Priapus shot

[incautious]

Loyalty. Interesting about the PRFM. I believe Runnels experimented with fibrin matrix in trying to get a bigger bang so to speak, but I don't know what happened with that. I think that he also was trying HGH too, but can't remember. 1 cm in a week is impressive. I saw immediate increase in girth but took about a few weeks to see an increase in length. Once urologist's embrace  PRP and perfect it , I'm sure that this procedure will be common place for treating Peyronies. My neighbor just had PRP injected into her shoulder. She could not even lift her arm more that a few inches. After a week she could raise her arm over her head. Simply amazing, and she was in a lot pain, and now there is none. So again the theory of PRP is a sound one in helping to heal injury's.  

[IhatePD]

Hi everyone, just a quick update as I have been away since my PRP shots last Wednesday.

The shots were not fun but bearable with the numbing cream. I have a little more plaque on my top left side (all of it is on my dorsal side) and the shot where most of the plaque is located was the most painful. Dr. Varano injected the needle through my plaque and injected the PRP just under it.

I can see a slight increase in girth on my left distal side of my penis where I have narrowing. I did have sex Saturday night, three days afterwards and it was really pretty good without discomfort. I am definately thicker where I had narrowed previously but I would say no effect on the curve yet. I am sure it is too early for it to help.

Unfortunately, I am having a prostate issue right now which is unrelated to the PRP. I had this before and I think it might have indirectly led to my Peyronies Disease. I am bleeding in my urethera where it passes through the prostate. In November 2011, I had the same problem and it is hard to stop because it is caused by the enlarged prostate forcing me to strain the urine through, causing the urethera to scrape and cause bleeding where it passes in the prostate. As it starts to cooagulate, it blocks the urethera and everytime you force urine out it starts bleeding again. Back then, my urologist did a cytoscopy where the put a camera through your penis into your bladder to check for cancer, etc. To begin the procedure, he injects novacaine through the penis and into the bladder and put a "clamp" on my penis to hold it inside me while it takes effect. Six months later, I developed my first sign of Peyronies Disease exactly on the spot the clamp was applied.

So, that is happening right now which really suckds because I am leaving for a five day camp trip on Wednesday and I am not going to be near any sort of medical facilities and the possibility of getting clogged up enough to require a catheter is very real.

[james1947]

IhatePD

Wish you good results with the PRP, keep updating us.
Wish you also to have a pleasant camp with no urinary problems.

James

[NYC]

Can anyone recommend a urologist in or near NYC that will perform the priapus shot? My urologist is clueless about peyronie's.

[james1947]

Directory | Priapus Shot (R)

James

[Chef Chris]

Hi everybody it's bean a while since I have posted but here comes a update. It's bean 4 weeks since my second injection an I finally started to notice some improvement my curve has gone down from a 30 degree dorsal to a 20 degree dorsal and my big plaque on my right side has become smaller and on the left side where I have a long plaque it has dispersed on some of the area. I am feeling confident now that this will work and are planing to do a third injection in July.
I have bean pumping and holding 10 min in the morning and 10 in the evening everyday and I have also bean wearing traction for 3 hours everyday.  

[incautious]

chris, congrats!!! 4 weeks is when is when I started seeing major improvement so hopefully you are on the same track. As noted earlier, my plaque is now completely gone as of my last appointment with my Urologist, so here's hoping that you get the same result. Good luck and God bless  

[james1947]

Chris

Encouraging results.
Keep us updated.

James

[chandnitare]

Chris,

Congrats!

Very much happy for your result.

Did u do VED just after the shot?

Best regards,

Chand

[Chef Chris]

Yes i did I pumped to fully erect and hold it for 10 min

[UrsusMinor]

Well, I've decided to join the crowd and get the shot. I'm not going to do it until late August, as I have a lot of travel until then, and don't think that sitting crunched in an airline seat is good for my junk, whether healing or otherwise.

I'm going to go with Jason Sachman, MD, at Total Male in San Jose, CA. He's done a handful of Peyronie's patients already, including one of our forum participants. (I won't name our forum participant, as he PM'ed me the contact, for which I am grateful. But he's welcome to step up and take credit if he likes.) The Doc is easy to talk to, sounds totally sane, and has even done the injections on himself to make sure he understands the experience. (My hat is off to him in that regard. I wish more docs were self-experimenting.)

I can't guarantee any ultrasound details. I will try and get before and after pics taken from the same distance and angle, even though I never thought I'd be posting pictures of my penis on the internet. (Especially in its present state.) I now wish I'd taken pics of myself, with rulers and all, before onset, but I used to think that was the kind of thing only crazy people would do. As Vonnegut titled one of his story collections, Welcome to the Monkey House!

[incautious]

ursus. Good Luck. make sure you bring pics with you to the Dr. so that he gets a good idea of where to inject. There are now twice as many Dr's now doing this procedure compared to last year. It is becoming more and more accepted. Be diligent about pumping!

[james1947]

I am sorry to post a non positive result, but 8 weeks after my second session of the PRP injections the results are nothing.
I mean even the improvements I posted after the first session have gone.
I am planning to get the third session in a month.

James

[chandnitare]

James:

Very sorry to your final outcome. Anything to think about the clinic who are doing PRP?
Would you consider not to do VED during third session?


Any one else here with such no improvement?

Best regards,

Chand

[Knight]

Very sorry James.  

[Nordicz]

James,

I'm sorry to hear your outcome wasn't positive. Don't loose faith and keep positive.

Z

[james1947]

No, I am not losing faith, this is the reason I will make the third session of PRP.
It seems to me that PRP, like any other Peyronies treatment it helps some, but not all.
Regarding VED, next time I will not use and will see the results.

James

[UrsusMinor]

I had a nice chat with the doc I'm considering, and he thought the strongest effects of the injections seem to come after a number of months.

But he also said that results vary, and that Peyronie's is a mysterious disease--and that it might actually be more than one disease in the first place. Judging from what I hear around here, I can believe that.

I haven't had this condition very long, but I'm 60 years old, so I'm not expecting miracles.

On the other hand, a miracle would be okay.

[NeoV]

Sorry to hear that James!

Ursus I get the same feeling as well. Peyronie's comes with a bunch of other issues it seems or is a result of them. My impression is that PRP injections are fairly low risk, and after all, we have not heard of a case of scarring after a shot yet. Though perhaps even that would be inevitable eventually.

Still, it seems low risk and effective for some, and this is why I haven't been to critical of it so far. Compared to surgery or Xiaflex, PRP is cheap, and moreover safe.

More than anything I'm just curious how your experience with it (and others) from here on out will go! I do plan on getting it next time I'm in the states.

[George999]

I agree with Neo and other posters here as to Peyronie's.  I consider it more of a syndrome than a disease.  It is a result of healing dysfunction in the tissues and there are probably numerous factors that provoke it which can vary by individual.  Nevertheless, Priapus shot will have to be judged more on its long term results than short term.  Until some of you who have undergone treatment have a few years under your belt, the benefits, or lack of, are really not going to be clear.  But we all owe a big debt of gratitude to those of you who are willing to pay for this treatment and give it a try.  Hopefully you will ALL let us know how you are doing as time goes on and not just drop out of sight if things are disappointing.  All information is extremely valuable, even negative information.

[emasculated]

@George999: I have read some of your posts. Apparently, you suffer from this now for 13 years? You have amassed almost 3000 posts. I'm just wondering whether you still think there is going to be any progress in your lifetime and where you get the motivation from to hope for decades and decades. (Sorry for picking you out like this)

[UrsusMinor]

Hopefully you will ALL let us know how you are doing as time goes on and not just drop out of sight if things are disappointing.  All information is extremely valuable, even negative information.

Right on!

[George999]

@George999: I have read some of your posts. Apparently, you suffer from this now for 13 years? You have amassed almost 3000 posts. I'm just wondering whether you still think there is going to be any progress in your lifetime and where you get the motivation from to hope for decades and decades. (Sorry for picking you out like this)

No problem!  You have to understand that back when I started on this adventure, there was nothing really.  Pentox was being touted, but was still largely inaccessible.  The stuff the docs were giving Peyronie's patients back then were no better than sugar pills.  Some guys were finding VED extremely helpful but most docs were still not supportive of it.  Since then we have both Pentox and CoQ10, both were very effective in my case and even more effective combined.  Additionally, during that time a lot of docs have embraced VED and traction, and the community that makes up this forum had a lot to do with that.  My condition pretty much stabilized long ago.  A couple of flare ups were easily and instantly controlled by Pentox.  So I am very thankful actually that after literally centuries of a "you just have to live with it" attitude from the doctors, we now within the last few years have multiple resources available.  When you really look back on my story as I perceive it, you will understand why I am more hopeful now than ever.  The guys on this forum are trying all sorts of things and the researchers are working on things like Xiaflex and we are learning new things every day.  Most things, of course, won't work out.  But every now and then, something will, and the cumulative effect of all of this will be to continually increase our quality of life over time.  If you think things are depressing now, you can't imagine how much more depressing they were a few years back.  I am just so happy with the outlook today, medically.  Other areas, not so much, but in the area of medicine we are on the cusp of huge breakthroughs across the board.  Of that I have no doubt.  So why sulk in a pity party?  You have to have patience, learn everything you can and apply as much of it as you can.  Not only in terms of treatments, but also in terms of diet and lifestyle.  It can change your life and make it so much richer.  It can also save you from far worse things than Peyronie's coming your way in the future.  I am thankful in that regard for Peyronie's.  Who knows what it might have saved me from?  I much prefer it to end stage heart disease, liver disease, kidney disease, cancer, and so many other things that are so much more devastating than Peyronie's.  Peyronie's only takes you down if you let it conquer you.  Once your life is no longer centered around yourself, the burden becomes a whole lot lighter.

[james1947]

Thank you for the good advice George:

Peyronie's only takes you down if you let it conquer you.  Once your life is no longer centered around yourself, the burden becomes a whole lot lighter.

James

[Chef Chris]

James I am sorry to here that your not having any progress I hope it will turn around for you soon  

[james1947]

Will see after the third shots.
If also no significant improvements, the only thing will be an implant.

James  

[IhatePD]

Hello all I just want to give an update.  I got the PRP shot on June 18th and did my VED for the first week. I was supposed to go away camping on June 25th but that didn't happen. as I mentioned in my last post I had an issue with a bleeding prostate which happened 3 years earlier also.

Well, I went to my urologist on the 24th and then straight to the emergency room and in the hospital for 8 days.  I had a ruptured blood vessel in my prostate that they couldn't get to stop bleeding. The last 16 days of my life have been a living hell that's hard to explain. I've had 6 different catheters, a sysoscopy cauterization of the prostate, emergency room visit last night to irrigate and change a blocked catheter making it three times I almost ruptured my bladder. The ultrasound for bladder retention only measures up to 1,000 cc's and I emptied over 1,400 cc's in just five minutes after they out in the new catheter.  The pain was unbelievable.

In the last 16 days the amount of pain and abuse I've taken on my penis, urethra, prostate and bladder is beyond what I can explain. I've had a catheter inside me the whole time except for one day, this passed Monday when we took it out had to put it back in yesterday after I couldn't pass urine, only to have that catheter block sending me to the emergency room last night.  I have to keep this catheter in me until at least this coming Monday.

Ultimately, I will probably have to have prostate surgery, Transurethral Resection of the Prostate (TURP). I am not happy about that either.

I can't give an update on my PRP because I haven't been able to have an erection during this time and of course no traction or VED. I've got to say as bad as Peyronies Disease is, when you can't urinate and you're about to explode your bladder, Peyronies Disease doesn't even enter the picture.

I have no idea what is happening since my PRP shot but I will let you know as soon as I do. I've got to say that I am very concerned about all the objects that have been jammed in and out of my penis. I don't want to think about the possibility of more damage leading to more Peyronies Disease, but now I can't help but think about it.

[nemo]

My god man, I'm so sorry about the hell you're going through.  Truly sounds horrible and I know the Peyronie's drifts in and out of your consciousness in the midst of all this.  All I can say is we're pulling for you and wish you the best.  Hang in there and take care of each challenge in turn ... the prostate/bladder is issue is obviously No.1 ... deal with Peyronie's when things settle down.  Peyronie's can be your "long game" ... this other stuff is hopefully a short-term challenge.  

Best,
Nemo

[james1947]

IhatePD

Sorry to read what you are going true.
Wish you all the best, my prayers with you for successful outcome from everything you will do.

James

[dioporcolorisolvo]

I did Priapus Shot in 30 April 2014.
After 2 months and half, i've seen no changes in dimensions.
I didn't repeat the treatment.

An italian urologist, after an ultrasound of penis, said me that my disease is stabilised, the situation in his opinion is not grave, but in these years i've lost the elastic fibers and this has provoked the loss of girth.
This situation very likely is not reversible.

In other words, i've not more a fibrous but tissue is not elastic as before.

The life is beatiful....

[james1947]

Sorry Dio the PRP didn't helped you.
It didn't helped me either, but I will make a third treatment soon.

James

[yyy]

Hi dioporco (ahah bel nick )

Did you have a fibrosis before your prp injection? If so, Did it dissolve? This would be a great result

[RoyHobbs]

James-

I thought you saw some improvement in your ED?

Also if it hasn't worked why go for a 3rd round? Just curious.

[james1947]

Roy

I had some ED improvements after the first shots, but now all are gone, back to phase 1.
The reason I want to try the third time is to give it one more chance. I am taking in consideration that the poor results are maybe because of my not too healthy life stile.
I am paying $ 180 for one session of shots, so is not too much to give it a last chance.

James

[RoyHobbs]

Yes, 180 is not bad at all. So why not!

I wish you luck.

[Bjbroken]

180.00 seems very reasonable, what are guys paying in the US?

[UrsusMinor]

Costs used to be about $1,800-2,000 in the US, but it seems to be falling. I'm hearing $1,600 and even $1,400, and it wouldn't surprise me if it is available cheaper from some folks.

Still, it's so much cheaper in Indonesia that if you could get a discounted fare it might be about the same to get the shot in the US, or get it in Indonesia and have a vacation at the same time!

[james1947]

The first session was much more expensive at $ 200
Second I got 10% discount so became more cheap at $ 180.
Regarding holiday, when you are living here you feel always in holiday, even while you are working and it is dangerous because you get lazy

James

[yyy]

I have some questions for you all.

How Many Cc of blood do they take and how Many cc do they inject?

Any reliable doctor here in Europe? Thank you

[james1947]

In my case, because my platelets counts are around 1,000,000 the quantities were different that usual.
Extracted 30 ml, injected 9 ml.
Usually should be 60 ml extracted for 10 ml PRP.

James

[fredjones]

Getting my shot early august..still unsure about doing it.  some fear, some uncertainty.   haven't seen any updates recently from others. you other guys that have had it, can you give some updates, positive or negative?

[incautious]

fred, nothing new to report in my case. Every thing seems to have leveled off.  My plaque is gone, and every thing else is the same as back at the 16 week mark. For me it was money well spent.

[NeoV]

I also plan to go to Totalmale to see dr. Sachman in San Jose this September and am making plans now. Since my scars seem soft ( if they are scars ) I'm quite hopeful. Any more improvement at this point and I'll be without a doubt in pre-peyronies condition.

Regardless of whether the prp works or the benefits are from the fluid injected expanding the tissue, I'm going to try it. I'll take plenty if pictures showing my deformity before hand, flaccid, partially erect, and max, so we can all have a good look. I already have plenty

By the way, Mentos where'd you go?

[UrsusMinor]

Fred, if you don't mind my asking, who are you thinking about going to for the shots? I think it would be good if we could track who we visit. Most of the members who have done the shots have said who they saw--although I haven't been able to locate the doctors seen by MikeHawk and Mentos.

I'm tentatively scheduled to do the PRP shots next week with Jason Sachman (the same guy Neo is seeing in September). Sachman has already done one of the other guys from this forum. That's  one of the reasons I was comfortable with going to him, even though he's 400 miles from me. (There is another guy 7 miles from my house, but as far as I can tell he hasn't treated anyone from this forum and apparently hasn't used the shot for Peyronie's. So I'd rather jump on a plane and use somebody who has at least one endorsement from someone I trust.)

Sachman has done a lot of Priapus shots. Only three of those have been for Peyronie's, I believe, but in the world of Priapus therapy for Peyronie's that makes him pretty experienced. (After I and Neo have both seen him, he may have caught up with Varano, who seems to have treated more PDS forum members than anyone.)

I admit that, like FredJones, I'm a little nervous. I've been dithering about it. My first symptoms emerged in February of this year, so nothing is really stabilized yet, and part of me wants to think oral meds and VED could completely reverse things.

On the other hand, maybe the shots will do more for me if I do them sooner rather than later.

Most of the people on this forum who have done the shots were happy with the results; a few had no change, or had improvements that then disappeared. But so far no one seems to have reported a problem from it. So it seems like a pretty minor commitment compared to implants, or surgery, or even Xiaflex.


I'm not expecting miracles--though I'd be happy to have one!

--------------------------------------

And, yes, I have taken a BEFORE photo from a standardized, reproducible height and distance, with a bone-pressed ruler for reference. I may not have a whole gallery, like Neo, but he's living in Japan, where they take pictures of everything.

[fredjones]

I'm seeing Jason in San Jose also....in a couple of weeks....i'll let all know how things go.   looking more for increased sensation and trying to get off cialis (ED)...good luck to all.

[fredjones]

Im also looking for recommendations for a VED.  the dr. is giving an encore vet-u with the P shot.  he said that i could get 80 dollars back if i buy another one. i just don't know anything out there effectiveness wise nor quality wise or ease of use.   your input will be much appreciated.

[NeoV]

Hey fredjones, I haven't heard of that VED but my opinion is that any VED works, even a cheap sex toy one. The factors to watch out for are is it manual or battery operated? And how big or long is the tube? I recommend a manual pump for safety and convenience, but you may want to ask around.

VED is effective, and I highly recommend you research our VED forum. I consider it a near miracle device for penile health and reduction of deformity, but of course as with all things we have against this disease, some people are not helped by them (it would seem). Check out the forum section and message Old Man with any questions, he's the most experienced with VED here.

[fredjones]

thanks again for all your help.  Old Man has contacted me and has also helped a lot  

[nemo]

Here's an article published today in the Washington Post on PRP - I can't link to it since it's a pay site, but am attaching the text pasted here. - Nemo


Jury still out on plasma therapy

CHRISTIE ASCHWANDEN
THE WASHINGTON POST

   They might as well call it magic. One clinic's website dubs platelet-rich plasma (PRP) therapy "revolutionary." Other purveyors call it a "breakthrough" and "a paradigm shift."
   The treatment involves injecting concentrated platelets, taken from the patient's blood, into the site of injury to speed recovery. Stories of PRP's use by high-profile athletes have turned it into a lucrative business.
   Tennis star Maria Sharapova turned to it for a shoulder injury, and Hines Ward used it to overcome a knee injury in time to help the Pittsburgh Steelers win the 2009 Super Bowl. The PRP market was valued at $45 million in 2009, and it is expected to grow to $126 million by 2016.
   Yet the question remains: Does it work? The evidence remains questionable.
   In April, the Cochrane Collaborative, a group of independent medical experts, examined 19 trials of PRP for eight conditions and concluded that the evidence is insufficient to recommend PRP for musculoskeletal soft-tissue injuries.
   A PRP treatment begins with a blood draw from the patient. Next, the blood is spun to separate platelets from the other blood cells. The process creates a solution of concentrated platelets and growth factors that is injected into the injured area to promote healing.
   "We don't know if it helps people," says Frederick Azar, president of the American Academy of Orthopaedic Surgeons. "The clinical evidence is controversial." Some studies show a benefit, some don't, he says.
   A randomized, double-blind study published last year found that PRP outperformed a placebo for osteoarthritis of the knee. A review published last year noted increasing numbers of clinical studies of PRP, turning up positive and negative evidence for its effectiveness, but concluded that there is still little evidence that PRP works better than a placebo in most cases. Similarly, a review published in June concluded that there is "strong evidence" that PRP is not effective for treating tennis elbow. A randomized, double-blind trial published as a letter in the New England Journal of Medicine in June concluded that PRP was no better than a placebo for hamstring strain.
   The Cochrane review found that most studies are small and not definitive. The wide variety of methods used to deliver PRP and the absence of a standard methodology may explain why studies have reached such different results, Azar says: They're comparing different ways of delivering the treatment.
   MANY USES
   Despite the lack of standardization and definitive evidence, PRP is used to treat a wide range of maladies, including chronic tendon injuries, acute muscle and ligament injuries, osteoarthritis of the knee, and to speed recovery from surgery and fractures.
   If PRP hasn't been validated in studies, why is it in such widespread use? Because even without conclusive evidence, those who provide PRP believe in it.
   "We don't have enough information to show that it works, but we believe it has great potential to work," Azar says. "There's little downside or risk that would prohibit us from offering this."
   Some patients might point to the cost — which can range from $500 to $1,200 for a single treatment — as a downside. Most insurance companies won't pay, since the treatment is experimental.
   But that doesn't stop doctors and clinics from marketing PRP to patients, some of whom are desperate to return to their previous activities. "This is one of those things that falls between the cracks," says Karen Maschke, a bioethics scholar at the Hastings Center in Garrison, N.Y., because PRP doesn't fall under the Food and Drug Administration's jurisdiction. As a result, patients have to rely on their physician to "do no harm," she says.
   "Orthopedic medicine has a long history of pushing procedures and devices that don't fall under FDA regulation," Maschke says. "They're engaging in entrepreneurial medicine." Procedures such as PRP can generate a lot of income for doctors and clinics, and if the practitioners providing the treatment really believe in it, they may think they have a right to offer it, even if there's not strong evidence to support it, Maschke says.
   DOING NO HARM
   When asked whether it's ethical to market an unvalidated treatment, Azar replied, "I'm comfortable with it. My son has had a couple of these injections, and I'm comfortable because the downside from a patient-safety standpoint is minimal."
   He doesn't see the cost as a problem. "If the patient is fully informed and they want to do it and they want to pay for it, I think it is ethical," Azar says.
   "Usually, I won't offer it upfront," says Bryan Murtaugh, a sports medicine physician at MedStar National Rehabilitation Network in Washington. He calls PRP "part of the spectrum of treatment options" and says he normally recommends other approaches first, such as physical therapy, medication, activity modification, bracing or even steroid injections.
   If those don't work, "I always tell patients that it's a treatment option," Murtaugh says. "There is a part of it that's still experimental."
   Patients may not get this cautious message by perusing MedStar's website, which describes PRP as a "paradigm shift" and refers to "convincing evidence of its efficacy" for certain problems.
   Murtaugh readily acknowledges that "studies have shown mixed results." He can't say for sure how effective PRP is. "It's really hard to quantify anecdotally," he says, and since he doesn't systematically track its outcomes in his patients, he can make only ballpark estimates of what proportion of his patients benefit from the procedure. "I'd say at least two-thirds to 75 percent might see a partial response. Some people get a complete response, and a percentage don't get any improvement," he says. "I wouldn't say it's perfect science."

[UrsusMinor]

Thanks, Nemo.

"I'd say at least two-thirds to 75 percent might see a partial response. Some people get a complete response, and a percentage don't get any improvement," he says. "I wouldn't say it's perfect science."

I'd settle for that!

Here is the Cochrane review mentioned. http://summaries.cochrane.org/CD010071/MUSKINJ_platelet-rich-therapies-for-musculoskeletal-soft-tissue-injuries .

The authors of both the Cochrane review and of this Washington Post article are way behind the curve (oops--no pun intended, really, this is an edit!), since they are lumping many different kinds of treatments together. As the NY Times article we have previously discussed put it:

But, he said, there are fundamental differences between overuse injuries, such as tendinopathies, and acute wounds, like those created in animal experiments. In acute injuries, the body initiates a robust healing response, which, Dr. de Vos said, P.R.P. may intensify. But in overuse injuries, the healing process is often blunted, and P.R.P. seems unable to augment it much.

Where does Peyronie's fit into those categories? Hard to say.

Just for the record, here's a summary of the forum results, with "1" meaning improvements; "0" meaning no change, temporary improvements that then disappeared, or nothing reported; and "-1" for a net negative change. I apologize to anyone who feels I have mischaracterized their results; they weren't reported in a standard way, and many people did not mention various factors. (ED in particular was often not mentioned--possibly because it wasn't a problem for the person reporting.)


                       Curve      Size       ED
MikeHawk                  1         1         1
loyalty*                  0         1         0
Incautious                1         1         1
Mentos                    1         1         0
MattFoley                 0         1         0
James**                   0         0         0
ChefChris                 1         0         0
dioporcolorisolvo         1         0         0
IhatePD                   1         0         0

TOTAL                     9         5         2
% improved               66%       56%       22%              

*Not Priapus shot, but treatment included PRP
**Saw initial improvements, but they were temporary.
In this regard, a number of Priapus shot practitioners
are reporting good results for ED--but the shots need
to be done again every so often to maintain the effect.


Now, this would never qualify as a clinical study. The only real commonality in the group is some form of Peyronie's. They are different ages, have had the conditions for different numbers of years; some may still be acute, while others may have longstanding plaque that has been calcified. Improvements are all self-reported rather than measured by thrid parties (although this is often true for some factors in clinical studies, too--for example, pain, or erectile function). It is certainly not double-blind--although there are no double-blind studies to back up many common medical procedures. (There are no double-blind studies of heart bypass surgery, for example. There aren't even any single-blind studies.)

One thing that I do like, however, is that there are no "-1" entries in the list. With almost everything else I have seen reported on in this forum, including Pentox, someone has reported ending up worse off. (Possibly just because of disease progression.) So far, no worsening reported with PRP.

Now, it could be that the positives we see reported here are simply the placebo effect at work. (If a placebo can give me inprovement in my condition, bring it on!). It could be that the improvements are all wishful thinking...though that seems improbable to me. They could be spontaneous improvements.

Or it could be that the people reporting major improvements are young, and I'm out of luck. Or their Peyronie's could still be recent and acute, in which case I might be lucky.

Who knows? In any case, based on our fragmentary data, it looks to me as if the reward-to-risk ratio is very favorable.

I'm scheduled for Dr. Sachman this Thursday.