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Peyronies Disease TREATMENT Discussion Boards => Oral Treatments for Peyronie's Disease => Topic started by: Michiganguy19 on August 02, 2019, 03:09:42 PM

Title: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Michiganguy19 on August 02, 2019, 03:09:42 PM
I am on my 3rd day starting this treatment. Below is a link to a single study showing this treatment resolved peyronies disease completely in 8 months. Only one study to go off of and the cyclophosphamide has extreme side effects including hair loss. I have nothing to lose at this point so I am giving it a shot and will keep you updated if this actually works at all. Cyclophosphamide has been shown to break down and stop scar tissue from forming in a few different diseases including pulmonary fibrosis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037975/
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Patientxyz1992 on August 02, 2019, 03:59:11 PM
Man ill be folowing your updates ad if even remotely helps i will consider using it, i would care less abaout the hair, thank you very much! Btw there are so manny treatmants in development like peptides and stuff who promote angiogenesis etc that i dont know where to look for.....and why arent they on market...
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: samsung on August 02, 2019, 05:37:52 PM
Please keep us all updated. And stay safe. Those drugs sound like serious stuff.
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: skunkworks on August 03, 2019, 02:26:12 AM
Is this being monitored by a doctor?
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Werther on August 03, 2019, 02:51:55 AM
How did you get these things prescribed?

Was it a urologist?
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: samsung on August 03, 2019, 09:32:40 AM
In my participation in this thread I hope it is not mistaken that I advocate taking this course of action. Without doctor supervision this is very dangerous. All I meant to say was, stay safe. Nobody on this forum would recommend doing this without the supervision of a physician.
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Michiganguy19 on August 04, 2019, 10:47:55 PM
To be quite honest it is not from the supervision of a doctor. I called a pharmacy in another country and ordered it. Then confirmed with a friend that is a pharmacist that I got legitimate cyclophosphamide.
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Michiganguy19 on August 04, 2019, 10:51:33 PM
I also am taking the dexamethasone twice a week
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: skunkworks on August 05, 2019, 09:33:58 AM
Pharmacists don't tend to have the equipment or skill to identify unknown substances... H-NMR, HPLC, Mass spec?

To be clear, I think this is a very bad idea. Dose is VERY important with cyclophosphamide, equally important is close monitoring.
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: samsung on August 11, 2019, 02:15:54 PM
Any updates for us Michiganguy? We all hope you are o.k.  Please check in.
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Michiganguy19 on August 13, 2019, 02:07:08 AM
13 days in, no change. Cyclophosphamide supposedly takes 6 weeks to begin working in the body. So I will update then.
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Michiganguy19 on August 13, 2019, 02:10:56 AM
Saw the best urologist supposedly in the state of Michigan for Peyronies, Dana Ohl at U of M. Said even though I'm as bad as I am he won't consider surgery until my penis is half the size it was before. I was 7.2 before now 6.1. That seems ridiculous to me cause flaccid I am embarrassingly f'~c<+d now. Said he's seen worse at count myself lucky I was the most mild case of the day. And he said to stay off this forum cause people give wrong info and he hates this forum it's just a bad idea lol
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: skunkworks on August 13, 2019, 07:51:19 AM
Yeah because most of them see surgery as the only option. Sad truth, they have a hammer so all they see is nails.
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: jj21 on August 15, 2019, 06:43:46 AM
Really interested in this. Keep us updated.
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Hontas on August 15, 2019, 09:14:16 PM
Urologist are the dumbest of all sadly. I have a theory that they take in only the ones that performed worst overall in medicine masters test. Dont go to urologists, find yourself a smart rheumatologist. That is my experience 13/15. I found only two decent urologists both of whom offered me nothing instead of acting like the c*nts the other 13 urologists are
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Michiganguy19 on August 16, 2019, 06:32:50 PM
Quote from: Hontas on August 15, 2019, 09:14:16 PM
Urologist are the dumbest of all sadly. I have a theory that they take in only the ones that performed worst overall in medicine masters test. Dont go to urologists, find yourself a smart rheumatologist. That is my experience 13/15. I found only two decent urologists both of whom offered me nothing instead of acting like the c*nts the other 13 urologists are

What did the rheumatologist do for you?
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: samsung on September 04, 2019, 01:54:23 PM
Any updates Michigan? Worried about you. Please check in and let us know.
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: jj21 on September 05, 2019, 11:07:32 PM
Really interested in any update and what the side effects are like?

I'm also interested in trying this.
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: peter123 on October 02, 2020, 11:28:06 AM
Quote from: Michiganguy19 on August 13, 2019, 02:10:56 AM
Saw the best urologist supposedly in the state of Michigan for Peyronies, Dana Ohl at U of M. Said even though I'm as bad as I am he won't consider surgery until my penis is half the size it was before. I was 7.2 before now 6.1. That seems ridiculous to me cause flaccid I am embarrassingly f'~c<+d now. Said he's seen worse at count myself lucky I was the most mild case of the day. And he said to stay off this forum cause people give wrong info and he hates this forum it's just a bad idea lol

why do you make up so much crap? who would believe that a dr saud sucj a ridiculud thibg?
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: TWalker on April 03, 2021, 08:25:52 PM
Any update Michiganguy19?

Very curious to hear how the rather experimental treatment went! Or if anyone else has tried something similar with either of the two drugs?
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Graggaxy on April 04, 2021, 09:16:23 AM
How come no one is trying this out? This is the first time I've seen Peyronie's getting cured
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Godisreal on April 04, 2021, 10:52:57 AM
Because there's barely any logic. And it's difficult to get your hands on it.
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: TWalker on April 04, 2021, 11:03:19 AM
I'd say almost impossible to get your hands on...

But there's definitely a huge amount of logic in taking oral steroids such as dexamethasone during the acute phase to reduce inflammation. Whether it works for Peyronie's or not is another question entirely!
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Curvekiller94 on April 08, 2021, 03:12:54 PM
Any results @michiganguy??
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Seattleman on February 14, 2024, 01:00:26 PM
@Michiganguy19 did you get any results? please update whether good or bad.
Title: Re: Treatment with 50mg cyclophosphamide daily and 5mg dexamethasone twice weekly
Post by: Arthur on March 16, 2024, 02:51:15 AM
Hey, brother!

Any updates on the treatment?