but YYY is doing well with his treatment, so likely he is in good hands.  And If I were him I would not push the doctor to demonstrate proof that stem cell is 10x better than PRP.  If a doctor's treatment is helping me, no further scientific evidence is needed . And it is essential guys like YYY continue to update us on their progress.  As you know, there is no 100% cure for peyronies, so we do the best we can with the few options that are available. 

You likely agree at some point each of us has to choose a solution and stick with it maintaining faith and a positive attitude to obtain the best outcome.  If it is not successful you can always adopt a new strategy later.

Also, are you aware there are stem cell clinics here in the US ?  You might be more comfortable receiving treatment closer to home. Best of luck
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on June 10, 2013, 04:46:58 PM
funnyfarm, i think yyy is the best person that can tell us about his health since youre not him. and if he were fine, i dont think he'd be getting a 2nd round of treatment.

can u stop misinterpreting what people say. i never asked that he insist his doc to prove that stem cells are 10x better than prp. and if a doc is making a bold claim, the smart thing to do is to enquire, not let a doc do as he pleases. being complacent and not asking questions is ignorant. if i read or hear something that doesnt make sense, i speak up. i dont stay quiet and pretend everything is ok. if thats not how you operate, thats your life. i follow a different approach.

i'd appreciate it if you can stop answering people's questions for others. let others ask what they want without representing others since youre not that person and dont know whats going on in their lives. let yyy answer our questions and see what he says. if not, then there are other threads you can participate in. we're all trying to get the best health.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on June 10, 2013, 05:12:13 PM
Hi dear friends. :)
Everybody try to cool down and be less sensitive. :-[
Myself has to do that also from time to time. 8)
We are in the same boat on rough waters so better we work together. :-*

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on June 10, 2013, 07:49:39 PM
 I think that with staminal cells there is much to do...probably in few years will be found a cure that will cure the Peyronies al 100%(seems impossible,but i'm convinced that will be so)... Now there is only to experiment...unforunately
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on June 10, 2013, 07:54:32 PM
I hope you are correct Lollaro ! I don't see any other treatments as promising on the horizon.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on June 11, 2013, 07:39:07 AM
Koolx,

Thank you for worrying about me  :D
This is one of the doctors who offers the treatment:

Stem cell treatment for lichen sclerosus (http://lichensclerosus.org/italian-stem-cell-treatment/)

New Surgical Approach to Lichen Sclerosus of the Vulva: The... : Plastic and Reconstructive Surgery (http://journals.lww.com/plasreconsurg/Fulltext/2010/10000/New_Surgical_Approach_to_Lichen_Sclerosus_of_the.73.aspx)

New surgical approach to lichen sclerosu... [Plast Reconstr Surg. 2010] - PubMed - NCBI (http://www.ncbi.nlm.nih.gov/pubmed/20885230)


In this case it's a different desease but you can see He's not an improvised doctor, people come from all Europe to get the treatment.

About stem cells, I always knew that you need several months to get a complete healing and evolution, someone here such as rd can confirm it.
I had my plaque puntured in 3 points, and after the last ultrasound you can see some healthy tissue around those holes formed by the needle. My plaque is quite big so just a part of that was treated.
I repeat that now he wants to try PRP because it has a similar result of Stem cell (lower but similar) but it speed up the healing of the tissue and help to activate stem cells.
Please explain how they can migrate after being injected.....
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on June 11, 2013, 12:02:50 PM
I can confirm that it wasn't until 2-3 months after the initial treatment one of my plaques completely disappeared. Then another just shy of a year from the date of treatment. I would love to get another treatment but just can't afford it at this time. My plaques still seem to change so I also still hold out hope they may vanish with no further treatment.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on June 11, 2013, 03:12:33 PM
That is very exciting RD !

Unlike a pharmaceutical agent, I think the stems cells allow the body to heal as nature intended. It just gives you a needed boost, but like many good things in life requires adequate time and patience.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on June 11, 2013, 07:53:47 PM
yyy,

i appreciate the lnks. i've talked to some docs who said that stem cells for peyronies (generally but not always) takes 3 months - 1 year for some healing to be made. in general, 3 months is the generally accepted time frame for noticeable healing.

ED is tricky also. stem cells havent been able to restore complete erectile function. whatever positive effects have been realized were minimal at best unfortunately. but more is being done to improve the technology.

believe it or not, prp has shown to be far more effective in combating ED and peyronies.

i will post a link of the problems with stem cells migrating around the body when i have more time.


rd,
i assume that you had prp done that got you good results?


also, has anyone heard from rellisacct? i havent seen him here in a while.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on June 11, 2013, 10:29:27 PM
koolx

rellisacct was on line yesterday.
You may send him a PM if you have some question

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on June 12, 2013, 02:23:36 PM
Hey All,

I'm still around, just been really busy lately. I go back to Wake Forest next week for a follow up and further injections, so we'll see how things go. For some reason, the tissue near the first injections I had have tightened up a little again, but nowhere near where it was prior to injection. I can definitely tell that erections are harder and more pleasurable. I think that things have leveled off and I can tell that this improvement is permanent.

I'm hoping that further injections will just continue to increase tissue growth and start linking up blood vessels to improve blood flow. If this is the case, after a few more injections, I hope to start seeing some significant improvement. I'll give an update next week as things progress.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on June 12, 2013, 05:54:30 PM
Rellisacct

Good to hear about your progress.
Take your time, just update us if have something new. :)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on June 12, 2013, 06:34:24 PM
Koolx, no prp. I only had stem cells done. They did not offer prp with the treatment I had.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on June 12, 2013, 08:56:03 PM
Rd / Rellis  thank you so much for the updates guys !  This thread gets a huge number of views, so I am sure I speak for many others as well. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on June 13, 2013, 01:07:58 AM
Rellisacct,

did u get me pm's? i sent u like 3 so far..  but i never got a response from u. any reason why u failed to respond?


rd,

so.i.imagine that the stem cell treatment u got didnt give u good results.. will u consider prp next as a better alternative?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: damian on June 13, 2013, 02:58:59 AM
rd
did your plaques really disappear? I mean has your uro confirmed that or are they only not palpable anymore and what did it to your deformations?
Thanks


PS.: it would be nice to write down your experience with your stem-cell treatment in one post. It is a pain to seek through these pages to find your posts and puzzle it together.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on June 13, 2013, 06:59:01 AM
the_uphtipack, The uro's were no help at all. They all were arrogant peace's of crap that brushed me off(Sorry for my language). The reason I know my plaques disappeared is because I could no longer find them upon examining myself and because the deformation where they were located went away. I have other plaques I have developed in other areas that I would like to have treated as well and I would if I had the money. 1 year after stem cell treatment I had three plaques disappear two on the right and one on the left upper part of the shaft. The two on the right were the ones treated and the one on the left also went away after treatment, but was not treated because I did not have that one at the time of treatment. I have 3 small plaques that have developed since down closer to the base of my penis. The others were all up near the head. My plaques also ever since getting this condition have always seems to be in a state of change. I don't know if this is part of the reason why the others resolved after treatment or not. I don't think I ever had scaring only inflammation because I can't imagine scar tissue would change size and shape and go from hard to soft to hard etc.  I have also summarized in more than one post my experience with stem cell treatment as I have found people asking the same questions of me over and over. I also posted updates as they happened. To make life easier you could always search my name and have all post from me show up. I don't post often so only a few would not be related to the treatment.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: damian on June 13, 2013, 07:22:27 AM
Thank you rd.

Yeah, and no one seem to know the real difference between inflammation, scar tissue and plaque.

I hope you can afford another treatment in the near future or better it will heal from the first treatment in time.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: egghead on June 13, 2013, 09:58:34 AM
Is this treatment available anywhere in the northeast US? I've contacted a  men's sexual health center here and was told they don't do it.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: damian on June 13, 2013, 11:07:23 AM
I think it's still experimental, but costs like a real treatment.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on June 13, 2013, 12:45:42 PM
egghead, I had mine done in California but they have also started branching out and have a network of doctors all over the us that I believe use the same procedure. My reason for doing in Cali was because Dr. Landers is a Urologist which I don't think the other doctors in the network are. Also when I went to have it done they didn't not have a network of doctors.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on June 19, 2013, 09:25:48 AM
This morning I had a prp injection done.
The goal is to improve healing and vascularization of the zone (pretty bad at the moment)
Speak soon
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on June 19, 2013, 09:57:14 AM
Hey guys, quick update along with YYY...

The doctor I am seeing had some sort of emergency surgery so the next appointment and series of injections got pushed back to next week. I'll update soon...



Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on June 19, 2013, 09:36:59 PM
Thanks for the updates guys, we are eager to hear from you soon again.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Amitr on July 16, 2013, 04:23:27 PM
I just read about stem cell therapy online and I thought I'd share it here... but whoa.. there's loads of info about it here already.

So I have a few questions:
1. Since this seems such a promising new avenue (seems better than Xiaflex for one), shouldn't stem cells be popularized as a possible solution much more here.

2. We're more of a resource for clinical trials right here, so is there any way to get the medical community more aware of this forum. The knowledge of such a large readymade user base might be encouraging for an underreported disease and emphasize the need and viability of research.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on July 16, 2013, 08:31:33 PM
It is more of a political/economic issue.  Xiaflex has billions of dollars behind it, while Stem Cell just has a few clinics with innovative doctors who are willing to go beyond conventional standards.  In other words even if stem cell works great, there are no big corporations backing it, and no huge windfall profits for investors and governments. 

SS is more invasive, time consuming, and not patentable so I doubt it will be widely adopted even if it is very effective as it is less profitable.   

Hopefully there will continue to be enough people backing stem cell though to make it more widespread.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on July 18, 2013, 11:33:44 PM
funnyfarm,

thats not entirely true. big corps like merck, bristol-myers squibb, etc. are actively getting into stem cells for patent and licensing purposes. and they make it an effort to prevent good stem cell treatments from making it to the public. unless it produces a profit for them. 

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on July 19, 2013, 03:14:04 PM
Guys,

Stem Cells are potentially the most devastating resources that ever existed to the pharmaceutical companies because of the massive potential to heal and improve any medical condition.

The last thing pfizer or any of the other big pharma's want is to see their profit margins drop because stem cells are actually curing the disorder rather than deal with the symptoms.

I found a doctor in the area who does the stem cell procedure but the cost is $4,500 so at this time I can't afford it but I will be working towards getting enough money together to make it happen.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on July 19, 2013, 04:22:34 PM
I agree with MattFoley. Big pharma doesn't care about people's health, just the bottom line.

Can you disclose the name of that doctor Matt and where he is located?

Also, I'm going back to Wake Forest Tuesday for my second round of injections of PRP. I'll give an update ASAP.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on July 19, 2013, 05:02:27 PM
What is really novel about SS is that it gets to the root cause of the problem by inducing your body to heal itself.  Most pharmaceuticals on the other hand treat the symptoms, not the disease, so you never really get better and become a lifelong customer.  Koolx, I think it is quite plausible big pharma will try to develop and license SS.  This is not with the intention of helping patients, but rather to control the intellectual property, ensuring it is kept out of the mainstream, protecting conventional drug sales.   

I know there are herbals that are effective for cancer treatment, but you can not use them in the US because the FDA was convinced by these corporations they are not safe (based on studies where rats were given doses 1000' s of time higher than the therapeutic range).  So Americans are forced to rely on expensive chemo and radiation treatments alone, while enduring all of the barbaric side effects.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: inkhorn on July 19, 2013, 09:02:08 PM
Very interesting thread. I agree that it may not happen to most of us in our lifetime, but the research on stem cells is golden. I believe in it enough to pay to have my four grandsons cord blood collected at the time of their births. If this cussed disease has any genetic connection they will be set up for victory! Regards Inkhorn
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on July 20, 2013, 12:30:56 PM
rellisacct,

The doctor is located in southern California.

Here's the doctor's info:

Elliot Lander, M.D., F.A.C.S.
Medical Director
California Stem Cell Treatment Center

website: http://www.landerurology.com/index.html (http://www.landerurology.com/index.html)


Here's the website to the network of doctors across the country:

http://www.stemcellrevolution.com/ (http://www.stemcellrevolution.com/)


Good luck to you.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on July 21, 2013, 06:58:27 PM
hey Matt,

do u have erecrtile dysfunction or peyronies?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on July 23, 2013, 03:35:27 PM
Hey All,

Just thought I would give you a quick update from the doctors office.

This time they have taken double the amount of blood which equals double the amount of PRP. I'm thinking that they will inject all along the left corporal tissue as this is where the girth loss is.

More updates coming...
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: CTS on July 23, 2013, 08:54:16 PM
Hi all,

I talked to Dr. Elliot Lander at the California Stem Cell Treatment Center.

He aid he previously treated 12 patients with stem cells and  PRP.  In 50% of patients, he found no improvement and in the other 50% of patients he had a small  improvement. This was not good enough so he has moved on to try new proceedures.

He has now modified the proceedure to use shock wave therarpy and stem cells (and no PRP). You go for three sessions over 5 days.
- Day one, shock wave therapy.
- Day three, harvest adipose stem cells, shock wave therapy and inject stem cells.
- Day five, shock wave therapy

According to Dr. Lander, the shock wave therapy will be done all over your penis with focused treatment on the plague.  The stem cells will be injected into numerous locations in the plague.  The stem cells will hopefully cause healthy tissue replace the tissue damaged by the injections and shock wave therapy.  The shock wave therapy excite/wake up the stem cells.  Since your penis is basically a big blood vessel, the stem cells will start to move away from your penis in about two days and go to lymph nodes, etc. until they are needed again. He claims significantly better results with the three patients treated so far and just treated a forth patient with the new proceedure. The procedure costs $7,500. He admits it is experimental and cannot promise anything - of course. He thinks my Peyronies Disease is still somewhat active since I am still feeling pain, and that the stem cells may be more effective - and are less effective once the Peyronies Disease is in the chronic phase.

About me, my Peyronies Disease is now mild compared to many of others in this forum. My conditon started in summer of 2010 (six months after I got separated - talk about timing) where I initially could not even maintain an erection and then it improved somewhat to the current situation.
- current age is 44 years old
- some pain still on the left side
- only a 5 to 10 degree curve and 5 degree twist/rotation when erect
- lost about 1/2" in length and some girth
- erections at 80% of the past
          - I need fairly constant stimulation to stay erect
          - I can still loose one easily but that probably more perfance anxiety than anything
- talk the following every day
          - prescription grade anti-inflammatory to keep pain away
          - daily dose Cialis
          - pentox

My girlfriend says she is very satisfied with our sex life.  I think it is really more about me and the initial shock that has me thinking about the proceedure.

I could go for the Xiaflex treatment with my regular urologist in September 2013.  I wonder if I do the stem cell / shock wave or the Xiaflex?

Any suggestions on how I should proceed?

Thanks!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on July 23, 2013, 09:12:24 PM
Thank you for the update.  Dr Lander has some great credentials.  I see he is chief of urology at one hospital and chief of surgery at another, and also was a urology professor.   I am curious if he discussed any other Peyronies Disease treatment with you that might help in addition to SS/shockwave ?  And did you actually meet with him or just call, in other words are you a patient of his ?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: CTS on July 23, 2013, 10:12:04 PM
Hi Funnyfarm

We birefly discussed Xiaflex where he stated the goal of Xiaflex is to break down the scar (but it also breaks down healthy) tissue and grows back with normal scar tissue as oppose to excessive scar tissue as in Peyronies Disease.  He said no to do the Xiaflex and stem cells together. He pretty much did not have much to say about anything else.  He said the Pentox and Cialis do not help much...

He said he has seen many Peyronies Disease patients and can identifty plagues so he can easily target them for treatment.

CTS
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on July 24, 2013, 07:30:44 PM
Quote from: koolx on July 21, 2013, 06:58:27 PM
hey Matt,

do u have erecrtile dysfunction or peyronies?


koolx:

I have ED as a result of the Peyronie's. The blood flows into my penis but because of the venous leakage, it won't stay in.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on July 24, 2013, 11:12:59 PM
Matt,

what treatment options are u considering?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on July 25, 2013, 10:10:27 PM
Dr. Lue has me on VED therapy and as well as Pentox.

If I had the $4,500, I would definitely do the stem cell treatment with the platelet rich plasma therapy added to it.

I've been doing periodic traction and I'm also on testosterone replacement therapy.

There are other things I'm doing as well. I talk about it here: https://www.peyroniesforum.net/index.php/topic,3052.msg47106.html#msg47106 (https://www.peyroniesforum.net/index.php/topic,3052.msg47106.html#msg47106)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on July 30, 2013, 02:36:26 PM
Quick update 40 days after my last PRP injection

Erections are definitively improved, finally I can get a full erection when I need to get it, without meds of course.

I don't know if this is a permanent situation or just a temporary one, hope the former.

My Bend has not improved at all, libido has increased a little bit but not so much

I will certainly repeat the treatment, maybe together with my second stem cell
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on July 31, 2013, 07:45:47 PM
yyy how much is reduced the plaque?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on August 01, 2013, 04:54:47 PM
I believe it has not decreased at all or very little
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on August 01, 2013, 05:17:39 PM
yyy,

how long after getting PRP did u notice that u can get full erections?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on August 01, 2013, 08:59:27 PM
after about 20-30 days, hope this will be permanent
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on August 01, 2013, 09:17:22 PM
How do you to say that it's not diminished if you have a full erection? YYY
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Amitr on August 02, 2013, 11:26:18 AM
Quote from: funnyfarm on July 19, 2013, 05:02:27 PM
What is really novel about SS is that it gets to the root cause of the problem by inducing your body to heal itself.  Most pharmaceuticals on the other hand treat the symptoms, not the disease, so you never really get better and become a lifelong customer.  Koolx, I think it is quite plausible big pharma will try to develop and license SS.  This is not with the intention of helping patients, but rather to control the intellectual property, ensuring it is kept out of the mainstream, protecting conventional drug sales.   

So true. I just want stem cells to help me get back my life. The pharma industry should be tried for its crimes against humanity.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on August 05, 2013, 09:56:55 PM
yyy,

did the doctor advise u not to have sex for a week after he injected PRP?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on August 06, 2013, 01:25:45 AM
no... but I think it's just a sort of precaution in order to avoid any kind of injury during that healing period.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on August 06, 2013, 09:54:26 AM
YYY,

Based on what my doctor told me when getting the PRP (and some logical deductive reasoning), we should try to limit as much as possible the erections that we get for atleast a week. If there's a lot of blood flow after the injections, then it will wash the PRP out before it has a chance to settle and start signaling tissue to rebuild. This may be the same with stem cells too, but I know definitely for PRP.

Quick update: It has been 2 weeks since my last series of PRP injections and along with 5mg daily Cialis, erections are become rock hard again about 40% of the time. This is absolutely amazing as I was at the point where I would have 0% rock hard erections, ever. The main issue that I have left is the girth shrinkage due to the scarring and I've lost about 1/2 inch in length, but there is progress being made. There is still a long road to travel, however.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: funnyfarm on August 06, 2013, 02:50:14 PM
It is great to see you are making this fantastic progress !
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on August 06, 2013, 04:39:12 PM
rellisacct,

i hope u received the links i sent u.. and that thryll give u some info to work with. if u need more info, let me know.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on August 06, 2013, 05:48:30 PM
Hey koolx,

I looked through them and I'm extremely interested in the ACell one that you sent me. Have you ever seen the picture of where they regrew the soldier's leg muscle after half of it had been blown off? It is nothing less than phenomenal. If they can regrow fingertips and that much leg muscle, then our issue should be able to be improved.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on August 06, 2013, 06:06:07 PM
You are right rellisacct!!!
The difference is that while the regrow of the blown off muscle of the soldier it makes big waves and fame on the TV and other media.
Big advertisement!!! 8)
Growing back some part of a penis? No one will talk about it except if it was cut by someone girlfriend or wife. :(

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on August 07, 2013, 10:20:12 AM
Yes, unfortunately you are correct James. It seems that no matter what treatments they start coming out with, we always come full circle to the original issue which is lack of care/funding.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on August 09, 2013, 06:38:34 PM
hey, rellisacct..

i couldve sworn that i posted links here yesterday to the company making Acell and to the doc responsible for creating it. it may have been a computer error. anyway, here are the links. the doc's name is albert melman, btw:

this is dr. albert melman's contact info and website:
http://www.drarnoldmelman.com/contact-us/

the company founded by dr. melman that supports maxi-k:
Ion Channel - Gene Transfer Therapy (http://www.ionchannelinnovations.com/news.html)

recently, i emailed dr. melman and got back this reply:
"I wish I could help you. We need to raise to capital to move ahead with the ED trial. Keep checking our website when that occurs it will be listed there and on clinical trials.gov"

my thought on this is, i understand that trials are expensive. sometimes on a corp level. but, given that this is a M-A-J-O-R breakthrough therapy, why arent private investors, companies or med universities jumping immediately at the chance of investing in this therapy with potential future dividends? something doesnt smell right with his reply, IMHO.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on August 10, 2013, 04:46:07 PM
Koolx

I was not jumping to conclusions regarding
Quoteprivate investors, companies or med universities
not joining the project. It may be again not enough fame and not enough future money because the treatment will take long time to be approved.
We had sen other researches going this way (like stem cells).
Surprising me that Dr. Melman didn't propose you the treatment for a fee. Maybe if you had an appointment with him he was ready to make the treatment.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on August 13, 2013, 09:37:15 AM
I hope that they find a cure that resolve the peyronies desease to 100%..

Many like me are young...and they hope in a definitive cure...
Unfortunately, the disease is not widespread and there are many researchs for lack of founds
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on August 14, 2013, 09:38:38 PM
lollaro,

autologuos stem cell and prp therapies seem to be doing an excellent job so far in reducing peyronies.. look into these treatment options but make sure that u find a reputable clinic.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Craig on August 22, 2013, 02:30:24 AM
Do autologuous stem cell and PRP therapies work for those in the chronic phase? I know Xiaflex disolves actual scar tissue, giving people like me in the chronic phase hope.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on August 22, 2013, 09:47:15 AM
Craig,

I've had this crap for 11 years so it's pretty safe to say that there are calcified plaques. The PRP has helped me to at least get an erection again, but I don't think that its actually dissolved any of the plaque, maybe just re-shaped it. I'm still at the point however that if future PRP & Stem Cell injections don't loosen the scarring, then an implant will be the only option. The erections are still just not ridgid enough for prolonged sex. I've gone too long now without satisfying erections and can't wait for the rest of my life on "hopeful" remedies.

The reason I say this is that PRP won't be a "cure", but it might be helpful for people who have less scarring in their penis than I do (a single location rather than all over).
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: jackp on August 22, 2013, 07:26:21 PM
ewllisacct

Quote from: rellisacct on August 22, 2013, 09:47:15 AMThe erections are still just not rigid enough for prolonged sex. I've gone too long now without satisfying erections and can't wait for the rest of my life on "hopeful" remedies.

Some who just glance at my story think I went straight to an implant. I also waited about 2 years after an implant was suggested before I considered it.  Kept trying everything possible short of an implant. My implant was almost 5 years ago. I wish I had it years earlier. You talk about satisfying erections an implant will give you that and more. I'm almost 71 now and within 30 seconds I can have an erection that sticks straight out, last as long as I or my wife wants, as many times a month as we want. NO I was wrong my wife and I don't just have sex, we make love! The feelings of making love to my beautiful green eyed wife are amazing.

If you have any questions about implants just send me a PM or email. I have some information you might like to see.

Jackp
http://jackp-penileimplant.blogspot.com
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on August 23, 2013, 09:50:52 AM
Thanks Jack,

I'm becoming more and more convinced that an implant is the correct option for me, but I guess for my own personal satisfaction I want to be able to say that I exhausted every other option available before going forward with it. My decision would be much easier if I couldn't an erection at all, but the erections I get are not good enough for sex so I guess it's just as bad as not having one.

I am planning on going to Dr. Milam around October for an initial consultation as you and a few others have spoken highly of him. But before I have surgery, I am going to go back on a VED protocol for 2-3 months and at least try the stem cell injections. Who knows, they may just work. If not, then there will atleast be finality to my sex life vs living in limbo all the time.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: damian on August 23, 2013, 10:16:39 AM
There is another thread about implants. I'm always thinking there are news about stem cells, everytime I see somebody posted here.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on August 23, 2013, 12:43:27 PM
Yes Ushtipack, usually it is. The implant was a "one off" item. I was simply stating that PRP most likely won't cure anybody, but can definitely help if the plaque/scarring is localized. Additionally, I said that I will be getting stem cell injections when I can get time off of work to get it done. Both are relevant to the topic at hand.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Derick on August 26, 2013, 04:07:58 PM
So, does the stem cell therapy do any good for venous leakage? Does anyone have any experience with it helping venous leakage and/or Peyronie's? ... and what would preclude a number of us to form our own 'group' for treatment with the stem cells.. (50... 100?)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on August 26, 2013, 04:50:11 PM
Hey riladojr,

I see from a previous post that you are in SC. I go to Dr. Terlecki in Winston-Salem which is about an hour north of Charlotte (where I currently live). He's good and I'm positive that he'll be able to help you.

Also, I think that the PRP has helped some with venous leakage because prior to receiving injections I couldn't even keep an erection. Now, I don't have as much trouble keeping it up, but it's just not usually a rigid erection due to scarring. What exactly are you recommending when you ask about a number of us forming our own "group"?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on August 26, 2013, 10:53:08 PM
rellisacct,

hey rellisacct.. how u doing? i got something that may help your particular situation and riladojr's. i came across info info on a dr. hsu. i think i suggested it to u before but i dont remember. his surgeries from what i've read have helped a lot of ED sufferers with venous leak and with "filling" the girth of their erections. u may want to take a look:

ED-Forum.com &bull; Information (http://www.ed-forum.com/viewtopic.php?f=13&t=111&sid=190fd71a3b1a9704e14c90c9c143f7a6&start=530)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on October 02, 2013, 11:56:04 AM
Hey guys, I just wanted to give a quick update on progress from my most recent PRP injections.

I had 2 injections Tuesday of last week at the base of the penis on the left side. This is where the bottleneck has been for 11 years and where there is calcified tunica on the top which gives an indention on the top of the penis. It appears that after 5 total injections so far, all in the left corporal tissue, the PRP has formed a matrix and is linking up blood vessels where scar tissue had taken over. I can now at least get an erection suitable for sex it appears. I think that the PRP is regenerating the corpus cavernosum in the penis by increasing blood vessels and smooth muscle, however, the tunica is scarred to the point where it's not letting the tissue expand to its pre-injury girth. I have increased about 1/4 inch in girth from injections alone, which I'm pumped about. It may not seem like a lot, but for me that's a major victory.

Considering where I was just 6 months ago to now, I have to say that I'm cautiously optimistic about the future for the first time in years. I have a few more PRP injections lined up and will update as things progress. I do want to add that this is not a cure by any stretch of the imagination and things will never be close to where they were pre-injury, but God willing I'll be able to at least feel human again.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on October 02, 2013, 02:49:04 PM
found this article, link below.. we're getting there, people:

Scientists create reprogrammable mouse in stem cell breakthrough, opening a new way to regenerate failing tissues in patients with diseases ranging from heart failure to diabetes | Bamboo Innovator (http://bambooinnovator.com/2013/09/12/scientists-create-reprogrammable-mouse-in-stem-cell-breakthrough-opening-a-new-way-to-regenerate-failing-tissues-in-patients-with-diseases-ranging-from-heart-failure-to-diabetes/)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on October 02, 2013, 08:30:02 PM
That's a good share!

P.S. rellisacct I'm happy for Your improvements!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on October 02, 2013, 10:31:22 PM
Thanks Op, we all have to just keep fighting. There are some amazing things that are going to happen in the next few years, I can feel it.

Nice article Koolx...another promising therapy for the future.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on October 03, 2013, 02:16:20 AM
rellisacct

Based on your results, you (and us) may be surprised in the future that your statement was too pessimistic :)
QuoteI do want to add that this is not a cure by any stretch of the imagination and things will never be close to where they were pre-injury
I think that having such improvement after 11 years with Peyronies is amazing :)
Thank you for sharing with us :)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Knight on October 03, 2013, 08:16:32 AM
It is refreshing to read about someone experiencing positive results! Congrats and thanks for sharing and spreading hope!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on October 04, 2013, 12:35:15 AM
The medical community is screwing with us. They KNOW what stem cells and PRP can do for us. They have the proof. Both of these treatments can help a multitude of ailments but at this point it's expensive and the blood-sucking insurance companies don't want to cover it. Doctors make more money from treating your symptoms rather than the cause.

I need to make more money so I can rescue my penis from this hell.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on October 04, 2013, 05:43:53 AM
Definitely on a surgery the doctors are making much more money!!!

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on October 04, 2013, 07:32:21 AM
hey dudes

Good news by my side!

I had an ultrasound before any treatment from a "third part" and today I repeated it, after 1 stem cells and 2 prp.
The result is that I'm improved!! longitudinal thickness of the plaque passed from 10mm to 7mm, but the rest is unchanged as well as the bend, still present. My erections actually improved a little, as well as elasticity.

I will get my 2nd stem cell in one month or so, I think after 2 of them I will get a significant tangible improvement

stay tuned!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: lukewill on October 04, 2013, 07:35:40 AM
YYY - do you mind me asking where are you getting treated?

best

luke
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on October 04, 2013, 08:20:02 AM
NOrth Italy, in a public hospital.

I prefer not to mention his name, I should ask him before.

If anyone is interested, I can ask him some details such as costs etc and I could organize some live consultations.

Im not sure but I think he does not speak English very well, in this case I will help him!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on October 04, 2013, 10:42:16 AM
MattFoley - I completely understand your frustration with the powers that be. It's like I've poured gasoline on my savings and watched it burn. Obviously PRP and stem cell injections are having a positive effect, so it would lead one to believe that insurance companies would start looking into covering them. I mean wouldn't it make more sense for an insurance company to pay for $5,000 of injections and get better results than pay for a $30,000 surgery with possible impotence and even more expense down the road? No matter, in my opinion, having a quality sex life with a functioning penis is far more important than having money, whether I pay for it or the insurance company does.

One more thing...I am blessed to live an hour away from one of the only urologists to my knowledge that is doing this type of treatment in America. If I didn't live so close, there's no way that I could afford flying in and out for multiple treatments. I know this isn't a religion forum, but I personally believe that God has led me to where I'm currently at for multiple reasons, which are easier to see now then when I was at my very lowest points. If I had never had a glimpse of hell while on earth, then I probably wouldn't have the faith that I do now.

YYY - We are all encouraged to hear about your improvements. Keep the good news coming!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on October 04, 2013, 04:25:00 PM
rellisacct

This forum is not a religious forum, but definitely not anti-religious also :)
For many of us, faith is what is keeping us going forward with this disease :)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: stopthismadness on October 09, 2013, 04:31:11 AM
Since there is more than one topic already open related to stem cells and tissue engineering, I'll post these here.
They are concerning Adipose Derived Stem Cells (ADSC) , Peyronies Disease, and improved erectile function. Dr. Tom Lue has also offered a response.
Basically, what I've gathered from reading is that they can potentially halt Peyronies Disease from progressing in an animal model.  More experiments are warranted to see if they can do anything about Peyronies Disease that has already progressed (which I believe most of us here can't wait to find out) It seems promising, and it's all worth the read to just be informed about where they're at. One step at a time.

Intratunical Injection of Human Adipose Tissuederived Stem Cells Prevents Fibrosis and Is Associated with Improved Erectile Function in a Rat Model of Peyronie's Disease - European Urology (http://europeanurology.com/article/S0302-2838%2812%2901102-5/fulltext)

Adipose-derived Stem Cells for the Treatment of Peyronie's Disease? - European Urology (http://europeanurology.com/article/S0302-2838%2812%2901326-7/fulltext)

Reply from Authors re: Ching-Shwun Lin, Tom F. Lue. Adipose-derived Stem Cells for the Treatment of Peyronie's Disease? Eur Urol 2013;63:5612 - European Urology (http://www.europeanurology.com/article/S0302-2838%2812%2901470-4/fulltext)

Scaffoldless tissue engineering of stem cell deriv... [J Sex Med. 2012] - PubMed - NCBI (http://www.ncbi.nlm.nih.gov/pubmed/22513032)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on October 10, 2013, 05:39:14 PM
stopthismadness, thanks for posting that info.

The huge cost of stem cell treatment is my biggest concern since there's not really the best data on how it will treat Peyronie's. Until the cost comes down or I hit the lotto, I'm going to have to look towards PRP and HGH and things like IGF-1, PEG MGF, and TB4.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on October 11, 2013, 04:57:47 PM
stopthismadness,

the problem with these studies is that it involves animal models. until we involve humans in a research model, theres no indication of whether or not they'll work in humans. just because animals respond well to stem cells doenst mean that humans will also. there are many drugs and therapies that work in a rat model but fail in a human.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on October 11, 2013, 10:15:47 PM
koolx, I think some people are experiencing success with stem cell treatment. The problem is that it's very expensive.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: stopthismadness on October 11, 2013, 10:17:05 PM
I'm aware of all of that. Everyone seems to be misunderstanding my intentions of posting and repeating "the problem with this is." I know the "problems", I'm not posting to say "Hey look here is a miracle cure, this is going to work!" That's just not going to happen, I'm posting to share information for those that are interested. They aren't just going to start experimenting on humans before they do it on animals, it would be inhumane and unethical. My intent is to show that they did something Peyronie's related with stem cells, of course they are going to use animals first.  I think it's great news that someone even focused on our problem to begin with, even if it's with animals. I figured it was important enough to warrant a share on here. Very, very early experimental studies to gather information to possibly help combat this. Whether it works or not is up for further study, which I eagerly await to happen. Hopefully next time they do this experiment it's to see if they can attenuate already established Peyronie's Disease rather than preventing. If they do, and it works in rats, it would look like damn good news to me, fingers crossed and maybe something clinical will eventually happen. This is all experimental science. I don't condone anyone going out and getting stem cells injected into them at any of these unregulated clinics, they have no idea what they'll differentiate into. A woman recently had stem cells injected above the eye in a Beverly Hills clinic and it differentiated into bone. They literally removed bone splints that had grown from her eye. Nature isn't that simple, injecting stem cells with no instructions given to what they differentiate into is taking a shot in the dark. On top of that, I've read elsewhere in another experiment that when stem cells are injected intracavernously into the penis they don't even stay there, they rapidly escape, so they may not even differentiate into any healthy penile tissue. This is all future speculative science, and right now, in my mind, that's all we've got going with this disease at this point, to wait for something to spring up in the future. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on October 11, 2013, 10:24:00 PM
stopthismadness, I completely agree and understand where you're coming from on this issue.

This forum is titled, "Developmental Drugs & Treatments". This is a good place to discuss exactly what you're talking about. Stem cell, PRP, PEG MGF, IGF-1, etc. are drugs that fall into this category and are valid for discussion. Ignoring these drugs would do a disservice to what we're trying to do here: Heal from Peyronie's.



Now for my disclaimer:

Please do not inject chemicals into your penis unless you know what you're doing. I'm crazy enough to do it but I urge others to wait until more data is available before doing anything. If I'm able to succeed in my attempts and remodel scarring, angiogenesis, etc., I will be happy to share my results for an appropriate fee.  :P
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on October 12, 2013, 02:46:25 AM
MattFoley,

absolutely! there have been very good responses from stem cells relating to peyronies. but we're still not out of the woods yet. the ultimate goal is not just to freeze the advance of ED and peyronies in their tracks but actually reverse them completely.


stopthismadness,

i think the early animal studies show great promise. but my point is that just because animals respond well to treatment doesnt necessarily mean that humans will follow the same path. for example, stem cells have been able to repair damage in smooth muscle and nerve tissue in the corpus cavernosum of the penis of rats stricken with ED. but in humans with ED, it just doesnt work as well; results are minimal at best as confirmed in a few studies. but i do agree with incredible certainty that ED and peyronies will be things of the past once we remove all or at least most of the kinks. unfortunately and realistically this realization will take time. the good thing is that we're getting there, especially when discoveries about stem cells are being made on a daily basis.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: stopthismadness on October 12, 2013, 03:24:25 AM
koolx, can you share these ED/stem cell studies done in actual humans? I can't seem to find any..
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on October 12, 2013, 05:47:40 AM
stopthismadness,

much of the human studies are actually patient-funded clinical trials that autologous stem cell clinics provide. theres one in california thats affiliated with a network of other stem cell clinics throughout the country offering this type of treatment for this condition as well as for others. theres another in florida (i think in miami but i dont remember) whose clinical trial for ED i believe ended a month ago.

the clinic located in california has been mentioned in this thread. the doctor of that clinic is dr. lander. i'll try to get the name of the other clinic in florida but u got to give me some time.

remember, when it comes to stem cells, these patient-funcded cllinical trials are rather expensive. and as rellisacct mentioned before, much of these undiluted therapies contain more stromal cells than actual stem cells. the FDA curently bans any SC clinic in the US from multiplying and administrering pure SCs in humans as i understand it.

looks like the FDA is protecting the pharmafia from draining its profits from autologous SC treatments which in many cases have saved lives and improved people's health in areas where conventional medicine has and continues to fail.

also, i think someone mentioned that SCs injected into the a target area within the penis will migrate to other parts of the body. this is ususually true. but, there currently is technology that uses an encapsulated mesh that keeps stem cells in place in a precise area of tissue for a longer period of time than would otherwise be the case in order to effect repair. theres a company that makes it specifically for SCs.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on November 08, 2013, 09:30:12 PM
I see no updates for a month. :) Decided to Google some, and found something new with PRP injection -Priapus Shot
here is several official websites:
http://www.eternamd.com/priapus-shot (http://www.eternamd.com/priapus-shot)
http://priapusshot.com/ (http://priapusshot.com/)
http://advancedlifeclinic.com/the-priapus-shot‎ (http://advancedlifeclinic.com/the-priapus-shot)

What I've noticed it is only available in United States at the moment & if I'm not missing something it is brand new cure or whatever else in PRP medical terms. personally I'm from Europe... but it still points me to be interested at the moment, so decided to share over here. maybe someone else knows a bit more about it.  Priapus Shot is claiming as tissues regeneration injection in the natural way.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: BentYoung on November 08, 2013, 10:55:24 PM
Op -

That medical video explanation is VERY interesting indeed. He literally explains exactly what a Peyronies sufferer needs: minimal inflammation, new blood vessels, additional blood flow and new collagen development. This is the patients own blood and plasma as well, so there is almost no chance of a bad reaction. Why does this sound way too good to be true?!! This is the video that you provided that I am referring to Vampire Facelift (R) and PRP Research Reviewed - YouTube (http://www.youtube.com/watch?v=GLVLOAJmGvg#t=651)

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on November 09, 2013, 09:37:59 AM
OK. So, I've done more research just yet.
The same reaction was for me too:"This is to good to be true"
The average price: 1800-1900$
Mostly the guys on internet talking and willing to gain length and girth, because it is called to make increase. (I do not need this, and wont hear about it anymore, that's how I made the damage for my self) and such facts quite pushing me off to believe that it is genuine information about the positive results from the injection.

The second part is, what make me to be interested: it claims to rejuvenate the penis, regenerate to more healthier, bring back firm, sensitiveness, pleasure. I do maybe believe it could be true, since I do remember a member over here reporting positive results from PRP.

p.s. as BentYoung mentioned Priapus shot not harmful and without risk for side effects. The results can be noticed after 3 weeks to 18 month

and I've found that a bit was already discussed over this forum about this priapus shot: https://www.peyroniesforum.net/index.php?topic=3885.0 (https://www.peyroniesforum.net/index.php?topic=3885.0)

This is very confusing for me. This is also called to be a cure for ED, but all these penis size increase blowing me off.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: damian on November 09, 2013, 11:24:39 AM
The length is different between an erection of 90% and one of 100%. I noticed a difference in 2-3 cm. When the glans isn't engorged, you might notice a "loss" of a cm and more too. Some guys here are talking about severe length loss, but cannot achieve an erection of 100%. I'm sure that many of this guys who claim to have ED, are under psychological pressure so the develop ED, and therefore "lenght loss". I was like this too. I thought I lost 3.5 cm and was under huge pressure, but then I measured a 100% morning wood erection and noticed a loss of 1 cm or less. So, my conclusion is : better erection = bigger penis, better erection = less curvature.

This therapy might work, but I do not believe that you get a bigger penis from it.
If you are on therapy that is promising, placebo effect might do the work and you'll get better erections and therefore a bigger penis. Just my thought.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on November 10, 2013, 11:40:52 PM
the_Ushtipack

I agree with you in 100%.
I would like just to add that many ED sufferers have venous leakages (like me) and in this case the erection will never be 100% except with VED. This is the reason I am measuring the length while doing VED. I have lost 6.5 cm to Peyronies, got back 1.5 cm using VED, Pentox, low dose Cialis and Ubiquinol. Got back some girth also. But still the maximum erect length is 13 cm and girth 60% from the girth before Peyronies (checked during VED).

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on November 19, 2013, 03:20:48 PM
op, this is mothing more than PRP. I called one of the clinics offering this priapus shot. and again, they tell me its just PRP. this is just a marketing name for PRP. Nothing new here.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Guztavo on November 27, 2013, 04:04:57 PM
Guys, just wanted to let everyone know that i've been through the treatment in the California Stem Cell Center with DR Lander.

Dr Lander seems very nice and all of his staff seem very professional. I had to be there for 1 week and had liposuction, then the stem cells injected into my penis, and also shockwave therapy.

So far it's been only 1 week so zero results, but expect to get some feedback (wether it worked or not), by three months max.

You can send me private message here if you have any questions since i don't always check the forum.

Cheers
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on November 27, 2013, 04:40:55 PM
Guztavo

Thanks for the update, I hope you will not forget to update us at the 3 months milestone.  :)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on December 01, 2013, 06:16:50 AM
hey gustavo,

hope everything works out.. think positive! and like the poster above me said, please keep us informed as to your progress. all the best to you..
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on December 01, 2013, 09:56:24 AM
Gustavo,

Your experience sound similar to mine but I only had to be there one day as he wasn't using the shockwave therapy at the time of my procedure. Was this only stem cells and shockwave therapy did he use any PRP/ Just curious as to the differences between what you had and I had.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on December 03, 2013, 03:19:35 AM
Quoteop, this is mothing more than PRP. I called one of the clinics offering this priapus shot. and again, they tell me its just PRP. this is just a marketing name for PRP. Nothing new here.

koolx, did you ask the Priapus Shot doctors and the PRP shot doctors about the site injections? The doctors doing the Priapus Shots inject in the glan whereas the PRP doctors do not. There is some difference in the technique and that could mean the difference in the outcome.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Guztavo on December 03, 2013, 03:45:30 PM
@rd he did shockwave for a couple days before treatment, then they did lipo and stem cell injection on the same day. Since i happened to be staying in town for one more extra day he decided to give me an extra shockwave session a day after stem cell, but this last one was not planned.

I had the treatment november 20th, so far everything is the same as always, so no visible improvement, but it's been only 2 weeks so no conclusions until the three month mark, which is the timeframe he mentioned.

Will keep you updated.

@rd how long ago did you get the treatment and what was your final conclusion about it?

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on December 06, 2013, 02:44:52 PM
I had it about two years ago. I had one big lump on the right side of my shaft that was always changing sometimes it felt like 2-3 separate peaces. When I had the treatment it felt like 2 lumps. At about the 2-3 month range one was gone the other still remaining. I did end up developing another lump on the left side of my shaft not a big one just a small one and also had the remaining lump on the right side. So I'm not sure what to think. One of the lumps on the right was gone after 2-3 months so it appears to have had some effect but I developed another on the opposite side which wasn't treated. My lumps always seem to be changing as well. Sometimes feeling as though they are on the verge of going away. I do have to say that since treatment my pains have faded to the point of pretty much being none existent. I think I have a very mild case as I have only had lumps that cause dents no shrinkage that I can tell or curving.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on December 12, 2013, 02:01:23 PM
Quote from: koolx on November 19, 2013, 03:20:48 PM
op, this is mothing more than PRP. I called one of the clinics offering this priapus shot. and again, they tell me its just PRP. this is just a marketing name for PRP. Nothing new here.

Ok. thanks!

Quote from: MattFoley on December 03, 2013, 03:19:35 AM


koolx, did you ask the Priapus Shot doctors and the PRP shot doctors about the site injections? The doctors doing the Priapus Shots inject in the glan whereas the PRP doctors do not. There is some difference in the technique and that could mean the difference in the outcome.

So, priapus Shot is not simple PRP. Thanks! :)

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: jnbarizona on December 12, 2013, 11:51:36 PM
Hello everyone. I want jump into this thread and contribute to the conversation. I previously introduced myself in the appropriate thread recently. I've had Peyronies Disease & ED for 11 months, as the result of an injury. No vitamins or medications have worked. At the end of my rope, I stumbled upon stem cell trials going on in CA, and I'm going forward with the procedure. Anyone who has been following this thread is familiar with Dr. Lander. I will be getting the week long treatment next week(shock wave Monday, Lipo + Stem Cells + shock on Wednesday, shock again on Friday). Luckily for me, it was only a 4 hour drive. I've already paid the money, almost all of my savings, so I guess you could say I'm all in. I plan on updating here about the process, as well as the results as they come. We need more testimonials from Peyronies Disease sufferers who've done the stem cell therapy, and I intend to one of them. I think this is the best hope we have at the moment.

One last note about medications(I'm not trying to switch topics, just thought this is worth sharing) to everyone out there who is using the Pentox... I asked Dr. Lander if I was wasting my money on it, his answer in print was a definitive 'yes'.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on December 13, 2013, 01:14:38 AM
op:

QuoteSo, priapus Shot is not simple PRP. Thanks!

Exactly. There's a difference between not only injection site, but also technique, and the actual centrifuge used. And the Priapus Shot doctors also require that you use VED right after the injection and as part of a regular schedule. The PRP doctors do not.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Guztavo on December 13, 2013, 12:17:14 PM
jnbarizona

I had the treatment done 3 weeks ago. So far no improvement at all, but Dr Lander said it could take up to three months.

Good luck with your procedure and keep us posted!

Gustavo
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: e2219e on December 16, 2013, 09:16:32 PM
All,
I have been doing some amateur investigation on this topic over the course of the last several months as I sustained an injury that has lead to a greater curvature and erections that are more difficult to sustain.  Ironically, I came across an opportunity to become an independent rep with a company that sells a PRP device around the same time and, understanding a little about the possibilities in would healing, peyronie's came to mind immediately.  I actually sell a variety of medical devices, but the potential to solve my own condition is what got me involved. 
Since I haven't seen it anywhere on this post, I should mention there is a company called ................ that sells a biologic material used very successfully in peyronie's repair.  Go to ......................... to find the device.  I do not work for them, but know of some physicians who swear by it. The material is called ......................, and you should be able to search the site for Peyronie's, or contact their Urology division. 
PRP, in theory, delivers a high concentration of platelets, cells and growth factors that promote healing.  The ...................... material is a scaffold (another required part of healing) that also contains growth factors.  These growth factors call in cells required to repair damaged tissue.  Here is our issue - We need a treatment that will 1-  Break down the scarring that has occurred 2- deliver appropriate cells and growth factors to remodel healthy tissue (not scar) and 3- perhaps have a scaffold upon which the cells can organize.  I am not a scientist, but it seems to me the combination of all three would be ideal. 
The Priapus shot, or P-shot, is one of a few trademarked names for PRP injection procedures by the same doc that has the Vampire Lift.  I think it sounds promising, but am unaware of any serious data on the procedure.  Much of PRP use is theoretical, hence no medical coding or reimbursement, hence you pay cash.  I should say there is actually a code now for PRP in wound healing.  That is because this is were the best PRP data exists/  The reimbursement amount is $85.  This is new, and insignificant as a dollar amount, but at least it is being recognized as having real healing capability.  There are efforts to increase the reimbursement amount.
I have a lot more questions than answers.  I am going to be working on finding doctors interested in looking more closely, and scientifically, at PRP for Peyronie's.  I would be happy to try and find answers if you have questions.  This is a big issue, and I hope this forum can help lead to some solutions, or research.

Some changes has been made by moderator. It is your first post and it sounds like a marketing post. Hope it is not!!!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Mentos on December 16, 2013, 09:36:28 PM
E22 hope your really in our corner man and not just a rep. There is one person getting PRP soon on here I believe , hopefully we will learn a lot about it through him. And most importantly hopefully it does wonders for him!!

Please keep me up to date. I know mattfoley would be keen too.

Thanks and good luck with your search. Let me know of I can help.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: e2219e on December 16, 2013, 11:03:43 PM
Hey Mentos, I totally get the suspicion of reps.  That is why I wanted to be up front about it.  I am one, but have had far more success working toward improved patient outcomes than making another dollar.  And in this case, I have a personal stake in finding a solution to the problem.  I tried to stay away from opinions on anything, and will continue to do my best to talk science and evidence.  I am happy to direct you to any clinical evidence I know of if you have questions.  I cringe when I hear people putting faith in anything that is unproven out of, and I've felt it, desperation.  Still, someone needs to go first, and second, in order to find out if these new approaches have promise.  I wish those going for PRP treatment the best.  There is fantastic evidence for PRP in wound healing, just nothing in Peyronie's to date that I am aware of. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: shrout on January 30, 2014, 04:52:44 AM
Further progress in stem cell therapy...

http://www.bbc.co.uk/news/health-25917270 (http://www.bbc.co.uk/news/health-25917270)

Whether or not or how this might help treatments for Peyronie's in the future I'm not sure. But it's surely a positive development??
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on January 30, 2014, 06:16:24 PM
An other one:
Stem cell breakthrough may be simple, fast, cheap - CNN.com (http://edition.cnn.com/2014/01/29/health/stem-cell-discovery/index.html?hpt=hp_t3)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: shrout on January 31, 2014, 02:08:32 PM
That's a report on the same study, James. Good to have a different take on it though.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on January 31, 2014, 08:04:56 PM
You are right shrout. Just from a different source.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on February 03, 2014, 01:17:49 AM
shrout, stem cells are stem cells no matter what method is used to extract them from blood.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: shrout on February 03, 2014, 05:29:51 AM
Understood, koolx.

The 'breakthrough' here, if that's what it is, is in the innovative method they are using to obtain them, or in this case, create them. It has the potential to make the supply of stem cells cheaper faster and safer, which would surely make them more widely available for research into possible therapies for Peyronie's.

Are you saying that no progress has been made here?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on February 03, 2014, 06:08:23 PM
You are right shrout, the new method is the point her as you say:
Quote....supply of stem cells cheaper faster and safer

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on February 06, 2014, 11:17:31 AM
Hey All,

I know that it's been a long time since I last posted, and for that I apologize. I have been dealing with heavy depression lately due to another sexual trauma that I experienced 3-4 months ago due to penis not having enough rigidity.

This should be of interest to some folks on here. I have been working with a urologist/tissue engineer at Wake Forest and just went down to Mexico for a stem cell clinical trial. The first phase was liposuction of the abdomen to harvest adipose tissue (adipose derived stem cells), of which they received a lot of cells. So basically I'm getting a two for the price of one (sexier abs and stem cell injections, hard to beat that). I will be going back down in 6 weeks for injection after the doctors culture the cells into multiple lines and expand them. There is a special type of gel that the urologist will use to inject the stem cells into the corpora tissue, which he stated should keep the stem cells localized for a longer period of time and also this gel has increased growth factors. He has had some very good results from this procedure already, so I'm cautiously optimistic.   

This is significantly different than how stem cell injections are performed in the U.S. from what he tells me. I'll keep everyone updated as things progress. Additionally, if this doesn't work, then there is a strong possibility that in the near future he will be starting up a clinical trial for total corpora replacement (rabbit studies, but for humans). I'll give more information as things progress. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Mentos on February 06, 2014, 12:09:08 PM
Ressilect

Very interesting to hear about. I live in Cali and would be interested in taking part in this if possible. can you give me/us more info.. PS your inbox is full or else I would have msgd you.

THANKS AND GOOD LUCK!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on February 06, 2014, 12:11:34 PM
Oops, I just deleted some old messages. Yes, PM me and I'll tell you more about it. I will say that it is VERY expensive. I've spent a chunk of savings on the procedure so far.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Knight on February 06, 2014, 05:14:12 PM
Very interesting. When you say, "Very expensive" can you give us a clue?

Good luck!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on February 07, 2014, 10:02:07 AM
With lipo, culture of cells/growth factors, injection, hospital bills, travel for myself and doctor to and from Mexico...Final cost will be ~$15,000. So take your pick between a (hopefully) improved penis or a new car.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Knight on February 07, 2014, 06:40:58 PM
If it is successful it would be worth every cent. Please keep us posted!

Good luck!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Mentos on February 07, 2014, 08:12:52 PM
I choose renewed penis!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Guztavo on February 08, 2014, 06:26:51 PM
Hi Guys, just wanted to post an update as i promised.

I had the Stem Cell procedure with Dr Lander in California.

I am just 12 days shy of the 3 month deadline he mentioned to see results. Unfortunately, in my case, it didn't work. I have not seen any improvement whatsoever so far.
If anything changes i will let you know.

That said, not sure if it will be the case of everyone, i didn't have a plaque to start with just curvature, so he said he didn't have a "target". Also, i did feel they are serious and are looking for a legit cure for this, not a scam. However, in my case it didn't work.

Hope this information will be useful to others.

rellisacct please keep us posted on your progress, since what you describe seems slightly different to Dr Lander's procedure.

Cheers
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on February 08, 2014, 06:39:25 PM
Thanks for the update Guztavo.
Sorry it didn't worked for you, but maybe you will see improvements later. As I understand it can be up to 6 months to see if it really worked.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: muffslayer on February 09, 2014, 06:18:35 AM
I'd rather have peyronie's for the rest of my life, then support or use stem cell research.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: emasculated on February 09, 2014, 08:07:18 AM
Ahhh.. come on..
I'd rather harvest and EAT embryos for the rest of my life then spend one more second with Peyronies Disease. How's that? :-P
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on February 09, 2014, 12:01:21 PM
muffslayer, these stem cells are "NonEmbryonic". They have nothing to do with harvesting stem cells from human babies.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Guztavo on February 09, 2014, 02:27:38 PM
haha that's right. They just take some fat off your love handle and inject it back into your penis. Not sure what's wrong with that.

I didn't get any benefit so far though. Maybe others will.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on February 09, 2014, 04:04:29 PM
muffslayer, if this is your idea of trolling for laughs then we're not laughing. And you may be reported as a result.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on February 10, 2014, 10:01:23 AM
That was a VERY ignorant comment...Let's all just pretend that nothing was even said.

I'll keep you guys updated as things progress. They are doing a lot of work here and it's taking them 6 weeks to culture/grow/manipulate the cells, so I know they are putting effort into actually finding a cure for us and not just screwing around. Additionally, the procedure had to be performed in Mexico as this process is illegal in the U.S., mainly because the FDA deems this process to be effectively creating a drug, whereas in the U.S. it is basically injecting adipose tissue into the penis and hoping something sticks. If the FDA outlaws something, then that increases my faith in its healing power. There is an inverse correlation between actual cures and FDA approval in my opinion.

Also, both of the lead doctors have stated that they have seen some great results. One guy hadn't had morning erections in 3 years and now gets them every morning. If nothing else, that was enough for me to try this.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on February 10, 2014, 12:07:38 PM
rellisacct, perhaps I'm confused as to what this process is versus the stem cell treatment that is offered by a doctor in my area. Dr. Chen in Fairfield, CA does stem cell lab work and then one of the urologists he works with does the injections. This process is legal. What is it that you're having done that is different and makes it illegal according to the FDA?

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on February 10, 2014, 01:22:02 PM
The doctor from Wake Forest said that the procedures that are being conducted in the U.S. are just getting ADSC's from the fat tissue and then re-injecting without being differentiated into multiple lines and grown to get maximum number of cells.

The procedure in Mexico is culturing the cells and differentiating them into 3 different precursor lines (endothelial, smooth muscle, and nerve). They are able to get more accurate measurements on the number of each type of cell that they are injecting vs just taking adipose tissue stem cells and injecting. Additionally, they are growing the number of cells over 6 weeks so in theory they should get a large number of each type of cell for injection.

I'm not a scientist, but I do trust that the doctor I'm working with knows his stuff. Additionally, I'm not trying to knock the doctors doing work here, but to me it seems that this process is more specific and directed work towards regenerating penile tissue.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on February 10, 2014, 03:39:15 PM
Thank you for that info. It sounds like the process in Mexico is a great deal more specific and more effective. Once again the U.S. is lagging behind. I wish you great luck and success with it.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Guztavo on February 10, 2014, 07:36:38 PM
@rellisacct Do they have any tests or evidence in other patients that has fixed peyronies or curvature for them?

Would be nice if you could share.

Cheers and all the success with this!

BTW: when are you scheduled to have this treatment?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: muffslayer on February 11, 2014, 01:35:57 AM
Quote from: koolx on February 09, 2014, 04:04:29 PM
muffslayer, if this is your idea of trolling for laughs then we're not laughing. And you may be reported as a result.

Reported for what? I'm not trolling, just asserting my belief.

Albeit I was ignorant of the fact there are other types of stem cell research other than embryonic (until members of this forum pointed it out), and now I've done some research into it.

So let me clarify my belief. I'd rather have peyronie's for the rest of my life than support or use embryonic or fetal stem cell research. This is what I was originally trying to say.

If it's fat from your hip I have nothing against it. If it's from embryo's, then I'm fully against it.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MattFoley on February 11, 2014, 02:47:54 AM
I don't want to side-track this topic but I would have a serious moral dilemma if I was told that embryonic stem cells could cure my Peyronie's.

I don't know what I would do. I hope I'm never faced with that choice.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on February 11, 2014, 04:51:07 PM
@Guztavo  I'm not sure if they have any evidence of this correcting curvature in Peyronie's, however, curvature is not my main problem. Internal scarring, significant girth shrinkage, and impotence are my main problems and they have had some good success with this. I'm sure that this would have some impact on curvature as good cells would be taking over bad scarring cells in theory.

Thanks for the kind words...I hope this works for me which will then be able to benefit a lot of other guys on here. The actual injections will take place around March 15 time frame.

@Muffslayer/Mattfoley It would be a difficult dilemma for me as well knowing that only embryonic stem cells could cure my condition. I'm so far gone and have had so much of my youth destroyed by this disease that, with an element of shame, I can't say that I wouldn't go through with it. Luckily this is not a decision that we will have to make.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: emasculated on February 12, 2014, 04:27:58 AM
They are just cells in a petri dish. You have your priorities seriously screwed up in my opinion if you worry about a non-issue like that.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rd on February 12, 2014, 01:29:12 PM
I agree with emasculated. It would be hard for me at all to decide. If they told me embryonic stems cells would cure me my answer would be and easy YES! I wouldn't even give it a second thought. But to each there own.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: restore on February 12, 2014, 02:38:21 PM
Quote from: MattFoley on February 11, 2014, 02:47:54 AM
I don't want to side-track this topic but I would have a serious moral dilemma if I was told that embryonic stem cells could cure my Peyronie's.

I don't know what I would do. I hope I'm never faced with that choice.

The CNN report is exciting news since it says stem cells can be made quickly and cheaply WITHOUT use of embryos. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on February 12, 2014, 06:52:38 PM
Yes restore, you are right, but the new way to make stem cells quickly and cheaply is not yet implemented in any institution (as I know, maybe I am wrong)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: restore on February 13, 2014, 12:32:33 AM
Quote from: james1947 on February 12, 2014, 06:52:38 PM
Yes restore, you are right, but the new way to make stem cells quickly and cheaply is not yet implemented in any institution (as I know, maybe I am wrong)

James

Yes think you are correct, and this is just now breaking news.  But I believe the article did say that this new method will accelerate more research in that direction and probably bring the practical use of stem cell therapies sooner.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: jnbarizona on February 17, 2014, 02:04:09 PM
Hello again everybody. Sorry I haven't posted in a while. I wanted to update my experience so far with the stem cell treatment I underwent in December. I went to Dr. Lander in CA. I got an MRI before my procedure, which confirmed the location of the plaque. He did shock wave therapy before and after my injection of stem cells. I received 95 million stem cells, that were taken from my back. When he injected me, he noted that he could feel the plaque with the needle, and used the needle to break up the plaque. My plaque measures about 2 inches in length, but I can't always feel it, it just feels rigid(non-spongy) on that side of my penis. So far, there has been no improvement. In fact, it seems worse. I only had a slight bend before, now the bend is much more significant. I know I still have some time to wait to know for sure, but I have my doubts that this will do anything for me, other than empty my bank account. I will update again of any progress. I do have a couple questions for other members, so hopefully they are reading this...

@Rellisacct... it sounds like from your description of your symptoms, we have the same situation regarding our Peyronies Disease. I am very interested to hear about your results. Did you need a referral to see the doctor at Wake Forest? Was it necessary for him to go with you to Mexico to have this done?

@Guztavo... you said you don't have any plaque. I'm wondering, have you ever been diagnosed with Peyronies Disease? From my understanding, you actually have to have plaque to have peyronie's. So that also makes me wonder how you qualified as a candidate for the patient funded trial. I'm sorry it hasn't worked for you.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: e2219e on February 20, 2014, 12:34:26 AM
Stem cells are easily derived from marrow or fat.  It is totally unnecessary to use embryonic or fetal cells.  The idea is that, by delivering appropriate cells to the wound site, the body will remodel healthy, functioning tissue rather than scar (or plaque).  I am still learning about the disease state of peyronie's, but I would be skeptical of any cellular therapy that didn't first remove the plaque.  As I stated in a previous post, I am an independent rep for a company that sells a device that concentrates both PRP and bone marrow aspirate.  I have been involved with regenerative medicine for the past 7 years, and removing scars is typically critical when attempting to repair soft tissue.  I actually knew about peyronie's prior to suffering from it (onset in the last 12 months).  I haven't seen a single study which shows promise of a full, or near full, restoration, surgical or not.  The Nesbitt procedure seems barbaric to me.  I have a surgical idea which combines a biologic graft and PRP, and will be approaching a physician group about the idea.  If they are interested, I will approach them about posting before and after photos, along with technique.  If it works, and I believe it will, I will find a way to share the data with you all.  I'd prefer to avoid surgery, but none of the non-surgical approaches are working, and current surgical procedures often create a different problem. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: emasculated on February 20, 2014, 06:31:19 AM
@e2219e: Your thinking is absolutely right on this. I hope to read from you later what you found out. But how is the biologic graft placed? That would require excision of the plaque which is a quite invasive and risky procedure or did I not understand you correctly here?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on February 20, 2014, 09:40:13 AM
@jnbarizona   I did not need a referral and since this is a clinical trial that I'm participating in, the doctor did have to go to Mexico with me.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Knight on February 21, 2014, 01:11:44 AM
emasulated - e2219e clearly stated that he was skeptical of any cellular therapy that didn't involve removing the plaque first. I'm no doctor or anything close to an expert but based on my experience of what I am living with I completely agree. Unless the scar tissue/plaque is removed or somehow magically transformed into some softer form of tissue than it currently is I can't see anything making that much difference for any long term benefit or improvement. Invasive? Yes, they need to get in there and cut out the bad stuff and whatever is removed will have to replaced with new tissue, most likely a graft of some sort. It is what it is, isn't it?

I do question the whole degloving thing, but again who am I? It just seems in this day and age with all the technology and microscopic surgery techniques that some genius would recognize a market and develop a less invasive way of accomplishing the task than peeling all the skin off for access. Perhaps the combination of microscopic surgery, stem cell replacement and/or the P-shot might be a solution? Just typing thoughts here.....
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: mariobros on February 24, 2014, 07:52:21 AM
rellisacct, all the best of luck with your procedure it sounds very promising, much more advanced than the current methods available.

Am i to understand that this trial procedure was actually endorsed by a doctor at Wake Forrest?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on February 24, 2014, 09:53:06 AM
Thanks Mario, I'm not expecting a miracle but hopefully this will be a significant improvement from where I'm at.

Yes, I am flying down with the lead urological tissue engineering doctor from Wake Forest. He is actually co-head of planning for the AFIRM II grant from the US Government.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on February 24, 2014, 04:27:15 PM
One of the answers I got here where I am living while asking about Priapus shot is that they are doing Stem Cells injections for Peyronies.
What I should expect and after how long time from Stem Cells injections?

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on February 24, 2014, 05:48:40 PM
I wish I could tell you more, but I really have no idea James. I do know that much of what is going on right now in stem cells is a crapshoot.

It seems to me like most doctors are shooting a shotgun at a target and seeing how many pellets hit. 

I should be able to tell you more in a few weeks, but the primary answer that I've gotten is that stem cells along with growth factors will help to create new tissue and can break up some of the scarring. I'll give you more details as things progress.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on February 24, 2014, 06:49:26 PM
Thanks rellisacct

I will make appointment next month with two doctors in two different cliques. Both 1:30 hours flight from where I am living.
I have to be there in any case next month.
Before going forward with something, I will tell the forum what they say and ask for opinions.

James

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: jnbarizona on February 26, 2014, 10:59:29 AM
Dear Mr. Moderator(or whoever is running this thing),

I have been posting in this section recently, because I underwent stem cell therapy in December, and I wanted to contribute to the discussion. My most recent post was removed, why? I know that in that post I did mention the possibility of doing the Xiaflex treatment prior to injecting the stem cells, and I was curious to see what others thought. Maybe it's because I mentioned Xiaflex, or maybe it's because some idiot posted a negative reply in an attempt to start an argument. Either way you're wrong for removing my post. Hell, you have reps on here talking about PRP injectons, and also talk about surgery, but you have a problem with MY post? 

Look, if you don't want me here, and are not interested in my contributions, that's fine. If that's the case, I'll leave you all to your bickering. So you can just go ahead and delete this to, then I'll know to delete my account and move on.

Thanks.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on February 26, 2014, 01:07:46 PM
jnbarizona

I just checked your profile and find you have posted 7 posts.
I didn't see any links in your posts or profile so I don't understand how it happened.
It is very unusual that a moderator or administrator will remove a post. Even posts with commercial links we are just deleting the link.
I am checking now the subject to understand how it happened.
Please be kind and write down your post again.
Personally, I am very interested in your results as stem cells treatment for Peyronies is available here where I am living.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Norm on February 26, 2014, 02:18:25 PM
Jnb,
We don't normally remove posts unless they are spam. Looking at your posts, I do find one over under the Surgery board named "Re: Graft Surgery Procedure" where you talk about having Xiaflex prior to stem cell. Is that perhaps the post you think was deleted?
Norm
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: jnbarizona on February 26, 2014, 03:45:47 PM
@Norm... Yes, that was the post. However, I don't think it belongs in the Surgery section. I'm going to re-post it here again, per another members request. I guess if it's that much of a problem they can move it again. Thank you. I've decided to stick with the forum, I just got a little ticked off about it I guess. I'm trying hard to find a fix for this problem that's ruining my life.

@James... I had my stem cell injection 10 weeks ago, so far no improvement. The doctor said usually 3-6 months to see if it works, but he said no results are guaranteed. I didn't have a significant bend, but since the stem cell therapy my bend is worse now. The doctor did shock wave therapy on Monday... lipo from my back, shock wave again, and stem cell injection on Wednesday... and finished with shock wave again on Friday, so it was a week long thing. He noted when he was injecting that he was using the needle to break up the plaque. There was a lot of blood, and I was bruised for over a week, plus swollen for several weeks. It still feels sore all around the target area, and I have a small lump at the injection site not. I'll update of any changes. I wish you good luck if you decide to give it a try. I just wish I had better news to report about it so far.

My condensed previous post... What if I did the Xiaflex injections to break down the plaque(yes, I am aware of the risks of Xiaflex), then completed the treatment with my stem cells. Anyone have thoughts on that idea?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Norm on February 26, 2014, 04:35:32 PM
No one moved it in the first place. We cannot move posts no way, no how without a trail showing that it was moved and why. That is where you posted it. We can, however, move it if you would like for us to. That is easier than having you re type it. Just say the word.
Norm
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: anonpdacct on February 26, 2014, 05:40:51 PM
Hi everyone,

JNB asked below: 'what if I did Xiaflex injections to break down the plaque... then completed with stems cells...'

Here's a patent application that talks about exactly this.  The author was at AMS at the time.

TREATMENT OF PEYRONIES DISEASE - Patent application (http://www.faqs.org/patents/app/20120156178)

I would love to hear folks comment.

JNB - I'm sorry your treatment hasn't delivered the results we are all hoping for.

best,

Anon
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: emasculated on February 26, 2014, 06:04:58 PM
Ordinary Xiaflex alone carries the risk of rupture of corpus cavernosum. "A high pressure injection device" doesn't sound very safe.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: jnbarizona on February 26, 2014, 06:58:52 PM
@Norm... I swear I posted it here, then it moved, that's weird. Anyways, thank you and I apologize for the confusion.

@emasculated... I already mentioned in my post that I am aware of the risk involved. Thank you for your comment.

@anonpdacct... Thank you! I'm going to read through that tomorrow.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Knight on February 27, 2014, 06:20:33 PM
@anonpdacct - Thank you for posting that link! I CAN'T BELIEVE IT BUT I LIVE RIGHT DOWN THE ROAD FROM THIS NATELIE ANN BORGOS! You can bet your bottom dollar I'm looking her up!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on February 27, 2014, 06:28:15 PM
I try to read (and to understand) the patent but I don't understand to much.
Is this an available treatment?
Can contact Natalie Ann Borgos and get the treatment?

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Knight on February 27, 2014, 06:29:10 PM
Weird....after a few quick searches I'm not sure she even exists? You'd think this person would have a medical profession and would be easy to find with the internet but so far no luck. It looks like her and her husband have applied for several patents but haven't received any. I'll keep looking....
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: anonpdacct on February 27, 2014, 06:37:17 PM
I think if this treatment regimen were being practiced today by real doctors, we'd know about it.  The application merely presents theory and arguments for why this protocol could work.  I'm trying to find out whatever else I can, but not very optimistic about getting information more useful than what's there.

Anon
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: jnbarizona on February 27, 2014, 06:44:53 PM
@Knight... please let me know if you find her, I'd be interested to hear what she has to say. I'm going to speak with some other doctors in the near future about this method as well.

@James... it's unnecessary to read through the whole thing. The 'Abstract' paragraph at the beginning sums it up. I agree with Anon that it's mostly a proposal. I'd be mostly concerned with at what point the stem cells are being injected. I would think you'd do the X treatments first, then follow up with stem cells a short time after.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: e2219e on March 02, 2014, 10:54:39 PM
emasculated - Sorry it has taken me this long to respond.  I have yet to get in touch with the physicians.  I will keep you posted.  Graft placement and plaque removal would require surgery.  I need to sit down with a thoughtful surgeon and walk through the surgery with them.  I believe the invasiveness of the procedure will be dependent on the amount of plaque and the area it covers.  I have not been in the OR for a penile procedure, so I am not sure what the options for entering the site are.  De-gloving, while it sounds awful, may be the best option, as the scar can be hidden, and you are creating less trauma near the injury (plaque).  And, as the plaque often encircles the effected area, it gives the surgeon better access to the site.  If the plaque could be removed percutaneously while using a small camera or fluoroscopy, you'd still have to be able to place the graft securely. It could be possible to put the graft material in through a very small incision (say where the camera or debridement tool was inserted, and then unroll it and place it over the area where the plaque was.  This is where it would get even trickier.  You would need to secure it into place, which is easily accomplished in a de-gloved situation, but much more complicated percutaneously.  Fibrin glue works great with the graft material I'm thinking of in other areas of the body, but I don't know if the delicate tissues in the penis would react poorly to a material that can be rather hard, and even sharp, upon setting.  Sorry to ramble on.  It may be possible, but that doesn't mean better. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on March 16, 2014, 05:27:29 PM
Some news:
p.s. 75$mil was invested for tissues regeneration research including Genital area.

Genital Injuries - Wake Forest School of Medicine (http://www.wakehealth.edu/Research/WFIRM/Projects/Genital-Injuries.htm)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on March 25, 2014, 06:43:21 PM
An other interesting article regarding Stem Cells.
Not for Peyronies, but encouraging.
First stem cell study of bipolar disorder offers hope for better treatments | Fox News (http://www.foxnews.com/health/2014/03/25/first-stem-cell-study-bipolar-disorder-offers-hope-for-better-treatments/?intcmp=obnetwork)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on April 21, 2014, 08:18:41 PM
I dont know how relevant this may be, but I read this article on scarring. Its worth a reading:

Tissue scarring in scleroderma: New clues -- ScienceDaily (http://www.sciencedaily.com/releases/2014/04/140418141240.htm)

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on April 29, 2014, 05:52:43 AM

Regenerative researchers have grown vaginal organs - Winston-Salem Journal: Business (http://www.journalnow.com/business/regenerative-researchers-have-grown-vaginal-organs/article_31a91c78-c199-11e3-bebc-0017a43b2370.html)

Now we got not only Priapus Shots, but STIM™ shots as well.

S.T.I.M. Therapy for Penile Enhancement (STIM™ Therapy) | Artisan of Beauty | Beverly Hills (http://www.artisanofbeauty.com/blog/s-t-m-therapy-penile-enhancement-stim-therapy/)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on April 29, 2014, 07:50:57 AM
The subject was discussed here:
https://www.peyroniesforum.net/index.php/topic,4876.0.html
Priapus, PRP, STIM all all the same

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on May 01, 2014, 08:44:32 PM
I have said the same thing ages ago when priapus first came up in discussion in the forum.. for the last time, PRP = Pirapus

Priapus is just a cosmetic marketing name for PRP, nothing more.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on May 01, 2014, 09:00:45 PM
Yes Koolx, you have said it, just not ages ago, incautious opened the Priapus topic at February 13, 2014. :)
Let's continue on this topic with stem cells, not with PRP.
We have other topic on PRP

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on May 05, 2014, 02:33:47 PM
Hey guys,

So it has been over a month and a half since my stem cell procedure (March 15) at Wake Forest and I have mixed emotions. If anybody has been following my saga of PRP/Stem Cell trials, then you will know that it has been a rollercoaster with more downs than ups, however, I will try to give you the positive and negative results of the procedure.

Background Basics: I had a mix of PRP & ADSC's (Adipose Derived Stem Cells) injected into the penis along with a special gel of growth factors. The full process took about a month and a half to perform. On the first trip I flew down to Mexico with the lead urological tissue engineer from Wake Forest University. I went under general anesthesia and had liposuction performed on my abdomen in order to harvest the stem cells. Over the course of about a month, they differentiated and expanded the cells into three different lines...Epithelial, Smooth Muscle, and Nerve Cells.
On the second trip, I was again put under general anesthesia and the ADSC's, PRP, and gel were injected all over the penis and that was basically it.

Positives: I went from having zero ability to get a meaningful erection (we're talking a hanging piece of scar tissue) to being able to get an erection while on Cialis (only 5mg daily). This in and of itself is remarkable. The firmness is decent and is hard enough for sex, although I'm nowhere near my pre-injury days. Additionally, I have met a girl and we've hit it off over the past month. We've had sex a few times and she had no clue that I ever had any problems until I told her a little about my history. For the first time in about 2 years I really feel alive again!

Negatives: The size is no where near where I used to be. I've lost about an inch in length and probably about 1.5 inches in girth. The ADSC's did not fill out the penis quite as much as I was hoping they would, but going from the dark depressive hell that I was in to where I'm at now...it's night and day. I believe that for people who have less scarring and shrinkage than I had and have a more localized plaque or indention, this procedure could be a near cure. Also, people who just have old penile tissue that needs a little rejuvenating, this could work miracles. Please don't misunderstand...I'm not calling this a cure, but I do believe that this has the possibility to improve people's condition significantly. Last negative: It's freaking expensive. We are talking down payment on a house expensive. 

Overall, I still will be looking forward to the day when they can do complete replacements of the tissue, however, I'm hoping/praying that this will hold me over until that day comes. If you have any questions about anything, please let me know.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on May 05, 2014, 04:56:37 PM
rellisacct

First congratulations for the positive outcome:
Quote...For the first time in about 2 years I really feel alive again!
Two things are bothering me:
The very high price. Maybe you posted how much is costing you, please let us know again.
Two general anesthesia. I am scarred of it.
As I understand things will improve as you are just 7 weeks after the treatment. :)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on May 05, 2014, 05:18:28 PM
Thanks James...

The very high price is around $15,000 including flying the doctor and myself down to Mexico and back twice. This has literally taken the downpayment on the house that I was going to buy. It's more than worth it to me to be able to have sex again, so the house can wait a year or two.  ;)

The general anesthesia was very light, so no problems at all with that.

Just as with any new technology, the price of the procedure will come down in time. I'm hoping that this will be available to more people in the near future, but there's no way of knowing. I wanted to write this primarily to keep people's hopes up.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on May 05, 2014, 05:22:41 PM
QuoteI wanted to write this primarily to keep people's hopes up.
Thanks for that rellisacct and continue to update us in the future

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on May 05, 2014, 11:28:42 PM
james1947, first off, you dont need to remind us when Incautious first mentioned this PRP topic. Second, it was ages ago since he brought up this topic while we're in May and the topic keeps coming up for the past 3 months. Its best that you advise the original poster of this topic to end its recurrence, not the ones complaining about it. 

rellisacct, very happy about your progress. My prayers are with you, brother.


Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on May 06, 2014, 03:48:32 AM
koolx

I don't understand your post, maybe I should clarify mine:
* This topic is about stem cells, not about PRP/Priapus/... We have an other topic regarding PRP to discuss the subject and not here.
   Discussing here PRP is hijacking the topic.
* 3 months are not ages for me.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on May 06, 2014, 08:31:46 PM
James,

Exactly, the thread is about stem cells not PRP. You just made my point.

Youre strange to think that talking about the same topic for 3 months isnt a long time... yeah ok.

Your post makes no sense. Oh well, on to more important things....
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on May 07, 2014, 06:18:31 AM
Let it be koolx, appreciate your attention :) :) :)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: koolx on May 08, 2014, 07:22:41 PM
Thank you, James. I appreciate all your input and contribution to the forum.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Chef Chris on May 10, 2014, 03:15:31 PM
Any body tried this treatment?
Peyronies Disease (http://www.stemcellrevolution.com/currently-studying/urology/peyronies-disease/)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on May 10, 2014, 06:48:27 PM
Some remarks regarding the link:
QuoteThere is an ongoing FDA study of a drug (phase 3) called Xiaflex
Not updated, the trials ended, FDA approved already.
QuoteNon-surgical therapies include: Vitamin E, Potaba, colchicine, tamoxifen, carnitine, and Omega-3 fatty acids.
No mention of Pentox and Cialis that leading urologists are using as oral treatment.
QuoteStromal Vascular Fraction (SVF)
Is a name he is using for stem cell therapy. On this topic itself we have the testimonies of forum members that had made this therapy.
Interesting to know how much they are charging.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Chef Chris on May 10, 2014, 06:58:55 PM
Yes i was thinking about the Adipose-derived Stem Cells treatment he is providing
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on May 10, 2014, 07:01:27 PM
I am also sure they are making good money from desperate people like us :(

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: op on May 12, 2014, 05:36:50 PM
rellisacct, thank You for such fresh & information based posts! Also, as i remember no one have posted(sorry if I've missed) about stem cells being filtered & etc... to: Epithelial, Smooth Muscle, and Nerve Cells. That's something new...


Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on May 12, 2014, 05:53:04 PM
No problem Op, I'm thankful that I'm able to share such information.

Wake Forest is the only place that I know of right now that is differentiating and expanding the cells before injecting. I believe that this is a major reason that the procedure worked as well as it did.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on May 15, 2014, 08:41:10 PM
It seems we are on good track for Peyronies also in the future:
Stem cell therapy shows promise for multiple sclerosis | Fox News (http://www.foxnews.com/health/2014/05/15/stem-cell-therapy-shows-promise-for-multiple-sclerosis/)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: stopthismadness on May 16, 2014, 01:57:38 AM
Thank you for the post James, that is indeed very encouraging. Now i just hope that it happens quickly for us humans.  8)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Crankitup on May 26, 2014, 01:11:35 PM
Are we averse to sharing pictures on this forum? Because I've never seen any even though our disease sort of naturally takes to description through pics more than the word trains always found here.

Rellisacct, really happy for you, man. And very good to know that "they're doing a lot of work" down there in WF. I don't put a price on ridding this problem but I do hope they improve on the size loss front a bit more.

So I understand nobody around here benefited much from injection of undifferentiated cells?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on May 26, 2014, 05:34:41 PM
Crankitup

You can post pictures on:
https://www.peyroniesforum.net/index.php/board,47.0.html
The board above can't be seen by search engines and guests.
We made it this way not to attract people that have other interests than find solution for they Peyronies.

james
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: jmsurfer on June 01, 2014, 09:57:56 PM
Does anyone know if the treatment relissact got at Wake Forest ( stem cell treatment in Mexico) is still available or is it not because it was done in the setting of a clinical trial? Do you guys think there are any risks of worsening ED from this?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on June 01, 2014, 11:09:14 PM
jmsurfer

Hope rellisacct will answer you, can also send him a PM

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on June 02, 2014, 09:37:22 AM
Sent you a PM Surfer
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: MACCC on July 01, 2014, 09:01:51 AM
i am very much interested also to know if the treatment relissact got at Wake Forest ( stem cell treatment in Mexico) is still available or it is something quite far from available generally to all peoole? I got a very localised plaque and ED and really wish it could be a cure.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on July 01, 2014, 09:28:15 AM
Hey Maccc,

It was a very long process for me to be able to get into the clinical trial. I had to literally exhaust every other option before they would allow me to go that route. I would strongly suggest going with PRP first and seeing how things go with that, especially if the plaque is localized. The stem cells were more for rebuilding the corpus cavernosum, which it appears that this may not be an issue for you?

I believe that they will be expanding the trial fairly soon since they have had some really good results. Where are you located? It helps that I'm literally an hour down the road from their urology office.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Crankitup on September 03, 2014, 01:12:50 PM
Hey all :) It's been 2 months since the last post. Any interesting updates?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on September 11, 2014, 05:08:18 PM
Nope...been scouting out the depression and suicide boards lately. Unfortunately nothing further to add here.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on October 22, 2014, 03:07:36 PM
Guys...News???
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Fubar Penis on November 29, 2014, 10:06:12 PM
From what Stan with APDA, who sat down with the leading researcher spear heading the stem cell research for body parts and penises, he said we are at least a decade or two from fully testing it out on humans for full treatment of penis issues. By the way, it is mainly being researched to replace missing penises for like veterans who lose theirs during war, for transplants of cadaver penises using stem cells as the bonding agent or to assist in making the penis a part of the tranplantee's own body. How it will be used for peyronie's or if real research money is going into it for that purpose is still up for debate. From what I heard, the other issue is we would probably still have to have some form of surgery to remove the scar tissue and then implant the stem cell graft to grow new cells. I don't believe you can inject the stem cells and have them replace or dissolve the plaque causing our problem to start with, if I understood what was told to me correctly and what I read. Once again, nothing is clear cut and dry with this nasty condition. I just keep hoping that in a year or two or tomorrow, they find a way to safely remove our unhealthy penises and replace them with John Holmes penises. Lol! Then also keep in mind, like our current surgery options, insurance is probably not going to want to cover most of it; and I would imagine it would be hella expensive. You know if they could replace safely our penis with a John Holmes penis, they would be charging a million dollars for the surgery, since every man with money would be in line to to get one. Maybe with these 3D bio printers being developed, we can eventually all have new penises after we rob 5 big banks to pay for it. Lol!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Crankitup on December 02, 2014, 03:21:14 PM
@Fubar. Wow that is really depressing news, tbh. I was hoping in 5 years there'd be a change in landscape, if not much else. Who did Stan sit down with exactly?

Btw, I just saw that futurologists are predicting complete organ replacements by 2020.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on December 04, 2014, 05:38:15 AM
Guys.. I don't think so... The studies of Dr.Atala are very positive...I think (and hope) that the defenitive care it will in five-seven years..
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Fubar Penis on December 04, 2014, 01:20:51 PM
Crankitup,

He had a conversation with Atala directly I thought. He didn't sound real hopeful for a cure for our peyronie's in the next decade or so, but I hope Lollaro is right. I hope and pray Lollaro, you are right. I thought he said Atala said the primary focus will be on replacing missing body parts, not in curing peyronie's. You know the FDA is too. If the cure is found in 7 years, it will take another 7 years to get approval. Europe will probably be curing peyronie's 5 years before we get approval approval to do so. I guess then it would be time to sell the house and maybe sell some crack (just joking of course-but you know the surgery will cost a fortune) and move to Europe for me.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on December 05, 2014, 03:45:34 AM
https://www.google.it/url?sa=t&rct=j&q=&esrc=s&source=web&cd=4&cad=rja&uact=8&ved=0CD8QFjAD&url=http%3A%2F%2Fwww.huffingtonpost.com%2F2014%2F10%2F09%2Flab-grown-penis-human-testing_n_5953806.html&ei=fnCBVOfDD4i7PZ2mgLAF&usg=AFQjCNEh65gbt5GBoWOoqJKQbaNN1mRIeQ&sig2=KjbpYbv5KRK_K_BnqSvMSA&bvm=bv.80642063,d.ZWU This is the link of the interview
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on December 05, 2014, 04:07:37 AM
Thanks for the link Lollaro.
5 years is not a long time, especially for the younger between us.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on December 05, 2014, 05:30:23 AM
Yes... i have 18 years ...

How much u think the costs of the surgery?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on December 12, 2014, 12:19:36 PM
Penis replacement trials are going to begin much sooner than that, but not in America. The good and moral folks over at the FDA are, as usual, slowing the clinical trial process to a snail's pace. In order to get things moving, the clinical trials will begin in Mexico by Spring 2016 at the latest. The only holdup is that Wake Forest is currently waiting on the the AFIRM II funds from the military to come through before proceeding to plan the procedures and clinical trial protocols.

Additionally, the research beneficiaries definitely include individuals who have severe peyronie's disease as well as congenital abnormalities, injuries, etc.

This is straight from the doctor that actually heads up the research and will be administering the trials. The only thing keeping this from being in clinics and widely available in 3-5 years will be our own government.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on December 13, 2014, 05:39:46 AM
it's good news
Rellisact .. but it would be better to wait for the Wake Forest is
move in this direction ?? Would not it be a better certification?
Who guarantees that in Mexico they can actually do a good job?

Edit : Will be able to regain the structure exactly as it was before the injury?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rellisacct on December 18, 2014, 02:48:34 PM
Lollaro,

The clinical trials in Mexico would be administered by Wake Forest, with Wake Forest doctors. Additionally, some of the primary researchers are Mexican and thus have the expertise needed to perform the procedure. So actually it will be U.S. doctors in charge of the procedure with help of the Mexican researchers.

I have been down to the hospital where they will do the procedure and it is a world class research lab/operating room. They had a large financial gift from a private individual with our condition which went into upgrading their equipment and lab to the point that it needed to be to proceed with clinical trials.

There is absolutely no promise that the structure will be like it was before and there is no guarantee that the procedure will even work. They have 20 years of great research history behind them which hopefully will translate into a human cure. In theory, there shouldn't be much of a difference in how the penis used to be and how it will be post-op. There is no guarantee in any surgery, especially one that hasn't been performed before.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on December 19, 2014, 07:06:52 PM
Rellisact .. I meant the expectations of care ..
It should be a permanent cure? That hypothetically could bring the penis before? Can you tell us more about how?
O the methods?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on January 18, 2015, 08:46:45 AM
news??
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: diamondback55 on January 18, 2015, 09:10:45 AM
Rellisacct, Can you please give me the contact information for the doctor you were working with at WF?  I suffer for straight ED and would like to discuss treatment options.  My email address is stcampbell01@gmail.com .  Thank you.


[Full quote removed by Admin]
Please read the forum rules regarding quoting. To optimize the forum we ask the you hit the 'Reply' instead of 'Quote' feature on the forum. If you choose to quote someone then edit out the non-relevant parts of the quote.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: RodFUBAR on February 25, 2015, 01:09:41 PM
Hello comrades, I'm new here and this is my first post. I recall reading on here somewhere, some time ago, that there was some clinical trials taking place for stem cells and there was this doctor in San Francisco or San Diego who's looking for guinea pigs. I'm sure I'm too late but wanted to know whats it all about and am I on the right thread? I recall something like growing new corpus cavernosum, and rabbits, and what not lol... I'm down to experiment with growing me a new corpus. Now does this experiement require injecting stem cells into our existing one or grow us a new one and swapping them?
Don't see why we cant grow ourselves a new penis (overdosed on hgh & testosterone of course) in a lab, or be on a waiting list from organ donors? Anyone think organ donations will ever include penises? Thanks folks, I welcome all information and help on the subject.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on March 04, 2015, 05:54:16 AM
Penis transplant was performed in 2006. Surgery went good but the patient then asked for being removed it because of psychological problems. Anyway, penis lab grown is the way Dr Atala is reaching. He has already created and implanted parts of penis and entire vaginas. He is about to start human trials for entire penises. The obstacle to overcome, from what I heard, is the fact the penises implanted show a weak erectile power..not absent, but as a 60 years man. In any case, it's not the worst problem they could come across.
I also think that the psychological wall of seeing a different penis will be climbed up by using 3d printers. 3d printers can recreate your penis shape exactly.
Last year in Holland it was performed the first skull 3d Printer created in a woman suffer from a rare disease that prevented her from having a normal life. They recreate it perfectly, and not because of psychological issues, but because it needed to fit to the head and the brain.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on March 04, 2015, 06:07:50 AM
Quote from Jack1909
Quote3d printers can recreate your penis shape exactly.
Unfortunately I don't have pictures of my original strait, pink penis and I don't want they will make me a penis based on what I have now. :(

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on March 04, 2015, 06:32:06 AM
James your penis is bad even when it's down?

James, I read about your link about stem cells sued for treating Sclerosis multiple..right yesterday I came across an article where it was explained that in GB they are already (!) using a cure defined as a miracle. Practically your immunological system is swept away (you need to stay isolated for a while) and reprogrammed by using stem cells. People gained back sight and legs and so on. It's a real extreme way to approach..but I wondered if could be a way to approach even for your problem.
In general, we should be more optimistic about stem cells. I know, we have been hearing about them for years..but someone knew that it has been approved the first stem cells drug last month? The first one in the world (and it is italian..don't know how it's possible :D) and is very working. It let you gain back your sight by regenerating part of the eye. So, this is the proof we are on the way to fix things..


I've read some posts below..it's clear that Atala's way is not the Peyronies Disease's cure, it's the way to have a new healthy penis. But I think that all of you will accept to remove their penis for a new one sane.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on March 04, 2015, 02:02:58 PM
My post was more to put some humor in the very serious topic Jack.
I am active sexually, but I miss my lost 2", lost girth and capability to maintain an erection as long as I wish. ;D

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on March 04, 2015, 03:11:32 PM
Hey Guys ... News about Atala's studies?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: chefcasey on March 04, 2015, 04:17:52 PM
I like the prospect of growing a new penis, but most guys here wouldn't even need that.  I think just growing parts of the penis we with Peyronies Disease actually need, like the tunica or corpora would be in the pretty near future.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on March 05, 2015, 06:38:53 AM
Totally agree
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Amitr on March 05, 2015, 08:57:58 AM
Guys, I just happened to read about Atala's work and came here to post if anyone had read about it.
As it turns out you guys have already.

I've always felt that stem cell research is probably the most promising hope for us and many people across the world would be benefited from developments in the field.

So if there's any way we can contribute to studies, many would be interested. It'd be great if we could have a clearer channel for communication between us and researchers like Atala, over here or on another popular forum like reddit, so people interested to contribute monetarily or as subjects would have an easier time doing so.

Secondly it'll help us have greater visibility on what we can expect in the near and distant future and plan accordingly.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: trevordd on March 06, 2015, 04:50:44 AM
Stem therapy is a really great ways to treat a huge number of diseases. From liver cirrhosis to Myelodysplasia... There are already some clinics like UCTC which have successfully implemented such a treatment method. It works really great.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on March 06, 2015, 06:26:20 AM
trevordd

Can you give us some details regarding your connection to Peyronies?

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on March 10, 2015, 04:09:03 AM
Guys news from Atala studies or Mexico?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: drew67 on June 13, 2015, 09:34:32 PM
Perhaps this could be applied to peyronies: Gallagher: UBC achilles research could be key to revolutionary treatment (http://www.theprovince.com/health/Gallagher+achilles+research+could+revolutionary+treatment/11044231/story.html)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on June 13, 2015, 10:21:28 PM
Thanks for the link Drew.
It seems that it will be good for Peyronies also
I just hope they will go fast forward with the research and not slow as everything with Dr. Atala.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itachi on July 01, 2015, 08:56:05 PM
Hi guys i think i found a stem cell treatment in HUMANS. Here is the link of the article.

http://www.cellztherapy.com/wp-content/uploads/2015/04/URO-stem-abstracts-PDF.pdf (http://www.cellztherapy.com/wp-content/uploads/2015/04/URO-stem-abstracts-PDF.pdf)

"DETERMING THE EFFECTS OF STEM CELL TREATMENT ON PEYRONIE'S DISEASE IN HUMANS"
by Dr Michael Zahalsky and al.

There are 5 patients enrolled in the study.
But you all need to consider that Dr Zahalsky injected the Stem Cell IN AND AROUND the plaque and not only around the plaque as it was the case for some guys in this forum. For those who had stem cell injected around the plaque but not in the plaque in this forum, it could be the reason for the poor results of your treatments. Stem Cell injection works as other intralesional injection for peyronie (verapamil, interferon, collagenase, etc.) it must be done IN the plaque. The other treatments are all done IN the plaque that's why we call that INTRAlesional injection. Dr Zahalsky did the injection In, Around and "evenly" in each corpora at he base of the penis.
-> As he wrotes :  "Up to 2.0 cc of our diluted PM−MSCs was then injected in and around the Peyronie's plaques. The remainder of the PM−MSCs was then injected evenly into each corpora at the base of the penis. "

I also want to tell you something else about Dr Atala's work. Tissue engineering aim to replace damaged tissue by new healthy tissues. I read ALL Dr. Atala's articles and what Atala tries to do is NOT developing a intralesional stem cell treatment for the acute phase of peyronie's disease but he tries to create NEW tunica albuginea that could be use for grafting surgery. Because currently all the grafting surgical treatments use grafts materials (autologous grafts, dermal grafts, synthetic grafts, etc.) that or not absolutely similar to tunica albuginea features. As Dr Carson and Dr Chun said in this article (http://www.nature.com/ijir/journal/v14/n5/full/3900864a.html (http://www.nature.com/ijir/journal/v14/n5/full/3900864a.html)) ideal grafts for penile reconstruction should have the following features : Pliable and compliant, Low antigenicity risk, Low infection transmission risk, Minimal inflammation, High tensile strength, Packaged, Multiple size available, Reasonable cost. But currently there is NO grafts materials that have all these features together. So that's the reason for the need of creating New Tunica Albuginea with stem cell. People prefers grafting surgery because plication reduce penis size. Patients are less likely to lose length with the grafting surgery but one of side effect can be erectile dysfunction and patient who suffered of erectile dysfunction before the surgery are more likely to suffer after the surgery. There is a few reasons of postoperative erectile dysfunction (ex. preoperative dysfunction, age > 60 years old, ventral curvature, etc. (sorry i forgot the link for the article, i will send it to you if i find it again)) and one of these reason is also the Graft Materials that currently exist, because as i said before, the graft materials we currently use to replace the damage tunica albuginea aim to have the same features as tunica albuginea BUT THEY ARE NOT TUNICA ALBUGINEA. In an article, Dr Atala said that if we can create new tunica albuginea it could avoid the side effect of the currently grafting materials. As he wrotes : " Currently, diseases such as Peyronie's are treated with plaque excision or incision and grafting of the tunica albuginea with materials such as small intestinal submucosa, fascia, and pericardium. All of these materials have drawbacks, including limited availability, donor site morbidity, and limited effectiveness. The use of a bioengineered tissue would be able to overcome most of the limitations of current techniques while allowing for lasting results". Dr Atala. Here is the article link http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253692/ (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253692/)

I really want to tell you an other IMPORTANT things.
Currently there is a grafting surgical treatment that can restore your (maximum) penile length and girth that you lost because of peyronie's disease. It's a grafting surgery based on Geometrical Principles. And this lengthening surgery can also be done on patients who suffer of preoperative erectile dysfunction with a simultaneous penile prosthetic implantation. But only if it's done on Geometrical Principles as it had be done by Dr Egydio, Dr Perovic, Dr Sansalone, Dr Djinovic, Dr Garaffa, etc.
Here are some articles.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593786/ (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593786/)
http://www.ncbi.nlm.nih.gov/pubmed/21098900 (http://www.ncbi.nlm.nih.gov/pubmed/21098900)
http://www.jurology.com/article/S0022-5347(10)02554-1/abstract (http://www.jurology.com/article/S0022-5347(10)02554-1/abstract)
http://onlinelibrary.wiley.com/store/10.1111/j.1464-410X.2012.11590.x/asset/bju11590.pdf?v=1&t=iblesdwf&s=199c91d6e16e2964a352fa2edecc15387fc526ab (http://onlinelibrary.wiley.com/store/10.1111/j.1464-410X.2012.11590.x/asset/bju11590.pdf?v=1&t=iblesdwf&s=199c91d6e16e2964a352fa2edecc15387fc526ab)
http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2012.11582.x/abstract (http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2012.11582.x/abstract)
http://www.iclinics.org/video/Real-penile-lengthening-using-geometrical-complete-circular-incision-with-grafting-and-penile-prosthesis-in-Peyronie%2526%2523039%253Bs-disease/67c3cc740193634654a8c74082d19b05 (http://www.iclinics.org/video/Real-penile-lengthening-using-geometrical-complete-circular-incision-with-grafting-and-penile-prosthesis-in-Peyronie%2526%2523039%253Bs-disease/67c3cc740193634654a8c74082d19b05)

So if we can do New Tunica Albuginea (created with stem cell) grafting surgery based on Geometrical Principles it's gonna be the most effective procedure to treat peyronie's disease, to straighten and restore the initial penile size (length and girth) and erectile function that people lost because of peyronie's disease.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on July 01, 2015, 10:40:30 PM
itachi

Thanks for the information.
From the list:
Quote...it had be done by Dr Egydio, Dr Perovic, Dr Sansalone, Dr Djinovic, Dr Garaffa, etc.
* Unfortunately impossible to do it with Dr. Sava Perovic as he passed away in 2010.
* Dr Kuehass name should be directly after Dr. Egydio as he is using his technique very successfully according to our forum records.
By the way, what is your connection to Peyronies?  Are you a doctor? Or Peyronies sufferer?

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on July 15, 2015, 03:48:50 AM
If I had a plaque I would get in touch with the doctor of the study posted  below since is very impressive.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: kuaka on July 15, 2015, 09:40:03 AM
stem cells have much promise.  My daughter is having them used for liver work.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: diamondback55 on July 15, 2015, 12:55:03 PM


Background Basics: I had a mix of PRP & ADSC's (Adipose Derived Stem Cells) injected into the penis along with a special gel of growth factors. The full process took about a month and a half to perform. On the first trip I flew down to Mexico with the lead urological tissue engineer from Wake Forest University. I went under general anesthesia and had liposuction performed on my abdomen in order to harvest the stem cells. Over the course of about a month, they differentiated and expanded the cells into three different lines...Epithelial, Smooth Muscle, and Nerve Cells.
On the second trip, I was again put under general anesthesia and the ADSC's, PRP, and gel were injected all over the penis and that was basically it.

Positives: I went from having zero ability to get a meaningful erection (we're talking a hanging piece of scar tissue) to being able to get an erection while on Cialis (only 5mg daily). This in and of itself is remarkable. The firmness is decent and is hard enough for sex, although I'm nowhere near my pre-injury days. Additionally, I have met a girl and we've hit it off over the past month. We've had sex a few times and she had no clue that I ever had any problems until I told her a little about my history. For the first time in about 2 years I really feel alive again!

Negatives: The size is no where near where I used to be. I've lost about an inch in length and probably about 1.5 inches in girth. The ADSC's did not fill out the penis quite as much as I was hoping they would, but going from the dark depressive hell that I was in to where I'm at now...it's night and day. I believe that for people who have less scarring and shrinkage than I had and have a more localized plaque or indention, this procedure could be a near cure. Also, people who just have old penile tissue that needs a little rejuvenating, this could work miracles. Please don't misunderstand...I'm not calling this a cure, but I do believe that this has the possibility to improve people's condition significantly. Last negative: It's freaking expensive. We are talking down payment on a house expensive. 

Overall, I still will be looking forward to the day when they can do complete replacements of the tissue, however, I'm hoping/praying that this will hold me over until that day comes. If you have any questions about anything, please let me know.
[/quote]

I am participating in the Mexico trial myself this fall.  I make my first trip in Oct. 2015 for liposuction and my follow-on trip in Nov. 2015 for stem cell deployment.  Fortunately I am going with another patient so we are able to split some of the costs to save money.  I will keep everyone posted on the results.  If there is any advice you can provide on lessons you learned please let me know. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lucketts on July 15, 2015, 01:25:33 PM


Thanks Diamondback555.  I know that Wake Forest is on the leading edge of stem cell work.  Any idea why they couldn't/wouldn't  do the stem cell work right there at Wake?  I think that even though there is no FDA approval, that some urologists in this country are able/allowed to inject stem cells for peyronies.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on July 16, 2015, 12:21:17 PM
I wonder if it's possible to get in touch with dr. Atala since my case is unique and it needs a special and very individual evaluation.
Diamond..How did you schedule your appointment at Wake Forest? Following the instructions provided on the website?
I would need some specific information since I would come from Italy..I would not take a plain and the find out that the treatment is not feasible to me.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: mike jones on July 25, 2015, 04:32:45 PM
According to this email replacement Erectile Tissue will begin being test by 2016
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: drew67 on July 25, 2015, 06:27:14 PM
I wonder if tissue replacement could also fix venous leak.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: mike jones on July 26, 2015, 02:07:13 AM
It should because the scar tissue is what causes the venouse leakage. Because the scar tissue can't expand enough to close off the veins to hold the blood in
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on July 27, 2015, 07:27:14 AM
Great news!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on August 26, 2015, 10:46:49 AM
Jack1909 - please use the Reply button at the top of the thread instead of the post Quote button. You have posted full quotes several times that we don't allow without editing. PM me if you don't understand.


I sent you a private message more than once..can you respond please?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lollaro on August 28, 2015, 06:39:22 PM
It's a series of great news. Also i , i'm interesting to Dr.Atala studies . Also i come from Italy
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itachi on September 02, 2015, 03:47:23 PM
hi guys,
i think we should clear things. Or we talking about stem cell injectiont herapy or tissue engineering using stem cells? Or both of them? Because one is more for the acute phase, the other more for chronic fibrotic phase and will be use as an surgery procedure (replace damage tissue by new healthy tissue). Dr Atala's work are the second one (tissue engineering). there is other urologist trying to develop the first one (stem cell therapy injection). So i think it's important to mention what we are talking about when we post something.

About tissue engineering, Atala and his team seem to be the only one to experience tissue engineering for the penis in the medical world (may i am wrong?)
I have to be septic about Atala's work. Someone on the forum got an e-mail response from Wake Forest in which it said that they will first treat soldiers (don't forget that their main budget comes from the army, about 200 millions $, that's why they'll begin with soldiers). Unfortunately for civilians it won't be available anytime soon ! So we'll have to wait for this ...
And about Atala's work, he said that to build an entire penis is that much complicated that it's not gonna be available in a near future. But they will begin with partial surgery, mostly smooth muscles and endothelial cells. BUT Atala never said that he and his team are engineering tunica albuginea, neither that they will for the moment. I read an article where he talked about an experience (tunica albuginea engineering) done by other urologists (not of his team) but on pigs (not on humans) (Tissue Engineering of the Penis (http://www.hindawi.com/journals/tswj/2011/323989/)).
What peyronie's sufferer need his a new tunica albuginea .... not an entire new penis. It's the tunica albuginea that is damaged in peyronie's disease. Ok if you have peyronie and corporal fibrosis (or other tissue damaged) yes ... you also probably gonna need other tissues replacement. But even in the case that we'll be still alive when this procedure gonna be available for us (LOL) they won't transplant us an entire penis if you it's only our albuginea that is damaged.

You know ... tunica albuginea seems to be (for me) a more simple tissue to engineered than the corpus cavernous which it's way more complicated as it includes the most part of the erectile tissues and erectile mechanism, which is complicated. We already have tissue materials (small intestinal submucosa, fascia, and pericardium) to replace damaged albuginea in a graft surgery but we don't have tissue materials to replace the corpus cavernous ... So yes i think tunica albuginea engineering seems more simple than corpus cavernosum enginneering. But At Wake Forest they are working on smooth muscles and endothelial cells for the moment (i am not telling that it's not important ... don't misunderstand)
Atala said that they need a donor's penis, it's the only way to have a scaffold to build an entire penis (because they won't use a 3d print for the moment). But if we or talking about tunica albunigea, the scaffold needed is way more simple to get.



Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: stopthismadness on October 12, 2015, 09:44:43 PM
Found this yesterday, I don't know if there is any merit to it at all but it says amniotic stem cells were used.

First Stem Cell Study for Peyronie's in Humans Shows Promise
Dr. Zahalsky Speaking at IV World Congress of Medical Sexology October 10th

CORAL SPRINGS, Fla., Oct. 8, 2015 /PRNewswire/ -- Unless you were living with it, it's likely you were unaware of male sexual dysfunction until the late 90's when pharmaceutical companies started huge campaigns for treatment of Erectile Dysfunction (ED).

Erectile Dysfunction isn't the only form of male sexual dysfunction. A condition called Peyronie's Disease has gone largely overlooked, and existing treatments haven't met with much success. Dr. Michael Zahalsky, a Florida urologist fellowship trained in male sexual dysfunction and pioneer in the use of biologics in Urology, is on a mission to help men affected by all male sexual dysfunction. As a result of his work, patients are experiencing groundbreaking success, thanks to the help of a trial using amniotic stem cells and growth factors.

Peyronie's Disease (Peyronies Disease) is characterized by the presence of fibrous plaque that causes an abnormal curvature of the penis during an erection. Often, this can make it difficult and painful to obtain or maintain an erection. It's been estimated that up to 7% of the male population is affected by Peyronies Disease. This week in The Journal of the American Osteopathic Association, Dr. Zahalsky published his groundbreaking results using amniotic stem cells and growth factors for Peyronie's Disease. He says his research on ED has already been accepted for publication in the same Journal.

"Patients who suffer from male sexual dysfunction suffer from so much more than the inability to perform," says Dr. Zahalsky. "They're generally unhappier, and can suffer from lack of confidence, depression, anxiety, sleeplessness and more. Because Peyronie's can affect young men, it can have a damaging effect on their overall happiness. We had to find a better way to treat this."

The most promising results of the study included the effect of the treatment on fibrous plaque material found in the penis: 7 of 10 fibrous plaques disappeared completely, all patients had an improvement in blood flow, and curvature of the penis dramatically improved.

"We believe this was the first ever study on the use of injectable stem cells to manage Peyronie's Disease in humans," says Dr. Zahalsky. "We're thrilled with the early results from the study, and look forward to continuing research on this evolving field of urologic biologics."



First Stem Cell Study for Peyronie's in Humans Shows Promise -- CORAL SPRINGS, Fla., Oct. 8, 2015 /PRNewswire/ -- (http://www.prnewswire.com/news-releases/first-stem-cell-study-for-peyronies-in-humans-shows-promise-300156415.html)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lucketts on October 13, 2015, 10:51:10 AM


Thanks for the update.  Exciting news.  Please post anything else you find on this subject, as will I.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on October 16, 2015, 09:09:00 AM
That is for sure the most exciting news I saw in this forum. I have sent an email to zurology.com about their treatment. Lets see what they say. Thank you a lot!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: krazylord on October 18, 2015, 09:44:56 PM
Hi All,

This is very good news. This is my first post on here, so hi to everybody :)

I am a bit confused though as to whats the difference between this stem cell trial done by Dr. Zahalsky and the one that Dr. Irwin Goldstein is doing in San Diego with stem cells + PRP. Does anybody knows the details?

Thanks a lot!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Dared on October 20, 2015, 03:17:30 AM
This is great guys! I'm only 23 so there's a good chance I'll see something like this become a reality before I'm dead.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: ao210021 on October 23, 2015, 11:38:26 PM
What we also need to do is write a letter to the Japonese Urological association.

Japan just passed a low for reducing the time it takes for regenerative medicine therapies to be offered to patients. It only take 3 years I believe now (the fastest in the world).

Their goal is to become a medical turism destination.

There are 48 stem cell trials in Japan right now but not a single one on penile tissue engineering. The reason is that not many Japonese suffer from this.

I believe that if all of us sent a letter to Japonese researchers they will see the benefit and start clinical trials in this area as well.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: lukewill on October 25, 2015, 11:06:01 AM
Have you guys not read about the progress that's being made elsewhere with stem research

Florida Urologist Publishes Exciting Results of Stem Cell Treatment for Peyronie's Disease

check this out:

Florida Urologist Publishes Exciting Results of Stem Cell Treatment for Peyronie's Disease (http://www.prweb.com/releases/2015/10/prweb13007884.htm)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Pfract on October 25, 2015, 05:10:26 PM
everybody by now on the forum must have read about that, but the opinions vary. Thanks for showing the link though. Time will tell if this is just some other quack therapy, as james normally calls it.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Dared on October 26, 2015, 01:56:09 AM
Seven of ten plaques disappeared... pretty amazing. How long does it generally take for a treatment like this to be made available to the general public? 5, 10, 20 years?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: krazylord on October 26, 2015, 06:25:15 PM
I've talked to Dr. Zahalsky and I am quite convinced stem cells will be the next treatment for Peyronies Disease, better than Xiaflex and others that we've seen. Also for ED, but this will more effective the younger is the patient. He uses amniotic SC and PRP and saw a lot of benefit.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on October 27, 2015, 03:19:43 AM
I'm young, 25, but I don't have a plaque, just diffuse fibrosis. I wonder if it will be useful for me too.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: krazylord on October 27, 2015, 07:18:30 AM
Hi Jack,

I have both, and believe it helps with both, yes. Currently there are many studies, mainly for diffuse fibrosis and nerve damage in the corpora, but Dr. Zahalsky is ons of the first ones to do it directly into plaques as well. I think stem cell help in both kind of fibrosis.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on November 02, 2015, 10:48:18 AM
Why don`t you guys go there? I just called to his office. It seems that they are doing the treatment already... I am trying to buy some to do the application in Brazil with Paulo Egydio. Unfortunately I expired my visa in 6 months while I lived in US, so I don`t think I will be able to come back so soon :-/
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on November 03, 2015, 03:10:26 AM
Istme, what Egydio think about that?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on November 03, 2015, 02:45:00 PM
So, I just came back from there.
He told me stem cell need to be yours, which I didn`t understand, because we see every day about amniotic liquid stem cell being used in everybody. He told me he has used it in a guy on my age (27) from belly fat, that didn`t work (but he didn`t give me more details about how many times was done and for how long).

He prescribed me two ointment that I will put the name here. I needed to take another injection to get erect for the exam, which I am very traumatized of. The other doctor Isaw before, gave me a lot of pentoxifylline injections that didn`t work at all too.
I have been taking magnesium, pentoxifylline, carnitine and vit e by myself, which seems to be helping. I am doing exercises and eating very well too. He prescribed me colchicine again and told me to not eat green stuff for helping to hold the medication and avoid diarrhea. He told me to do traction pulling my dick every day six times for 3 to 5 minutes.

I would like to see more people here doing the stem cell treatment.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on November 03, 2015, 02:53:36 PM
But I need to say, he seems to be a very honest person. It didn`t look like he is doing that just for taking others money at all.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on November 04, 2015, 03:19:33 PM
The name of the ointments he prescribed in Brazil are:
Contractubex
- cepalin 100mg/g
- alantoína 10 mg/g
- heparina sódica 50UI

Postec
- hialuronidase 150 UTR/g
- valerato de betametasone 2,5 mg/g

He told me to put it and after wrap my dick with that transparent plastic that we use for food.
He also told me to do traction pulling my dick 6 times/day for 3 to 5 minutes each time.
I started to take Colchicine again as he asked me for. I hope to not have diarrhea that much again :-/
As I told you guys another time a lot of people in my family had it, but I am the only one who was taking finasteride, I hope my case will not be worse than them because of that. All of them had a normal life: my grandpa, his brother, sun and my cousin (was born with it). My grandpa from mother.
I think I got it while sleeping in a nocturnal erection :-(
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: kuaka on November 06, 2015, 09:46:56 AM
"pulling" is ok, as long as it is not excessive.  It is one aspect of "reshaping".  Pulling just hard enough to feel tension on the plaque...affected area of the tunica...is all you want.  My opinion anyway.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on November 08, 2015, 05:41:25 PM
I don't understand why he gave you these 2 oinments...to reduce fibrosis?
how many times per day do you need to put them?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on November 10, 2015, 02:03:42 PM
Contractubex at night and Postec during the day. I don`t think it is to reduce the fibrosis. I believe it is to put an end in the inflammation phase, but I am not sure though, that is what I understood or believe.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on November 10, 2015, 02:06:46 PM
I have seem some of you guys telling about real stem cell. What does it mean? And which studies are with expanded stem cell to some specific tissue and which noes are not? I believe by the results I have seem here, the ones that are done with pure stem cell without make them the three specific tissues are needed aren`t worth to.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Dared on November 20, 2015, 12:50:07 AM
Can someone pleas explain to me why this treatment is not already available? Does the fda have to approve it? And how long do you think it will be before it is made available?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hof1988 on November 23, 2015, 09:06:55 AM
To all gents dealing with Peyronies or Ed due to penile injury...

Has anyone on this forum been to the Zurology Clinic?

The clinic provides a "Placental Matrix derived Mesenchymal Stem Cell Treatment" 

I would like to know if anyone has tried this treatment with success



I did contact Dr Zahalsky and know this about the treatment:
1)  Injection cost $3,000
2)  Uses Ultrasound to Guide Injection to Plaque
3)  He is in Florida, but also works with physicians in Chicago who can provide the injections. 

Here are the links regarding the stem cell treatment he provides:

https://www.auanet.org/university/abstract_detail.cfm?id=PD22-01&meetingID=14ORL

https://clinicaltrials.gov/ct2/show/NCT02395029
















Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on November 23, 2015, 07:28:07 PM
It is actually available. Just zahasky's clinic. Please, let us know the results if u take it ;-)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on November 24, 2015, 05:07:48 PM
there were already many clinics who offered them, for example a clinic in California, but the results were poor. I hope the reason is the unproper machine to purify the fat tissue. I believe they must be 100%pure and the harvest of fat tissue should be massive to be really effective
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on November 27, 2015, 05:08:57 AM
But zahalsy told he got 100% results in many tests. Or he has this machine or he is lying. I think the big diference is about cell diferenciation. They should harvest, increase the number letting them multiply, diferenciate them in diferent tissues, three I believe, and then inject it. Maybe Zahalsky is doing that...
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lucketts on November 27, 2015, 10:16:14 AM


Dr. Zahalsky may be on to something very big.  But it would sure help if they would be more forthcoming and informative in exactly what they are doing, how many patients have had it, the rate of success etc.  It's hard to undergo these stem cell injections just on a doctors sayso that they work.  Don't think FDA approval is needed for stem cell injections if they come from your own body.  But would be nice if NIH could do some clinical trials w/ stem cells vs. a placebo group.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on November 27, 2015, 07:00:50 PM
Quote from Lucketts
QuoteDr. Zahalsky may be on to something very big
You mean very big on the medical field, to help the sufferers, or very big in filling up his bank account? 8)
Sorry for my cynical sentence above, but I will not take seriously that he is telling he had 100% results but no any clinical trials.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Pfract on November 28, 2015, 12:28:49 AM
I am with James on this. I hardly believe there lots of truth in this doctors opinion...
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hof1988 on November 28, 2015, 10:49:23 AM
Let's start a go fund me account.  We all donate $100 for one person to try the treatment at Dr Z. and than they report their results on here.  I'm fine with taking a $100 hit opposed to $3,000. 

Also, he does not use Adipose Stem Cells like California.  He uses Placental Stem Cells, but where he gets them from I don't know.  This would be something good to find out... his clinic is connected with UroStem which may be the supplier. 
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: kuaka on November 29, 2015, 06:54:32 AM
Unbelievable claims are exactly that.  If he really is on to something, it will become apparent over time, but I would not get too excited just yet.  We so afflicted are prime targets for snake oil as we are willing to commit mucho dinero to fix this.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Pfract on November 29, 2015, 09:45:33 AM
That's what's happening in some posts i read, kuaka. Snake oil treatment believers.... But to some extent i understand. People try to think positive things about treatments which are not going to solve their problem. Like this stem cells for example...
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on November 29, 2015, 10:05:46 AM
I am the first to be skeptical about my future, but there is no reason why I and we have to post our pessimism over and over again as some members do here. I understand, some in here have been suffering for decades and they do not believe in anything anymore. But this not obliges us to bring other new members/new suffers down, who, luckily, will have a cure in a couple of years. Just not post if you think there is no hope from here to the next 1000 years. Hope is important and people who spread pessimism are useless.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on November 29, 2015, 03:59:09 PM
About Zalansky, I read from his presentation that one patient got Priapism after 6 weeks and he developed a new small plaque.
Do you know how much an injection costs?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on November 30, 2015, 07:44:29 PM
Exactly. If the guy is just a big lyier he woudnt post about this priapism guy. Egydio told me that stem cell should be from ur own body though. So I dont understand this amniotic stem cell then...
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: kuaka on December 01, 2015, 08:45:35 AM
Stem cells are of basically 2 kinds.  Mature body stem cells are available to become essentially anything in order to replace damaged cells.  These are made in your marrow.  These are not quite as malleable as embryonic/amniotic ones though, so the reduced effectiveness of them being "foreign" is countered by the increased effectiveness of them being "new", as in "part of the process of building a human body from scratch".

My daughter is currently receiving stem cells from both her own marrow and amniotic from the baby she lost during her liver treatments.  She is basically getting a liver transplant at the cellular level, and they have her on as much anti-rejection medicine as an organ recipient...but that is unrelated here...but is why I'm informed on the stem cell thing.

The balance of how much better the amniotic cells are at becoming healthy Tunica vs their rejection potential from not being "you" is the question in this case.  I'm not sure what the answer is, but stem cell therapy/transplantation is still a new field of medicine.  Only time will tell.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on December 01, 2015, 11:29:53 AM
So, will we collect money for someone to test Zahalsky treatment or not?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on December 01, 2015, 11:36:38 AM
These are the testimonials about him: https://www.zocdoc.com/doctor/michael-zahalsky-md-32753
It doesn`t seem he is a liar.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on December 01, 2015, 05:02:18 PM
isteme

Your link is to a pure commercial site, it is not allowed on the forum.
If I was a moderator, was deleting it immediately and giving you a warning!!!
Regarding testimonials, how many you want regarding the miracles of the snake oil? or any subject for this issue
I can write many in a hour if someone will pay me for that.

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on December 04, 2015, 12:04:45 PM
Actually it doesn`t have any advertisement there. It is a testimonial website that allow you to schedule an appointment with the doc. Maybe there are some fake testimonials there, but for sure it also has true testimonials, since there is even people complaining there...
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on December 04, 2015, 04:39:28 PM
amniotic stem cells can seriously lead to cancer if taken from umbilical cord. Adipose derived are much better but you need to purify them before injecting, and this is the biggest problem
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lucketts on December 05, 2015, 11:51:53 AM


I find the link by itsme very helpful.  It's simply the standard ZocDoc (very reputable) that describes the doctor.  It shows that he has a pedigree educational background, and that he has published a large number of articles.  As I've mentioned in a prior post, he was also accepted for a presentation to the SE section of the American Urological Association. I have to think that this group would aggressively vet a doc and his presentation before allowing him to speak.

IMHO, all information is good information on products, doctors, etc., and I've never understood why this forum is so quick to delete such information.  I for one have no problem with anything descriptive or promotional -- followed hopefully by member comments on whether it's real or just BS promotional.  I think that I and the other forum members are wise enough to tell the difference, and if its BS, the post will die a quick death. Don't know that moderator censors need to make those decisions for us.  Regarding patient reviews and testimonials, sure there are ringers out there.  But my experience when I look at doc reviews, is that the ones I like have mostly good reviews, and the ones I don't, tend to have negative reviews.  Don't think that most docs have the time, inclination or lack of ethcis to pay and play w/ reviews.

I also agree with the post about not being cynical, being optimistic, and keeping an open mind to new techniques.  But back to Dr. Zahalsky. His approach is unique in the peyronies field, similar to Dr. Morganstern's.  His patient reviews are mostly positive, but a mixed bag.  I wish that he would put his technique through the rather expensive and time consuming clinical trials, so we could see verifiable and objective findings.  Almost all stem cell treatments for the body are on the cutting edge, and outside the NIH/mainstream world.  But time will tell.  Let's hope  it works.  It would be nice if Dr. Z could participate in this Board, and be subject to questions by its members. Is it possible for the moderator to contact him and see? And BTW, my suggestions about censoring less are meant to be constructive.  I am ever mindful and grateful for the time and money spent by the folks running this board. It is such a great resource when living in the lonely world of peyronies.

                                                     Lucketts

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on December 05, 2015, 05:05:09 PM
Lucketts

Unfortunately I am not moderator so for your knowledge I can't censor nothing and no one has censored Istme post.
As no one censored nothing so why it was necessary to post:
QuoteBTW, my suggestions about censoring less are meant to be constructive

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: LWillisjr on December 05, 2015, 09:26:29 PM
Quote from: Lucketts on December 05, 2015, 11:51:53 AM

IMHO, all information is good information on products, doctors, etc., and I've never understood why this forum is so quick to delete such information. 
                                                     Lucketts

Actually I think we pride ourselves on not deleting member's views and opinions no matter how abstract. James is correct in that the link has not been deleted.

We we do look down on are those who come here and try to sell something. We do delete links to sites that try to sell something that we don't agree or support simply to guard those from chasing the easy solution. And we do ban new members who come here trying to sell something. There is nothing easy about Peyronies.

We'll see if this thread dies on its own.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on December 07, 2015, 09:22:56 PM
There is no way to doubt about stem cell treatment for peyronie after seeing these videos: Stem Cell Patient Video Testimonials (http://stemcelltreatmentnow.com/patient-videos/)
The center is in Thailand. It seems that Asians are far way from the US in this matter.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on December 08, 2015, 09:55:30 AM
We find nothing at Wake Forest website :-/
Just this video about surgery:
Wake Forest MedChannel: Peyronie's: The New Fix for "Bent out of Shape" (http://medchannel.wakehealth.edu/videos/peyronie-s-the-new-fix-for-bent-out-of-shape)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on December 08, 2015, 10:49:06 AM
Zahasky research is in all serious websites: peyronie stem cell - PubMed - NCBI (http://www.ncbi.nlm.nih.gov/pubmed/?term=peyronie+stem+cell)
I wish I was american to get it done now.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hof1988 on December 08, 2015, 11:01:29 AM
Quote from: itsme on December 08, 2015, 10:49:06 AM
Zahasky research is in all serious websites: peyronie stem cell - PubMed - NCBI (http://www.ncbi.nlm.nih.gov/pubmed/?term=peyronie+stem+cell)
I wish I was american to get it done now.

If the link below is the company Dr Z orders his cells from, it may be easier and more affordable just to order the cells yourself and inject the cells the same way someone would inject caverject.  Why pay someone a couple grand just for simply doing an injection. 

http://arthrogenix.com/225-2/
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on December 08, 2015, 12:11:36 PM
What is this ArthroGenix – DX100™ (http://arthrogenix.com/225-2/) link for? I didn`t get that? I didn`t find anything over there about Peyronie`s...
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on December 08, 2015, 02:17:41 PM
Hmm, I see now, they sell it: ArthroGenix – Placental Tissue Matrix Therapy (http://arthrogenix.com/services/)
But why do you think Zahalsky is buying it from them? Thank you!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hof1988 on December 10, 2015, 12:40:57 AM
I emailed Dr Z at Zurology asking where his clinic is purchasing the Placental Matrix Stem Cells from.  But before anyone here gets overly excited, you must read this post from Regenexx.

Regenexx offers regenerative medicine treatments for ligaments and tendons.  I've been researching regenerative medicine for 7 years and Regenexx is legitimate.  Based off of their research Placental Tissue Matrix products do not contain living cells from the companies products that they researched. 

Amniotic Fluid Stem Cells Pros and Cons: More Scams... - Regenexx® (http://www.regenexx.com/amniotic-fluid-stem-cells-pros-and-cons-more-scams/)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on December 10, 2015, 11:27:34 AM
About Zahalski

How many injections should a patient do to get results?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on December 10, 2015, 08:55:47 PM
Here are the links to his study:
http://medrebels.com/wp-content/uploads/Peyronies-Paper.pdf
http://zurology.com/wp-content/uploads/2014/05/AUA-Presentation-ED.pdf
http://zurology.com/wp-content/uploads/2014/05/URO-StemAbstracts.pdf

3 injections for 3 months and then 1 per year for a while.
Specialists in Brazil are saying that some else`s stem cell wouldn`t work without a immunosuppressive remedies, which seems to be complicated. And these studies don`t say anything about immunosuppressive remedies. But it is also true that a lot of patients benefited from the stem cell treatment in China (Stem Cell Patient Video Testimonials (http://stemcelltreatmentnow.com/patient-videos/)).

I get all these critics about stem cell, but it is a fact that some people are being cured with them. If we use verapamil and these other things that is more than proved that don`t work, why not to give it a try? He are some other links of my research:

Jeff Blank - Ataxia - (He says some stuff about how the stem cells are done I think)

Transplante de Células-Tronco Hematopoéticas (TCTH) - ABRALE (http://www.abrale.org.br/pagina/transplante-de-celulas-tronco-hematopoeticas-tcth)

IPCT – Instituto de Pesquisas com Células-Tronco (http://celulastroncors.org.br/conselho-consultivo/)

http://www.celulastroncobrasil.com.br/Contato

Wake Forest Institute for Regenerative Medicine (WFIRM) - Wake Forest School of Medicine (http://www.wakehealth.edu/WFIRM/)

Wake Forest MedChannel: Peyronie's: The New Fix for "Bent out of Shape" (http://medchannel.wakehealth.edu/videos/peyronie-s-the-new-fix-for-bent-out-of-shape)

http://uroweb.org/wp-content/uploads/16-PenileCurvature_LR.pdf

Has Anyone Been To China Or Thailand For Stemcell? - Spinal Cord Injury Research And Surveys - Quadriplegic and Paraplegic Spinal Cord Injuries (http://www.apparelyzed.com/forums/topic/13960-has-anyone-been-to-china-or-thailand-for-stemcell/)

About SCN - Stem Cell Network (http://www.stemcellnetwork.ca/index.php/about-scn/)
http://www.stemcellnetwork.ca/wp-content/uploads/2014/07/2014-2015.pdf

Stem Cells and Adult stem cell injections for Peyronie's - Peyronies Society Forums (https://www.peyroniesforum.net/index.php/topic,1001.msg71643.html#msg71643)

Zurology offers "Placental Matrix Derived Stem Cell Therapy" for Peyronies & ED

https://www.youtube.com/watch?v=53lCRy2aMaY 8:32

-------
The rocky road to regulation : article : Nature Reports Stem Cells (http://www.nature.com/stemcells/2009/0909/090923/full/stemcells.2009.125.html)
Stem Cells Fraud Scheme in U.S. Leads to Arrests (http://stemcellstm.alphamedpress.org/site/misc/News010.xhtml)
Stem cell tourism poses risks (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273527/)
The Cell Peddlers | Dealing Hope To Desperate Families - Reaching for answers (http://www.jsonline.com/watchdog/watchdogreports/83179987.html)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on December 10, 2015, 09:24:30 PM
There is no way to read this study http://medrebels.com/wp-content/uploads/Peyronies-Paper.pdf with all this data and think it was all invented. For me the biggest prove this is not just a scam is when you see the list of doctor involved in the study (Effects of Stem Cell Treatment in Human Patients With Peyronie Disease. - PubMed - NCBI (http://www.ncbi.nlm.nih.gov/pubmed/26414724))
Effects of Stem Cell Treatment in Human Patients With Peyronie Disease. - PubMed - NCBI (http://www.ncbi.nlm.nih.gov/pubmed/?term=Zribi+G%5BAuthor%5D) (1 research)
Error encountered - PubMed - NCBI (http://www.ncbi.nlm.nih.gov/pubmed/?term=Iorio%20L%5BAuthor%5D&cauthor=true&cauthor_uid=26414724) (134 researches)
Error encountered - PubMed - NCBI (http://www.ncbi.nlm.nih.gov/pubmed/?term=Marchand%20M%5BAuthor%5D&cauthor=true&cauthor_uid=26414724) (334 researches)
Error encountered - PubMed - NCBI (http://www.ncbi.nlm.nih.gov/pubmed/?term=Levy%20JA%5BAuthor%5D&cauthor=true&cauthor_uid=26414724) (552 researches)
Error encountered - PubMed - NCBI (http://www.ncbi.nlm.nih.gov/pubmed/?term=Zahalsky%20MP%5BAuthor%5D&cauthor=true&cauthor_uid=26414724) (six researches)

People say that Beike Biotech in China is a scam too, but the fact is that a lot of people went out from there seeing, and they were almost completely blind before...
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on December 11, 2015, 06:48:40 PM
istme

What is the reason to fill the topic with those "Error encountered - PubMed - NCBI"?
They are all giving "History not found"

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lucketts on December 12, 2015, 01:29:36 PM


Haven't read the web sites, but here's the little I know about Dr. Z.

a.  I think he owns the stem cell place which creates whatever he injects. 

b.  Regenexx is one of the leading providers of stem cell remedies.  I think they are located in Boulder.  In most major cities, there are just a handful of physiatrists (orthos dealing in pain management) who use stem cell for knee arthritis, bursitis, rotator cuff problems etc. I don't think that any of the Regenexx approved physicians are using it for peyronies.............yet.  I have heard urologists say that it could be helpful post-surgery for those who go that route.

Regarding Dr. Z, does anyone know any of his patients or does anyone have references from any peyronies patients who have actually been through his work?  He may be on to something extremely good, but it would be really helpful if he could be more transparent.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on December 16, 2015, 10:27:52 AM
Look at this video about Regenexx, it doesn`t seem to be a fake company: https://www.youtube.com/watch?v=reYnA3KukvM
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on December 16, 2015, 11:10:26 AM
There is another guy here also saying about stem cells for peyronies: Stem Cell Therapy: The Future is Here! Find Out About the Clinical Tr... (http://www.slideshare.net/PatientsMedicalNYC/stem-cell-therapy-the-future-is-here-find-out-about-the-clinical-trial-and-how-you-can-be-a-participant)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on December 16, 2015, 03:08:42 PM
It seems that Zahalsky company actually buys stem cells from this one: Skye Biologics - White Papers (http://skyebiologics.com/resources/white-papers)
I mean, there are links to this company in the end of the page ArthroGenix – DX100™ (http://arthrogenix.com/225-2/)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on December 29, 2015, 11:35:27 AM
so, nobody is gonna try it? I mean zahalsky's injections. If I was rich I would try it.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: itsme on January 08, 2016, 09:27:06 PM
I have sent an email to skye. They told me they are really selling stem cell to some doctors for peyronies treatment.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Pey-penis on January 09, 2016, 04:11:34 AM
From what I know about stem cells from a patient, who had such treatments is that if you use "foreign" stem cells must take steroid immunosuppressive drugs for life. In Poland developed technology "manufacturing" stem cells from the patient's own cells and then it does not require the use of drugs but somehow the matter was muted :(. I'm trying to iontophoresis ionic colloidal silver, which is said to have properties to reset DNA of material building scars, which take DNA from the surrounding the cells . This is important at the initial stage of the disease when is the healing of damaged tissue.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: krazylord on January 09, 2016, 04:36:37 AM
Hi Pey-penis,

I have seen studies in rats and humans, both, of placental stem cells (foreign stem cells), and no steroids where necessary.

I think that you should make a difference between embryonic and amniotic from placenta or umbilical cord.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on January 09, 2016, 07:36:43 AM
Iontophoresis is completely useless, the drug does not pass, it's a scam.

Dr Zahalsky told me that you don't need immunosuppressant at all, but I doubt it. we'll see
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: krazylord on January 11, 2016, 11:29:13 PM
What do you guys thinkg about the fibrosis that the stem cells injections create? Apparently Dr. Z injects not only in the plaque, but also in both corpora chambers. If an injections goes to the corpora, there is no doubt that is going to create more fibrosis, since it is gonna disrupt and break penile tissue.

So I am wondering if it is worth it to try, since the risk of creating more fibrosis is high.

Any opinions?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on January 12, 2016, 05:01:23 PM
it goes into the corpora only if needed. And how can you say that an injection in the corpora would cause more fibrosis? It is not true at all. it depends on what you inject.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: krazylord on January 12, 2016, 08:21:57 PM
Hi yyy,

I don't know if it is the injection or what you inject what causes fibrosis, but my doctor told me not to use penis injections for instance for ED because they can create more fibrosis.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: yyy on January 13, 2016, 04:15:17 PM
yes maybe they could, but it's not sure. if you inject pure stem cells you could have good chances to improve the corporal fibrosis
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Pey-penis on January 14, 2016, 07:15:12 AM
Quote from: krazylord on January 09, 2016, 04:36:37 AM
I have seen studies in rats and humans, both, of placental stem cells (foreign stem cells), and no steroids where necessary.
My friend had a spinal nerve atrophy and received stem cell treatments in clinical trials. He does not know what cells he got but the problem was getting settled, but must take immunosuppressive drugs for the rest of his life.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Pey-penis on January 14, 2016, 07:19:21 AM
Quote from: yyy on January 09, 2016, 07:36:43 AM
Iontophoresis is completely useless, the drug does not pass, it's a scam.
If You think so this thought  think so forth and go far :-(
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on January 14, 2016, 10:33:07 AM
Pey-penis I don't know what are you talking about. The entire and new field of regenerative medicine is based on your own cells and that means you do not have to take immunosuppressive. Tissue engineering the same.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: krazylord on January 14, 2016, 12:39:50 PM
Jack, Dr. Zahalsky uses Placental stem cells, meaning they are not yours cells. He might be referring to that.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: krazylord on May 06, 2016, 09:48:44 PM
Just to correct myself. Dr. Zahalsky doesn't use stem cells. He uses amniotic fluid from placenta, but he does not know if there are actual stem cells there or not. He only knows that there are growth factors and cytokines. That's all. So all the studies where he claims to use stem cells are just a fantasy and a marketing lie, unfortunately. I am very disappointed on that. Claiming to use stem cells when he does not even know if they exist is insulting.

That being said, it looks like many of his patients are seeing good results. In my case I didn't.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lucketts on May 06, 2016, 11:16:27 PM


Krazylord,

Disappointing.  I know he says that he used to use stem cell, but switched to this amniotic fluid (really don't have much idea what either is).  On his site, he has some testimonials with the first names of patients.  Did you ever see any more substantive proof that his process worked -- research papers, trials etc?

                          Lucketts
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: krazylord on May 07, 2016, 12:54:14 AM
Hi Lucketts,

To be honest, I am not sure he never really used stem cells at all in the studies he published. Once you discovered a doctor is not honest in the way he advertise his treatment, then I don't believe anything else, even if it is true.

His research papers mention placental stem cells: Effects of Stem Cell Treatment in Human Patients With Peyronie Disease (http://jaoa.org/article.aspx?articleid=2445317). Again, given that I found out he doesn't (I asked myself directly to him) use stem cells currenty, then I don't know about this study (unless he used something different from his current procedure). I will ask him this specifically, and get back to you.

I have seen the testimonials in the website, and they are great. Now, he has treated more than 100, as far as I know, so that is just 5%. Still, some cases good. I am not saying it doesn't work, just disappointed by the doctor not being 100% honest with his claims. When you go to his office, he has papers talking about his "stem cells" procedure, and again, he doesn't use them. That is outrageous.

The main difference between amniotic fluid and stem cells is the cells. In the amniotic fluid you have basically proteins and growth factors, that might trigger your own stem cells to repair your damage. Stem cells on the other hand would not need to call your own since they are already stem cells. Nobody really knows how stem cells work, but what I want to find out is if he EVER used stem cells and now doesn't, or f he used it in the study and now it doesn't.

THanks,
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lucketts on May 07, 2016, 10:12:28 AM


Krazylord,

Thanks for the explanation.  When I had spoken with him, his explanation was something about that he found that when he used stem cells, it spread and dissipated through the body, so I guess it didn't stay local, and that's why he was no longer using it.  But please let us know any further information that you find out.  I remain hopeful that there will be some new discovery that will be our long awaited cure.  Bit off topic, but you might want to look at the NIH web site.  I think it is is NIH.org or something like that.  It shows all the NIH clinical trials going on for peyronies, and one of them is w/ botox.  Maybe that could be the salvation -  perhaps get a straight dick (and no wrinkles to boot).

                                Lucketts
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Dumbguy on June 05, 2016, 09:41:20 PM
Just adding a bit, im around 3.5 monts whit a hourglas injury, i will be taking maybe next week a shot whit around 10 cc adipose derived mesenchymal stem cells plus prp, and after that 4  prp 10 cc shots one each 2 weeks
hoping for the best  :)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: krazylord on June 05, 2016, 11:11:56 PM
Hey dumbguy,

Can you share with the community where is this, which doctor, and details like that?

Also, and I am sorry for the questions, but this will benefit everybody, some questions here:

- Is the hourglass effect present in semi-rigid and erect, or only in one of both?
- Do you have an hourglass with a clear plaque explaining it, or is it just the hourglass and you cannot feel any plaque arund the shaft?
- Will the Doc inject the ADSC ONLY around the tunica around the shaft? Or will it inject it in the Corpora Cavernosum? Or both?

Also, could you share pictures of your hourglass in the photos section?. It would be nice to see a before and after picture. Of course, this is totally up to you, but it would help our data of objective treatments (positive or not).

Thanks a lot.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Dumbguy on June 06, 2016, 12:46:48 AM
Puebla, Mexico. The name of the doctor is Jenny de Jesus Ayala Certero (G.P), the total cost Would be around 1900 USD
remember this is mexico, so the price would be the wage of around 6 months of an average or little above average worker
well i am not that sure on how bad is the progression at this time. The plaque does feel in flacid and erection, its not fully hardened but its hard for sure, last weeks i´ve been noticing retraction in flaccid and erection, i am almost feeling healthy then i try to use ved and i F~@< up again (thats been around 3 or 4 times), despite my efforts to be cautious ved just F~@ks me and i think has provoked me more injuries, i have not yet a penile extensor but just pulling it 40 min a day has made me see a nice difference whit retraction, nice nice difference this last days
also i have some ed i have no morning woods but i can F~@< so not sure where i am
and well doc sais will put all the liquid in my penis she can whit a high high high concentration of stem cells and less prp so she can fit more of it inside, and the rest will go intravenous. She also will send me to some radio frequency therapy that she sais has helped her get rid of most of fibrosis she had from a recent lipo where they use hyperthermia and after that the radio. I think its the hyperthermia the one working. Well i will try to take photos but im not sure if i will be capable to achive a full erection now as i am i a new, new, new acute stage atm.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Dumbguy on June 11, 2016, 07:23:48 PM
Hey!

I´m really excited and i hope i keep it this way, i really do

It´s been around 3.5 hours since the last stem cell injection, it was 10 cc prp plus 10 cc adipose derived stem cells, the procedure was a lot less painful or even bothersome than i expected. still i think the doctor was a little less hygienic or even ethical that other clinics (she attended a cell phone call during the lipo, and after the lipo was attending other patiens as her asistant (wich also seems to be her maid) did all the centrifugation and filtration proces), also im still having my doubts on how well she knows to inject a penis. Anyway you get what you pay for and well i think it well worthed it and if not she sent me some cyprofloxacin just in case lol.

So after all the process the injections begin and i think it was gonna be just like the other things, more bark than bite but i was wrong
it did hurted a lot, more the stem cells, it lingers, so anyway it was around 20 shots all over the penis  and my penis turtled to 4 cm or so, it was horryfing, and there was a time when i thought i f'~c<+d it i just f'~c<+d it this was an awful idea but well i continued the shots as more than the half wasnt still injected
oh another detail she tried fastening me a elastic ribon to provoque me a erection but erection was not posible
well my penis looks now a lot wider and the hourglass is a lot less noticeable im honestly really happy for have it done, some of it must be inflamation but she injected a lot and some of it must have sticked

i feel really hopeful :D

sorry guys i forgot to take a photography of it before, but have some of the procedure
god bless us all


Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on June 14, 2016, 12:24:30 AM
Dumbguy

Wish you success with the treatment, update us how is the progress

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: rich68 on June 14, 2016, 09:57:37 AM
Thanks for the update Dumbguy, this is good to hear. I wish you continued good luck.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Dumbguy on June 28, 2016, 11:39:53 AM
its been a long time for me, maybe its relatively little, today i feel kinda hopeless

well first i have to say i was 5 days whit no pentox before injections and that around  7 cc of the stem cells prp coctail were injected in the new lession, the rest were in other parts of the penis however its suposed they travel to the injury no?, anyway, i couldnt have an erection that day. so maybe it reduced its efectivenes
i was almost ok before i could have erections, damn hard erections despite it was difficult to get it hard, but once hard it was hard so i decided to stretch a little that lost size whit a VED and i f'~c<+d up more. I think im now getting a bottleneck insted of a hourglass on the top of the shaft
now its just fuuuuuuuuuuuucking hard to get an erection, retraction and hard flacid were restarting.

something maybe interesting is that the hourglass felt flacid on the flacid state
but later i noticed in fact all that lenght was inside if i pull it the hardness is there
maybe it will take months untill i see some progress, im hoping so
anyway i have gotten back since 2 days ago whit pulling my dick cause it had shown some promising results, but this time as more time as passed its harder to get the same results
i had some big succes whit hiperthermia those good times
so im getting back to manual stretching, hiperthermia and im getting a male edge extensor this week, im determined to do 5 hours a day
i feel if i do nothing now im just F U C K E D

i will cease prp following injections by now
if stem cells dont show much promise i just dont see the point on prp

hope to have better news some months later
whit love dumbguy
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: popopo on June 28, 2016, 06:22:58 PM
Hey man, thanks for keeping us updated. Do you think you might be overdoing it with the VED and traction? If you let the shots do their work now you can tell if it really works or not. Maybe the extra stress slows down healing. For me it doesn't work anyway, but I know it helped others so maybe you can let it heal from the shots first and then try again with the VED and traction. I hope you'll see results either way.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: kuaka on June 30, 2016, 01:32:45 PM
VED and traction both are mixed bags.  Undue stress on the original fibers of the Tunica is one of the reasons for this disease in most cases.  Scarring develops as the body's way of healing a wound. 

The objective any treatment is to remove the scar tissue which impairs erection and replace it with something less restrictive which still maintains the outer bounds provided by the Tunica in a naturally functioning penis.  Without this outer bound, excessive engorgement is quite possible, AND it is this outer bound which results in erection.  The classic case of Peyronie's is where this outer bound has been bunched up by scar tissue.

Remove the scar tissue, and VED/Traction therapy with a great deal of caution is appropriate.  The purpose of the VED/Traction therapy is to prevent the tissue from bunching back up.  Providing adult stem cells so that the body has something to work with beyond normal scarring processes is not a bad idea, but still bringing the penis up to fill size often during the healing process is important.  Overdoing it can just cause additional scarring and make things worse.  It is a tight rope walk no matter how you look at it.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on July 06, 2016, 01:45:50 PM
I still not believe we have nothing better than technologies from seventies..that's embarrassing. I'm so angry I can't accept that my life has been ruined like this I have no peace...we are at the dawn of 2017..
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Dumbguy on July 09, 2016, 05:18:26 PM
Hey
Just reporting back
i have a good new, my "gf" told me some days ago my dick is bigger in erection, i also think it does looks wider.
before treatment, even before manual traction the fibrous band seemed hardened and... well now it does looks different in the flacid state is like a hard flacid but more widespread and  mmm not sure it varies i think that i would have gotten more injury of the lasts ved tries whitout stem cells, my gf also sais is longer but not as when we met (before i had bad peyro).
as i said i really did thought to get into hypertheermia now that colagen is not as dense, but i read hypertermia kills stem cells so i decided i will wait till 3 monts after the shot to get back to it.
anyway im in traction right now, androextender, really carefully.
for personal complicated" reasons i ve been overusing my dick this week whit sex, and it feels sore and inflamed but i will be taking a rest of one week full at least.

welll, somethimes i feel hope sometimes i feel its just delusional

but well my gf sais it is bigger, and it should be progressing, so i know they worked but do not know how much will it last

end of this report
ah guys what did i get myself into, F^@$!ng jelquing exercises and bad using of ved

thanks for your suport, and i really hope i have better news for us all soon
stay safe, take care.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: popopo on July 10, 2016, 02:56:13 PM
Yep jelqing is horrible. And I also talked about it on some of those forums but they actually get offended when you warn them. I feel like a lot of these forums are scam and it seems that moderators benefit from keeping people dumb and will use everything to ban negative review. The harsh reality is that it will eventually be positive for us. I imagine loads of guys will hurt themselves doing jelqs and they will later join us and bring a cure for peyronies and maybe a legit way of enlargong the penis closer to us.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Dumbguy on July 10, 2016, 10:16:21 PM
yo, i know dude, my life at this moment could be so great, but well im stuck in here
have you read about  the penuma penis enlargement implant?, is a silicon sheat under and around the penis that for what ive read works the same as traction, eventually the penis gets the size of the sheat and its permanent as it´s silicon. it was FDA aproved this year and is performed by dr elist
i dream to get one of em, and after that another one
im starting to break down mentaly
so much F^@$!ng frustration and fear

dude life is hard
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Dared on July 15, 2016, 03:09:00 PM
just checked out the implant you were talking about and it looks pretty cool. I would consider getting this as a last resort.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on July 16, 2016, 02:27:31 AM
Dumbguy

Can you guide us to the FDA approval?
Quoteit was FDA aproved this year
Make a search on the forum regarding Dr. Elist and see what forum members wrote about him
His forum name is drelist, you may want also to read his posts:
https://www.peyroniesforum.net/index.php?action=profile;u=12155

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: popopo on July 16, 2016, 05:45:52 PM
I've looked into dr.Elist's iimplant too and I wouldn't risk it. Even without peyronie's there's a risk of scarring and I've read a lot of horror stories about it. I'm still curious how many people actually improved their sexlife with it, but so far it doesn't seem like a very good option.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: FriskyDingo on July 16, 2016, 06:38:53 PM
A quick google search of dr. elist implants and you will find some legitimate testimonials and comments pointing to another forum. The testimonials and comments, which seem genuine, do not speak well of Dr. Elist at all. I would highly recommend research him further.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: nowhereman on July 17, 2016, 08:02:34 PM
In the penis enlargement world the name Elist is synonymous with the word BUTCHER. An understatement if anything. The word Sociopath could be added.
Reconstructive surgeons have made lots of money from repairing this guys handiwork, as well as the work of others. I don't think I've seen a single positive review. At least ones that were actually real.
-That implant is no good.
-FFT will resorb into the body
-Lig cuts will only gain someone flaccid length, and you can be left with a nasty scar..

I think gaining .5-1" is possible for length if one really works at stretching, Cutting the ligs won't help, It's not generally something people say they would do again if they could go back.

The least invasive method for permanent girth gains is a filler like PMMA, there have been some success stories/pics, but there have been many semi-negative/negative ones as well (mostly aesthetic problems like nodules). Though, nothing like the horror people who have had Elist operate on them. The best forum for this just started charging to see certain parts of the forum, If they didn't do that I could have showed you guys a great example of an Elist implant gone wrong. Dudes dick looks like a chewed up dog toy.(after reconstruction with the best in the world.)

The best option for girth gains is expensive at this time, and not permanent, but that's the best thing about it (IMO). It's the filler Hyaluronic acid. It is injected in the dartos like PMMA, but if there are problems, or nodules form you can just inject an enzyme that makes it go away immediately. I think it usually lasts a couple years, but obviously gradually starts going away long before that. I am not interested in any of this but for peoples safety I just wanted to throw out the REAL options. I wouldn't want anyone going to the maniac "Butcher of Beverly Hills".

Here is that forum I mentioned before:
PhalloBoards (Version 2.0) (http://phalloboards.websitetoolbox.com/)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Dumbguy on July 23, 2016, 08:58:49 PM
yo, i know we are getting off topic but i found this: https://www.youtube.com/watch?v=BlYPAt2KtgM

lately i think due to andropenis i have been experienced increased ed (ZERO response)
so im in lose lose desicion making scar retraction and poor function or zero erectil function and retraction for atophy. hope i have still time to rethink cause i could have worked better whit some function but now...
i will be going to see a good andrologist in some days.
so im planing and praying caverject will get it hard and flexible for the time needed to convince my dad to pay for any implant.
im not covered by insurance and he would have to sell the property that was supposed to be my heresy, however ive read so many stories and dude, this is already going downhill just faster and faster.
anyway interesting procedure (video), i think ive heard those second names in the forum once.
i doubt a lot i can get that one made but i would be glad if that could help anyone and maybe be real or good
my mental sanity is geting lost sometimes
dont know what else to do. i know this is already off topic.
btw i found a paris stem cell human performed work that sais its until the 3 months when cells stop growing but honestly i already have lost fait on it.
im reading your post on psychological distress and ed, sometimes it helps
before i had some hopes whit neov method but now it just doesnt seem to work i mean it doesnt inflate minimally
i really pray caverject helps



Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on August 01, 2016, 01:40:26 AM
Both Dr Franklin Kuehhas and Dr Egydio are well known and respected surgeons, including in this forum
Please do not compare them with Dr Elist!!!

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Dumbguy on September 10, 2016, 11:13:32 PM
well 3 months after the procedure, progresion still happening (my penis is narrower (cone) and shorter(1/2 inch))  and i still feel inflamation, sometimes i have good erections, sometimes i have 0. it depends on if i do traction or dont, if i dont i get better erections but i  feel shorter

to consider:
i used pentox tratment 3x500 5 days before the treatment
i used some heat treatments during those 3 monts

sorry guys, i am still hoping i was injected whit a scam and real stem cells work

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: DELETED on October 01, 2017, 02:01:25 PM
Any news&updates for stem cells clinical trials&treatments?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Paolo on November 23, 2017, 03:29:55 AM
Guys, looks like stem cell research still continues;

Inhibition of penile tunica albuginea myofibroblasts activity by adipose‑derived stem cells

https://www.spandidos-publications.com/etm/14/5/5149



Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: popopo on November 23, 2017, 09:50:38 AM
Sounds good, I might stick around to see this happening one day. I just hope I can regain my interest in women again without feeling angry and feuatrated when the day comes I dont have to feel that way anymore.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: TonySa on November 23, 2017, 03:26:28 PM
Nice to hear this gives you hope popopo 😎
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on November 23, 2017, 06:40:51 PM
Gives me hope also, but at 70 I don't know if I will be around enough time for this treatment :)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: swiss on November 24, 2017, 07:20:52 PM
Quote from: Paolo on November 23, 2017, 03:29:55 AM
Inhibition of penile tunica albuginea myofibroblasts activity by adipose‑derived stem cells

Paolo, can you explain this to me in lamens terms I can understand? lol.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: kuaka on November 24, 2017, 08:09:50 PM
just pick it apart...

Inhibition = reduction/prevention
penile tunica albuginea myofibroblasts = fibrosis lumps on the tunica
adipose-derived stem cells = a particular stage/type of stem cell reflecting its ability to become something else

Using this type of stem cell reduces or prevents additional fibrosis lumps on the tunica.  Sounds good to me.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: swiss on November 24, 2017, 08:49:55 PM
You so smart bro. Thanks!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Paolo on November 25, 2017, 06:15:12 AM
Cheers kuaka  :)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: LuvWhiteSand on December 13, 2017, 04:26:40 PM
Has anyone heard about or tried Dr. Landers stem cell therapy in California?
His website claims to use 3 forms of treatment in the process:

SHOCK WAVE TECHNOLOGY- Provides deep tissue energy that breaks up the Peyronies plaque
STROMAL VASCULAR FRACTION- Contains adult stem cells and growth factors (signaling molecules) derived from fat tissue. This may provide anti-inflammatory and regenerative effects on the abnormal corporal tissue.
PLATELET RICH PLASMA Contains additional enriching growth factors (signaling molecules) which are obtained from a person's own blood that is processed with a centrifuge.

I have seen this type of treatment work successfully with people who have Knee issues... but haven't seen or heard of any results for peyronies.

Thanks,
Mike
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on December 14, 2017, 08:06:53 AM
I don't know about the first two treatments, but the third one is just PRP.
We have just one forum member, maybe two that got good results.
You can read the PRP related topics

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: PeetyPeet on December 14, 2017, 11:33:41 AM
Of these three only Stromal Vascular Fraction uses stem cells and could be considered 'stem cell therapy'.

According to Wikipedia, the nominal stem cell is the Mesenchymal stem cell. It can differentiate into several tissue types, but apparently it is quite inefficient. Currently there's no research that demonstrates its effectiveness.

With the exception of the liver smooth muscles tissue of most organs cannot regrow well, if not at all. Alas, I'm not optimistic about this treatment. I also fail to see how the regrowth of tissue would remove an already existing fibrotic plaque.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on February 01, 2018, 03:06:02 AM
(Repost, if it's too much take my thread in the main forum down.)

Hello all. I will give a more formal introduction of myself in the new member area in a few days; I am currently deeply absorbed in Peyronie's research and will not stop until I've read everything I need to. For a brief overview of my case, you can check my comment in Neo's youtube video here: https://www.youtube.com/watch?v=ypvCSSCnmq4

I just wanted to link to something I saw recently on the Joe Rogan Experience. Mel Gibson and Dr. Neil Riordan were guests, and the topic of discussion was Stem Cell Therapy, specifically using IV infusion of "day zero" umbilical cord cells donated to the clinic. It is located in Panama, as that is currently illegal in the United States. Umbilical cells are different from embryonic cells, in that they are apparently more effective and less dangerous. They are essentially "super" stem cells; most are the age of the patient at time of extraction, and umbilical cells are literally "day zero." Watch the video if you really want more info. The part I'd like to highlight, however, is Mel's story of his father. At age 92, his father could barely walk and was on the brink of death. Out of desperation, Mel brought him to Panama and his father received direct injections into his hips, as well as an IV infusion of umbilical Stem Cells. His father, now age 99, can walk and is thriving. Interestingly there were some collateral effects too: he regrew some pigment in his hair, his eyesight improved, and he found great improvement in erectile function.

This is very promising to me. I'm currently on the verge of receiving stem cells for a torn meniscus, cubital tunnel hydrodissection of the ulnar nerve in the elbow, and wrist tendinitis. I would consider adding on Peyronie's treatment and flying out to Panama for it. Here is the link: https://www.youtube.com/watch?v=OtL1fEEtLaA

Here is the exact part I'm talking about: https://youtu.be/OtL1fEEtLaA?t=8m27s but I highly suggest watching the entire video.

Here is the link to the clinic in Panama: https://www.cellmedicine.com/ Apparently they treat Autism as well, and with success, along with a multitude of other disorders. Amazing stuff.

I'll be posting again soon.
-JS
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Paolo on February 01, 2018, 03:18:40 AM
That is very interesting indeed if true  :-\
Will drug companies quash this kind of research as if true they are going to lose tons $$$. Medicine runs on controlling conditions, not curing them so you become a dependant/consumer.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on February 04, 2018, 09:46:02 PM
Doctors in the US are already using stem cells for erectile dysfunction.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: bummedout on February 10, 2018, 03:16:59 PM
https://www.ncbi.nlm.nih.gov/m/pubmed/26414724/

I'm assuming someone has posted this already, but in case they haven't here it is.  Has anyone heard of anymore trials?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on February 11, 2018, 11:44:51 AM
Quote from: Christopher1 on February 04, 2018, 09:46:02 PM
Doctors in the US

@Christopher1: can you mention which doctors you know of?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on February 11, 2018, 10:06:43 PM
pey ron, Dr. Landers in California is one: Lander Regenerative Urology | Certified Diplomat of the American Board of Urology (http://landerurology.com/)

I'm currently considering application to this institute in Manhattan: Stem Cell Therapy | Stem Cell Transplant | Stem Cell Transplant Therapy | New York - Park Avenue Stem Cell, NY 10075 (http://parkavenuestemcell.com/)

There are several more, just google it.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: bummedout on February 11, 2018, 11:42:16 PM
JS1991,

How do you know these places are legit?  Did you read the fine print?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on February 12, 2018, 12:24:35 AM
bummedout, Lander has been doing the procedure with mixed results for years. You can read about it in the earlier pages of this very thread. Regarding the Manhattan clinic (and any other for that matter) I personally look into reviews for the clinic and each and every doctor I can find that works there. So far so good; the only red flag I've seen is that they seem to be apart of a bigger network of Stem Cell centers, similar to Regenexx. This actually might be a good thing in terms of quality, not a good thing in terms of cost. Regardless, they are the only people in New York (my state) who offer specific Peyronie's treatment with a Urologist on site, so it is worth looking into. I plan on contacting them soon.

Regarding fine print, it doesn't really matter. Stem cells are an effective treatment that is still in its infancy. Therefore, I understand the inherent risk involved. Nonetheless I believe in the treatment, and as long as I can get a reputable doctor to apply adipose-derived stem cells directly to my plaque, I'm taking the best chance I can. I'm willing to accept failure in the stem cell department, to be honest; I just can't accept not going through with the procedure when I have the means to do it.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: TonySa on February 12, 2018, 11:57:20 AM
Any idea what they charge for the stem cell injections into the plaque?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on February 12, 2018, 01:21:46 PM
I had called one of these networks and they said 10000 dollars.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: bummedout on February 12, 2018, 03:07:00 PM
JS1991,

I look forward to hearing about your results.  I was under the impression that stem cells have not yet been successful in treating most conditions.  Hopefully your experience will be different.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on February 12, 2018, 08:21:55 PM
Our own member, rd, "cured" himself with stem cell treatment applied by the aforementioned Dr. Landers in California: Peyronies Gone - Peyronies Society Forums (https://www.peyroniesforum.net/index.php/topic,5144.msg58014.html#msg58014) . Contained within that link are literally his last posts on this forum; apparently he no longer needs it.

For more on his story, read the first few pages of this thread. I'm hopeful myself because my own injury occurred the night of January 19th, so if I get the treatment by the summer I am guaranteed to still be in the early acute phase, which can only be a good thing. I've been controlling the symptoms with traction and heat therapy, along with sexual abstinence (one careful orgasm per week limit). I'm receiving Cialis, CoQ10, L-Arginine and Acetyl L-Carnitine in the mail this week and I have an appointment with a Urologist to hopefully get Pentox in early March (until then I'm substituting with coffee). On top of that I'm attempting to change my diet and I'm also getting a VED soon. I don't think anyone has caught it this early and attempted the stem cell therapy, so I'm looking forward to seeing how things play out.

Aside from that, I have a torn meniscus, cubital tunnel syndrome in the elbow, and wrist tendinitis and I plan on treating these all with stem cells as well. High level athletes and celebrities, and increasingly the general public, use it to regenerate tendons, ligaments and tissues such as an ACL. Checkout this video: https://youtu.be/OtL1fEEtLaA for more info on the topic. Skip to 8:27 for specific mention of ED, but I highly suggest watching the first 8 1/2 minutes as well. It's amazing what can be done in 2018.

I plan on posting a full summary of my own experience (pre-stem cells) soon, but as things are still in motion I'd like to see how it plays out for another week or two before I post. Good luck, everyone.

-JS
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on February 20, 2018, 05:48:04 AM
I found an interesting article; one of the most up to date I've come across in my research. It has 4 recent clinical trial results for ED contained within, all with positive results: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209555/

Also, an update on myself: I received a call from Dr. Landers' office Friday afternoon, but when I returned it they were closed. I plan on speaking with him this week and will report back when I do.

-JS
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on February 21, 2018, 02:19:15 AM
@JS1991: will these be autologous stem cells from your own body or will you need to be on immunosuppressants for the rest of your life?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on February 21, 2018, 09:45:58 PM
pey ron, I'm looking at three options right now, none of which would require me to be on immunosuppressants:

Dr. Landers, California: Shockwave Therapy, PRP, Fat-Derived Stem Cells from my own body. ~$8-10000

Dr. Zahalsky, Florida: Amnion + PRP. ~$3000 per shot (I've heard; haven't contacted yet.)

Dr. Riordan, Panama: Umbilical cord-derived Stem Cells injected locally as well as infused intravenously. ~$25,000 (waiting to see if they will accept me. IV infusion might clear up other issues/injuries I have as well making it very cost-effective.)

Going to Panama for their week-long treatment would be pulling out the big guns in terms of cost and effectiveness. And it would also be a nice vacation. But we shall see.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on February 22, 2018, 03:25:46 AM
do they filter out mutated cells?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on February 22, 2018, 03:56:45 AM
I know for a fact Riordan does, I assume the others do. I will ask when I speak to them.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: TonySa on February 22, 2018, 09:30:16 AM
Peyron, is the tx for ED or peyronies?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on February 22, 2018, 11:37:45 PM
Quote from: Tsanchez12369 on February 22, 2018, 09:30:16 AM
the tx

what is "the tx" ?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: TonySa on February 24, 2018, 05:04:29 PM
Treatment
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on February 25, 2018, 02:31:44 AM
Quote from: Tsanchez12369 on February 22, 2018, 09:30:16 AM
Peyron, is the tx for ED or peyronies?

I think it is for peyronies, but you should ask the people that have looked into it...
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on February 25, 2018, 07:43:29 PM
Tsanchez, yes it's for Peyronie's specifically. They inject stem cells directly into the plaques. They also have treatment for ED, although the Peyronie's treatment should collaterally address both.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Kerze on February 27, 2018, 11:18:06 PM
JS1991, are you referring this one to Dr. Riordan (inject directly into the plaques)? Where did you get the info about the peyronies treatment? I've checked their web page upside down and didn't see nothing about peyronies.

I'm seriously thinking about applying for peyronies and as you put, other minor issues through blood infusion.

Would you please share the info and update your results whit the chosen treatment?

Good luck!!!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on February 28, 2018, 01:52:12 AM
Kerze, I have no idea if they will accept me. I have a feeling they might, just because of the litany of issues I have, and due to the fact that they've never treated it and might be interested in the results. Also, money talks. They require background information like test results in the application, so I'm in the process of going through urologist visits, but unfortunately I probably can't get all of my tests done until early April.
'
In the meantime, I'm in touch with Dr. Landers of California via e-mail, I really need to make time to call him for a phone consultation, since he offered one. I also plan on calling Dr. Zahalsky in Florida as mentioned in one of my recent posts. Once I receive all of my test results for Peyronie's and mild venous leakage, I will submit my application to Dr. Riordan's clinic and give them a call. I can talk well, so I'm hoping to convince them to treat me.

I do have an ace up my sleeve if they don't accept me though. I've decided that I will go to Landers or Zahalsky for treatment, as well as get an additional extraction of either fat or bone marrow stem cells (yet to be decided) for the purpose of storing, multiplying, and eventually being shipped to my house, where my friend who is a nurse can legally administer it to me intravenously. I'm a little crazy so disclaimer there lol. But although it is illegal for doctors to apply stem cells intravenously in America, it is not illegal for me to pay to get mine extracted, multiplied, then shipped to me on ice for whatever I so choose. Here is a video explaining said process: https://www.youtube.com/watch?v=mUNrr_eJP-Q skip to 10:41 for the exact information. It's being featured in Men's Health magazine. There is a video of him actually doing it if you want to google it. The entire thing is worth a listen though.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Kerze on February 28, 2018, 01:37:40 PM
Thanks JS1991!

Indeed, the only reason Dr. Riordan won't accept your application is for lack of expertise in peyronies treatment. However I do think they might have an urologist in their staff to assess this particular case.

I will start to fill the application in order to know what background info they need it, so I can begin to collect them all (already have the medical report for peyronies).

I'll keep following your results closely. Good luck mate!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on February 28, 2018, 09:24:58 PM
Quote from: Kerze on February 28, 2018, 01:37:40 PMHowever I do think they might have an urologist in their staff to assess this particular case.

This is precisely what I was thinking. Regarding tests, I believe an ultrasound workup that shows the plaques, if any, as well as the test that shows blood flow (cavernosography? forget the names) if you have any form of ED from the Peyronie's. This coming Tuesday (March 6th) I'll be going to the urologist and getting a Peyronie's diagnosis; I believe Dr. Riordan would need a full workup of plaque locations to know where to inject, etc. Good luck!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on March 06, 2018, 08:53:27 PM
Update on my own situation: I saw my urologist today, and got my Peyronie's diagnosis in written form. That's step one completed. At this point I'm being referred to a Peyronie's/ED specialist that will give me all the tests necessary for the clinic I choose.

Speaking of which, I spoke with Landers' office in California. It's $150 for a phone consultation, which is scheduled. I plan on proceeding with this, just to get that conversation out of the way. Also planning on contacting Dr. Riordan soon. Will update when I do!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on April 09, 2018, 04:00:28 PM
Bump.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on April 14, 2018, 04:02:18 PM
Hey Christopher1, here's an update: I also need a stem cell injection for my torn meniscus as well as Peyronie's, so I'm juggling my options between:

US Stem Cell Clinic, Florida (~$15000 combined): Stem cell injection into penis, knee, iv infusion (stem cells from my own fat). I also have $500 off if I use them because I applied via the Ben Greenfield promotion.

Stem Cell Institute, Panama: Hopefully umbilical cord injections into penis and knee, as well as infusion. Possibility they will make me go to the RMI in Texas for my knee, also possible they won't be able to do injections into the penis in Panama; will find out within the month but I consider this the best, most expensive treatment option. (~$25000)

Landers Regenerative Urology, California: Injections from my own fat into the penis (~$8000). I would need to get my knee done elsewhere and wouldn't be able to get an IV infusion. I do believe, however, that Landers is the most experienced and has the best technique when it comes to the application of injections into the penis.

Overall, I'm leaning toward the US Stem Cell Clinic in Florida. I have a very big decision to make here and I want to make the right one. I'm finishing up all my testing as I research where to go; just got an ultrasound on my bladder, kidneys, and a urine test. Still need a blood test (mainly for hormone levels) and then finally an ultrasound on my penis to show plaque location/size and blood flow. Will update when I'm closer to a decision; I plan on going for the stem cells in late May or June.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on April 15, 2018, 09:04:56 PM
Very big decision indeed.

I, too, plan on using stem cells for the penis. The reason I am waiting is because I am currently a resident physician and pay is not great as a resident. So I am waiting on becoming board-certified, working my butt off, and then getting the stem cells.

Please keep us updated. I, too, will report my results on this forum when the time comes. We are in this together!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: DELETED on May 01, 2018, 06:39:42 PM
Any news&updates?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on May 06, 2018, 08:05:06 PM
Bump.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: ed2018 on May 24, 2018, 09:16:41 AM
Saw this, Anyone know anything about these guys or is it just rubbish ?
Thanks !

https://www.prnewswire.com/news-releases/caverstem-adult-stem-cell-therapy-for-erectile-dysfunction-receives-positive-reception-at-international-urology-conference-300653752.html
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on May 25, 2018, 02:43:51 AM
Don't know if it's effective or not but it's clear that we entering a time with new options.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: ed2018 on May 25, 2018, 06:05:09 AM
ok Thanks Jack1909
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on May 26, 2018, 04:15:56 AM
An update: I've been in contact with several clinics over the course of the past month, and depending on how my phone consultation scheduled for June 5th goes, I believe I am going to go with US Stem Cell Clinic. My main concern is whether they will be adding PRP with the cells, as well as if I can get shockwave therapy along with this treatment. US SCC is also going to be supplying me with an IV infusion of my own cells on top of it all. I feel the Stem Cell Institute in Panama is a bit expensive for me at the moment, and I'm better off using my fat while I'm young, as the cells are biologically aged at date of extraction (I'm 26); umbilical cells (which they use in Panama) are day zero and I can always use them down the road. I'm getting an ultrasound done June 14th and I expect to get the cell procedure done soon after, hopefully before the 4th of July, but I don't know how soon they can get me in; I'll find out on the 5th of June. I'm also considering supplementing down the road with amniotic fluid injections via Dr. Zahalsky if necessary. I will update after my consultation.

Also, CaverStem uses bone marrow, which I am using on my knee; I believe fat-derived cells are better suited for penile issues. But that article is excellent news!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on May 26, 2018, 11:26:22 AM
Awesome news!

I am also going to try this. Please keep us updated!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: ed2018 on May 27, 2018, 05:16:14 PM
"Also, CaverStem uses bone marrow, which I am using on my knee; I believe fat-derived cells are better suited for penile issues."

JS1991
Thanks
Good to know
And best wishes to you
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on May 28, 2018, 11:44:56 AM
Hello guys, i have got a question for JS1991:

I don't speak english perfectly, so i'm not sure that i understood well.
You're taking part of a new developmental treatment with stem cells, right?
I read about something REALLY promising here:

https://www.ncbi.nlm.nih.gov/pubmed/26414724?dopt=Abstract

Is this the treatment you're going to do? When are you going to do it, and can give us some news? Thank you very much, let's keep in touch.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on May 30, 2018, 08:03:24 PM
ed2018, thank you for the well wishes.

hope794, I am going to be getting stem cell treatment, yes. Read through the previous posts in this thread and you will be able to read more about my efforts. I have been updating this thread since January, so no worries, I will be here.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on June 02, 2018, 09:30:52 PM
Okay. = )
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on June 05, 2018, 05:29:30 PM
So, I just had my phone consultation with the US Stem Cell Clinic in Florida! The lady on the phone (Kelly) was very nice and answered all of my questions. Overall I'm pretty happy. Here is what I've gathered:

They do offer injections directly into the penis for erectile dysfunction, and they have had a small number of patients come for Peyronie's. The treatment involves drawing some blood and two mini lipo-suction procedures, followed by injection same-day into the plaques of both stem cells AND PRP. They also have experience with other connective tissue disorders such as Dupeytren's, I'm told. The treatment for the penis is $6,000, with the option for an extra $3000 of adding on additional extraction of fat cells for same-day IV infusion, with the rest going to a cell bank ($250 per year to upkeep), which will be culture expanded providing a total of about 25 treatments that I can literally get mailed to my house whenever I want for whatever I want, including additional penis injections. These are also going to be 27 year old cells (I'm turning 27 this month) that can be re-injected into my older body in the future. In addition to this, I can get my torn meniscus taken care of for an additional $1000. Normally this would be much more expensive, but since I'm getting everything bundled up, and I got $500 off with the Ben Greenfield promotion, the total cost of meniscus repair + Peyronie's treatment + stem cell IV + banking = $9500.

They do not offer shockwave therapy in their treatment, but recommend it and referred me to a clinic in NY. Christopher1 has a great at-home alternative that I might just do instead. I can also get this stem cell/PRP procedure done in as little as 2-3 weeks from now (July 18th marks 6 months that I've had Peyronie's; I'm still in the active phase so this is great news). Overall I'm very happy, I was expecting to pay about 50% more than what I was quoted. The only downside (in my opinion) is that although they have done many procedures for ED, they have done only a handful for Peyronie's, so the technique when injecting into plaques may not be as good as someone like Dr. Landers who has done this procedure hundreds of times (although it is $300 just to speak to him, and this consultation was free). I am luckily getting an ultrasound by my uro on the 14th, so I assume that will help guide them.

Lastly, there is a clinic on Long Island that is associated with US Stem Cell, which I am going to call this week. If they quote a similar price range, I might get it done there to save money on flights and hotel. If not, I'm probably going to just fly to Florida by the end of the month. We shall see, I will update soon!

Edit: I forgot to include this: https://www.youtube.com/watch?v=H4T6WReGPro&feature=youtu.be which is a video they linked me through email featuring what they do.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on June 05, 2018, 06:42:38 PM
JS, thanks for keeping us updated!!! So, you're going to do all this treatments in 2-3 weeks?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on June 05, 2018, 07:58:49 PM
No problem! If all goes as planned, I will be doing this all in the same day at the end of June, yes. I'm also considering adding on treatment for some herniated and bulging lumbar discs that I have.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on June 06, 2018, 04:16:31 AM
I wish you the best, JS1991. You're doing something great: sharing your experience with us and keeping us updated, even when you'll get cured. I feel this is going to be a succeed.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on June 13, 2018, 04:40:04 PM
Update: I'm officially scheduled for treatment on Tuesday, June 26th. I just need to order my plane ticket and book my hotel room and I'm good to go! The day of the procedure I will be updating this thread quite a bit. Final cost: $6,000 for Peyronie's, +$1,000 for torn meniscus, +$3,000 for IV infusion and cell banking, -$500 for applying through the Ben Greenfield promotion = $9500.

Edit: I might also try to get a single treatment of shockwave therapy in New York a few days before I fly down to Florida to help break up the plaque and cause a bit of inflammation (which will help the stem cells).
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on June 13, 2018, 05:18:35 PM
JS1991, thank you very much for keeping us updated!!!

P.S.= Update your personal diary too, and read the PM i sent you  ;D

I wish you the best, sincerely. You give us a great motivation!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on June 15, 2018, 02:51:19 AM
I got an ultrasound done today, and my urologist (who is great by the way) did not see any plaques, although he acknowledged a broad area of the shaft felt thickened. My erect curvature I've actually managed to get down to 5 degrees from 15, as measured by a protracter. My uro, who scoffed at my alternative treatments such as Pentox and traction at first, admitted that they perhaps have contained my plaques thus far.

Regarding stem cells, my uro told me to do what I want, but specifically mentioned avoiding Dr. Zahalsky, who he knows personally. He said Zahalsky uses amniotic fluid which has "growth factors" and no actual living cells, and is therefore similar to a PRP shot.

To conclude, I'm hoping that this treatment I will be receiving reduces the thickness of my plaques, or erases them entirely. We shall see!

Edit: This is the official readout of what I'm receiving, as stated on the form I must sign:

Blood Draw & Adipose Extraction
Platelet Rich Plasma and Adipose Derived Stem Cell Isolation
Intravenous Injection of Adipose Derived Stem Cells Suspended in Saline
Joint (Knee) Injection of Adipose Derived Stem Cells Suspended in Platelet Rich Plasma
Penile Injection of Adipose Derived Stem Cells Suspended in Platelet Rich Plasma
Cell Banking
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on June 16, 2018, 03:29:26 AM
@JS1991: I wouldn't say the name of your uro given he'd not have advised you against a doctor he knows in person had he known that you would have posted it on a public forum indexed by google... I think you could remove the name of your uro and keep the advice to avoid Dr. Zahalsky.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on June 16, 2018, 05:46:33 AM
pey ron, You're completely right. I just edited my previous post, thank you very much for the heads up!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Tony52 on June 17, 2018, 08:56:00 PM
Thanks so much, JS1991, for keeping us all posted with such thorough and complete information.  It is greatly appreciated.  I wish you all the best as you pursue this treatment.  I will definitely be following your progress posts.  Good Luck!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on June 25, 2018, 02:58:31 PM
Thank you for the well wishes! My flight leaves in 3 hours, so the next time I post I'll be in Florida, post-procedure. Expect a detailed summary of my experience tomorrow afternoon.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on June 25, 2018, 07:14:48 PM
@JS1991 Good luck bro!!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Tony52 on June 26, 2018, 12:52:39 PM
Good Luck, JS1991!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on June 26, 2018, 04:45:14 PM
Hello everyone! I just got the procedure done, and it was a lot easier than I thought it would be. The most uncomfortable part of the procedure was the mini liposuction but even that was more discomfort than pain. The clinic was nice enough to give me a free shot of PRP in my uninjured knee (that has recently sustained a minor injury) so I'm very happy about that.

The penile injection didn't hurt, and there were no issues even though I have hard flaccid. My penis is swollen at the points of injection, which I expected, but there is no pain. I was instructed to abstain from sex and masturbation for a week, which is good because I began NoFap (PMO) Saturday, so I'm already 4 days strong abstaining. I plan on continuing to abstain for as long as possible. So, altogether not a bad experience. Now the waiting game begins, so I will update as frequently as possible on my penile status.

If anyone has any questions, feel free to ask!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: suicidecomingsoon on June 26, 2018, 05:01:54 PM
Edited sorry, I just saw the price
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on June 26, 2018, 07:17:08 PM
JS1991, i'm really happy for you. How much time did the doctor say that you have to wait before seeing results? and for how much time should you see results? i remember that RD said that, after 1 year, he was still seeing some changes..
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on June 26, 2018, 08:48:56 PM
hope794, I actually didn't ask for specifics on how long it will take. The clinic I went to doesn't specialize in Peyronie's, more erectile dysfunction and joint related injuries. Personally, I'm going off of what RD said, and I'm also using joint injuries for reference. Joint injuries usually heal with stem cells starting from a week out going all the way through to a year out. I was told they have had success treating Dupeytren's contracture, which is a connective tissue order almost identical to Peyronie's that affects the hand. I was also told they have some guy from Silicon Valley with ED that flew out to treat it, and now gets his banked stem cells sent to him in the mail ($500 per dose, very concentrated, kit included) and he actually injects repeat doses into his penis himself, apparently with success. That is not something I would do, but I could always ask my uro or a local stem cell clinic to do it for me (not saying I will need it, but they're so cheap I might as well).

I was also told they have someone calling from Italy inquiring about stem cells for Peyronie's, could that be you, friend? Lol
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on June 27, 2018, 04:41:07 AM
LoL, i think that it's probably me. I'm famous now.  ;D
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on June 28, 2018, 05:11:04 PM
I just had my follow up call with the clinic (I wasn't able to speak to them yesterday because I was mid-flight back to NY), and was able to ask about a timeline on progress. They said that anytime before or up to the 6 month mark I should be seeing results, all the way through to a year, and as soon as this month.

I'm also debating just shooting my banked stem cells into my own penis, since it's only $500 per dose to get my banked cells shipped to my house on ice with a full kit for same-day use. This is extremely cheap therapy, considering these cells are culture-expanded in the lab and therefore contain a far higher count of autologous mesenchymal stem cells than the stromal vascular fraction I received. I can also do this for my knees, IV therapy, anything. Men have been known to be given injections to take home with them to induce erection in certain cases of ED, so it's not that far-fetched of an idea.

Unrelated to stem cells, I plan on trying a 7 day water fast to reset my system and relax my muscles, hopefully relieving me of my hard flaccid and pelvic floor tension, as well as fully refilling my glans/cs. This will be accompanied before and/or after with a full ketogenic intermittent fasting diet (props to NeoV and his amazing YouTube channel for the suggestion!), as well as trigger point therapy and stretches for my pelvic floor. I've also completely quit smoking weed or consuming THC in any fashion (smoking kills stem cells and I wanted to take a break anyway). I've been having dreams all week for the first time in about 10-15 years, it was pretty interesting. Apparently you don't dream when consuming marijuana daily.

No one can say I'm not doing literally everything in my power to fight this damn condition(s)! Haha.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on June 28, 2018, 06:51:46 PM
I wish you the best JS1991! Keep us updated, thank you for your contribution.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Gabriel on June 29, 2018, 07:15:07 AM
Same here : Thx a lot JS, all your adventure is fascinating, you are undoubtedly THE figurehead of Peyronie's empirical research in the world!! We will follow your progress from very close, so don't hesitate in posting a lot :-).

Regarding marijuana, yes I can testify that it prevents you from having dreams (or at least remebering them). Personnaly, I almost totally quit a year and half ago, and feel much better.

About fasting and ketogenic diet I'm not sure it can help, but I did not try it very seriously though; anyway I'll be on IF all summer as usual (first time with Peyronies Disease), and will keep you up to date about any progress we could attribute to this protocol.

All the best to you JS!!!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on June 29, 2018, 08:48:48 AM
Guys, trust me: DON'T SMOKE MARIJUANA.
It lows testosterone and other androgen hormones. They are ESSENTIAL for peyronie.

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Werther on July 03, 2018, 05:31:54 PM
Quote from: JS1991 on June 28, 2018, 05:11:04 PM
I just had my follow up call with the clinic (I wasn't able to speak to them yesterday because I was mid-flight back to NY), and was able to ask about a timeline on progress. They said that anytime before or up to the 6 month mark I should be seeing results, all the way through to a year, and as soon as this month.

How is the treatment structured? Are you going to get injected twice a year?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on July 05, 2018, 04:29:03 AM
Werther, the treatment included the injections I received on the 26th, as well as banked cells that I can use as early as August. For $500 I get a cultured (higher concentration of MSCs) adipose-derived batch of my own stem cells delivered to my doorstep on ice for same-day use with a kit including a syringe and saline solution to dilute. I plan on self-injecting into my penis and bloodstream every two months until I'm out of the acute phase. I could pay extra to have a doctor apply the injection, but I figured why not just do it myself; doctors give take home medications to inject that produce erections for certain patients with ED.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: lukewill on July 05, 2018, 04:42:47 AM
Wow this thread has been going on for three years. Seems like you're a bit of a pioneer here. Have you noticed any changes in the few days since treatment ?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on July 05, 2018, 04:54:57 AM
lukewill, the swelling has gone down completely and I have no adverse side-effects thankfully! I had what I would describe as a small grain of rice on either side at the injection sight towards the tip of my penis, although one was not embedded in the tunica; it was literally floating between the skin and penile tissue. I think it might have been clotted blood or something, not sure, but it is completely gone now.

Regarding results, well, I don't have any evidence other than feel and look, but my penis seems like it got a little bit bigger. Feels heavier, thicker and longer. I will need to measure my penis again, which I haven't done in a long time. The last time I measured I was exactly 7 inches, and I didn't measure girth, but this was in January when I got the disease. I ordered a tape measure that should be here by the weekend for this purpose, but I do want to note that I have been applying traction to my penis pretty much daily since shortly after I got the disease in January. This could definitely have added length, although it wouldn't explain the slightly larger feeling penis since last Tuesday (it has been about 8 1/2 days). Again, there is no proving it is not in my head since I don't have precise written record of length and width, but I do feel as though it is slightly larger. Luckily, I will be keeping written record of size from this weekend and on, including after my future injections. And one more time, these results (in the long term) could be slightly clouded by traction therapy, which I believed had added slight length prior to these injections.

I'm hoping that these injections prevent calcification and reverse girth loss in the tip of my penis as well as the slight curvature I have (5 degrees erect, although it varies when flaccid). I plan on reporting back to this thread once a week for an update, as well as answering any and all questions you guys have for me in between my updates. If all goes well I have pictures since day one to prove everything I am saying too, if it is necessary to produce them.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: lukewill on July 05, 2018, 05:09:10 AM
Thanks for the reply. I think the penis does always seem heavier after injections in general. For example like with xiapex as effectively the penis has had a small vile of substance injected into it so until it dissipates it will make the penis feel heavier. I haven't read through all the posts yet as there are so many but what was your curvature like before or I guess now, and what were you told might be likely outcomes for reduction ?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on July 05, 2018, 05:21:05 AM
No problem! I was at about 10-15 degrees at the beginning, but I'm down to 5 degrees erect at the moment from manual traction. Keep in mind I caught this very early and have been applying traction daily since literally the first week of my Peyronie's symptoms. I do, however, have varying curvature in semi-flaccid/flaccid state, and as my penis fluctuates between soft flaccid and hard flaccid it will sometimes "curl up" in the direction of my curve temporarily. I hope to contain all of this and prevent it from affecting my erect penis; I heard flaccid symptoms are a sign of things to come in the erect penis. I also hope to stomp out this hard flaccid with fasting and trigger point therapy before my next injections, but that is a tall order. I'm trying my best.

I wasn't given exact likely outcomes for reduction, per se; this clinic that I went to does not specialize in Peyronie's, I just picked it because of the banking and their ability to treat my joint injuries as well as provide IV infusion, on top of the penile injections. If it were just my penis I was getting treated, I probably would have gone to Dr. Landers in California, who has way more experience treating Peyronie's with stem cell/prp injections, and provides shockwave treatment before hand. He does not bank cells, however.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on July 05, 2018, 12:07:36 PM
JS1991,
thank you for updating. I've got a couple of questions for you:
1. Did you suffer from ED?
2. Did you have a plaque or a fibrosis?

Both if you have plaque or fibrosis, did they say that stem cell would get rid of it?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on July 05, 2018, 10:49:23 PM
No problem! I have slight ED, but it is mainly caused by chronic pelvic pain syndrome. The symptoms of my ED are slight sensation loss along the CS/glans, which also don't fill with blood all the way (cs/glans = underside of penis/head of penis). I do have fibrosis in the top third of my penis, it has a "rougher" feel to it than the rest of my penis and is tighter and thinner, with the curvature coming from the worse side (the left side).

I also have a dent right under the head on the right underside of my penis, where the tissue and the urethra meet. Again, with a rough feeling indent. And upon inspection, it seems as though it is going away, believe it or not. The indent isn't as deep as it was last time I checked it (before stem cells) and the tissue doesn't have as rough of a feeling to it. The only other improvement I've seen since the injections, is in an odd symptom I have where my penis feels like it is almost dividing into three "sections", the left, center (top), and right, with a sort of line forming to separate them on each side. This line/separation seems to be less pronounced than it was.

They said the stem cells should help get rid of it, yes, but this was based on their experience with Dupuytren's contracture, which is identical to Peyronie's only located in the hand. There are, however, accounts of stem cells improving penile fibrosis elsewhere. I will keep everyone updated as things change.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on July 06, 2018, 04:26:09 AM
Thank you, JS1991. You're really kind, as always  ;)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on July 11, 2018, 05:40:45 PM
Here is a week two update: the denting under my penis head on the underside to the right is continuing to show improvement, which I am happy about. I'm actually surprised to see anything happening this early, as most results (as I have learned through research) are typically seen between 4-6 months out. Maybe since it was the only majorly indented spot on my penis, it is filling out with cells, who knows, only time will tell.

In other news, I have learned the earliest I can get more of my stem cells shipped to my house (they are currently being culture-expanded in a lab) is late August. So August/September I plan on self-injecting more cells into my penis, without the PRP. I'll update from this point forward on a monthly basis, aside from any major improvement (in which case I will post), and feel free to ask any questions if you guys want.

Edit: I forgot to mention that I've measured myself for a baseline, and I am still at exactly 7 inches length, with a girth of 5.5 inches at the base, and 4.5 inches at the tip under the head. As far as I can remember, before Peyronie's my penis was always the same girth from base to tip, so I consider that to be girth loss at the tip of an inch. It feels as though there is almost a sheath of fibrosis wrapped around the top third of my penis which has yet to calcify. As you can all see, I am doing everything in my power to prevent that.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on July 11, 2018, 06:23:22 PM
Thank you for updating us!!!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Tony52 on July 17, 2018, 05:31:25 PM
JS1991 -  Thanks so much for taking the time to keep this forum updated on your progress. Personally, I'm very interested in your stem cell journey.  Congratulations on the early improvement that you have already noticed, and I wish you a full recovery in the days/months ahead.  Your determination and commitment to alleviating your condition coupled with your willingness to share your journey is admirable, and I believe you will reap the benefits of your effort while helping numerous others at the same time.  Best Of Luck, and thanks again.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: drew67 on July 27, 2018, 08:44:15 PM
JS1991, for best results I suggest getting your junk in broad spectrum AM sunlight from sunrise until UVB shows up to encourage autophagy, mitophagy, and apoptosis of bad mitochondria using IR and UVA light.  This can also protect you from side effects like oncogenesis
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on July 30, 2018, 01:44:06 PM
Any updates?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: curved on August 08, 2018, 04:17:07 PM
Anyone else other than JS1991 have the adipose derived stem cell treatment?  I tried the PRP without any success and want to see if this is a similar deal.  I had an initial consult and the doctor agreed that PRP would not likely help peyronies but would not be bad in conjunction with stem cell treatment.  It is pricey (quoted $7300) for 3 ESWT treatments and the stem cell injection.  I have tried the ESWT in conjunction with PRP in the past but had to stop because it became quite painful when hitting the plaque. Doc said they would have to give me a lidocaine shot to block pain because the ESWT was essential part of the protocol.  This Doc works with Dr Lander out of California.  Thanks.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Tony52 on August 09, 2018, 03:48:29 PM
Haven't heard from you in a while, JS.  Hope all is well.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on August 09, 2018, 06:46:29 PM
I hope that JS is enjoying his new life - maybe he just wants to wait a while before updating us. I hope that he's improving day after day, and to hear his good news soon.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on August 11, 2018, 05:42:24 PM
Hello all! I did say I would be updating on a monthly basis in my last post from that point forward, so as not to spam this thread every week with posts (and it has been exactly a month to the day lol). I've been trying to enjoy my summer and take my mind off things. At this point, I'm a little over 6 weeks out, and everything is holding steady. Slow improvement in the most major "dent" I have under the head, no gain in length or girth, but no loss either (I've previously lost an inch of girth at the tip over the last 6 months). What I'm expecting out of this is the eventual removal of some scar tissue over time, which can't be done (I don't believe) with traction or VED; those therapies can only remodel existing tissue, not rejuvenate said tissue. This process I'm expecting to take some time. Also unrelated, but my torn meniscus in my left knee feels a lot better after the cell injections, the right knee only slightly better. I have been vaporizing marijuana since getting the cells (which is still a lot safer than smoking), but I will put a halt to that after my next injection and also change my diet.

I will continue to update this thread on a monthly basis. I'm actually going to be receiving a new round of injections sometime in September from my banked cells, I'm just very unsure as to whether I should attempt self-injecting without any training; I could potentially hurt myself. Any advice on that topic is appreciated. It's either self-injection, or pay extra to have a doctor inject it for me. These new cells are concentrated ADSC's, so it's as good as I can get without receiving umbilical cord cells, in my opinion. I'll update sooner than a monthly basis if I make any major decisions, but expect this to be a 1-2 year process before I draw any serious conclusions on efficacy (based off member RD's experience of actual plaques disappearing). As stated in previous posts, I plan on continuing to inject every 3-6 months. I've also decided to go ahead and get a VED while still in the acute phase instead of waiting for the chronic phase, based on some research that I've done. I've also read that stem cells + VED = a good combination. Lastly, I've also got a personal hand-held $30 ultrasound device that I'm going to apply as a substitute for shockwave therapy. And as always, thank you everyone for the well wishes!

drew67, thank you I will attempt to follow that advice!

To the person who said I am pioneering an empirical research-based approach, I appreciate the words!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on August 11, 2018, 07:38:24 PM
Stem cell studies:

A collection of studies on SCs for Erectile Dysfunction by Dr. Tom Lue (human): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209555/

A collection of studies on SCs for Peyronie's Disease (rat and human): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893505/

Zahalsky's study on SCs for Peyronie's Disease (human): https://www.ncbi.nlm.nih.gov/pubmed/26414724

"Expert opinion on biological therapy" for Peyronie's Disease: https://www.ncbi.nlm.nih.gov/pubmed/28274142

Stem cell "homing" with ultrasound (with collection of studies): https://www.fusfoundation.org/mechanisms-of-action/stem-cell-homing

And I'm still searching for that VED + Stem Cell article, will post once I find it.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on August 13, 2018, 05:23:35 PM
Just wanted to update, I measured myself in preparation for VED which I am starting this week. This is the first time I've measured my erect length and girth since about five weeks ago. I'm happy to report that although my length has stayed the same as did my girth at the base, my girth at the tip has improved from 4.5 to almost 5 inches, which is about a half inch gain! I've measured multiple times to ensure that this is correct. That, coupled with the slowly disappearing major dent under my head is promising. I still have all the scar tissue, but I can't complain with those results. Looking forward to starting VED and getting my next round of injections, this time culture expanded/concentrated!

I'll appeal to you all for help once more on something as well: Does anyone have experience self-injecting medication into their penis? It looks easy, just avoid the nerves running along the top and the urethra at the bottom, and stick it in one side or the other at an angle. But without proper training from a doctor, am I taking too much of a risk? I can get culture expanded doses of my stem cells shipped to my house on ice for $500 which is very cheap, and I'd prefer not to have to find a local doctor to pay to do it for me, or fly back to Florida. The clinic even offered to FaceTime with me during my self-injection lol. Any advice is appreciated!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Kerze on August 22, 2018, 12:59:32 PM
JS, I don't think you should try this by yourself. This is your penis you're talking about...a few bucks more certainly will not harm your wallet. I'm literally praying for your recover and I think to the day stem cell therapy is the only treatment that we can put some hope on, in order to get rid of Peyronie's. I've already made my mind about choosing this therapy (intend to do in Panama with Dr. Riordan) but I'm having a really hard time to find a doctor to back me up in Brazil. It seems they think this is some kind of witchcraft or anything but medicine.
Well, I'll come back when I had more info.
Good luck mate!!


Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Gabriel on August 22, 2018, 03:27:37 PM
Hey JS,

I don't bloody know how I missed your recent update on this thread, which I just read: congratulations mate, that is AWESOME results and perspective! Honestly, I don't want to be too optimistic, but if you had a significant girth increase/recover in so little time following your injections, I absolutely don't see how thorough VED and traction could not do further wonders on you. That's all I wish you!!

Keep us up-to-date man, you are the future  8) :D
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on August 23, 2018, 04:16:43 PM
so these results were due solely to stem cells? amazing! How much did it cost so far?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: TonySa on August 23, 2018, 08:49:41 PM
I'd at least have them lead you through the process on skype if they're willing.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on August 24, 2018, 02:50:40 AM
Kerze, Thank you for the advice, I am leaning towards it. I spoke with the Stem Cell Institute in Panama. They specified that they do not offer specific injections for Peyronie's Disease. They told me they could give me a shot in the knee for arthritis as well as an IV infusion for $25,000. I recall you saying you had other issues so it still might be beneficial for you.

Gabriel, Thank you! I am excited to mix all of these treatments together.

pey ron, I would say so, yes. The dent under my head had a very rough feeling to the tissue and dipped in like a bowl, on the right underside where my tunica ends and my spongiosum begins. It now is shallow and feels smoother. There is literally nothing else that I can attribute to this, at least in my mind. Regarding girth, I purposely measured myself before VED and before I restarted oral medication/supplementation (including Cialis) so as not to affect the outcome (you can check my timeline). When I measured myself days after my stem cell procedure, I did it repeatedly, and I repeatedly got a measurement of 5.5 inches at the base and 4.5 inches at the tip. I now measure myself, again, repeatedly, and my base is still 5.5 inches, but the tip is about 5 inches girth. I believe this discounts any possible incorrect measurements, which I was afraid of at first. I've gone through every scenario in my head to possibly attribute these effects to something else because I do not want to give anyone false hope, but this is what has happened to my penis. I'm personally a bit in shock myself, as I've been vaporizing marijuana and even had a few drinks and did not expect to see these results, but they do line up with the 4-5 week out initial estimate of noticeable changes after the therapy. I know I am a bit of a guinea pig here, so there is my testimony. I'm getting more injections soon, so we shall see if things keep improving. I also think getting these injections in the acute phase was crucial. And I further believe that if I combine a round of injections strategically with shockwave therapy, water fasting to induce autophagy followed by a ketogenic diet with intermittent fasting, complete abstinence, Pentox, Cialis, supplements, VED and manual traction, I can rid myself of the disease completely. At least, that is my theory after extensive research. The cost so far was $6,000 for the initial liposuction/blood draw with stem cell/PRP shots, +$3,000 to bank my cells to be culture expanded. I also got $500 off for applying through a promotion, so grand total that I've spent on my penis for stem cells is $5500 if you don't include the IV/banking. At this point we're looking at $500-$1000 per shot depending on if I self-inject or have a doctor do it for me.

Tsanchez, They are willing to FaceTime with me. Penile injection training is a two-appointment process, the first of which they inject you to show how it is done. I've already experienced this when I received an ultrasound, and again when I was injected with stem cells, so that base is covered. The second appointment would be you injecting yourself under their guidance, which I suppose the FaceTime could substitute for. I'm still very unsure what to do, I need to call around and see the closest place to me that can inject and their pricing and I will probably go from there. I'm also considering just going back to Florida as it was a nice little vacation when I went in June, but I have a business to run and it is hard for me to be away from New York. Regardless, time is of the essence here, as I am still in the active/acute phase; I believe I can fit in at least 1-2 more rounds of injections (September and December) before it turns chronic (they must be spaced 2-3 months apart to avoid overload of active cells).
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Werther on August 24, 2018, 08:17:15 AM
Hi JS. If I remember well, you said that you were dealing with some minor venous leak. Did the injection improve it or do you feel like it stays the same, as it was before?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on August 24, 2018, 04:22:00 PM
Hey Werther! What I thought was venous leak turned out to be chronic pelvic pain syndrome/chronic prostatitis, which causes the glans (head) and corpus spongiosum (underside) to not fill with blood completely during erection (as well as hard flaccid). It has not helped those symptoms out at all though, and it isn't caused by venous leakage, so I cant help you with that question, sorry!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Tony52 on August 25, 2018, 01:06:39 PM
Thanks so much JS for all the invaluable information you continue to provide on this forum.  You're helping a lot of people.  My question:  Are you aware of any reported cases where stem cell therapy proved beneficial in the chronic phase?  Thanks.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on August 26, 2018, 09:06:30 PM
Tony52, You're welcome, that is what I always aim for, and is the reason why I created the detailed timeline that I did: to enlighten/help as many people on this disease as possible.

Off the top of my head, I do not. I'm going to have to look back through studies to see if they specify anything. I do know that Dr. Landers has said that there seem to be improved results in patients in the acute phase, but if I'm not mistaken our own member "rd" was in the chronic phase when he received treatment. You can read through the first few pages of this stem cell thread to find out.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on August 27, 2018, 02:24:10 AM
JS1991:

- did they have you sign any informed consent form?
- if so, what risks were you informed of? was cancer one of them?
- how does one get rif of chronic pelvic pain syndrome/chronic prostatitis?

thank you!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on August 27, 2018, 05:04:50 PM
pey ron, I did sign a few forms although I don't recall if any were specifically "informed consent" forms. From what I read as I glanced over what I signed, I believe cancer was mentioned, yes. It also noted that the chance was extremely small, and I did my own research before going in for treatment. The only major cancer case I'm aware of is the famous one where a man had embryonic stem cells injected into a disc in his lower back and it started growing teeth, lol. Embryonic cells are now rarely used because they have that chance (note there as a difference between embryonic, amniotic and umbilical cells). The only chance I can see of myself getting cancer of any type is if I start smoking two packs of cigarettes a day and drinking alcohol all day or something that actually causes cancer immediately after receiving therapy, which in turn could have an increased chance of affecting me because of the high number of stem cells in my body that are susceptible to turning into new cells. We don't want to turn these stem cells cancerous. My post-procedural instructions included in all caps: "DO NOT SMOKE. EVER." They also advised me against drinking and eating badly; they recommended a ketogenic diet with intermittent fasting, which also happens to be a suggested diet for Peyronie's by prominent members of this forum.

To rid oneself of CPPS/CP is a difficult process. It isn't a well-researched affliction at the moment, unfortunately. From what I've gathered through research, it has been defeated a couple of different ways. Here are 11 cases of hard flaccid recovery: https://www.pegym.com/forums/penile-anomalies-injuries/112678-11-hard-flaccid-full-recovery-cases.html which mostly consist of physical therapy/therawand, which involves a finger or a little tool going up your butt to release trigger points. Abstinence from all sexual activity seems to be the next most common theme for recovery, with our own member NeoV using it to successfully rid himself of the condition as well as others. Abstinence is key! You want to relax your pelvic floor muscles, NEVER clench them (kegel) and try to stretch your pelvic floor out and do reverse kegels. Traction also helps with hard flaccid, as do some different essential oil mixtures. Finally, there have been a couple of men who cured themselves with water fasting. The idea is that after water fasting for a time, all the muscles in the body release/relax and it also kills inflammation as well as inducing autophagy (good for Peyonie's). This is the best example I can give you: https://www.pegym.com/forums/penile-anomalies-injuries/54162-hard-flaccid-recovery.html As for a cause, well I got my case from intensely clenching my pelvic floor for hours at a time while having sex high on stimulants, lol. This caused my pelvic floor muscles to tighten up and my prostate to become slightly enlarged and inflamed (feels like I'm sitting on a golfball). This also caused my glans/corpus spongiosum to become partly deflated. Note that the urethra runs through prostate and the corpus spongiosum runs through the perineum (pelvic floor) so I believe these muscles tightening up cause said symptoms.

I haven't gotten around to applying the trigger point release or the diet, but abstinence shows a noticeable improvement for me, as do reverse kegels and not sitting for too long. I even got myself a "donut" cushion meant to relieve pressure on the pelvic floor/prostate while sitting. If you have to drive for long periods of time and you have seat warmers, that is soothing as well (as is any heat therapy applied to the area). Also, the leading community on hard flaccid (hardflaccid.org I believe) claims to have found the cause of hard flaccid (pelvic floor dysfunction) and is now closed under a paywall to access. If you sign up you receive a book that is essentially a collection of all their knowledge on curing it, which they claim to have found, called "Hard Flaccid: Unraveled." I thought about buying it but I'm assuming it's just a lot of what I already wrote in this post and I think it's ridiculous that they're charging people who are suffering for their wisdom on the topic, that's like us charging new members to join our forum and offering them a collection of knowledge ("do traction, ved etc.) upon payment. Not to mention their forum has been down for months, so you don't even get that benefit. But I digress. Hope that helped!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: suicidecomingsoon on August 27, 2018, 05:18:33 PM
Hard flaccid- pegym yeah pelvic pain syndrome
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on August 27, 2018, 05:24:14 PM
suicidecomingsoon, Hard flaccid is one of the main symptoms of CPPS, so my linking of those articles was appropriate given the limited amount of information on the topic; come back to me if you have something better, I've literally spent dozens of hours researching it. Another hallmark symptom of chronic pelvic pain syndrome/chronic prostatitis is pain after ejaculation. Also I'm speaking of nonbacterial prostatitis here, but it is all connected. The onset of my painful, tight pelvic floor coincided exactly with my hard flaccid and deflated glans/cs and things that improve one thing improve all others. My doctor backs me up on this. Most of what is available on the topic that comes from the internet comes in the form of "hard flaccid" and "soft glans" recovery threads. pey ron asked, I gave the best info I have to offer on the topic.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on August 31, 2018, 04:51:18 PM
Back on topic, I just spoke with US Stem Cell Clinic again. They can only administer 3 doses of concentrated cells at a time otherwise it is too much for your immune system, so I'm splitting one shot between both of my knees, one shot into the penis and another shot straight into my bloodstream. They charge $500 for the first shot and $250 for every one after that since it's a return visit, and another $500 per dose, so that comes out to $2750, plus air travel, hotel and food to get this done again in Florida. The penis alone would be $1000 and this includes PRP. I'm also considering getting the one-time $600 sample treatment of GAINSwave in New York the day before I fly out to Florida, because it helps the cells home in to the area treated with ultrasound. That is, if I don't just buy the damn ultrasound machine myself for ~$2000 (cheaper than the 6-session package).

I tried asking one of two doctors I know of in New York that do these procedures for pricing, and it was almost double so I might just take the mini-vacation and go back to the clinic. I'm aiming for late September/early October for the treatment. Also, I have a few specific spots on my penis that I'm going to have them target as injection sites for improvement. I'll update again when I have more info.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on August 31, 2018, 08:33:02 PM
Amazing!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: hope794 on September 01, 2018, 07:32:25 AM
Thank you for updating JS
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Gabriel on September 04, 2018, 01:25:20 PM
Hello boys,

Sorry for the late answer JS, but I read with huge interest what you posted. It has been crazy for me to realize that your story about CPPS is almost word by word what has happened and still happens to me.

1) About this, I won't make a long answer, but I wanted to mention that:
- The circle cushion did not work at all for me (it was a cheap Amazon one though);
- Practicing yoga significantly helped;
- Practicing abstinence, especially from masturbation, helped A LOT;
- Totally stopping coffee, tea, nicotin (even from vaping), reffined sugars helped A LOT (avoiding alcohol helps a great lot too, but I just can't stop from going out with my friends once a week);
- After sawing around 10-15 traditional doctors 5 years ago (urologists, phlebologists, gastro-enterologists, etc...), I saw 2 specialized therapists over the last 6 months: one who gave me exercises I was too lazy to apply, the other shove a finger up my butt for 15 minutes 2 times in 2 months... I can't tell so far how much it helped, but it does not seem to have done much more. Maybe I should go back to them though... Will see later, for the moment I already have my PRP/HA injections to focus on, and have a great bunch of work.

--> Anyway, even if I keep the symptoms at bay, I'm still not clear at all from this CPPS mess. I'll surely take some new measures in a few months, when I have more time and am (hopefully) out of the acute phase. And in this, your posts are really helping JS, so thanks a lot!

2) About your situation, I sincerely rejoince from seeing that you have such good perspectives. I was also considering investing in a gainswave machine, as for me it had done wonders on pain and EQ (but ephemeral wonders...); I may do it if my 2-4 last PRP/HA shots don't get me out of this bloody acute phase.

Anyway, thanks again for updating us, and all the best!!!


Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on September 04, 2018, 09:39:04 PM
I'm glad that the research I've done on CPPS has helped you, it's a hell of a condition. I feel like if I can clear those symptoms up the Peyronie's would be much easier to handle.

Regarding shockwave machines, the big question I have is: Will we be able to operate them properly/efficiently? I've never had the treatment but I planned on observing what they do. Do we know the setting to put it on, how long to go? I feel like I can do it, but I want to be sure before I buy one; I have to either do that or sign up for expensive treatment before my next round of stem cell injections.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Gabriel on September 05, 2018, 04:02:57 AM
That is indeed a big question JS; I have the same interrogation.

What I plan to do about it, is taking some day another appointment with my "first" uro who treated my with the lithotripsy, who is very nice and friendly, pay him for another session, and ask him about all the settings, techniques and precautions we have to know while doing this. I think and hope he'll answer frankly, as I was one of his most insoluble cases, and he seemed to be extra kind and comprehensive...

Of course, this is a long-term project; but anyway, I'm quite sure anyone can use a gainswave machine on its own (it's basically rubbing your junk with a spiky shower head), starting with the recommended power and applying it for no more than 2 minutes every week, then 3, then 5, etc...
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: curved on September 13, 2018, 02:04:09 PM
Just wanted to let the Board know that I underwent the SVT stem cell treatment today and will keep everyone posted on progress.  The recommended protocol for me was week 1 ESWT (4000 impulses); week 2 (today) ESWT (10,000 impulses) Harvest stem cells and inject into plaque and IV stem cells; week 3 (next Thursday) ESWT (10,000) impulses.  The doctor said that if it is a relatively newer plaque that still has some inflammation you can see results in 2-4 weeks.  If it is an older plaque it may take several months.  Additional thoughts were to take a nitric oxide supplement (I am taking NEO40) and VED at least 1x a day for 15 min, preferably 2x day for 15 min.  Will keep everyone posted and feel free to ask questions.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: quagmire333 on September 13, 2018, 07:55:39 PM
What treatment center is doing this? Good luck...I had no luck
with amniotic stem cell injections (Zahalsky method)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on September 14, 2018, 04:45:55 AM
curved, What was the protocol given regarding VED, and did your doctor explain why the VED was important for use with the stem cell procedure? Do you know the exact settings of the shockwave machine they use, and do you think you could operate one by yourself (I want to buy one and don't know how to use it)? Where are your plaques located, what kind are they and where/how many injections did you get? Where are you getting the procedure done and did they use PRP? Price/cost?

Also, I suggest a natural diet (ketogenic is great) with some sort of fasting if possible. Not only does it help Peyronie's by itself, but it also helps the stem cells do their work. Do not drink or smoke and abstain from masturbation/sex for the week immediately following injection. Good luck!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: curved on September 14, 2018, 09:23:39 AM
quagmire... my procedure was done by Innovations Medical out of Dallas.  They are part of the same program that Dr Elliot Lander created.  As far as i know Lander's facility and this one in Dallas are the only two that are doing SVT stem cells.  The key difference between amniotic and SVT is that SVT is harvested from your fat.  Supposedly it has a better "take" rate than amniotic.  Will keep you posted on any progress
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: curved on September 14, 2018, 09:41:26 AM
JS1991-- great questions and I will do my best to answer them.  In regards to VED the doctor gave me a fairly significant different protocol that was has been recommended by other on the Board here.  He recommended to start slow for the first few minutes but get to full engorgement (not so much that it is painful) and to leave it at full for 15 minutes.  He recommended this 2x per day if possible but certainly at least 1x.  He views this "penile therapy" as crucial to ongoing treatment.  The hope being that the stem cell treatment can reduce the curvature and the ongoing VED can help maintain any progress from the stem cell injections.

I do not know the exact settings but will try and find out.  I am highly confident I could operate it myself should I desire to get my own machine.  There are a lot of ESWT programs out there now... "Gainswave", "Big D", etc. I had tried ESWT as part of PRP injections I tried several months ago and had to stop because it was very painful when hitting my plaque.  The doctor explained to me that if you are using a new machine (less than 100-150 uses) the setting has to be adjusted down because the impact will feel much more powerful until the machine has been "broken in".  The ESWT I used as part of the stem cell protocol was much more tolerable.  Also it is important to consider what type of head on the machine is being used.  Doctor felt that the head that looks more like a small gun/pistol was more effective than the one that looks like a wand/steam cleaner (hope that makes sense).  I will try and get exact settings.

I have some significant plaque that is a bit of a horseshoe shape that is calcified on my right side (approximately 1 inch long) and then extends over the top (approximately half an inch but not calcified) and then a small amount on my left side.  The top part is what I am looking for improvement on as my curvature is upwards approximately 20-25 degrees.  I received 2 small injections of a numbing/blocking agent to help with pain of stem cell injections. I then received 5 injections of stem cells around the plaque(s). He then gave 4 more injections directly into the plaque (focused on the top) where he is also trying to break up the plaque.  My cost was $7300... which is pretty steep but if it works then obviously worth it.  They did not use PRP... I have had that in the past with no success.

I have been practicing 16/8 fasting for a few months but need to get a bit more disciplined on that.  Have also been back and forth with Keto for several months and currently focused on low carb but probably have too much protein to meet the definition of Keto.  Will try and get back to you with the settings.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on September 14, 2018, 05:41:08 PM
Excellent information, thank you for the thorough response. I knew VED could be used in conjunction with stem cells to improve their benefit but I couldn't find the articles that I read so I'm glad that you've shared that; I plan on using it for my next round of injections. As to the shockwave procedure, if you can find out the settings I'm planning on buying one and going off of what you say, so you would be saving me a lot of money and it would be much appreciated lol. The 16/8 fasting is great as is the low carb, keep that up it will help. I also believe water fasting for days or weeks can not only help reverse Peyronie's by itself but also greatly enhance stem cell treatment.

So you're using Cell Surgical Network? Interesting, did you opt to bank your cells? By the way, it is "SVF" not "SVT". This stands for stromal vascular fraction. It is a source of mesenchymal stem cells as well as various growth factors; the banking process consists of isolating and culture-expanding the stem cell portion of the SVF. I'm very happy someone else has decided to go through with the procedure, please keep us updated!

Also I forgot to ask: Are you in the acute phase or chronic phase?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: curved on September 17, 2018, 09:29:37 AM
JS-  I have requested the settings of ESWT and will pass along as soon as I get them.  I am in the chronic phase and have already tried Xiaflex (4 cycles of 2 shots each).  Thank you for the correction on SVF.  I did not bank any of the cells but the doctor indicated that if we needed to do another round the price would be significantly cheaper.  Will keep everyone posted.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Gabriel on September 17, 2018, 11:52:40 AM
Hey Curved,

Thank you very much for your long post, which I read with huge interest, and for your presence here!!

Keep us informed ; we wish you the best!!!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: curved on September 17, 2018, 11:55:36 AM
Thanks Gabriel... will do
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on September 17, 2018, 05:13:19 PM
Thanks curved! If you could also get the model of machine that they use, that would be great! Sorry if I'm being a pain in the ass lol.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: curved on September 18, 2018, 04:36:18 PM
JS- Unfortunately the doctor's office was not very helpful with settings (for some reason they view it as private/proprietary).  I do have one last treatment on Thursday and will see if I can get more information at that point. Here is a link https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643174/ to a study conducted on ESWT and peyronies.  I would say there is good evidence of pain relief and not as much evidence of curvature reduction.  The settings used in the study were 3000 shockwaves, .25mJ/mm squared at a frequency of 3Hz.  I cannot say if this is appropriate/ best setting or not.  I know my last 2 ESWT treatments were 4,000 and 10,000 shockwaves but don't know the settings. I want to be careful of the rules on products etc. but I know you can find several ESWT machines of various sizes/cost online (Dhgate.com).  I would imagine any company selling a machine would be helpful with appropriate settings. I hope to have better info on Thursday.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: curved on September 20, 2018, 10:50:36 AM
JS-  Here is what I found out today.  C15tip, 15hz, bar 4 pressure and 2,000 pulses per 1.5cm of penis length.  I do not know what bar 4 pressure means (assume it relates to a measurement on the specific machine they use which I could not get the name of but will continue to try).  I did learn that most high quality machines will come with different tips depending upon which body part is being treated.  Hope this helps a bit.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on September 21, 2018, 03:45:48 PM
curved, thank you for the thorough response, I'm going to try to apply the information you've given me when I go through ESWT.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on October 03, 2018, 03:48:26 AM
JS1991: how much fat do they need to liposuct for getting the necessary amount of stem cells? I am skinny and I am about to lose more weight, is that going to be a problem?

Also: $1000 seems cheap. Where should I go to get that treatment?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on October 09, 2018, 02:24:52 AM
pey ron, not much. You lose no more than a pound or two. And that's being generous. The $1000 price tag is a repeat visit using banked cells. Initial cost for me for Peyronie's was about $6,000. Banking cost an extra $3000, which gives me about 20-25 doses of culture expanded cells that I can get sent to me for $500 per dose. They can inject it for me for another $500, or I can do it myself for free, or I can try to find someone else to negotiate with to inject for me. I went to US Stem Cell Clinic in Florida.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Jack1909 on October 09, 2018, 06:02:15 AM
Guys the results of js should not be taken as an overall evaluation on the regenerative medicine. Honestly the fact you can freeze them and have them injected by yourself doesn't sound reliable to me...so far all the success stories and paper on the subject I read about have a totally different approach
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on October 09, 2018, 11:43:59 PM
I never mentioned anything about freezing cells. My fat was removed, my stem cells were collected and it was re-injected into me with PRP. That is what gave me my results. The banking process is simply them taking some of the cells they extracted from me and culture-expanding them in a lab over the course of a few months. The ice i mentioned is something on top of which they put the cells during shipping to keep them cool, if I so choose to have them shipped to me. Normally if one chose this they would have it shipped to a doctor, but I also reserve the right to have it shipped to my house and experiment with self-injection, which is dangerous and I do not suggest. That is where my figure of $1000 comes from. I could also fly back to Florida or find a local doctor to pay for injection, which is the suggested route.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on October 10, 2018, 12:56:13 AM
- Where do you store the stem cells? In your fridge? How long do they survive?

- How do you perform your own injections? How many at a time? In which points? At what angle?

- What gauge syringe needle do you use?

- How often do you do this?

- Did they perform any filtering on your stem cells to weed out the mutated ones?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on October 10, 2018, 02:28:27 AM
If I were to go through with this process, I would call the clinic and have them ship them to my house on ice via next day delivery. You do not store them, you must use them immediately upon receiving them. So even if you have them sent to a local doctor, they must be used immediately. As far as performing my own injections, I got the idea from Ben Greenfield (google him) who goes to the clinic I go to and now self injects every few months into the penis. He's kind of crazy though (there's nothing wrong with his penis, he's just trying to make it bigger lol). That combined with the fact that there is self penile injection training available for ED leads me to believe I can save money and do it myself. It would be a lot safer to do it with a doctor though. I do not know what gauge needle to use. I haven't self injected yet. In terms of filtering, I don't know but they are autologous, meaning my own, fwiw. I'm essentially just trying to do everything myself without proper certification because I believe I am smart and capable enough to and want to save money and time/convenience. I have the benefit of a compliant clinic that is willing to FaceTime me through the process.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on October 17, 2018, 05:34:39 PM
Here is an update guys, since it's been a while from me: Size seems to be stable since my gain of just under half an inch girth, I'll have to measure again to be sure. The one deep dent I had, which was literally as deep as the letter 'U'. Is now about half that. This was definitely my worst affected area; it had the roughest feel to it. Overall these gains were all in the top third/worst portion of my penis. Although I missed my target date of late September/early October for another round of injections, I am still planning to get them in November. I'm either going to get a local doctor to inject into the penis + do an IV myself, or I might just get 3 IV's (you can get 3 doses administered max, as a health precaution) in a row injected into myself. Both of these options would come literally the day or two before I start an extended water fast so I can mix the regeneration of stem cells with the waste removal of autophagy. If I go the triple IV route, I would use shockwaves to home the cells into my penis.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Gabriel on October 20, 2018, 04:17:49 AM
Hey JS,

Excellent post, fantastically interesting and hope-bringing, thank you!!!

As you know, I'll follow with as much interest your posts on your water fasting. I just wanted to warn you about a precaution I think you should take, from what I went through with my 3 days monodiet (which induces some of the benefits of a real fasting): on day 2 (but this can vary from person to person), I was feeling really, really bad, at a weakest, with a huge burst of all my inflammatory symptoms (prostate problems, pelvic pain, asthma, and of course my Peyronies Disease, with an almost permanent pain and metabolic panic in my penis).

I was then hugely surprised to see that all these symptoms disappeared on day 3, where I had NO penile pain/inflammation feeling AT ALL, and was full of energy. Maybe all this was just chance, but I read in many places that during a fast, some old conditions can rise again with a vengeance on days 1 to 3, when the body pours old "toxins" in circulation systems and "eliminates" them (no studies on this, so I'm being very cautious). Anyways this seems to be what happened with me, and trust me, on day two I would NOT have had ANY injection done in my miserable penis, nor would I have liked to have my swelled "nuclear pumpkin" post-injections penis... So maybe better you get injected a little sooner my friend!

Good luck to you!

Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on November 02, 2018, 05:16:08 PM
"Autophagy is required for human umbilical cord mesenchymal stem cells to improve spatial working memory in APP/PS1 transgenic mouse model": https://stemcellres.biomedcentral.com/articles/10.1186/s13287-017-0756-2

This study was for Alzheimer's treatment. My clinic HIGHLY recommended a keto diet and they encouraged me to fast (neither of which I did). I really believe autophagy and stem cells have great synergy.

Gabriel, from my research that burst of inflammation seems to be the body reactivating the healing process in any chronic issues we might have. And thanks for the advice, I'm considering avoiding injections and going with the IV + shockwaves.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: TonySa on November 02, 2018, 09:33:57 PM
A keto diet w IF is highly recommended for alz and dementias, one of the many potential benefits.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on November 29, 2018, 05:25:44 AM
Just wanted to update that after 5 months, the tissue in the top 1/3 to 1/4 of my penis no longer has a sandpapery feel to it, and is almost completely smooth aside from a few minor spots. This is by touch, it is still scarred, but definitely an improvement. I have been using VED on and off since August, so that might have contributed, but if I had to guess I would say it was the treatment I received.

Edit: Another update (11/30/18): Contacted all of my local clinics, the pricing is ridiculous ($750-$1000 per injection) so I've decided to go ahead with self-injection. Also going to have my friend who is a nurse give me an IV.

My next treatment will be within the next six weeks, I'll keep everyone updated.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on December 01, 2018, 05:01:13 PM
JS1991

I read some posts down but I din't find what you are injecting, how and how much it cost injecting yourself.
I will appreciate your answer

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on December 01, 2018, 05:57:24 PM
Hey james, I am injecting stem cells pulled from my own fat, which are currently being cultured in a lab (I paid to have them banked). I initially had the procedure done in June, it cost $6000 for the treatment and $3000 to have my cells banked. I went to the US Stem Cell Clinic in Florida, and I can now have them ship me my banked/culture-expanded stem cells to a local doctor for $500 per dose (plus cost of injection, which I stated in previous posts). Or, I can have them shipped to my house and do it myself if I want to save the money I would have paid for injections, which is what I will be doing. Definitely experimental and partially dangerous; I won't recommend anyone self-inject themselves without training because of risk of injury.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on December 01, 2018, 06:09:51 PM
I'll repeat what I told a few people who private messaged me. My take on stem cell is that they are effective, yet over-priced. There is a risk they will do nothing, there is also a chance you will have spectacular results, but most people fall in the middle (at least, according to the research I've done plus my own experience). I regained a little girth and got smoother tissue, but it was not a cure; you can get pretty much the same results with VED. I do have a theory that the mechanism of action in stem cells is different than the mechanism of VED in regaining girth, and so you could potentially stack the effects (which I will try), but unless I get cured I will continue to call it an effective, yet overpriced treatment. I do still have more injections to go and more time to heal, so my opinion will probably fluctuate (I am expecting to see more results in the future, so we'll see). Overall though, I am personally satisfied with my decision to go through with treatment, hence my next round of experiments with self-injection (which is way cheaper than going back and having them inject me).

If you have the extra cash, I would advise it. If you don't (one person that messaged me was a young college student with $0 prepared to take out a $10k loan) then I would go with all of the cheap/free treatments. As the price comes down I expect it to become a dominant field of medicine, especially as technology advances.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on December 03, 2018, 05:28:42 AM
Thanks for the replay JS1991 :)

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Gabriel on December 06, 2018, 02:55:37 PM
And thanks for your updates, it's always a great pleasure to follow you :-)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on December 20, 2018, 05:10:34 PM
I just read this article. Somehow scary:
https://edition.cnn.com/2018/12/20/health/infections-from-stem-cell-products/index.html

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on December 21, 2018, 09:45:16 PM
I have actually injected stem cells into patients. For joints. Not the penis.

With that said - I do believe penile stem cells to be effective.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on December 23, 2018, 07:28:05 PM
so, @JS1991: are you injecting them yourself, or using the help of a local doctor?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on December 26, 2018, 10:04:52 PM
pey ron, a few things. First, I have not had any luck finding a local doctor to inject me. Second, after hearing multiple accounts of injury from injections including someone who recently went to Landers' clinic, I am hesitant to self inject. Third, I would like to combine IV stem cells with Christipher1's at home shockwave therapy, but I'm currently convinced that fasting will heal me up for free.

So once I'm done with that experiment, I'm going to reassess, but until then I've cut all treatments including physical therapies and I'm also doing strict NoFap/No PMO.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Tony52 on December 27, 2018, 05:42:31 PM
JS1991,

What kind of fasting?

Tony52
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on December 28, 2018, 04:39:00 PM
Currently Water Fasting and eventually Dry Fasting on the Snake Diet. Check it out: Water fasting. - Peyronies Society Forums [Page 2] (https://www.peyroniesforum.net/index.php/topic,10493.50.html)

There's also some info in the ketogenic diet threads in the same subforum (Alternative Treatments). I'll have an update on my current water fast and I'm also going to start dry fasting around the New Year.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on December 28, 2018, 05:54:03 PM
Good luck with the fast.

My record is 4 days. (And stay away from coffee!)
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Whyisthishappening on March 07, 2019, 08:36:35 PM
Intratunical Injection of Human Adipose Tissue–Derived Stem Cells Restores Collagen III/I Ratio in a Rat Model of Chronic Peyronie's Disease
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377372/
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on March 16, 2019, 04:20:28 AM
why should we stay away from coffee? @christopher1
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: JS1991 on March 17, 2019, 06:03:13 AM
Some people insist on drinking coffee while fasting, which Chris and I completely disagree with; a fast is a fast, you don't drink coffee while your stomach is shut off. That's what he was referring to.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Gabriel on April 05, 2019, 02:55:16 PM
After my first three days snake juice fast, and despite a whole LOT of apparently solid information I had read about coffee being positive to autophagy etc., I agree with JS and Chris: I think that one should not consume coffee during his fast. Personnaly, each time after I had drunk coffee, I would feel strange gut activity and significant general gut discomfort for maybe an hour or more. Not to mention that my belly got swollen even more than normally during the fast, which I tend to attribute to coffee + stevia/erythritol consumption more than too much snake juice drinking.

Interestingly, tea and herbal decoctions did not seem to have the same negative impact; but I did'nt drink enough of them to be positive, so I'll try and let you know after my second fast in two weeks :-) !!
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on April 18, 2019, 10:50:07 PM
Dry fast is better than the water/coffee fast.

One only has to try it for 3 days to see the results.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on May 25, 2019, 11:43:41 PM
I am doing a 3 day fast for Memorial day. But I have to take my pentox, montelukast and supplements. Plus I won't wake up without at least 6 shots of espresso in the morning. Is it still better to limit water intake to the bare minimum for the supplements and coffee? It's far from a dry fast. But I am drinking way less than on a normal day.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: TonySa on May 26, 2019, 04:40:38 PM
Always drink plenty of fluids during a fast, otherwise you risk dehydration and all of its assocaited bad effects.  Caffeine should be fine but can lead to dehydration-so drink plenty of water also.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on May 28, 2019, 12:57:14 AM
Last two times I fasted I broke the fast after barely 1.5 days. Last two times I fast I was attempting a dry fast.

Every time I did a water fast, I didn't fail. I was able to carry it on for 4-5 days.

Dry fasts are hard :( Any tip on how to succeed?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on May 30, 2019, 07:26:15 PM
Just do what you can. I have seen gradual improvements with each fast when combined with NeoV's manual stretches.

I am currently back to water fasts, but it is Snake Juice. Also, I don't drink gallons of the stuff. Just enough for thirst.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: DELETED on June 01, 2019, 07:21:01 AM
Topic about stem cells where people discussing fasting. Ridiculous.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: popopo on June 01, 2019, 03:35:36 PM
I agree, we're getting off topic.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on June 02, 2019, 09:37:11 PM
True.

Anyway - a stem cell doc told me that the bone marrow stem cells work the best for the penis. It's all very new. I have heard it work well for ED. I don't know about Peyronies Disease whatsoever.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on June 05, 2019, 02:31:05 AM
I keep on stumbling on scientific papers where they say that fasting is good for stem cells. Google them up! This is not off-topic after all.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Curvature on June 05, 2019, 04:28:53 PM
I would like to start a new topic following my treatment how do i go about this? Because i will be updating results. Ive only posted on introduce yourself


Just like to put this out there i will be updating my results, not sure how to use this forum, but my updates will be under introduce yourself as i cant update on every single thread if that makes sense

Hi i have had peyronies for 8 months now. Less than 30degree curvature
Last month i had a stem cell adipose msc injection into the curve.
Along side with
Biolight therapy 30min
Electric shockwave therapy 40min
Unltrasound therapy 20min
Traction, 30min
Iv therapy- meyers cocktail
Metatherapy, 30 mins
Life system, 2 hours
And prp injection
I had this therapy done for a course of 4 weeks, 2 days each week, same therapy each week
Stem cell injection only once.

Advised by the urologist to do traction every day 30mins in morning
30mins in evening,

Will update results


Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on June 06, 2019, 01:22:23 PM
Looking forward to reading about your results.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: DELETED on June 08, 2019, 04:11:54 PM
Quote from: Christopher1 on June 02, 2019, 09:37:11 PM
Anyway - a stem cell doc told me that the bone marrow stem cells work the best for the penis. It's all very new.


Did he provide you any article about successful treatment with stem cells for Peyronie's Disease or Erectile Dysfunction or other penile condition/disorder?
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: pey ron on July 04, 2019, 02:58:17 PM
can someone please summarize which clinics offer stem cell injections???
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Whyisthishappening on July 05, 2019, 09:12:39 AM
https://www.ncbi.nlm.nih.gov/pubmed/30988428 

Intratunical injection of autologous adipose stromal vascular fraction reduces collagen III expression in a rat model of chronic penile fibrosis.
" Peyronies Disease animals developed subtunical areas of fibrosis and elastosis with upregulation of collagen III protein. These fibrotic changes were reversed after injection of SVF. We provide evidence that local injection of SVF reverses TA fibrosis in a rat model of chronic phase of Peyronies Disease"
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: james1947 on July 20, 2019, 05:46:31 AM
Additional readings in the subject for more deep understanding:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472998/
https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/stromal-vascular-fraction
https://www.frontiersin.org/articles/10.3389/fcell.2019.00088/full
https://www.cellr4.org/article/2533

James
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: drew67 on August 03, 2019, 11:49:05 AM
Wonder if anyone here had stromal vascular fraction injections
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Godisreal on December 23, 2019, 03:18:05 PM
Could someone with knowledge please update the forum on stem cells? Are there anything new? I read about great success with animals and so on, and that gives me a feeling that something potent is on its way. Am I wrong to believe this? It would be great if someone chimed in.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: popopo on December 23, 2019, 04:46:06 PM
Dr Atala was able to regrow penile tissue back in 2014, but none of it ever gets approved by the FDA and we never get any updates whatsoever. The science is there, it will just not be avalaible for at least another 10/20 years so bye bye youth.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Godisreal on December 23, 2019, 06:24:32 PM
There's only one thing to do. Get rich and pay the scientific research singlehandedly, ultimately getting world recognition and leading the world into treating the disease with stem cells & tissue engineering. Imagine financing the money that's needed to promote stem cell research and advancement and become the face of Peyronie's treatment. You'll get known as "The Man who cured the incurable disease". This way, the scientific research is boosted and perhaps the final cure  will be available much sooner than expected. Or you could keep being depressed and doing nothing. It's your life.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: popopo on December 23, 2019, 06:42:27 PM
Setting unrealistic and almost heroic like goals for yourself won't make you feel better. It will only make you realize even harder that there is no point. You don't really think any of what you just said will happen, right? If you do, please tell me the secret to getting rich and doing impossible stuff cause if that was a valid option I'm sure everybody would just do that by now. Also, I wouldn't want to be the face of peyronies. I try my hardest to keep this all a secret and wouldn't want to be known as the guy that cured his deformed penis I would actuall6 deep down just wanna be a normal male that never had all these beta male issues to begin with.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Godisreal on December 23, 2019, 07:10:08 PM
Well, you can't "be a normal male who never had these problems to begin with". When are you gonna accept the fact and move in the right direction? You're clearly dwelling on the same sh*t over and over again. The way you put and select your every word are to me very toxic and I understand you feel so bad. Wow man. There's no "secret to getting rich" lol, it's called hard work & dedication. If you really want change, don't sit on your ass and complain constantly - I know this is a great place for venting and so on and I appreciate that and i do it myself.
But at a certain point you have to move forward and not constantly seeing things from that promiscuous & pessimistic perspective. I can't speak for you specifically, but there's no such thing as "beta problem". It's how you handle the problems that ultimately makes you an alpha or a beta. This however, is not written in stone.
It's to me insane how you after so many years still dwell so much on the past and how you regret doing things. You can't change them man, no matter how pathetic or devastating the mistakes are - there's no changing them. Okay, you have erectile disfunction and a crippled dick. What exactly are you wanting so much? Wild sex? A bigger dick? If you got your dick back you probably would've made up fake problems in your f*cked up head and you start dwelling again & again & again. Then you f*ck up again because you're obsessed. Same goes with everyone. There's no point in getting cured if you haven't treated and fixed up your mental health & control.
I strongly believe that your useless attitude towards life is the thing that kills your chances for beautiful relationships with beautiful women, healthy dick or nah.
You can have ALL these things that I bet you want. But you have to commit.
I only want the best for you, I'm just truthful even tho I might be harsh right now.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: popopo on December 23, 2019, 07:27:11 PM
You're wrong bro. I am like this because I can't fix my dick and nothing ever will. Once you start to realize that yourself and when you have been here for longer than the couple of weeks you are here you too will understand that you either ACCEPT no sexlife or end your life. I told myself I could fix this too, but it's getting a bit old cause it's a lie to keep me going. So I ask you this: "can you accept being dickless for life?" If the answer is yes than good for you and then yes, your life is worth it and you'll find a way. But you still believe you can fix this so it's clear to me you CAN'T accept having no sexlife.If you CAN'T accept that however, be prepaired to be dissapointed for life. My point is that you can change attitudes.. I did too for a long time! Be positive yey! But it wont fix your dick trust me. And what about you then, huh? You've only been here for a couple of months and you only stay so happy cause you really believe your dick will be fixed, but it's not in your own hands. You will need a doctor to fix you, right? Or are you really gonna get rich and spend a couple.million dollar so atala will operate you without FDA approval? Be realistic man that aint gonna happen. You literally said you think keto, fasting and diet isn't necessary and you don't "like that". Well let me t3ll you this.. if you can't even be disciplined enough to stick to a F^@$!ng diet how are you going to "work hard" and get rich?? I'm not trying to flame you, just pointing out how hypocritical you are right now.

My dick can't be fixed and that's my problem. Don't try to make this more difficult than it is, cause that's all there is to it. And NO I don't want beutifull relationsships with beautiful girls I CAN PHYSICALLY NOT F~@<. I want thr same as you that is my dick back to full health and it's not happening. Don't be a fool and tell me if I was happy it WOULD be possible cause that's not true. If a postive mindset is all it took I would have a healrht dick by now.

In short: the problem is NOT that I THINK there is no cure. The actual problem is THERE IS NO CURE!

You can hate me now if you want and I don't blame you. Just realize that no matter what your mindset is, as long as there are no proper treatments you can't fix this just by being "positive".
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: popopo on December 23, 2019, 08:10:38 PM
And yes, I am in a very bad mood right now and may sound unreasonable, but even on a good day where I try my best to make things happen this still haunts me and the fact I can do ANYTHING I WANT except get my dick back makes me not wanna do anything. Call me mentally f'~c<+d I don't care.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: samsung on December 23, 2019, 08:42:51 PM
There has to be another way. You're both wrong, but I don't know what's right.

It has to be a matter of degree. I wear glasses. I guess that gives me "fake" eyes. Just like an implant would give me a "fake" dick. I know I am required by man law to kill myself. I think about it every day. All day. However, I have had these fake eyes for so many years I do not spend much time thinking about that. I know a dick has much more meaning attached to it, but the principle somehow has to be similar. This has destroyed me and it has destroyed many of us, but there has to be a way through. I just don't know what that is yet.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: popopo on December 23, 2019, 09:11:10 PM
Well, I do know what the solution is. It's getting cured. I also wouldn't really mind if the dick I got was "fake" because it's an implant. But what bothers me a lot about tje implant is that it still wouldn't adress the underlying inflammation issue and that I can never get a size that wouldn't be considered "small" even if I did get an implant. I wanna get my size back. I was never really happy about my size anyway, so having to pay a lot of money and still be left with a lot less size and a tube inside my dick just sounds too anticlimatic for me to go for that. I know I can be a jerk sometimes and I complain a lot, but what bothers me is the same old same old "VED, pentox, traction" discussion like it's the new best thing while in reality these are torture devices that many doctors don't even agree on if it's effective. What I hate is that everybody EXCEPT others who have this as well (and even some of those people) act like this isnt a big deal and there are plenty of treatments, while there aren't. If we keep thinking as a community that the treatment options are plenty and we don't really need new treatments we just need patience using the treatments from 50 years ago then nothing will change. I wish everybody was as angry as me so they would HARRAS doctors for new treatments and bitch about it till change would actually happen. I know I'm a whiney bitch in the eyes of some of you, but at least I don't smile and nod when speaking with urologists. I tell them the truth about them not being able to help so maybe they one day realize they have to come up with options for guys like us. I wish everybody here would get psycho like me so that society can no longer ignore us. I don't even know if my anger will lead to anything, but at least I won't lie to myself and others with this disease that it's not so bad and you just have to use more VED or traction the very same things thar actually injured me in the first place and made me worse a couple times after that even when being very gentle. Anyway, as you can tell I'm desperate right now and I really feel like some of you are not as desperate as you should be and I seriously hope more guys get this crap and realize how f'~c<+d they are and come knocking at the door of urologist and tell them "HELLOO we are people too and need proper treatment instead of you cutting half of my penis with a nesbit and tell me I'm healthy now".

Rant over.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Godisreal on December 24, 2019, 04:55:51 AM
I doubt anyone here either hates you or think you're a b*tch. We just feel sorry for you.
There are a number of treatments that is proven to work & have radical success.
You're down so low mentally that you keep trying to bring people down with you in the grave. If you wanna stop fighting and calling me a hypocrite, that's on you. But the actual accuracy in your statements are completely broken & desperate. It's clear you have given up hope.
The reason I won't start a diet is because it's often considered optional if you're already using powerful supplements and drugs.
And if the thing i have to do is to spit up millions of dollars to get my dick back to nursing health with new & extraordinary techniques that's not approved by the FDA, then that's exactly what I'm gonna do. Because I have a mindset that few others possess. The law is to me just a writing in a book. Good to a certain extent, but not too good & relevant in a lot of things. I know for sure that an insanely talented Peyronie's specialist would take my black money without hesitation and treat me. Nobody have done just that, and if I have to be the first one, I'll be happy to. This is very likely not even needed in my case, I'll probably be good after months of oral treatment.
But since I still can have sex and achieve good orgasms, I'm all right. It's just limited position-wise. Lastly, you're saying that you're trying your hardest to cover this up and to stay low profile, yet you're saying that everybody else should do like you and freak out & become psycho and start knocking on the doors of people to tell them "PAY ATTENTION TO ME IM IN DEEP PAIN". Acting like a helpless b*tch sure won't cure anything, illegally or legally. In this way you would expose yourself to the public constantly - just like you said you didn't want to. Hypocritical in its finest form. 
If I were you, I would consult to a therapist because you have deep issues to control your emotions as well as your problems.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: popopo on December 24, 2019, 09:32:08 AM
You say you got a mindset that few others posses, but I honestly doubt that. I also rant here so I don't rant to for example my friends, but yeah, when I'm at the urologist I tell him the truth and don't act like they help me when they don't. The "potent drug" you are on is pentox, right? Well it's not as potent as you think cause I've been on it for years now and it only gotten worse. But you can believe all you want that with the right mindset and trying things I have tried for years will help you and if so good for you, but I'm telling you it's not that simple.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Lostandsad on August 12, 2021, 06:15:15 PM
There hasn't been much talk in this thread for a while. Anyone care to update on their experiences or have some news about new stem cell research or studies? It's pretty hard to find anything about stem cell technology and peyronie's on google.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Dent4ever on January 24, 2023, 01:37:21 AM
I went to South America for Embryonic Mysenchemal Stem Cell P-shot plus another 150M stem cells intravenously. Energy wise, felt great, solved my joint problems too, but as for my peyronies it didn't do anything.
Title: Re: Stem Cells & Adult stem cell injections for Peyronie's
Post by: Christopher1 on June 02, 2023, 05:08:02 PM
Thank you for posting about your stem cell experience.