My oral treatment

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alec

I have notived the indentation and curvation 1 month ago. Uro confirmed a plaque on ultrasound. Now i am taking pentox (400mg x 3 daily), cialis (5mg x 1 daily), l'arginin (daily), l'carnitin (daily), Vitamin-E (400mg x 1 daily), vitamin-d (5000IE x 1 daily), acetylcysteine (600mg x 1 daily) and i am thinking what else could help or be worth try? Any advice on oral medication?
I will also do ved and start traction soon.  
30yrs, diagnosed in feb. 2018 after possible injury (not sure), 4 plaques, 4 dents, S-surve, 30° right/45° up curve, tingle in the legs, sometimes penile pain an depressed.

betterbend

Change l arginine to l citrulline, 1500 mg daily.  IT converts 100% to arginine in the body.  L'arginine taken orally gets metabolized in the liver and it's only 30% available. Avoid the malate powder, it is bad for the teeth,unless it's in capsule form.  You could add coq10 400 mg daily, it's expensive,but a good antioxidant.

Consider traction with one of the many devices discussed on this site.  
55 - Onset May 2017.  38 degree bend up.  Failed Xiaflex treatment.  Still functional so I decided to stop treatments.  Only take 400mg Co-Q10 and occasionally use Restorex

TonySa

Consider adding VED and/or traction.
PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

thinkpositive

After a week of research, here are my current notes on a 3 optional ways forward...hopefully the senior members of the board chime in, they are all a big help

Option 1:
Seems like the standard protocol a great majority of forum members agree with
Medicine:
400 mg of Pentoxifylline/Trental, 3x daily (breakfast, lunch, dinner)
Cialis 5mg 1xday

Supplements:
Natural 200mg Vit E 2x daily (breakfast, dinner)
Multi-Vitamin 1xday

Supplement Variables:
L-Citrulline 1500 mg daily (L-Citrulline powder from Doctor's Best brand)(replaces L-Arg)
Ubiquinol 100MG 2xday (replaces C0Q10)
Acetyl L-Carnitine 1.5 - 3 grams per day divided into 2 or 3 dose

Topical:
Castor Oil 2x Daily
Diclofenac sodium 1% gel twice daily (trying to get 4%)


Option 2:
This option is insprired by Doctor Gianni https://www.hindawi.com/journals/au/2017/4653512/#B90

Medicine:
400 mg of Pentoxifylline/Trental, 3x daily (breakfast, lunch, dinner)
Cialis 5mg 1xday

Supplements:
Natural 200mg Vit E 3x daily (breakfast, lunch, dinner)
Multi-Vitamin 1xday

Supplement Variables:
Propolis 200MG 3xday (on an empty stomach)
Blueberry 160MG 1xday (Vaccinium myrtillus L)

Topical:
Castor Oil 2x Daily
Diclofenac sodium 1% gel twice daily (trying to get 4%)

Optionally: Trying to find a doctor who can give me Pentoxifylline 100 mg perilesional injections (twice a month for 6 months, total = 12)


Option 3:
Hope the supplements will play well together?
Medicine:
400 mg of Pentoxifylline/Trental, 3x daily (breakfast, lunch, dinner)
Cialis 5mg 1xday

Supplements:
Natural 200mg Vit E 3x daily (breakfast, lunch, dinner)
Multi-Vitamin 1xday

Supplement Variables:
L-Citrulline 1500 mg daily (L-Citrulline powder from Doctor's Best brand)(replaces L-Arg)
Ubiquinol 100MG 2xday (replaces C0Q10)
Acetyl L-Carnitine 1.5 - 3 grams per day divided into 2 or 3 dose
Propolis 200MG 3xday (on an empty stomach)
Blueberry 160MG 1xday (Vaccinium myrtillus L)

Topical:
Castor Oil 2x Daily
Diclofenac sodium 1% gel twice daily (trying to get 4%)



Paolo

I like option 3, however when you run out of ALC consider a combination with ALA, Alpha Lipoic Acid for possible mitochondrial dysfunction, if cost is not a consideration even better is RLA, a reduced form of ALA and thought to be more bioavailable  :)

I try to take ALA in 'small' doses, 100mg per tablet as (my theory) is that your body can only use tiny amounts, so for me 6 pills per day. Above all else it is a fantastic skin supplement, that of course would include you penis LOL.

Nice protocol  :) I think you have also stated an exercise routine, that's good.

EDIT 22/04/18............. Guys use R-LA instead of ALA, I am surprised at the 'marked' difference in energy switching to this form of Lipoic Acid.
Whenever you find yourself on the side of the majority, it is time to pause and reflect.

thinkpositive

Yes, thats right.. I was trying to keep my post just about Oral Treatments.  Here are my current notes as of this afternoon (still a work in progress):

6 -12 Month Therapy
Currently have no plaque in ultrasound and 25 degree bend left toward the base

Option 1:
Seems like the standard protocol a great majority of forum members agree with
Medicine:
400 mg of Pentoxifylline/Trental, 3x daily (breakfast, lunch, dinner)
Cialis 5mg 1xday

Supplements:
Natural 200mg Vit E 2x daily (breakfast, dinner)
Multi-Vitamin 1xday (with lunch)

Supplement Variables:
L-Citrulline 1500 mg daily (L-Citrulline powder from Doctor's Best brand)(replaces L-Arg)
Ubiquinol 100MG 2xday (replaces C0Q10)
Acetyl L-Carnitine 1.5 - 3 grams per day divided into 2 or 3 dose

Propolis 200MG 1xday (on an empty stomach in-between meals)
Blueberry 80MG 1xday (Vaccinium myrtillus L)

Topical:
Castor Oil 2x Daily
Diclofenac sodium 1% gel twice daily (trying to get 4%)

VED:
Light Use

Traction:
RestoreX

Blood Tests:
Every 4 weeks

Ultrasounds:
Every 6 months

Option 2:
This option is insprired by Doctor Gianni https://www.hindawi.com/journals/au/2017/4653512/#B90

Medicine:
400 mg of Pentoxifylline/Trental, 3x daily (breakfast, lunch, dinner)
Cialis 5mg 1xday

Supplements:
Natural 200mg Vit E 3x daily (breakfast, lunch, dinner)
Multi-Vitamin 1xday (with lunch)

Supplement Variables:
Propolis 200MG 3xday (on an empty stomach in-between meals)
Blueberry 160MG 1xday (Vaccinium myrtillus L)

Topical:
Castor Oil 2x Daily
Diclofenac sodium 1% gel twice daily (trying to get 4%)

Optionally: Trying to find a doctor who can give me Pentoxifylline 100 mg perilesional injections (twice a month for 6 months, total = 12) - if I can get these injections, I will lower the Pentox daily to 2xdaily as per Doctor Gianni's study

VED:
Light Use

Traction:
RestoreX

Blood Tests:
Every 4 weeks

Ultrasounds:
Every 6 months

Option 3 (Paolo's fav):
Hope the supplements will play well together?
Medicine:
400 mg of Pentoxifylline/Trental, 3x daily (breakfast, lunch, dinner)
Cialis 5mg 1xday

Supplements:
Natural 200mg Vit E 2x daily (breakfast, lunch, dinner)
Multi-Vitamin 1xday (with lunch)

Supplement Variables:
L-Citrulline 1500 mg daily (L-Citrulline powder from Doctor's Best brand)(replaces L-Arg)
Ubiquinol 100MG 2xday (replaces C0Q10)
Acetyl L-Carnitine 1.5 - 3 grams per day divided into 2 or 3 dose
Propolis 200MG 3xday (on an empty stomach in-between meals)
Blueberry 160MG 1xday (Vaccinium myrtillus L)

Topical:
Castor Oil 2x Daily
Diclofenac sodium 1% gel twice daily (trying to get 4%)

VED:
Light Use

Traction:
RestoreX

Blood Tests:
Every 4 weeks

Ultrasounds:
Every 6 months


betterbend

The ultrasound is not a pleasant experience, as they will induce an erection via injections, because it is a doctors office getting an erection isnt the easiest thing, its not like being in bed with your girl (or guy), its very clinical.  It took a total of three injections to work.  It got so hard it was uncomfortable.  They then have to inject psuedophedrine to stop the erection, because you should not leave the office with an induced erection. I felt like like I was beaten up after that experience.   I would say ultrasound every 2 months is overkill.  I would get a baseline, start your treatments and absent any changes for the worse, get another ultrasound at six months to see where you are at.  Having a baseline and six month measurement by the same person will give you a good idea if you are stable, or progressing.
55 - Onset May 2017.  38 degree bend up.  Failed Xiaflex treatment.  Still functional so I decided to stop treatments.  Only take 400mg Co-Q10 and occasionally use Restorex

Vlad

Hello

Topical:
Castor Oil 2x Daily
Diclofenac sodium 1% gel twice daily (trying to get 4%)

Question: how to use one and the other 2 times a day?

Sorry for my English
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