Low Dose Pentox in Acute Phase?

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frank_a_c

Hey All,

I am feeling some strong side effects from Pentox. Mostly flushing, tingling, and lightheadedness, a detached and anxious feeling, but when I try to sleep, that's when it gets bad. I get insomnia and some really bad thoughts, as well as a tingling sensation in my head. When this happens, it's impossible to sleep.

I am in the acute phase of peyronies and am taking 2 400mg pentox per day.

I would love to be able to just stop the progression of this disease as my deformity is not too bad at the moment, so I very much want to keep taking it, but I'm a little scared by this and don't know if it's sustainable for the recommended six months or so.  

Do you think that just one Pentox per day could even provide any benefit? I weigh about 142 lbs.

**Update**
Hey all, I wanted to  post and update so as not to make anyone starting out on Pentox nervous: I am now three weeks in to taking two pills per day, and the side effects have leveled out greatly. I am able to sleep and function normally (reminder that I suffer from insomnia and anxiety regardless of meds). There is still the occasional "druggy" feeling, but it is minimal and does not interfere with my life. Again, I am only 140lbs so I think for now I will stick with two rather than three per day.

I can also say that I have noticed the flaccid penis has softened and seems healthier throughout the day. Pain is still present but is definitely reduced. Too early to tell if it will have a benefit on my deformity but so far I am thankful to be on this drug.

Thanks.  

NeoV

It should absolutely have an effect, and at that weight it seems very reasonable to use less. Why not?  

james1947

Frank

To Pentox side effects (I had them also):
* Start taking one 400 mg per day until the symptoms are gone. Increase to 2*400 mg and later to 3*400 mg
* Take always with meals
* Drink a lot of water
* Last not later than 6 PM
Adding low dose Cialis and VED (carefully not to over-pump) will help arresting the disease
Hope my advice will help, I got this advice from George and it helped me.
By the way 142 lbs is low just if you are taller than 5' 8"

James
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe ED.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

frank_a_c

Thanks James - I saw your previous advice to me on this and followed it! At first, two per day was fine, and then it started to feel like it was "building up" in my system.

I know, I'm a pretty skinny guy. I work out a lot and lift weights, but i am 6' tall and 142lbs. I had a goal this year to put on maybe 10 lbs, but then Peyronies hit and I lost focus.  

I had a psychotic break / panic breakdown while traveling abroad about a year ago, and frankly I think the anxiety inducing aspect of Pentox is playing on that predisposed tendency. Any drug with even the slightest ability to induce anxiety, including coffee, is dangerous for me. That said, I need to remind myself it's not the Pentox making me have anxiety, it's me giving myself the anxiety. The Pentox just primes the brain for it chemically. With that in mind, I'm hoping that I can keep it in perspective and work through it.

Given my size, the minimal deformity, and fact that I'm in the acute phase, I think i'm going to stick with 2 Pentox per day rather than three. I just want to arrest the progress, I don't need to reverse it. I saw that one of the acute studies was based on two per day so I have fingers crossed that it will still have a benefit.

Thanks a lot for the responses.  

vinnylid

frank_a_c
I take 400mg Pentox twice a day with food and do not notice any side effects. One thing I have taken for years for anxiety is the amino acid Taurine 500mg. The Life Extension Foundation has done a lot of research on its neurotransmitter properties. It is very subtle, but has worked great for me. I use the Country Life brand tablet.

frank_a_c

As a follow up, I've been handling the two per day better for the past several days. There is still some insomnia and anxiety, but by keeping it in perspective and knowing it cant hurt me, and reminding myself that this drug can make a difference in the acute phase, I'm managing. For anyone dealing with this, I recommend getting up early and taking one (around 6am or so) and taking another perhaps around 1pm, and that's it - if you're taking only two.

Cole Trickle

I just started taking Pentox yesterday and am already having these same side effects.  I feel very detached, disoriented, and can't focus on work very well.  I'm also feeling flush, had some minor tingling around my lips, and have some aching from behind my eyes.  Will this level out within a couple days?  If not, I'm not sure I can take this med.  It's 2:50PM now and all this has happened from taking one 400mg pill at 7:00 last night, and then another pill at 10:30AM with a light breakfast (I'm not a big breakfast eater). I hope these symptoms subside soon or it's going to be no Pentox for me....  Like the OP, I'm a very anxious person by nature who is very sensitive to any changes in my body.  I'm currently on a small does of Klonopin and Mirtazipine to help control my anxiety disorder.  

james1947

Never take Pentox after 6 PM
Never take Pentox without food
Drink a lot of watter
For me, the symptoms on 400 mg Pentox were gone after 1 week, increased to 2*400 mg for 10 days and then to 3*400 mg per day

James
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe ED.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

frank_a_c

Hey guys,

I'm three months in now to taking the two Pentox and have to say that for some people, there may just be no way around the side effects, no matter how carefully you taper up, take only with food, and space the doses. It is rare for me to feel "nothing" on this drug, even taking it in the middle of large meals and being very regimental timing. I am still able to get through the day and do my job, but would be lying if I said that I was not feeling detached and abnormal.

Still, I am going to power through one more month to finish out a whole four and hopefully stop the progression of this disease as I'm in the acute phase.



james1947

Sorry to hear that Frank
Some have problems even with 400 mg daily, some taking 6*400 mg daily and have no symptoms
That is the case with Pentox

James
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe ED.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

frank_a_c

For those struggling on Pentox, this might be useful: I have made some adjustments to my oral regimen and it seems to have helped.

As a refresher, I was on Pentox 800mg per day for four months and basically that four months is a little blurry. I never felt natural. Occasionally I felt awful. Usually I was able to sleep but not always. I spent a lot of time being on edge, anxious, and generally detached.  

Last week I had enough and I went down to one pill. I feel much, much better. The stress has lifted away, and overall I feel much more myself. I guess I am just mentioning this in case anyone else is having trouble on Pentox.

Last thing: While on pentox, I stopped taking Acetyl L Carnitine because it can cause some anxiety too. I have added 2 grams per day of this and have noticed an almost immediate benefit. My penis is fuller and I am getting really strong nighttime erections.

Currently I am taking:
400mg Pentox
400-600mg coQ10
2 grams L-Arganine
2 grams ALC
And this seems to be helpful for me. I still definitely have peyronies and it seems to be progressing, but the pain is not too bad, I don't have much hard flaccid, and generally my dick is bigger, fuller, and softer all the time and I have nighttime erections. I guess what I'm saying is I'm not sure if I'm cured or even if it's stopping the progression, but the above combo has certainly made a difference.

I know that the ideal is to take 1200 pentox, but I am one who just can't, sadly. So if you can't, this breakdown seems to help, at least for me. I weigh 145lbs.