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Peyronies Disease TREATMENT Discussion Boards => Alternative Treatments of Peyronie's Disease => Topic started by: melting on October 21, 2019, 06:54:42 PM

Title: DMSO+X Revisited 2019
Post by: melting on October 21, 2019, 06:54:42 PM
This was by far the best treatment for my peyronies plaques. 
The infamous thackers Formula(DMSO+Castor Oil+ACV 70/20/10 mix) and then various DMSO+X mixes. (+ traction + pumping + healthy eating)
Anyone who wants to catch up there's a lot about DMSO and Thackers Formula on this forum(mostly old) like this thread: https://www.peyroniesforum.net/index.php/topic,39.450.html (please don't ask me basic questions before you read this thread)

It turned me from painful erection and profound hourglass to fully functional.
I could feel the tissue softening whenever I applied it for some continuous days or at best weeks.

I still have some nodules inside after I stopped the applications. Some weeks ago a little sex accident and it made me revisit with motivation to get rid of the last faulty tissue.

What me, and I guess many people stopped applying, was the cumbersome application.
The application is important cause optimally you'd use such solution daily! (cause whenever I stopped the plaques hardened again)
The biggest problem with the DMSO+X(like Ascorbic Acid, magnesium or Vit e) was that it's runny.
With Thackers Formula the biggest problem was that it didn't mix.

THE SOLUTION? Emulsifiers

Perplexed got a mix from his doc that was easy to apply: https://www.peyroniesforum.net/index.php/topic,6096.msg65747.html#msg65747 
He didn't know and name the other ingredients which held the solution together(and his doc is retired now). Most probably some sort of emulsifier and preservatives. 

I got all the stuff DMSO, Castor oil(cold pressed), vit c, magnesium etc. and now will work on finding a way to get an easy usable solution/creme/wax/lotion to apply the good ingredients without hassle.


If we manage to combine DMSO with Castor oil and the water soluble stuff like ACV, Ascorbic Acid, Magnesium, PABA etc. into one solution, that would be amazing!
We sure need to avoid any stuff that we don't want to be shuttled into the body by DMSO.

I would love if anyone has an idea on what emulsifiers and ingredients to use that go along with DMSO and the other helpful supplements. I found this great resource: https://www.soapqueen.com/bath-and-body-tutorials/lotion/how-to-create-homemade-lotion-recipes/  (I hope link is ok)
Title: Re: DMSO+X Revisited 2019
Post by: melting on October 21, 2019, 07:31:32 PM
These are some:



Popular Lotion Emulsifiers

Polawax Emulsifing Wax: This waxy material is usually used between 3-6% of the total weight of your recipe. Manufactured by Croda (Polawax), this wax comes in the form of white pastilles. This product is a proprietary blend of ingredients.
   
Emulsifying Wax: Emulsifying wax is a generic version of the popular Polawax Emulsifying Wax. It is made of Cetylstearyl Alcohol and Polysorbate 60. This wax comes in a mixture of pastilles and irregular waxy flakes. This is a great choice if you like your product to have a nice "slip."

Bio-Mulsion Wax: This wax derived from olive oil is a great natural alternative for Polawax. Normal usage rates are between 2-8% of the total weight of your recipe. This emulsifier comes in the form of medium off-white flakes.

BTMS-50: This emulsifier is vegetable based, and is recommended to be used at 1-15% of the total weight of your recipe. BTMS-50 contains a large percentage of conditioning agents (Behentrimonium Methosulfate), which makes it a good choice for hair care in addition to skincare.  It comes in the form of white pastilles. BTMS-50 is also capable of emulsifying silicone. BTMS-50 tends to add a less greasy feel to lotions than other emulsifiers.

Note: Polysorbate 80 and polysorbate 20 are popular emulsifiers as well, but we do not recommend using them as the primary emulsifiers in your lotion recipes. Instead, polysorbates are commonly used as fragrance and essential oil solubilizers.

Lecithin in Emulsions
Lecithin makes a good emulsifier because the hydrophobic end dissolves in oil droplets and the hydrophilic end dissolves in water. ... Oil droplets in water are protected in the same way by lecithin so the emulsion stays stable for a long time.



Lecithin seems like a good choice for the thackers formula. Sounds like it could bind to the watery acv+x and the castor oil.

I will try to find the best one and then mix it. I hope some of you will help a bit with the thinking and getting there.
Title: Re: DMSO+X Revisited 2019
Post by: melting on October 21, 2019, 11:00:37 PM
TO THICKEN THE SOLUTION

Would be great to have it more gel like.
Xanthan is natural and no bad indications and often used.
I saw in some cosmetic forums that thickener should first be mixed with oils.

So in the case of "thackers formula".
First Mix DMSO with ACV(I also like to add ascorbic acid powder)70/20 which gives a heat reaction.
Then mix the castor oil with Xanthan.

Now I combine it all and then add the emulsifier(lecithin) at last OR add the emulsifier to the DMSO/ACV and then add the oil/Xanthan..
I guess I'll have to test that and which works better. Obviously anyone testing along, please keep common sense, I test everything in small quantities on my hand first for skin reactions.



Title: Re: DMSO+X Revisited 2019
Post by: pap on October 23, 2019, 03:29:35 AM
Quote from: melting on October 21, 2019, 06:54:42 PMI could feel the tissue softening whenever I applied it for some continuous days or at best weeks.

I experienced the same! Used DSMO + Magnesium chloride + Castor oil afterwards twice a week.
Title: Re: DMSO+X Revisited 2019
Post by: melting on October 23, 2019, 11:31:14 AM
pap, and did some sort of plaque/scar tissue still stay?

My guess is that it takes a lot of constant daily, possibly several times a day, applications to get rid of all the faulty tissue. The tissue basically has to be bathed in it.

I also noticed that skipping some days led to the plaque hardening again.
Title: Re: DMSO+X Revisited 2019
Post by: melting on October 23, 2019, 11:52:43 AM
Alright, I experimented a bit..

I didn't want to bring the DMSO with my mixer into contact to avoid plastics leaking into the solution.
So what I did:

Mixing Castor oil with some Xanthan and Lecithin. Dissolved quiet nicely.
Then added the ACV and mixed it. Created a foamy substance.
Then seperately I mixed DMSO with some ACV to create the DMSO heat reaction to avoid it happening later. 
Then I put it all together into a brown glass and shaked it.

The result is a good mix that doesn't separate like other DMSO+oil solutions.(like Thackers formula)
Applying to the skin and penis, no adverse reaction. After 30 minutes not much remains on the skin.(probably the high molecular weight parts like xanthan and lecithin)

The exact amount of emulsifier is now the question.. Need to find a middle ground where it's not runny but also not sticky with too much remains on the skin.

I deem this endevour as a success for now. I wish I had professional chemist means and knowledge ;)

Title: Re: DMSO+X Revisited 2019
Post by: pap on October 24, 2019, 02:51:30 AM
Quote from: melting on October 23, 2019, 11:31:14 AM
pap, and did some sort of plaque/scar tissue still stay?

My guess is that it takes a lot of constant daily, possibly several times a day, applications to get rid of all the faulty tissue. The tissue basically has to be bathed in it.

I also noticed that skipping some days led to the plaque hardening again.

No, the scar tissue stayed. But I stopped the therapy when I had no more problems (pain, soft glans, bending).

I guess there is a difference between the scar tissue and the plaque. The doc said the plaque (calcification) went away (after 1 year).
The scar tissue is still there.

But I wasn't using the DMSO so frequently (1-2 times a week). I was afraid that it could have side effects.

If I use it more often (daily?), the scar tissue will go away and not come back?
Title: Re: DMSO+X Revisited 2019
Post by: JS1991 on October 24, 2019, 04:09:13 AM
I believe the user Gabriel has seen similar results. Thanks for posting.
Title: Re: DMSO+X Revisited 2019
Post by: Whyisthishappening on October 24, 2019, 06:13:30 AM
what do you believe about this
INFLAFORTE CUT.SOL 1,5% W/W BOTTLEx30 ML
Dimethyl sulfoxide
Glycerol solution (85%)
Ethanol
Propylene glycol
Water purified
its the only thing with dmso i can find in my country
Title: Re: DMSO+X Revisited 2019
Post by: melting on October 24, 2019, 02:09:40 PM
Whyisthishappening, sounds OK, you can try on your own responsibility. Always try a little bit on hand or leg skin before.
I'm sure you can ship pure DMSO from some other EU country to .gr ..
(Guys please be careful about DMSO and inform yourself, its all out there detailed and talked about)

pap,
-If I use it more often (daily?), the scar tissue will go away and not come back?
I don't know, I assume so. Could take many weeks/months of daily, at best 2-3 times daily, application.
I'm sure if you would put the plaque/scar into the solution isolated out of the body it would dissolve.
With DMSO transdermally some of it will reach the scar but not everything. Surely more than any oral medication could.
Always apply logic and common sense and be careful with anything you do transdermally. Could be every other day is good too..

I'm trying to get rid of the rest of my plaque now applying 3 times daily at least. I applied my new solution the last 2 days about 30 times, skin feels ok. No adverse reactions. Probably going for a 2nd solution to mix it up a bit from day to day.
Will keep posting.
Title: Re: DMSO+X Revisited 2019
Post by: Whyisthishappening on October 25, 2019, 05:53:16 AM
melting do i need to mix something else to be effective also its got diclofenac (inflaforte)
Title: Re: DMSO+X Revisited 2019
Post by: melting on October 25, 2019, 06:51:18 PM
Whyisthishappening, try it. Sounds like something vs. inflammation which could be useful in the active phase.

I only know definite about what I tried, which I documented. I can only speculate on what I didn't try myself.
You can add alc ,vitamin e and olive oil for example. But maybe not enough DMSO in your product..  I don't know! 

My mixes are all documented in this forum (https://www.peyroniesforum.net/index.php?action=profile;area=showposts;u=11063). Constant application is the key, daily or whatever works for you. This is not easy, I know.
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on October 26, 2019, 12:02:34 AM
Only study I recall that supported a topical agent was the voltaren (no DSMO needed).
Title: Re: DMSO+X Revisited 2019
Post by: melting on October 26, 2019, 10:56:00 PM
Apply simple logic. If you put a topical creme without a good transdermal agent on your skin then it will just stay in the upper layers of your skin.
Ascorbic acid and magnesium have such a low molecular weight that they can be uptaken by the skin but it's very inefficient without a transdermal agent.
You wan't the supplemts to go right to the plaque and not float around in the blood never getting there.

No need to wait for a study that will never be done if there isn't a profit to be had anyway. 


Title: Re: DMSO+X Revisited 2019
Post by: melting on October 27, 2019, 07:11:35 PM
Alright, 7 days in, daily as many applications as possible(at least 3) and the tissue feels great. Plaques very soft to palpation.
It really feels like the way I applied it the tissue was bathed in the solution.   

No adverse effects, but a place on my hand I tested a solution without oil is dry as hell no matter what I do. Affected the skin. So always add some good oil(castor, olive, calendula) to the mix or moisturize after.
Title: Re: DMSO+X Revisited 2019
Post by: melting on October 27, 2019, 07:19:36 PM
I will create several solutions now to make sure I attack the plaque from all angles.
What always worries me is that some supplements might have interactions with others making them not effective
So circling them makes sense.


PABA
:
Quote"Decreases fibrosis and inhibits collagen formation by decreasing serotonin levels, increasing monoamine oxidase activity and inhibiting fibroblast glycosaminoglycan secretion"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893507/
QuotePotassium para-aminobenzoate (Potaba) is an antifibrotic agent that is thought to increase tissue levels of monoamine oxidase, decreasing the level of serotonin that contributes to scar formation in Peyronies Disease. In a 1-year placebo-controlled trial, involving 103 men with known Peyronies Disease, select patients were given 3 g of Potaba four times a day. Seventy-four percent of those in the treatment group (compared to 50% in the placebo group) responded with a reduction in the plaque size or a decreased penile curvature of up to 30%.4,29 Potaba is an expensive medication, with a large and frequent dosing regimen, leading to significant patient expense. Potaba was not commented on or assessed in the recent AUA 2015 guidelines.25
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857830/
POTABA basically = PABA

Molecular weight: 137.14 g/mol (good for transdermal)
Quote
The solubility of PABA is 6.1 g/l at 30oC in water, 125 g/l alcohol and 17 g/l ether. PABA is soluble in ethyl acetate and glacial acetic acid, slightly soluble in benzene, and practically insoluble in petroleum ether. DMSO 27 g/L
(compare to ascorbic acid: Solubility in water, g/1l: 333g)

These are oral treatment studies. Obviously with PABA half life(low) it's a big chance it never reaches the plaque if taken orally. With trans-dermal we can "bath" the tissue in it pointedly where we need it.

Title: Re: DMSO+X Revisited 2019
Post by: TonySa on October 28, 2019, 10:18:24 PM
I agree there won't be any US studies due to the profit motive.  However, it's been around quite awhile and the only reported real success was w Thacker years ago and nothing since then.  If you're going to try it, please take objective measurements and let us know what changes you specifically see over what time period and the protocol you used.  Thxs
Title: Re: DMSO+X Revisited 2019
Post by: melting on October 29, 2019, 12:57:06 AM
It's been around, yes, but I doubt that many tried it and as long as people badmouth and slander it, fearmongering, without any logic, no matter if good or bad intention, insecure sufferers won't. We saw that with thackers formula already. Same old.
Instead they eat thousands of dollars of supplements that will never reach their plaque but end up in the toilette instead, literally :) But somehow no one asks these merchants for "objective measurements"..? hm..

DMSO is a well researched and tested substance, let's be clear! Used for all kinds of ailments by many people for decades without anyone being able to make a(big)profit of it. Just some DMSO, Water and Ascorbic Acid(Vit C) will soften your plaque for $3,50.

Yes, if you mix DMSO with poisonous chemicals and put it on your skin it can end badly, yes, if you don't breath you will fall unconscious...
Title: Re: DMSO+X Revisited 2019
Post by: pap on October 29, 2019, 04:22:46 AM
Quote from: melting on October 29, 2019, 12:57:06 AM
Just some DMSO, Water and Ascorbic Acid(Vit C) will soften your plaque for $3,50.

I do agree to this observation, the scar tissue will soften noticeably and stay like this for some days.
Instead of Ascorbic Acid I mixed DMSO with Magnesium chloride (spray used as muscle relaxant in Germany).

My Peyronies appeared after a trauma just under the glans, resulting in a ~5 month acute phase and a ~30 degree bend.
Doc gave Potaba -> does nothing. Then Tadalafil, which helped to restore the blood flow.

In addition I started by myself with the DMSO treatment, twice a week. Can't tell if DMSO or my body healed it by itself, but for sure DSMO softens everything, which results also in less pain during erections.
Title: Re: DMSO+X Revisited 2019
Post by: melting on October 29, 2019, 03:51:54 PM
Sorry Tony for being a bit aggressive in my reply. I just felt it was a bit unfair with you replying on every post I made that DMSO has no evidence etc. holding it to a different standard than everything else. No hard feelings though.
Maybe we need an extra thread discussion about DMSO? I would like to keep this thread focused on DMSO + X with details. Warning about alternative treatments are on top of the forum..

Pap, yes, Magnesium is a good idea too and the "magnesium oil" formula is great to mix with DMSO.
I left it out for now cause if you mix magnesium with ascorbic acid it changes to "magnesium ascorbate". Maybe still a good transdermal supplement..?   

I tend to use magnesium in another solution. Changing it up with solutions that work in different ways on different days appeals to me, to minimize them canceling each other out, before doing their work on the plaque.

I think its wuse, before adding several supps in one, to check for the interactions.

POTABA and PABA(almost the same), orally will not hurt but it's most probably a waste as it has a short half life. Another user took it with high frequency several times a day to counter that. I still think transdermally we will get much more to the plaque site.

Title: Re: DMSO+X Revisited 2019
Post by: TonySa on October 31, 2019, 09:18:22 PM
Hi M, I like your idea of a specific DMSO thread.  Actually, I used it myself for several months with no change in curvature.  I began to have some w traction/VED/pentox and low dose PDE5i.  Ultimately not enough, and since had severe Erectile Dysfunction went w the implant.  For all treatment one should take objective measurements...without it we'll never know how effective it was for someone.  Good luck and please keep us posted on how it goes.
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 04, 2019, 10:18:19 AM
I ordered:
Natriumthiosulfat Na2S2O3 pharmaceutic quality.
molecular weight: 158.11 g/mol (good!)
Solubility in water 70.1 g/100 mL

QuoteThe beneficial effects of sodium thiosulfate (STS) are thought to be due in part to its ability to enhance the solubility of calcium deposits. STS has a serum half-life of 15 min. STS facilitates the mobilization of calcium from vessels affected by calcium deposits.
QuoteFurthermore, the enhanced aqueous solubility of calcium thiosulfate allows for successful mobilization and clearance of the vascular and soft tissue calcium deposits (5)
Very interesting for our Plaques:
QuoteAnimal data, using normal and anuric mongrel dogs, demonstrated that STS distributes rapidly throughout the extracellular space
extracellular space = (also) connective tissue(like the Tunica)

Natriumthiosulfat is basically a chelating agent that "connects" with calcium which is said to be a big part of the plaques and fibrous tissue("calci"fication).
Natriumthiosulfat is a great candidate for transdermal application as in studies they had problems with it on the stomach.
We also see again how such a supplement could fail a lot of studies were they might only use it once a day orally. With a half life of 15 minutes chances are high none of it reaches the penis and the site of the plaque if used orally.

Note: I'm going mostly for dissolving/melting/destroying established plaques. This thread is not about putting down inflammation and stopping the onset of a plaque(for which other substances might make more sense!)

(always do your own research and apply logic and common sense!)
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 04, 2019, 10:37:41 AM
I'm happy for anyone throwing out some other ideas for substances that could work transdermaly.
What I'm still trying to figure out is in what succession to use these substances. 

All in 1 seems not so good. For example pre-mixing Sodium Thiosulfate with magnesium could change it to magnesium thiosulfate which might loose it's ability to chelate Calcium.

I think I'm going for 1 mix, the ACV + Castor Oil + some Ascorbic acid combo and then use several DMSO+X solutions and cycle them from day to day. I think adding some Castor Oil or similar to every solution won't hurt. It's always great for the skin. 

DMSO + Ascorbic Acid same day as Vitamin E is interesting as Ascorbic acid interacts with Vitamin E replenishing it after VitE takes up free radicals. I'm also thinking.. If something like Magnesium or Thiosulfate chelates Calcium(calcified plaque) then I could imagine free radical being a byproduct which might be wise to be picked up by VitE and other supps connecting to free radicals..
Title: Re: DMSO+X Revisited 2019
Post by: Whyisthishappening on November 04, 2019, 10:47:16 AM
"This thread is not about putting down inflammation and stopping the onset of a plaque(for which other substances might make more sense!)"
which substances do you believe could be helpful (inflaforte might do that job?)
thank you melting
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 04, 2019, 10:52:55 AM
Vitamin K2-MK7
Molecular Weight 444.648 g/mol (ok..)
FAT SOLUABLE (so combine with Castor oil?!)

QuoteVitamin K2 MK-7, taken in adequate nutritional doses, has been shown to reduce the progression of vascular smooth muscle (arterial) calcification and even reverse existing levels of arterial calcification.

This is very interesting cause Smooth Muscle is part of the Penis and I know that one of my plaques sits on the inner side of the tunica but seemingly connected to the Smooth Muscle(creating hourglass indentation)

Quote
Vitamin K2 specifically addresses calcium deposits in soft tissue. This has been used to reduce calcification in the aorta. The result is much lower heart attack rates. Rats and mice that have no Vitamin K2 typically die within months from aorta calcification.

QuoteVitamin K2 MK-7 is a fat-soluble vitamin. Like all fat-soluble vitamins, it can degrade in certain environments and formulations. K2 is particularly susceptible to degradation in formulation with calcium or magnesium
BINGO! What I said in the prior post. Have to be aware of the interactions. So K2 alone with some "fat"(castor oil has fatty acids)
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 04, 2019, 11:06:09 AM
Quote from: Whyisthishappening on November 04, 2019, 10:47:16 AM
which substances do you believe could be helpful (inflaforte might do that job?)
inflaforte, yes, as the name indicates ;)

Thinking about it anti-inflammatory substances will still help with hardened plaques cause "attacking" the plaque might still create inflammation that should be dealt with. Just lower focus on it., In active phase I would full focus on anti inflammation.

That said many of the substances mentioned are already anti inflammatory. Active phase I would apply anti-inflammatory applications as often everyday as possible and then every other day a DMSO+X mix that focuses on anti-calcification.(and in the settled hard plaque phase the other way around)

Ascorbic Acid is one..  Vitamin E..
Carnitine, Pentoxifylline, IODINE(!)
Colchicine - Molecular weight 399.437 g/mol sounds great for the active phase(lots of mixed or neutral studies about it with ORAL consumption, transdermaly, logically it has to be another-better animal!)
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 04, 2019, 02:06:07 PM
Vitamin K2(2 posts above) + Vitamin D3   
Vit D3: Molecular weight: 384.64 g/mol
Fat soluble

QuoteVitamin D3 and vitamin K2 ensure that calcium is absorbed easily and reaches the bone mass, while preventing arterial calcification.
QuoteMK-4 or MK-7 has a protective effect on bone mineral density and reduced risk of hip, vertebral and non-vertebral fractures.[7] These effects appear to be accentuated when combined with vitamin D and in the setting of osteoporosis.[1] The possible health benefits suggested for further investigation relate to bone strength and arterial health (reducing calcification or even decalcifying, with a possible reduction in blood pressure).

Too much of either one can deficiency the other one. I found a liquid Vit D3 + K2 combination mixed with MCT oil(coconut) which means the 2 fat soluble vitamins are already available. Quiet expensive though in that way than buying it in powder form..

Also Magnesium works together with D3 and K2 "activating" them. Couldn't gauge yet if I should mix the magnesium in. Probably smart to use magnesium before and after D3 and K2(same day)
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 04, 2019, 07:23:05 PM
Niacin Flush + DMSO
Molecular weight: 123.11 g/mol
Water soluable

To clean the plaque site from residue a transdermal Niacin flush every now and then might be a good idea. Maybe once a week.
Will be interesting to see if the niacin flush effect is transdermally only located where applied. If taken orally it can be all over the body..
QuoteNiacin Suppresses Progression of Atherosclerosis by Inhibiting Vascular Inflammation and Apoptosis of Vascular Smooth Muscle Cells.
Sounds great as the penis is full of Smooth Muscles cells. Also seems to target lipids which I understand can be part of a soft plaque.( I also think the plaque is hard around, like a shell, first and hardens outside inside.)
Title: Re: DMSO+X Revisited 2019
Post by: pap on November 07, 2019, 02:19:40 AM
Melting, what are your first impressions from daily application?
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 07, 2019, 12:57:33 PM
pap, the solution I created in post #5 I'm still using daily, sometimes 3-10 times. Skin is great.

The stability of the solution is great! No separation between oils and ACV and I added some Vitamin E capsules to it. I still shake it before application but the handling is so much easier than the original thackers formula. My solution doesn't drip which means I can move and sit around .

The tissue feels good. Very flush hang. Sometimes I can sense a warmth inside as if something is reacting.
The remaining plaque I have feels soft but I don't know if it already made a difference. But I'm sure it gets inside and reaches the plaque. Not much of it remains on the skin(I guess it's the emulsifier Xanthan and Lecitin.

I'm in the process of creating several more solutions as previewed above. My guess is that I need at least 6 weeks to make a statement if it changes the tissue and possible will take months to totally get rid of it.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on November 11, 2019, 12:43:22 PM
melting, I'm thrilled and happy for both you and for the sake of this forum. I really hope you come back in a few weeks with even more good results! These things are, like you and Tony covered earlier, stuff doctors and urologists would never even bother to consider when it comes to peyronies treatmenr.
That only shows that "home-treatment" can be and probably is the most effective way of treating this.
I have a question as well;
How do you mix your products? How do you mix the different liquids into one? For example DMSO + X + castor oil, like how do you mix these together? Hope that makes sense.
God bless you
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on November 11, 2019, 03:00:50 PM
And please, everybody who has used DMSO + X in whatever form. Please share your favorite remedies/combinations if you have any! I know there's an indefinite amount of combinations that PROBABLY could benefit our dicks. But again, please share your personal combinations and how it worked out for you.
God bless you all once again
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 11, 2019, 07:51:06 PM
Quote from: Godisreal on November 11, 2019, 12:43:22 PM
How do you mix your products? How do you mix the different liquids into one? For example DMSO + X + castor oil, like how do you mix these together? Hope that makes sense.

Before every mix we add the water to the DMSO. Could be anything from 10% DMSO 90% water to 95DMSO-5Water.
We do that cause DMSO has a heat reaction with water that is gone after it happened once.
We avoid DMSO to react on the skin(water) that way.

Most supplements are either fat or water soluble ("Supplement X + solubility" search in Google).

If fat soluble there's a good chance that you can mix DMSO+some water with Oil + fat soluble Supp X. Probably a bit of shaking needed before application.

If water soluble you could just mix it into the DMSO+water. You can until it's saturated.
You can then directly apply it to the penis with a glas eye dropper for example. Of course that's a very runny solution and you have to watch and hold your penis for 5-15 minutes until the DMSO is gone(into the skin).
You could then apply oil or a lotion after, cause DMSO tends to dry the skin.

What I do now is I add emulsifiers like described in post #5 to have a solution that doesn't sperate.
This way you can mix oils with supplements that are dissolved in water and it stays as one solution.
I wouldn't mix too many different supplements into one solution cause they can interact. Rather use several solutions and cycle them.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on November 11, 2019, 08:46:25 PM
I really appreciate your well put explanation melting. If the results are seemingly radical, why aren't more people trying this? Is it the lack of will? Lack of effort? lol seems crazy not to actually take time to learn and implement this technique.
Anyway, in what do you do these different mixes? A bowl? Or what do you suggest? Obviously you mix all these things in some kind of bowl? Or whatever? And then the glass eye dropper to apply with as you mentioned.
And could you please give a few examples on good supplements that come in liquid-form or that dissolve in water? Which also goes good with DMSO and potentially an emulsifier
I am doing research too as I'm writing this but I would love to hear a few from examples from you as well.
God bless you man and thanks again for sharing your experiences with the forum, I highly value that.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on November 12, 2019, 11:58:21 AM
I'm thinking on doing a mix with DMSO, olive oil and bone broth... along with water
Does this sound like a solid combination? Or are there anything else I should think about before going through with this? I know for a fact that bone broth and olive oil are both anti-inflammatory.
Btw, my goal is to reduce inflammation and, with time, soften my hard scar on the dorsal side of my dick. Peace
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 12, 2019, 01:39:21 PM
Brown glass from pharmacy with glass eye dropper.. Obviously don't use plastics for DMSO.
Please read my prior posts, I gave some examples of supplements.
Theoretically every supplement that can be taken orally, and is indicated for Peyronies Disease, and has a low molecular weight. (below and around approx 500g/mol)
Just search the oral medications forum for anti inflammatory supplements and then check on google their molecular weight. I would chime in if you post them here.


Now,.. Why wouldn't people do this?
Cause most wont do anything their doctor advises against.(I saw only 1 post here were a doc gave a DMSO type recipe). It requires a lot of DIY too and most people can't put a nail into the wall ;)
Also many did it wrong, in the other threads some burned their skin with DMSO(me too) So it creates a lot of uncertainty. It also might not work right away for various reasons. Needs faithful application of at least some weeks.
There are real dangers if you mix DMSO with harmful substances(poison, plastics, dyed fabrics..). So you need a lot of common sense and to be careful or it could end bad. Then again, I never was near any real danger handling DMSO for years and there's A LOT of info about DMSO around on google incl. scientific papers.

So you have to do your homework and apply common sense.
Which leads us to your idea about bone broth, sorry, lol. As I understand it's cooked animal bones and stuff? I wouldn't want to put that on my skin. I also think it's probably full of animal protein which has too big of a molecular weight for transdermals. Most supplements, Oils and also something like apple cidar vinegar are very controlled substances/supplements I would stick to.
Then again everything you do is your own responsibility and maybe bone broth is THE solution..

Like said in my initial post please read everything you can to understand what you're doing like this old thread which has all the pro's and cons and a lot of experiences: https://www.peyroniesforum.net/index.php/topic,39.0.html
Title: Re: DMSO+X Revisited 2019
Post by: dplookin on November 12, 2019, 03:00:12 PM
When I used DMSO, I used the Gel type with Aloe Vera.  I had no problem with it.  Just FYI  dplookin
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on November 13, 2019, 01:50:03 PM
dplookin, what brand of DMSO did you use? And did you experience any skin irritation? I can't find one brand that's doesn't warn for "KEEP AWAY FROM SENSITIVE SKIN"
Please evaluate your experience brother
God bless you
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on November 13, 2019, 02:45:43 PM
And also, thanks melting for taking your time and answering me. Really appreciate it!
I saw a lot of posts where people totally diminish the DMSO method, talking about how trash it is...
Seems to good to be true for me lol, can't say it's good or not since I haven't tried it.
But it would be foolish not to try it, eh? DMSO + Water + Castor Oil seems like a good place to start. But it feels wise to include some other drug/supplement with potential to reverse plaque forming or at least lower inflammation significantly...
Keep posting your thoughts and updates
- Godisreal
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 13, 2019, 08:14:11 PM
I would add Vitamin C a.k.a Ascorbic Acid to such a solution. Can't do much wrong with Vitamin C and it's very useful for what we try to do..
The only thing that can happen with Vitamin C is that it can stain the skin yellow after some time. But this goes away within days.

Ok, here's an example mix:
(This sounds like a long DIY but after doing it 2-3 times it's a 5 minute thing.)

You need:
-2 Brown glasses with a glass eye dropper(pharmacy) or another cap that isn't made of harmful plastics(https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/Product_Information_Sheet/d2650pis.pdf read - compatibility )
-Ascorbic Acid powder (In germany you can buy it in every big grocery store or pharmacy as pure powder)
-Castor oil(cold pressed! Internet or pharmacy)
-DMSO 99,99% quality (pharmacy or internet)
-A handheld kitchen mixer(or similar) Don't use it with the DMSO to avoid the DMSO dissolving plastic parts.
-An open container where you can mix the non DMSO parts with the mixer.
-Xanthan(Internet or grocery store)
-Lecithin(Internet, pharmacy or grocery store)

What I do with that:

-Clean area, no poison or other harmful substances that DMSO can transport into skin nearby.
-Put 100ml DMSO into the brown glass.
-Add some water(5ml..). Shake lightly. The solution will heat up. Just let it stay until cooled down.

-Mix and saturate 25ml water with ascorbic acid powder in an extra container. Just add the powder until it stops dissolving.
-Add 10 ml Castor oil. The oil and water wont mix!
-Add a small pinch of Xanthan and/or Lecithin to it. Then mix it thoroughly with the mixer. It will combine the oil with water.
The solution gets more solid the more Xanthan and Lecithin you add. Start small and keep adding until you're satisfied. If it gets too solid, add extra water which will make it more fluid.

-Fill the Brown glass that has the DMSO in it with the mixed solution. Shake the glass or mix it with something that doesn't react with the DMSO(I use a wooden Sushi stick). If the mix is too fluid you can add some water+xanthan solution.

Then test a small amount on your arm and wait an hour if there's a bad reaction.(if there's burning then you need more water and/or oil)
You can test and tweak the amounts. I found any solution with more than 90% DMSO will be tough on the skin.
I use a solution for like 2-3 weeks without problems. Beyond that many supplements will degrade.

Apply it as often as possible without having adverse effects(at least once a day) on your skin.
I apply the solution across my whole penis and sometimes focus more on where my plaque sits. Can be massaged in a bit.
Then I let it sit for 5-15 minutes. (like during my morning routine in the bath). I clean off all residue or apply some pure castor oil or natural/bio lotion..

This example mix, you can replace ascorbic acid with other supplements.
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 13, 2019, 08:19:14 PM
Quote from: dplookin on November 12, 2019, 03:00:12 PM
When I used DMSO, I used the Gel type with Aloe Vera.  I had no problem with it.  Just FYI  dplookin

Yeah that's very common mix sold on amazon etc.
I'm not sure if one could add/mix other, more effective, supplements too it.   
It could help on it's own I think it lacks a bit of a "punch"
Title: Re: DMSO+X Revisited 2019
Post by: pap on November 14, 2019, 08:39:52 AM
Great guide!  :)
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on November 14, 2019, 09:04:12 AM
melting, so you mean there's ready mixes to buy on amazon? DMSO + X?
It would save a lot of work to buy an already "finished" mix
Title: Re: DMSO+X Revisited 2019
Post by: dplookin on November 15, 2019, 12:39:03 PM
Godisreal.........Sorry for taking so long to get back to you.  The DMSO / Aloe Vera that I used is "Nature's Gift.  It is in a 4 oz container, and I'm sure I purchased it on Amazon.  I don't remember it causing any type of irritation.  Again, sorry for not getting back to you sooner.  dplookin
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on November 17, 2019, 12:50:05 PM
No worries man, it's easy to miss out on a comment. But I really wanna know what it did for you? Did you experience any improvements? Anything at all? I'm setting up a plan for how to tackle this... rn I'm only sticking with supplements and low-carb diet. And I'm too early into this to say if it's getting worse or getting better.
God bless you dplookin
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on November 18, 2019, 01:49:58 PM
Hey Melting! Or anyone with experience using these things. I've ordered a DMSO + Aloe Vera mix that will arrive shortly... you were talking about the mix missing that extra  "punch". What could you add into the mix, in order to add that extra punch? I'm starting experimenting as soon as I get it home. And should the DMSO + Aloe Vera mix be safe towards the skin? I think I've read about aloe Vera being very moisturizing.
Please answer as soon as you see this
- Godisreal
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on November 18, 2019, 02:16:02 PM
Most see DMSO as the transportation agent-you'll need to add the medication or supplement you believe will aid in remodeling the plaque.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on November 19, 2019, 09:05:55 AM
Thanks for chiming in Tony. Any suggestions in what I could add in to possibly re-model the plaque? I'm researching like a freak, but if you have any suggestions please let me know.
Beat regards, Godisreal
Title: Re: DMSO+X Revisited 2019
Post by: pap on November 19, 2019, 09:48:32 AM
DMSO by itself acts anti-inflammatory, antioxidant, analgesic, vasodilatory, wound healing and antimicrobial - that's what you can find.

I observed on me:
anti-inflammatory
pain-killing
softening plaque
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on November 19, 2019, 03:16:40 PM
That's great pap! And you only used the DMSO + Aloe Vera mix, if I understand it right?
I'm mentally chattered seeing me dick be deflated and crippled... I need to level up my treatment asap because my situation is absolutely ridiculous.
Keep updating here on this thread, lads. It really helps.
Peace
Title: Re: DMSO+X Revisited 2019
Post by: pap on November 20, 2019, 01:29:06 AM
Quote from: Godisreal on November 19, 2019, 03:16:40 PM
That's great pap! And you only used the DMSO + Aloe Vera mix, if I understand it right?

No I didn't. I mix DMSO with Magnesium chloride and apply Castor oil afterwards to avoid drying.
Cialis in low dose (2.5mg) was also helpful to restore the blood circulation. Now I still have small lumps, but no problems.

There is not "the solution" to this sickness, I guess if someone comes with a simple treatment -> $$$
Be patient and gentle to your friend ;-)
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 20, 2019, 04:32:44 PM
Quote from: Godisreal on November 18, 2019, 01:49:58 PM
I've ordered a DMSO + Aloe Vera mix that will arrive shortly... you were talking about the mix missing that extra  "punch". What could you add into the mix, in order to add that extra punch? I'm starting experimenting as soon as I get it home. And should the DMSO + Aloe Vera mix be safe towards the skin? I think I've read about aloe Vera being very moisturizing.

My thought process is that the Aloe vera mix saturates the DMSO. 
This could mean anything else you add won't go transdermal as easily.
I wouldn't add anything extra to that but rather create another mix of DMSO+X.(you got several recomendations in this thread)

The DMSO+Aloe mix is probably the safest and skin friendliest DMSO mix you can buy.
I add Castor oil to my mixes cause it's great for the skin and mitigates possibly drying out from the DMSO(I wrote about castor oil on this thread prior)

As pap said, the DMSO alone can help and Aloe has some healty properties too.
I think other supplements like Ascorbic Acid etc.(I mentioned a lot prior) can give more "punch", as in more impact at the plaque site.

What I advocate for is to "flood" the Penis tissue at and around the plaque with supplements that are said to help with peyronies plaques, scar tissue,fibroids etc. 
The ways I described prior in this thread are in my opinion great to achieve that...

..I now have 6 different mixes that I apply at least 2 times a day.(sometimes all day every 30 minutes)
I circle them to "attack" the plaque from several "chemical angles". Mostly I focus with every application on one mix and use another with the next application(or day).
My skin is great(thx to castor oil in every mix) and the tissue feels very healthy and I "hang flushed".
The plaques are again feeling very soft. Soon I will start pumping, stretching etc. to stretch the tissue around it.
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 20, 2019, 04:49:05 PM
(DMSO+X) + Traction/VED/Tissue Modeling

I see big potential in combining both at the same time or in succession.

When using DMSO at the same time as traction or VED devices,.. you should be careful that the DMSO+X solution doesn't interact with plastics and metals while applied to your skin 

Using my VED I wrap the tissue lightly with a clean white cotton cloth over the area where I applied the DMSO+X to avodi any DMSO contact with the plastic of the VED.

The often observed softening of the plaque while using the DMSO+X is good but when you stretch the plaque, it can be a) easier stretched and b) the stretching could enable the DMSO+X to easier penetrate the plaque(for example microtears in the plaque).
Title: Re: DMSO+X Revisited 2019
Post by: dplookin on November 21, 2019, 09:25:56 AM
Godisreal..........I saw no change after using the DMSO with Aloe.  I have been working on trying to solve my problem for years and have gotten no where.  I have tried just about everything you can think of and nothing seems to help including Years of Traction and Years of VED, which I am still doing.  You can try the DMSO and Aloe, it may help you.  I lost 2 to 3 inches in length and have a 80 to 90 degree bend to the right.  Different things help Different People.  You need to give it a try.  I wish you Luck, and Sorry again for taking to long to get back to you.  Take Care, dplookin
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on November 21, 2019, 10:57:38 AM
Thanks for all the input guys, really appreciate it.
I'm very sorry to hear about your situation dplookin.
When you say you lost inches, do you mean you lost inches because of the severe bend?
How else would you lose length?
Hope you find yourself curing soon man, we all should cure one day.
God bless you
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 22, 2019, 05:24:54 AM
Please keep on topic DMSO + X to get good info collected.

DMSO+Aloe is great for the skin but I think the plaques need more active substances(as described prior) to soften and dissolve.
My guess is 1-2 times a day DMSO+Aloe won't do much to the plaque.
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on November 24, 2019, 10:51:02 PM
I agree, DMSO is only the carrier...need to add a therapeutic element.
Title: Re: DMSO+X Revisited 2019
Post by: buzzin2 on November 30, 2019, 12:10:43 PM
i dunno if i have some sort of injury or if i have pre peyronies, i went to the uro 3 times and they're annoyed with me and said nothings wrong.  im thinking of doing this dmso thing, would it be beneficial if im in acute stage?  i know it dissolves plaque but i dunno if it is beneficial if plaque hasn't formed.  at the same time i figure the dmso would penetrate and whatever else you add with the dmso would get right ot the tissue and heal.  so i figure this would also help for a general penis injury, what do you think?
Title: Re: DMSO+X Revisited 2019
Post by: melting on November 30, 2019, 03:58:03 PM
Alright, several weeks in now and feeling great. Very flush, great hang, good circulation. Faulty tissue is very soft.
Clear difference to before applying DMSO+X but difficult to say if the faulty tissue is shrinking though.
I think the little bit of indentation I have is filling in better, especially days where I'm pumping.
Prepared to do this until it's fully dissolved. Surely will take some more months of daily application...


Quote from: buzzin2 on November 30, 2019, 12:10:43 PM
im thinking of doing this dmso thing, would it be beneficial if im in acute stage?
Sure, just focus on using anti-inflammatory supplements as X.

For example,.. DMSO + Iodine. DMSO + Vitamin E. There's more.. not my focus right now.. Just search for acute stage supplements and if you can use them with DMSO (compatible - molecular weight - I wrote about it prior page). You can list them here and I chime in.

You can't do much wrong in any stage by doing DMSO+Ascorbic acid(vitamin C). Hell, I would do it from time to time If I was healthy just to clear the tissue, arteries etc.

Read the first 1-2 pages on google about DMSO, this thread etc. to understand how to handle DMSO.
I wish I knew what I know now when I had the first Peyronies Disease symptoms.
Title: Re: DMSO+X Revisited 2019
Post by: buzzin2 on November 30, 2019, 06:16:26 PM
thats an awesome reply, thx

im reading that entire, long ass 10 page dmso thread from 2005.
Title: Re: DMSO+X Revisited 2019
Post by: melting on December 04, 2019, 07:07:35 PM
All the talk about Aloe made me take some Aloe juice from the drugstore.   
I added the Aloe Vera juice to all the mixes. Just some drops. Can't hurt and it seems to improve the texture of the mix and feeling of skin after.   

I'm not sure about Aloe's impact in itself +DMSO. But there are several claims around that it helps with scars and fibrous tissue..
This is a nice compilation about Aloe:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763764/
A long list of healthy ingredients found in it.. many of them with low molecular weight.

Writing this I think it might be a good idea to have a DMSO+Aloe Vera mix in the circling of the various DMSO+X solutions. It certainly is great for the skin.
Title: Re: DMSO+X Revisited 2019
Post by: melting on December 04, 2019, 07:18:10 PM
Shelf Life of the DMSO+X solutions..

DMSO + Vitamin C degrades rather fast for example. After 10-21 days the Vitamin C turns orange/yellow and into a "lesser biologically usable form".
Changing of smell is another indicator of degradation.
Observe changes and if in doubt just get rid of it and make a new batch.

What I do often is to add to my mixes fresh ingredients instead of making a new one. Takes some experience though.
Surely after some weeks any glass should be emptied, thoroughly cleaned and a new mix made.
Title: Re: DMSO+X Revisited 2019
Post by: buzzin2 on December 04, 2019, 08:03:55 PM
do you just order dmso on amazon?  any reliable brands?
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on December 05, 2019, 10:33:12 AM
melting, is your plaque calcified? I seem to be the only one with a calcified thin scar, not a plaque.
I wonder if I will have the same success with DMSO anyway...
Title: Re: DMSO+X Revisited 2019
Post by: melting on December 05, 2019, 06:31:35 PM
Quote from: buzzin2 on December 04, 2019, 08:03:55 PM
do you just order dmso on amazon?  any reliable brands?

Several online shops in germany I ordered from over the years incl. amazon. Always satisfied..
I  read that jacoblab in the US is one of the best sources but so might be anyone with good reviews. Pharmacies or chemical supply stores might have good quality. Due diligence..

Quote from: Godisreal on December 05, 2019, 10:33:12 AM
melting, is your plaque calcified? I seem to be the only one with a calcified thin scar, not a plaque.
I think it is calcified but softens after some days/weeks with DMSO.
It's a fibrous plaque that then gets en-capsuled and hard/calcified.
I think scar tissue can be positively impacted by DMSO+X too. I applied it to some smaller old scars on my legs and they soften too and then scab and turn more "fleshy"/pinker. You can try and observe... If you search Vitamin C + scars you'll find a lot on google and so might be other supplements.. ( search "X + scar tissue")
Title: Re: DMSO+X Revisited 2019
Post by: buzzin2 on December 06, 2019, 02:00:49 PM
i should get the 99%+  pure dmso right?
Title: Re: DMSO+X Revisited 2019
Post by: melting on December 08, 2019, 09:00:53 PM
Right, 99,99% pharmaceutical grade DMSO. 
DMSO is a well researched product, used everyday in countless laboratories around the world.
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on December 09, 2019, 04:28:44 PM
Doesn't one dilute DMSO for use?
Title: Re: DMSO+X Revisited 2019
Post by: melting on December 10, 2019, 03:41:00 PM
Yes: https://www.peyroniesforum.net/index.php/topic,12587.msg116215.html#msg116215
Title: Re: DMSO+X Revisited 2019
Post by: melting on December 18, 2019, 12:24:58 PM
One thing,.. if you use DMSO+Ascorbic Acid(Vitamin C) a lot then the skin might turn yellow/orange there.   
That's ascorbic acid trapped/accumulating in the skin layers "decaying". It goes away after some days not using Vitamin C.

I did now run through at least 1 batch of every mix but always have a big DMSO+Ascorbic Acid mix which I now run for a week straight 3-10 times a day and this visual gets apparent fast. Didn't happen when I cycled several mixes.

My tissue feels great. The hard sites feel now very soft but are still there. But the overall health of my penis is great. I'm having a very "flush" meaty hang all day everyday. Great blood circulation.
Title: Re: DMSO+X Revisited 2019
Post by: melting on December 30, 2019, 07:07:31 AM
How to proceed after applying DMSO+X

It's recommended to let DMSO+X sit for at least 10 minutes. After 15 minutes most of the DMSO should be gone.
Depending on the "X" you wash it off, rub in the remains or apply an oil or a(healthy/bio) lotion over it. Ascorbic acid/vitamin C for example will stain clothes yellow/orange.
If I'm just around at home I will let it sit and wear some white cotton underwear that I don't worry about.
Just apply common sense. Don't wear heavily colored toxic underwear after applying DMSO ;)

Title: Re: DMSO+X Revisited 2019
Post by: samsung on December 30, 2019, 08:31:42 AM
After the 15 minutes of letting it sit and then washing off, can you put on heavily colored underwear then?
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 03, 2020, 06:03:54 PM
Yes, if there's no DMSO on your skin interacting with the underwear, nothing should happen.
Title: Re: DMSO+X Revisited 2019
Post by: desmondthethird on January 05, 2020, 11:36:17 AM
Irishpeyroniecure, what else does your "cure" contain of?
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 05, 2020, 12:35:19 PM
Please don't clutter this thread with posts that have no value to others or add to the context of this thread, irish.
This is not a chat were you post several posts in succession. Please also don't answer to this post in this thread either.
(If a mod reads this please delete above posts and this one)
desmond, if you check his profile https://www.peyroniesforum.net/index.php?action=profile;u=22162 he has made some posts detailing his cure. It's in no relation to this thread though.
Title: Re: DMSO+X Revisited 2019
Post by: samsung on January 05, 2020, 01:31:46 PM
This Irish guy has also called everyone here losers and said a transexual member is better off dead. Great guy. I'm sure all the rest of his posts are extremely worthy of being read by rational humans. He advocates marijuana and steroids too. Awesome.
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on January 05, 2020, 08:19:02 PM
I agree Sam, and when he said those things I requested he STOP!
Title: Re: DMSO+X Revisited 2019
Post by: Hawk on January 06, 2020, 12:28:35 AM
Quote from: Irishpeyroniecure on January 05, 2020, 11:24:18 AM
Pfff...I have the only solution. Infrared and a few other gems

How absurd for someone to claim they have the only answers.  My experience with Peyronies Disease and life, in general, is that the more loudly a person proclaims they have the answer, the more ignorant they appear when you take a closer look.
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 06, 2020, 05:28:16 AM
Oh cool derailment of another thread so people have to wade through empty useless posts. The scourge of most forums on the internet.
Anyways..

DMSO + PENTOX

I got my hand on some Pentox from a relative. I crushed it, added some water and used the mixer.
There will be some left over materials which is most probably the filler from the tablet. I looked them up and they're harmless.(again: test every solution you make first on your arm with some drops) One could probably filter them out but that needs some research to make sure the pentox doesn't get filtered too. If you don't filter them they will remain on the skin if their molecular weight is high.

Molecular weight of Pentox: 278.31 g/mol
This means it's perfect for transdermal delivery with DMSO.

Pentox has various impacts on Peyronies Disease, it enables red blood cells to be more flexible which means they can get into places they couldn't before(scars, fibroids?). That is a rather systemic mechanism which can be easily created by oral medication but it also has effects that can work right in place..
It inhibits the formation of inflammatory agents.
For people out of the active phase it has still a function like inhibiting TGF-beta which is part of scar tissue and fibroids.
QuotePentoxifylline increases fibroblast collagenases and decreases the production of collagen, fibronectin and glycosaminoglycan.
It basically aids the production of healthy collagen and messes with the faulty collagenous fibroid structures of peyronies plaques.

I did use the same protocols to create an easy to apply solution like you can read about on the previous pages. 
Considering the amounts possible to apply transdermaly I don't worry much about dosage. I managed to dissolve about 8 tablets in a vial that would take me around 2 weeks to go through with 3 times a day applications. (now still be aware of how much Pentox you put into a given mix)



Title: Re: DMSO+X Revisited 2019
Post by: goodluck on January 08, 2020, 11:22:41 AM
Can anyone comment on what DMSO's shelf life would be.?    I have a bottle that is about 7 years old.  It does not say on the label.  It does say if cloudy do not use.  It is not cloudy.  It looks and smells normal to me.  Just wondering if it loses something over time.  Thanks.
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 09, 2020, 11:00:45 AM
Depending on how it was stored about 2-5 years. If it's in the original storage container dark and cool it might still be good.. I wouldn't use it if it was some sort of premix and not the pure dmso.
I don't know how DMSO breaks down but DMSO will freeze/solidify in the refrigerator above 0°c / 32°F. If it doesn't do that anymore I'm sure it lost it's properties. I couldn't find a definite answer through several google links. DMSO is cheap. So if you have a good source, you might buy a new bottle.
Title: Re: DMSO+X Revisited 2019
Post by: john.doe.550 on January 10, 2020, 02:16:30 AM
There is a ton of info in this posted topic, with DMSO central to the conversation in terms of a carrying agent.  DMSO is an organosulphur compound (Dimethyl sulfoxide). Its formula is  (CH₃)₂SO.  That's carbon, hydrogen, sulphur, and oxygen. I'm emphasizing this due to the sulphur in this compound.

I'm allergic to sulphur and, especially, sulfa drugs. Sulfa prescriptions mess me up big time.  About 25 years ago, I used DMSO to transport a very high quality powdered vitamin mixture through my skin.  After 2 or 3 days, I had allergic reactions to the sulfur in the DMSO.  The primary symptom was pounding headache.  A secondary symptom was flushed or reddened face.  I stopped using DMSO and re-tried it again in 2 weeks.  Same symptoms were experienced.  I didn't use it again.

I share the information contained in this post to alert others they may experience similar symptoms.  Fortunately, not many people are allergic to sulfa drugs. But, if you are allergic to sulfa drugs and/or feel poorly using DMSO, then you are not alone.
Title: Re: DMSO+X Revisited 2019
Post by: AlterEgo on January 10, 2020, 04:17:57 AM
Is it ok to use dmso + absorbic acid while on a dry fast and water fast?
Title: Re: DMSO+X Revisited 2019
Post by: sinvanio13 on January 10, 2020, 02:09:50 PM
Hi,
looking for dmso on amazon us  , there was a dmso cream said for Dupuytren's syndrom what do you think about it?
thanks
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 10, 2020, 04:01:39 PM
Quote from: AlterEgo on January 10, 2020, 04:17:57 AM
Is it ok to use dmso + absorbic acid while on a dry fast and water fast?
I see no reason why not but I have no experience with "fasts".
Quote from: sinvanio13 on January 10, 2020, 02:09:50 PM
dmso cream said for Dupuytren's syndrom
I don't know what cream you are talking about(you can send me the link via pm, don't post here). It's a similar disease so it might work.
Title: Re: DMSO+X Revisited 2019
Post by: sinvanio13 on January 10, 2020, 04:34:12 PM
Quote from: melting on January 10, 2020, 04:01:39 PM
".I don't know what cream you are talking about(you can send me the link via pm, don't post here). It's a similar disease so it might work.
pm sent ;)
us amazon website +"health and beauty"  search  for "Dupuytren's"
Title: Re: DMSO+X Revisited 2019
Post by: sinvanio13 on January 13, 2020, 09:45:35 AM
Hhi,
i found an interesting protocole on  vitamine wiki , about Dupuytren's and Mg,D3, Dmso , Boron , Aloe vera
not sure i am allowed to post url links but it's not a commercial one , have a look seems to be relevant about that topic
copy the whole link in your browser because clicking on it not going to the right page , perhaps beacause of the "+" symbols at its end


https://vitamindwiki.com/Dupuytren's+Contracture+%28bent+finger%29+treated+by+Boron+and+DMSO+-+2016

https://vitamindwiki.com/tiki-index.php?page_id=7967 is the same page
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 13, 2020, 02:16:44 PM
Great find! D3 and MG I talked about earlier. Interesting is that they together with Boron seem to have synergistic effects.
Always interested in combining several supplements. I'm running 5 different glasses of DMSO+X right now.

Reading the article on your link it's clear how much more effective transdermal is. Person had no reaction to oral Boron initially.

BORON:
Molecular Weight: 10.81 g/mol
That is very low! Could get a lot of it through the dermal layers via DMSO..
But I'm unsure about it's solubility and toxicity especially in combination. Then again it seems to be readily used in some preparations.

QuoteUnder normal circumstances boron does not react with water. However, for boron compounds may be the case. Boron salts are generally well water soluble. Boric acid has a water solubility of 57 g/L, borax of 25.2 g/L, and boron trioxide of 22 g/L. Boron trifluoride is the least water soluble boron compound, with a water solubility of 2.4 g/L.
Obviously mixed with MG it might change the solubility.

Quote
General: There is no Recommended Daily Allowance (RDA) for boron since an essential biological role for it has not been identified. The Tolerable Upper Intake Level (UL), the maximum dose at which no harmful effects would be expected, is 17 mg per day for adolescents

From your link:
QuoteBoric/Boric Acid (10 mg dailyseems to work),

QuoteIt has been shown that boric acid has well-defined biological effects such as stimulation of wound healing in vivo, release of growth factors and cytokines, and increase of the extracellular matrice turn-over
https://link.springer.com/article/10.1385/BTER:85:1:23
A lot of impact on fibrosis talked in several studies. Also impact on collagen formation and angiogenesis. Both crucial in peyronies.

I will buy some boron and check how it reacts in my DMSO+X mix and then combine it with D3 and magnesium. Instead of aloe I'm using mostly Castor oil.
Title: Re: DMSO+X Revisited 2019
Post by: sinvanio13 on January 13, 2020, 03:03:36 PM
Quote from: melting on January 13, 2020, 02:16:44 PM
Great find! D3 and MG I talked about earlier. Interesting is that they together with Boron seem to have synergistic effects.
Always interested in combining several supplements. I'm running 5 different glasses of DMSO+X right now.

Reading the article on your link it's clear how much more effective transdermal is. Person had no reaction to oral Boron initially.

BORON:
Molecular Weight: 10.81 g/mol
That is very low! Could get a lot of it through the dermal layers via DMSO..
But I'm unsure about it's solubility and toxicity especially in combination. Then again it seems to be readily used in some preparations.
Obviously mixed with MG it might change the solubility.
thank you another interesting link below  where it's said :

"The doctors of PDI and DCI wanted to use a DMSO product that contained several synergistic products that could be helpful for DC.    They soon learned that the discoverer of DMSO, Stanley Jacobs, MD, has been using a special formula of DMSO, vitamin E, methyl salicylate and urea for his own patients with great success.  To make it easy and economical to apply, he made the formula into a gel formulation.  Dr. Jacobs called his special DMSO formula DUSA-SAL Gel.  When used twice daily it can be effective, and when combined in a larger therapy plan such as described by DCI the results can be just that much better.  This particular product, Dusa-Sal Gel, was selected for use by DCI because of the encouraging reports and research behind each therapy. Our opinion is that this combination is a good way to get as much additional therapy into the local area of the lesion area as possible. We think you will not find a more effective, pure and safe DMSO product than Dusa-Sal Gel anywhere."
where is also a link to that famous dmso preparation

Dupuytren Contacture and DMSO - Dupuytren Contracture Institute (http://dupuytrens-contracture.com/dupuytren-contracture-treatment-options/dupuytren-contacture-dmso/)

Quote from: melting on January 13, 2020, 02:16:44 PM
BORON:
Molecular Weight: 10.81 g/mol
That is very low! Could get a lot of it through the dermal layers via DMSO..
But I'm unsure about it's solubility and toxicity especially in combination. Then again it seems to be readily used in some preparations.
Obviously mixed with MG it might change the solubility.
From your link: https://link.springer.com/article/10.1385/BTER:85:1:23
A lot of impact on fibrosis talked in several studies. Also impact on collagen formation and angiogenesis. Both crucial in peyronies.
I will buy some boron and check how it reacts in my DMSO+X mix and then combine it with D3 and magnesium. Instead of aloe I'm using mostly Castor oil.
for the boron dosage he said :"Update Nov 13, 2016
Well now, that did not work!
Hand ached all of Nov 12.
Suspect that there was less Boron in the DMSO slurry due to having the MgCl
I have switched back to Boron + DMSO. No pain again
I have also purchased 1 lb of Boric Acid crystals from Amazon
Realized that I had been applying approximately 1 milligram of topical Boron at a time
Going to make my own Boric acid solution and see what happens when I apply 3 or so mg at a time."
Title: Re: DMSO+X Revisited 2019
Post by: aquintance22 on January 13, 2020, 03:35:45 PM
Anyone has tried DMSO + Serrapeptase or other enzymes or would it be not absorbable or only working in the intestines?
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 13, 2020, 04:55:46 PM
Serrapeptase

Molecular Weight‎: ‎345.9 g/mol
Should work. For some reason I made a post years ago declaring it has too high of a weight. Turns out Nattokinase, similar enzyme, is around 600g/mol which is rather big.

https://www.ncbi.nlm.nih.gov/pubmed/20582192
QuoteSerratiopeptidase, an enzyme derived from Serratia marcescences strain E-15 (ATCC 21074), present in the gut wall of the silk worm possesses anti-inflammatory properties, and can prove to be a suitable alternative to commonly used non steroidal antiinflammatory agents. Being sensitive to gastric degradation, serratiopeptidase is conventionally given orally in the form of enteric coated tablet formulations. Topical formulations of serratiopeptidase would be useful to treat local inflammations and may prove to be more effective compared to non steroidal antiinflammatory agents.

Quote
Solubility
Soluble in water forming a clear solution practically insoluble in alcohol and in solvent ether

I read it's quiet ineffective orally taken but there's some studies, especially asian, were it's proven to have an effect on fibrosis and scars.
So yes, another one to try with DMSO
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 13, 2020, 05:15:00 PM
Quote from: sinvanio13 on January 13, 2020, 03:03:36 PM
Suspect that there was less Boron in the DMSO slurry due to having the MgCl
I have switched back to Boron + DMSO. No pain again
Yeah, to make sure the ingredients actually work I opted to use just 1 in every DMSO+X formulation and cycle them daily or with each application.
Of course quiet a hassle to have 10 brown glasses standing around and replacing them when they run out.
Quote from: sinvanio13 on January 13, 2020, 03:03:36 PM
Dr. Jacobs called his special DMSO formula DUSA-SAL Gel.
They still sell that at jacobs labs.
https://jacoblab.com/!!!!!!!!!!!OrderDMSODusaSAL.html (remove-!)
Would be more convenient to apply DMSO+X formulations with a gel type carrier. Though I love to use castor oil(which is the carrier) as itself has many possible helpful agents in it and is great for the skin(but can smear clothes).
Methyl salicylate:
Molecular Weight‎: ‎152.15 g/mol
QuoteMethyl salicylate is used in high concentrations as a rubefacient and analgesic in deep heating liniments (such as Bengay) to treat joint and muscular pain. Randomised double blind trials report that evidence of its effectiveness is weak, but stronger for acute pain than chronic pain, and that effectiveness may be due entirely to counterirritation. However, in the body it metabolizes into salicylates, including salicylic acid, a known NSAID
Nonsteroidal anti-inflammatory drugs (NSAIDs) are members of a drug class that reduces pain, decreases fever, prevents blood clots, and in higher doses, decreases inflammation. Side effects depend on the specific drug but largely include an increased risk of gastrointestinal ulcers and bleeds, heart attack, and kidney disease.
Not sure about that.

Urea:
Molecular Weight‎: ‎60.056 g/mol
There's lots of info about Urea helping with scars. Often used in cremes etc. so certainly could be a great addition.
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 13, 2020, 05:25:28 PM
Btw. regarding MOLECULAR WEIGHT.

It's proven that Insulin can't be used with DMSO to go transdermal. Insulin has a Molecular Weight‎ of: ‎5808 g/mol
Hard to say at what exact molecular weight the cut off point is but it seems to be below 1000 g/mol and I assume the higher the weight the less is transported transdermaly.
Ascorbic Acid with 176,12 g/mol is perfect and I can literally feel it going inside. Heck my penis sometimes gets yellow patches from the vitamin C pooling through the deeper skin layers. Saying that it especially pools for some reason in nails, so take care if you want to avoid the look, but nothing dangerous about it. Some days off and the body takes it all up.
Title: Re: DMSO+X Revisited 2019
Post by: sinvanio13 on January 14, 2020, 10:11:32 AM
Quote from: sinvanio13 on January 10, 2020, 04:34:12 PM
pm sent ;)
us amazon website +"health and beauty"  search  for "Dupuytren's"
i had been in contact with the customers service (via their website) for they cream and they kindly reply "We actually experimented with DMSO but it was to harsh of a solvent and we found aufficient absorption using natural ingredients.  "   so for Dupuytren's , but they said Peyronies Disease and Dupuytren's are quite similar
and they would be interested by any feedback ,
they are delivering only for usa residents 


Title: Re: DMSO+X Revisited 2019
Post by: sinvanio13 on January 14, 2020, 10:18:44 AM
I found that interesting study with Geranium essential oil (the Bourbon one) Perargonium Asperum

Suppression of neutrophil accumulation in mice by cutaneous application of geranium essential oil:
https://journal-inflammation.biomedcentral.com/articles/10.1186/1476-9255-2-1
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 14, 2020, 04:07:44 PM
Quote from: sinvanio13 on January 14, 2020, 10:18:44 AM
I found that interesting study with Geranium essential oil (the Bourbon one) Perargonium Asperum
Suppression of neutrophil accumulation in mice by cutaneous application of geranium essential oil:
https://journal-inflammation.biomedcentral.com/articles/10.1186/1476-9255-2-1
Sounds like an interesting option for fresh penis injuries or early stage of peyronies.
Geranium essential oil
Molecular Weight:   154.25 g/mol

QuoteEssential oils are soluble in alcohol, ether, and fixed oils, but
Quoteonly slightly soluble in water
.
So you would up the oil parts in such DMSO+Geranium essential oil mix. I would still add some water to react with the DMSO to get rid of the heat reaction.

Title: Re: DMSO+X Revisited 2019
Post by: sinvanio13 on January 14, 2020, 04:47:30 PM
Another interesting link :
Off topic: Transcutaneous enhancers (DMSO, etc) for Vitamin D, Vitamin C, Resveratrol, Magnesium, etc :
" Notes by Henry Lahore, founder of VitaminDWiki
I have successfully using low concentration DMSO in an aloe vera gel on my skin to get Magnesium and Boron into my body
Dupuytren's Contracture (bent finger) treated by Boron and DMSO - 2016
  (alreay shared by myself)

The Dupuytren's becomes bothersome several times a year and goes away each time after 2 treatments
Magnesium Chloride water/oil added to DMSO cream treats sore muscles in about 10 minutes


239 products on Amazon for Transdermal Magnesium as of April 2019
The only one I tried caused my skin to rash after about a month, so I gave it up and made my own
I needed more than Vitamin D to treat my knee osteoarthritis Magnesium and Low Level Laser Therapy
In April 2019 I got a painful shoulder which I assumed was Calcium deposits, similar to my wife's which were diagnosed by MRI
I found a reference on the web to the use of an acid (Ascorbic Acid) to disolve Calcium

After just a few days my shoulder pain appears to have gone away

Calcium deposits melted by Ascorbic Acid and DMSO – 2010
He believes that that the slight acidification of the region under the skin disolved the Calcium deposits

The author describes exactly what he did to get his shoulder pain to go away
Interesting to note - after a few months his pain came back, and quickly went away after re-application of the mixture

Note: Suspect that my Vitamin K (Super K LEF) did not keep Calcium from accumulating in my soft tissues
Hard bones, soft arteries, rather than vice versa (Vitamin D and Vitamin K) – March 2016
Another person switched from Super K to another supplier and was able to remove Calcium which had bulit up in his artiries while taking Super K. I need to investigate (May 2019) "


https://vitamindwiki.com/tiki-index.php?page_id=10721

sources from : "The 500 Dalton Rule of Dermal Penetration and Cosmetic Science March 2017"
https://realizebeauty.wordpress.com/2017/03/27/cosmetic-science/
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 14, 2020, 06:31:57 PM
Yes all good links and supplements. 
I think I listed them all already in this thread(Reservatrol has not much use in peyronies).
Used DMSO+Vitamin K2-MK7 just today.

The basic and best in any case is Ascorbic Acid. Can't do much wrong with it and it has several impacts on plaques, tissue and the healthy formation of collagen.
Title: Re: DMSO+X Revisited 2019
Post by: sinvanio13 on January 15, 2020, 06:45:19 AM
Quote from: melting on January 14, 2020, 06:31:57 PM
Yes all good links and supplements. 
I think I listed them all already in this thread(Reservatrol has not much use in peyronies).
Used DMSO+Vitamin K2-MK7 just today.

The basic and best in any case is Ascorbic Acid. Can't do much wrong with it and it has several impacts on plaques, tissue and the healthy formation of collagen.
thanks for your "scientific" work and experimentations , of course for your sharings ;)
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 15, 2020, 02:05:13 PM
No worries, I love people chiming in, adding info. Any thread at some point will get double info etc. 
I hope some more people try it and we can learn and optimize this and then boil the info down in a new thread.

I'm now almost 2months in and my penis feels great, the plaques are soft and I imagine they're slowly getting smaller. I'm 100% sure that if I had never stopped applying DMSO+X years ago I would've no plaques or faulty tissue at all long ago.
No adverse effects at all and I did run aroun 10 different mixes since November. Anyone reading this thread and some links on google should be able to do it.
But I'm sure it can get easier, as in nailing down the exact amounts of the ingredients and finding the right X-supplements for different cases and stages of peyronies.
Title: Re: DMSO+X Revisited 2019
Post by: sinvanio13 on January 16, 2020, 10:31:32 AM
For the oil part :
i read many articles it seems that, for mixing with essential oils(of course choose organics , first mechanics extraction, virgin oils ) :

1) the chestnut oil is one of the most penetrating  oil into the dermis and hypodermis
(so for muscular et joint massage ) a downside quite easily oxydable and not convenient for people subjects
to allergies with nuts

2) Macadamia is good also for dermis penetration but very oxydable,expensive, same worry about allergia

3) Jojoba is a good compromise , quite well penetrating dermis and not oxydable( 10 years ! lifespan)

4) Arnica's Macerate is quite good but depend on the base oil quality (sunflower) dangerous by oral
intake( cadiac worries , so long term effects for massages ?)

5) Aleurites triloba ou Aleurites moluccana (KUKUI) very penetrating but very oxydable (worry from allergy ?, Euphorbia family plant)

6) Camelina sativa (camelina) very penetrating and oxydable(so should be mixed with jojoba wax for example)

7) Argan oil : quite good for penetrating (plus has E. Vitamine ) but expensive

8) Grape seed oil (Vit E & polyphenols (OPC) ) easyly oxydable affordable well penetrating .

9) Castor oil (not from animal but seeds ^^ ) : is toxic by oral intake , so long term use with dmso?   

hoping it will help
Title: Re: DMSO+X Revisited 2019
Post by: desmondthethird on January 17, 2020, 07:42:07 AM
sinvanio, I'm personally gonna start DMSO + Aloe Vera treatment as soon as the delivery comes, I'm gonna apply Magnesium Oil first then apply DMSO + Aloe immediately afterwards, this combo comes on 2-3 times a day.
Title: Re: DMSO+X Revisited 2019
Post by: sinvanio13 on January 17, 2020, 09:09:45 AM
Quote from: desmondthethird on January 17, 2020, 07:42:07 AM
sinvanio, I'm personally gonna start DMSO + Aloe Vera treatment as soon as the delivery comes, I'm gonna apply Magnesium Oil first then apply DMSO + Aloe immediately afterwards, this combo comes on 2-3 times a day.
hello, i am thinking about that kind  of protocole , because easier, in a first time, i guess your dmso+aloe is the one on Amazon, with rose scent , did you check the composition for the rose scent etc?
Title: Re: DMSO+X Revisited 2019
Post by: desmondthethird on January 17, 2020, 11:12:30 AM
Mine does not have rose scent, feels like it would be trashy chemicals in that rose scent.
Mine is 99 pure DMSO mixed out with Aloe Vera, then I'll be buying Magnesium Oil on top of that.
Treatment will start within a week. I'm having high hopes for this, man, it's crazy.
- Desmond
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 17, 2020, 01:53:07 PM
I agree the protocols I present on page 1 need some preparation, several ingredients and stuff like a mixer, several brown glasses etc. Takes me 5-10 minutes to create a mix these days but it got very messy when I did the first few..

Quote from: desmondthethird on January 17, 2020, 07:42:07 AM
I'm gonna apply Magnesium Oil first then apply DMSO + Aloe immediately afterwards, this combo comes on 2-3 times a day.
That's a good idea with the supplements you have available.
Another one you should try is buying pure Ascorbic Acid(vitamin c) powder which is very cheap. It's available in every grocery store, at least in Germany for ~5€, but should also be on amazon or in a local pharmacy. Ascorbic Acid, IMO, should be a staple during every stage of peyronies. It's almost impossible for it to hurt while having a lot of good properties(written prior about it).

-You take a cup of clean water. I use tapwater and boil it once(then let it cool) but if you have bad tapwater quality you might buy distilled water.
-Then you fill that cup with some spoons of Ascorbic acid and stir it until the powder is dissolved. You add powder until the water is saturated(= more powder added doesn't dissolve anymore).
-Then you cover your penis or the plaque area with it and put the DMSO+Aloe creme over it. That's obviously a bit messy but still could do the trick to transport some Vitamin C directly to the area. 1-3 times a day or more.
Be aware that Vitamin C once dissolved in water will only stay stable for 1-2 weeks.(it will turn orange over time)

QuoteI'm having high hopes for this, man, it's crazy.
I hope for the best and if that dmso+aloe mix is able to transport some of the magnesium and/or vitamin c to the area you should see some improvement within days or weeks.
Observe the skin and cut applications back if it gets redness and apply some lotion.

But as I said often it's not a one trick pony and you might have to do more like traction etc. later.
I also have no personal experience with the DMSO+Aloe mixes. But theoretically it should/can work.
Title: Re: DMSO+X Revisited 2019
Post by: melting on January 24, 2020, 10:57:12 PM
Alright guys, you know what to do..
Apply transdermals daily. Observe. Be smart. Adjust.
Once inflammation is down stretch the tissue(help with heat to soften the tissue for easier stretch) as often as possible in a smart way(ease into everything) without creating any new problems/injury.   
Keep applying transdermals(especially ascorbic acid/Vitamin C). Takes many weeks/months. I've written in detail how to do it.
I think I have not much to add. If you learned something and gotten better thanks to my advice, help other people too!
I have a stronger better, bigger penis than before. Got basically rid of the rest of my plaques now. Can't feel them anymore. 3 months of daily stretching/VED and up to hourly DMSO+X application. My mission is done here. Will answer to PM's if I can.
Title: Re: DMSO+X Revisited 2019
Post by: Tom_E on January 28, 2020, 12:49:52 AM
Thanks Melting!
I agree that getting to the plaque itself is something we need to try to do.  Oral medications are good but affect the whole body as well.  Sometimes in a good way and sometimes not, but I really want to learn how to get to the plaque using DMSO, so I will read up and all you and the others said here.

Mainly trying to find the right effective mix that holds together well, and contains the right things that can help soften the plaque so I can stretch it out more AND\OR help to break up\reduce the plaque.
So far I have seen the most basic and cheap mix would be: Just some DMSO, Water and Ascorbic Acid(Vit C) will soften your plaque for $3.50 or so.
I take it that would be too runny so have to mix other things to hold it together eh.
Then add more things ... I have some reading to do.

Melting, in your opinion, what is an effective DMSO mix, holds together without running, that gets into the plaque and softens\breaks it up\reduces it?

Thanks Melting and all who posted ideas for DMSO mixes here.
Peace and Respect to you all.
Tom
Title: Re: DMSO+X Revisited 2019
Post by: Agaig on January 29, 2020, 03:14:05 AM
Thanks for the post. It gives much hope and confidence. I have been practicing traction with castor oil and hot shower. Now I am gonna try your protocol. But  I just want to make sure that HEAT doesn't affect my sperm production.
Title: Re: DMSO+X Revisited 2019
Post by: diehardpatriot on January 30, 2020, 01:24:57 PM
I want to try this but I also don't want to do all the work ... does anyone in the US make this and is willing to sell it?
Title: Re: DMSO+X Revisited 2019
Post by: diehardpatriot on January 30, 2020, 01:35:29 PM
Please keep us updated. This is very interesting. Let us know all the perks. (effects on pain, inflammation, curvature, flaccid hang) leave no details!
Title: Re: DMSO+X Revisited 2019
Post by: melting on February 02, 2020, 02:53:30 PM
Tom_E
Quote from: Tom_E on January 28, 2020, 12:49:52 AM
Thanks Melting!
So far I have seen the most basic and cheap mix would be: Just some DMSO, Water and Ascorbic Acid(Vit C) will soften your plaque for $3.50 or so.
I take it that would be too runny so have to mix other things to hold it together eh.
Then add more things ... I have some reading to do.
Yes, most basic and very cheap(I buy 10€ DMSO on amazon germany)mix. Easy to mix and harmless if done smart.(no plastic and poison nearby). It being "runny" just means you have to hold your penis horizontal, for some minutes, so it stays where you want it. You can add some drops of healthy oil, e.g castor oil, and shake it like crazy before application to get a temporary mix.
Adding emulsifiers is just making the application easier to apply(I paint penis with it and walk around, brush teeth or sit on a clean white towel) but makes production more complicated.
Still I create a mix in 5 minutes with household items in my kitchen WHILE being aware to not put DMSO in combination with harmful plastics and other stuff it reacts with and I don't want in my body.
Quote from: Tom_E on January 28, 2020, 12:49:52 AM
Melting, in your opinion, what is an effective DMSO mix, holds together without running, that gets into the plaque and softens\breaks it up\reduces it?
I described on the last 2 pages. I don't have the means to make exact measurements of the ingredients. Every batch I make is a bit different. I add a bit of emulsifiers as explained and if it's not thick enough I add some more..
I have no worries cause all ingredients, explained in this thread, are harmless, imo. If someone still does mix DMSO with something harmful after I mentioned it 100 times and all the dangers are explained here and on page 1 of google it's their own damn fault ;)



Agaig
Quote from: Agaig on January 29, 2020, 03:14:05 AM
I have been practicing traction with castor oil and hot shower. Now I am gonna try your protocol. But  I just want to make sure that HEAT doesn't affect my sperm production.
Heat can only affect sperm production temporarily and if done for a long time. Don't worry about hot water.(dont burn OBVIOUSLY) Traction with heat good. castor oil good but if plaque deep in penis won't get there without DMSO.



diehardpatriot (AMERICA IS THE BEST! EU style of government SUCKS!)

Quote from: diehardpatriot on January 30, 2020, 01:24:57 PM
I want to try this but I also don't want to do all the work ... does anyone in the US make this and is willing to sell it?
lol. There were 2-3 guys(idk who) in the US who had pharmacies make DMSO mixtures. You can ask around..
Sending DIY DMSO mixes around could be problematic but Idk.

Quote from: diehardpatriot on January 30, 2020, 01:35:29 PM
Let us know all the perks. (effects on pain, inflammation, curvature, flaccid hang) leave no details!
I already did for the most part in this thread and through my posts. DMSO is a very known substance which you can find a lot about on google. In regards to the penis a lot is found here and other mens forums and some penis enlargement forums toyed with it..

In any case it would be great if someone who has the means to create highly controlled DMSO+X substances would do that(pharmacologists, chemists step up!). I'm sure some American will do it sooner or later if the theme is kept up.
Title: Re: DMSO+X Revisited 2019
Post by: Tom_E on February 02, 2020, 11:43:21 PM
Thanks Melting.  I appreciate the details you gave and yes you are correct, you put a lot of details in the thread already and thanks for that.  Kudos to your for giving back to us what you have learned.  I have tried various things over the last couple months and at this point the next logical step is to somehow get to and into the plaque. Sometimes I feel panic and just want an answer right away hehe.  So I took a deep breath and read the entire thread and other threads on the subject and you provided a lot of good stuff here my friend!  I will try different preparations of the DMSO+ Mix and write down detail procedures as well as I like to follow step by step instructions, especially when I feel stressed. 

The first few days I will make sure the DMSO is not heavily prominent in the mix and then in following days will increase its amount, of course never using 100% DMSO, and to always put some castor oil on during or right after.

Here is my first rough draft of step by step instructions for using DMSO+Mix:

-----------------------------------------
DMSO can carry a lot of chemicals right through the skin so cleanliness is a top priority.
Take BEFORE measurements of plaque size\feel as well as all the usuall Penis measurements.

METHOD DAY 1:
Early in the day:
Clean a glass container with clean water.
Clean your penis with clean water.

In a clean class container:
Mix 1 tablespoon of distilled water, 2 tablespoons pure DMSO.
Add pure ascorbic acid powder until it turns into a thin paste.
Put penis on flat level surface.
Rub mixture on the skin where you feel the plaque.
Leave on for 15 min.
Rinse with clean water.
Apply 1 tablespoon of castor oil to same skin area.
Put on clean underwear.

Later in the day: (perhaps a couple hours later or when you have time)
Repeat above procedure.

METHOD DAY 2:
If no bad reaction from yesterday, then early in the day:
Clean a glass container with clean water.
Clean your penis with clean water.

In a clean class container:
Mix 0.5 tablespoon distilled water, 2 tablespoons pure DMSO
Add pure ascorbic acid powder until it turns into a thin paste.
Put penis on flat level surface.
Rub mixture on the skin where you feel the plaque.
Leave on for 20 min.
Rinse with clean water.
Apply 1 tablespoon of castor oil to same skin area.
Put on clean underwear.

Later in the day: (perhaps a couple hours later or when you have time)
Repeat above procedure.

METHOD DAY 3:
If no bad reaction from yesterday, then early in the day:
Clean a glass container with clean water.
Clean your penis with clean water.

In a clean class container:
Add 2 tablespoons of pure DMSO.
Add pure ascorbic acid powder until it turns into a thin paste.
Put penis on flat level surface.
Rub mixture on the skin where you feel the plaque.
Leave on for 20 min.
Rinse with clean water.
Apply 1 tablespoon of castor oil to same skin area.
Put on clean underwear.

Later in the day: (perhaps a couple hours later or when you have time)
Repeat above procedure.

METHOD DAY 4:
If no bad reaction from yesterday, then early in the day:
Clean a glass container with clean water.
Clean your penis with clean water.

In a clean class container:
Add 2 tablespoons of pure DMSO.
Add pure ascorbic acid powder until it turns into a thin paste.
Put penis on flat level surface.
Rub mixture on the skin where you feel the plaque.
Leave on for 20 min.
Rinse with clean water.
Apply 1 tablespoon of castor oil to same skin area.
Put on clean underwear.

Repeat this procedure 2 more times during the day.


METHOD DAY 5:
If no bad reaction from yesterday, then early in the day:
Clean a glass container with clean water.
Clean your penis with clean water.

In a clean class container:
Add 2 tablespoons of pure DMSO.
Add pure ascorbic acid powder until it turns into a thin paste.
Put penis on flat level surface.
Rub mixture on the skin where you feel the plaque.
Leave on for 20 min.
Rinse with clean water.
Apply 1 tablespoon of castor oil to same skin area.
Put on clean underwear.

Repeat this procedure 3 more times during the day.

METHOD DAY 6:
Take AFTER measurements of plaque size\feel as well as all the usuall Penis measurements.
--------------------------------------------

Please comment and let me know how you feel about this procedure if you feel I should change something.
What I am unsure of is how long do I leave the DMSO+Mix on the skin?

The procedure I put above slowly adds more DMSO and less water to the mix until there is only pure DMSO and pure ascorbic acid powder.
Please let me know if any of you feel this would be too strong a mix?  I think the ascorbic acid powder will dilute the DMSO just fine but I will make note of how my skin looks and feels later.

Please note that the skin may get irritated and may peel off a bit.  Then you may need a less heavy DMSO mix or leave on the caster oil longer or to take a break for awhile...etc.

Any input is welcomed! :)

I will try this method starting tomorrow and then post my results now and then to let you know how it is all going.
Cheers fellow warriors!

Title: Re: DMSO+X Revisited 2019
Post by: melting on February 03, 2020, 02:20:56 PM
Quotea deep breath and read the entire thread
lol. It's a lot and sometimes I write too much. That's one thing that could be done better in a new thread by me or someone like you to break it down more clear and more straight point by point. It's really easy once the basics are understood and one has prepared and applied a mix for 2-3 weeks. I'm glad for some feedback to maybe perfect the presentation.

Quote from: Tom_E on February 02, 2020, 11:43:21 PM
The first few days I will make sure the DMSO is not heavily prominent in the mix and then in following days will increase its amount, of course never using 100% DMSO, and to always put some castor oil on during or right after.
This is VERY smart! You can start with even more dilution and slower progression than you laid out below.

Quote
Mix 1 tablespoon of distilled water, 2 tablespoons pure DMSO.
Add pure ascorbic acid powder until it turns into a thin paste.
Wait until the heat reaction of water and DMSO is gone(~5minutes).(I fear the heat reaction could destroy vitamin C if added same moment). Don't use metals or plastics to mix DMSO. Clean Wood, glass or ceramic is ok.
1.I mix first water with DMSO(heat reaction). (in 1 glass)
2.Then I mix ascorbic acid with water. (in another glass)
3.Then I mix both together. (Sometimes I then add some more ascorbic acid to fully saturate the mix.)
So if you have an existing batch/mix, You add 3. to the existing batch.
Quote
Rub mixture on the (penis) skin
Try it on your hands first. If it burns add a lotion/castor oil and dilute concentration on skin with that, and not water.
QuoteRinse with clean water.
You can do that if there was no burning feeling at all. You can also instead rub in what remained with a bit castor oil.(oil is sticky and ascorbic acid can discolor, so don't wear expensive underwear).
QuoteLeave on for 20 min.
Ok but the DMSO will be gone within 5-15 minutes and anything that sits still on the skin is probably not going very deep.
I just apply lotion/oil over it to rub the remains into the skin and then go about my day. If I have time I apply a mix, put thin oil over it, then 15 minutes later I put a new DMSO mix on the skin and again thin oil/lotion over it, repeat. I basically made sure the penis is flooded with the ingredients. Of course don't do that right away, only after some days/weeks. Did that often with no harm at all, (especially the new mixes with the emulsifiers).
Quote
METHOD DAY 3:
Add 2 tablespoons of pure DMSO.
Add pure ascorbic acid powder until it turns into a thin paste
Ok you add that to mix you did the prior day? Then OK.
Always add some water to the dmso before adding the ascorbic acid. Could be 1 part water 9 parts DMSO.

Quote
What I am unsure of is how long do I leave the DMSO+Mix on the skin?
The procedure I put above slowly adds more DMSO and less water to the mix until there is only pure DMSO and pure ascorbic acid powder.
Please let me know if any of you feel this would be too strong a mix?
Ok I think I answered that above. No pure DMSO cause DMSO will always react with water and skin is full of water. So it needs to always be diluted with water. At least 5 parts water to 95 parts DMSO.

Always be careful. But consider this: Race horses who are worth millions more than we ;)lol, are rubbed/splashed with DMSO in barn's since decades. The highest risk are chemicals like cleaning materials or harmful plastics etc.

QuoteTake AFTER measurements of plaque size\feel as well as all the usuall Penis measurements.
I noticed an impact on the feel often within days. Application as often as possible is the key. At least 1-2 times daily. Imagine(!) throwing the plaque into a bottle of DMSO+Ascorbic acid 24/7,..
Note that my personal biggest progression, I made in combining this treatment with traction and VED. Note that one should be careful/refrain with traction and VED if you are in pain or in acute inflammation.(in that case bring that down first until carefully introducing traction/VED).
Also don't stop any other oral treatments/medications. Especially with VitaminC/ascorbic-acid there's not much danger at all for any over dosage or contraindications.

Any more questions I happily answer.
Title: Re: DMSO+X Revisited 2019
Post by: Tom_E on February 03, 2020, 10:12:11 PM
Oh OK I see. Hey thanks Melting! for your input and helping me tweak the formula\method some more.  It's great to have a Forum like this to share thoughts and help each other come up with new ways to treat this situation.  Ok I'm off to mix me up some DMSO+Mix Version 1!
I'll post how it goes throughout the week. 

Cheers!
Title: Re: DMSO+X Revisited 2019
Post by: aquintance22 on February 21, 2020, 03:20:20 AM
What do you think aboug Lugol's solution (iodine) mixed with DMSO?

1 drop = 1.0000mcg

https://www.drlowe.com/thyroidscience/cases/Derry.Iodine.Regen.6.7.08.pdf
Title: Re: DMSO+X Revisited 2019
Post by: Boar on February 28, 2020, 12:50:47 AM
I made this account so I could make this post.
In order to fix peyroine we must eliminate inflamation and fibrin in early stages and reverse calification in later stages. We should have a post about "x"s, their benefits, studies and ranked.
Note: Chronic(late) mixers will mostly all help in early phases since they remove the progression of the scar, calcium and plaque.

Acute(early) Phase
Goals: Lower inflammation, reduce pain, soften and remodel tissue

1.Verapil Tropical: Proven and Medically Used to prevent calcium deposits, scar and fibrin deposits.

2.Caster oil: Evidence and used as Caster oil packs to lower inflammation, softens tissue and reduces pain
https://exercisesforinjuries.com/castor-oil-inflammation-myth/

3.Emu oil: Proven to reduce inflamation, possibly reduces pain, possibly softens tissue.( need more info on emu oil vs caster oil)
https://healthyfocus.org/emu-oil-benefits/

4.Potaba:(Paba): Prevents scar formation and reduces fibriods. I placed it in acute because study did not specifiy how long the patients had peyronie for.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857830/

5.Geranium oil: Reduces inflammation
https://journal-inflammation.biomedcentral.com/articles/10.1186/1476-9255-2-1

6.Alo vera:Known to reduce pain and improve healing(provide a link im tired)

7.Methyl salicylate: Prevents inflammation
"However, in the body it metabolizes into salicylates, including salicylic acid, a known NSAID
Nonsteroidal anti-inflammatory drugs (NSAIDs)"

8.Boron: Might prevent scar formation
https://link.springer.com/article/10.1385/BTER:85:1:23

9.Vitamin E: Frankly USELESS, studies where some inflammation is REDUCED have done so with ORAL Vitamin E. Studies on scars post trauma with TROPICAL Vitamin E show no improvement. Some show slightly worse healing and this has also mentioned in another artical. Forgot to mention that the only use Vitamin E could have is clearing out free radicals after we have found another mix to consistently remove calcification.
https://www.the-dermatologist.com/article/8065

https://www.ncbi.nlm.nih.gov/pubmed/10417589/

10. Hydrocortisone?: Cream used to reduce inflammation and allergic reactions. Not sure if its safe to use since I was told it thins the skin. Feedback Appreciated

Chronic to stable phase:
Goals: Reverse/prevent calification, soften tissue, reduce scar tissue

1.Magnisium (MgSO4/Epsom Salts or
Magnesium chloride): Proven to reduce and prevent calification, and soften tissue.
https://www.ncbi.nlm.nih.gov/pubmed/2133625

https://drsircus.com/magnesium/calcification-and-its-treatment-with-magnesium-and-sodium-thiosulfate/

2.Vitamin C(Acsorbic Acid): The user "melting" has talked extensively on this. Prevents Scar tissue formation, Softens tissue, Possibly reverses calification.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673383/

3.Vitamin K(k2): Possibly reverses Calification
https://www.nutraingredients.com/Article/2017/06/23/Vitamin-K2-may-reverse-calcification-of-blood-vessels-in-people-with-kidney-disease

4.Iodine(Mainly "Lugol's Iodine"/SSKI):Promotes correct healing, very slowly reduces scar tissue( when applied twice a day for about a year directly on/into scar) Possibly Anti-Inflammatory.
https://www.icnr.com/articles/wondersofiodine.html/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754371/

5.Natriumthiosulfat Na2S2O3 pharmaceutic:
Reverses calification as the user "melting" pointed out.
Quote
"Furthermore, the enhanced aqueous solubility of calcium thiosulfate allows for successful mobilization and clearance of the vascular and soft tissue calcium deposits"
Link from the user "melting": https://cjasn.asnjournals.org/content/1/6/1161

6.EDTA Chelation: WARNING THIS HAS NEVER BEEN DONE BEFORE AND IS PURE SPECULATION. I found out about EDTA being a possible solution when I clicked a link and it brought me to a gu trying to sell a book on peyronie having it as a possible treatment. EDTA supposely sticks to metals and like calcium and removes them from the body. It has been used in plaque arteries and on eyes with calcium deposits.
https://www.mayoclinic.org/diseases-conditions/heart-disease/expert-answers/chelation-therapy/faq-20157449

https://www.nature.com/articles/eye2017264
Book I mentioned: https://peyroniesdiseasehelp.com/

Feedback wanted:That took forever well good luck experimenting and pls give me links. Also curious about that hydrocortisone one and a link for alo vera

Side note: Going to see an urologist soon and ask for pentox, cialis, and verapil shorts or verapil ionthesis or verapil/pentox/dmso cream made in a compound pharmacy. Got the idea from that old post. Am I fogetting anything or is there anyting else I should ask? :)
Title: Re: DMSO+X Revisited 2019
Post by: melting on February 28, 2020, 07:05:28 AM
Quote from: Boar on February 28, 2020, 12:50:47 AM
I made this account so I could make this post.
In order to fix peyroine we must eliminate inflamation and fibrin in early stages and reverse calification in later stages. We should have a post about "x"s, their benefits, studies and ranked.

You got it! Thanks for this great addition to this thread! Everyone reading, please share if you have anything to add. Also inform others if you saw results outside of this thread.

Quote9.Vitamin E: Frankly USELESS, studies where some inflammation is REDUCED have done so with ORAL Vitamin E. Studies on scars post trauma with TROPICAL Vitamin E show no improvement. Some show slightly worse healing and this has also mentioned in another artical.
https://www.the-dermatologist.com/article/8065
https://www.ncbi.nlm.nih.gov/pubmed/10417589/

A lot of inconclusive stuff.. true..The sole use of V-E to combat Peyronies Disease is a water drop on a hot stone..
That said it can work together with vitamin C and other supplements,.. there are some combination effects. I often add some drops of vitamin E into DMSO+X+X solutions. Don't see it hurting.

Quote10. Hydrocortisone?: Cream used to reduce inflammation and allergic reactions. Not sure if its safe to use since I was told it thins the skin. Feedback Appreciated

Yeah there's often problems with regular use. But I can see using in a protocol from time to time..
As said often.. cycling through several supplements daily/weekly/monthly might make sense..



Quote5.Natriumthiosulfat Na2S2O3 pharmaceutic:
Reverses calification as the user "melting" pointed out.
Quote
"Furthermore, the enhanced aqueous solubility of calcium thiosulfate allows for successful mobilization and clearance of the vascular and soft tissue calcium deposits"

Would like a link from melting, not sure if this has been done
For example here:
https://cjasn.asnjournals.org/content/1/6/1161
There are several more references when you search google for the words.


Quote6.EDTA Chelation: WARNING THIS HAS NEVER BEEN DONE BEFORE AND IS PURE SPECULATION. I found out about EDTA being a possible solution when I clicked a link and it brought me to a gu trying to sell a book on peyronie having it as a possible treatment. EDTA supposely sticks to metals and like calcium and removes them from the body. It has been used in plaque arteries and on eyes with calcium deposits.
https://www.mayoclinic.org/diseases-conditions/heart-disease/expert-answers/chelation-therapy/faq-20157449
https://www.nature.com/articles/eye2017264
Book I mentioned: https://peyroniesdiseasehelp.com/
Good idea! EDTA..
The guy who wrote the book did his homework. Basically a lot what you can find for free here.. but probably missing a lot too.

Quote
Feedback wanted:That took forever well good luck experimenting and pls give me links. Also curious about that hydrocortisone one and a link for alo vera

Well, good work and thx for keeping the thread alive.
The DIY nature of all of this will prevent a lot of people from doing it, sadly. 

You distinction between active and settled phase is good. But consider that a lot of the settled phase supplements could be very effective during active phase too. I would use Vitamin C in active phase also. Just put more emphasis on the active phase supplements in active phase and a bit less in settled phase and vice versa.

Aloe is just overall a good supplement which combines nicely with other supplements. If you have a sunburn or any other skin inflammation and add aloe you will notice it's great effects immediately.

Quote
Side note: Going to see an urologist soon and ask for pentox, cialis, and verapil shorts or verapil ionthesis or verapil/pentox/dmso cream made in a compound pharmacy.

Great idea! Just using DMSO+X alone is not enough. Need to be healthy, good food, oral supplements and stretching/expanding the tissue with extenders, VED and manual exercise..(as described on the forum)


Title: Re: DMSO+X Revisited 2019
Post by: melting on February 28, 2020, 07:10:06 AM
Quote from: aquintance22 on February 21, 2020, 03:20:20 AM
What do you think aboug Lugol's solution (iodine) mixed with DMSO?

1 drop = 1.0000mcg

https://www.drlowe.com/thyroidscience/cases/Derry.Iodine.Regen.6.7.08.pdf
Yes, possible. Iodine, lugols,.. nascent iodine.. always try on arm first.
Title: Re: DMSO+X Revisited 2019
Post by: Boar on March 04, 2020, 03:15:25 AM
Someone made another post about this but its something ive thought about. How about combining dmso with commonly used scar gels. Like Silicone Gel, Allantoin, and others.
Title: Re: DMSO+X Revisited 2019
Post by: melting on March 04, 2020, 09:17:33 AM
Quote from: Boar on March 04, 2020, 03:15:25 AM
How about combining dmso with commonly used scar gels.
Great idea. One has to identify the ingredients and then check what their molecular weight is.
Most of these scar gels work on superficial scars. DMSO possibly could transport ingredients deeper.

Silicone Gel is, as I understand, basically forms of silica which has a low molecular weight of 60.08 g/mol

QuoteSilicon is present everywhere in the body. In bones, cartilage, hair, blood vessels, skin, teeth, tendons, nails. Silicon is abundant in babies when they are just born. When we are born our body has a large supply of silicon and low calcium. Generally the body is full of youth when there is more silicon in relation to calcium present. Many studies have shown that the ratio of silicon to calcium is a biological indicator of youth.
Very interesting. Peyronies fibroids are often having a lot of calcium to patch up an injury. I guess it's possible that if silica was instead available/used we could have better flexibility in the injured/inflammed area than with the "hard" calcium deposits. 

Quote
Silica is an essential element in collagen synthesis. A deficiency could significantly inhibit collagen production, resulting in a loss of elasticity and flexibility in the body's cells and increasing the likelihood of fine lines and wrinkles, as well as brittle hair and nails and joint-related problems

Sounds like a truly great addition to any DMSO+X protocol.
Quote
Silica also creates bonds between the protein molecule that are responsible for the skin's natural ability to retain water, which is critical for repair and cell renewal
One can imagine this is missing from peyronies plaques which are very dense and rather "lifeless".

QuoteSilica is only slightly soluble in water.
BIG PROBLEM! Apparently it has to react with something else first.
https://www.quora.com/Which-solvent-can-dissolve-silica-or-SiO%E2%82%82
This also obviously(!), like always, means any mix with DMSO + Silica has to be first tested how it reacts with skin.
This is surely worth researching deeper on how one could mix Silica with DMSO. Maybe DMSO just mixed with an already existing gel. 
If someone does, please report here.
Title: Re: DMSO+X Revisited 2019
Post by: Sharjy on March 10, 2020, 11:50:19 AM
Hey all,

Just signed up to the site after browsing for a while.

The DMSO mixture could be mixed with nigella sativa oil as it shows anti-fibrotic and anti-inflammatory effects.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987441/ (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987441/)

I will be trying a mixture of DMSO (70% w/ 30% aloe vera), nigella sativa oil (black seed oil - approx 6.9% thymoquinone - its also a carrier oil which will help penetrate the skin layers), pomegranate oil (anti-inflammatory) pumpkin seed oil (aids fibrosis) and ajwa date seed powder (anti-fibrotic)

Green tea and black ginger powder could also be a good combo in the mixture (natural PDE5i')

Hope this also helps my hard flaccid and the reductions of size in my glans :).
Title: Re: DMSO+X Revisited 2019
Post by: melting on March 12, 2020, 08:48:39 AM
Quote from: Sharjy on March 10, 2020, 11:50:19 AM
Hey all,
Thanks for the post. Very well presented.
I wouldn't use it all at once in one application. The more you mix in the more interactions and less the DMSO will pull transdermaly. Interactions often increase the molecular weight and it wont go deep.
Try to mix only 1 active substance with DMSO.

There's a suprisingly good amount of research into essential oils and they might be effective with DMSO to go deep into the peyronies sites.
thymoquinone = molecular weight 164,20 g/mol
Very good!
Title: Re: DMSO+X Revisited 2019
Post by: diehardpatriot on March 26, 2020, 01:15:10 PM
Has anyone came up with a solid solution?? When you guys do please post it. I know everyone's just experimenting right now.
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on March 26, 2020, 03:41:51 PM
DMSO is pretty much just doing what one believes may work for them.  Only evidence so far is a guy or two on here who report improvements in wasting/narrowing of penis.
Title: Re: DMSO+X Revisited 2019
Post by: melting on March 27, 2020, 07:13:20 PM
Oh Tony again at it trying to dismiss the success of other people. 
You're a bitter person. 
Still promoting people in active stage/inflammed to use VED and traction? DANGEROUS!
 
Tony's mission is to make everyone get their dicks chopped up and wear implants like him. Sick person.   


Title: Re: DMSO+X Revisited 2019
Post by: TonySa on March 27, 2020, 09:09:41 PM
Oh my gosh, total projection (look it up)!
Title: Re: DMSO+X Revisited 2019
Post by: Fix This on March 29, 2020, 07:26:14 AM
Hi

I've just come across this thread . I've been using DMSO for a while with a mixture of Castor Oil, Emu Oil, Coconut Oil, Ibuprofen, PABA and ALC. I don't do it every day, on and off really . Have also been doing traction and VED on and off for about a year now ( skin inflammation and a blister have made me have to take breaks with this)

Anyway,  ultimately I still have the same curvature as a year ago (30-40 degrees estimate ) although hourglassing has improved

Melting - have you actually had any improvement in curvature with your mixtures ? And if so, can you tell me which mixture exactly please? There seem to be quite a few different variations on here

Many thanks

Fix
Title: Re: DMSO+X Revisited 2019
Post by: FUNKOPS on April 02, 2020, 09:53:03 AM
My peyronie's started 5 years ago. My issue was losing size really. No bends or pain. I went from a little over 7in thick to 3in with over half girth gone in like 6 months. Of course I was in a panic since I still have a very healthy sex life. I saw urologist  and was basically told you have peyroines and really nothing we can do. He gave me a Rx for pentox which I took for 6 months with no real help. I thought about surgery, but after I heard the horror stores I decided to look elsewhere. At first I was scared to try DSMO + ? treatments, but it got to the point I ran out of options. I have been doing a treatment that has worked for me for a little over a year. Now it's nothing amazing, but I got penis back to a little over 6ins and a little over half girth back. My plaque was just the head and just before base. They use to be pea size, but now can barely feel anything. Sometimes I feel nothing, but has to be something since its not back 100%. I will give you the treatment I use and it may work for you. It's not very expensive and most supplies last 6months. Here is what I do.

DMSO ROLL-ON 70% - can get 2 bottles from amazon for 13 bucks and 2 bottles last a year.
Cold Pressed castor oil - get local for 12 bucks and last 6-7 month.
Cold pressed small bottle of Jojoba oil- paid 10 bucks for a bottle.
Citrulline malate 2:1 - I use hardrhino which is 22 bucks for 5 month supply.


Morning- 1. Take hot shower letting water flow on penis 5 mins before getting out.
              2. Dry penis off very well and roll on DSMO over entire penis not just plaque areas.
                  Let it set for a minute.
              3. Next apply dime size spot of castor oil and 2 drops of jojoba oil to penis and massage entire
                  penis for 3 mins.
              4. Then put on cotton underwear.
              5. Take 1 serving of Citrulline malate 2:1 with breakfast.

Night - repeat above treatment.


This is what I have been doing and its gotten better with no more plaque spots, so it hasn't gotten worse. Low cost treatment that has worked for me and it may work for others. Sex life is better since I started...not where it was, but way better than it was. Hope this helps. Good luck in whatever you do.
Title: Re: DMSO+X Revisited 2019
Post by: Mr man on April 08, 2020, 05:02:43 PM
That's Bloody brilliant mate. I'v ordered my jajoba oil already. Just one question. What's the Acetyl-L-Carnitine for?
Title: Re: DMSO+X Revisited 2019
Post by: Indented on April 10, 2020, 10:26:58 AM
Melting or anyone else.

I had quit using dmso and vitamin c (I will try again here shortly) because my breathe smelled so horrible.

The dmso I have is a 99% pure bottle that was a little pricey for what it was. I followed the directions as laid out here. I originally had the 70:30 blend from amazon but saw little result from the 70:30 mixture of dmso. Does anyone else have a bad smell or breathe issue when using pure

So far the restorex and ved have helped. (Never mind the restored gave me hourglassing all around the clamp site. )
Title: Re: DMSO+X Revisited 2019
Post by: samsung on April 10, 2020, 11:36:40 AM
It gave you hourglassing at the clamp site, but it helped? Those seem to be contradictory statements.
Title: Re: DMSO+X Revisited 2019
Post by: projectpd on April 13, 2020, 02:28:44 PM
great post @Boar; re hydrocortisone ,I remember this report -https://academic.oup.com/ptj/article-abstract/62/7/995/2727448?redirectedFrom=fulltext
I read dexamethasone is 40-50 times more potent and longer acting, and is also amenable to iontophoresis.  I did get some hydrocortisone cream and added a few times with DMSO without noticing any issues on the skin, but never tried the iontophoresis: They work as an anti inflammatory, so may be useful in the acute phase only.  I wish I'd tried it in the acute phase .
Title: Re: DMSO+X Revisited 2019
Post by: Indented on April 13, 2020, 02:40:08 PM
Samsung, restorex helped in restoring length and girth as I had lost over an inch. After 6 months of usage as per instruction I noticed the dull ache and have since ceased using restorex as the entire area around the head (in a circle) has hourglassing, when I first started down this path I did not have it. My uro (who was recommended from this website) also believes the restorex caused my hourglassing.
Title: Re: DMSO+X Revisited 2019
Post by: projectpd on April 13, 2020, 04:46:26 PM
I don't own one or have seen one but it looks as if it uses a compressing clamp for retention, unlike phallosan or penimaster, which avoid compression for their retention mechanism. I wonder if you could use one of those two's retention mechanisms with the restorex, or improvising an added fulcrum for those models to emulate restorex might not be be too difficult?
Title: Re: DMSO+X Revisited 2019
Post by: MacMathuna on April 13, 2020, 06:58:40 PM
Funkops,

So, do you not rinse the mixture off of your penis?

Also, what's the jojaba oil for.

Thanks for the work you're doing.
Title: Re: DMSO+X Revisited 2019
Post by: MacMathuna on April 13, 2020, 07:01:53 PM
Melting,

You're saying DON'T do VED / traction during acute phase. Why?

Also, how do I know if I'm in acute phase??

Is DMSO+ ok in acute phase?
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on April 13, 2020, 07:10:54 PM
Traction and VED are recommended in the acute stage to prevent worsening, don't wait!  If melting read the studies he would know this.
Title: Re: DMSO+X Revisited 2019
Post by: Curlywurly on April 13, 2020, 07:36:41 PM
Quote from: melting on November 13, 2019, 08:14:11 PM
I would add Vitamin C a.k.a Ascorbic Acid to such a solution. Can't do much wrong with Vitamin C and it's very useful for what we try to do..
The only thing that can happen with Vitamin C is that it can stain the skin yellow after some time. But this goes away within days.

Ok, here's an example mix:
(This sounds like a long DIY but after doing it 2-3 times it's a 5 minute thing.)

You need:
-2 Brown glasses with a glass eye dropper(pharmacy) or another cap that isn't made of harmful plastics(https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/Product_Information_Sheet/d2650pis.pdf read - compatibility )
-Ascorbic Acid powder (In germany you can buy it in every big grocery store or pharmacy as pure powder)
-Castor oil(cold pressed! Internet or pharmacy)
-DMSO 99,99% quality (pharmacy or internet)
-A handheld kitchen mixer(or similar) Don't use it with the DMSO to avoid the DMSO dissolving plastic parts.
-An open container where you can mix the non DMSO parts with the mixer.
-Xanthan(Internet or grocery store)
-Lecithin(Internet, pharmacy or grocery store)

What I do with that:

-Clean area, no poison or other harmful substances that DMSO can transport into skin nearby.
-Put 100ml DMSO into the brown glass.
-Add some water(5ml..). Shake lightly. The solution will heat up. Just let it stay until cooled down.

-Mix and saturate 25ml water with ascorbic acid powder in an extra container. Just add the powder until it stops dissolving.
-Add 10 ml Castor oil. The oil and water wont mix!
-Add a small pinch of Xanthan and/or Lecithin to it. Then mix it thoroughly with the mixer. It will combine the oil with water.
The solution gets more solid the more Xanthan and Lecithin you add. Start small and keep adding until you're satisfied. If it gets too solid, add extra water which will make it more fluid.

-Fill the Brown glass that has the DMSO in it with the mixed solution. Shake the glass or mix it with something that doesn't react with the DMSO(I use a wooden Sushi stick). If the mix is too fluid you can add some water+xanthan solution.

Then test a small amount on your arm and wait an hour if there's a bad reaction.(if there's burning then you need more water and/or oil)
You can test and tweak the amounts. I found any solution with more than 90% DMSO will be tough on the skin.
I use a solution for like 2-3 weeks without problems. Beyond that many supplements will degrade.

Apply it as often as possible without having adverse effects(at least once a day) on your skin.
I apply the solution across my whole penis and sometimes focus more on where my plaque sits. Can be massaged in a bit.
Then I let it sit for 5-15 minutes. (like during my morning routine in the bath). I clean off all residue or apply some pure castor oil or natural/bio lotion..

This example mix, you can replace ascorbic acid with other supplements.

What sizes brown bottles with the droppers do you usually use and generally how many ml of a DMSO + X do you make per concoction?
Title: Re: DMSO+X Revisited 2019
Post by: melting on April 23, 2020, 04:35:30 PM
Quote from: Fix This on March 29, 2020, 07:26:14 AM

Melting - have you actually had any improvement in curvature with your mixtures ? And if so, can you tell me which mixture exactly please? There seem to be quite a few different variations on here


I'm fully functioning and basically got rid of my plaques.

I had hourglass and twisting. I never had the typical up/down curve.
I always was very aware of my plaques from start to finish. Mine were deep inside, which I think(!) creates more often the hourglass and the plaques on top of the tunica create the bends. That's how I arrived at DMSO which is known to be able to penetrate deep.

I started years ago with DMSO + Iodine, DMSO+magnesium and "thackers formula"(old recipe talked about on this and other forums).   

I felt small improvements when I applied it for some days. The very hard plaques got softer. But whenever I stopped they got harder again within days/1-2 weeks. That is most probably due to calcification which gets hard and "coats"/isolates the faulty inflamed tissue. 
DMSO + X, especially magnesium and Vitamin C is able to dissolve/chelate calcium. 

It's a kind of crude way to get at the plaque if focused on one application. A lot gets into the bloodstream or misses the plaque. But if done often enough the amount that get's to the plaque starts to matter.
So I started to apply it several times daily for months and noticed the plaques getting slowly smaller staying soft which then enabled straighter/fuller erections.   
At some point I also implemented extending and VED. I figured stretching the soft plaques and potentially allowing blood circulation getting to them will help. 
I used the extender for 4-16 hours everyday after applying DMSO+X and ended the day with VED.

After 6+ months daily, several times application, I got the point where I had a functioning erection again but still palpable plaques. Big hassle to mix and apply so I stopped doing it. I continued to use VED and traction from time to time to increase the size and fitness of my penis.

Last year I decided to get rid of the remaining parts and had the idea to do it more practicable, as laid out in in the 1st posts here.


Quote
Hi

I've just come across this thread . I've been using DMSO for a while with a mixture of Castor Oil, Emu Oil, Coconut Oil, Ibuprofen, PABA and ALC. I don't do it every day, on and off really . Have also been doing traction and VED on and off for about a year now ( skin inflammation and a blister have made me have to take breaks with this)

Anyway,  ultimately I still have the same curvature as a year ago (30-40 degrees estimate ) although hourglassing has improved


I always was wary of using all supplements in one mix. There might be interactions and I'm not sure if the DMSO is able to pull in all of the ingredients. 
So what I do is to use 1 supplement with DMSO + Oil + Emulgator/thickener. I detailed a lot in this thread.
Sometimes I had 5-10 vials with DMSO + X cycling through them from application to application.
I often had 10+ applications a day. I recommend at least 1-3 a day.

If these are the reasons why you didn't have big success yet I don't know but I assume so. Of course the detractors and critics will argue "you didn't do it right/not enough" is an attempt to put blame on the user to protect the "useless snake oil".. (I have nothing to sell our gain though.. lol) Who knows.. maybe if you did nothing you were worse by now.

I can only tell what I did and hope people find a way that works and report/discuss why.

I would recommend you apply 1-4 DMSO+X mix's directly where you think the "fulcrum/hinge point" is that creates your bend.(probably right in the "middle" of the bend). Doing that as often as possible while stretching "against" the bend as often as possible (IF you are not inflamed and avoiding any further inflamation)
Title: Re: DMSO+X Revisited 2019
Post by: melting on April 23, 2020, 04:43:48 PM
Quote from: FUNKOPS on April 02, 2020, 09:53:03 AM

DMSO ROLL-ON 70% - can get 2 bottles from amazon for 13 bucks and 2 bottles last a year.
Cold Pressed castor oil - get local for 12 bucks and last 6-7 month.
Cold pressed small bottle of Jojoba oil- paid 10 bucks for a bottle.
Citrulline malate 2:1 - I use hardrhino which is 22 bucks for 5 month supply.


Morning- 1. Take hot shower letting water flow on penis 5 mins before getting out.
              2. Dry penis off very well and roll on DSMO over entire penis not just plaque areas.
                  Let it set for a minute.
              3. Next apply dime size spot of castor oil and 2 drops of jojoba oil to penis and massage entire
                  penis for 3 mins.
              4. Then put on cotton underwear.
              5. Take 1 serving of Citrulline malate 2:1 with breakfast.

Night - repeat above treatment.


This is what I have been doing and its gotten better with no more plaque spots, so it hasn't gotten worse. Low cost treatment that has worked for me and it may work for others. Sex life is better since I started...not where it was, but way better than it was. Hope this helps. Good luck in whatever you do.

Thanks for your report and great that you had improvements. The key here seems to be the consistency implementing it into your daily routine. 
The DMSO itself has anti inflammatory properties and the oils do have ingredients/parts that can possibly help too. The citrulline helps with circulation and the penis tissue utilizing NO2.

You can think of adding some Vitamin C mix(you could just mix powder with water and then apply the DMSO) from time to time.
Title: Re: DMSO+X Revisited 2019
Post by: melting on April 23, 2020, 04:57:07 PM
Quote from: Indented on April 10, 2020, 10:26:58 AM
The dmso I have is a 99% pure bottle that was a little pricey for what it was. I followed the directions as laid out here. I originally had the 70:30 blend from amazon but saw little result from the 70:30 mixture of dmso. Does anyone else have a bad smell or breathe issue when using pure


It reacts with something in the blood and it's different for people. I sometimes have that but with some people it smells horrible lol. I think it has something to do with it being sulfur, similar to garlic. 
There are reports that rose scented DMSO doesn't do the smelling. It's inconclusive why and how.

Quote from: Indented on April 13, 2020, 02:40:08 PM
After 6 months of usage as per instruction I noticed the dull ache and have since ceased using restorex as the entire area around the head (in a circle) has hourglassing, when I first started down this path I did not have it. My uro (who was recommended from this website) also believes the restorex caused my hourglassing.
That's very possible and the reason why I recommend to be very cautious with traction and VED. Especially if you inflame easily, for some reason, then traction and VED can create new peyronies type problems. It's controlled manipulation of the tissue and the body can be susceptible to reacting to it unfavorably.
I personally would only add anti-inflammatory measures while in the active phase or when being easily inflamed/hurt.
Title: Re: DMSO+X Revisited 2019
Post by: melting on April 23, 2020, 05:41:52 PM
Quote from: MacMathuna on April 13, 2020, 07:01:53 PM
Melting,

You're saying DON'T do VED / traction during acute phase. Why?



Peyronies is most probably created by an injury or other problem that occurs to the penis(like "bad blood"). 
An injury often is accompanied by inflammation which is part of the natural process of the body to heal.
In most places this process isn't a problem. Like your arm or leg. The penis is a bad spot for that cause of the lower blood circulation compared to the former. Especially when the injury is to the low blood flow tunica.   
The inflammation gets "trapped" and isn't "cooled down" as fast as in a high blood flow enviroment. 
The body then fixes it in a crude way. (hard inflexible scar/fibrous tissue which prevents a normal erection)

Now Imagine you have a cut on your arm. It just closed and then you stretch the tissue apart(traction). Or you apply a vacuum to it(VED). That's obviously making things worse. You're not doing much different when you do that to your penis injury. 

Traction and VED is a manipulation of the penis tissue beyond it's natural function. If you do it just a bit too much you can feel the penis getting sore, which is basically a small injury which creates inflammation. This possibly starts again the same process you had with the initial peyronies. Trapped inflammation that gets dealt with wrongly. 

Some people are very healthy, have great blood circulation, no underlying issues and one isolated incident cause peyronies, like a bend hard penis during intercourse(broken). Still it heals with scar tissue and they now have Peyronies Disease. Most tension that traction or a VED can create wont create more Peyronies Disease plaques.

But let's say you have diabetes, high blood pressure or other issues and acquired Peyronies Disease in some way. Any further small trauma to your penis can be very problematic as your blood and healing process isn't up to solving the problem properly.


QuoteAlso, how do I know if I'm in acute phase??

Is DMSO+ ok in acute phase?

For many people if the plaques don't show up on the doppler(urologist) they are not yet calcified and still in the healing acute phase. Also some people report they they feel pain, soreness or "raw". It's similar to how you feel after a too hard muscles training session. Then they probably got inflammation going on. 
That inflamation should "cool down" first before any physical manipulation is done. 
Generally the closer you are to the incident that cause peyronies the higher the chance you are still healing.

IMO, applying DMSO + (anti inflamatory supplement) during the acute phase or when having prolonged inflammatory responses in your penis makes sense. Obviously always observe how you react to it. 

If you do traction or VED always start with lowest intensity and time. ( Start with no more than 5 minutes and increase slowly. The often proposed 30 minutes traction is too much for most starting and also not enough for some who are already conditioned)

Title: Re: DMSO+X Revisited 2019
Post by: melting on April 23, 2020, 05:48:12 PM
Quote from: Curlywurly on April 13, 2020, 07:36:41 PM
What sizes brown bottles with the droppers do you usually use and generally how many ml of a DMSO + X do you make per concoction?

Vitamin C for example degrades within 2 weeks(it gets orange).
I mostly use 100ml glasses.
It really depends on how many concoctions you use and how often. Sometimes I had 10 differnt DMSO+X glasses cycling the supplements. 
For something expensive like Vitamin D3/mk2 I also used 50ml.


Title: Re: DMSO+X Revisited 2019
Post by: melting on April 23, 2020, 05:52:14 PM
Quote from: projectpd on April 13, 2020, 02:28:44 PM
I did get some hydrocortisone cream and added a few times with DMSO without noticing any issues on the skin, but never tried the iontophoresis: They work as an anti inflammatory, so may be useful in the acute phase only.  I wish I'd tried it in the acute phase .
Cortisol: 362,46 g/mol
So a good candidate to use with DMSO.
And yes as a rather powerful anti inflamatory a good idea for the acute phase. 
I too wish I knew what I know now right after noticing the problem in my penis. Would have saved me a lot of time.
Title: Re: DMSO+X Revisited 2019
Post by: D1990m on May 12, 2020, 10:59:51 AM
This is the most confusing thread on this site. Read through all 3 pages and still have no idea what any of this means. So what do I mix with the dmso.
Title: Re: DMSO+X Revisited 2019
Post by: melting on May 12, 2020, 12:02:31 PM
Quote from: D1990m on May 12, 2020, 10:59:51 AM
This is the most confusing thread on this site. Read through all 3 pages and still have no idea what any of this means. So what do I mix with the dmso.

Sorry, lots of brainstorming, posted without editorializing in this thread ;)

As written in the first post it's a continuation of prior posts -> https://www.peyroniesforum.net/index.php/topic,39.msg334.html#msg334 (10+ page, 15 year old thread)
I might have to write a 2020 thread which is much clearer cause at this point I understand only few will be able to read everything from years back and asking for that is unreasonable.

I think the basics are not that complicated and let me try to get to the point..

Generally:
We use a transdermal agent -> DMSO.   
The transdermal agent is able to transport molecules through the skin deeper than the first layer.

We dilute the DMSO with water cause a pure 100% dmso solution can burn the skin.

Then we combine the DMSO with a molecule/supplement that is said to help with the peyronies plaque. I listed several ones that are able to be combined with DMSO throughout this thread.

For example we combine DMSO with Ascorbic Acid(vitamin C) or iodine or magnesium.

We apply the mix to the penis to bring the supplement right to the site of the peyronies plaque.
Doing that often enough has a positive impact on the plaque(at least for me).

The process of applying was rather cumbersome prior. That's what I tried to solve here and think I did for the most part.
Instead of a runny watery messy oily formula it's now easy to apply like a lotion.   

But the way to create the solution is a bit more complicated than before. 2-3 steps more. The old ways I can repeat too.
As it is all DIY you sure need to understand what you do and why ;) So good that you ask.

Still something unclear? Please ask(!) and I will do my best to make it clearer. 
I'm no doctor or chemist and a non native english speaker, so it's often hard to keep the wording consistent or professional, so please bear with me.

The post about 'the practical how', in detail, is this one(exemplary done with DMSO+Vitamin C):
https://www.peyroniesforum.net/index.php/topic,12587.msg116307.html#msg116307
Please ask a specific question to anything unclear there too if you like.
Title: Re: DMSO+X Revisited 2019
Post by: D1990m on May 12, 2020, 01:43:48 PM
Thanks Melting! Definitely cleared it up. Are these forumlas strictly for plaque? I have soft scar tissue and I'm debating what to use. There is a loss of girth but the curve is very minimal. It feels like it's the Acute stage.
Title: Re: DMSO+X Revisited 2019
Post by: melting on May 12, 2020, 03:39:50 PM
Quote from: D1990m on May 12, 2020, 01:43:48 PM
Are these forumlas strictly for plaque? I have soft scar tissue and I'm debating what to use. There is a loss of girth but the curve is very minimal. It feels like it's the Acute stage.

No, but it's hard to give definite statements on which +X supplement works in which phase best.
Obviously every supplement you combine with DMSO has a different effect.
Calcification antagonists make sense when you have hard(calcified)plaques. But they could also help with preventing soft plaques turning hard.
Anti-inflammatory supplements make sense when you have a "fresh" injury or feel pain or sore but could help all the way.

I mostly used through all stages always in an extra container(not all mixed in one) dmso +magnesium, +ascorbic acid and +ACV(the original Thackers formula). Most times combined with Castor oil. 
 
I softened the plaques and kept using these. When I stopped some days or 2 weeks the plaques hardened again. Using them daily combined with extending and VED made me ~95% functional again. The progress in getting the plaques smaller was slow and gradual but noticeable after weeks and months of daily application.

At times I used up to 10 formulas at once cycling through them from application to application. Sometimes up to hourly applications some days.(at least 1-3 times a day I recommend).
Months ago I added a lot of the supplements I talked on this thread about(easy to identify most times) and felt like with the easy to apply method herein I got rid of the remaining ones faster than the first time. I can't palpate anything anymore and have the best Erection Quality since forever. For some reason Natriumthiosulfat felt especially good this time (https://www.peyroniesforum.net/index.php/topic,12587.msg115941.html#msg115941).

I recommend to everyone to start with vitamin C(ascorbic acid), a very safe substance you can't make much wrong with.
I think it will help in all stages as a basic.
Then maybe add Iodine which is very anti inflammatory, Acetyl-L-carnitine and Magnesium. Once the tissue feels ok and not inflamed I would introduce extending(or manual stretches) and/or VED slowly and carefully(like described in other forums here).


My idea was always to attack the issue from as many useful angles as possible. Using different supplements was part of that.

The most important part to me recovering was consistency.
I hope this was all stated rather clearly.
Title: Re: DMSO+X Revisited 2019
Post by: Deek on May 13, 2020, 07:08:13 AM
Hallo melting,

I have followed your comments with great interest up to this point.
All this DMSO + X story sounds very interesting and promising.

I have already mixed a lot according to your specifications (DMSO + Vitamin C + Xanthan, etc.)

My penis skin is irritated and often burns. Did I take too much DMSO?

The vitamin C powder that I mix feels crumbly on the penis. is this normal or should it dissolve completely?

How many minutes should the mixture remain on the penis?

I thank you in advance.

PS. Kann ich Dich auch mal auf "Deutsch" (PM) hier anschreiben? ;)
Title: Re: DMSO+X Revisited 2019
Post by: melting on May 17, 2020, 03:25:29 PM
You can pm me in deutsch.

to answer the questions:
Quote from: Deek on May 13, 2020, 07:08:13 AM

I have already mixed a lot according to your specifications (DMSO + Vitamin C + Xanthan, etc.)

My penis skin is irritated and often burns. Did I take too much DMSO?

The vitamin C powder that I mix feels crumbly on the penis. is this normal or should it dissolve completely?

How many minutes should the mixture remain on the penis?


-Yes, most probably too much DMSO. Add more water and if the mix gets too runny, premix the water with some xanthan.

-The vitamin C powder should be pre-mixed in water and dissolve completely. Using a mixer that high speed mixes the water and vitamin c (not the dmso part cause most mixers are plastic/iron that could react with dmso) there shouldn't be any hard parts remaining.
But if it's too much powder then it might not dissolve.(then add water) That crumbly could also irritate the skin I imagine.

That said even with a good mix that doesn't burn with 1 application after some continous days or weeks of application the skin might protest. That's why we also add castor oil to it and I recommend to apply something like an aloe vera gel after to help the skin.

But lowering the DMSO parts vs. the other parts will help too. You can then increase the dmso after some weeks a bit...

The mix should remain between 5 and 15 minutes. Most of the DMSO then will be absorbed. Then just add a lotion or creme atop or wash it off.
Title: Re: DMSO+X Revisited 2019
Post by: Dipstick on May 22, 2020, 06:35:59 AM
Melting, what kind of Boron are you using?

I notice there are different forms of it, and is the concentration 10mg per day?

I can find Boric Acid, is that what you're using? Is that a suitable form?
Title: Re: DMSO+X Revisited 2019
Post by: melting on May 22, 2020, 09:12:47 PM
Quote from: Dipstick on May 22, 2020, 06:35:59 AM
Melting, what kind of Boron are you using?

I notice there are different forms of it, and is the concentration 10mg per day?

I can find Boric Acid, is that what you're using? Is that a suitable form?

Natrium Tetraborat (Na2B4O7) Which I took from capsules which have less fillers than the tablets. I only made 1 DMSO mix with it. 
A quick search I found options in germany to just buy the powder.

The pure "Boric Acid" is sold mostly non health or food related though and in germany it was discontinued for use in health products. Some still swear on it's effectiveness. BUT I guess "Boric Acid" needs to be diluted..(!) 
All sources I see on "Boric Acid" seem to be alternative health types..

The "Natrium Tetraborat" seems to be the safe supplement version these days.


Title: Re: DMSO+X Revisited 2019
Post by: MacMathuna on May 23, 2020, 02:12:14 PM
I'm about to order DMSO from amazon, but I want to make sure I'm getting the right stuff.

What I'm looking at says it's 99.995% Pure pharma grade, non-diluted, and purified to be odorless.
Is that fine?

Title: Re: DMSO+X Revisited 2019
Post by: melting on May 23, 2020, 02:42:16 PM
Quote from: MacMathuna on May 23, 2020, 02:12:14 PM
What I'm looking at says it's 99.995% Pure pharma grade, non-diluted, and purified to be odorless.
Is that fine?
Yes, sounds good. I had several brands over the years, always 99% quality and were always fine with it.
Of course you need to later dilute it down, as explained prior in this thread, cause using the pure solution, it will react with water in the skin and heat up causing a burn.
Title: Re: DMSO+X Revisited 2019
Post by: melting on May 24, 2020, 12:34:41 PM
CBD
Molecular weight: 314,464 g/mol

Lot's of CBD oils and cremes available legally  even in prohibitive europe by now. Anti inflamatory properties are known and a lot of research is around on it. 
So, I guess it could help with Peyronies Disease too.

QuoteCannabinoids suppress inflammatory response and subsequently attenuate disease symptoms. This property of cannabinoids is mediated through multiple pathways such as induction of apoptosis in activated immune cells, suppression of cytokines and chemokines at inflammatory sites and upregulation of FoxP3+ regulatory T cells.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/
Title: Re: DMSO+X Revisited 2019
Post by: MacMathuna on May 30, 2020, 11:39:09 PM
Hmmmmm....

I'm mixing the DMSO with water to trigger a heat reaction, shaking the bottle, and then letting it sit until the bottle doesn't feel warm anymore.

But then when I add the asorbic acid+castor oil+xanthan mixture to the DMSO+water, the bottle heats up again like I've triggered a second heat reaction.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 01, 2020, 09:53:06 AM
That's possible. I guess it's when there's more dmso than water to react with. Should be less intense the 2nd time though.
What I sometimes do to speed the process up is to have the water+dmso container/bottle in a cold water bath.

We do it a) to avoid it getting so hot that it destroys the supplements.(but realistically that wont happen for every drop of the supplement added, so no big worries)
b) to have that reaction in the container and not later on the skin.

So I think you should be good with the way you did it.
Try to put the dmso+water container in a cold water bath when adding the supplements. That should mitigate the temperature increase.

Thanks for your feedback, this is still a work in progress on how to mix and do it the best way. 
I'm waiting for a real pharmacist to get in here :)
Title: Re: DMSO+X Revisited 2019
Post by: MacMathuna on June 01, 2020, 01:30:42 PM
I've applied the mix to my forearm a number of times over the course of the last 36 hours, and each time my skin feels itchy & tight and causes small bumps to form on my skin if I leave the mixture on my skin for more than a few minutes.
This hasn't gotten notably better with subsequent applications. :/

I do feel like the DMSO+ACV+castor oil mix I made without Lecithin (the castor oil is able to mix with the ACV, so I skipped the emulsifiers) burns less than the other two mixes which include lecithin. I'm eyeballing the measurements b/c I don't have a graduated cylinder, so it's possible this mix just has a lower ratio of DMSO to other ingredients.

I will try to make a new mix today using more water to dilute the DMSO initially. We'll see if it makes a difference.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 01, 2020, 02:30:10 PM
Quote from: MacMathuna on June 01, 2020, 01:30:42 PM
I will try to make a new mix today using more water to dilute the DMSO initially. We'll see if it makes a difference.

This is the nr.1 way to get any burning or itching down.
Add more water. Rather start with a higher dilution and then increase the DMSO after some time. 

Intersting that the oil and ACV mix for you. They always seperated for me after letting it sit. So years ago I just shook the solution before applying which helped a bit.
Also neither lecithin or Xanthan are necessary and might not be used or used in very low amounts. It's too be able to ease application.

DMSO transdermal permeability starts already at 5%. It considerably increases with 10% and further on.
Companies that sell DMSO products like the DMSO+Aloe Vera gel I saw on Amazon seem to have settled on 70DMSO to 30other as  sweet spot. I read articles or a study where the permeability drops off once the solution is beyond 90-10.
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on June 01, 2020, 06:29:33 PM
Mac, a skin test was a great idea.  As long as you have a reaction to it, u prob don't want to use it on your penis.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 03, 2020, 12:26:05 PM
Tony, I'm very clear on testing on the arm before use on the penis. That's standard.
It's also clear what needs to be done when the solution is too strong for the arm. Easy and logical solution.

Title: Re: DMSO+X Revisited 2019
Post by: TonySa on June 03, 2020, 08:52:49 PM
Melting, the comment was not for you.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 03, 2020, 09:07:22 PM
Your opposition to certain methods is well known. When you post in this thread I automatically assume it's in bad faith.
If not, sorry.
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on June 04, 2020, 06:05:34 PM
Your opinion is I'm opposed to certain treatments, I'm not actually although I do usually recommend any treatment someone wants to try is accompanied by treatments w a track record, such as you added significant traction to DSMO.
Title: Re: DMSO+X Revisited 2019
Post by: Curlywurly on June 07, 2020, 11:12:14 PM
I saw talk of bathing our penises in a DMSO + X mixture.

Any reason why we wouldn't/shouldn't do this perhaps for an hour+ at a time or as long as possible even?
Title: Re: DMSO+X Revisited 2019
Post by: Fix This on June 08, 2020, 05:49:07 AM
Is there an agreeable formula here now ?

There are lots of posts on this thread with different possibilities but I don't there's any agreement about what is good to use ? Apart from DMSO!

I'm about to restart DMSO treatment, will be adding Abscorbic acid and probably use castor oil and Cocunut Oil ( think I'll drop the Emu Oil ).   Is Aloe Vera much different to the above 2 ?

Also was using a mixture of crushed PABA, ACL (and for a time Pentox too )

What are we summarising from this thread ? the 3 or 4 most crucial ingredients to use with DMSO ?


Title: Re: DMSO+X Revisited 2019
Post by: melting on June 08, 2020, 08:29:09 AM
Quote from: Curlywurly on June 07, 2020, 11:12:14 PM
I saw talk of bathing our penises in a DMSO + X mixture.

Any reason why we wouldn't/shouldn't do this perhaps for an hour+ at a time or as long as possible even?

Like putting the whole penis in a glas filled with DMSO+X? I don't know what amounts of DMSO would enter the system that way and if it could be a danger. I guess one could try to do it for some minutes if you do it smart.. and go from there. Start with a low DMSO concentration at first,.. it will work at 5% upwards already. Monitor skin etc.

That said I had days with enough time where I painted my penis all day from a bottle which is similar I guess.
Also there are people, Peyronies Disease unrelated, doing dmso drips into the blood but obvious with such any possible risks increase also.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 08, 2020, 08:42:14 AM
Quote from: Fix This on June 08, 2020, 05:49:07 AM

What are we summarising from this thread ? the 3 or 4 most crucial ingredients to use with DMSO ?
No, not really. But the thread was more a research thread with some brainstorming. I consider making a 2020 thread, more boiled down, easier to read.

I always felt like using every supplement(X) in an extra solution, extra glass.
The reason being, not knowing about interactions and if a "lower weight molecule" of supplement X1 and a "higher weight molecule" of X2 change how it works.
So that's why I present different X supplements that could work. At times I had 10 glasses that I cycled through.

But totally possible that using 2-3 supplements in one could work too.. idk. Check the interactions. I think Vitamin E + C can work for example.. But mixing C and Magnesium would create an interaction, possibly increasing the weight too.

Aloe Vera is different but basically helps the skin deal with the dmso. You can test how it mixes.. Castor oil itself has some good ingredients too.

PABA, ACL and Pentox are great. I always felt to using different supplements with different ways working on plaques helped(attacking from different angles). I would suggest using a stable like DMSO+Vitamin C(ascorbic acid) and then apply every other application different DMSO+X supplements.
Title: Re: DMSO+X Revisited 2019
Post by: samsung on June 08, 2020, 09:43:46 AM
Would it be possible for someone to boil down an easy instruction type manual without having to digest a massive amount of info? Like a highlights type of thing. I would want to know:

1. What percent DMSO mixed with either water or Aloe and where to get it.

2. How to store it.

3. How many times a day to apply it.

4. What are the main things to mix it with and where to get those and how to mix them.
Title: Re: DMSO+X Revisited 2019
Post by: Fix This on June 08, 2020, 06:08:56 PM
Did anyone try silica gel with DMSO in the end ?

Title: Re: DMSO+X Revisited 2019
Post by: melting on June 09, 2020, 08:00:40 AM
Silica - I didn't. If you do, use some product that you can find in health stores or as natural supplement. Nothing "chemical" or "industrial".

Samsung,
I will do soon a new thread with everything boiled down to the essentials.
1. DMSO from pharmacy or Amazon. I bought a lot of different types and all worked. Pure 99% quality DMSO, phamaceutical grade. You can mix it from 5%(of the solution as in 5parts/of100parts) to 90% with Water. I did mostly use 70% DMSO + 30% water and "X". Some people need to start with ~50% or they get slight burning.
2. Brownglass, like you get in a pharmacy. Keep cool but note that DMSO will freeze above water freezing point 0°C, so outside the freezer. When using it daily you can keep it in the bathroom.
3. As often as possible. 1-3. But you can do it all day as long as the skin is OK and the supplements("X") amounts are within the healthy margins.
4. Pure Ascorbic Acid(Vitamin C) powder(every grocery store in germany has it) is the easiest and safest to use and I would recommend to start with.

50% DMSO + Ascorbic Acid(VC):
You need
-DMSO.
-Ascorbic Acid powder.
-Brown glass bottle with "glas eye dropper" ~100ml
-some glass for mixing. Easy to pour into the brown glass from.
-wooden "stick" for mixing (no chemicals, metal or plastic on it).
-Know about the dangers of DMSO. (no contact with poison, chemicals or plastics while handling or using. Pure DMSO might burn your skin)
You can get all of these easy, searching google for shopping, amazon, pharmacy etc.

Then do this:
-Fill the Brown glass bottle half(50%) with DMSO. Add 10% clean water. Move it a bit. Heat reaction. Let it cool down.
-Put clean water into the other glass.(enough to fill up the DMSO bottle). Add Ascorbic Acid powder and mix it until the water is saturated(no powder visible)
-Pour the water+Vitamin C mix into the DMSO brown glass. You can mix it with the "wooden stick" or shake it gently. Wait until any heat is gone and then you can add more ascorbic acid directly into the mix until it's saturated.

That is a very basic DMSO mix.
It's watery, runny but you can apply it with the glass eye dropper to the penis, some drops or "paint it". Let sit for 5-15 minutes. Wash off with clean water and/or use a healthy lotion ontop.

One can add some steps to create an easier to use and apply solution with oil, emulsifiers etc.

That's again a lot of words, but it's all very easy. I can do a mix in <5 minutes.
The problem is to understand handling DMSO and being smart about applying the solution, test on arm etc. There will always be some guy doing it all wrong if I just trust peoples own responsibility and hence I have to write it all with warnings etc. every damn time lol
Title: Re: DMSO+X Revisited 2019
Post by: samsung on June 09, 2020, 08:32:52 AM
Thank you sir. Much appreciated. One last question...

I read that old Thacker's formula thread from like a decade ago and they mentioned using a clean cotton rag. They soaked the rag in the DMSO solution (ACV, DMSO and castor oil I believe) and wrapped the penis in it. It would seem this might be better than putting with eye dropper because you are really bathing the penis in the solution. Any thoughts? And if you did this, what sort of cloth would you use because I would think any cotton nowadays is going to have some sort of nasty chemical on it somehow.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 09, 2020, 03:04:12 PM
Yes, that's Thackers in a nutshell. Some wrapped it around and kept it on for hours. I did it 2-3 times I think.
Was always a mess though and smelled horrible lol. That's one of the reasons the thackers wasn't used as much and as it should be.

The DMSO is gone fast in any case. Once it's on the skin it "seeps through". It's certainly possible that any supplements on the skin might penetrate for some more minutes or hours, Castor oil itself has some transdermal properties(nothing like dmso though). For near skin plaques it might be useful but generally the transdermal effect goes down exponentially after 5-15 minutes.
I always felt like doing several DMSO+X applications, (once used to dmso after some weeks), daily, possibly continuously for some hours, was very effective. I did that at least once a week. Basically "painting over" the rest of the supplements over and over.

I think it's a great idea to have now and then a classic Thackers wrap though, why not. Despite the lore story about it like from some us western movie, snake oil type, I'm convinced it worked for "Thackers" and has an effect. ACV for example has a lot of ingredients that are theoretically beneficial to peyronies. I used a lot of DMSO+ACV. (it stinks, a lot though)

Title: Re: DMSO+X Revisited 2019
Post by: Fix This on June 09, 2020, 05:37:07 PM
You can actually buy Castor Oil packs which are basically a bottle of castor oil and a large cotton bandage! The idea of these is to get the castor oil into the required body part over a prolonged period with this. The penis was not necessarily what they had in mind but the same principle will apply ofcourse! Chuck some DMSO and your X ingredients in and that work quite imagine I would imagine

Title: Re: DMSO+X Revisited 2019
Post by: melting on June 09, 2020, 10:19:56 PM
Yes it will have an effect on its own.
With the DMSO we really push the supplements, castor oil, through the tissue and the plaques. It's a big difference to just the oil.
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on June 09, 2020, 11:22:23 PM
If you have burning pain w DMSO, or any other treatment, I recommend you stop and back off to the point of no pain.  No, melting this is no anti-DSMO and applies to any treatment strategy that causes pain
Title: Re: DMSO+X Revisited 2019
Post by: Sadman1 on June 10, 2020, 06:15:21 PM
Just stumbled upon this thread. I was going to use the original thackers formula. Would vit c + DMSO be better?
Title: Re: DMSO+X Revisited 2019
Post by: Sadman1 on June 10, 2020, 06:28:40 PM
I bought some 10cc syringes from amazon. anyone know if these will react with DMSO?

https://www.amazon.com/gp/product/B013WWFJX0/ref=ppx_od_dt_b_asin_title_s00?ie=UTF8&th=1
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on June 10, 2020, 11:26:50 PM
Avoid plastics, use glass only and 100% pure cotton cloths (if used) w no additives.  This is a serious concern w DMSO as it can bring contaminants into your penile tissues—not good!
Title: Re: DMSO+X Revisited 2019
Post by: Fix This on June 11, 2020, 06:08:36 PM
Hi Melting

I've received Ascorbic Acid that I ordered on the back of this thread

Haven't used it with DMSO yet . Before I do, are there studies or results that suggest this is good for this purpose?  Or is it just that it has a low molecular weight ? I wanted to check this before I started using it

The thought also crossed my mind that excess vitamin C ( ascorbic Acid ) is thought to be factor in causing the peyronies scars to develop in the first place. As excess Vitamin C can lead to excess Collagen production I do believe. And at the time of injury ( or days afterwards ) t while he body is attempting to heal , the excess vitamin C can then cause excess Collagen can be produced at the site of healing. That's the theory anyway I believe. In fact, at the time of my Peyronies injury I was taking high strength Vitamin C timed release capsules every day ( 1500mg I think ). May have been a factor or just a coincidence .

So just wondering whether this could be an issue with the Ascorbic Acid. Or if is conversely beneficial during stable phase peyronies once the initial scars/ plaques have formed

Any thoughts or knowledge on this ?
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 12, 2020, 07:23:59 AM
Quote from: Sadman1 on June 10, 2020, 06:28:40 PM
I bought some 10cc syringes from amazon. anyone know if these will react with DMSO?

https://www.amazon.com/gp/product/B013WWFJX0/ref=ppx_od_dt_b_asin_title_s00?ie=UTF8&th=1

As you probably found out already, plastic can react with DMSO. But there are certain plastics that dont react at all. Some sell DMSO in these plastics.
Here's a big list: http://tools.thermofisher.com/content/sfs/brochures/D20480.pdf  of plastics and DMSO is down the line.
HDPE plastic doesn't react for example.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 12, 2020, 07:28:28 AM
Quote from: TonySa on June 09, 2020, 11:22:23 PM
If you have burning pain w DMSO, or any other treatment, I recommend you stop and back off to the point of no pain.  No, melting this is no anti-DSMO and applies to any treatment strategy that causes pain
BS. There's a specific reason well known reason why it burns. If you put it undiluted on the skin it will burn. 
You need to dilute it and everyone paying attention knows that. It's easy.

I explained it in detail RIGHT ON THIS PAGE which you conveniently OBFUSCATE for some phony reason, but again, it's transparent, you are here in bad faith promoting nonsense all over the place.(like traction while you are inflammed, dangerous and dumb).

The only thing you promote is implants..(its for old people who have no idea how to fix themselves, like you) even to young totally fixable guys...I don't like you.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 12, 2020, 07:59:54 AM
There are NO direct PEYRONIES STUDIES with ANY of the talked about DMSO+X supplements(I know of)!!!!! 
And most probably there never will be. (no profit in this)

If someone doubts it, like the Tony's of this forum, then research it or don't do it and instead get your dick cut up and get an implant, easy way out. This here is the hard way. All your own responsibility. That's not directed at you "Fix This"! Just getting riled up about some ignorant people. Sadly lot's of dummies who can't take responsibility for their own life and cry when they do their crap wrong blaming others.

ok.. :)

Quote from: Fix This on June 11, 2020, 06:08:36 PM
So just wondering whether this could be an issue with the Ascorbic Acid. Or if is conversely beneficial during stable phase peyronies once the initial scars/ plaques have formed

Any thoughts or knowledge on this ?

I promote it as the prime DMSO+X mix cause it's easy to create, cheap and VItC is completely harmless, almost impossible to overdose or hurt anything with it. It's the safest supplement - Ascorbic Acid.

You can research vitamin C in connection with tissue, veins, fibrosis, scars, etc. and make a logical conclusion towards peyronies..
It's anti-inflamatory, it's an antagonist to calcium desposits, needed to build healthy FLEXIBLE tissue..

To me it makes no sense to assume that vitamin C creates faulty tissue. I doubt that the body will overproduce collagen just cause VitC is there. If you leave out the building blocks of Collagen you will get faulty collagen.
Without vitamin C(and others) the body will patch up the inflamation or injury with other materials resulting in fibrotic clumps.

It's interesting you took C and still got peyronies. But most C we orally take in is gone fast, - short half life. That's why coating the site of the plaque with it as often as possible transdermaly is much more effective than having it systemic and with low blood flow to the penis it wont reach the 'building site'. (it's still good to also have VC systemic taking it orally)
Also Vitamin C, while essential, obviously other supplements/chemicals are involved too.

At best you would start DMSO+Ascorbic Acid to get used to the procedure, to know how much you have to dilute the DMSO etc.
Then you would start some other solutions with supplements that help in your situation. For example dmso+Iodine or dmso+Magnesium.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 12, 2020, 08:02:20 AM
I finally blocked Tony and his trolling ignorance.
If he keeps posting nonsense on this thread, know that he has no clue about DMSO+X.
Title: Re: DMSO+X Revisited 2019
Post by: sinvanio13 on June 12, 2020, 08:51:05 AM
Hi, @Melting
i am coming back after a confinement absence, ^^ , i am about to test asc Acid and Iodine in seperate days.
I have a question about Iodine, i found Harmonic Innerprizes Nascent Iodine at amazon, but coming from canada/usa, quite expensive , did you manage to find an equivalent without unsuitable additives ?

Another point  there was recently a post promising about oral Copper Supplementation (depleted by zinc supplementation)
did you investigate that topical  or orally? https://www.peyroniesforum.net/index.php/topic,13065.0.html
thanks
Title: Re: DMSO+X Revisited 2019
Post by: hope794 on June 12, 2020, 06:45:35 PM
Questions for melting (and for the other users who cured Peyronie's with this method):

1. I've understood that i have to apply DMSO+X at least 3 times a day, for 10minutes. Then i wash my penis with normal water, for example using the water from a sink?

2. You've spoken about Iodine, and u said that it is antinflammatory. But i found poor evidence about it online. Can you please share something of the papers you read here? :) Furthermore, where to buy iodine? I didnt find anything on amazon, except for tablets. Should i break them and mix with DMSO?

3. Should i wash my penis with soap too, after i washed the DMSO away with water?

4. Should i apply some kind of oil or cream to give reliefe to the penile skin in the night? For example castor oil, or aloe vera, (without DMSO)?

Thank you really much!
Title: Re: DMSO+X Revisited 2019
Post by: sinvanio13 on June 12, 2020, 08:14:37 PM
Quote from: hope794 on June 12, 2020, 06:45:35 PM
Questions for melting (and for the other users who cured Peyronie's with this method):


2. You've spoken about Iodine, and u said that it is antinflammatory. But i found poor evidence about it online. Can you please share something of the papers you read here? :) Furthermore, where to buy iodine? I didnt find anything on amazon, except for tablets. Should i break them and mix with DMSO?

i sent you a private message for the link on amazon for the brand i ordered this week (expedition from the USA eligible to prime delivery)
Title: Re: DMSO+X Revisited 2019
Post by: hope794 on June 12, 2020, 09:53:45 PM
Thank you very much bro, but i didnt receive any PM yet..!
Title: Re: DMSO+X Revisited 2019
Post by: Fix This on June 13, 2020, 05:52:24 AM
Hi Melting

Thanks for your reply. No I was refering to general studies regrding Vitamin C and peyronies rather than using DMSO and transdermal. As you rightly say I believe, that transdermal application of anything should get much more of the product to the plaques than orally. So anything that applies to a particular agent when taken orally should in tehrory apply when applied transdermally. Only with much more efficiacy ( we think! ). Anyway, I'll look into the Vit C a little bit more I think before I use that one

Can I ask, what sort of curvature and/ or narrowing did you have before you started this treatment ? And how much improvement have you had since starting your DMSO + X treatments ?

I'm going to go a bit heavier on this DMSO treatment (+X) and I think your idea of having many separate bottles with individual substances in and rotate them is excellent. I'm going t order some more bottles and try some of the other agents mentioned here

I already have Castor Oil, PABA, ALC, Vit E, Ascorb Acid, Pentox, Coconut Oil ( dropping the Emu Oil I also have )

Can you recommend any of the other compounds mentioned on this topic ? Iodine and Magnesium ( any type ? ) have been mentioned recently, but there are many more reading back through this topic that have been mentioned once , but not again.

Have you or anyone else here had any particular success with any specific ' X ' products ?

Title: Re: DMSO+X Revisited 2019
Post by: Fix This on June 13, 2020, 06:58:09 AM
Sorry , another question Melting. I need to order some more glass bottles. Is there a reason that you mention brown bottles rather than clear or blue ones ?

Thanks

Fix
Title: Re: DMSO+X Revisited 2019
Post by: sinvanio13 on June 13, 2020, 08:25:33 AM
Quote from: hope794 on June 12, 2020, 09:53:45 PM
Thank you very much bro, but i didnt receive any PM yet..!
sorry i dont know what t happened cant see my message in sent items mailbox.
i sent you again plz confirm you ve got it
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 14, 2020, 02:38:13 PM
Quote from: sinvanio13 on June 12, 2020, 08:51:05 AM
Hi, @Melting
IODINE

I think I would pay for 40€ for 30ml. That's very expensive and if you're not rich for basically 1 time buy. I used 1 bottle 50ml I think over several months as part of a multi DMSO+X range of bottles.
You probably can use the "LUGOL's" Iodine too. Obviously read up a bit on it on google etc. and be aware of dosage etc. and test  llittle bit on arm before using it a lot.

COPPER
Yes and if you make forum wide search for copper + DMSO you will find it discussed by me and others. There are many copper versions. I had one that I can't remember.. Copper sulfate maybe.. With minerals like iodine or copper be aware that overusing them can deplete other minerals.(but hard to do with the amounts we use in dmso+x in most cases)

Also wise to use Vit C and for example iodine not in same bottle or same time cause they interact with each other too much.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 14, 2020, 03:07:17 PM
Quote from: Fix This on June 13, 2020, 05:52:24 AM
Hi Melting

Yes, whatever might work orally might work transdermally, of course molecular weight and how it theoretically works needs to be understood. IDK maybe something works better when moving through stomach etc.

Vitamin C is the safest. Hard to do anything wrong with it. The body loves it. Only we and a handful of animals don't produce our own Vitamin C.

- Several places on shaft hourglass and slight bend and a "torque", and soft places with no erection. All solved as explained several times here. I'm 100% functional. Traction and VED very important for me. I also talked about.

-Magnesium and Vitamin C were a staple for me. Also in my last run months ago, to get rid of the last plaque remains, I felt like "Natrium - Thiosulfate", also discussed here, had a great impact.

-It's hard for me to nail it to one supplement as I most times used several. I believe all of them worked in some form.
There most probably is an optimal way, how to cycle through supplements for best non negative interactions and best positive reactions related to where the peyronies stage is.
That would need a lot of professional people to nail down. I attempted discussing active and established plaque supps on this thread and someone chimed in. page 2-3 I think. Anti Inflammatory during active phase and anti-calcification/scar/fibrosis during hard/established stage. BUT there are good reasons to use both all the time, just maybe a bit less.

Quote from: Fix This on June 13, 2020, 06:58:09 AM
brown bottles

light - Supplements degrade slower in brown glass.
Ascorbic acid within hours/days when put in water and in direct light. In dark 2-3 weeks.
Best, cool, dark but not below 6°C cause DMSO freezes earlier than water(0°C)

Title: Re: DMSO+X Revisited 2019
Post by: melting on June 14, 2020, 03:33:30 PM
Quote from: hope794 on June 12, 2020, 06:45:35 PM
Questions for melting (and for the other users who cured Peyronie's with this method):


1. Most the times I mix what remains on my penis with a good lotion and then the skin is OK and everything is gone.
But if you have safe water from the faucet you can use that too. Like going into the shower after application. Just dont use some super aggressive shampoo right over it.

2. For example: https://pubmed.ncbi.nlm.nih.gov/19168293/ , best way is to search for scars + X(iodine) , keloids+X, plaques+X, fibrosis + X, inflammation+X , tissue+X etc.

3. answered in 2.

4. Yes. Helps a lot. Can apply right after DMSO too.
Everyone has to test what works for their skin in what concentration.

Nascent Iodine or lugol's. It's liquid. Might have to ask pharmacy online or local.
Problem with grinding tablets is that they have a lot of filler material. Not necessarily harmful. The result most time is that you have remaining clumps in the solution or on your skin after application. I did that for some supplements, it's messy, but possible.

Title: Re: DMSO+X Revisited 2019
Post by: hope794 on June 14, 2020, 04:57:52 PM
Thank you for the reply!
Title: Re: DMSO+X Revisited 2019
Post by: Bent Ding Dong on June 16, 2020, 06:53:11 AM
I'd love to try DMSO again but the garlic smell coming out of my skin and breath is a bit much especially when you have to go to work smelling all day. If anyone knows of a non smelling DMSO can you let me know? I've heard some say pure DMSO doesn't have as much smell.
Title: Re: DMSO+X Revisited 2019
Post by: projectpd on June 16, 2020, 02:40:11 PM
I've bought DMSO twice , first time claiming 99.8% pure in a cheapy looking plastic bottle and later "upgraded" to 99.99% pure in a nice brown glass bottle. the 2nd one was solid (jelly like) at a temperature that the 1st one wasn't and came with a note saying that if so , this was a sign of its purity, which seems reasonable. But both of these only have a rather faint (to me, I don't have the best sense of smell though) odour that is not unpleasant at all. Also all the reports on it say you can taste garlicy
flavour in the mouth within seconds of putting it on your skin, but I'm not sensitive enough to have detected this! I know some people have much more sensitive noases/tastes.  However I have a dmso+x style concoction (mostly a la Thackers) with #2 that truly reeks of a garlicy odour. So beware, probably depends what it reacts with.

THere are other things that have been studied for transdermal properties, it's a huge volume of research .

There is a ton of research on variations of liposomes, lots of "X-somes" with variations on X. Some of the latest are Invasomes (adding small fractions of terpenes, which are in essential oils such bitter orange, lemon, lavender. TransEthosomes (adding significant fractions of Ethanol -  the optimal proportions exactly match that in vodka!). These typically use phosphatidyl choline (a component of soy or sunflower lecithin) and a small fraction of surfactants (such as in detergent, but there are pure  and natural(ish) options). These make the vesicles very flexible so they can squeeze between skin cells without breaking up.  It's easy to make liposomal vit C at home , there are youtube vids on this and at least one that actually demonstrate with a microscope that the liposomes are small enough. Therefore I believe many of the more effective variations are probably easy to make. Ethanol has an advantage that it will help to preserve the mixture. otherwise it could go off in a few days.  Ethanol does sting however.
In a study on transdermal serrapeptase, DMSO and Isopropyl Myristate were credited with effectiveness, in a comparison where many other candidates didn't.
serrapeptase has a huge molecular weight. I got some ! it has no smell at all.

Also other general factors are bound to be relevant such as pH, temperature, hydration. Not always in the most obvious way, I read a paper where hydration was thought to be detrimental to the agent's absorption, purportedly it might detract from the hydration gradient that  helped that substance to penetrate.

I have been wondering if other factors would also help, such as while using a stretcher (opens up spaces between skin cells) , VED (same).

3Mhz ultrasound (cheap devices available).

Percussion massager. These go up to 10,000 Hz. Don't really know if this should help, just a hunch.


Title: Re: DMSO+X Revisited 2019
Post by: Fix This on June 16, 2020, 04:26:21 PM
Thanks for your replies Melting. And good post too ProjectPD

Has anyone else experienced any lines on their penis after DMSO use ?

I'm seeing a few horizontal lines / wrinkles around the area of the plaque that I've been targetting a lot more in the last week or so. I'm fairly sure I don't recall seeing these previously. I suspect I may have used a bit too much DMSO in some of recent mixes. I'm hoping these are temporary. Will be moisturising them pretty intensely and may lay off the DMSO until I can see an improvement in them

I've always left the DMSO and X on the skin to dry and just left it on until next shower. I think I saw some mention of washing off once it had dried on here? Just wondering whether this might be a factor here
Title: Re: DMSO+X Revisited 2019
Post by: hope794 on June 16, 2020, 06:25:10 PM
Fix this, probably rough veins?

It happens to me when i got pretty good erection (thanks to pde5i). I notice things that normally i dont notice due to the more engorgement. DMSO improves blood circulation: maybe you're experiencing this?
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 16, 2020, 09:46:40 PM
If the skin is tight then its most probably dried out.
If it's soft watery then most probably fluids/parts of the solution accumulated due to the dmso opening up the layers.

Normal to run into skin issues after some continuous applications. Cut back or use lotions/etc. that help the issue at hand.
I had to stop several times after some weeks to let the skin catch up. Depends a lot on the X. Ascorbic acid can accumulate in skin if applied daily. In nails it will store and slowly degrade changing color.(which is harmless, just a different form of Vitamin C).

I applied DMSO+VC for some days with my hands and I had for some days yellowish nails. Looked weird lol

I wonder how dmso+ anti calicification agents would influence nails that have these white spots in them(I think its calcium deposits?)
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 16, 2020, 10:00:09 PM
Quote from: projectpd on June 16, 2020, 02:40:11 PM

In a study on transdermal serrapeptase, DMSO and Isopropyl Myristate were credited with effectiveness, in a comparison where many other candidates didn't.
serrapeptase has a huge molecular weight. I got some ! it has no smell at all.

Also other general factors are bound to be relevant such as pH, temperature, hydration. Not always in the most obvious way, I read a paper where hydration was thought to be detrimental to the agent's absorption, purportedly it might detract from the hydration gradient that  helped that substance to penetrate.

I have been wondering if other factors would also help, such as while using a stretcher (opens up spaces between skin cells) , VED (same).

3Mhz ultrasound (cheap devices available).

Percussion massager. These go up to 10,000 Hz. Don't really know if this should help, just a hunch.

I researched that a bit maybe posted on the forum about it and I thought it was not feasible to use Serrapeptase. Didn't they use a special form of it?
It's an interessting product though. Nattokinase and Serrapetase. I used 2 bottles of it orally and I have no idea if it helped.. probably had some effect..


Yes, just using dmso+X will most probably not solve peyronies easily. Especially thicker plaques. I often mentioned to use traction, VED etc. along with it.
I used an extender and while stetching applied DMSO+X (dont let plastic or metal come in contact with it)
I doubt it would've solved my Peyronies Disease without traction and VED.
Though I always observed that the plaques itself slowly lost substance after weeks of only dmso+X. The small remaining ones I had are gone after 3-4 months daily excessive applications.

Theoretically, the idea with the utlrasound and massager is to mess with the structure of the plaques. Again, in itself probably not enough but combined could have a compound effect.. The structure opening up allowing the dmso+X to easier get in and remain and then(not so likely) for the body to "reclaim" space with normal blood cells and material. Similar can happen with visible scars on skin.

Making the plaques flexible and increasing the size/stretch of the tissue around them was enough for me to revert most peyronies effects.

Title: Re: DMSO+X Revisited 2019
Post by: Dipstick on June 17, 2020, 02:52:44 AM
Looking at superoxide dismutase.

I noticed it's molar mas is high? 32 kDa?

That's 32,000 g/mol right? So I doubt it can be used with DMSO then.

I don't understand if that is possible to be used as a transdermal. While its used in H100 cream.
Title: Re: DMSO+X Revisited 2019
Post by: projectpd on June 17, 2020, 02:40:10 PM
don't know for sure considering serrapeptase.  don't think the study i was referring to used a special form of it. But there were a couple of studies on transdermal SOD using a "conventional liposomes" form by Claus Riedl.  https://pubmed.ncbi.nlm.nih.gov/15982798/
it was a human form , super expensive and only available to labs. only 2mg /day. but a melon derived form looks very cheap at 21mg * 60 for 25$.  did good stuff for hamsters https://www.nmcd-journal.com/article/S0939-4753(09)00108-2/abstract

Title: Re: DMSO+X Revisited 2019
Post by: melting on June 17, 2020, 04:19:11 PM
QuoteSOD using a "conventional liposomes"
That was it! Everything reasonable that can help with no danger one can try. I checked the original study you linked and it seems they used normal serrapeptase, if it works in reality, for us.. I don't know.
That said, what we already have researched and tried is enough,in combination with other treaments(traction+ved+*xyz*) to get rid of peyronies symptoms. Dosage and frequency are important. The more of it, the more often, the better(WITHOUT causing any harm, obviously.).

Quote from: Dipstick on June 17, 2020, 02:52:44 AM
Looking at superoxide dismutase.

I noticed it's molar mas is high? 32 kDa?

That's 32,000 g/mol right? So I doubt it can be used with DMSO then.

I don't understand if that is possible to be used as a transdermal. While its used in H100 cream.

WHY do you look at it?

QuoteSuperoxide dismutase (SOD, EC 1.15.1.1) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O2−) radical into ordinary molecular oxygen (O2) and hydrogen peroxide (H2O2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage.[2] Hydrogen peroxide is also damaging and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is Lactobacillus plantarum and related lactobacilli, which use a different mechanism to prevent damage from reactive O2−.
https://en.wikipedia.org/wiki/Superoxide_dismutase

That sounds not so good in combination with DMSO.

The options available already work and have effects. A miracle stubstance would be great. Overnight dissolve of the plaque and fibrosis. That's what sometimes seem to work with xiaflex.(with the fitting circumstances)

But unlikely. All buy for home ways to get rid of scars on the body takes a lot of time. No known miracle creme, right..?
Cumbersome daily tedious use of several measures. Takes a lot mentally. Need to be healthy and without stress too.

I hope some pharmacist or similar will be able to formulate practical "potions" with transdermals that can be used in a way that fits.

Start with ascorbic Acid. It's one the most important supplement for humans. No Ascorbic Acid = DEATH. 99% of mammals

Title: Re: DMSO+X Revisited 2019
Post by: melting on June 17, 2020, 04:25:56 PM

QuoteVitamin C is important in wound healing. Without enough vitamin C, a person can get a sickness called scurvy. Lack of vitamin C was a serious health problem on long ocean trips where supplies of fresh fruit were quickly used up. Many people died from scurvy on such trips.

Most animals make their own vitamin C. Some mammals cannot. Those that cannot include the main suborder of primates, the Haplorrhini: tarsiers, monkeys and apes, including humans. Others are bats, capybaras and guinea pigs.

QuoteFunctions of vitamin C in the body
In living organisms, ascorbate is an antioxidant, since it protects the body against oxidative stress.[1] It is also a cofactor in at least eight enzymatic reactions, including several collagen synthesis reactions that cause the most severe symptoms of scurvy when they are dysfunctional.[2] In animals, these reactions are especially important in wound-healing and in preventing bleeding from capillaries.

https://simple.wikipedia.org/wiki/Vitamin_C#Vitamin_C_deficiency
Quote
High doses (thousands of mg) may result in diarrhoea, which is harmless if the dose is reduced immediately. Some researchers (Cathcart) claim the onset of diarrhoea to be an indication of where the body's true vitamin C requirement lies.

The small size of the ascorbic acid molecule means the kidneys cannot retain it in the body. Quite a low level in the blood serum will cause traces to be present in the urine. All vitamin C synthesising mammals have traces in the urine at all times.

WHICH MEANS: You are loosing continuously vitamin C !!!

QuoteAlmost all mammals manufacture their own vitamin C in amounts equivalent to human doses of thousands of milligrams per day. Large amounts of the vitamin are used in orthomolecular medicine and no harmful effects have been observed even in doses of 10,000 mg per day or more.

___________


DMSO+VITAMIN C


Easy to mix, easy to use. If you know how to use DMSO(READ UP ON ITS DANGERS) then it's a very effective way to bring Ascorbic Acid directly to the plaques.
Only side effect, besides dmso which can burn skin in too high dosage(AND MANY CONTROLLABLE DANGERS), is staining of skin, especially in nails with direct contact of dmso+ascorbic acid.
It's the most researched and cheapest 'supplement' in the world. Read up on it.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 17, 2020, 05:01:12 PM
QuoteSuperoxide dismutase is known to reverse fibrosis, possibly through de-differentiation of myofibroblasts back to fibroblasts.[54][further explanation needed]
wiki
Interesting

Quote from: Dipstick on June 17, 2020, 02:52:44 AM
Looking at superoxide dismutase.
I noticed it's molar mas is high? 32 kDa?
That's 32,000 g/mol right? So I doubt it can be used with DMSO then.
I don't understand if that is possible to be used as a transdermal. While its used in H100 cream.

It's used for superficial scars and to penetrate them deep I guess.
Theoretically that's too much weight but above Serrapeptase seemed to work too. I guess due to the high weight the total amount transported is minimal.. maybe idk.

I, FOR A FACT, know that almost all of the Ascorbic Acid moved deep into the body. I'm not 100% on all the other supplements I used. Sometimes feels like a lot remains on the skin. With Vitamin C it's ALMOST like I can feel it going through the body. With nails for example it does.
That's cause of it's ultra low weight. I SATURATE all dmso+ascorbic acid potions with ascorbic acid, meaning nothing dissolves and crystals remain clear remaining. 176,12 g/mol
AND it readily dissolves in water in large amounts. 330 g/L !

https://en.wikipedia.org/wiki/Chemistry_of_ascorbic_acid

https://en.wikipedia.org/wiki/Vitamin_C_megadosage#Adverse_effects

QuoteAlthough vitamin C can be well tolerated at doses well above what government organizations recommend, adverse effects can occur at doses above 3 grams per day. The common "threshold" side effect of megadoses is diarrhea. Other possible adverse effects include increased oxalate excretion and kidney stones, increased uric acid excretion, systemic conditioning ("rebound scurvy"), preoxidant effects, iron overload, reduced absorption of vitamin B12 and copper, increased oxygen demand, and acid erosion of the teeth when chewing vitamin C tablets.[1] In addition, one case has been noted of a woman who received a kidney transplant followed by high-dose vitamin C and died soon afterwards as a result of calcium oxalate deposits that destroyed her new kidney. Her doctors concluded that high-dose vitamin C therapy should be avoided in patients with kidney failure.[28]

The woman died cause the vitamin C dissolved/reacted with the calcium in her body(possibly also harmful calcium deposits).
Quote
Overdose
As discussed previously, vitamin C generally exhibits low toxicity. The LD50 (the dose that will kill 50% of a population) is generally accepted to be 11,900 milligrams (11.9 grams) per kilogram in rat populations.
[/b][/u]

Which means a 100kg person would THEORETICALLY need 1kg of ascorbic acid to die with a high %.

of course..
Quote6.3  Biological half-life by route of exposure

             The plasma half-life is reported to be 16 days in
             humans. This is different in people who have excess levels of
             vitamin C where the  half-life is 3.4 hours (Dollery,
             1991).

So you need to take a lot of ascorbic acid at once for a long time to create a problem. With whatever excsessive means I used dmso+ascorbic acid I never was anywhere near any toxic amounts and I sometimes used it 1 day all day.

THE KEY with DMSO+ASCORBIC ACID is obviously to use it as often as possible IF you want a lot of ascorbic acid around and inside the plaque. I THINK using it all day once a week or a months in big but healthy amounts can possibly deposit a lot of ascorbic acid via DMSO inside the plaque/fibrosis. CAUSE once it is inside the NOT NORMAL PEYRONIES TISSUE it will stay inside like it stays in nails. I THINK it make sense to use a handful of other healthy supplements+DMSO along with C every other day or application to compliment it. WHILE obviously making sure to use DMSO in healthy amounts.(READ UP ON DMSO and its dangers first 1-20 results google search. )
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 17, 2020, 05:12:55 PM
OBVIOUSLY

all with your own responsibility. I answer questions and answer to my best knowledge but I AM NO DOCTOR.
It's experimental and DIY and only for smart people who dont freak out without good reason.

IF YOU DONT KNOW ABOUT KNOWN DANGERS in time of google and unlimited access to most information its your problem.
Inform others about mishaps please and dangers you know about. 

But every danger you can read on google first 1-5 pages results and fall victim to, not on accident, you can't blame anyone else.
I burned my dick accidently with DMSO and it was kinda horrible but it's known and was only my fault. Learned from it and carried on and skin was brand new soon.
Title: Re: DMSO+X Revisited 2019
Post by: hope794 on June 17, 2020, 06:46:17 PM
Hello  everyone (especially melting, please read this bro lol)
Finally, today, DMSO and all the stuff arrived. I have:
DMSO ; Purified water ; Vit. C ; ALCAR ; Metformin ; Castor oil ; Xanthan gum; Iodine.
Today, i've tried to mix DMSO and purified water.

First of all, i used 30% DMSO and 70% Water or my arm to see if i had any adverse effect. NO EFFECTS.
After that, i've used 50% DMSO and 50% water on my arm, no effects so far, not even a burning sensation/feeling.
Tomorrow, i will probably go straight up to 70% DMSO, as stated in this post.

Furthermore, as melting said, the solution is really watery. I'll try to mix some xantan. Actually i've already tried to do so, but it came off a strange thing, like the xantan "agglomerated". Strange.

So my questions are:

1. It seems really strange to me that i didnt have any burning even with 50% DMSO. Is it normal? (Note that i've only used like 4 drops, not more!)

2. How many drops / mL must i use on the penis?

3. Should i massage the penis to spread the DMSO all over it (especially the plaque) after i've put the drops?

Thank you really much, i'll update you !!!

P.S. = it was a little bit sad to hear melting say that dmso+x only will not make the work :(

P.P.S = I was thinking about something.. even if i put 6mL of solution everyday, aren't the ingredients still too little for the plaque? Probably only some Milligrams really reach the plaque (like 10-20mg at best!) What do you think about it, guys?
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 18, 2020, 07:46:16 PM
Quote from: hope794 on June 17, 2020, 06:46:17 PM

Furthermore, as melting said, the solution is really watery. I'll try to mix some xantan. Actually i've already tried to do so, but it came off a strange thing, like the xantan "agglomerated". Strange.


Yes XANTHAN will clump! You need an electric mixer. That's why it's a 2 part process.
DMSO+ some WATER heat reaction 1 glas. Then mix the X-Supplement with some other water in another glass and add XANTHAN to that AND THEN use a mixer, electric one, the ones you can operate with one hand and mix it thoroughly.
ONLY THEN add it to the DMSO+water mix and stir or shake it all WITHOUT the mixer cause OBVIOUSLY you don't want the metal and plastic of the mixer to interact with the DMSO. You can use a glass stirer or a wood stirer or just shake the glas carefully.

Also if the mix is still too watery you can mix some Xanthan in not much water and add that to the mix to make it more lotion like.

1. totally normal, different for everyone, some burn earlier some not at 95% and react at different points, so still be cautious with private parts. Beyond 90% I got problems. Sometimes problems only happen after some continious days of application. Easy solved.. cut dmso back and dilute with water and the supplement.
2. Enough to allow the dmso+X to reach the plaque.
3. Not necessarily. The dmso will readily absorb. But you can. Just note that this also moves the solution into your hands.

4. It maybe can, especially if done optimally, which I don't know how. But traction etc. surely is an easy way to further destabilize and stretch the plaque and the contracted tissue around it. Note that I stopped after some months when the plaques were still there(smaller though) but everything flexible enough to allow normal erections. I got rid of the last remains with only DMSO+X some months ago after using it again for 3-4 months and I nowhere used traction as much as I did first time. Only some manual + good erections + some VED

5. If you think about vitamin C and 1-3 applications a day coating the area or the whole penis then you actually get a lot that many wont get via diet. Also the amounts the supplement is told to work orally takes into consideration that it will be diluted and moved through the whole body reaching some parts in even smaller amounts. Here we focus it all on one specific part and from there it dilutes into the body.

Title: Re: DMSO+X Revisited 2019
Post by: hope794 on June 18, 2020, 07:56:21 PM
Melting bro, thanks for your reply, you've told me everything i wanted to know.

I've decided to ship back the product i've bought, it sucked, im pretty sure it was a scam. I'll buy another DMSO.
Did you buy from Amazon.de? Can you advice the product you used in PM?

Furthermore, i would like to know how many drops/ml you've applied on your penis. I've read your previous reply, but i'm really scared to make something stupid. Consider that 1ml are about 15-20 drops. How many should i put?

Thank you for your infinite patience.
Ehy, i was thinking about something. What about a Telegram group with all the guys trying DMSO? I think it can be way easier to communicate, share recipes, share experiences, results and so on. What do you guys think about it?
Title: Re: DMSO+X Revisited 2019
Post by: Tortão Pra Direita on June 18, 2020, 10:06:06 PM
Is somebody using DMSO + curcumin? I'm just waiting my curcumin to arrive.
I bought a DMSO cream (70% pharma grade DMSO + 30% aloe vera), then I'll mix it with ascorbic acid and curcumin.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 19, 2020, 06:01:51 PM
Quote from: Tortão Pra Direita on June 18, 2020, 10:06:06 PM
Is somebody using DMSO + curcumin? I'm just waiting my curcumin to arrive.
I bought a DMSO cream (70% pharma grade DMSO + 30% aloe vera), then I'll mix it with ascorbic acid and curcumin.

https://pdfs.semanticscholar.org/612c/66fc7a928e5edfe95fce473b42e8bcce8771.pdf

QuoteCurcumin has been extensively reported as a potential natural antioxidant. However, there was no data on activity comparison as well as the biological interactions of curcumin with other natural antioxidants. The aim of the present study was to investigate the antioxidant power of curcumin in comparison with three important natural antioxidants; gallic acid, ascorbic acid, and xanthone on free radical scavenging action and their combination effects on this activity. The results indicated that the activities of these compounds were dose-dependent. The 50% effective concentration (EC50) of curcumin was found to be 11 μg/mL. Curcumin showed significantly higher antioxidant activity than ascorbic acid and xanthone but less than gallic acid. Interestingly, curcumin revealed synergistic antioxidant effect when combined with gallic acid whereas the antagonistic effect occurred in curcumin combination with ascorbic acid or xanthone. These results suggest that curcumin-gallic acid combination is the potential antioxidant mixture to be used in place of the individual substance whereas using of curcumin in combination with ascorbic acid or xanthone should be avoid

Just found that first page google. Didn't investigate further. So maybe in the wrong context above but I wouldn't combine it on first look.
I would mix them seperate with the dmso+aloe.

A lot of people reported they bought aloe+dmso 70% but I was never sure if it is effective and didn't heard positive or negative about it. So it sure will have an effect, but how much I don't know compared to normal dmso mixed with X

Quote from: hope794 on June 18, 2020, 07:56:21 PM
I've decided to ship back the product i've bought, it sucked, im pretty sure it was a scam. I'll buy another DMSO.
Did you buy from Amazon.de? Can you advice the product you used in PM?

Furthermore, i would like to know how many drops/ml you've applied on your penis. I've read your previous reply, but i'm really scared to make something stupid. Consider that 1ml are about 15-20 drops. How many should i put?

Ehy, i was thinking about something. What about a Telegram group with all the guys trying DMSO? I think it can be way easier to communicate, share recipes, share experiences, results and so on. What do you guys think about it?

I bought several and all worked. Just buy the one with best rating or research the product company. Medical grade 99% is best.
It's an easy to produce product, very cheap. Makes no sense to scam and sell water or what.. If pure DMSO is in the Fridge then it will freeze above 0°C, sometimes around °6C or 10..

Then just start with one drop. Test and see if any adverse effects. If not, next time add another drop.. people react differently. Obvious if you have adverse effects you might stop immediately.
I sometimes coated my penis fully with it several times within a day or hour and nothing bad happened. A full glass 200ml of dmso+Ascorbic acid I surely did several times.

I personaly have no interest in a chat type fast moving thing. I like to write here where everyone can read it. Though I udnerstand some people want it private but I have no time to help more than a handfull people via pm or email already.
I will write soon anyway a more understandable how to, with pics to show how to mix it and then hope that someone keeps going that path, posting and updating. I read first from a guy talking about a "Doctor Thackers" like some US cowboy movie.
Best would be a doctor or pharmacists with some freedom and liberty to do it. I solved my issues and kind of have no capacity to research much more.

This was a valuable thread but with a lot of confusion and talking ideas. It needs to be consolidated boiled down
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 19, 2020, 06:04:28 PM
https://supp.ai/i/curcumin-vitamin-c/C0010467-C2349136

Discover Supplement-Drug Interactions website
Title: Re: DMSO+X Revisited 2019
Post by: Fix This on June 20, 2020, 04:47:03 AM
Hi Melting

Can I ask what type of Magnesium you use please?

And do you use a pre mixed liquid or powder/ flakes which you add to water ?

Interesting link here fellas regarding the seemingly many many uses of DMSO ( including a mention of peyronies ):

https://pforlife.com/dmso-article-2.html

Thanks again


Fix
Title: Re: DMSO+X Revisited 2019
Post by: Fix This on June 20, 2020, 04:49:10 AM
Also, does anyone know of a table / chart / list of molecular weights of all of these various compounds ?

Seems to me we could ascertain which substances are more likely to penetrate if we could check their molecular weight every time that compound comes up as a possible treatment ?

Fix
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 20, 2020, 07:33:50 PM
MgCl2 is the magnesium and I used it in 3 different forms, flakes, 'powder' and pre mixed 'Magnesium Oil'(it's not oil it just feels oily)

You can find most molecular weights easily asking google for "chemical"+"molecular weight". Sometimes it immediately shows the weight without a link

But a list would be great of all supplements that are likely to work with dmso and which are probably too big.
Title: Re: DMSO+X Revisited 2019
Post by: Fix This on June 21, 2020, 07:34:01 AM
Thanks Melting. I already have some organic epsom salts which are Magnesium Chloride rather than the Magnesium Sulphate  MCGL2 that you are using. Any difference between using these two different types of Magnesium that you're aware of ?

By the way/ I have been using DMSO a lot again this week. 3-5 times a day and at least once a day whilst using the penimsaster pro as traction. It certainly does feel as though it is benefitting and that the plaque nodule MAY be getting smaller. I may also be seeing a slight curvature improvement but will take more time to confirm

I have noticed the horzontal lines/wrinkles quite bad today across my flacid penis. The skin is looking quite red so I think I've been doing too much this week possibly, and posibly too much DMSO. I'm going to refrain from any more DMSO treatment today and possibly for a few days and instead just moisturise a lot instead. Hopefully this will return the skin to it's former state. It's not too bad , but is something that needs to be noted. The percentages that are suitable for each individual will differ as you've pointed out . So I would suggest a slow increase in the amount of DMSO used for those new to this ( or even those not new to it!)






Title: Re: DMSO+X Revisited 2019
Post by: projectpd on June 21, 2020, 12:52:21 PM
@Fix This, you wrote it the wrong way round, epsom salts is magnesium sulphate, magnesium chloride (MgCl2) is probably preferable though - less toxicity: https://www.researchgate.net/publication/7508381_Magnesium_chloride_or_magnesium_sulfate_A_genuine_question
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 21, 2020, 08:39:10 PM
If you get adverse effects due to the DMSO just dilute it. You can just add more water and it will less strong.
And if bad, like too dry or wrinkling use more lotion, whatever healthy type you can find.

Will be different for everyone. Start low and then increase time and % of DMSO. But as said, it already works with 10% but should be fine for most at 70% too.
Title: Re: DMSO+X Revisited 2019
Post by: Tortão Pra Direita on June 21, 2020, 10:50:45 PM
Quote from: melting on June 19, 2020, 06:01:51 PM
https://pdfs.semanticscholar.org/612c/66fc7a928e5edfe95fce473b42e8bcce8771.pdf

Just found that first page google. Didn't investigate further. So maybe in the wrong context above but I wouldn't combine it on first look.
I would mix them seperate with the dmso+aloe.

A lot of people reported they bought aloe+dmso 70% but I was never sure if it is effective and didn't heard positive or negative about it. So it sure will have an effect, but how much I don't know compared to normal dmso mixed with X

Man, thanks for your answer. Seems best to avoid vitamin C + curcumin combination. Better safe than sorry.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 23, 2020, 08:10:47 AM
I mean it doesn't sound like there's a danger and in any case you should always test all mixes with some drops on your arm or leg skin..
But vitamins and other supplements do react with each other creating new chemical chains. They then might weight more or dilute/change their helping properties. So I mostly used 1 supplement+DMSO. If I wanted another supplement into the regime I used another dmso+X mix in another bottle.

But some combos can be good without much direct interactions.. like vitamin C and E.. certainly worth looking into and researching.
Title: Re: DMSO+X Revisited 2019
Post by: Fix This on June 23, 2020, 09:03:07 AM
Thanks ProjectPD. Yes, you're right I wrote them the wrong way around

Anyway, I'm going to lay off all of this DMSO treatment now. I've clearly damaged my old boy with this. Despite having used it quite a bit before.I never experienced this before and now aswell as having curvature/ narrowing when erect I also have what appears to be the penis if a 100 year old man when flacid! I'm very much hoping it's not permanent

I'm going to be spending the next few weeks seeking lotions and treatment that will hopefully get rid of these lines and wrinkles, although I suspect this may be a job for a dermatologist after the lockdown.

Mistakes that I may have made to cause this may have been to not wash the mixtures off after half an hour. I think this would have been enough time for it to do it's work and could have made a difference. Aldo possibly pre mixing with the dmso in advance as Melting does. I always mixed just before application as I'd read that that is the point when the DMSO will work . This way it is harder to measure exactly how much you are using and it's 'exothermic' at this point as stated earlier in this post I think . Although I never had this problem in past useage , so I'm more inclined to think that just the sheer frequency that I have been applying ( 4-6 times a day ) is also a factor

If you're reasonably happy with where you are with your junk currently, I would tread very carefully with DMSO. I have to admit, I was pretty happy a few weeks ago with the progress I'd made over the last couple of years . But I do regret my recent use/overuse of DMSO.

I'm not doubting the success that you've had Melting. But need to let the other guys know that this can happen also

I'm pretty determined to fix things when I'm not happy about it. Unfortunately it looks as though I've created something else now that I need to fix! But fortunately where there's a will there's a way



Title: Re: DMSO+X Revisited 2019
Post by: TonySa on June 23, 2020, 09:48:57 PM
Thanks Fix, I think the caution is very important.  Safe DMSO usage takes MUCH VIGILANCE and perhaps an element of luck.  IMHO
Title: Re: DMSO+X Revisited 2019
Post by: MacMathuna on June 24, 2020, 12:40:04 PM
DMSO + Pentox?

Has anybody tried this?

It's water soluble so I guess you could just mix it the same way you'd mix DMOS + Asorbic Acid.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 25, 2020, 07:36:06 PM
Quote from: Fix This on June 23, 2020, 09:03:07 AM

Aldo possibly pre mixing with the dmso in advance as Melting does. I always mixed just before applicationas I'd read that that is the point when the DMSO will work . This way it is harder to measure exactly how much you are using and it's 'exothermic' at this point as stated earlier in this post I think . Although I never had this problem in past useage , so I'm more inclined to think that just the sheer frequency that I have been applying ( 4-6 times a day ) is also a factor

You got it! That's the problem with DIY and it sucks. Will happen again and again to people. Too bad most other treatments suck at least outside the US.. I'm sorry.

But ..who said that DMSO works only that way? ITS FALSE!
You can premix and let it sit in a bottle for days depending on the supplement and it will still have it's effect.

I mentioned several times creating the dmso+water reaction before mixing with the supplement well in advance.
If you don't do that it will react with the water in your skin. Depending on the % of DMSO applied it might happen immediately or over time.

I learned it all the hard way burning the whole skin of my dick lol Took some weeks to heal.
I suspect the wrinkly skin is a stage before that but as it's not totally destroyed like with burning it wont replace as directly and obvious.

Again, as mentioned a dozen times, observe your skin and act accordingly. When the skin is bad you can't apply dmso anymore and plaques will get hard again, at least that's what happened with mine.

I need to write one post with all of it in it cause people are not able to read a thread like this whole. That's my fault for not doing it yet.




Title: Re: DMSO+X Revisited 2019
Post by: melting on June 25, 2020, 07:38:23 PM
Quote from: MacMathuna on June 24, 2020, 12:40:04 PM
DMSO + Pentox?

Has anybody tried this?

It's water soluble so I guess you could just mix it the same way you'd mix DMOS + Asorbic Acid.
You can mix it yes. Of course if it's in pill form, pressed, then you might get a lot of filler material. Not sure if pure pentox is available..(be aware of dosage, AGAIN not personal, but some fool will use 20 pentox tablets at once).
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 26, 2020, 07:15:36 AM
Quote from: Fix This on June 23, 2020, 09:03:07 AM
I've clearly damaged my old boy with this.

Fix This! look what I found:
https://books.google.de/books?id=1mqZBgAAQBAJ&pg=PA44&lpg=PA44&dq=dmso+wrinkles+skin&source=bl&ots=gxXLLSGAXE&sig=ACfU3U0fPu2UJq4c1Cp5UO0iWnFhuja0ww&hl=de&sa=X&redir_esc=y#v=onepage&q=wrinkle&f=false (https://books.google.de/books?id=1mqZBgAAQBAJ&pg=PA44&lpg=PA44&dq=dmso+wrinkles+skin&source=bl&ots=gxXLLSGAXE&sig=ACfU3U0fPu2UJq4c1Cp5UO0iWnFhuja0ww&hl=de&sa=X&redir_esc=y#v=onepage&q=wrinkle&f=false)

It's a link to a google books excerpt of "DMSO Nature's Healer". Not sure if link works, please note attached pic below.(edit, can't attach, check here: https://imgur.com/a/h3yWQ8c (https://imgur.com/a/h3yWQ8c) )

"The skin may wrinkle and stay that way for several days". Note the book says it's directly related to the strength of solution. Obviously might also be in relation to the frequency and way of mixing right before application causing the same effect.

I'm starting to think we should recommend to start with something like 25% DMSO solutions, 1 application a day, when starting out and increase from there.

Please use some Aloe vera lotion and/or other nourishing lotions. This might take days or weeks until the skin has renewed.
Theoretically some sort of very soft peeling(there are face peelings that are not as hard has body peelings) might help speed that up.(of course be careful cause it could also aggravate)

If you had the feeling the applications help then think about restarting them with much lower dmso concentrations and pre-mix with water well in advance to have the exothermic reaction prior.

I rarely had problems with it after I burned myself.

Title: Re: DMSO+X Revisited 2019
Post by: projectpd on June 26, 2020, 02:54:15 PM
if you google it enough , you can obtain the full book (410 pages) as a pdf.   The book even mentioned using DMSO by itself for Peyronies Disease, and that the treatment takes over a year.

I haven't really found DMSO itself too irritating at eg. even 70% but mixed with iodine or ethanol, and acids it is much more so , but those are by themselves anyway.

aloe vera is great, I got some organic gel aloe vera with seaweed extract (Seven Minerals), this is certainly effective for burning/irritation. 

Interesting how long DMSO has been around, there was been a small study (n=12 )with DMSO alone for Peyronies Disease, as far back as 1969, the full text wasn't free though.

apart from DMSO as a transdermal agent, other methods are possible, as, e.g. diclofenac gel spray has been studied as penetrating to synovial fluid in the knee.
Title: Re: DMSO+X Revisited 2019
Post by: MacMathuna on June 27, 2020, 10:06:15 AM
Quote from: melting on June 25, 2020, 07:38:23 PM
You can mix it yes. Of course if it's in pill form, pressed, then you might get a lot of filler material. Not sure if pure pentox is available..(be aware of dosage, AGAIN not personal, but some fool will use 20 pentox tablets at once).

Hmmm... what do you mean my filler material? Is this just other stuff that's in the pill to carry the pentox? Is the filler a problem--could it be bad to have it carried into my skin? Or is it just that there's not enough of the actual pentox in a pill to be worth using with DMSO?

I was thinking I would just crush one or two tablets for a mix. If I'm taking the pentox anyway, it's gonna get in my bloodstream just as well by using it with DMSO as taking it orally, and some of it might reach the plaque, right?

I'm also wondering about certain drugs needing to be processed by the body before they're useful, so applying them directly to the plaque might not be helpful. Like, pentox is supposed to increase bloodflow to your extremities and that's why it might be helpful for Peyronies Disease, but it's not going to dissolve plaque right? (Or L-citrulline is supposed to help your body produce l-arginine, so applying l-citrulline directly wouldn't do anything, just as an example.)
It seems like there's certain drugs that it wouldn't help any better to have them in contact with the plaque than it would be to just take them orally. But would applying pentox topically w/ DMSO cause more of the encouraged bloodflow to be sent to your penis in particular? I don't know how this stuff works. lol
Also, when you apply a drug with DMSO, is more of it going to get into your bloodstream than if you have to process it through your stomach first when taking orally?

So many questions.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 27, 2020, 02:30:38 PM
Quote from: MacMathuna on June 27, 2020, 10:06:15 AM
Hmmm... what do you mean my filler material? Is this just other stuff that's in the pill to carry the pentox? Is the filler a problem--could it be bad to have it carried into my skin? Or is it just that there's not enough of the actual pentox in a pill to be worth using with DMSO?

I was thinking I would just crush one or two tablets for a mix. If I'm taking the pentox anyway, it's gonna get in my bloodstream just as well by using it with DMSO as taking it orally, and some of it might reach the plaque, right?

right.. obv. see amounts you take in total..

Pentox is a regulated medicament so I doubt the filler material is a big problem. But who knows,.. could be irritating skin..
It has to be in the "side effects letter" what is in it. Pentox amount also what is on the letter.

I did that with some stuff and what happens most time is that the filler material will just remain in the solution and will remain on skin after dmso shuttled in transdermal what it can(low molecular weight). So you can then wash the filler off.
I just grinded the tablets in these cases into the smallest possible powder.



QuoteI'm also wondering about certain drugs needing to be processed by the body before they're useful, so applying them directly to the plaque might not be helpful.


Very good points!

If something works on an organ that then produces something into the bloodstream, yes. No need to apply locally.
Pentox:
Pentoxifylline is used to improve blood flow in patients with circulation problems to reduce aching, cramping, and tiredness in the hands and feet. It works by decreasing the thickness (viscosity) of blood. This change allows your blood to flow more easily, especially in the small blood vessels of the hands and feet.[/quote]

I think it works right there in the blood. A 'particle attaching to blood'. Orally works, but it also is hard on the stomach for many.. anything going in transcendentally will also reach blood sooner or later anyway. So I think transdermal pentox will work too. It doesn't need the stomach itself to function.

I could guess that pentox systemically in blood might still not reach the fine blood tissue in the penis. (that's also why pde's are recommended for many cause more blood flow to the penis helping synergistically). So putting it right there it might react with thick blood in the penis.

QuoteAlso, when you apply a drug with DMSO, is more of it going to get into your bloodstream than if you have to process it through your stomach first when taking orally?

Theoretically if the dmso manages to shuttle it all in then you will get more of the drug than orally cause the stomach is not perfect with taking nutrients.

Title: Re: DMSO+X Revisited 2019
Post by: Holistic on June 28, 2020, 12:49:33 PM
Quote from: melting on October 21, 2019, 06:54:42 PM

The biggest problem with the DMSO+X(like Ascorbic Acid, magnesium or Vit e) was that it's runny.
With Thackers Formula the biggest problem was that it didn't mix.

I got all the stuff DMSO, Castor oil(cold pressed), vit c, magnesium etc. and now will work on finding a way to get an easy usable solution/creme/wax/lotion to apply the good ingredients without hassle.

Hey melting,

I think im doing this quote thing right....anyways, I have seen a couple posts where you mention Vit C mixed in with your DMSO. Just for clarification, when you say pure Vit C powder, do you mean vit C crystals or do you actually mean powder? If it actually is powder (like consistency of flour), what brand do you use?

Because I take Vit C crystals from the company "Now". I actually tried dissolving it in the castor oil but it was still in crystal form. Wasnt sure if the crystals undissolved are still effective or not. I guess not since theyre still on the skin surface from an over night application
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on June 28, 2020, 12:53:56 PM
Quote from: melting on October 21, 2019, 11:00:37 PM
TO THICKEN THE SOLUTION

Would be great to have it more gel like.

In case I might have missed a post somewhere (since there are hundreds of places to go looking for specific info even with the search bar), has anyone considered the gel that is used for therapeutic ultrasound? Seeing as it is used as a conductor on the skin and can be mixed with biofreeze or any medication when using ultrasound...I wonder if that can be used in the DMSO application to make it more gel like....Thinking out loud.
Title: Re: DMSO+X Revisited 2019
Post by: MacMathuna on June 28, 2020, 01:46:28 PM
Melting,

Thank you for your thorough reply.

Quote from: melting link=topic=12587.msg123987#msg123987 date=1593282638


i].

I think it works right there in the blood. A 'particle attaching to blood'. Orally works, but it also is hard on the stomach for many.. anything going in transcendentally will also reach blood sooner or later anyway. So I think transdermal pentox will work too. It doesn't need the stomach itself to function.

I could guess that pentox systemically in blood might still not reach the fine blood tissue in the penis. (that's also why pde's are recommended for many cause more blood flow to the penis helping synergistically). So putting it right there it might react with thick blood in the penis.



Ok, so I'm hearing that pentoxiphylline reacts directly with the blood, rather than being processed by the body and then being turned into something else (like how l-citrulline helps the body produce l-arginine).

I guess I will give DMSO+Pentox a try then.



Title: Re: DMSO+X Revisited 2019
Post by: hope794 on June 28, 2020, 04:32:44 PM
i'll try again to make this question:

How much milliliters or drops of DMSO+X do you apply every time on the penis?
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 28, 2020, 05:23:09 PM
Quote from: Holistic on June 28, 2020, 12:49:33 PM
Just for clarification, when you say pure Vit C powder, do you mean vit C crystals or do you actually mean powder?

Because I take Vit C crystals from the company "Now". I actually tried dissolving it in the castor oil but it was still in crystal form. Wasnt sure if the crystals undissolved are still effective or not. I guess not since theyre still on the skin surface from an over night application


100 % Ascorbic Acid (Vit. C) . It's hard crystals I guess and your product seems ok albeit a bit expensive? I pay 2.20 $ for 100g.. maybe one of the few good things in germany is that vitamin C is available dirt cheap in every grocery store. I had people in some countries not having it available in a shop.

It wont dissolve in oils so it didn't do anything and just sit on your skin ;). It's water soluble (easily and readily). You have to put in water until you can't dissolve more(saturated). If you want to combine it with oil you need an emulsifier added that "connects" the water and oil. That's basically how many lotions etc. are made and what I presented in this thread. For example Xanthan or lecithin..

Vitamin E for example is an oil soluble vitamin (https://www.healthline.com/nutrition/fat-soluble-vitamins) which wont dissolve in water and needs oil.
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 28, 2020, 05:24:59 PM
Quote from: Holistic on June 28, 2020, 12:53:56 PM
has anyone considered the gel that is used for therapeutic ultrasound?

Would love to have more info about it.. ingredients etc. then we can see if there are any possible issues with DMSO. But if its used on skin with ultrasound good chance it's ok. Then we need to see if we can buy it and mix it with dmso..
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 28, 2020, 05:28:45 PM
Quote from: hope794 on June 28, 2020, 04:32:44 PM
i'll try again to make this question:

How much milliliters or drops of DMSO+X do you apply every time on the penis?

Start with just some drops and see how skin etc. reacts. 
But I basically coat the whole penis with it and then sometimes I did that several times an hour. (after getting used to it)

You have to be aware of how much of the supplement-X you put into your mix. With vitaminC-X for example I can apply bottle after bottle without any worry lol. But for example iodine-X you see what the maximum dosage is and how much is in your bottle. I never worried much about it though cause the amounts are mostly less than I would've taken orally.
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on June 28, 2020, 07:26:38 PM
Quote from: melting on June 28, 2020, 05:24:59 PM
Would love to have more info about it.. ingredients etc.

Tomorrow, Ill check out what kind of gel we use in our clinic for physical therapy. and try to find this message. I see once I look at the new messages, they disappear and I cant find them anymore.
Title: Re: DMSO+X Revisited 2019
Post by: hope794 on June 29, 2020, 09:26:47 AM
Quote from: melting on June 28, 2020, 05:28:45 PM
Start with just some drops and see how skin etc. reacts. 
But I basically coat the whole penis with it and then sometimes I did that several times an hour. (after getting used to it)

You have to be aware of how much of the supplement-X you put into your mix. With vitaminC-X for example I can apply bottle after bottle without any worry lol. But for example iodine-X you see what the maximum dosage is and how much is in your bottle. I never worried much about it though cause the amounts are mostly less than I would've taken orally.

Thanks!

I've started the experiment. DMSO + Vit. C 3 times a day. Let's see how it goes.

Very strange: 99.99% pure DMSO, without water, doesnt do anything to my skin. I thought it was a fake DMSO, so i ordered another. Same non-reaction. Furthermore, i have put both of them in the fridge (not freezer!) and, while the water didnt get into ice, the DMSO both turned into ice at 6°. So it's DMSO.

Really strange. I prepared a 70% DMSO and 30% water with some castor oil and Vit. C. I addded Vit. C until i didnt see anymore it diluted.

Furthermore, i didnt feel anything when applying DMSO. I am scared it won't work for me, dunno why. Maybe i'm doing something wrong?
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on June 29, 2020, 09:33:31 AM
Quote from: hope794 on June 29, 2020, 09:26:47 AM

Really strange. I prepared a 70% DMSO and 30% water with some castor oil and Vit. C. I addded Vit. C until i didnt see anymore it diluted.

Hey Hope794,

Any chance youre able to convert the percentages into measurements? even if its tablespoons. Also what size tincture bottle are you mixing in, or is it a small bowl?
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 29, 2020, 09:58:25 AM
hope794, I rarely felt anything during application. Should be ok. You will surely see some of the mix "going inside" and not everything remaining on the skin(some will..)

People seem to react very different to DMSO and it's %. I guess maybe very light skin types have more problems.. similar to sun exposure..
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on June 29, 2020, 10:48:06 AM
Quote from: melting on June 29, 2020, 09:58:25 AM
I rarely felt anything during application. Should be ok. You will surely see some of the mix "going inside" and not

I actually tried this morning, castor oil, iodine and a bit of (best i could) dissolved Vit C in water, then put the C paste on my skin with iodine and castor. I know you mentioned an emulcifier was needed but the crystals still seemed solid and on the skin. hopefully some were able to go through. But i Had it on for maybe 30 min and started to feel discomfort in the plaque. Wasnt sure if it was residual strain from sex a couple days ago from being erect or the application of what I did. I wiped it off and put warm compress on it for 5 min and it felt better after. Not sure if it did much. Castor oil Im told takes months before noticible effects to the plaque (if calcified, I guess).

Im off to work but will look into the ultrasound gel and try to find the thread where it was discussed as a base to make a solution more gel like
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 29, 2020, 12:09:46 PM
Vitamin C should readily dissolve in water
https://en.wikipedia.org/wiki/Chemistry_of_ascorbic_acid

QuoteSolubility in water
   330 g/L
Warm(never hot cause it denatures V-C and also why in my recipe I pre-mix dmso with water to also not heat the VC) water and some shaking stirring. Everything that doesn't dissolve is too much for the amount of water(add more water). Crystals on skin will be "useless".
Did you have it on with dmso? If you had dissolved VC + DMSO then the chances are high some reached the plaque. If without dmso chances are very low.
If you had it with dmso then 30 minutes are not needed. DMSO will have gone through skin within 1second to ~10minutes.

I noticed "movement" and stuff in the plaque all the time when deep into a dmso+X routine. When it changes form or calcification dissolves or "gets off" then the healty tissue might get new "attach-points"/rubbing against the plaque or nerves and blood cells move. Not necessarily bad.

With DMSO+X used a lot I often noticed changes to the state of the plaque within days and I also noticed the plaque getting hard again after stopping within days.(I think the body calcifies the plaque to "cool down" the inflammed fibroid and "excluding"/"isolating" it from the healthy body)

THAT is how I knew DMSO+X(thackers formula back then) works! It somewhat softened but no big changes to the condition but then within days it hardened again noticeably, that's when I knew there was a significant impact and did go all in for many months applying(+traction etc.) and observing the impact on erection lessening more and more.

also mentioned before.. VitC + DMSO on nails will stain the nails yellow as the VC gets trapped in it.
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on June 29, 2020, 09:59:15 PM
See....this kind of info is gold. i tried to dissolve C in cold water filtered by Zerowater so it has 000 ppm. Ill try again with warm water.

I did not use DMSO, I have yet to purchase any after ive gathered the info i need from here to start my kit. especially getting the right amount and not have anything calcify after stopping using it. I wonder if it hasnt calcified yet, that if using the DMSO and stopping will cause the calcification if it wasnt going to do so on its own..could that even be possible?

So far i have been using castor oil as the method to deliver iodine into my plaque
Title: Re: DMSO+X Revisited 2019
Post by: melting on June 30, 2020, 07:28:34 AM
No, I don't see how it could calcify it.
Iodine on it's own can penetrate the skin barrier. Could be castor oil clogs the skin but idk maybe it works transdermally too? With Iodine you might see how it seeps into the skin on its own.
Using vitamin C without a transdermal agent seems rather futile. It might penetrate some layers and if the faulty tissue is very near the skin it might work some but most probably wont get deep enough and with high probability wont penetrate faulty tissue itself.
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on June 30, 2020, 09:05:52 PM
honestly, i dont notice much absorption. I put one drop that is about 640 mcg. and watch it for a few seconds and tilt the skin so the liquad moves but i dont see anything soaking in. after a min, i use my finger to rub it around the area and gently blow on it to dry it up. then i add the castor oil and put a cotton swab over it and wrap it up and go to bed. I thoguht the castro oil helps deliver the iodine deeper? I thought I read somewhere that it helps deliver but I coud be wrong and it has been a placebo this whole time lol.
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on June 30, 2020, 09:28:41 PM
Quote from: melting on June 26, 2020, 07:15:36 AM
Fix This! look what I found:

Hell yeah, I was able to find this book as an audio on my app. Deff going to crush this book. Thanks for the post!!
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on June 30, 2020, 09:32:45 PM
Quote from: melting on June 26, 2020, 07:15:36 AM
Fix This! look what I found:

If anyone is looking for this book for free, it is on Hoopla which is a free app download and give you access to a ton of books. all you need is an active library card. Ive save about 1k /year on audio books
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on June 30, 2020, 09:50:36 PM
Quote from: melting on June 29, 2020, 12:09:46 PM


well this sucks, I am unable to load the pictures into this chat.

Gel 1:

Sonigel: transmission gel for therapeutic and diagnostic ultrasound. Sonicator 740.

Its manufactured by mettler electronics corp.

Gel 2:

Conductor transmission gel: Aqueous coupling agent for ultrasound and electromedical procedures. Non-allergenic. "for external use only. use on intact skin only. not intended for surgical use. not for use with defibrillators."

Manufactured by chattanooga

----------------------------------------

There is a bar code on the gel 2 with numbers if that is of any use. But other than that, there weren't any ingredients listed. Gel 2 has a bluish tinge to it. Gel 1 is clear.
Title: Re: DMSO+X Revisited 2019
Post by: projectpd on July 01, 2020, 04:13:31 AM
they are probably made from fairly non toxic stuff but even so would want to know whats in it. google suggested propylene glycol, but here's one you can see the ingredients in the pic , https://www.naturalliving.co.uk/acatalog/eureka-eu-eusg0300-ultrasound-gel-250ml-size-250ml.html#SID=6697.  the purpose is simply to exclude air though so any thick gel should work.
Title: Re: DMSO+X Revisited 2019
Post by: MacMathuna on July 01, 2020, 10:21:06 AM
Since not a lot of people with Peyronies Disease are complaining about loss of sensation, I'm figuring that I may have some nerve damage in my penis.

I've skimmed some studies suggesting that DMSO on its own may be helpful in peripheral nerve regeneration.
I'm just wondering about DMSO+ mixes for peripheral nerve regeneration.

Wonder how any of this would mix with DMSO:
Hyaluronic acid, Tacrolimus, Cyclosporin A, Melatonin, Methylprednisolone, Vitamin B12, Riluzole, 4‐Aminopyridine, Verapamil.

Title: Re: DMSO+X Revisited 2019
Post by: melting on July 01, 2020, 03:54:39 PM
Sonigel:
QuoteUV purified water, triethanolamine, carbomer, edta disodium, propelyne glycol, diazolidinyl urea, iodopropynyl butylcarbamate 
(https://www.trtllc.com/store/p10/Sonigel_5_Liter_Jug_.html#/)

Mostly it seems compounds with a rather small molecular weight, if I understand correctly, which could mean they get into skin with dmso. That said also most of them seem fine but with dmso I don't know.

Sure would be nice to have a gel like dmso application. I'm sure some more research one could find how to make a dmso gel.. Need a pharmacist on board ;)
If someone tries, do it on the arm with low amounts...

Title: Re: DMSO+X Revisited 2019
Post by: melting on July 01, 2020, 04:00:01 PM
Quote from: MacMathuna on July 01, 2020, 10:21:06 AM
Wonder how any of this would mix with DMSO:
Hyaluronic acid, Tacrolimus, Cyclosporin A, Melatonin, Methylprednisolone, Vitamin B12, Riluzole, 4‐Aminopyridine, Verapamil.

You need to know the molecular weight. (not more than ~1000 g/mol)
You need to know the solubility. Water or oil... (and then you either need to mix it with water or oil, before mixing it with dmso+water)

for example vitamin b12 with 1356.4 g/mol might be too much... Also obviously be aware of side effects toxicity etc. I think that Melatonin can have a lot of side effects.

But yeah surely might make sense to add into the peyronies regime if nerve problems are part of it, in whatever form.
Title: Re: DMSO+X Revisited 2019
Post by: hope794 on July 02, 2020, 08:14:00 AM
Hyaluronic Acid seems to be lacking in Peyronies Disease's patient: a study found that in the patients with Peyronies Disease, there is nearly 0% HA inside the harmed tunica albuginea. But i think that its molecular weight it's too big.

NEWS: I began since 4 days the DMSO+X experiment. I've started with DMSO+Vit C, just like melting suggested. I'm applying about 1mL each time, 3 times per day. After 10 minutes, i wash away the DMSO from the penis.

In the next days i'll give my penis to the science: i'll try a dangerous experiment. I've found some KETORALAC vials, and i will mix them with DMSO. Ketoralac is a REALLY POWERFUL antinflammatory and anti-pain drug. Doctors prescribe it after a surgery, to bear with the pain. It is really powerful and dangerous, if you inject vials, you can't use it more than 5 days, since it can cause systemic issues to the body. But the molecular weight is about 300 g/mol, so i will transport via DMSO.

I'll update.

P.S. = What about a DMSO+X Telegram group? So we can chat daily about the experiments.
Title: Re: DMSO+X Revisited 2019
Post by: MacMathuna on July 02, 2020, 03:09:51 PM
Quote from: hope794 on July 02, 2020, 08:14:00 AM
Hyaluronic Acid seems to be lacking in Peyronies Disease's patient: a study found that in the patients with Peyronies Disease, there is nearly 0% HA inside the harmed tunica albuginea. But i think that its molecular weight it's too big.


Yes, the Molecular weight is too high. I'm unsure about hyaluronic acid. It's supposed to prevent collagen loss, which... I'm wondering if that would keep peyronie's plaque from reducing.

But, there are studies of HA injections being somewhat helpful with peyronie's disease. And it's sometimes used to fade scars, so that has to be good, right?  I don't understand how collagen works guh.
Title: Re: DMSO+X Revisited 2019
Post by: melting on July 02, 2020, 03:27:52 PM
edit: Mac, 846.8 g/mol might still be ok.. but yeah it's towards the higher ceiling .. idk for sure..

Quote from: hope794 on July 02, 2020, 08:14:00 AM
Hyaluronic Acid seems to be lacking in Peyronies Disease's patient: a study found that in the patients with Peyronies Disease, there is nearly 0% HA inside the harmed tunica albuginea. But i think that its molecular weight it's too big.

846.8 g/mol could be good to go!
Insulin for example is impossible: 5808 g/mol
Ascorbic acid: 176,12 g/mol (one of the lowest weights from our supplements)

Interesting point.. You can post links or copy paste raw stuff it into this thread if you find something that might help..
I personally am not as motivated right now to dig very deep. I like to work with what I know about this topic right now.
I hope someone takes this whole topic further soon.

Search for "X+ scars" "X+fibrosis" one can find a lot of info that (possibly)can be 'translated' to peyronies. Cause penis specific stuff is rare.
hyaluronic acid sounds very good and is often in cremes and lotions too.

QuoteStudies show that hyaluronic acid works well as an anti-aging dermal filler. It also works very well as a treatment for acne scars. In a 2013 study, researchers found that patients with acne scars experienced an "immediate visual improvement" after getting hyaluronic acid injections.


QuoteIn the next days i'll give my penis to the science: i'll try a dangerous experiment. I've found some KETORALAC vials, and i will mix them with DMSO. Ketoralac is a REALLY POWERFUL antinflammatory and anti-pain drug. Doctors prescribe it after a surgery, to bear with the pain. It is really powerful and dangerous, if you inject vials, you can't use it more than 5 days, since it can cause systemic issues to the body. But the molecular weight is about 300 g/mol, so i will transport via DMSO.

I'll update.

Honestly that sounds awful! Has a lot of side effects. But if you know the risks and sideffects you can obviously do what you want..

Just note that peyronies mitigation is in most cases a marathon and steady wins that. If Ketoralac doesn't work with one application then you might need many more which will increase the side effect %.
Most of what we do here is still kind of bro science winging it.(that's why I hope a pharmacist joins us..)

Still interesting.. lol
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on July 02, 2020, 10:23:32 PM
Quote from: melting on June 19, 2020, 06:01:51 PM

This was a valuable thread but with a lot of confusion and talking ideas. It needs to be consolidated boiled down

I agree. Im starting to get lost in all these other ideas. Im listening to that DMSO book now and it is good. Im trying to hunt down the posts you have of your exact steps and ingredients so I can try. I believe DMSO, iodine and C should be most effective. just need to know the ins and outs like why not to have the solution touch metal and plastic etc. I feel almost overwhelmed by all these other suggestions.
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on July 03, 2020, 07:38:11 AM
Hey guys,

I would recommend getting a copy of DMSO: Natures healer, that Melting came across. I'm listening to it now and it is really informative and demystifying for this compound.

I just came across a part in the book that claims DMSO 50-80% applied 2-3 times a day will help get rid of keloids. It was a general statement. But I'm about 2 hrs in out of 11hrs of the total book and I'm really liking it.

It discusses also how DMSO works by acting like water going through the skin and the blood brain barrier for other conditions etc. It discusses its molecular weight(which is beyond my grasp. I just look for functional application).

Worth checking it out
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on July 03, 2020, 07:42:48 PM
Sixteen of DMSO's advantages and wide ranges in use against organic disease:

1 - Blocks pain by interrupting C-fibers
2 - anti-inflammatory
3 - bact/fung/viralstatic
4 - transports pharmaceuticals across membranes
5 - reduces platelet thrombi in blood vessels
6 - inhibits calcium to reduce workload of the heart
7 - acts as a tranq when rubbed into the skin
8 - enhances anti-fungel and anti bacterial agents when combined.
9 - Vasodilator
10 - inhibits release of coleresterase (sp)
11 - softens collagen by a cross linking effect
12 - scavenges hydroxel free radicals
13 - stimulates various types of immunity
14 - diuretic
15 - brings out interferon
16 - stimulates healing in wounds

Listed from, DMSO: Natures healer book
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on July 03, 2020, 08:02:14 PM
Quote from: melting on July 01, 2020, 03:54:39 PM

Sure would be nice to have a gel like dmso application.
If someone tries, do it on the arm with low amounts...

This one is a gel with 70/30 of DMSO/distilled water.

https://www.amazon.com/DMSO-70-Gel-Unfragranced-Ounce/dp/B0014AU8MK -

This one is non-diluted pharmaceutical grade.

https://www.amazon.com/DMSO-99-995-Diluted-Dimethyl-Sulfoxide/dp/B01L2FQAPU/ref=pd_lpo_121_t_2/130-6945731-8422050?_encoding=UTF8&pd_rd_i=B01L2FQAPU&pd_rd_r=e526f452-f0ff-44ff-a9de-d64de7faba8c&pd_rd_w=VHBPX&pd_rd_wg=1CyAY&pf_rd_p=7b36d496-f366-4631-94d3-61b87b52511b&pf_rd_r=SXZJFXQC4QRV22FWKF2X&psc=1&refRID=SXZJFXQC4QRV22FWKF2X

Would this be more of what youre talking about? Also, if the product is labeled as 70/30 already. At 99%, would the product still need to be cut with distilled water? And is the product distribution of 70/30 the same as what youre talking about with your solution by cutting DMSO with water when you do it yourself? If the company does the water cutting, I would think that would take out half the work...or do you think it is not as effective or doesnt even matter? Im asking bc i wouldnt know how to measure a 70/30 ratio with no standard measurements with pure DMSO and distilled water.
Title: Re: DMSO+X Revisited 2019
Post by: melting on July 03, 2020, 10:24:28 PM
Quote from: Holistic on July 02, 2020, 10:23:32 PM
I believe DMSO, iodine and C should be most effective. just need to know the ins and outs like why not to have the solution touch metal and plastic etc. I feel almost overwhelmed by all these other suggestions.
I suggest to start with 1 and get used to it and then add other mixes. The basic (Water+DMSO)+(Water+Ascorbic acid) is easy and cheap (of course read the instructions and risk mentioned. you can search top right corner this thread with "ascorbic")
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on July 05, 2020, 10:05:36 PM
Quote from: melting on November 13, 2019, 08:14:11 PM

-2 Brown glasses with a glass eye dropper(pharmacy) or another cap that isn't made of harmful plastics(https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/Product_Information_Sheet/d2650pis.pdf read - compatibility )

Just to be clear, when you say brown glasses, do you mean like this: https://www.amazon.com/Boston-Complimentary-Perfume-Calibrated-Dropper/dp/B073VD1421/ref=sr_1_46?dchild=1&keywords=4oz%2Bamber%2Bglass%2Bbottle%2Bwith%2Bglass%2Bdropper&qid=1594000112&sr=8-46&th=1

Also, I read the sigma sheet about the compatibility and incompatibility. I honestly have no clue how one would find if the plastic cap is harmful or not lol. I posted a question to the manufacturer... All those words are foreign to me except PVC.

Do you have a weblink or name brand of the glass bottle you used specifically? That would help since this method seems to require exact sterility and precision for handling. Otherwise id just by a big glass and mix it in. but since youre saying theres potentional issues with plastic...that changes things.

When you say mixer...all i can picture is the blender my mom uses to bake. so Im unsure what you mean. do you have an example of a mixer you are referring to? like a metalic mixer someone uses to froth milk for espressos or something more specific?

I apologize for my needing to clear up wording, I just want to make sure im on the same page.

Title: Re: DMSO+X Revisited 2019
Post by: melting on July 06, 2020, 07:57:56 PM
Yes, pharmacy type brown bottle. I bought mine in pharmacy's around town. Never had an issue.
Btw. plastics that react immediately with DMSO they will get "cloudy" or change color rather fast.

I use a similar mixer: https://static.mueller.de/5540139056-PV-0/pdmain/bosch-stabmixer-set-msm6b150.jpg
"Stabmixer" in german. I never let it get in contact with dmso only to premix the "X" and water/oil and emulsifiers etc.

I warn to use any plastic or metal but in reality some plastic is no issue with dmso.
It's just that someone will use some very poisonous plastics with DMSO and blame me lol

For example: https://en.wikipedia.org/wiki/Polypropylene is compatible with dmso.. "PP"
This dropper is "PP": https://www.berlinpackaging.com/20-400-black-pp-plastic-graduated-dropper-cap-with-glass-pipette-x775grad/
I think most in pharmaceutical grade stuff is that kind cause other chemicals will react with the PVC type non-compatible too.
So I probably would not use some crap from China...

DMSO is often delivered in HDPE plastic bottles.

from the Link:

QuoteThe compatibility of DMSO with various materials is listed below: • Compatible:  LDPE, HDPE, polypropylene, PPCO (polypropylene copolymer), polymethylpentene, nylon, teflon FEP •   
Moderately compatible:  polystyrene, ECTFE/ETFE •   
Incompatible:  polysulfone, flexible and rigid PVC tubing, polycarbonate
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on July 07, 2020, 10:07:12 AM
Fantastic. I'll look more into it after work. Yeah I know what you mean about people not taking responsibility, I encounter it every day with some people. I'm just looking to get as concise as possible to get started. I'm pretty pumped to try it. I finally got C to dissolve so I've been applying C water and iodine on my shaft for now. Not sure if that is doing much but it's better than nothing while taking supps.
Title: Re: DMSO+X Revisited 2019
Post by: theone45 on July 07, 2020, 01:04:28 PM
I've just started trying to use DMSO and am trying to get my own mix going.

Right now I'm just using Vitamin E, 70% DMSO, Aloe Vera Gel, and MSM.

Bought a liquid CoQ10 to add to the mix.

I don't see see anything in the ingredient list that I should be wary of, but wanted to check.

The mix consists of water; matrixyl 3000, ubiquinone, glycerin, hyaluronic acid, vitamin e, aloe barbadensis, benzylalcohol DHA.

I was trying to get a mix with as few chemicals as possible to limit side effects, and applying ubiquinone directly to the scar with dmso seems like a better idea than the oral version.
Title: Re: DMSO+X Revisited 2019
Post by: melting on July 07, 2020, 04:24:37 PM
Quote from: theone45 on July 07, 2020, 01:04:28 PM
The mix consists of water; matrixyl 3000, ubiquinone, glycerin, hyaluronic acid, vitamin e, aloe barbadensis, benzylalcohol DHA.

I was trying to get a mix with as few chemicals as possible to limit side effects, and applying ubiquinone directly to the scar with dmso seems like a better idea than the oral version.

Sounds fine on first look...
Ubi has Molar weight: 863.34 g/mol which is probably good for trans-dermal delivery.
I think using oral and transdermal can be effective.., maybe at different times, watching out for how much you take altogether.
Title: Re: DMSO+X Revisited 2019
Post by: projectpd on July 07, 2020, 04:48:47 PM
@theone45 interesting ingredients list. I will look them up.  How did you discover them? I would say watch out for vit E. it has a history of neutral or even negative results in studies after its discovery. check out my posts or Barrie Tan.
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on July 07, 2020, 05:35:22 PM
Quote from: melting on July 06, 2020, 07:57:56 PM
Yes, pharmacy type brown bottle. I bought mine in pharmacy's around town.




For example: https://en.wikipedia.org/wiki/Polypropylene is compatible with dmso.. "PP"
This dropper is "PP": https://www.berlinpackaging.com/20-400-black-pp-plastic-graduated-dropper-cap-with-glass-pipette-x775grad/

And your pharmacy had 200ml bottles around? Lol I'll check mine around town. 7 oz is huge. I may have to order from a packaging place like you did. And your dropper was separate, correct? Bc it looks like I'll have to order a7-8 oz bottle with a PP cap and buy a dropper separately. I feel like I'm on a treasure hunt lol
Title: Re: DMSO+X Revisited 2019
Post by: melting on July 08, 2020, 07:14:10 AM
We lack a lot of stuff in germany but chemicals, vitamins and such glasses including glass eye droppers etc. are all easily available in pharmacy and Ascorbic Acid is sold in the grocery store.
The pharmacy can basically order anything and it's there the next day. (costs a lot more than buying online though)

Shouldn't be a problem in the US to find what you need though, getting delivered.. one search on google..
A much bigger problem for other countries in the EU or South America where it's sometimes hard to find plain Vitamin C powder offline and online.
Title: Re: DMSO+X Revisited 2019
Post by: melting on July 09, 2020, 07:27:47 AM
So how do we create a gel that is infused with DMSO and X?
A gel would be even better than what was tried in this thread.
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on July 09, 2020, 07:42:55 AM
At some point when I get started in my process I can mix w the ultrasound gel and see how that holds. The two brands we carry seem to be safe but I'll look more into specific ingredients.

Also, when you finish a bottle. In between replenishing your mixes...how do you go about cleaning things out, just regular soap and water or any specific cleaning solution?
Title: Re: DMSO+X Revisited 2019
Post by: melting on July 09, 2020, 08:00:01 AM
I always flush it in the end with water to clean any chemicals..
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on July 09, 2020, 08:31:40 AM
So you dont use any soap or anything, just rinse out with plain water? Even the glass dropper?


I feel my questions are taking away from the main purpose of the thread but I dont know where the appropriate thread would be to ask.
Title: Re: DMSO+X Revisited 2019
Post by: melting on July 09, 2020, 08:47:29 PM
You can use soap and then make sure no soap is on it before using dmso again.

Title: Re: DMSO+X Revisited 2019
Post by: Holistic on July 10, 2020, 09:37:11 PM
ylang-ylang oil

Density 0.911 g/mL at 25 °C(lit.)

Use: enhances blood flow
Title: Re: DMSO+X Revisited 2019
Post by: DarrenBent on July 12, 2020, 04:10:13 PM
Apologies if this has been covered already - so much info here!

What are people's experiences/researches/thoughts on water soluble POTABA powder instead of (or in addition to) Vitamin C in the DMSO solution?

I'm currently taking 12g a day orally so have crap tons of the stuff.

Title: Re: DMSO+X Revisited 2019
Post by: hope794 on July 12, 2020, 06:53:53 PM
UPDATE: I am using DMSO 70% + a little bit of water (for the heat reaction) and castor  oil. Furthermore, i've added 150mg Diclofenac (In italy, the name is "Voltaren fiale -75mg/3mL).

What can i say? It's a good anti-inflammatory, and i can advice it to cope with inflammation sensation and pain.

I apply 1 mL of DMSO + Diclofenac, 2 times a day
and 1mL of DMSO + Vit. C, 1 times a day.

Nevertheless, i'm starting to think that melting had success because he said he applied DMSO+X like 3-20 times a day, let's say an average of 8-9 times per day. It's a lot!
Scaring as it seem, i'm starting to think that this guy had success because of this. 3 times a day look like more a "mantaining" rather than an "aggressive attack cure". You know what i mean?

The crap thing is that it takes about 15mins for DMSO to be absorbed. Multiply it for 8 times a day it's 2 long hours in the bathroom. WTF. Not everyone got so much time to do so everyday if you work or need some privacy :( . It will be an issue to do that. I'll raise to 6 times a day.

However, my next program will be:

DMSO 60% + Diclofenac (225mg) , 3 times a day
DMSO 60% + Verapamil (20mg) (In Italy, the name is "Isoptin fiale") 2 times a day
DMSO 80% + ALCAR until total diluition, 1 time a day

I'll update..  What do you think about it? May it work? Please notice that i downregulated the % of DMSO since these molecules have <300 g/mol weight.
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on July 12, 2020, 09:44:01 PM
Hope, if you're following melting protocol he also included traction and VED.  Combination treatments show better progress than single modalities.  Since you have less strong erections than before, I'd also consider adding low dose nightly cialis (2.5-5mg).  It helps with erections and remodeling plaque to healthy tissue.
Title: Re: DMSO+X Revisited 2019
Post by: melting on July 13, 2020, 11:37:45 AM
Quote from: woodstorm on July 12, 2020, 04:10:13 PM
What are people's experiences/researches/thoughts on water soluble POTABA powder instead of (or in addition to) Vitamin C in the DMSO solution?

I used it for some time, just Paba(almost same as potaba), along with other mixes. I didn't mix it with other supplements.
You can search the thread top right which gives this: ;)
https://www.peyroniesforum.net/index.php/topic,12587.msg115772/topicseen.html#msg115772 (https://www.peyroniesforum.net/index.php/topic,12587.msg115772/topicseen.html#msg115772)
Title: Re: DMSO+X Revisited 2019
Post by: melting on July 13, 2020, 11:51:05 AM
Quote from: hope794 on July 12, 2020, 06:53:53 PM

Nevertheless, i'm starting to think that melting had success because he said he applied DMSO+X like 3-20 times a day, let's say an average of 8-9 times per day. It's a lot!
Scaring as it seem, i'm starting to think that this guy had success because of this. 3 times a day look like more a "mantaining" rather than an "aggressive attack cure". You know what i mean?

The crap thing is that it takes about 15mins for DMSO to be absorbed. Multiply it for 8 times a day it's 2 long hours in the bathroom. WTF. Not everyone got so much time to do so everyday if you work or need some privacy :( . It will be an issue to do that. I'll raise to 6 times a day.


Most days I probably used it ~ 3-5x too.
But on some days, when I was home alone, watching TV or on the PC, I would just sit on a clean white towel and apply it all day long over and over.
Of course if you have to use everytime the bathroom then this can turn into a very cumbersome exercise.

The whole purpose of this dmso thread was to find a mix that you can apply without it dripping. As I had no big issues anymore I neither had the motivation to sit around with a wet drippy penis.
So when you use the DMSO+X + Emulsifier + oil then it will be easier as it's more like a creme/lotion..

The original "Thackers Formula"(you can search and find a lot about it) was a "wrap" around the penis which one could "carry around"(the penis). If done right possible under clothes too. Still rather messy.

I did the same with the traction and VED.. Mostly 1-4 hours a day but if I had time I used it up to 16 hours.
In any case, it will take time. I noticed improvements after a few weeks this way but big improvements only months in. (I know it was related to the protocol cause whenever I stopped for a few days it got worse again.)

If you feel like your tissue is inflamed then the diclofenac is proabably a good idea. I wish you good patience in this, it's a marathon not sprint!
The reason why I recommend daily(while taking care of the skin! If skin is bad you have to pause) is cause I could feel the plaques getting hard fast after stopping. Within days.
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on July 13, 2020, 03:41:11 PM
Just FYI diclofenac gel is absorbable on its own.
Title: Re: DMSO+X Revisited 2019
Post by: melting on July 14, 2020, 08:53:35 PM
Quote from: TonySa on July 13, 2020, 03:41:11 PM
diclofenac gel is absorbable on its own.

If kept on the skin for hours or applied very often.. ineffective to penetrate into the plaques especially when deep in the penis tissue.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771745/

In vitro..
Title: Re: DMSO+X Revisited 2019
Post by: melting on July 14, 2020, 09:34:29 PM
I never had any commercial interests in helping with peyronies and never will have.
Everything I know is available for free and was told in my posts(albeit often quiet long and hard to read I guess..), and the means I used were mostly cheap to buy.
My motivation was to help people who suffered from this after going through it for years myself. 

That feeling seeing my penis "destroyed", being diagnosed and not helped by the urologists in Germany(socialized government medicine sucks! DONT do it America!) was devastating and I will never forget it and creates empathy for anyone suffering of it.
Also many young people have huge problems with their pelvic floor which creates ED. (due to unhealthy masturbation habits and stress) which many who ask for help here(sometimes along with Peyronies Disease cause it makes Peyronies Disease worse and sometimes only PF problems) suffer from. I think I understand that problem quiet good by now.(relax, balance and strengthen the PF..)

After the first time depressed and hopeless I'm glad I found this forum and get help from a lot of people. Thanks to everyone making this possible(incl. the admins)
Being forced to not have access to most of what the Americans on this board have in means to combat Peyronies Disease I focused on DIY solving my peyronies and dedicate a lot of time to it and succeeded. Great that this was possible here, many other forums would never allow any alternatives discussed.
Sadly I think my time on this forum is coming to an end for various reasons. Right now I'm "watched". Seeing others being "muted" it might happen to me too soon. What I always loved with Americans was Free Speech being number 1. Ironically that seems to deteriorate! I can be reached through peyronies_eu @gmx.net (it could be this post gets deleted.. so please share the email with others). I have family to care for so it's possible it takes some days or weeks to answer. All that's necessary to get improvements with Peyronies Disease even if you're in a bad health system is in my posts.
Title: Re: DMSO+X Revisited 2019
Post by: hope794 on July 15, 2020, 11:28:04 AM
Absolutely OUTRAGEOUS! You did NOTHING, literally ZERO to get banned. This forum is getting delusional to me, even if i've always been in love with it. Why to watch melting? He's always been respectful and gave A LOT to this community.

Admins, please, can you kindly provide some further insight about this story?
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on July 15, 2020, 01:44:26 PM
He isn't banned.  Individuals may be put on watch after having been given several warnings to stop personally attacking others...name calling, etc.  it would have been helpful he had explain why he's on watch.  Also, posts aren't deleted...perhaps occasionally edited for content...removing copying complete posts one is responding to, name calling, etc. 
Title: Re: DMSO+X Revisited 2019
Post by: Whyisthishappening on July 15, 2020, 01:48:31 PM
can  MODS make public the REASON forum member MELTING is been WATCHED ?
Title: Re: DMSO+X Revisited 2019
Post by: RandyPE on July 15, 2020, 05:52:24 PM
One of the MANY things I tried for the first 2 years after I was diagnosed was DMSO and Iodine.

It's impossible to say what worked and what didn't, but 4 years after diagnosing my curve is imperceptible and only the hourglassing remains.

"Peyronie's disease occurs when the tissue along the shaft of the penis thickens, causing erections to become increasingly curved and even painful. Applying SSKI to the thickened tissue twice a day over several months can soften it considerably and eventually allow for more normal functioning." from https://www.icnr.com/articles/wondersofiodine.html

Also:

"Naturopathic Approach to Treatment
Because of the common delay in seeking treatment, patients with Peyronies Disease frequently present with a continuum of pathology which must be assessed in order to develop a treatment plan. Most of the cases I have seen are of the type I, and II variety. Other treatments for type III Peyronies Disease will need to address the underlying cause of the erectile dysfunction, even with successful resolution of the pathology caused by the Peyronie's disease.

The goal of treatment is to stop the underlying inflammatory process while also providing therapy that allows the damaged tissue to remodel. To accomplish this, I use the following protocol:

1 Vitamin E: 1000 IU/day
2 Vitamin C: 3000-5000 mg/day
3 CoQ10: 300 mg/day
4 L-Arginine: 1000 mg/day
5 A homeopathic combination remedy of Arnica 30C, Bellis perennis 30C, and Calendula 30C: 10 drops BID
6 Topical potassium iodide applied at bedtime to the lesion
7 Wet shorts treatment at bedtime to increase blood flow
8 Pulsed ultrasound 2 to 3 times per week, initially with potassium iodide and DMSO, for 10 minutes in order to break up the underlying plaques and fibrous tissue. Pulsed ultrasound must be used, as continuous ultrasound will cause a burn."

from: https://ndnr.com/mens-health/peyronies-disease-therapeutic-considerations/



It certainly didn't hurt, and again - who's to say if it helped or not. 

Randy
Title: Re: DMSO+X Revisited 2019
Post by: projectpd on July 16, 2020, 12:49:05 PM
you wore wet shorts at bedtime to increase blood flow?
Title: Re: DMSO+X Revisited 2019
Post by: RandyPE on July 16, 2020, 01:00:40 PM
Quote from: projectpd on July 16, 2020, 12:49:05 PM
you wore wet shorts at bedtime to increase blood flow?

LOL, I did not.  That was part of a longer quote from the page I cited.  (The quote starts with "Naturopathic Approach to Treatment" and goes through the end of my post.)

I did the iodine with DMSO and ultrasound, though.  Have also done the high dose Vit E, CoQ10 and the L-Arg, although I had done those before I saw that website.
Title: Re: DMSO+X Revisited 2019
Post by: DarrenBent on July 19, 2020, 10:44:01 AM
Just hopped on the DMSO bandwagon and started day 1 of treatment.

I've made two mixtures in two Amber glass dropper bottles:

1) DMSO + Vit C (and water and castor oil and lecithin)
2) DMSO + Potaba powder (and water and castor oil and lecithin)

The aim is to put Vit C one on in the morning for 15 mins followed by some VED and hand stretching, then same with the Potaba in the evening.

Investigating getting a Restorex too.

So far the mix (50% DMSO - 50% supplement and oil solution) seems fine and no burning or rash.
Mixture does look cloudy with a bit of a froth on top but I guess that's the oil and lecithin?

Sound about right to you, melting?
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on July 19, 2020, 11:49:52 AM
Awesome! Keep us posted.

I too am jumping on, but am waiting for the gel stuff from natures gift on amazon that is 70/30. will fuse the gel with iodine...try that and then do the mix youre doing. I have all the equipment.

doubt youll get melting on here anymore, he left his contact info but you can view his past comments on how he organized everything. youll probably be on your own from here as far as the experiment goes.
Title: Re: DMSO+X Revisited 2019
Post by: Paolo on July 25, 2020, 06:58:04 AM
Does any member have experience using Urea cream 10-25% for getting topicals into the penis?
Cheers
Paul.
Title: Re: DMSO+X Revisited 2019
Post by: Bent Ding Dong on July 25, 2020, 08:50:41 PM
@Paolo, yes I have used urea but I make the solution up myself. Using urea on it's own is great for better erections as it's 50% nitrogen and it's also very cheap. I have recently been experimenting with vitamin C taurine and sod with urea and am thinking about starting a thread about this as a DMSO alternative which doesn't make you smell like DMSO does or wrinkle up or discolor the penis.

In short, yes it does penetrate the skin.
Title: Re: DMSO+X Revisited 2019
Post by: DarrenBent on August 01, 2020, 11:40:20 AM
Has anyone else noticed their DMSO+X solutions smelling weird. My DMSO + Potaba mix smells fine, DMSO + Vit C mix is much cloudier and has a real gone off vegetables smell.
Title: Re: DMSO+X Revisited 2019
Post by: TonySa on August 01, 2020, 12:49:04 PM
Bent, you use urea on the penis and it helps w erections?  I understand this is a "digester" type solution good for callouses and such, what does it do to the skin?  What % is the urea?
Title: Re: DMSO+X Revisited 2019
Post by: hope794 on August 01, 2020, 03:04:26 PM
I've began to use urea AFTER DMSO and i've noticed way better erections. Does anyone know why?
Title: Re: DMSO+X Revisited 2019
Post by: Bent Ding Dong on August 02, 2020, 06:53:59 AM
@TonySa, with urea, there is a delayed reaction for better erections, if I apply it before bed I always wake up with better erections than I would if I didn't have it. It can have a drying effect on the skin but I just add a few drops of MCT oil to the solution and that stops the drying effect. Other than this, I notice no other negative effects from it. As for the %, I try to get half as much urea as water so 50%.

@hope794, I assume the better erections from urea comes from the high nitrogen in the urea, the one I use is 50% nitrogen.

Title: Re: DMSO+X Revisited 2019
Post by: hope794 on August 03, 2020, 04:47:27 PM
How does the nitrogen improve erections? i've found no articles / studies about it.
Title: Re: DMSO+X Revisited 2019
Post by: Bent Ding Dong on August 04, 2020, 09:08:13 AM
@hope794, you wont find articles on it as we are probably only a small few who have tried it. I can only go off my own anecdotal experiments.

Nitrates increase blood flow to the penis. Drugs like Viagra do this also. Viagra or Cialis do work better and quicker for erections than urea but a 4kg bag of urea from the hardware store will last you a lifetime and only cost $10.
Title: Re: DMSO+X Revisited 2019
Post by: projectpd on August 04, 2020, 12:55:47 PM
interesting.  not doubting it, but urea is the main component in urine, right? and some oils have transdermal properties. I am curious why this would not work/ or been common knowledge since ancient times.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on August 04, 2020, 07:06:18 PM
F*ck I wish there were more than one success stories tho, but well well.
Title: Re: DMSO+X Revisited 2019
Post by: Bent Ding Dong on August 05, 2020, 06:19:51 AM
@projectpd, yes urea is in urine but they make it from ammonia commercially. Well some people swear that drinking their own urine gives them great health but I'm not trying that!
Title: Re: DMSO+X Revisited 2019
Post by: hope794 on August 05, 2020, 01:06:01 PM
Godisreal, please consider that there are seriously a few people who tried this DMSO+X thing for more than a couple of times.

I already did my first 40-45 days of DMSO+X and i can say that i feel better.

My improvements are:

1. 90% disappeared pain
2. Feeling of softer penis
3. Feeling of less inflamed penis
4. Feeling of slightly better erections, about 10% improvement (i have ED, F~@< my life and this disease)
5. Feeling of a slightly increase in penile lenght, like 0.5 cm, but pay attention it's maybe because of the slightly better erections.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on August 07, 2020, 05:05:30 PM
I'm happy for you, man. Trying DMSO a couple of times and saying it don't work is stupidity, and that's some people on the forum. It's great that you're keeping at it.
Also, your improvements are exceptional, but they're not exactly what you want, as I understand.
Do you know what's causing your erectile disfunction?
I'm planning on hiring a professional pelvic floor specialist in the further future (I'm f*cking broke rn lol), I definitely believe that REAL pelvic floor therapy could do more for us Peyronie's sufferers than we think.
Title: Re: DMSO+X Revisited 2019
Post by: hope794 on August 09, 2020, 09:47:02 AM
Dearest godisreal, thank you for your kind words. After your PM, i've decided to reply here.

I'm trying various formulas. Everything of what i say, should be calculated on a 30mL bottle, except the 2°.

1. DMSO 90% + 10% purified water + Vit. C (until total diluition)
2. DMSO 70% (21mL) + 1 mL purified water + 9mL voltaren vials, which is an antinflammatory (diclofenac)
3. DMSO 70% (21mL) + 8ml Isoptin vials (which is the italian name for verapamil) + 1ml purified water
4. DMSO 90% (27mL) + 3mL purified water + ALCAR (until total diluition)

So basically what i do, for example in the formula n°1, is just taking 27mL of DMSO, then add the 3mL water to make the burn reaction happen inside the bottle, then after 5 minutes i add Vit . C until total diluition. Easy as that. I suggest, after washing the DMSO away (usually after 15 minutes) i put on some Urea cream, or your penis will look like a 90 yo penis xD

But please note that, IMHO, the work has been done mostly by the DMSO.


PLEASE NOTE ALSO
that yes, i had a slight improvement, but i'm not cured AT ALL, i still have some pain sometimes and i fear that, if i'll stop DMSO, things will get crap again. So it's not a miracle, for now.

I'll keep doing this since the 6 months, then i'll decide if continuing or not.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on August 09, 2020, 01:58:48 PM
Greatness! Your input is greatly appreciated! A few additional questions bro:
#1: Do you mix everything in a brown glass? Or what kind of "bottle"?
#2: Where did you get your hands on Verapamil? Here in Sweden, it's prescribed by a doctor, only.
However, I'm familiar with the dark web and will prolly be able to get it there otherwise.
#3: How do you purify your water? Or do you buy? Please, explain.
#4: Lastly, you're saying things will get crap again if you stop... what is your main issue with Peyronie's? Is it a curve? Or is it erectile disfunction? Or both, perhaps? I'm asking because it's possible DMSO can have a different effect on different problems.
Thanks again, man.
Title: Re: DMSO+X Revisited 2019
Post by: johnd1201 on August 09, 2020, 04:29:50 PM
Do you add anything to thicken up the mixture? If not, isn't it runny?
Quote from: hope794 on August 09, 2020, 09:47:02 AM
Dearest godisreal, thank you for your kind words. After your PM, i've decided to reply here.

I'm trying various formulas. Everything of what i say, should be calculated on a 30mL bottle, except the 2°.

1. DMSO 90% + 10% purified water + Vit. C (until total diluition)
2. DMSO 70% (21mL) + 1 mL purified water + 9mL voltaren vials, which is an antinflammatory (diclofenac)
3. DMSO 70% (21mL) + 8ml Isoptin vials (which is the italian name for verapamil) + 1ml purified water
4. DMSO 90% (27mL) + 3mL purified water + ALCAR (until total diluition)

So basically what i do, for example in the formula n°1, is just taking 27mL of DMSO, then add the 3mL water to make the burn reaction happen inside the bottle, then after 5 minutes i add Vit . C until total diluition. Easy as that. I suggest, after washing the DMSO away (usually after 15 minutes) i put on some Urea cream, or your penis will look like a 90 yo penis xD

But please note that, IMHO, the work has been done mostly by the DMSO.


PLEASE NOTE ALSO
that yes, i had a slight improvement, but i'm not cured AT ALL, i still have some pain sometimes and i fear that, if i'll stop DMSO, things will get crap again. So it's not a miracle, for now.

I'll keep doing this since the 6 months, then i'll decide if continuing or not.
Title: Re: DMSO+X Revisited 2019
Post by: projectpd on August 09, 2020, 04:43:21 PM
I think you are too focused on amounts /percentages and not on 'combinationality'.  Where you can combine the agents, then you can apply more frequently and thereby multiply effectiveness. what is the constraint? pH is one, but you can use pH strips.   I heard 3.5 is optimal for vit C. (example)
Title: Re: DMSO+X Revisited 2019
Post by: hope794 on August 10, 2020, 03:47:30 PM
I'll answer to anyone:

GODISREAL:

#1: Do you mix everything in a brown glass? Or what kind of "bottle"? I mix it in a brown glass bought on Amazon. Sorry, can't insert the link here, but you'll find easy.
#2: Where did you get your hands on Verapamil? Here in Sweden, it's prescribed by a doctor, only. I know the guy who works in the drug store near my house and i convinced him to give me the drugs without prescription, but he'll soon begin to be suspicious.. :(
However, I'm familiar with the dark web and will prolly be able to get it there otherwise. I DONT RECOMMEND THIS WAY.
#3: How do you purify your water? Or do you buy? Please, explain. Bought on Amazon already purified water.
#4: Lastly, you're saying things will get crap again if you stop... what is your main issue with Peyronie's? Actually, curve is not an issue for me. I've had a penis of about 18cm, then after Peyronie's it's getting straight to 15.5 cm and i fear it's gonna shorten even more. Little losses in girth too.. But the worst part is the Erectile Dysfunction, my erection is crap, can't mantain it. So basically, no more satisfying sex .. 

JOHND1201:
Do you add anything to thicken up the mixture? If not, isn't it runny?
Yeah, it's very runny, i just put some drops, then spread a little bit, then more drop and so on until i put about 3 pipes, which equals to about 3mL of DMSO+X.

PROJECTPD:

I think you are too focused on amounts /percentages and not on 'combinationality'.  Where you can combine the agents, then you can apply more frequently and thereby multiply effectiveness. what is the constraint? pH is one, but you can use pH strips.   I heard 3.5 is optimal for vit C. (example)


I know, unfortunately my chemical background is nearly zero and my experiments are really amateur.

Tomorrow i'll buy another drug, and i'll try to add oral anti-histaminic and a vial of anti-histaminic to the DMSO.
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on August 10, 2020, 10:03:16 PM
Guys,

Lets try to keep this post focused on DMSO and if youre using whatever substance with it than cool. But this chat has really become a sink hole of multiple convos which makes it harder for someone who wants to use DMSO and look for valuable info on here. Im sure there are other valuable convo topics but lets be organized.
Title: Re: DMSO+X Revisited 2019
Post by: Fix This on September 29, 2020, 03:35:12 PM
Just an update all regarding this.

I haven't been on here for months so sorry for the late update

I mentioned on here a few months ago that I had developed some wrinkles due to DMSO usage/ over usage

The wrinkles all faded as far as I can see. I bought a jar of a retinol wrinkle cream on Amazon and used that for a few weeks , then just kind of stopped and forgot about it

So all seems good. But if using DMSO and another mixture I would advise to premix in advance as it generates a  great deal of heat immediately upon mixing ( with X ). And to wash off after 5 or 10 , 15 minutes or similar

But if you do end up getting wrinkles from it, stop using and try some Retinol Cream!

I'm now using a little bit with pre mixed ( a few times a week ) whilst using a traction device
Title: Re: DMSO+X Revisited 2019
Post by: Tom_E on October 02, 2020, 12:43:02 AM
MY EXPERIENCE WITH DMSO PLUS OTHER THINGS

I tried DMSO plus water, let it cool down, then plus vitamin C and over time it did make the plaque softer and I think this helped to stretch it a bit more, via my Restorex.
I did get some wrinkles and redness sometimes, but then I reduced the amounts and was better.

I have a little bit of calcification so tried: DMSO with water and Liquid Potassium Iodide KI SOLUTION.  I heard it can help sometimes with scars in general.  Maybe would work for plaques.
It did make the plaque softer.  Too early to tell if it reduced any calcification. 

BUT, within a day of using the DMSO\water\Liquid Potassium Iodide mix, any wrinkles and redness left over from the previous Vitamin C mix, completely disappeared and skin was healthy and pink. 

Please note this could be for various reasons. I sometimes would use too much of the DMSO\water\Vitamin C perhaps.
Also please note, it has been said by some to not use Potassium Iodide too long, as it can affect some people's thyroids\other things in some ways.  If you do use it a lot, get your thyroid tested sometimes.

One negative experience with DMSO, is when I would sometimes fill half a glass with a 4 ounce mix and dip my penis directly in it and keep it submerged for 15 min.  Pickled Penis way.  Dont do this. lol  Or at least be aware bad stuff can sometimes happen.  Did this a few times and it made me feel sick sometimes and I did not poop for 4 days straight.  It just soaks into too many other areas of the body if done this way. 

Overall, using small amounts and stretching via a Restorex and Erection Pump device, did reduce my curve a bit and I gained a bit of length.  This is over 6 months.

I am doing Xiaflex shots now, so not doing the DMSO or Erection Pump things, but still can do restorex and manual stretching.

QUESTION: Does anyone know the best ways to reduce calcification in plaque?
So far I have heard to take Pentox and try to get Liquid Potassium Iodide KI solution into the skin with dmso and Liquid Potassium Iodide KI can soak in a bit by itself to.
Any other ideas for Calcification?

Hope some of what I said helped some here.
Cheers my brothers!
Tom
Title: Re: DMSO+X Revisited 2019
Post by: Fix This on October 24, 2020, 04:13:01 AM
Hi all

Has anyone ever tried DMSO with Cialis ? It seems that Cialis ( Tadalafal ) has a molecular mass of 389.4 g/mol which I believe is well within the limits for succesful transdermal absorption using DMSO yes ?

The general consensus on Cialis sees to be  that it is anti fibrotic and is often touted as being one of the more ' successful' oral treatments for peyronies.  So it stands to reason that if it can be transdermally applied using DMSO then it will have more direct benefit?

So anyway, I crushed and mixed 2 * 25 mg Cialis tabs with water and DMSO in brown bottles this morning. Approx 60% water 40% dmso ratio. Will see how it goes and let you know

If anyone else has tried this , how did you get along ?



Title: Re: DMSO+X Revisited 2019
Post by: Holistic on October 25, 2020, 07:54:30 PM
Quote from: Fix This on October 24, 2020, 04:13:01 AM
Hi all

Has anyone ever tried DMSO with Cialis ? It seems that Cialis ( Tadalafal ) has a molecular mass of 389.4 g/mol which I believe is well within the limits for succesful transdermal absorption using DMSO yes ?

If you look in this convo, there is discussion of the molecular weight any added component must be for DMSO to carry it into the skin. Im not sure what the cut off point is for the numerical weight though.

Title: Re: DMSO+X Revisited 2019
Post by: NeoV on October 26, 2020, 10:09:59 PM
Quote from: Tom_E on October 02, 2020, 12:43:02 AM
Pickled Penis way. 

Tom, this gave me the best laugh I've had on this forum for a while, LOL!! Thanks for that. Sounds like it really messed you up!

Hope everyone keeps us updated and is careful. If it weren't for the messiness, steps and time required, I suppose many more men would be trying DMSO.
Title: Re: DMSO+X Revisited 2019
Post by: AnonDoc on October 28, 2020, 06:58:40 AM
Quote from: aquintance22 on January 13, 2020, 03:35:45 PM
Anyone has tried DMSO + Serrapeptase or other enzymes or would it be not absorbable or only working in the intestines?

I've used a nattokinase/serrapeptase combination topically, More frequently on the arms, with systemic spread. Be careful of dosing and keep to small amounts.

Notice softening/stretching of penis and lightening of long time stretch marks even with very infrequent use. It Gives me insomnia
Title: Re: DMSO+X Revisited 2019
Post by: AnonDoc on October 28, 2020, 07:24:52 AM
Anyone try a topical/transdermal collagenase or xiaflex?

I've seen a report online of someone doing this for dupuyten and said the cured it.
Title: Re: DMSO+X Revisited 2019
Post by: Fix This on October 29, 2020, 02:53:05 PM
Quote from: Holistic on October 25, 2020, 07:54:30 PM


Thanks Holistic. Yes I know thanks. It would seem to be around 1000 g/mol accirding to earlier in this thread.

I was more trying to find out whether anyone had tried DMSO with Cialis really

Many thanks

Fix
Title: Re: DMSO+X Revisited 2019
Post by: Mr man on November 22, 2020, 05:10:10 PM
This has been the most informative thread on DMSO. Am fighting to reduce symptoms. Before relenting to surgery.

For the record. Just started using my DMSO formula today. 3 parts DMSO, 1 part castor oil, and 0.5 parts vitamin E oil.

After the first day. Penis is really soft and pliable. Can clearly feel the plaques now. There are 4 or 5.

Have ordered vitamin c powder and sodium thiosulfate. Probably use these neat. Alternative with my aforementioned formula.

Just one question please. What is ACV? It's mentioned frequently at the beginning of this thread. Thanks.
Title: Re: DMSO+X Revisited 2019
Post by: Tom_E on November 24, 2020, 11:37:18 PM
ACV=Apple Cider Vinegar
Title: Re: DMSO+X Revisited 2019
Post by: Tom_E on November 25, 2020, 01:18:45 AM
Honestly guys, I did notice some positive changes in curve and length using the DMSO+Vitamin C and DMSO+ sski potassium iodide.  I used one mix for a week and took a week off as it made me really constipated,  then repeated with this mix and pattern for a a month.  Took 2 weeks off and tried the other mix mentioned above and did the same pattern.  Please note, I would use a glass eye dropper to drip it onto my penis, over the plaque area, and drips would fall into a bowl.  sucked up the drops into the dropper and did it again, over and over for 10 to 15 mins while watching tv.  Get a glass eye dropper and avoid getting the solution in the rubber squeezing part.

I was sitting on my yoga mat with warm ceramic bowl, balls on one side and dick inside bowl, I held my penis up though, so drips would not go on the head of the penis.  I would just keep dripping on top of dorsal plaque area and it would hit that area and then drip around penis and into bowl.  some would stay on for a bit.  I would take small breaks during that 15 min dripping sessions to rest and watch tv.  pretty much dripped the solution on 35 times during the 15 mins.

Avoid getting drippings on head or balls, it can sting, or at least it stung my balls and some say avoid the head if possible,  unless your plaque is under head, then ask around if getting dmso+mix is ok for head.  sensitive skin area thats probably used in the part of the arousal process.  Plus not sure if getting these chemicals into your ball sack is a good idea...could mess things up maybe.

Personally, I dont use too much of these mixes.  One 15 minutes session would use this mix
MIX 1:
mix 10 drops of 100% dmso with 10 drops of distilled water in a glass
wait 2 minutes so it can cool
add teaspoon of vitamin C powder or make a judgement call to keep it sticky and not too dry
leave that in the glass cup

warm a bowl up, sit down on yoga mat, balls on one side, dick on the other and drip away, suck up drippings and drip away again, for 15 minutes, take breaks, watch tv.  I suggest star trek discovery or Mandalorian or the Outpost tv series.  Actually not that last one as you might get a boner. LOL  shes hot.
When done, clean up.  Later in the evening I use traction device.(Restorex)
I use this mix off and on over a month, 1 week on and 1 week off.

I do the same with MIX2:
MIX2 = mix 10 drops of 100% dmso with 10 drops of distilled water in a glass
wait 2 minutes so it can cool
add 10 drops of sski potassium iodide
leave that in the glass cup

warm a bowl up, sit down on yoga mat, balls on one side, dick on the other and drip away, suck up drippings and drip away again, for 15 minutes, take breaks, watch tv. avoid boners.
When done, clean up.  Later in the evening I use traction device.(Restorex)

not sure how to make this mix stick to avoid dripping it on over and over, but I got used to it and took breaks.
I take a full week or 2 off here and there, as dmso or something in the mix, really makes me constipated.

These dripping sessions last 7 to 10 days and then I take a break from them, to get dmso+mix out of my system.  I feel it is getting into my bowels and other areas down there.
I notice on day 3 of dripping the dmso+mix, the plaque definitely gets much softer.  everything gets softer it seems, but more importantly, I believe this softness helps to stretch the plaque and penis itself, to gain length.  Over time, I actually could feel the plaque get thinner and longer in the direction I was stretching it.  hopefully the dmso+mixes are actually eroding the plaque but at least I knew it was helping me to stretch it for sure.  Please note, after you stop using dmso+mix for several days, the plaque will go back to original hardness and some of the shape went back to normal but not all.  some of the shape was still stretched in the direction I was pulling it with traction. 

Did the dmso+mix thing plus traction thing off and on over 6 months and it did help significantly.

Before that, just traction alone did a little, but not much.

Before that, tried a series of 5 Verapamil injections plus traction, did not do that much for me personally, so stopped at 5 and not the usual 6

Most recently, a series of 4 XIAFLEX shots helped a lot.  Note:  I used traction after each shot for a month.  I got 1 shot every 5 to 6 weeks.
I noticed nothing much until the 3 shot and then wow, 12% reduction in curve after stretching it for a couple days.  4th shot, another 8% after stretching for a few days.  4th shot hurt a bit too much so took a break for awhile, but very happy with them and I may stop there.  4th one really hurt hehe, and I get worried about any kind of rupture, although it never happened with me, thankfully.
NOTE:  would not do the dmso+mixes near the times I did xiaflex treatments.  I would stop the dmso at least 4 days before I would get a shot, as I felt it would be hard for the doc to feel where to inject me as the plaque was too soft sometimes. I would not do any dmso+mixes again for 4 weeks after the shot.  I used traction during those 4 weeks though.  after 4 weeks, I would gently make love to my partner or masterbate gently here and there over a few days, as you cant do that for 4 weeks after a xiaflex shot.  After the 4 weeks, I would use dmso for a week, plus traction, then stop for 4 days and then get another shot.  Really guys, dont mess around with xiaflex.  it eats away at your plaque hopefully but there are no known studies of having xiaflex while your dick is soft with dmso...the xiaflex may eat too much or too little or eat something it shouldnt and then boom, rupture time... really bad news my friends.  Never happened to me but holy crap just avoid that kind of situation if you can.

So my journey has been exactly one year now, and thanks to all the advice I got from you guys and this site...etc, I went from 60% dorsal curve with a loss of 1.5 inches, to a 38% dorsal curve and gained 2\3 of an inch back.  I will continue to the Restorex traction.  by the way, I lightly warm my penis first before traction.  not too hot though, google it.  Too hot is very bad.  just keep it lightly warm before you start to stretch it. I also will do some vacuum therapy(Soma Therapy ED) sometimes.

Hey thanks guys!  You all helped me very much!  I will keep at it and later when reaching my goal of 30% curve, which is fine with me, I will do the above things just part time as i am functioning ok now, will do a maintenance dose of stretching mostly here and there and always be careful making love, avoid certain positions.  Be gentle and firm but not crazy dive bombing maniacs lol.  Also take it easy choking the chicken my friends.  Adjust your technique to a safer one.

You all are awesome.  Keep helping each other.  Keep up the good work!  This website is awesome!
Tom
Title: Re: DMSO+X Revisited 2019
Post by: NeoV on November 25, 2020, 08:53:10 PM
Love your post Tom!!!!  ;D

It's so great to see you try multiple things at once including Xiaflex, traction, VED, and DMSO, and to see good results!
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on December 16, 2020, 09:59:26 AM
Just started my official journey with DMSO + X. WITH CONSISTENCY.
Did the first session today. I will aim at doing 1-2 sessions per day. Sessions meaning dripping & massaging a solution on my dick; solution consisting of DMSO, Vitamin C Acid, Castor Oil and a smidge of Xhantan to thicken the solution a bit.
I will do this for as long as it takes lol.
Does anyone know how to properly store the solution? With DMSO and everything? Is the fridge ok?
Also, is it better to have less thick solution or more thick? Perhaps it does not matter?
Also, without discipline, you will never get cured from this. Remember that.
If anyone has any suggestions on what solutions I should try, let me know!
The current solution I'm using was originally made the great melting.
It's very sad to see that he hasn't been online for so long because he got banned for some nonsense.
Horrible decision by the admins. He is, without a doubt, one of the most important people in the history of this forum.
Title: Re: DMSO+X Revisited 2019
Post by: LuisFernandez on December 16, 2020, 12:45:08 PM
Godisreal,

I'm also finally about to start DMSO. Stayed away from it because i thought it was too complicated, but after a few weeks studying it - it really isn't.
So I would recommend adding PABA/POTABA and perhaps some iodine mixes.

I'm going to start with DMSO + PABA + ACV + VIT-C + IODINE
Also going to try mixing in Pentox

Not sure if i'll mix PABA + VIT-C + Pentox + IODINE in the same batch. Probably not, just create different batches. I'll also update my progress and batches here as i go.
Title: Re: DMSO+X Revisited 2019
Post by: Tortão Pra Direita on December 16, 2020, 04:51:31 PM
Quote from: Godisreal on December 16, 2020, 09:59:26 AM
If anyone has any suggestions on what solutions I should try, let me know!

Check about "Curowhite". It's a white curcumin that doesn't stains and it's much more absorbable.
I think it would be a nice add on.
I really don't like DMSO, but I'm planning on stacking Curowhite + Pentravan.

If you want more reading, check this link. This guy explains how Curowhite was made.
https://www.reddit.com/r/NootropicsDepot/comments/j6e73p/curowhite_and_the_color_of_curcumin/
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on December 16, 2020, 05:24:13 PM
LuisFernandez
Aight man. So basically, you crush your pills (Pentox, IODINE, PABA) and put it in what? A mixer?
Or how do you turn it to liquid form? Pretty interesting.
Do you mix everything with a electric mixer? I, personally mixed manually.
But as long as you don't mix the DMSO in the plastic mixer, that's a good move to mix the other agents in the mixer.
One thing I noticed after just one application is coolness in my penis (lowered inflammation).
This is gonna be interesting. Wishing you best of luck, man. Please keep me informed.
Tortão
With DMSO being the most powerful natural drug-delivering agent, I can't say that leaving DMSO out of the formula is a good idea if you want to see good results.
As it has been said many times here: it's very difficult for any substances to penetrate further than the skin without a delivery-man like DMSO :)
Title: Re: DMSO+X Revisited 2019
Post by: lanyc on December 18, 2020, 11:24:23 AM
I just have a quick question...I've read thru these threads...I get the mix but as far as applying...what is the preferred method.?  Once its mixed how is it applied and for how long..?  If someone could give me an idea on how to use the mix that would be great...thx thx..
Title: Re: DMSO+X Revisited 2019
Post by: LuisFernandez on December 18, 2020, 05:28:00 PM
Quote from: Godisreal on December 16, 2020, 05:24:13 PM
LuisFernandez
Aight man. So basically, you crush your pills (Pentox, IODINE, PABA) and put it in what? A mixer?
Or how do you turn it to liquid form? Pretty interesting.
Do you mix everything with a electric mixer? I, personally mixed manually.
But as long as you don't mix the DMSO in the plastic mixer, that's a good move to mix the other agents in the mixer.
One thing I noticed after just one application is coolness in my penis (lowered inflammation).
This is gonna be interesting. Wishing you best of luck, man. Please keep me informed.
Tortão
With DMSO being the most powerful natural drug-delivering agent, I can't say that leaving DMSO out of the formula is a good idea if you want to see good results.
As it has been said many times here: it's very difficult for any substances to penetrate further than the skin without a delivery-man like DMSO :)

Godisreal,

I still haven't started treatment, still waiting for the DMSO and PABA to arrive. Kind of mad i waited this long, but hopefully it provides some results.
PABA comes in powder, for Pentox i bought a pill crusher. I plan to just mix it with the DMSO in a glass jar. Then i can apply with a glass eye dropper.

I will also try to emulsify into a gel-like substance as melting described in this thread. I'll post pics and stuff once i get going.

Good luck.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on December 19, 2020, 08:17:56 PM
Sounds good, Luis. But what benefit would PABA give you?
POTABA/PABA is a classic treatment and is a form of Vitamin B if I'm not mistaking?
I'll look into it. As for crushing Pentox. Yes, I like the idea so I will definitely do it as well.
Do you use anything to emulsify the solution? I use castor oil mixed with everything else (DMSO, Vit C etc). Is that ok? Or should I apply castor oil afterwards, perhaps?
Anyway, let's beat this disease. Good luck, man. Keep up the good work and stay positive.
Title: Re: DMSO+X Revisited 2019
Post by: LuisFernandez on December 19, 2020, 09:35:15 PM
Godisreal,

Check out Melting's reply #15 to this thread. Apparently PABA is basically POTABA, but honestly i'm not sure what the difference is. I don't have a prescription for Potaba so using paba is the best i can do right now.

I'm unsure what the mechanism of action is for some of these ingredients, but PABA seems like a good start.

As for castor oil. I believe you use it both for the mix and after application.

In penis enlargement circles it is said that using DMSO + PABA softens up the tunica and makes it more soft and pliable. I'm combining DMSO+X treatment with traction and VED.

I made my first batch of DMSO+X yesterday. I basically bought all the ingredients:

DMSO + ACV + CASTOR + PABA + PENTOX

Ingredients:
- DMSO 99.9%
- PABA powder
- Pentox
- Apple Cider Vinegar (ACV)
- Vitamin C Powder
- Castor Oil
- Lecithin
- Xanthan Powder

Tools:
- Mason Jars
- Glass Eye Dropper
- Pill Crusher
- Handheld Mixer w/ Metal Tip (https://www.amazon.com/gp/product/B01E45VBFO)

Steps:
- Draw 50ml of DMSO and place into jar #1
- Draw 2.5ml of ACV and place into jar #1
- Mix jar #1 and let cool
- Draw 12.5ml of ACV into jar #2
- Add PABA powder until it stops dissolving into jar #2 - mix
- Crush 3 pills of Pentox and add into jar #2 - mix
- Draw 5-10ml of Castor Oil into jar #2
- Pinch of Xanathan and some Lecithin - mix
- Pour the contents of jar #1 into jar #2 or place them into a separate jar
- Mix thoroughly - add PABA, Xanthan, & Lecithin until it starts to create a gel-like substance - more PABA the better
- Let sit overnight

Application:
- Apply small amount into your hand and leave for a couple of hours to make sure there's no adverse reaction
- Apply all over penis in tub or somewhere easy to clean
- The gel mix will stick to your penis easily
- Let sit 15min, reapply if desired for another 15min
- Wash area thoroughly - i took a quick shower
- Dry thoroughly and apply castor oil
- Wear white underwear or pajamas

Notes:
- This is the DMSO i bought: https://www.amazon.com/gp/product/B01BSYQ0XC/
- I didn't get any weird taste, which tells me i may not have used enough DMSO
- I did feel some slight tingling inside my penis, i took this as a good sign
- After I washed i did a session with my VED to try and maximize effects
- Planning on applying 2x/day
- Some pictures (NSFW): https://imgur.com/a/RhNIvRf
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on December 20, 2020, 01:45:30 PM
Great answer. Luis. But why white underwear and not black? Is there a problem with leaving the DMSO on and having darker underwear on? Because that's what I'm doing lol
Title: Re: DMSO+X Revisited 2019
Post by: LuisFernandez on December 20, 2020, 05:18:09 PM
Quote from: Godisreal on December 20, 2020, 01:45:30 PM
Great answer. Luis. But why white underwear and not black? Is there a problem with leaving the DMSO on and having darker underwear on? Because that's what I'm doing lol

I believe melting mentioned to use white underwear in one of the earlier posts. This is because there are no "toxic" color dye which can be absorbed by the DMSO into your system. It's just a bit safer. But honestly, i think that as long as you clean really well then there shouldn't be any problems.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on December 21, 2020, 07:35:58 AM
Interesting, Luis.
I'm gonna have to discontinue my DMSO use until I've acquired a few more items, honestly.
While inflammation has been lowered, MORE PAIN in waves has come which is obviously fkn weird.
But i bet it's because there's probably toxic color dye in my systems or something.
Let's hope I'm not sterile lol.
Also, what about dmso on our balls? Is that dangerous?
Lastly, I'm not scared away easily from treatments like this but there's a line that can be crossed, and I just crossed it.
I'm gonna have to rethink my situation before going on with DMSO + X.
The reason I let my DMSO + X sit for 5-15 min and then I just put my dick back in the underwear and keep on with my day is because I read that DMSO is quickly absorbed into the skin?
And that's why I thought it'd be no problem. But I might be wrong...
Title: Re: DMSO+X Revisited 2019
Post by: Anton36 on December 21, 2020, 02:02:32 PM
I prepared own DMSO.

   I used DMSO, Castor Oil, Vitamin C.

   My question is, how many times should I use this mix. And after using DMSO should I wash my penis ? Thanks in advance
Title: Re: DMSO+X Revisited 2019
Post by: LuisFernandez on December 21, 2020, 07:22:01 PM
Quote from: Godisreal on December 21, 2020, 07:35:58 AM
Interesting, Luis.
I'm gonna have to discontinue my DMSO use until I've acquired a few more items, honestly.
While inflammation has been lowered, MORE PAIN in waves has come which is obviously fkn weird.
But i bet it's because there's probably toxic color dye in my systems or something.
Let's hope I'm not sterile lol.
Also, what about dmso on our balls? Is that dangerous?
Lastly, I'm not scared away easily from treatments like this but there's a line that can be crossed, and I just crossed it.
I'm gonna have to rethink my situation before going on with DMSO + X.
The reason I let my DMSO + X sit for 5-15 min and then I just put my dick back in the underwear and keep on with my day is because I read that DMSO is quickly absorbed into the skin?
And that's why I thought it'd be no problem. But I might be wrong...

I wouldn't overthink that a dye is somehow creating pain. It's just to be extra safe. Certainly try to avoid the balls, but IMO it shouldn't be TOO dangerous. DMSO, PABA, etc are relatively benign substances - but best be safe and avoid it. I tend to place a paper tower between by shaft and my testicles to try to avoid rubbing them.

Title: Re: DMSO+X Revisited 2019
Post by: Tortão Pra Direita on December 22, 2020, 05:05:48 PM
Maybe this is a stupid question, but wouldn't be better to inject the solution under the penis skin? I mean, no need to stick the needle in your tunica, just lift the penis skin and inject the solution using an insulin needle. This way you guys would avoid an entire skin layer.
Title: Re: DMSO+X Revisited 2019
Post by: Mr man on December 22, 2020, 06:18:17 PM
Quote from: Tortão Pra Direita on December 22, 2020, 05:05:48 PM
Maybe this is a stupid question, but wouldn't be better to inject the solution under the penis skin?

This is a bad idea. Injecting subcontaneously invariably leaves tissue with a reservoir of DMSO solution sitting inside. it's like hitting it with a bomb. Rather then a gentle spray from above.

Having some medical training in this area. I decided to try this. On a tiny scale. No more then .5ml for research purposes.

Please dont do this. It was done on another study that is on-going. Injecting mixture with 50% DMSO + 50% X is way to strong for soft tissue. Never mind 70/30. Lumps can form.within. Skin will be stressed. The safe ratio is 3-5% DMSO + 97% saline solution. Never inject oils of any sort. There is a good chance of poisoning. That includes castor oil. At that ratio. There is no potential benefit at all.

No question is a stupid question, but please stick to safe practice. Injecting requires education, a lot of knowledge, and research in safe preferably laboratory type environment.  Where reaction to chemicals can be recorded or treated should it be adverse.

Leave the tissue testing for lab rats
Title: Re: DMSO+X Revisited 2019
Post by: Tortão Pra Direita on December 22, 2020, 09:04:08 PM
Thanks for your answer!
DMSO is really strong, I tried to use it for a few days but give up for this reason.

There are substances that are more gentle, like Pentravam. Here, in Brazil, doctors prescribe pentravam + verapamil.
I'm planning on stacking pentravam + curowhite. I think this is an interesting combo.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on December 30, 2020, 08:58:12 PM
Does DMSO react with cotton? 100% cotton-underwear? (white)
Title: Re: DMSO+X Revisited 2019
Post by: LuisFernandez on January 23, 2021, 09:19:44 PM
@Godisreal,

I think 100% cotton underwear would be safe. I recently changed storing my DMSO mixes on glass bottles with corkwood tops. I was seeing some rust on metal lid containers.

Things have been going well, I am actually seeing some relatively good improvements. Better stretch on flaccid and slightly more pliable scar tissue. Will continue my applications.

Right now I have two mixes that i apply twice per day 45-60 each session.
1. DMSO + ACV + Castore Oil + Pentox + PABA
2. DMSO + ACV + Castor Oil + Vitamin C + Magnesium

I use Lecithin and Xanthan as emulsifiers. Mix #2 actually turns into a gel-like substance that's easy to apply. Mix #1 remains somewhat runny. So I apply mix #1 for 30 min then mix #2 for 30 minutes each session.

I'm also diligently doing traction and VED daily. Seeing good improvements with all of this so far.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on January 28, 2021, 07:21:20 AM
Great work man. I'm glad it's helping you.
But I have to ask once again:
What exactly do you use to not get any DMSO + X on your balls? Do you place some kind of cloth or what do you do? I'm tryna make sense on exactly WHY I have this problem?
Because you can't use any material to cover your balls if the cloth reacts with the DMSO, right?
I've had scrotum-discomfort since yesterday because I accidentally got some DMSO on my balls while treating my penis. Really fkn annoying, to be honest.
Especially when all ingredients are natural in my mix (VIT C, DMSO, XHANTAN & CASTOR OIL).
One could argue that there shouldn't be discomfort with these type of natural and, quite frankly, beneficial-for-testicular-health ingredients, right?
In by that I mean Vitamin C, which has been proven to be beneficial for testicular health.
Rest of the ingredients are also  just natural, nonetheless
Would a thick white cloth be okay to place on my balls? To avoid DMSO coming onto my balls?
Or would this react with dmso? I can't find sh*t about this online even after reading 5 full articles about "DMSO, Risks & Uses" etc etc.
What should I do? Please give me some insight, lads, so I can stop having this ridiculous problem.
Thanks
Title: Re: DMSO+X Revisited 2019
Post by: Asphyxia on January 28, 2021, 10:42:15 AM
If you are planning to try a traction device soon then maybe if you put dmso and then do traction then your penis wont wiggle on your balls as much, i honestly havent paid attention because it doesnt bother me and i know that traction can be pointed upwards which i rarely do, so that might help.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on January 28, 2021, 04:06:21 PM
Asphyxia
Yeah, man, that might be right. I just read an article regarding DMSO being used for treating discomfort caused by testicular cancer, so I'm not as worried anymore.
However, do you wash your dick before you apply the mixtures?
I never do. I just do it afterwards. But should I wash it clean before applying?
Also, do you know if I can put a white cloth between my dick and my balls? Is that safe?
My apologies if I sound like some worried teen lol, I just wanna be safe using this.
I did use melting's measurements when making the mix so it should be all right.
But how much do you guys apply every time? Please, I want everybody's opinion.
Do you guys just use a drip on the plaque area? Because I pour out a good deal on the whole dick.
Maybe that's not a good idea?
Title: Re: DMSO+X Revisited 2019
Post by: LuisFernandez on January 28, 2021, 08:46:04 PM
Godisreal,

Check out the first picture here: https://imgur.com/a/yXtZuOq
I simply use some paper towels between my penis and my scrotum. This keeps the DMSO out of my balls, though it's not perfect. I'm not particularly worried about my testicles and DMSO - mainly because i don't plan on having more kids.

I think a white cloth is safe as well, in fact i may try that and save on paper towels.
I apply a LOT of the stuff, though i don't like to waste it. I'll even reapply after a few minutes after the mix has dried up a bit. The idea is to keep the scar tissue soaked in the mix as long as possible.

Best.
Title: Re: DMSO+X Revisited 2019
Post by: LuisFernandez on January 30, 2021, 12:58:35 AM
Hmm, apparently mixing magnesium with Vitamin-C creates: "magnesium ascorbate".
I will stop mixing these two and create two separate mixes for magnesium and vitamin-c.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on January 31, 2021, 02:09:58 PM
I understand. Thanks for the answer Luis.
But I wanna have kids and I still have scrotum-discomfort and I'm fkn worried.
I'm surprised no other member has had this problem.
Also, there's not anything a doc can do, is it?
I thought I did enough research to put my mind at ease but no.
It's getting to my head. It's incredibly frustrating and difficult to battle Peyronie's just to get a rash and scrotum discomfort in return... and for what? For having DMSO on my ballsack for barely 5 minutes? Then I washed it away.
F*ck. I have stuff I need to get done. I don't have time to worry about DMSO problems.
This is absolutely ridiculous.
Should I be worried for infertility? I have, like I said, a rash and discomfort in the scrotum area.
I'm usually the most optimistic person on the forum lol but infertility and Peyronie's? 
Nope. That's too much for me.
Any suggestions?
Out of all the research I did, I found that DMSO is effective in storing frozen sperm or whatever.
And I also stumbled across some freak that splashed his balls in DMSO to be able to have kids with his wife, which obviously makes no freaking sense whatsoever.
Title: Re: DMSO+X Revisited 2019
Post by: Asphyxia on January 31, 2021, 02:59:51 PM
i would see a doctor, skin problems made me weary in the past from trying to solve them.
i thought il solve them on my own but it was spreading and i was given some cream and pills, i dealt with eczema, ringworm, impetigo
i think most of us wouldnt know which cream is safe for the balls and which isnt, im guessing it should be without steroids, either way the treatment depends on the diagnosis.

thats just my opinion though, im not too sure of it myself.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on January 31, 2021, 03:51:48 PM
I'm not worried about the skin, bro, I'm worried about sperm quality and the effect DMSO might have on sperm production and health.
It's a hassle.
The skin reaction is obviously from DMSO. My recipe came from melting suggesting 100 ml DMSO with diluting with water of a small amount.
And DMSO is considered dangerous to cells in amounts more than 0,5% purity.
And most guys here have at least 50% (after diluting), and I probably had 60-65% after I diluted with water.
I don't understand how we put this sh*t on our dicks? And there's not one warning from the ones that started these threads to avoid scrotum contact at all costs, which should be a clear indication. Lol I definitely should've made more research.
It's my own fault for trusting random forum members, blindly. 
Title: Re: DMSO+X Revisited 2019
Post by: Asphyxia on January 31, 2021, 04:26:37 PM
Well, maybe you should worry about the skin if you are worried about sperm quality, but again, i dont really know, in my opinion either way, better safe than sorry.

I found this
https://pubmed.ncbi.nlm.nih.gov/32825298/
Title: Re: DMSO+X Revisited 2019
Post by: LuisFernandez on January 31, 2021, 08:17:02 PM
Yeah recently i made a new mix and didn't test it beforehand and ended up getting a rash/dry skin. I believe i just mixed too much DMSO and just need to add more castor oil and of course test it on the arm beforehand.

I wouldn't really worry too much though, i'm just taking a break and applying castor oil, aloe vera, and skin moisturizer and keeping things clean. Just gotta be careful with the mixes and make sure to test.

If you look back, even melting burned his skin at the beginning.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on January 31, 2021, 09:52:28 PM
Yeah I don't know what's going on. There's a dull ache in the left part of the scrotum... and it's based off nothing, really. I hate being afraid all the time. I can't focus on what I want because of all these goddamn issues. Jan, I'm trying to soften the plaque of my penis causing the curve.
The skin rash and discomfort I had is gone but what's left is a dull ache, like I said.
Yeah, Luis but didn't you get the rash on the penis? Mine was on my precious ballsack.
There's only one more important body part than the penis, and that's the ballsack and the jewels.
It also seems like I completely forgot to clean the water through filters before mixing with everything too; because y'all did that, didn't you? Well, i didn't.
So I might have some metals and toxins in my ballsack as well. I'm actually laughing right now.
This whole thing is a massive joke.
Don't know if I should laugh or cry.
Anyway, if I'm infertile then jokes on me i guess. The whole life is just a massive joke anyway, and the Earth will keep rotating even if Godisreal can't have kids ahahaha
Appreciate the help tho fellas
Title: Re: DMSO+X Revisited 2019
Post by: Tom_E on January 31, 2021, 11:33:54 PM
You mentioned, "And DMSO is considered dangerous to cells in amounts more than 0,5% purity." - please provide your source of proof for this.  That is quite a claim.

Also, just try to relax my friend.  I know this all sucks, but trust me, getting too excited and upset can lead to mistakes and oversights and lack of focus. 
Try to approach this in a more methodical, careful, calm, step by step approach.  I know its not easy, but doing it more this calm way can lead to more success.  Stress can cause problems with your health so just keep that in mind and try to relax and do this step by step and see now things go. 
Youre in a good place.  this forum. 

As for your balls, separate them from the liquid in various ways.  be creative.  I believe glass or porcelain cups or bowls dont react to DMSO.  Use those for your balls in some way to keep them away from the dmso mix. 

Good luck man.  I have been all through this and I feel ya brother.  Try various other things that worked for others to, other than dmso.  Also get  healthy, so your body can be stronger to fix itself and also have a healthy chemistry inside your body and penis to avoid making plaque material. 

Good luck.
Title: Re: DMSO+X Revisited 2019
Post by: Asphyxia on February 01, 2021, 02:54:36 PM
Godisreal
I started to notice burning on the beginning of my scrotum so it seems you arent the only one, however i wiped it off and the pain was gone, i dilute the dmso with voltaren, i wondered why you use water instead voltaren?
Anyway voltaren alone never gave me scrotum pain, maybe if you will stop with dmso then consider that

Id probably put aloe vera on my scrotum if this was happening to me
Title: Re: DMSO+X Revisited 2019
Post by: Tom_E on February 01, 2021, 09:48:09 PM
voltaren was taken off the market in some areas for some reasons.  Something to do with the heart.  Perhaps google it just be sure guys.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on February 03, 2021, 11:12:42 PM
In Canada? Or what? It's very much on the market in many countries (whole EU)
Is Diklofenac bad? Seems like it would be good.
Asphyxia, why do you not use water?
Does DMSO get the heat reaction with Voltaren, u mean?
That's good then. How much Voltaren do you use  in your mix?
Title: Re: DMSO+X Revisited 2019
Post by: Asphyxia on February 04, 2021, 03:55:38 AM
I dont use water because i see it as a wasted potential of mixing dmso with something anti inflmmatory,
I put some black seed oil too and im eyeballing everything, but id say the dmso is around 40% and voltaren 30%
I use the 4% concentration voltaren

Im starting to think the scrotum burning/pain is from traction because i can get it after few hours too.

When i first used voltaren alone it was a cooling sensation,
Which i feel less after mixing
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on February 09, 2021, 08:48:57 PM
I think something is really wrong with my scrotum and my testicles.
Still have discomfort and weird bubbling sensations in my scrotum weeks after accidentally putting DMSO on my balls.
Then I remembered months back when I thought it would be okay to put a dmso-mix on and then go on with my day lol, that ended up in stinging pain. Clearly black-dyed underwear got transferred into my before-this Godsend dick.
This is a mess, honestly. These threads made me believe I could beat my Peyronie's and I ended up f*cking with my fertility instead. This is really f*cking with my mental right now
Title: Re: DMSO+X Revisited 2019
Post by: Tom_E on February 10, 2021, 01:35:32 AM
Honestly I have never heard of anyone having a problem with it in that way and trust me, if it ever did affect someones ability to have babies, you would have heard about it from many sources no doubt by now.  That would be HUGE news.
dmso can affect different people in different ways.  some can nearly pickle their dick in the stuff, some paint it all over and some use a tiny bit and get a bad reaction.
I find you dont need a high concentration of it and I only put it on the scar tissue area and only for 15 to 20 min then I tap it dry and leave it on for the night and shower in the morning but it is nearly dry after I pat it dry.  If I use higher concentrations and leave on longer, I cant poop for 5 days LOL.  Thats no fun on the 6th day I tell ya! LOL  trust me, a little goes a long way and it can soak in deeeeeeep. 

I dont think you need to worry.  you probably just burned your skin in a medium way and that sometimes takes a long time to heal.   Your boys down there are probably ok.  You can go for a test to see if you swimmers are ok.

Just chill and use less dmso and only put on the affected area.  be creative with how you can separate your meatballs from your noodle :)
cheers my friend

Title: Re: DMSO+X Revisited 2019
Post by: Tortão Pra Direita on February 10, 2021, 09:59:46 AM
Quote from: Godisreal on February 09, 2021, 08:48:57 PM
Then I remembered months back when I thought it would be okay to put a dmso-mix on and then go on with my day lol,

I don't know if you can put DMSO on your penis and go on with your day...
I could stand a maximum of 10 minutes with DMSO on my penis. It burns really bad (I used, for some days, a cream containing 70% DMSO and 30% aloe vera and it still very strong). I gave up DMSO.

I'm gonna make a cream using Pentravan + Pentoxyfilline (and Curowhite). Maybe I've missed it, but I have not seen people trying to mix pentox + DMSO or another formulation. This seems an interesting idea.

Pentravan is not popular in USA I think cause I haven't seen people here talking about it, but in Brazil urologists recommend pentravan + verapamil.

"Pentravan® is an oil-in-water emulsion base that uses liposomal technology to ensure effective and proven transdermal drug delivery*. Pentravan® is a fragrance-free vanishing cream, providing an elegant skin feel."
https://fagron.com/en/concept/pentravanr#:~:text=Pentravan%C2%AE%20is%20an%20oil,Ready%2Dto%2Duse
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on February 10, 2021, 04:03:35 PM
I appreciate the words there, Tom.
I visited the doc today; but unfortunately, in Sweden, a big chunk of doctors here are from foreign countries because of Sweden's insane migration-politics.
My doc barley understood me and he ended up prescribing me some anti-inflammatory pills (like ibuprofen but stronger). I'm not surprised, however, that he wasn't to any help.
I'll try to remain calm and get through this. Hopefully my ballsack will go back to "normal" sooner rather than later.
God bless you, man.
Title: Re: DMSO+X Revisited 2019
Post by: LuisFernandez on February 10, 2021, 08:54:34 PM
I agree, i highly doubt you did any sort of permanent damage. After burning my skin a bit i just rested for about a week and applied a lot of lotion, aloe vera, and castor oil.

I'm now back to applying DMSO every day.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on February 11, 2021, 06:32:09 PM
Thanks Luis. I did urine and blood test and they didn't see inflammation, but there's no way a poke in the finger can see the inflammation in my penis, is there? Lol, I doubt it.
I'm gonna do a testosterone test in a few weeks as well, to see if the production down there is all right.
It's incredibly energy draining worrying about this as well as Peyronie's.
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on February 20, 2021, 10:31:41 PM
Quote from: Godisreal on December 16, 2020, 09:59:26 AM

The current solution I'm using was originally made the great melting.
It's very sad to see that he hasn't been online for so long because he got banned for some nonsense.
Horrible decision by the admins. He is, without a doubt, one of the most important people in the history of this forum.

Agree, Meltings posts were on point. i Follow his solution as well with Vit C. As for storage, When everything is mixed, I dont think there is an issue with temps. I would avoid Hot rooms. but DMSO alone should not be stored in the fridge or below 65 deg F as it will solidify.

How is your progress? It is cumbersome for me and work. But ive started back up. Stay strong
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on February 20, 2021, 10:39:43 PM
Quote from: Godisreal on December 30, 2020, 08:58:12 PM
Does DMSO react with cotton? 100% cotton-underwear? (white)

That is fine. I personally use Q tips. but any cotton swab applicator will do. for a while I was using paintbrushes with a special brush but got sketched with the metal part that binds the brush to the wooden part.

The book I read that Melting suggested really describes a ton of gold knowledge about DMSO. Its called DMSO: NAtures healer or something like that. I did make a post about DMSO and mentioned the book. Great book and helped me guide my usage.
Title: Re: DMSO+X Revisited 2019
Post by: Holistic on February 20, 2021, 10:56:29 PM
Quote from: Godisreal on January 28, 2021, 07:21:20 AM

I've had scrotum-discomfort since yesterday because I accidentally got some DMSO on my balls while treating my penis. Really fkn annoying, to be honest. 
Would a thick white cloth be okay to place on my balls? To avoid DMSO coming onto my balls?
Or would this react with dmso? I can't find sh*t about this online even after reading 5 full articles about "DMSO, Risks & Uses" etc etc.
What should I do? Please give me some insight, lads, so I can stop having this ridiculous problem.
Thanks

Hard to say where the testicular discomfort is coming from. You could discontinue for a week or so and see what happens with the pain. When I apply my solution it is strictly DMSO, VitC, and castor oil. and it runs all over my balls. I sit on a plain white towel and cover my shaft in the solution. it gets on my balls and the blanket, but I havent had any pain. Ill sit and apply for an hour if i have the time. then wash off after. xanthan shouldnt cause any pain as it is a neutral substance
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on March 05, 2021, 06:09:53 PM
I'm glad that you decided to add that last message, Holistic.
Because, extraordinarily, I'm sitting here a month later with testicular discomfort and weird sensations that goes on every day. Checked with the doc and they've noticed nothing weird (surprise surprise), but hopefully I'll get an appointment for ultra sound as well.
As I might've stated earlier, it started off with a nasty rash which subsided fairly quickly. But I've now noticed a shrinkage of my right testicle; fortunately, I do not care about these things anymore, but it sure is weird.
Not sure if the testicle will remain shrunken or if it will return, but time will tell.
Interesting how you said "it got all over your balls", and you had no adverse effects.
I'm thinking my bad reaction might've been caused by the warm shower water I stepped into after application to wash everything off. My ignorance at its essence, I guess.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on March 07, 2021, 11:33:48 AM
My balls are now the size of peanuts and I can see my skin is still damaged.
This is just a "wow" moment.
How did this sh*t even happened? Not only is my dick crippled, now my sperm-factory is in jeopardy. And why? Because I put faith into DMSO + X?
And I didn't do anything different from anyone else.
F*ck me honestly lol. This is devastating.
Title: Re: DMSO+X Revisited 2019
Post by: Tom_E on March 12, 2021, 12:23:45 AM
Godisreal, testicles can change shape and size for various reasons, but I dont think your balls should shrink like that so do look into it.
Maybe youre more sensitive to certain substances. Also, it could be unrelated to dmso.
Did you do a bunch of Testosterone shots in the past?  that can shrink the boys for awhile. 
If never used Testosterone, then ask doctor to check your hormones, not just T but other things to.  See if the numbers come back normal.
If you have high Cortisol, that can affect Testosterone and other things.  Cortisol s released when people get stressed or for other reasons.  fight or flight kinds of things to.
check into that.  Maybe anaylze your diet more or examine any changes in sleep patterns or if you get too warm sometimes when sleeping late at night...etc.
Let us know how it goes.
Tom
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on March 18, 2021, 06:50:35 AM
Thanks for the message, Tom.
I genuinely do not understand how I'm still in pain and discomfort after almost 2 months.
I just tried to better my condition following basic instructions, and I'm left with more problems.
It's so depressing it's out of this world.
After the application I showered and that triggered another skin reaction with the DMSO, causing a rash that subsided after 2 days.
And yet I'm left with shrinkage and discomfort and I don't even f*cking know why.
It's not like I can tell the docs "Yeah, I put an organic solvent on my balls while trying to better a condition old men get called Peyronie's... that I'm not even diagnosed with" LOL
That last part is not a surprise tho. The docs suck.
But damn, I'm in a deep hole here.
Title: Re: DMSO+X Revisited 2019
Post by: Godisreal on April 23, 2021, 01:18:48 AM
Update regarding DMSO and reproductive toxicity:

My semen is now watery and that is often a sign of low sperm count.
I still have chronic pain in my scrotum 3 months after I got DMSO on my ballsack and then washed it off. For those of you that haven't seen my previous posts in this thread, a major skin-reaction came after washing it off in the shower. This resulted in a nasty rash, and now, 3 months later chronic pain and watery semen.

Absent user @melting used to claim a lot of things about DMSO, for example that DMSO only has one reaction with water (this is false). I would never ever advise anyone to use this on their penis, and near their testicles. My DMSO-solution was very runny so that's why it sipped down a little on my balls back then.
But I still believe it's the skin reaction caused by the warm shower water and the DMSO that has ultimately caused me chronic pain and now watery sperm. There's some kind of chronic damage to my scrotum. It clearly has effected my testicles as well.
There's a possibility that both my testosterone and semen quality have been damaged.
Did an ultrasound on my testicles a few weeks ago, and nothing was wrong, said the doc.
I'm gonna have both my testo-levels and my sperm count checked within the next week to see what's going on. I'm not gonna race to conclusions until then.

There are countless threads of scientists discussing the toxicity of DMSO, as well as how misunderstood it is. Now when I've read about it more, I do not understand how anyone in their right mind would preach and tell people to use an organic solvent on their penis. It's bizarre.
Me as a young man, however, often listens to older people because I believe they have more wisdom; and that's often true, but not always.

I'm typing this so people don't make the same mistake I did.
It is of course my fault that I trusted the well made threads and explanations on the forum, and chose not to make extensive research regarding DMSO's toxicity.
I guess I did what everybody else did, but yet I'm the only one with this issue.
There's clear evidence that organic solvents has a very negative impact on male fertility, and there's literally evidence that DMSO causes clear cell toxicity at a certain point.
And yet, the man who preached about this didn't include one single warning regarding these things.
He did say "be careful", but everyone is. Especially me.

Sorry if this all comes off as ranting, but I'm just warning all the young people out there to:

stick with the proven treatments and DO NOT experiment with the most important organs on your body.

This entire post is nonsense as are Gir's prior posts in this and many other topics.Administrator
Title: Re: DMSO+X Revisited 2019
Post by: Hawk on April 23, 2021, 09:10:25 AM
Gir,  Your last post is full of bizarre non-sense based on nothing but the speculation of an inexperienced young man with no training or professional background and a refusal to document anything you say.  I am becoming concerned your issues are more body dysmorphia or other psychological issues.

You repeatedly make absurd statements on this forum on every topic, and you do so as though you have some clue what you are talking about.  You never state your outlandish speculation as a question or even as an opinion but as established fact. 

I have warned you before that we are not providing a forum for such nonsense.  You are so out of touch on your posts, that out of twenty thousand members, you are only about the 4th member in sixteen years that is on the verge of being sanctioned for such behavior.

I am NOT a proponent for DMSO for Peyronies Disease, but I have years of experience with it since it is a substance approved by the very restrictive FDA in the U.S.   It is also approved in most other countries for both human use and veterinary care.  I have used it to deliver antibiotics into the infected foot of birds of prey. It is well established for such use by many leading animal science centers of excellence.  It is a component of many prescriptions and even some OTC preparations for humans to deliver NSAIDs and other substances.

DMSO dissolves many other substances (definition of a solvent), and it can transport other substances with a low molecular weight .  It will, for instance, transport penicillin, but it will NOT transport insulin.  There is nothing scary about the word solvent.  Water is classified as an excellent solvent.

It is a naturally occurring compound and is produced in nature in the atmosphere.  It occurs in small quantities in tomato paste, sauerkraut, and other foods.  It can be applied on the skin, taken orally, or by IV with very low toxicity rates.  You would need to take pounds of it to be toxic, and there is no way to absorb that through the skin.

It is important to apply it to clean skin since it can transport some substances on the skin if they have a low molecular weight that can pass the skin barrier.

A one-time dribble of DMSO on your scrotum can't have any effect on your semen, much less a lasting effect.  If you are soaking your scrotum in a bowl of DMSO  for hours a day, please discontinue (even though evidence suggests it would be safe).

I have stated this as fact.  Therefore I have an obligation to document my facts.  Unless you learn to do the same, you will soon be placed in a forum group that publicly labels you as an unreliable source of information in your signature line on all posts and PM.  It will also restrict you from altering your profile, posting on the introduction board for new members, and other restrictions. Any attempt to bypass those restrictions will result in a permanent ban and the potential deletion of your posts.

Consider this your LAST informal warning

https://pubmed.ncbi.nlm.nih.gov/3916302/
https://www.gaylordchemical.com/environmental-health-safety/dmso-health-safety/
Title: Re: DMSO+X Revisited 2019
Post by: ben12 on August 09, 2021, 03:04:33 PM
Does anyone actually know the specific measurements you put in the X parts...

Like how much Vit C to use, how much Vit E? How many drops of iodine? etc...

Title: Re: DMSO+X Revisited 2019
Post by: Anbil on August 12, 2021, 10:00:05 PM
I'm compounding a cream currently of 15% verapamil 10% pentoxy 10% DMSO in a liposomal base.

I'm wondering if DMSO can actually penetrate through the skin and fascia into the albuginea.

I'm also wondering what the right concetrations of the above drugs should be, as well as if I should add any other ones.

Other I am considering is tranilast which has been used in scar creams. Wondering if anyone has experience in this or has done something similar.
Title: Re: DMSO+X Revisited 2019
Post by: Lostandsad on August 18, 2021, 08:37:56 PM
Anbil, have you had any success with your DMSO mixtures?

Has anyone here tried DMSO + ascorbic acid? That seemed like melting's bread and butter and the highest probability of working, in theory. I wonder where melting is. I hope he's as close to a cure for his own peyronie's and moved on
Title: Re: DMSO+X Revisited 2019
Post by: projectpd on August 23, 2021, 04:31:46 PM
If you simply mix the drugs into an existing liposomal base, they won't be encapsulated, that being said, maybe in some cases it doesn't matter, see https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125578/
To make your own liposomes you can try using a sonic cleaner bath (very cheap from China) or probe. (Again there is a Chinese one , they have a higher frequency than the baths so might be better) fir example There are recipes on the web for vitamin c liposomes, which basically involves sonicating a solution with lecithin, and maybe some additional agents. As the link suggests though, it may or may not be advantageous! Liposomes are not in typical creams/gels/emulsions, they are much smaller particles of about 200 nm or less.
Title: Re: DMSO+X Revisited 2019
Post by: Fix This on October 11, 2021, 06:13:42 AM
Hi all

I haven't posted on this thread for a while

I was just reading a couple of other thread reagrding possibe oral medications and combinations that seemed to have had some results

One is Tamoxifen taken with a PDE5 inhibitor ( I use cialis 5mg ). Studies have suggested it's efficiacy and this user appears to have had a complete straightening of his penis using these ( along with traction )
https://www.peyroniesforum.net/index.php/topic,13988.msg146443.html#msg146443

There is also a user who appears to have had complete strightening using a Biocell product which is a combination of Type 2 Collagen, Hyaluronic Acid and Chondroitin
https://www.peyroniesforum.net/index.php/topic,16392.msg144307.html#msg144307

Has anyone tried using DMSO with Tamoxifen ? Or indeed with a Biocell product ( there are many under different labels it seems )

DIM (Diindolylmethane) is another product which this user has observed has similar effects to Tamoxifen, and is available without prescription
https://www.peyroniesforum.net/index.php/topic,16533.msg146444.html#msg146444

So basically, these are 3 options that I am considering as oral treatment at the moment.But further research is required, and availability of Tamoxifen could be a challenge for me in the UK without prescription

There are know side effects with Tamoxifen, which would make me a bit cautious about taking. But if it was to be used topically using DMSO then I would think that the effect on the entire body would be considerable less, plus it would hve the usual DMSO advantage of targeting the plaques and peyronies directly

Thoughts anyone ?






Title: Re: DMSO+X Revisited 2019
Post by: DT22 on December 20, 2021, 07:01:22 PM
If I have this stuff, do I have to dilute in water or is it fine to rub onto my plaque?

https://www.vitamart.ca/life-choice-dmso-gel-100g?gclid=Cj0KCQiA8ICOBhDmARIsAEGI6o2DAIgdaYNokjZekOvEIb_zKU5yXsfxVBr0hLIjt4pPQCngDL9d7eoaAmwMEALw_wcB
Title: Re: DMSO+X Revisited 2019
Post by: projectpd on December 21, 2021, 04:30:09 PM
90 % is very high.  It might be irritating . Are you targeting any particular substance for transdermal delivery? Studies suggest different concentrations are more effective for different substances, it has various modes of action at different concentrations.
Title: Re: DMSO+X Revisited 2019
Post by: Whyisthishappening on August 03, 2022, 07:47:20 AM
i am on week 3 of DMSO+ Vit C so far nice improvement in pain(no pain at all ).I also GAINED 0.5 CM IN LENGTH


i also experimented with generic DMSO+ALOE VERA for 3 days .DO NOT USE THIS its not good for deformities(makes them worse) but still good for pain.


I use DMSO+Vit C constantly all day ,more than 10 times a day
Title: Re: DMSO+X Revisited 2019
Post by: pey ron on August 15, 2022, 01:04:18 AM
15% verapamil 10% pentoxy 10% DMSO in a liposomal base???

from a quick look, pentox is only soluble at 1% in DMSO or DMF, 5.5%-7.7% in water, 0.2% in ethanol
Title: Re: DMSO+X Revisited 2019
Post by: YoungPrince on September 07, 2022, 06:41:08 AM
Just made and used dmso + vit c on my arms....it didnt go very well, got a very serious swelling with a small redish circle, it seems cold pack helped get it down but not entirely yet.

I used 100ml dmso, 10ml boiled water, vit c, lecithin,xantan, castor oil.

I used two ceramy cup but, both used for drinking purposes, so it was quite foolish, i am in bad state and quickly getting worse so i tried to haste things.
Also didnt notice that the wooden chopstick that i used to mix have "gel" on it instead of simple wood. Despite these flaws the outcome was pretty gel like so i still proud of that.

I looking for advice from anybody who got some success with dmso.
Title: Re: DMSO+X Revisited 2019
Post by: YoungPrince on September 09, 2022, 10:44:51 AM
I would like to advise some cauction for every member who want to go on an experiment. It seems my cream gave me thrombosis, not sure yet but there is a chance.
The pain intensity is vary but didnt subside, instead, started moving up on my arm. Just a warning for everyone.
Title: Re: DMSO+X Revisited 2019
Post by: YoungPrince on September 18, 2022, 09:13:27 AM
Eventually it subsided. Does anyone experienced similar?
After applying a few drop on my hand i feel my arm a bit tense especially around the inner part of my elbow.
Title: Re: DMSO+X Revisited 2019
Post by: overthecurve on March 27, 2023, 09:40:59 AM
***STOP whatever you're doing and read this***

DONT WAIT FOR YOUR CONDITION TO WORSEN BEFORE YOU START

Improvements in 7 days of use ( Imagine in a year !!!)

- Nocturnal erections are back and stronger than ever (from day one of use)
- Ejaculation/sperm load increased (triple in my case)
- Harder erections, hard glans
- Tissue softening, I can put my penis 100% straight at a 90% erection, felt within 24 hours of use
- Less contracted, more blood circulation, warm feeling instead of cold
- Looking a lot nicer while flaccid
- Girth increase
- Narrowing reversing
- Curve improving
- Length increased flaccid and erect
- No more hard flaccid symptoms
- Not the everyday feeling of symptoms getting worse
- Distress feeling relief, light at the end of tunnel feeling, depression symptoms lowering, confidence exploding

My DMSO diary (AND PROGRESS)

Cause of Peyronies Disease/fibrosis suspected:

- Unhealthy masturbartion habit
- Jelquing
- Bathmate pump abuse (?!)
- Prone to immune diseases

Symptoms:

- 35-40 degree leftward and upward curve for about 3 years (no hard plaque, just fibrosis)
Some twisting
- Fibrosis all along the shaft, left side seems obstructed or not as full as of the right side, even flaccid can be felt, keep worsening
- Narrowing at the base and under the glans, Hourglassing, keep worsening
- Penis always very contracted, light weight, bloodless
- Extreme loss of girth (which is the most concerning for me)
- Flat shaft sensation
- Cord on top of the entire shaft, penis not flexible at all
- No more or very few and weak nocturnal erections for about a year
- I don't feel my penis when it is flaccid
- glans remain soft when erect
- I have most of the HF symptoms (pubic, groin and perianal pain, penile and testicule pain, pain after
  ejactulation, etc)
- I almost don't have sperm anymore, dry orgasm

Why starting DMSO:

- I discovered its existence on the forum and read about it for hours. I read the available medical literature and a book about it. It seems that's it is not studied enough and could possibly be something working.
- I tried just about everything and no success, my last resort before surgery
- Im desperate

What treatment I did or was currently already doing before DMSO :


- Colchicine : too toxic, no effect I stopped
- Oral Vitamine E :everyones knows it doesn't do crap
- PRP : Snake oil, worked for a week
- Traction with PMP : Initially, the first 6 months It was incredible, my girth doubled, the size increased and the curve was not bothering me anymore because my penis was so big and hanging. When I met someone, I started to use it less and the effect subsided and I started to see my symptoms worsening, thinning started and curve became worse. I stopped its use for a couple months and then started again and I could never attain the same results as used to have. (Im not using it right now)
- Traction with restorex: Bought it after PMP, definitely worsened my condition and created narrowing all around the glans. (Stopped it)
- Cialis 5mg daily for a year (still doing it)
- Bath mate pump: Its only temporary results but make me less ashamed with my extremely
narrowed dick. I had it for many years, probably one of the cause of my fibrosis (still do it but more carefully) Im thinking about a VED to replace it.
Gluten free diet for 2 years, no real changes on my dick, but I like the general effect on my body and mind. (Still doing it)
- Some physiotherapy for pelvic floor which is helpful for HF symptoms. (Ill go back as soon as I have money)
Meditation, mental wellness, personal growth reading (these were the remedies that helped the most so far, not for the curve but to avoid going crazy).


DMSO Recipes (If you have Peyronies Disease with calcified plaques you should consider other ''+X'' that have effect on calcium deposits)

Recipe A : DMSO (9:1) (about a tea spoon) +  H2o (1:10) (half tea spoon) + xanthan + castor oil (2-3 drops)
Recipe B : DMSO + H2o + turmeric (oil soluble) + castor oil or black seed oil

***Recipe C : DMSO + h2o + absorbic acid + Castor oil + xanthan

Recipe D : DMSO + Nigella Sativa (black seed oil)
Recipe E:  DMSO + CBD tincture

***Recipe F:

 [DMSO + H2o (3:1)] + Black seed oil (few drops) + hyaluronic acid and vitamine B                                              complex + fish oil (1 capsule) + xanthan gum (a pinch).


Day 1:

- I applied recipe A on my forearm to test my reaction to this concentration of DMSO. No burning, nothing.
- I applied the solution on my penis, same reaction
- I Applied recipe B right after sexual intercourse: Normally I am in pain, groin pain, penile pain. This time I felt relief, no pain at all. Is it placebo? Can't say right now. Is it the turmeric added or is it the anti inflammatory properties of the DMSO itself?  I re applied the recipe before going to bed.

Day 2:

- I woke up with a boner for the first time in about a year. I had to wait to pee, and that did not happen in a long time.
- applied recipe B at wake up
- applied recipe C after bath
- I went to the gym and after my penis is usually very contracted, I felt today it was more hanging. Fuller in blood. I started oral supplement of L-arginine so it could be that also.
- 3rd time recipe C at noon. Still no burning, I always apply castor oil after I washed the solution.
- 4th time: Recipe C 3 pm
- 5th time:  Recipe B 10 pm, still no burn/redness

Day 3

- Waking up to hard rock boner. When it goes down, as soon as I manipulate my penis to apply my solution, it becomes hard again. Encouraging, I thought it was dead.
- Recipe C : first thing waking up
- Recipe C : before Lunch
- Recipe C : After Lunch
- Recipe C : night
- Recipe C Before bed
- Observation of the day : my dick is a lot softer, it's squishy, hanging. Flaccid looks nicer, smoother skin, I feel my penis in my pants. Since I noticed the results from day 1, I am assuming that it is the effect of the DMSO itself not the ''+ X''. Another thing I observed is that usually because of my curve, when I pee my stream tends to go left, be uncontrollable or weak and today I noticed that I have a strong stream that goes right where I want. I can't obviously see changes yet in my curvature, but I really feel a change is happening and I hope it is permanent.

Day 4

- Boner. All. night. long. Im now nervous in the morning to see if I wake up with a boner, every day he's getting harder. Feels more squishy. This is subjective, but girth seems to be increasing
- I can't believe what I see in the mirror. My flaccid penis looks straight or I can put it straight because it is so flexible. Something that bothers me a lot is that my penis is so stiff that in my underwear it does not have a round shape, it's like a hard cord, I don't know how to explain, but it is ugly. But today, my penis is roundish, and the effect in my underwear is already visible. Placebo or not, subjective or not, Ive never felt, in the last 2 years, something so effective, something you can see results after 4 days. I should have discovered this before. I think Peyronies Disease can't happen if you applied this right after a trauma!
- Recipe B at wake up : Note that I used to let the product for 5 mins, I now leave it for 20 min.
- FROM SUBJECTIVE TO OBJECTIVE: As I was getting an erection and felt my dick bigger in my hands, I decided to take pictures of my progress, so I could see the evolution in the long term. I can't stop looking at the pictures. My penis is actually bigger, narrowing is reversing and curve is less stiff. It's unbelievable, just for the progress Ive got so far, I call this thing a miracle! Even it it's stop there, It's the best thing that happened to me.
- I just masturbated, I had A CUM LOAD !!!!!! It has been years since I did not have more than a drop!!!! It went on my shirt and this is spectacular! This can't be placebo...
Penis size has definitely increased. Since its back to a great size, I don't think Ill do traction anymore since im pretty sure it injured my penis. I will do some soft manual traction from now on.
- My penis is very warm, it feels good, not inflamed.
- I spent the entire day in front of the mirror....My penis looks normal, it does not hurt....
- I applied recipe B 2 times and Recipe C 5 times
- I burnt myself. I applied Biacitin ointment and castor oil and in minutes it improved.


Day 5

- Did not wake up with a boner, I guess it doesn't happen everyday, but my dick was still full of blood and squishy. I am no doctor, but I think what happens to our dick is oxydation stress: our dick becomes deprived from nutrients, oxygen and hydration and it makes our penis age very quickly. What DMSO seems to do is to fill all vessels with blood and delivers nutrients/drugs.
- Now every time I apply the solution, I burn myself. My skin is already saturated with the recipe so Ill make a new one today with more dilution
- Meanwhile I put the recipe on my perianal region and pubic area, Im hoping the vasodilatation effect will be felt in the shaft or will help relief the tense areas around it
Top of my shaft gets more blood when erect and my glans become fully hard now when I have erection.

Day 6

- Boner waking up. I used to wake up to a contracted, small and flat, bloodless and lightweight dick with a desperate feeling everyday. Now for a week I wake up to the big and juicy penis and it is very encouraging, starts the day a lot better.
- I was thinking about circumcision and a STAGE surgery for next year, now I don't want no surgery to my member. I see progress naturally and there is now hope like I never had before
- The skin is getting irritated and wrinkly. Im not worried because I read about it and Im a bit agressive with the treatment. I put Baciticin ointment, castor oil and hylaluronic acid to re hydrate and prevent burning. I feel no pain at all after I apply these.
- I started a more diluted solution and a new recipe (F) which is so far the one that absorbs the quickest.
- I have no more pain at all, no more hard flaccid symptoms, it's like Im already used to it.
The narrowed spots on my dick seem to fill up in blood more than usually
- I put the recipe F 5-6 times.

Day 7

- waking up with a boner is now the normal.
- I stopped using the recipe with turmeric because staining is too annoying
- My routine will now be alternate between Recipe C one day and Recipe F the other day, 1 week of every 2 months, I will do it for 1 year
- At this point the biggest changes have happened and the next weeks will probably be more subtil, but I if see any major changes I will come post them.


Please don't expect me to come reply everyday.
Title: Re: DMSO+X Revisited 2019
Post by: Sonic on March 27, 2023, 12:14:08 PM
Quote from: overthecurve on March 27, 2023, 09:40:59 AM***STOP whatever you're doing and read this***

Is there a possibility you could upload any pics of your current state? I have seen pics from you in another thread of your Peyronies so it would be nice to compare.
Title: Re: DMSO+X Revisited 2019
Post by: overthecurve on March 27, 2023, 07:47:01 PM

I used to know how, seems I can't find it anymore. Do you know how ?
Title: Re: DMSO+X Revisited 2019
Post by: Sonic on March 27, 2023, 07:51:53 PM

I think you can upload to sites like imgur for example and then just post the links to the pics on here. Or there is some other easier way that some other member knows.
Title: Re: DMSO+X Revisited 2019
Post by: overthecurve on March 28, 2023, 08:18:19 AM

I don't think for now I am ready to upload them to the internet unless there is a direct way to put it on here. Keep in mind that it is a 1 week progress so the changes are more felt than visible. Still though, on the pics you can see a healthier penis, more girth at the narrowed places, glans fuller in blood (and more pink), a we can notice it is a bit straighter (probably because more blood fills in) and smoother. I will keep taking pictures so we might see better in a couple weeks. Hopefully it will keep improving.

Today's observation: When i used to masturbate, it would hurt or be very hard feeling on the penis. Im not use if it is the addition of hyaluronic acid or the continuous use of DMSO for a week, but now my penis is squishy even when erect. I really feel it is a penis, not a bone!!

My biggest wish it is that it will become permanent and that it will keep progressing and that this is not the end result.
Title: Re: DMSO+X Revisited 2019
Post by: olowshinenine on June 22, 2023, 01:20:01 PM
Wow. Just finished reading this entire thread. Melting paved the way with some very interesting prospect for this DMSO solution. Godisreal how are you doing? Did your scrotum stop hurting? It sounds like your solution might have too much DMSO in it maybe it needed more water? Also Melting said it needs to react with water first or it will react with the water in your body.

Sounds like DMSO is definitely messy but even the FDA says its safe. Has anyone just tried applying the DMSO alone to their penis on a regular basis?

Then slowly adding other chemicals / nutrients to it one by one?

I think I might try this first.
Title: Re: DMSO+X Revisited 2019
Post by: LWillisjr on June 27, 2023, 07:18:44 PM
Quote from: olowshinenine on June 22, 2023, 01:20:01 PMGodisreal how are you doing? Did your scrotum stop hurting? It sounds like your solution might have too much DMSO in it maybe it needed more water? Also Melting said it needs to react with water first or it will react with the water in your body.


Don't expect a response, he hasn't been on since August of 2021.
Title: Re: DMSO+X Revisited 2019
Post by: olowshinenine on July 09, 2023, 12:28:01 AM

Thanks for pointing that out. I am considering DMSO with serrapeptase but have not made the leap yet. It would be great to hear if anyone else has had success
Title: Re: DMSO+X Revisited 2019
Post by: Mr man on September 21, 2023, 10:03:07 AM
Quote from: melting on October 23, 2019, 11:52:43 AMAlright, I experimented a bit..


Mixing Castor oil with some Xanthan and Lecithin.



I used organic liquid castile soap. As a emulsifier. Adding about 5g to a 55g DMSO mixture. Into a sealed jar and shakes vigorously. There was a lot of foam. Worked fine though.

It absorbed into the skin in about 20 min.

Am checking for adverse reactions. It's been about 35 mins. Nothing bad so far.
Title: Re: DMSO+X Revisited 2019
Post by: McLovin on September 29, 2023, 10:21:24 AM
Not sure if this is the proper thread for my question, but it looks as closely related as any. I'll probably start a new thread as well.  First of all, what is DMSO?  SOrry, i see it mentioned a thousand times on this forum but it's never explained what that even stands for!
My real question is does anybody know if the plaque and/or scar tissue from Peyronies is linked to similar plaque or calcifcation in other parts of the body? Other than possible trauma to the penis, which I'm pretty sure I did not suffer from, I'm not seeing any other known reason for why Peyronies occurs.  The reason I ask is because I have noticed a handful of what I would call calcium deposits in other parts of my body, mainly my appendages.  Similar hard spots in my fingers, the palm of my hands, and I can feel one on the ball of my foot.  And they all have appeared roughly the same point in my life.  I can't pinpoint exact times when I noticed them, the one in my hand was definitely there before my Peyronies, but all of them showed up after I turned 40.  Also, I am experiencing new unexplained joint pain, and have developed fluid build up on my knees for no apparent reason.  Meaning I haven't had any specific injuries to cause it.  I can't afford a dr. right now  (F**ck You American healthcare system!) so I'm trying to do some research on my own to see if there is an underlying cause for all of this.  Has anybody else noticed other types of calcium deposits (that's what I call them, not sure what the proper term is) in other parts of your body?  I saw a video where a guy had a large calcium deposit on the back of his hand and they just smashed it with a large book, maybe that's what I should try with my Peyronies! lol I've been so frustrated with it that sometimes it doesn't sound like a bad idea!
Title: Re: DMSO+X Revisited 2019
Post by: Mr man on October 17, 2023, 02:27:06 AM
Just to add. Have been using the thacket formula. Plus vit c and Magnesium. Mixed as instructed by melting. I slap it on generously. At bedtime before sleep. Leave penis exposed for about 20 minutes. Then repeat. I finish off wearing a non toxic food bag. (made from plant material). Over penis. Go to sleep. Let it sink in overnight.

By the second application. There is a mild pain on the plaques. It's more of a feeling then pain. Something is happening.

Penis gets washed in the morning.

Before application. I have a 20 minutes vacuam therapy session. For penis modalling. Using electric pump.

It's too early to post any results yet. I intend to do this for 3 month. Before measuring results.

Am on day 12.
Title: Re: DMSO+X Revisited 2019
Post by: Mr man on October 21, 2023, 02:37:32 PM
Quote from: McLovin on September 29, 2023, 10:21:24 AM, what is DMSO?  I would call calcium deposits in other parts of my body, mainly my appendages.  Similar hard spots in my fingers, the palm of my hands, and I can feel one on the ball of my foot.  And they all have appeared roughly the same point in my life.  I can't pinpoint exact times when I noticed them, the one in my hand was definitely there before my Peyronies, but all of them showed up after I turned 40.  Also, I am experiencing new unexplained joint pain, and have developed fluid build up on my knees for no apparent reason.  Meaning I haven't had any specific injuries to cause it.  I can't afford a dr. right now  (F**ck You American healthcare system!) so I'm trying to do some research on my own to see if there is an underlying cause for all of this.  Has anybody else noticed other types of calcium deposits (that's what I call them, not sure what the proper term is) in other parts of your body?

DMSO is dimethyl sulfoxide. It's a non toxic solvent. That absorbs into the body. It transports medication mixed with it deep into tissue.

Dude, can't you use emergency room? Having deposits all over your body. Your condition could be serious.

Title: Re: DMSO+X Revisited 2019
Post by: McLovin on October 23, 2023, 06:17:50 PM
lol do you have any idea what an ER visit costs without health insurance in America?  Me either, but I know it's a lot and I don't plan on going unless I'm pretty sure I'm dying.  Thank you for the DMSO clarification, that's something I probably should have already known lol
Title: Re: DMSO+X Revisited 2019
Post by: Mr man on November 01, 2023, 10:07:55 AM
Mclovin, am just concerned about your symptoms. 'calcium deposits' on your digits sounds bizarre. Hopefully they will clear up on there own?

The US has a commercial health system. It's a shame for the general population. I digresse.

All the best.

Title: Re: DMSO+X Revisited 2019
Post by: Bilhardas on November 23, 2023, 09:22:46 AM
I use only DMSO + castor oil together, why the need to mix it in advance when you can just put both together on your dick and mix it?  I see here so many mixs that makes no sense in my opinion
Title: Re: DMSO+X Revisited 2019
Post by: Lucky12 on December 11, 2023, 03:58:05 PM
Quote from: Mr man on October 17, 2023, 02:27:06 AMJust to add. Have been using the thacket formula. Plus vit c and Magnesium. Mixed as instructed by melting. I slap it on generously. At bedtime before sleep. Leave penis exposed for about 20 minutes. Then repeat. I finish off wearing a non toxic food bag. (made from plant material). Over penis. Go to sleep. Let it sink in overnight.

By the second application. There is a mild pain on the plaques. It's more of a feeling then pain. Something is happening.

Penis gets washed in the morning.

Before application. I have a 20 minutes vacuam therapy session. For penis modalling. Using electric pump.

It's too early to post any results yet. I intend to do this for 3 month. Before measuring results.

Am on day 12.
Quote from: Mr man on November 01, 2023, 10:07:55 AMMclovin, am just concerned about your symptoms. 'calcium deposits' on your digits sounds bizarre. Hopefully they will clear up on there own?

The US has a commercial health system. It's a shame for the general population. I digresse.

All the best.



Have you gotten any positive result from dsmo . I'm still waiting for your update
Title: Re: DMSO+X Revisited 2019
Post by: McLovin on December 18, 2023, 06:23:40 PM
Quote from: Mr man on November 01, 2023, 10:07:55 AMMclovin, am just concerned about your symptoms. 'calcium deposits' on your digits sounds bizarre. Hopefully they will clear up on there own?

The US has a commercial health system. It's a shame for the general population. I digresse.

All the best.
Appreciate the concern.
Just to update.  I am attempting to get into a men's health clinic but the process is slow.  Doesn't help that I live in the absolute middle of nowhere.  I am still curious about the other deposits in my body. Since I first posted about this, I now have another mass on the right side of penis, a small painful lump on my neck, and today a terribly painful, similarly sized lump on my head, just behind my right ear.  It might all be coincidence and non related to my Peyronies in any way, but the timing, along with all of the similarities in size, the way they feel, and pain in them seems like it's at least worth looking into.  Or maybe I'm about to drop over dead and I won't have to worry about this crap anymore.

Title: Re: DMSO+X Revisited 2019
Post by: Legacy on December 24, 2023, 11:59:30 AM
Any positive results to update us with?
Title: Re: DMSO+X Revisited 2019
Post by: happyman on February 18, 2024, 04:07:54 PM
Hey this is an awesome post. thank you for sharing
Title: Re: DMSO+X Revisited 2019
Post by: raugustofer on March 08, 2024, 04:49:08 AM
DMSO is giving me GREAT results...

Hi, guys, I am from Brazil and have been through this crap for 4/5 years. I propably had a sex incindent. I lost about 6 cms in lenght and a lot of girth. Didnt even feel like a man anymore.

At first I tried
- pentox and coenzime10
- shock wave therapy (2 rounds of 6 sessions throughout a year and only made my plaques disapear. No size gain)
- ved, extensor
- and a PAPAYA extract(or papain, I dont know what would be the correct translation) cream i found online that was said to treat peyronies.

Nothing really worked for me until I got into this post. I was in despair and willing to try it all.

I followed the tutorial that melting posted around page 3/4 with dmso, vit c and castor oil. At first it was a lot of work. But after you prepare the solution twice it gets easy.

I started apllying 3 times a day december 2023 and using extender 45/1h daily.
3/4 months of treatment and I have gained 3 cms and a lot of girth. Feeling much more confidence at sexual life now.

In comparison (I never had the nerve to measure): after peyronies my penis was smaller the my iphone 11 the time. Now it is the sizer of my iphone14 pro max.

1 month ago, since the dmso brings the properties deep into the scar tissue, I decided to try to apply the PAPAYA EXTRACT right before I aplly DMSO.

I dont know if the extract is helping or the DMSO is doing the work alone. But I will keep apllying both of them for a few more months and will be back with more updates.

PAPAYA (papain) CREAM AS I HAD MADE FOR ME:

-Papaina 2% (guys, look for the right term for this)
-Hialuronidase 600 utr (hyaluronidase)
-Vit E 0,5%
-Cream qsq 50g (I guess this is what they use to make it into a cream)

Soon I will bring more updates. Sorry for bad english.
Title: Re: DMSO+X Revisited 2019
Post by: happyman on March 10, 2024, 02:09:38 PM
What is the latest dmso + x people have been using with good results?

I would imagine adding something like serrapeptase would help significantly?
Title: Re: DMSO+X Revisited 2019
Post by: Scizor on March 15, 2024, 09:57:04 AM
Quote from: raugustofer on March 08, 2024, 04:49:08 AMDMSO is giving me GREAT results...

Great to hear that, keep us posted! ;)
Title: Re: DMSO+X Revisited 2019
Post by: xfan on March 18, 2024, 12:53:34 PM
Any improvement in curvature? If so by how many degrees?

Quote from: raugustofer on March 08, 2024, 04:49:08 AMDMSO is giving me GREAT results...

Edited by Admin- please read rule number 7 on quoting

https://www.peyroniesforum.net/index.php/topic,6.0.html
Title: Re: DMSO+X Revisited 2019
Post by: raugustofer on March 19, 2024, 04:56:48 PM
I didn't have any curvature issue. I just lost length and girth...

I keep aplying the treatment as above and continue to seeing results. 


Quote from: xfan on March 18, 2024, 12:53:34 PMAny improvement in curvature? If so by how many degrees?

Edited by Admin- please read rule number 7 on quoting

https://www.peyroniesforum.net/index.php/topic,6.0.html