The Prevalence of Peyronie's Disease

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Dros

This is a very interesting study:

"Peyronie's disease (Peyronies Disease) is a connective tissue disorder which can result in penile deformity. The prevalence of diagnosed Peyronies Disease in the United States (US) has been estimated to be 0.5% in adult males, but there is limited additional information comparing definitive and probable Peyronies Disease cases. We conducted a population-based survey to assess Peyronies Disease prevalence using a convenience-sample of adult men participating in the ResearchNow general population panel. Respondents were categorized according to Peyronies Disease status (definitive, probable, no Peyronies Disease) and segmented by US geographic region, education, and income levels. Of the 7,711 respondents, 57 (0.7%) had definitive Peyronies Disease while 850 (11.0%) had probable Peyronies Disease. Using univariate logistic regression modeling, older age (18–24 vs 24+) (OR = 0.721; 95% CI = 0.570,0.913), Midwest/Northeast/West geographic region (South vs Midwest/Northeast/West) (OR = 0.747; 95% CI = 0.646,0.864), and higher income level (<25K vs 25K+) (OR = 0.820; 95% CI = 0.673,0.997) were each significantly associated with reduced odds of having a definitive/probable Peyronies Disease diagnosis compared with no Peyronies Disease diagnosis. When all three variables were entered in a stepwise multivariable logistic regression, only age (OR = 0.642; 95% CI = 0.497, 0.828) and region (OR = 0.752; 95% CI = 0.647, 0.872) remained significant. This study is the first to report Peyronies Disease prevalence by geographic region and income, and it advocates that the prevalence of Peyronies Disease in the US may be higher than previously cited. Further, given the large discrepancy between definitive Peyronies Disease cases diagnosed by a physician and probable cases not diagnosed by a physician, much more needs to be done to raise awareness of this disease."

PLOS ONE: The Prevalence of Peyronie's Disease in the United States: A Population-Based Study