Treatments to encourage nocturnal erections

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newguy

For men with or without peyronie's it appears to be the case that nocturnal erections are a sign of healthy sexual functioning. Where they are not present or are not frequent that is of course a concern. I've seen it mentioned here that Trazodone (Desyrel, Beneficat, Deprax, Desirel, Molipaxin, Thombran, Trazorel, Trialodine, Trittico) at doses of around 25mg can prove to be very helpful for night time erections, but I've had mixed experiences with it myself. The first time I took it I woke up with an erection that remained for around 20 minutes (which, in a sense in quite worrying, but at least not in priopism territory). Following on from that though, it has not resulted in regular morning erections, they do occur but by no means on a regular basis. This is making me wonder if I have built up some kind of immunity to it (that seems unlikely), or maybe it isn't as effective at times due to pre-sleeping habits (sometimes taking it with food, sometimes not). Another consideration is that 'maybe' it takes a few weeks to reach optimal effectiveness.

My day time erections are if anything, stronger than a few months ago (possibly due to the l-arginine + pycnogenol combo - http://www.ncbi.nlm.nih.gov/pubmed/12851125?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum), so I'm wondering if there are any other alternative to trazodone when it comes to promoting night time erections?

Hawk

I introduced Trazodone here and have used it regularly for 2years and off and on for several years.  After 2 years of regular use, I did go through a period where I wondered if the NTE effect was diminishing.  For that and several other reasons I discontinue Trazodone for a couple month.  I now use it periodically and it works as good as ever.

However, just 2 days ago I started back on 2 Arginine capsules (Vasoflow),  60 mg pycnogenol, and a couple horny goat weed capsules about an hour before bed.  Though it has been only two nights the effect seems almost as good as Trazodone.  I think the pycnogenol made that combo really work for me. Time will tell.


PS:New Guy, I am inclined to move this to the ED Board
Prostatectomy 2004, radiation 2009, currently 70 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

George999

I think this observed synergy between Pycnogenol and L-Arginine is really an important observation and really potentially very useful to a number of guys with ED issues.  Thus I think it really does belong on the ED board since lack of nocturnal erections is a classic symptom of physiologically driven ED.  Just my 2c.  - George

newguy

 
QuoteHowever, just 2 days ago I started back on 2 Arginine capsules (Vasoflow),  60 mg pycnogenol, and a couple horny goat weed capsules about an hour before bed.

I tend to take arginine with pycnogenol in the morning, but just arginine at night. I'll alter my routine to see if it makes a difference. It definitely does the trick during the day.


(I think the topic can potentially fit into either baord, but upon reflection I do see more reasons than not for why it should be located here (the ED Board).)

Wintercookie

I take 20 mg cialis and 1000mg of vasoflow as a matter of routine but it doesn't generally induce morning erections and when it does they are sub optimal for penetration.    Oh for my innocent youth.

newguy

Quote from: Wintercookie on September 22, 2009, 05:51:53 AM
I take 20 mg cialis and 1000mg of vasoflow as a matter of routine but it doesn't generally induce morning erections and when it does they are sub optimal for penetration.    Oh for my innocent youth.

Certainly ED causes more trouble for some than others. Have you tried adding anything else to your routine. Maybe Tongkat Ali? Have you had your T-Levels checked?

Hawk

Quote from: Wintercookie on September 22, 2009, 05:51:53 AM
I take 20 mg cialis and 1000mg of vasoflow as a matter of routine but it doesn't generally induce morning erections and when it does they are sub optimal for penetration.    Oh for my innocent youth.

I would also consider some pycnogenol 60mg

1/2 of a 50mg prescription trazadone also gives good results with nocturnal erections and costs only a couple cents per dose.
Prostatectomy 2004, radiation 2009, currently 70 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums


despise

I'm currently trying to figure out what would be the best way to achieve nocturnal erections. Are you supposed to take l-arginine with the pyconogel? Should you take trazadone with them?  

skunkworks

Just a note from my side of hte fence, trazodone did not help my erections at all.

My number one recommendation for nocturnal and morning wood is low dose naltrexone. The stuff is dynamite.
This is an emotionally destructive condition, we all have it, let's be nice to each other.

Review of current treatment options by Levine and Sherer]

Lennyman

B-complex, dhea 25 mg, melatonin, 5-htp works for me
Lenny was here  :)

angelinadiaz

 Generic medicine like kamagra,zenegra,generic levitra are useful for ED.

mech1

hi all
what dose l arginine and pyconogel do you take to achieve good erections

inkhorn

Mech1- Back when I could get an erection I took 5000mg of arginine 1 hr before sex. Worked as good as any ED med. Have not taken the pine bark in many years, but I think I will again. As far as horny goat weed, yohimbe etc, that worked but always made me feel weird. Inkhorn  

mech1

thanks mate im weary of Viagra after what the doctor told me about making my peyronies worse .

jackp

My doctor started me on Viagra the week after it was available. Since then I have been on all the ED drugs. None of which helped me. I have seen nothing that to verify that the ED pills will give you peyronies.

There are ED drugs that will give you peyronies. Injections into the corpus caversonum for erections. Those are, but not limited to, PGE1 and tri-mix. None of those helped me either all they did was make my condition worse by causing corporal fibrosis.  

The majority of men that start injections for ED stop within a year. My advice to anyone considering it is DON'T! If you do be aware of peyronies or the development of corporal fibrosis. If you have ED that does not respond to the drugs use a VED with constriction rings for sex.

Been There Done That!

Jackp
http://jackp-penileimplant.blogspot.com

james1947

mech1

The only damage Viagra can make you is if you have a hard erection with it and you will bend your penis by accident you may develop Peyronies.
It helped me for a while, now the effect is very limited.

James
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe ED.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

mech1

thanks lads
im gonna try the 5000 grams of l- arginine to see if that works as advised on here if not I will give the Viagra a go my problem is I get erect ok but if I stop midway through for one reason or another I lose it quickly never used to happen could stay hard for ages I find it depressing as when having sex I feel like im rushing in case I lose my erection its horrible and the doctors here don't really seem to care  

inkhorn

Mech- Definitely try the the cock ring with or without the help of the VED. You'll stay as hard as you want as long as you want.Regards Inkhorn

koolx

lets say u take pycnogenol and l-arginine for a while and it improves erections. now say after this improvement that u take cialis. will this create even more improvement? has anyone tried this?

Hawk

Below is a quote from a link posted by Obsie

QuotePDE-5 inhibitors and nitrates: Patients using a PDE-5 inhibitor should never take a nitrate. The duration of action of a PDE-5 inhibitor (hours versus days) is irrelevant, if intercourse activity may produce angina that may require nitroglycerin in any form (pill, patch,  spray, or sublingual). Studies have shown that in 8% of men, the combination of a nitrate and a PDE-5 inhibitor can cause a precipitous drop in blood pressure, as much as 40 mm Hg, which could cause sudden cardiac death or other signs of vascular insufficiency. The problem is that we cannot predict which men will be in the 8% that experience this effect, so the contraindication is firm and the same for all of the PDE-5 inhibitors.

The issue is that while l-arginine is not a nitrate, it does increase nitrate levels in the body.  I have taken this combination but proceed with caution.
Prostatectomy 2004, radiation 2009, currently 70 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

GS

I started taking my L- Arginine in the morning and my PDE-5 inhibitor before I go to bed.  At least that way you are spreading them out.  So far, I still wake up with an erection every morning.

GS

Chimp2020

Hi.  I know this is old post but couldn't see a newer one that specifically talked oral men's and nocturnal,erections

Background mid 40's with life time of ED issues that I've only just truly acknowledged, never had spontaneous erection or nocturnal erections that I can ever remember. Pyronies too although relatively mild. Started using VED unit 6 days ago after recommendation from urologist.

Hawks suggestion of trying 25mg Trazadone has been a revelation, last 2 nights and morning has been amazing. So this is what's supposed to happen. The effect on resting state size lasts most of day too.

Q - Is it safe to take viagra at same time as Trazodone?
Q2 - pycnogenol and L arginine doses to achieve similar effect to trazadone? Trazadone makes me a little groggy in morning so wondered if this might be a better combination.

Thanks for any help in advance. (And thank you Hawk!)
Age 47
Had ED all my life, tried all the meds
Dupuytren's with mild peyronies

McChicken94

Nighttime cialis/viagra often increases my odds of waking up with a boner.
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Chimp2020

Hi there, thanks for reply. My doctor said there were no issues with taking both as operated on different metabolic pathways.
I was just seeing if anyone had tried this as now I have NTE but still need to take something else to get it going for sexual arousal purposes

Age 47
Had ED all my life, tried all the meds
Dupuytren's with mild peyronies

jan.schaller1958

If you're doc has okayed it, fine. Just wanted to be sure you checked first.  
THIS USER HAS BEEN BANNED FROM FORUM FOR RULE VIOLATIONS

postrocker

Hi everyone

For how long can you take PDE-5 inhibitors safely? Months? Years? Decades? Anyone?

Their effects decrease with time?

After starting you can only have sex and have an erection if you have one?

Thanks
37yo
Congenital curvature plus injury during sex - dec.2019
Curve to the left increase plus pain ~35degrees - nov.2020
Pentox (400mgx3) + Cialis (2.5mg/day) + supplements - dec.2020
Traction - jan.2021 onwards (curve now ~22/25degrees)

NeoV

Vitamin D at night restored my erections and for many men I've spoken to. If you're already taking it, then probably consider your diet and other supplements or cialis, as well as sexual habits.

FlavioSousa

I tried trazodone a few years ago and side effects were unbearable: headaches, insomnia, restlessness.

The combination L-arginine + pycnogenol was, however, very effective. There's a supplement called PRELOX that combines both ingredients. I took it for some time but I believe L-arginine worsened my hair loss, so I stopped.
Psychogenic ED (coital anxiety), 40+yo. Current regimen: udenafil 200mg, oral phentolamine mesylate 40 mg, Seredyn.

Chimp2020

Just thought I'd do an update. Taking 25mg trazadone started to lessen NTE after 4 days and only seems to make an effect if I stop taking it for a few days and then start again.

I since read around this forum and ordered up some L- Arginie,  L- Citrulline and pycnogenol . I didn't expect it to work at all as just 'food supplements and pine wood extract. It's been over a week now and the results are nearly as good as trazadone for NTE and a noticeable size difference when at rest. It for once finally feels like its got some life in it when at rest.

Sadly when I need it to work it's still a battle and only really 'works' when I take sildenafil but that now I can take less to get the same effect. I get lower back ache with either cialis and sildenafil.

Q - Any other pde 5 that are less prone to this - is Levitra any good?

I'm taking (a day)
2000mg L- Arginine
1500mg L-Citrulline
130mg pycnogenol
25ug of Vit D

Q2- how long did VitD supplements take to make a difference?

Q3 - Anyone take Horny Goat Weed - Yohimbine with all that lot?

I'm going to start rattling with all this lot but I am astounded how much difference the amino acids and pycnogenol have made. I feel for once in a long long time there might be some light at end of the tunnel. I just need it to operate when I want it to.....
Age 47
Had ED all my life, tried all the meds
Dupuytren's with mild peyronies

NeoV

Vitamin D worked immediately for me, but probably could take a while until your vitamin D levels are restored.

Vitamin D plus consuming saturated fat and avoiding grains is what helps mine the most, as well as absolutely no porn whatsoever (which takes a month or two to see the benefits).

Bud luck

I read on the trazodone oficial site, that is contraindicated for penis bent or Peroynes, anyone knows why?
My first symptoms started early in 2019
I tried Traction device, Pentofixiline, Q10, TRT, L-Argenine, cialis
I have narrowing/dent/hinge on the left side of my shaft
My ED is getting worse
Had a PRP shot Aug 2021
I have a girlfriend
Age 46

TonySa

PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

FlavioSousa

Quote from: inkhorn on August 22, 2013, 06:31:15 AM
Mech1- Back when I could get an erection I took 5000mg of arginine 1 hr before sex. Worked as good as any Erectile Dysfunction med. ...

This is very interesting.

Are you saying that 5000 mg arginine as needed is as effective as Cialis or Viagra? Do you think arginine increases testosterone levels and could this worsen male pattern baldness? There are studies that claim this and I believe it was worsening my hair loss, so I stopped.
Psychogenic ED (coital anxiety), 40+yo. Current regimen: udenafil 200mg, oral phentolamine mesylate 40 mg, Seredyn.

Chimp2020

Hi.

Can anyone offer advice as morale is rather low at the moment. Almost a day after posting about the progress I had made with Arginine, Citrulline and pycnogenol I woke up to find I was back at square one.

1) Trazadone 25mg worked for 2 days in a row, if I stop taking it for a 3 days then start again seems to have similar effect but for a few days then nothing. I do feel quite groggy in the morning with even this low dosage. So I moved onto:

2) Arginine, citrulline & Pycnogenol worked great for NTE and general blood flow when at rest for exactly 13 days and now nothing for the last 3 days. I've not changed anything else.

I'm pretty upset after making what I thought was a breakthrough for 13 days.

Q - Has anyone else experience this tolerance/adaptation of arginine/pycnogenol combo?

Q2 - How much more arginine/citrulline can I take?

Any constructive advice would be welcome. Thanks.

Age 47
Had ED all my life, tried all the meds
Dupuytren's with mild peyronies

Hawk

I used Trazadone for many years and seemed at times to adapt to it so I would rotate off of it for a while. You can easily take 3,000 mg of L-Argine/L-Citrulline.  Body builders often take much more.  It can cause stomach upset on an empty stomach and sometimes a herpes simplex (cancer sores in the mouth although I never experienced that at any does.  Again, I would not use it every day but more like 3 - 4 days a week.
Prostatectomy 2004, radiation 2009, currently 70 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

FlavioSousa

Quote from: Chimp2020 on November 29, 2020, 04:52:03 AM
[...] I get lower back ache with either cialis and sildenafil. [...]

I am going to try udenafil soon and its makers claim that this drug is more selective than other PDE-5 inhibiters and does not cause back pain. BUT I haven't tried it yet, so I can't say for sure.

If you want to try udenafil, I strongly recommend you get the original brand drug from Dong-A and not some crappy generic. Send me a PM, if you want more details.


Therefore, udenafil has a relatively rapid onset of action (like sildenafil and vardenafil) and a long duration (but not as long as tadalafil). Furthermore, it does not inhibit PDE11 like tadalafil and it is not associated with visual disturbances or myalgia (like sildenafil–vardenafil and tadalafil, respectively).

https://www.europeanurology.com/article/S0302-2838(08)00851-8/fulltext


I don't understand the part about pycnogenol, it's just an antioxidant meant to keep good blood circulation. I take an excellent pycnogenol complex (no L-arginine, I don't want to risk my hair) from Naturmil before going to sleep and it's been great. My erections are harder and more frequent.
Psychogenic ED (coital anxiety), 40+yo. Current regimen: udenafil 200mg, oral phentolamine mesylate 40 mg, Seredyn.

Chimp2020

Hi

I'd got a great result from 2.5mg cialis (evening) and 2.5mg (morning). If I took 50mg Sildenafil on evening I wanted the 'tackle' to actually work then I'd skip the evening 2.5mg cialis.

However I just can't get away from the fact that either 2.5mg or 5mg /day cialis will give me chronic lower back ache and I just cant tolerate it.

Has anyone taken trazadone some evening then viagra the next - or both together. I had one Dr say they didn't have same MOA so it was fine but wondered if anyone on here had experience of that?

Thanks
Age 47
Had ED all my life, tried all the meds
Dupuytren's with mild peyronies

Hawk

I have taken Trazadone with Viagra and Levitra plus threw in some L-Arginine.
Prostatectomy 2004, radiation 2009, currently 70 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

Juan

Hi Chimp, I recently asked in the forum about doing this and someone told me not to do it as tadalafil has a long life in the organism etc.
Do you do this by your own decision or did you ask doctor? Thanks
Quote from: Chimp2020 on January 25, 2021, 09:16:53 AM
I'd got a great result from 2.5mg cialis (evening) and 2.5mg (morning).

I take 2,5 tadalafil before bed and have nte every night (also take 100mg of pycogenol at dinner. I think this also contributes)

My question about nte: how are supposed to be? One or two long lasting (hours) erections or multiple short erections?

39 yo. Onset Oct/20. 25º dorsal bend 1cm before glans + high erection angle.
Pentoxifiline 400x3. Tadalafil 2,5. Vit E, D3, K2. Zinc.Omega3. Ubiquinol. ALCAR.
Traction with PMP.

Chimp2020

Hi Juan

If I remember tadafil has a half life of 16 hours. You can take the max dose of 5mg a day (if taking daily). I split it up to try and get past back pain.

The best results I've ever had was 2.5mg morning and 50mg Viagra evening for actuall action. That way very little /no flushing of face or blurred vision. If I didn't need it for action then 2.5 mg each morning and evening seemed to keep night time erections. How NTE should be? Your asking the wrong guy as I've never really had them until I started taking these meds. I've no idea what normal is

I'm back on 100mg V as back pain with cialis. It's no where near as good and I'm flushed in face etc.

Good luck Juan.

Age 47
Had ED all my life, tried all the meds
Dupuytren's with mild peyronies

Hawk

It does not matter if your erections last one or two hours, as long as they do not stay constant for over 4 hours.

In theory, it might get more oxygen to the penis if you had eight, 15-minute erections, but no one can control that.  Also, if they are sleep erections, you can never even monitor that to know, so there is no point in worrying about it.
Prostatectomy 2004, radiation 2009, currently 70 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums