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Author Topic: Is trimix gel safe?  (Read 4282 times)

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Josh203

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Is trimix gel safe?
« on: February 23, 2018, 04:39:08 AM »

So I have an order of trimix gel to help with erections and blood flow but I am scared to use it. I have read trimix injections have caused peyronies in some people in this forum. Also whats the best way to have an erection for any imaging without hurting my penis anymore?
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Paolo

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Re: Is trimix gel safe?
« Reply #1 on: February 23, 2018, 05:13:59 AM »

Hi Josh, you should carefully read member Christopher1 posts, he is in medicine (I think), he swears Trimix set off his peyronie's episode  :(
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TonySa

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Re: Is trimix gel safe?
« Reply #2 on: February 24, 2018, 04:45:11 PM »

I believe it set mine off as well. At least one study showed 4% had this side effect.  However, Dr Lue, a well renown peyronies specialist told me this can be avoided by putting pressure immediately at the site of injection for at least 5 minutes. Hebsays this stops the bleeding which is crucial as if you don’t and bring in more blood for the erection it causes the trauma triggering peyronies.
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

TonySa

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Re: Is trimix gel safe?
« Reply #3 on: February 24, 2018, 04:45:43 PM »

Where did you find trimix gel?
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

Christopher1

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Re: Is trimix gel safe?
« Reply #4 on: April 09, 2018, 05:05:49 PM »

Correct. I would avoid injecting unless absolutely necessary (e.g. spinal cord injury or severe Erectile Dysfunction).
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Snake Diet + 5-day fasts + NeoV's stretching routine. Curvature 99% gone. Still have bothersome scar pain. Please message me for a good Peyronies Disease pain cure.

I also recommend an auto CPAP device --> increases REM sleep --> increased nocturnal erection.

TonySa

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Re: Is trimix gel safe?
« Reply #5 on: April 09, 2018, 05:55:22 PM »

Spinal cord injury for penis injection?
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

Christopher1

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Re: Is trimix gel safe?
« Reply #6 on: April 15, 2018, 09:22:24 PM »

Yes, Tsanchez12369 - spinal cord injury can lead to some very unfortunate conditions, such as paralysis or permanent Erectile Dysfunction.

People with a spinal cord injury can use Trimix with nice results. Hopefully, of course, they are not one of the few unlucky people who develop Peyronies Disease from it.
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Snake Diet + 5-day fasts + NeoV's stretching routine. Curvature 99% gone. Still have bothersome scar pain. Please message me for a good Peyronies Disease pain cure.

I also recommend an auto CPAP device --> increases REM sleep --> increased nocturnal erection.

TonySa

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Re: Is trimix gel safe?
« Reply #7 on: April 16, 2018, 09:53:25 AM »

I see, I hought you met injection in penis resulted in spinal cord injury...
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

james1947

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Re: Is trimix gel safe?
« Reply #8 on: April 23, 2018, 07:29:30 AM »

I don't think:
Quote
.....few unlucky people who develop Peyronies Disease from it
I think many, especially if for long period.

By the way Josh, I am asking the same question as Tsanchez:
Quote
Where did you find trimix gel?
Also how it penetrates the penis skin?

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

TonySa

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Re: Is trimix gel safe?
« Reply #9 on: April 23, 2018, 10:23:40 AM »

I think my peyronies was from the trimix injections.  However, Dr Lue says that can be avoided if pressure is put to the injection site for 5-7 minutes afterward rather than just until it quits bleeding externally.  It’s apparently important to ensure any internal bleeding has stopped before the engirgement of the induced erection.
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

james1947

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Re: Is trimix gel safe?
« Reply #10 on: April 28, 2018, 03:50:12 AM »

Josh

Can we get some answers?
We are really interested

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

Christopher1

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Re: Is trimix gel safe?
« Reply #11 on: May 06, 2018, 07:44:14 PM »

I don't know what the incidence of Peyronies Disease from Trimix is.

I have actually taken care of people with spinal cord injuries who use it frequently without problems. Overall though - I wouldn't recommend it unless absolutely necessary. It is just too risky.
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Snake Diet + 5-day fasts + NeoV's stretching routine. Curvature 99% gone. Still have bothersome scar pain. Please message me for a good Peyronies Disease pain cure.

I also recommend an auto CPAP device --> increases REM sleep --> increased nocturnal erection.

Josh203

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Re: Is trimix gel safe?
« Reply #12 on: May 18, 2018, 03:02:49 PM »

I just looked back at this post and see some of you are interested about the trimix gel. I got it from my urologist, its not an injection it goes down the urthera instead. It is like the gel Muse but with trimix you dont have to insert the applicator down your urthera.
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Christopher1

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Re: Is trimix gel safe?
« Reply #13 on: May 18, 2018, 03:35:34 PM »

Just be careful.
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Snake Diet + 5-day fasts + NeoV's stretching routine. Curvature 99% gone. Still have bothersome scar pain. Please message me for a good Peyronies Disease pain cure.

I also recommend an auto CPAP device --> increases REM sleep --> increased nocturnal erection.

TonySa

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Re: Is trimix gel safe?
« Reply #14 on: May 19, 2018, 12:42:37 AM »

I heard the incidence is 4%, maybe more but def not a large percentage.  My doc says chances pretty much non-existence if hold pressure on injection site for 7+minutes to stop any internal bleeding which creates the trauma resulting in peyronies.
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

rwilson

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Re: Is trimix gel safe?
« Reply #15 on: May 22, 2018, 06:58:03 AM »

I have never heard about this medication before for erection. What i know and have used is Viagra which is very effective and works really well without giving any side-effects. I am facing erection problem since last two years and its quite embarrassing for me because m just 26 and i have to face this problem so early.Anyways without consulting any doctor i have started taking Viagra and am not facing any problem.
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TonySa

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Re: Is trimix gel safe?
« Reply #16 on: May 22, 2018, 07:21:36 AM »

Can you share the prescription for trimix gel, is it compounding Rx?
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

Christopher1

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Re: Is trimix gel safe?
« Reply #17 on: May 26, 2018, 12:02:14 PM »

I think I read papaverine is inherently fibrotic.

I am just not a fan of these injections or chemicals. My urologist also never warned me at the time that this was a possibility. I still carry a lot of resentment towards that urologist for not warning me.
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Snake Diet + 5-day fasts + NeoV's stretching routine. Curvature 99% gone. Still have bothersome scar pain. Please message me for a good Peyronies Disease pain cure.

I also recommend an auto CPAP device --> increases REM sleep --> increased nocturnal erection.

Raven2

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Re: Is trimix gel safe?
« Reply #18 on: October 27, 2018, 11:17:58 AM »

My dr also didn’t warn me about holding the penis for 7 minites and I got Peyronies from the injection. I’m 100 percent sure as it started at the injection site and kept growing for a year. I used injections for a bout two years. Worked great. Also now my blood flow is really good. Side effect from the injections. Which is great. But a bent penis sucks.
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suicidecomingsoon

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Re: Is trimix gel safe?
« Reply #19 on: October 27, 2018, 11:19:42 AM »

[Full quote remove - use 'REPLY' instead of 'QUOTE'] - ADMIN

Was it alpostradil or bimix, trimix?
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Hawk

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Re: Is trimix gel safe?
« Reply #20 on: October 27, 2018, 11:49:49 AM »

This topic is about gel, not injections so I will likely split it and maybe even merge it with another topic on injections.

1. Papaverine is available at a low cost and is stable at room temperature but is less effective than the other medications and may have a higher tendency to cause scarring (fibrosis).

2. Papaverine plus phentolamine (BiMix) is more potent than papaverine alone but with the same potential side effects such as priapism and scar tissue formation.

3. Alprostadil rarely causes priapism but with its use pain is more common.  (Alprostadil is also known as prostaglandin E-1 or PGE-1, in powdered form it may be called Caverject or Edex.)

4. Papaverine plus phentolamine plus Alprostadil (Trimix) is the most potent but requires refrigeration and has the same side effects as Papaverine and Alprostadil.
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Christopher1

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Re: Is trimix gel safe?
« Reply #21 on: November 02, 2018, 02:51:57 PM »

Raven - you mentioned your blood flow is good after Trimix.

Are you basically stating that the Trimix injections improved your natural ability to have erections? I have heard of this phenomenon but only from 2 patients and 1 urologist. I am not sure how true it is.
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Snake Diet + 5-day fasts + NeoV's stretching routine. Curvature 99% gone. Still have bothersome scar pain. Please message me for a good Peyronies Disease pain cure.

I also recommend an auto CPAP device --> increases REM sleep --> increased nocturnal erection.

Bud luck

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Re: Is trimix gel safe?
« Reply #22 on: August 16, 2020, 01:03:14 AM »

I got my Peroynes 8 months ago after the "Doctor" injected me a Trimix injection that left me with a excruciating painful erection for over 3 hours. After 8 months I still don't have a palpable plaque, my penis has a dent in the same area of the injection, also at the same area I have narrowing and "hinge effect" when is semi hard, but not when is hard. Maybe if I just inject Alprostadil on the other areas of the penis far from the dent? Any of you are still injecting trimix or alprostadil having Peroynes?
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Bud luck

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Re: Is trimix gel safe?
« Reply #23 on: August 16, 2020, 01:05:27 AM »

Also, why not use Trimix gel?. The company that makes Trimix gel advice guys with Peroynes not to use it, why not?
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Hawk

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Re: Is trimix gel safe?
« Reply #24 on: August 16, 2020, 01:06:35 PM »

There is data that suggest that some of the components of BiMix and TriMix can cause fibrosis.  This is not just from any micro trauma of the needle but the drug itself.  I cannot say that it cannot happen form 1 injection but is much more likely if injecting multiple times weekly over a period of time.
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Hawk - Updated 10/27/18 - Peyronies Society Forums

TonySa

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Re: Is trimix gel safe?
« Reply #25 on: August 16, 2020, 02:55:32 PM »

Hawk is one mixture more or less prone to fibrosis?  Surgeons will move ahead w an implant if someone doesn’t want to risk the injections.
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

Hawk

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Re: Is trimix gel safe?
« Reply #26 on: August 16, 2020, 11:11:04 PM »

There is some controversy but usually  Papaverine is considered more likely to cause fibrosis.  It is found in BiMix and TriMix but at lower levels in TriMix
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After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

AnonDoc

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Re: Is trimix gel safe?
« Reply #27 on: October 28, 2020, 08:24:10 AM »

I think most of the Peyronies from these drugs is caused by trauma from injection and blood going where it shouldn’t be.

Micro trauma to blood vessels with some bleeding could occur from an unusually/painfully hard erection.

Also long term there seems to be anecdotal girth increase on Trimix.
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