I'm about 3 months into Peyronies Disease and my doctor put me on Cialis and is recommending Xiaflex as my curve is about 45 degrees. I am concerned because it seems early and I worry about the possible side effects. I've been using the Restorex device but have not had much improvement (if any).
My wife and I started trying to get pregnant around the onset of this awful disease. My biggest fear is Xiaflex side effects will prevent us from having kids.
I've never heard of xiaflex making someone impotent.
I am now on my forth cycle of Xiaflex ( eight injections ) without any major side effect other than swelling and bruises that sometimes spreads to my scrotum. The hourglass and curvature has significantly fading away. I did see the pictures showing significant side effects but my Doctor told me to not worry about that and just follow his advice by the syllable, what i did it. I am 68 yo and I still have strong erections and I always experienced night erections,( I usually wake up four time during the night with erections that most of the time does not go down easily) what has been a great concern since the begin of my treatment taking in consideration that a strong erection may cause rapture of the corpora yet fortunately that hasn't happened with me so far. As far as I know, pumps devices can be very dangerous during the treatment with Xiaflex injection and I would not recommend it to anybody. Despite of been out of any major side effect up to the present moment I have to confess that I am always scarred to get next injection done.
Good luck for you.