GENERAL COMMENTS & Questions - that won't fit under any of our other topics

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Iceman

thanks for the support guys - sometimes this can really overtake you - the pain comes and goes im afraid  - im taking all vits and pentox but have stopped VED usage for the past 2 weeks due to living arrangements as itshard to duck into the toilet for privacy for a quick pump - im moving back home tomorrow and will be back on the ved - maybe this may help - oldman  - your words are ticking over in my mind - ( really agree with what you said - the mind is very powerful)


cowboyfood

Quote from: cowboyfood on May 07, 2009, 12:20:33 AM
Quote from: Angus on May 07, 2009, 12:08:49 AM
Thought I'd jump in... not trying to beat you to the punch jack, but here ya go, cbfood...

Benign prostatic hyperplasia (BPH) also known as nodular hyperplasia, benign prostatic hypertrophy (technically a misnomer) or benign enlargement of the prostate (BEP) refers to the increase in size of the prostate in middle-aged and elderly men.

  Hey cbfood, don't feel bad. I'm 58 but don't look a day over 143  ;D

After everything I've done with my life, now that I am familiar with the term "benign prostatic hyperplasia", I feel officially grown up.

Well, I will explain this to the uro on Tuesday.  Now, I have a list!  Some suggested it might be "stress" related.  I won't bore the board with my story...but, to make a long story short...I've voluntarily put myself under a lot of stress with a career change; which involves law school and living like an indigent at times...plus a very hectic move in between fall/spring semesters last december to a school in Atlanta.

Anyway, I'm so thankful to have this wonderful board to educate me on things I took for granite for so long...my health.

CF

I saw the uro's P.A. the other day and he check out my prostate, said it was normal.  I mentioned the bph (well, I pulled out the pamphlet they had on the wall entitled bph) and mentioned my symptoms, but he quickly dismissed bph... I think my come back was "are you sure?" (pretty lame).  He said yes.

CF
Currently:  L-Arginine (2g), Vit D3)

LWillisjr

Quote from: Smitty on May 14, 2009, 01:00:36 PM
Yeah, after researching the disease for a few years now, I was quite surprised whenever my first urologist visit resulted in the option of surgery being thrown into my face within 15 minutes.

lwillisjr I'll contact you within the next few days. Thanks.

Anyone up for a little humor? My urologist asked me if I have any pain during intercourse, and guess what I told him? I've never had intercourse. He was shocked... 19 years old and still a virgin?

Smitty,
Feel free to email me or PM through the forum. Would be happy to talk by phone as well if you like.

Be proud of your virginity. Sex isn't a conquest of "how soon can I do it". Right girl, right time, and it will happen......  Peyronies or not.

As far as your urologist getting to the surgery suggestion so quickly... keep this in mind. It is the opinion of some urologists that drugs, traction, or VED therapies for Peyronies Disease are only effective during the first 24 months or so. Once the plaque has stabilized it can begin to calcify. Once this happens then surgery (or doing nothing) become your few choices. So depending on your history and when your Peyronies Disease occurred, may explain why your uro got to the surgery option so quickly.
Developed peyronies 2007 - 70 degree dorsal curve
Traction/MEDs/Injections/Surgery 2008 16 years Peyronies free now
My History

bodoo2u

Are you sure BPH does NOT clear up? I'm worried now. What about the meds that they prescribe for it? Don't they help. My uro didin't tell me that i would have it forever and that there is not a cure.

jackp

bodoo2u
You don't want to hear this but BPH is only controlable not curable. Mine started over 35 years ago and in that time I have had 2 TUPR (surgical reduction) and taken some of the meds.
I had been taking Saw Palmetto because of the side effects of the meds and in early 2008 decided that after 10+ years to quit. About 10 days ago I had to have a bladder scope and the doctor remarked that my prostate was enlarging again and wanted me to start taking meds. I politely told him NO that I did not like the side effects and would start back on Saw Palmetto.
Saw Palmetto takes a few weeks to work but it does work. I get mine from GNC along with zinc, copper and other vitamins for men over 50. I tried the big box store brands but they just did not have the quality. Also a glass of cranberry juice every day helps.
Hope this helps.
Jackp

atlantis

Hi,

Any of you guys with BPH or prostatits started having those problems at the same time as the appearing of 'La Peyronie'. The last urologist I saw told me that if the prostatitis would get cured in a few months, 'La Peyronie' would dissapear. All what I have found is some posts  two years ago in the forum by Phil who said that both things appeared at the same time, and at the time he stopped taking the medication for prostatitis, Peyronie disease got much worser.

Any thoughts on that?


bodoo2u

Thanks (for nothing) Jackp  ;D

I'm glad you and a few other set me straight. I have been saying to myself for years that "I'm gonna take this Saw Palmetto like I should, every day, and be rid of this mess." I guess I've only been fooling myself, almost like I have been doing with Peyronies Disease.

Bodoo

UK

I've posted this before but want to put it out again in relation to Prostatis and Peyronie's.
Prostatis is an incorrectly coined term for what today is being termed Chronic Pelvic Pain Syndrome which has nothing to do with the Prostate. Prostatis (bacterial infection) occurs in approx 5% of cases where the symptoms of unrinary difficulty, painful ejaculation etc are present. The other cases are increasing accepted as a result of pelvic floor muscle disfunction due to stress and yes this is where the Peyronie's connection comes in. You will probably be unaware that you are tensing your muscles and this is going to be a hard one to reverse as no pills or surgery can help but you need to learn to relax them and this will take time. Obviously get checked out for Prostate infection, stones, blockages, enlargement but if your Urologist does not find anything then its likely CPPS is what you have.

atlantis

Hi UK,

thanks for the message.  What the last doctor told me was that maybe Peyronie and 'prostatitis' were associated, and curing prostatitis may make Peyronie's dissapear. He gave me the CIPRO 500 for 10 days, and even suggested surgery for the prostate, which makes me frightened. In any case the 'tensing muscles' history fits in my case, as I have had anxiety and stress problems for many years.


Shortie

Hi All,
Stopped by to say hello. My sex life is still almost non existent. I check in now and then hoping to see if a 'cure has been discovered". Maybe next time.
Regards,
Shortie

UK

Atlantis, I strongly recommend reading "A Headache in the Pelvis" by David Wise.
It will give you a lot of answers.

atlantis

Yes, but the doctors do not seem to like the idea of stress producing those symptoms and continue to give antibiotics.

Quote from: UK on May 22, 2009, 02:45:02 AM
Atlantis, I strongly recommend reading "A Headache in the Pelvis" by David Wise.
It will give you a lot of answers.


phil

Atlantis,  i have come to the realization that my prostatitis is really chronic pelvic pain syndrome.  i also have Peyronies Disease and i think getting Peyronies Disease started and continues the cpps symptoms>  i have had pelvic floor testing and exercises and they seem to help> the wikipedia site on cpps has some good info. i guess i've learned to live with both.  hoping to get xiaflex one day.

George999

Phil,  I would suggest that this is really just another inflammatory syndrome that is auto-immune at its root, and thus related to Peyronie's in this way.  I was getting treated for urinary tract problems for years only to eventually discover that most of it was inflammatory and not bacterial.  The only issue with this that is of concern is that chronic inflammatory syndromes can foster or hide bacterial infections.  This makes it really important to try to keep them under control.  - George

Hawk

Hunter,

I read your very thorough and well written post in "Our Histories"
Quote from: Hunter on June 01, 2009, 02:16:32 PMHunters history and background with Peyronies Disease

Since that "Our Histories" area is reserved only for Histories and not two way conversation I thought I would reply here and link to your story.

I want to welcome you to the forum and thank you for contributing by already posting.  I hope you find both the information and support you seek.

Regards

Hawk
Prostatectomy 2004, radiation 2009, currently 74 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

RichB

Is it possible to be able to get normal, regular, stimulated erections in the daytime but no night time erections?

I know that if you get night time erections then most doctors say you can get them in the daytime, but I have been wondering if the inverse is true, because I may have that.

How much of an effect does irregular night time erections have?

newguy

RichB - As the mechanism between the two differs, I certainly think that it's possible to be able to gain stimulated erections in the day, but partially or completely lack night time erections. My night time erections are currently irregular, whereas day time erections are not as much of an issue for me.

My belief is that we should try to replicate what would typically occur in males without sexual health problems. Therefore lacking night time erections is not ideal by any means, probably makes fibrosis more likely, and can be indicitive of ongoing sexual health issues.

Thankfully viagra and co can be helpful for day and night time erections, and Trazodone is apparently a cheap and powerful drug with the ability to induce nocturnal erections at low doses. These substances should allow people to cater an approach which suits their particular needs.

Use of the VED has also been shown to reduce erectile dysfunction and fibrosis in those following penile surgery. Of course peyronie's is 'a different kettle of fish', but I believe that it may possibly discourage erectile dysfunction in those with peyronie's, which in combination with the oral treatments is likely a good multi pronged approach to dealing with lack of erections.

YoungOne

First, I know that this disease sucks no matter what shape, size, form, degree, stage, etc. But, I am wondering if having a plaque in one area is worse than another? I am scared I will slowly lose length over the next year. My injury happened a little over a month ago and I have seen literally no improvement.

In other news, My family doctor prescribed me to cymbalta (antidepressant) after telling him about my history struggling with anxiety. I don't think I am going to take it because I doubt it is good to take with L-Arginine, Vitamin E, and Multi V daily. I took a sample today and it made me feel like crap. All i wanted was xanax but of course, doctors dont like writing xanax scripts for 23 year olds. He did give me a 0.25mg xanax prescription.....wow, how worthless.

jeffturner

Men with Peyronie's disease usually seek medical attention because of painful erections and difficulty with intercourse. Since the cause of the disease and its development are not well understood, doctors treat the disease empirically; that is, they prescribe and continue methods that seem to help. The goal of therapy is to keep the Peyronie's patient sexually active. Providing education about the disease and its course often is all that is required. No strong evidence shows that any treatment other than surgery is effective. Experts usually recommend surgery only in long-term cases in which the disease is stabilized and the deformity prevents intercourse.

Mick

Your statement, "No strong evidence shows that any treatment other than surgery is effective" indicates that you haven't read much on this site, not even the Child Board.  Please do so before posting again.  Pay special attention to the VED thread.  

Hawk

There is strong indication that Jeff Turner may be a SPAM account to push a commercial site.  If so he will not be here long.  If he is not, then we welcome him and Mick's advice stands.
Prostatectomy 2004, radiation 2009, currently 74 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

cowboyfood

Quote from: Hawk on June 11, 2009, 12:12:37 PM
There is strong indication that Jeff Turner may be a SPAM account to push a commercial site.  If so he will not be here long.  If he is not, then we welcome him and Mick's advice stands.

A big thank you to Hawk, Old Man, Angus, Mick, and newguy for monitoring the forum and, IMO, appropriately remedying any illegitimate posts.

IMO, although there is a legitimate interest in allowing guests and members to post information, there is, IMO, another legitimate interest in identifying or removing posts not made in line with the forum's policies and expressed intent because these posts can cause high anxiety and discouragement with many forum members and guests, especially those that are in their beginning stages of trying to understand the condition.  I believe this is true because of my own, personal experience in using our forum.  In these situations, I believe the latter interest significantly outweighs the former interest.  

As a mentioned to Old Man in a private message, posts and naked assertions that appear to be made with mere animus should be subject to removal at the discretion of the forum's moderator in order to serve the interest of eliminating unnecessary anxiety and discouragement amongst the forum's readers, regardless of the post's content.  

IMO, any legitimate and relevant information removed by the moderators is more likely than not to be posted in the future in the appropriate manner.

CF
Currently:  L-Arginine (2g), Vit D3)

newguy

There was a post elsewhere concerning whether it's good to stretch the penis (via erections) following an injury. I found a link to this study on the forum and thought I'd remind people of it again here because I managed to miss it first time around:

https://www.peyroniesforum.net/index.php/topic,25.msg10695.html#msg10695

Another study I found involving stretching tissue and the inhibition of TGF-B1:

QuoteOur understanding of the pathophysiology of the overactive bladder is poor. It has been proposed that localized contractions result in the abnormal stretching of bladder smooth muscle. We hypothesize that stretch regulates the cellular processes that determine tissue size. The purpose of this study was to investigate the effect of stretch on apoptosis, proliferation, cell hypertrophy, and growth factor production in human bladder smooth muscle cells in vitro. Normal human detrusor muscle was obtained from patients undergoing radical cystectomy for invasive bladder cancer, and primary cultures were established. Cells were mechanically stretched on flexible plates at a range of pressures and times. Apoptosis was assessed by propidium iodide incorporation and flow cytometry. Radiolabeled thymidine and amino acid incorporation were used to assess proliferation and cell hypertrophy. ELISA and RT-PCR were used to assess growth factor production. Mechanical stretch inhibits apoptosis in a time- and dose-dependent manner and was associated with increases in the antiapoptotic proteins heat shock protein-70 and cIAP-1. Stretch also increases smooth muscle cell proliferation and hypertrophy, but hypertrophy is the more dominant response. These changes were associated with increases in IGF-1 and basic FGF and a decrease in transforming growth factor-beta1. Mechanical stretch regulates apoptosis, proliferation, and cell hypertrophy in human bladder smooth muscle cells.
- http://www.ncbi.nlm.nih.gov/pubmed/12388384?ordinalpos=16&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

This study (http://www.ncbi.nlm.nih.gov/pubmed/11278731?ordinalpos=19&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum) suggests a very different outcome in relation to differing stretch pressure.

I thought I'd place this in the general area, as it relates to multiple areas of treatment (VED, traction, natural erections etc)

Cowboyfood - thanks :)

RichB

Could someone please explain what corporal fibrosis is and how it can develop from peyronie's? I am always slightly afraid that it is constantly developing. I have lost length, but I am not sure if it is from the Peyronies Disease or CF.

jackp

Corporal Fibrosis -- where the tubes of penile "spongy tissue" that maintain erection are gradually replaced by inactive, fibrous scar tissue.  The disorder occurs when the penis' sensitive spongy-tissue cells don't get the oxygen they need to survive, usually because of a chronic reduction in blood flow.

In my case it was caused by sleep apnea then severe venous leakage.  Trimix injections for ED made it worse.

The pills for ED V, C, L do not help. Regular VED exercise helps keep the penis healthy but the only successful long term treatment is a penile implant.

Jackp  

RichB

So, in order to prevent that from happening, what would one do? Did you have Corporal Fibrosis before you had Peyronies Disease? I understand many members haven't developed the condition, my example being Old Man having the disease since he was young. My concern is that since I am young the possibility of developing it slowly over the years since I have a long life ahead of me. I am thinking it would be better to talk to a urologist about this. It seems that you JackP are the only member I have seen that has spoken strongly about it, and the only member I've seen that truly knows that's what he had instead of just speculation. I want to know how many other members have been diagnosed with Corporal Fibrosis after they developed Peyronies Disease.

George999

Note that Pentoxifylline which is used to treat Peyronie's has the capability to prevent corporal fibrosis and, in fact, has been used to treat corporal fibrosis.  Alagebrium may also be useful in the case of corporal fibrosis.  - George

jackp

RichB
I did not have corporal fibrosis before peyronies. To prevent it Do Not Stick A Needle In Your Penis For ED Shots!!! Make sure you have strong night time erections and follow the VED exercise recommended by Old Man.

Mine happend after severe venous leakage and using trimix shots for ED. It also increased penile shrinkage.

If you can find a Male Sexual Function doctor, not just a general practice urologist, he would be the best for treatment.

IMHO Peyronies with ED is when my problems started. Shots make it worse!!!

My cardiologist said no to pentox or any other supplements. I was on Plavix and then Warifian.

Jackp

RichB

Does anyone have any information regarding the hinge effect and how to treat it? It seems that due to my injury, the part that softens and doesn't hold an erection happens to be my entire penis...


EDIT: Are there any cases of atypical peyronie's on this site? Any information on how they turned out or of them getting better/worse?

ocelot556

I seem to remember hearing the VED credited with helping reduce or remove the hinge effect in some sufferers, Rich.

jackp

RichB

Can you clarify your hinged effect? The way I read your post is that all of your penis remains soft, not just from the point of injury.

Jackp

Hawk

Quote from: RichB on June 17, 2009, 05:02:12 PM
Are there any cases of atypical peyronie's on this site? Any information on how they turned out or of them getting better/worse?

How are you using the term and what makes you think your Peyronies Disease is atypical (if that is what you are suggesting)?
Prostatectomy 2004, radiation 2009, currently 74 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

RichB

Hawk,

From what I have seen, "atypical" Peyronie's is designated as plaque that has grown in the septum of the penis between the two cavernosa. What makes it atypical is that there are all the classical symptoms of Peyronies Disease but no obvious plaque.

JackP,

When I get an erection and feel below the base of my penis, the tissue underneath is firm, hard, and feels like it always did when getting an erection and when I palpate it. Past this point, the tissue during an erection is soft, unable to hold an erection well, and what I can describe as "spongy." What is also notable is that the penis is easily moved back, forth, and all around, instead of just staying at one point when erect. It also does not stay at a specific angle when erect.

Hawk

Quote from: RichB on June 17, 2009, 09:33:43 PM
From what I have seen, "atypical" Peyronie's is designated as plaque that has grown in the septum of the penis between the two cavernosa. What makes it atypical is that there are all the classical symptoms of Peyronies Disease but no obvious plaque

You raise more questions than you provide answers.  First, where did you get that definition of atypical Peyronies Disease.  I do not know that there is much in the way of typical (expected) plaque placement for Peyronies Disease.  Plaque can be in any configuration on the tunica, and occurs in the cavernosum, and septum. or on all three.  To me, Peyronies Disease is so individual in the trigger that causes it, the progression, the various stages, the deformity, the response to treatment, that I have no clue how one could declare a case typical or atypical (unexpected characteristics).  

Secondly, a large percentage of Peyronies Disease patients have no palpable plaque.

I guess what I am saying is that I reject that use of the term "atypical" until I see it as a standardized definition used by a large percentage of Peyronies Disease practitioners.   I have never seen that definition clearly explained by even one well know practitioner.
Prostatectomy 2004, radiation 2009, currently 74 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

RichB

I base my definition of atypical on this link: http://www.medicalnewstoday.com/articles/62103.php

I call them as I see them. I understand what you are saying though, I'll keep it in mind with future posts.

newguy


in mouse Subcutaneous Connective Tissue...

I recall I while back I asked whether it would be useful for people to use the VED  following a peyronies diagnosis if pain was still present. While this isn't strictly an answer to that, it is an interesting study which suggests that directly after receiving an injury it may in fact be very beneficial to stretch. In may be a windows of opportunity type situation, but it does perhaps offer an insight into one mechanism by which the VED and even pre-emptive stretching (for those with peyronies but no or little curve as yet) could be useful, and perhaps how gradual remodelling or recover can occur where defortity is already present.

If a person is in pain it is perhaps their natural inclination to rest until they are healed. In some conditions this is likely true, but in peyronie's the inflammatory cascade is already in motion, so in my view stretching by daytime and night time erections AND VED use or light traction is as important as oral treatments.

QuoteTransforming growth factor beta 1 (TGF-b1) plays a key role in connective tissue remodeling, scarring, and fibrosis. The effects of mechanical forces on TGF-b1 and collagen deposition are not well understood. We tested the hypothesis that brief (10 min) static tissue stretch attenuates TGF-b1-mediated new collagen deposition in response to injury.Weused two different models: (1) an ex vivo model in which excised mouse subcutaneous tissue (N¼44 animals) was kept in organ culture for 4 days and either stretched (20% strain for 10 min 1 day after excision) or not stretched; culture media was assayed by ELISA for TGF-b1; (2) an in vivo model in which mice (N¼22 animals) underwent unilateral subcutaneous microsurgical injury on the back, then were randomized to stretch (20–30% strain for 10 min twice a day for 7 days) or no stretch; subcutaneous tissues of the back were immunohistochemically stained for Type-1 procollagen. In the ex vivo model, TGF-b1 protein was lower in stretched versus non-stretched tissue (repeated measures ANOVA, P<0.01). In the in vivo model, microinjury resulted in a significant increase in Type-1 procollagen in the absence of stretch ( P<0.001), but not in the presence of stretch ( P¼0.21). Thus, brief tissue stretch attenuated the increase in both soluble TGF-b1 (ex vivo) and Type-1 procollagen (in vivo) following tissue injury. These results have potential relevance to the mechanisms of treatments applying brief mechanical stretch to tissues (e.g., physical therapy, respiratory therapy, mechanical ventilation, massage, yoga, acupuncture).
-  
http://www.ncbi.nlm.nih.gov/pubmed/17654495

A quick check revealed that this was posted a while back, but I see no reference to the entire detailed report which makes for very interesting reading:
http://www.emba.uvm.edu/~iatridis/me208/langevin_JCP_2008.pdf


newguy

From the pdf in previous message:

QuoteTo date, studies of
cultured cells and tissues examining the effect of mechanical
forces on TGF-b1 and matrix remodeling have nearly
exclusively employed prolonged (hours to days) cyclical or
static stretch of low amplitude (less than 15% strain) (Stauber
et al., 1996; Zhuang et al., 1996; Hirakata et al., 1997; Gutierrez
and Perr, 1999; Lee et al., 1999; Hinz et al., 2001; Kessler et al.,
2001; Grinnell and Ho, 2002; van Wamel et al., 2002; Atance
et al., 2004; Sakata et al., 2004; Loesberg et al., 2005;
Balachandran et al., 2006; Balestrini and Billiar, 2006;). Under
normal physiological circumstances, some amount of static
tissue tension or ''prestress'' is present to varying degrees in
different parts of the body while prolonged, repetitive cyclical
stretching of tissues occurs due breathing, arterial pulsations,
and repetitive movements such as walking (Tomasek et al.,
2002; Silver et al., 2003; Ingber, 2006). During wound healing or
chronic pathological conditions such as fibrosis, tissue tension
can slowly increase over days to weeks due to the contractile
activity of myofibroblasts (Stopak and Harris, 1982; Tomasek
et al., 1992; Arora et al., 1999; Grinnell, 2000; Hinz et al., 2001).
It is generally accepted that, when applied over an extended
time period in the presence of TGFb, low amplitude static or
cyclical stretch causes an increase in the synthesis and
deposition of collagen (Leung et al., 1976; Lambert et al., 1992;
Chiquet, 1999; Kessler et al., 2001; Grinnell and Ho, 2002;
Atance et al., 2004; Balestrini and Billiar, 2006). Our results, in
contrast, show that brief, moderate amplitude (20–30% strain)
stretching of connective tissue decreases both TGF-b1
and collagen synthesis. This effect, opposite to that of
prolonged stretch, highlights the critical importance of ''dose''
(i.e., duration, amplitude, frequency) in mechanically induced
connective tissue remodeling.

In contrast to my comments in the previous message, this additional information from the study perhaps suggests that prolonged stretching via traction is in fact a bad idea in the active stage of peyronies. It may in fact increase TFG-B1 and collagen production, in which case it would be more suited to stable conditions. The VED on the other hand fits in well with the use of "brief stretching" (10 mins twice daily in this case) so would probably be more of use during he active stage. Of course this is just one study, but hopefully at some point other information will back it up in future.If not maybe the study isn't of value. How much this info truly relates to our specific situation is anyones guess, but it's a good read and could impact how people approach treatment.

Tim468

Be very careful in extrapolating lab data to humans.

Stretching out a matrix upon which cells are growing in cell culture to determine what "stretch" does to their expression of genes and gene products may be very different than what happens in the body.

Tim
52, Peyronies Disease for 30 years, upward curve and some new lesions.

Hawk

Quote from: RichB on June 18, 2009, 12:27:12 AM
I base my definition of atypical on this link: http://www.medicalnewstoday.com/articles/62103.php

I call them as I see them. I understand what you are saying though, I'll keep it in mind with future posts.

First, I am not asking you to keep anything in mind concerning your posts.  Post what you care to post whenever you care to post within forum rules.  I am just trying to clarify the discussion.  If we attach different definitions to the same terms communication becomes impossible.

The link you posted describes a very small subset with plaque isolated to ONLY the septum.  This plaque seems to be the result of penile injuries that caused a hematoma in this area.  Are you saying you meet all these criteria and that you have been diagnosed with plaque isolated to this one area?

Next, it is my understanding that while the above description would meet the definition of "atypical" (because is not what one would expect), an entirely different set of unexpected developments would also be called atypical.  This means when you ask, "does anyone have atypical Peyronies Disease " that in theory several could correctly answer yes and none of them would share your set of circumstances.  Atypical simply means conditions that are not typical.

Carried to the absurd, an atypical response to hay fever could be that only one nostril became stuffy.  Another atypical response could be that drainage filled the patient's lungs and caused pneumonia.  One patient asking, "who else has atypical hay fever", would not return responses that slightly matched that patients symptoms.

If you have plaque known to the isolated to the septum, you would get more accurate responses by asking, "does anyone have plaque isolated to the septum?"
Prostatectomy 2004, radiation 2009, currently 74 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

jackp

RichB

Do any of the ED pills V, C or L or VED thearpy help?

Jackp

RichB

I have yet to try any of them, but simple L-Arginine has helped, so I am assuming the official pills will too.

newguy

Quote from: Tim468 on June 18, 2009, 08:27:13 AM
Be very careful in extrapolating lab data to humans.

Stretching out a matrix upon which cells are growing in cell culture to determine what "stretch" does to their expression of genes and gene products may be very different than what happens in the body.

Tim

The study in question used both ex vivo and in vivo models.

atlantis


Hi RichB,

do you have the full text of the article in PDF that you can send by email? The journal is only accesible by subscribers.



Quote from: Hawk on June 18, 2009, 09:20:02 AM
Quote from: RichB on June 18, 2009, 12:27:12 AM
I base my definition of atypical on this link: http://www.medicalnewstoday.com/articles/62103.php

I call them as I see them. I understand what you are saying though, I'll keep it in mind with future posts.



RichB

Dear anyone:

If any of you have taken Cirprofloxacin or any FQ drug I would like to talk to you. Please PM me if you have.

-RichB

atlantis

I have just been reading the whole article of teh septal hematomas, here is the link

http://www.jurology.com/article/PIIS0022534706021823/abstract

You just need to go to the link FULLTEXT-PDF and you can access it.  I did not realized but this journal is open access.


The symptoms they describe are quite similar to mine, but I was done two ecography-doppler in flaccid and they told me they found nothing abnormal.

YoungOne

The entire tip (top third when flaccid) of my penis is scar tissue. I still get erections, but they are still kind of painful 2 months post injury. I have not lost size or girth, but is this something I should expect?  Like I said, it is only the tip of my penis. When having sex my penis was bent upwards an inch from the head.

The most worrysome part of what happened is the painful erections, and the fact that I have a circular dent around my penis where the tissue ends. Please tell me it does not progressively get worse/more painful/more curved.

Tim468

Since I now see my count as 1338, then I assume that there is a glitch in the system that turned 1337 into "leet". I do note that the two 3's could look like capital E's, an L as a 1, and a 7 as a T, but it was truly weird to see my post count as "leet". Luckily Hawk noted this and emailed me - so someone else saw it too.

Tim
52, Peyronies Disease for 30 years, upward curve and some new lesions.

newguy


YoungOne - I think it's a  hard one to call, but here's hoping that it doesn't worsen. As you're doing everything you can to keep your penis healthy, then let us hope that there is more chance of a positive outcome!

cowboyfood

All,

I thought I'd offer up some clarification on a person's (located in the U.S.) First Amendment right to free speech.

The 1st Amendment's prohibition on restrictions of free speech only restricts the Federal Government, and state governments via the 14th amendment, from abridging one's right to free speech. (meaning that until the passage of the 14th amendment in 1868, states could prohibit all the speech it wanted!)

However a person's right to not have the government restrict their speech is not unlimited.  Our federal and state governments may restrict our right to free speech for a compelling governmental interest provided it is the least restrictive means to accomplish the compelling governmental interest (for example, incitement, obscenity, child pornography).

The 1st and 14th amendments do not apply to private individuals or entities. Generally, a private entity may restrict speech, despite the fact that the speech is not criminal (gov't can't restrict the speech, but a business can restrict employee speech that is non-criminal).

This forum is a private entity and the 1st amendment is not applicable.

That is why it is perfectly legal for the forum to restrict speech in the manner that it does (In fact, the forum moderator could choose to regulate forum speech arbitrarily!).

According to the forum rules, "anyone suspected of posing as a Peyronies patient to influence a commercial transaction (a shill), is subject to an immediate and permanent ban."

In other words, at the moderator's discretion, anyone "suspected" may be immediately and permanently banned.

So, if I understand the forum rules correctly:
In regards to an alleged Spammer and our forum's speech restrictions,
the issue is NOT whether their purported cure is effective, the issue IS whether they are a shill.

CF

Currently:  L-Arginine (2g), Vit D3)

skunkworks

Are there any diseases similar to Peyronie's which have been studied/experiemented around extensively?

In my research I am finding Peyronie's has not had all that much work done on it over the years, so am wondering if a disease with similar causes and possibly similar treatments may have more info for me.
This is an emotionally destructive condition, we all have it, let's be nice to each other.

Review of current treatment options by Levine and Sherer]