27 years, Peyronies Disease diagnosis

[Laveley]

Hi.

I'm 27 and been diagnosed with Peyronies Disease some months ago. About october/september last year felt a nodule inside my penis, on the left side. No pain and no bend. Went to urologist, long story short; he failed to diagnose me with a serious Peyronies Disease case and just prescribed me with colchicine after another small plaquete appeared near the base of my penis, on the center.... no result with colchicine.

This second plaquete is the only one that really bothers me.... my penis was naturally bent to the right side and the left plaquete only seemed to have straightened him  ... the second one however started to cause an upward bent on about 20 to 30 degrees.

There are two visible dents in the plaquetes area when erect... small pain.

Went to another uro last week, a specialist in the area. Prescribed me with colchicine (again), pentoxifiline and vitamine E.

Colchicine is causing me diarrhea and i think pentoxifiline is causing some skin bruises (i dont know how to describe it in english).

Started with verapamil injection treatment too, already took one last week, right off the bat. Felt a slight improvement in the newest and smallest plaquete, but not on the bend. No side effects either (not a single bruise and swelling just for a day). Going to take the second shot tomorrow.... we planned five. He promised me a 50/50 chance to solve the bend (which bother me the most), but said that the plaquetes hardly will disappear.

Worst case scenario he said treatment will prevent that the disease worsens... which is fine with me i guess, i can live with my penis as he is right now.

My mother said my deceased father had a bend on his penis when he was on his 50's, but it seems that it went back normal naturally with time. Seems like he was a lucky one. My doctor said probably my Peyronies Disease is from genetic origins.

I will post the result of my treatment as it progrides here... can i post images of my penis (i dont care, nobody will recognize me anyways) so people can see the results (or lack of)?

Sorry for the bad english, is not my natural language.

[NeoV]

Welcome to the forum!

I highly recommend traction for reducing the curve and or dents in your penis. You can use a device or your hands to do this, but do it with extreme caution. Read up and see what you can learn on these forums.

Verapamil injections have not been used with much success here on the forums, and a recent study showed that it had the same result as saline injected into the penis.  

[Jimbruski]

Laveley,

Yes, welcome to the forum.  I've only been a member for a week and I've already learned so much from perusing the forum and reading the posts and experiences of the other members.

Be sure that you go to a urologist with experience treating Peyronies.  As NeoV said, Verapamil is an old approach to curing this disease.  New treatment methods are available which will likely give you better results.

Good luck,

jimbruski  

[Laveley]

Verapamil injections have not been used with much success here on the forums, and a recent study showed that it had the same result as saline injected into the penis.

Can you point out this study so i can read it? Thanks.

Will sure check the other treatments in the forums.

[NeoV]

Effect of intralesional verapamil for treatment of Peyronie's disease: a randomized single-blind, placebo-controlled study. - PubMed - NCBI

This study.  

[Laveley]

Interesting.... but this study isnt new, its from 2009. Furthermore, its from Iran....

There are a lot of other studies in pubmed that shows positive results from verapamil injections, the newest one i could found is this one; Intralesional Injections for Early Peyronie Disease: Standardized Assessment and Analysis of Predictive Factors for Treatment Response. - PubMed - NCBI

If you read it you will see its a much more qualified study than the one from Iran. It also shows that the treatment seems to work better on younger people, which is my case.

Also, i have some thoughts on why people on this forums seem to have "no results" with the treatment. But i will wait and see my own results and post it in the correct area of the forums with my opinion on the matter as soon as i finish the treatment. I took my second shot yesterday.... no side effects yet, no bruises and the swelling goes away within a day. In fact, the pills are giving me much more bad side effects like diarrhea and hives on the skin (think i found the word for it).

As for the traction treatment, talked with the doc and he recommended it too. He mentioned a doctor from New Orleans that advocates for this treatment. The only problem is that he said it can be difficult to buy a good traction device here in my country (he said some of them dont stick very well)... i may have to import it from the usa. I still have to do some research thought so i may found a good device here.

[Jimbruski]

Laveley,

Thanks for responding and I share your frustration over this disease.  I can only share my story and muddy the waters a bit more.

I saw a reputable urologist who diagnosed Peyronies Disease. He was very interested in the disease and took a good deal of time diagnosing and then perscribing treatment.  We talked about Verapamil but he talked me into waiting a couple of months and try the newest drug, Xiaflex.

I had two separate rounds of shots with Xiaflex and did the accompanying stretching (by hand) that is suggested by the manufacturer.  All of this produced zero results.

Then I discovered this forum and was amazed at all of the different treatments available for Peyronies Disease, however, nothing seemed to be a "one size fits all" when it comes to curing this menacing disease.

And this is the reason for your and mine and many others frustration with Peyronies Disease.  You feel as if you are chasing your tail trying to nail down the correct course of treatment.  That I can see, there isn't one.

Good luck on your Verapamil injections.  I hope that they work for you.  Please do keep this forum updated on your progress.  We too are waiting for success stories in hopes that we can nail down the elusive cure.

As for me, I'm going to a very well known urologist who specializes in Peyronies Disease.  His name is Dr. Lue and his practice is located at the UCSF Medical Center (San Francisco).  My appointment is in July and I intend to share my experience with the forum also.

Jimbruski

[NeoV]

Certainly, always read studies yourself, try the treatments, and if you don't mind share your results here.

I know verapamil was shown to help based on several other studies, but I am not sure if it is much more helpful than anything else injected into the penis. Even PRP seemed to help me for the first 9 months. Now, nothing.

Even so, I think the science seems like it could help, and any one single therapy never seems to help many so a combination would be wise so you are on the right track. The fact that you are doing something, rather than nothing, is surely to help you.

Traction has a great record and is slowly being established as a standard for the disease along with pentox and nitric oxide raising supplements such as citrulline and drugs such as Cialis (increase nitric oxide via a different means).

Colchicine may have some bothersome side effects, and isn't too favored here but certainly could be worth trying. I am forgetting the study on it by now.  

[Laveley]

Small update; i know its too early to gather results but i measured the bend yesterday, one day after the second injection and the curvature decreased from 36º after the first injection to 30º now! I'm very happy   if the earning continue this way it might be able to reduce the bend to almost not noticeable size.

I also noticed that the plaques get considerably "softer" after each injection.

Just ordered my traction device yesterday too, it will be fortunately in my hands in 15 days, i plan to start the treatment asap.

NeoV, my doc gave me prescriptions for 2 months of pentox. In you experience, how much time is needed for pentox to produce some result?

[Jimbruski]

Laveley,

Great news.  What type of traction device did you order?
Hope all continues to improve for you.

Jimbruski  

[QuackAttack]

Laveley,

I am on Pentox and my URO said it would take 4-5 months to see results using Pentox and traction, no less than 4 hours a day. Since getting the Phallosan Forte, I have upped my traction time from 4 hours to 8-10 hours because it is much more comfortable.

[Laveley]

QuackAttack, thank you for the response. I imagined that the treatment would be this long... this disease seems to be a long term battle... anyways, my doc probably will give me more prescriptions in the future, and if he dont, i will ask for it.

Jimbruski, about the traction device, i bought one that is made here in Brazil, it is from the traditional model. I though it was a fair price and comes with a lot of pros, like foam on the string and the tube for more comfort, an they even to a gold rolling device for people who have nickel allergy, etc. Consulted the doc about it and he gave his OK too, since he recommended the andropenis brand for me and this one is basically equal to andropenis (with the props of being national made).

I took a look on the phallosan one that quackattack and others mentioned here on the forums. I though that it looks a bit clumsy... anyways, i would have to import it at an outrageous price and God knows how long it would take to the product get here. So, if i cant adapt to the one that i bought, maybe i will get another look in the phallosan one, for now, its like a backup plan for me.