Mediwound MWPC003 for peyronies!

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NeoV

Dared, that's why attacking the scar tissue itself doesn't really fix the issue. You need to improve the health of your tissue, and the cream would do exactly that I imagine. The reason why cialis, pentox, and most treatments work is because they improve the health of your penis itself. VED and traction help expand the penile tissue to "remodel" it and maybe even elongate and grow it. You want to attack penile health, not the scarring really.

Dared

But what I'm saying is true. If all my scars disappeared I would have no penis.

Crooked_Stick

Born 1960, Diagnosed 2013
Initial 40 degree bend, 1" loss, Xiaflex 3 rds of 2 injections
Current 25 degree bend, no palpable plaque, 1/4" loss
VED 5-6 days/week, traction daily,
TRT 20 ml twice weekly, Cialas 3 mg - No ED - Doing Well!

NeoV

Seems cool, since it appears to be a more natural injectable, which we don't have yet. I've been taking bromelain by mouth for a little while now, I really wonder how this will turn out.

properyoung

That is good news, every time I am feeling helpless against this disease, some new development I've overlooked appears. This and Atala's work will probably have us on the edge of our seats for a breakthrough within the next 5-10 years or so. Until then, I think it's best we just do what we can when it comes to general/sexual/tissue health and stay on the radar of the people who develop such things.

(Glad my first post was provoked by something positive :D)

james1947

properyoung

Not to make you bad mood, but 10 years ago Atala was also 5 to 10 years from breakthrough :(
So try whatever you think it may help you in the mean time

By the way, do you have Peyronies?

James  
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe ED.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

properyoung

[Full quote removed]

I do ,hence I am lurking this forum for both support and possibility to make it better with the rest of you. Whether it takes 10 or 20, I just hope me and you can live happy, healthy lives until then.

I've been using VED and traction whenever my penis feels soft and pliable, pentox, coq10, l carnitine and l agranine, also low dose cialis. The combination of the said treatments seem to have stabilised my condition, actually improved it at one point when I was still in the early phase (close to half a year of daily heat, traction, ved, meditation and supplements), but then being an excited young idiot I stopped the protocol, went on a three week holiday, drank, smoked and partied.. and by the time I got back, my peyronies got back to it's beginning stage (leans left when flaccid, hour-glassing at base when erect) and I can't seem to repeat my success that easily(rebuilding my previous unshakeable optimism and discipline as I'm typing this).

Started treatments after around 8-10 months after the appearance of indentations and pain from the injury subsiding.

BTW I am 22(about to turn 23, had peyronies since 20, being hopeful is extremely important to me as it's not just about being able to "perform" during my later respectable years, but rather maintaining as much health and function down there until there is an actual viable treatment)

james1947

properyoung

Pentox, VED and low dose Cialis helped me to stabilize the Peyronies, eliminate hourglasses, gain of some length and girth I lost.
I started the treatment very late, 3 years after the onset I was still with flareups and worsening, still the treatment helped me.
The key is consistency and patience ans the results are coming slowly.
I tried many things, almost everything, just the treatment above helped me.
And yes, we all hope the solution to Peyronies will come soon :)

James
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe ED.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

AlmostBlue

It goes without saying that this is 4-5 years away.That said, those of us posting on this thread will all have late-stage/chronic peyronies by the time this is availalble to us.

I wonder how effective MWPC003 will be against that... I am pretty hopeful given what is known about it so far. I hope it can clear collagen deposits, calcifications, and restore size and shape. Hopefully someone can expand on this.

I imagine for someone who has had Peyronies Disease for a long time (i.e. 3+ years) that multiple injections over a long course of time would be the way to do it. As opposed to a more recent plaque that may dissolve after 1 or 2 treatments. Just my thoughts.

hope794

26 yo from Italy.
Peyronie's since abt 2014
Abt 20-25° bend, w/ a moderate twist to the left
ED for 4 years and getting worse
From pornstar-like to moderately depressed - still fighting for a solution.


Crooked_Stick

Mediwound made a strategic decision to hold off on any further research related to their injectable enzyme until their other two products have completed phase 3. That will take about two years and once those products are on the market they will start some kind of phase 1 and that may or may not involve peyronies. It could easily be 10 years......very disappointing.  
Born 1960, Diagnosed 2013
Initial 40 degree bend, 1" loss, Xiaflex 3 rds of 2 injections
Current 25 degree bend, no palpable plaque, 1/4" loss
VED 5-6 days/week, traction daily,
TRT 20 ml twice weekly, Cialas 3 mg - No ED - Doing Well!

hope794

Where did you read those infos, guys?
Please post the URL.
26 yo from Italy.
Peyronie's since abt 2014
Abt 20-25° bend, w/ a moderate twist to the left
ED for 4 years and getting worse
From pornstar-like to moderately depressed - still fighting for a solution.

hope794

Has someone got new informations? Did someone try to contact them?
26 yo from Italy.
Peyronie's since abt 2014
Abt 20-25° bend, w/ a moderate twist to the left
ED for 4 years and getting worse
From pornstar-like to moderately depressed - still fighting for a solution.

Crooked_Stick

Just an update on Mediwounds' injectable bromelain based drug. I just listened to their lastest conference call:

Q1 MediWound 2019 Conference Call | MediWound

near the end of the call the CEO mentions that they will restart their clinical work. They mention peyronies specifically.
Born 1960, Diagnosed 2013
Initial 40 degree bend, 1" loss, Xiaflex 3 rds of 2 injections
Current 25 degree bend, no palpable plaque, 1/4" loss
VED 5-6 days/week, traction daily,
TRT 20 ml twice weekly, Cialas 3 mg - No ED - Doing Well!

treeza1

Awesome Crooked.. Any notable quotes?

samsung

I just emailed a few people at mediwound. If anyone answers, will post here.
45 y.o. Single. Onset of symptoms (pain-stinging like a wasp) @ 6/2018. No sudden injury. Curve developed slowly. 40 deg. dorsal. Hourglassing. Torsion to left flaccid. 4 rounds xiaflex. Restorex, DMSO+, heat, arginine, cialis, lipoic acid, vit. K2

Fix This

Good work Samsung

Yes, please let us know what they say

Fix
47 , penis trauma July 2018 leading to Peyronies. 30-40 degree dorsal curvature, narrowing after plaque. 

I'm attacking it though, and I will fix this!

VED, traction, DMSO, Ultrasound, Acupuncture, meds, herbs

Fix This

I have also emailed Mediwound on their UK email. I recieved a fast reponse within 12 hours saying that he ( the Account Manager for UK and Ireland ) had forwarded my enquiry to their medical team in Israel for a response.

I'll keep you all posted as soon as they reply

47 , penis trauma July 2018 leading to Peyronies. 30-40 degree dorsal curvature, narrowing after plaque. 

I'm attacking it though, and I will fix this!

VED, traction, DMSO, Ultrasound, Acupuncture, meds, herbs

samsung

I haven't heard anything. Emailed 4 different people there. Will keep trying.
45 y.o. Single. Onset of symptoms (pain-stinging like a wasp) @ 6/2018. No sudden injury. Curve developed slowly. 40 deg. dorsal. Hourglassing. Torsion to left flaccid. 4 rounds xiaflex. Restorex, DMSO+, heat, arginine, cialis, lipoic acid, vit. K2

hope794

Today i emailed too. One year ago an italian doctor replied to me.. I hope that he will reply again.
26 yo from Italy.
Peyronie's since abt 2014
Abt 20-25° bend, w/ a moderate twist to the left
ED for 4 years and getting worse
From pornstar-like to moderately depressed - still fighting for a solution.

samsung

Here is my email and Jeremy Feffer's response:
1
Sorry for the delay in response. As the company has mentioned before, this program is still pre-clinical, but there should be updates next year.


On Sep 1, 2019, at 5:18 PM:


Hello,


Are there any updates about MWPC003? Please check out peyroniesforum.net. I would include links to where mediwound products are discussed but you don't know me, so I'm sure would not want to click on links in an email.


At any rate, many, many men are awaiting news of when any clinical trials might be taking place. Thanks in advance for any updates.


Best,
45 y.o. Single. Onset of symptoms (pain-stinging like a wasp) @ 6/2018. No sudden injury. Curve developed slowly. 40 deg. dorsal. Hourglassing. Torsion to left flaccid. 4 rounds xiaflex. Restorex, DMSO+, heat, arginine, cialis, lipoic acid, vit. K2

hope794

With next year they mean 2020? Let's wait...................

Thanks samsung, well done bro.
26 yo from Italy.
Peyronie's since abt 2014
Abt 20-25° bend, w/ a moderate twist to the left
ED for 4 years and getting worse
From pornstar-like to moderately depressed - still fighting for a solution.

samsung

Yep. I assume he meant 2020. In the meantime, keep on stretching. Don't play ping pong with your ding dong. Lay off the cheeseburgers, smokes and keep your cock away from sharp objects. All will be well.
45 y.o. Single. Onset of symptoms (pain-stinging like a wasp) @ 6/2018. No sudden injury. Curve developed slowly. 40 deg. dorsal. Hourglassing. Torsion to left flaccid. 4 rounds xiaflex. Restorex, DMSO+, heat, arginine, cialis, lipoic acid, vit. K2