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Author Topic: Pentox, 6 doses a day?  (Read 1470 times)

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Pressure

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Pentox, 6 doses a day?
« on: December 08, 2015, 08:48:03 PM »

Hello everyone,

After noticing a 5 degree worsening of conditions, I've decided to up my usual 3 x 400mg a day pentoxifylline to 6 a day, being of younger age and suffering no side effects even taking with no food before bed, I think now's the time to hit the plaque with the best dose, even if it wasn't 5 degrees. It may even get better, it's nearly been 10 months since initial injury, so I may as well throw a lot at it, while it's still, hopefully, not calcified.

What do you think is better 3 doses with food (each dose 2 x 400mg), or 6 doses (each 400mg) spaced out during the day, 3 with food, 3 without?

If you Google "pentoxifylline absorption" there's an interesting drugs.com article.

Quote:

"Pentoxifylline is almost completely absorbed. Food delays absorption and increases Cmax by 28% and AUC by 13%. Tmax is 1 h (parent drug and metabolites)."

Have been reading about Cmax and AUC (quite tricky to understand) but I think food helps absorption. Can someone make sense of the absorption bit?

Thanks for all help.
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james1947

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Re: Pentox, 6 doses a day?
« Reply #1 on: December 11, 2015, 07:01:31 PM »

Pressure

I will not take Pentox without food and not later than 6 PM, but is me.
In my opinion take 2*400 mg with meal 3 times a day
or 400 mg with meal 6 times a day
From many posts on the forum I understand that people were prescribed 2*400 mg 3 times a day with meal.

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

Pressure

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Pentox with no food, long term side effects?
« Reply #2 on: December 13, 2015, 04:21:06 PM »

Thanks James for that, I am wondering if am opening my self up for problems in the future if I have pentox without food 3 times a day? (Still have zero side effects)
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james1947

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Re: Pentox, 6 doses a day?
« Reply #3 on: December 13, 2015, 09:34:37 PM »

Difficult to answer to this question pressure.
Why not just take with food?
You should monitor your white blood cells level from time to time to see if Pentox does not effect your immune system.

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

postrocker

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Re: Pentox, 6 doses a day?
« Reply #4 on: December 17, 2020, 08:50:03 AM »

Hi everyone

I know this is an old topic, but I am reviving it, as I am taking pentox with food.
Anyone thinking that without food would be better?
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34yo
Congenital curvature plus injury during sex - dec.2019
Curve to the left increase plus pain ~35degrees - nov.2020
Pentox (400mgx3) + Cialis (2.5mg/day) + supplements - dec.2020
Traction - jan.2021

pey ron

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Re: Pentox, 6 doses a day?
« Reply #5 on: January 13, 2021, 02:23:51 AM »

I've always taken it on an empty stomach. Probably a mistake since it has a very low water solubility. Also: I went as high as a little over 10 grams a day, watching out for signs of internal hemorrage.
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Asphyxia

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Re: Pentox, 6 doses a day?
« Reply #6 on: April 07, 2021, 10:41:58 AM »

Did anything positive happen from 10 grams a day?
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Age:23. Onset of symptoms: september 2020.
Curve mostly semi erect about 60 degrees, slight pain
Tried short & prolonged fasts, keto,carnivore, traction and most of the supplements.
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