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Welcome to Dr. Landon Trost - Directly answering member questions in the "Medical Professionals" section below the Treatment boards. https://www.peyroniesforum.net/index.php/topic,16512.0.html

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Author Topic: CD47 antibody phase-1 clinical trial  (Read 2975 times)

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Crooked_Stick

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CD47 antibody phase-1 clinical trial
« on: April 19, 2017, 10:12:40 AM »

Very interesting read......may have implications for us!

https://medicalxpress.com/news/2017-04-fibrosis-reversed-dont-blocked-stanford.html

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Born 1960, Diagnosed 2013
Initial 40 degree bend, 1" loss, Xiaflex 3 rds of 2 injections
Current 25 degree bend, no palpable plaque, 1/4" loss
VED 5-6 days/week, traction daily,
TRT 20 ml twice weekly, Cialas 3 mg - No Erectile Dysfunction - Doing Well!

james1947

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Re: CD47 antibody phase-1 clinical trial
« Reply #1 on: April 19, 2017, 03:49:16 PM »

Maybe a breakthrough regarding dissolving our plaques also?
Hope it will be in my life time  :)

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

Sta

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Re: CD47 antibody phase-1 clinical trial
« Reply #2 on: April 20, 2017, 09:12:31 AM »



Could not agree more
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Born 1985, Peyronie's since 2011/12. Lost approximately 3 cm of length and seriously bottlenecked.

Crooked_Stick

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Re: CD47 antibody phase-1 clinical trial
« Reply #3 on: April 20, 2017, 10:19:07 AM »

I read that in one of the ongoing cancer trials using this they are asking patients if they have any fibrotic condition and then testing after treatment to se if there is improvement. The CD47 protein covers both fibroblasts and canncer cells in the same way and 'masks' them from your immune system so that they are protected. The CD47 anti-body un-masks the cells so your body can eradicate them.....cool!
Logged
Born 1960, Diagnosed 2013
Initial 40 degree bend, 1" loss, Xiaflex 3 rds of 2 injections
Current 25 degree bend, no palpable plaque, 1/4" loss
VED 5-6 days/week, traction daily,
TRT 20 ml twice weekly, Cialas 3 mg - No Erectile Dysfunction - Doing Well!

james1947

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Re: CD47 antibody phase-1 clinical trial
« Reply #4 on: April 20, 2017, 08:20:19 PM »

Let's hope they will go fast forward with the trials :)

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

Christopher1

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Re: CD47 antibody phase-1 clinical trial
« Reply #5 on: April 20, 2017, 10:08:29 PM »

Good stuff.
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Snake Diet + 5-day fasts + pentox + NeoV's stretching routine. Curvature 99% gone.

I also recommend an auto CPAP device --> increases REM sleep --> increased nocturnal erection.

hope794

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Re: CD47 antibody phase-1 clinical trial
« Reply #6 on: June 20, 2018, 07:35:07 PM »

Really interesting! So, can it reverse existing fibrosis?
Logged
26 yo from Italy.
Peyronie's since abt 2014
Abt 20-25° bend, w/ a moderate twist to the left
Erectile Dysfunction for 4 years and getting worse
From pornstar-like to moderately depressed - still fighting for a solution.

hope794

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Re: CD47 antibody phase-1 clinical trial
« Reply #7 on: May 17, 2019, 07:34:50 PM »

Any news?
Logged
26 yo from Italy.
Peyronie's since abt 2014
Abt 20-25° bend, w/ a moderate twist to the left
Erectile Dysfunction for 4 years and getting worse
From pornstar-like to moderately depressed - still fighting for a solution.
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