Accolate (zafirlukast)

[MikeSmith0]

Could this be the next pentox?  It's for asthma...but also stops fibrosis in breast implants.  I mentioned it years ago - I think - but I never saw this study.  I took it myself w/ no results (other than a headache) but I had no results from pentox either.

"The collagen fibers and fibroblast layer were reduced in the zafirlukast-treated group compared to the controls. Our study confirms the effectiveness of this compound in preventing fibrosis and putatively also in reducing the extent of collagen reaction when a capsule has been formed."

PayPerView: Reduction of Capsular Thickness around Silicone Breast Implants by Zafirlukast in Rats - Karger Publishers

Edit:  Oh - i should have scrolled down...Looks like James brought this up a year ago...and I brought it up 3 years ago!
ORAL TREATMENTS – Questions and Suggestions - Peyronies Society Forums

Interesting to hear what you guys experienced though.

[james1947]

I don't know if it is the next Pentox because was done in rats.
I would like to have replacement for Pentox as I had very big benefits from it but I can't take it anymore because while on Pentox I have flue every two months.

James  

[MikeSmith0]

Yeah - James, Pentox hurts my stomach and makes me have a hard time sleeping - especially on 3 a day.  It takes a while to really build up and notice the sleep effects - and then it takes a while for them to stop.

Accolate and Singulair both have side effects involving liver function, though - sometimes severe.  I was reading a bit more today.  I forgot I took accolate already (I took everything!) - it did nothing for Peyronies Disease for the few months I took it.  It gave me serious headaches though.  

[skunkworks]

"In zafirlukast-treated patients, we observed a reduction in mammary compliance of 7.69 percent after 1 month, 16.78 percent after 3 months and 24.01 percent after 6 months"

Might have been worthwhile to stick out 6 months (if no liver issues present).  

[yyy]

any updates?