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Author Topic: PENTOX effect on Peyronie’s - Forum Experience  (Read 45509 times)

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james1947

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PENTOX effect on Peyronie’s - Forum Experience
« on: March 27, 2012, 10:07:20 AM »

I am attaching a file that is a collection of the forum statements regarding Pentox, just from members personal experience.
I had given points for each post and the average come out 62.6% of satisfaction.
Other people may give other points for the different sentenses.
I have attached the Word file so everyone can download and change the points I have give for his own conclusion

James
 
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

Norm

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #1 on: September 21, 2012, 11:04:54 AM »

This is an outstanding piece of work, sir! I wish everything we discuss here could be compiled so concisely. Thank you for the effort.
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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #2 on: May 10, 2013, 09:05:54 AM »

This forum is a lifesaver.... thank you so much to the men who started this!
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james1947

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #3 on: December 22, 2014, 08:10:21 PM »

PDnotFORme

I can propose you to take in addition to Dr. Levine document other Pentox supporting documents from the library, like the Iranian research and tell him also about the very positive results that forum members had with Pentox.
You can also print out the small forum "research" I made, but it was last updated at March 27, 2012.

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

PDnotFORme

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #4 on: February 03, 2015, 09:46:57 AM »

James (and anyone else that comes along)

3 weeks ago, I was able to find a doctor who was familiar with the use of Pentox (400mg 3x D) + L-Arnginine (1000 mg 2x D) + 5mg of daily Cialis. After 3 weeks, the pain has lessened some and girth measurements have remained the same in the area of concern (bottleneck near base), whereas they were getting worse previously. Hopefully this trend continues; I will continue to post updated when possible, as my script is for 6 months.

PDNFM
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PDnotFORme

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #5 on: February 03, 2015, 10:14:12 AM »

Nemo - Thanks! It was a HUGE sigh of relief to find someone that was, and I quote, "familiar with what Levine and Lue do for their patients".

I will share my full story, in hopes that it will help anyone else that is fighting:

I am 26, was a college athlete, 6' tall, 175 lbs (very healthy condition otherwise). I first noticed pain and a narrowing (bottleneck) deformity in October 2014 (5.75 in at base vs 6.25 inches girth around the rest). Length has remained the same since onset, and I do not have curvature. It took 5 urologist visits in 3 months to finally find a doctor who was knowledgeable, and was diagnosed with Peyronie's on January 8, 2015. I live in Indiana, and found a knowledgeable doctor in Cincinnati, OH. I have been on Pentox (400mg 3x D), L-Arginine (1000mg 2x D) and daily Cialis (5 mg). In the past 4 weeks, the pain has begun to subside (2/10 when flaccid, 3-4/10 during intercourse) and intercourse has become possible again. Also, the narrowing has not become any worse in the last 4 weeks. As I previously stated, I will continue to post updates as often as possible.

Has anyone on Pentox/L-Arginine/Cialis (or a similar combination) also tried use of a VED to try to regain girth? I would love to take some positive feedback into my follow up in 3 weeks and possibly add this to my regimen.

Also, I am incredibly thankful for the existence of this forum, as it helped me realize how quickly I should act and was able to receive treatment within 90 days of noticing the issue for the first time (as opposed to a sit and wait approach, as suggested by the first 3 doctors I saw)! Thanks to all!
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james1947

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #6 on: February 03, 2015, 02:26:40 PM »

PDnotFORme

The oral treatment you started shows results as the progression of the disease has halted and the pain reduced as I understand from your post. Happy for you, it is a good sign.
Regarding VED, I am a big fun of it as it helped me and helps others. Be very careful while using it not to over-pump and cause damage.
Please give us the name of the doctor and his location so other forum members will benefit also having an updated doctor.

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

PDnotFORme

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #7 on: March 02, 2015, 09:44:21 AM »

To all: just an update.

I am 60 days into 400 mg of Pentox, 3x daily + 1000mg L-Arginine 2x daily, and 1x daily 5mg Cialis. I also take 400mg Vit E 1x daily.

I had my first follow-up appointment last week - my doctor said not much had changed.. which at this point I will take as a positive sign.

My measurements in length and girth have not changed in the last 60 days, which I will also take as a positive; I am hoping that the progression of the problem is slowing.

In regards to pain, I have not had much of a change since onset. In flaccid state, the pain comes as goes, and it usually in the form of a tingling/burning sensation in the affected area. During intercourse, the pain ranges from a 1-5/10, and sometimes requires stopping. Have also noticed a severe ache after climax, which I am assuming is due to Peyronies Disease (this pain usually subsides within an hour).

I am still hopeful in beating Peyronies Disease, and am continuing to seek out additional opinions (see multiple doctors), considering my younger age. I have not yet had an ultrasound or MRI, and am pushing to have one ASAP with my doctors. More updates to come.

Does anyone have any insight as to how long it took for pain to go away while on a similar regimen? Any suggestions?

Thanks,
PDNFM
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james1947

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #8 on: March 02, 2015, 09:59:56 AM »

PDnotFORme

I think that no Peyronies progression with your treatment is a good news.
Anyhow, 60 days on this treatment is not enough to see the Peyronies symptoms reversing. This kind of treatment  is a marathon, not a sprint.
Wish you starting to see reverse of the symptoms, keep us updated.

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

xman1740

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #9 on: March 04, 2015, 10:46:01 PM »

Hey PDnotFORme.  Our stories sound very similar.  I am 35 and in very good shape and am a healthy eater.  I have always had a bit of a curve downward but it was never painful until a few months ago.  Now I have hourglass shape at the base.  It started in late Dec. 2014 during a sexual experience.  About a week after I started experiencing slight pain when flaccid but pretty painful when rock hard.  Especially if I have an erection while standing.   I went to 3 urologists until the last one prescribed me 400 mg of Pentox, 3x daily + 1000mg L-Arginine 2x daily, and 400mg Vit E 1x daily.  He said Cialis was optional and gave me a script but I don't use it.  That was a month ago.  The pain feels like its slowly subsiding or getting better.  No pain flaccid.  Still pain when hard but only if I'm "rock" hard, which is a bit difficult to achieve.  Anyway just thought I'd share.  Your story gives me some hope.  I go back in to see the doc in 30 days.  To me its sounding like this will hopefully subside or go away in 6 months to a year from what Im reading on this forum. 
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james1947

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #10 on: March 04, 2015, 11:20:36 PM »

xman1740

Adding low dose Cialis to your treatment (2.5 mg if you don't have Erectile Dysfunction, 5 mg if you have) will help together with the Pentox to arrest the disease and reverse the symptoms.

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

norwegian27

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #11 on: March 06, 2015, 12:19:17 PM »

Hi guys. I found a information site about q10 that says "Both vitamin K and Q -10 counteracts the effect of blood-thinning medications , and concomitant use is therefore believed to increase the risk of blood clots" (google translate from norwegian)
 
since pentox/trental is a blood thinning medication, and I've seen that a lot of the forum members use both pentox and q10, I thought that I should share this.

I am currently only using trental 300mg 2 times a day, and some vitamin E. I know that vitamin E is'nt going to help me, but since I bought a package before I found out I might as well just finish it. I was searching online to find somewhere to order q10 in norway, and that's when I found the information that you should not mix it with blood thinning medicine.
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norwegian27

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #12 on: March 07, 2015, 07:45:19 AM »

Sure.

Q-10 | Faktaark |  NIFAB.no

This is a norwegian website, but if you use google chrome it could translate everything for you!
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james1947

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #13 on: March 07, 2015, 08:12:57 AM »

Thanks for the link Norwegian.
I don't want to argue with the article, but no any research is stated from where the information is. Maybe the problem is google translate. From the link:
Quote
Interactions with medications:
Blood thinners (warfarin) High Possible.
Both vitamin K and Q-10 counteracts the effect of blood-thinning medications, and concomitant use is therefore believed to increase the risk of blood clots.
The first sentence mentions Warfarin only, not mentioning other blood thinners.
The second sentence mentioning vitamin K and CoQ10. Is vitamin K mentioned because it effects blood thinners if taken with CoQ10? If not, I don't understand why is vitamin K mentioned in an article about CoQ10.

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

grotesquegnome

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #14 on: March 11, 2015, 11:49:32 PM »

James,
Any update on whether to mix q10 with pentox?
Also do you know if the interaction btwn IBprofen and pentox will be harmful?

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james1947

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #15 on: March 12, 2015, 06:10:40 AM »

grotesquegnome

The only thing I found about interaction is:
Quote
Pentoxifylline reduces the breakdown of theophylline (Theo-Dur, Respbid, Slo-Bid, Theo-24, Theolair, Uniphyl, Slo-Phyllin) in the liver, increasing blood levels and side effects of theophylline. Combining pentoxifylline with warfarin (Coumadin) may increase the risk of bleeding. The mechanism for this interaction is unknown.
Nothing about Petox and CoQ10

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

grotesquegnome

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #16 on: March 12, 2015, 09:30:11 PM »

james
On wikipedia it says coQ10 only interacts with the blood thinner Coumadin, which is a relatively strong blood thinner, but it does this because both coQ10/Vit K and coumadin use the same mechanism, so I'm thinking maybe pentox uses a different mech than coumadin.

Also, where can I buy colchicine? I read a bunch of good studies about the mixture of that with Vit E

Thanks.. also,are you living in romania? I grew up in Bucharest
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Old Man

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #17 on: March 13, 2015, 09:56:24 AM »

grotesquegnome:

Before you purchase the colchicine, check out the posts here on the main forum. The price has really risen since the original form was approved by the FDA. Also, there seems to be very little, if any, assistance with treating Peyronies Disease.

I took it way back in the 1950s when I first contracted Peyronies Disease. Took bottles of it, very cheap then, but it did absolutely nothing toward helping rid my Peyronies Disease symptoms.

It did, however, help an early battle with arithritis. So, do a search in the forum threads/topics and catch up on the posts there.

Old Man
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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #18 on: May 30, 2015, 03:21:30 PM »

I have a question regarding the class of the Pentox:

Is it an actual blood thinning agent (like Coumadin or Warfarin) or does it just allow the blood to flow more freely because it is breaking up the plaque?

If it IS an actual blood thinner is it treated like Coumadin or Warfarin in that you must be carful to not cut or bruise yourself or that you must stop it 7 days prior to a surgery etc....
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Jonbinspain

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #19 on: May 30, 2015, 04:34:38 PM »

Stabler;

A quick answer is that Pentox reduces the viscosity of blood. So yes, it does thin the blood.
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james1947

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #20 on: May 30, 2015, 06:39:27 PM »

Pentox is not exactly a blood thinner like Coumadin, Warfarin, Aspirin. Some effects the same.
The way Pentox is working is making the red blood cells flexible so they can enter the thinnest blood vessels.
Read blood cells supply the oxygen to everywhere in our body so the oxygen reaches the extremities much easier, including our penis.
It may reduce the white cells count also, so yes, as Jonbinspain wrote, reducing viscosity also.

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #21 on: May 30, 2015, 08:25:28 PM »

Thank you James,

That was my concern, that it would carry the same kind of risks as the Coumadin or Warfarin.
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james1947

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #22 on: May 30, 2015, 10:23:11 PM »

Pentox have also risks.
It weakens the immune system and may lower drastically the white blood cells counts.
I had to stop after 18 months because sever flue every 6 weeks, but it didn't affect my white blood cells.
In addition, some suffer from very bad side effects.
Some have no any downside, they are the happy ones.

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #23 on: May 31, 2015, 09:33:32 AM »

I will continue my research on the Pentox of course my initial scare was the blood thinning. It is of course something that we will want to try but I want to make sure that we have all the information.
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newguy15

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #24 on: October 19, 2015, 10:14:59 PM »

I stopped taking pentox last Thursday.  I took it for a little more than two week but it just increased my pain and discomfort.  Its been a week since I stopped taking the medication and I noticed the pain has subsided.  I'm not sure what to make of all of this except that maybe I don't have peyronies disease but something else, maybe more of a mechanical injury.  There is definitely some dents and slight bending of the shaft to the left and I can tell that the left side of my penis doesn't extend equally with the right.  I'm going to have to go back to a urologist and explain this to him.  The only good thing that came from pentox was an increase in blood flow in my erections and my ejaculations.  My shaft definitely felt harder than I've felt it in a while (even before I hurt myself).  Anyway this kind of sucks, I was really hoping to see some improvement with this medication.
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Jonbinspain

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #25 on: January 03, 2016, 12:40:09 PM »

I had calcified plaque. I took Pentox continuously for two years. It did nothing to reduce calcification, as the scan I had done just before my recent surgery showed.

I agree that there is anecdotal evidence of plaque softening, but for me it didn't work. For what it's worth, Dr Kuehhas believes that in the active phase it can be of use, but once you are past that, it will be of little use.
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whoops!

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #26 on: February 20, 2016, 02:09:11 PM »

I have been on Pentox (400mg 3x a day) for about 3 weeks with no side effects.

So far I can report that my pain has disappeared. This medication is just such a godsend for that reason alone. The consistent pain is what was making my life miserable. Yes, the deformity isn't great either, but I can still have sex.

I've also noticed a slight reduction in my rightward curvature. Additionally, my plaques feel a bit softer.
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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #27 on: February 20, 2016, 05:10:52 PM »

Thanks James! I have been wanting to try VED, so perhaps now is the time to start slowly.
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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #28 on: April 28, 2016, 04:51:12 PM »

I am about 2.5 months into my Pentox treatment (I started around 5 months after onset of symptoms) and I am very pleased with how it is going. See below for a quick run down of my experience:

- No side effects
- No new plaques have developed
- My first plaque, which one uro said was partially calcified, that was creating a rightward curvature has decreased in size by > 50%. My dick no longer curves all the way to the right. However, because there is a plaque on the left side of the penis, it now curves to the left. Hah. Also, indentation has substantially has substantially decreased.
- The plaque on my left side of my penis is beginning to shrink and has softened considerably. The indentation is beginning to fill in.
- My pain is gone
- My third plaque has undergone no change. However, it developed just before I began Pentox, so I expect it will take longer to see results with it.

I recognize that I am young and healthy, so my healing may not be completely related to the Pentox. However, so far so good. My doctor plans to have me on it for about 8 months, though I imagine I will take it longer if I keep healing.
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Swimgert

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #29 on: June 20, 2018, 09:28:31 AM »

I have been using Pentox now for a  month. My curvature seems to have lessened during this time, but I know this is a long process and will continue using Pentox for several months to see if the curvature is really reducing. I have noticed that my erections just don't seem to be as hard. Has anyone else on this forum experienced slightly weaker erections? This has made sex with my wife a little more difficult and only adds to my stress regarding this whole situation.  Is this a possible side effect? I will see my urologist in August for my first checkup after starting Pentox.
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Dennis
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Peyronies Disease started in October 2017
Use Pentoxifylline - headaches and increased Erectile Dysfunction
Daily stretching and molding exercises
Use castor oil, vit e, and scare tissue oil - topical

Steering to the left

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #30 on: July 14, 2018, 05:23:44 AM »

Are these meds / supplements safe to take with blood thinners ? (Coumadin /Warfarin) just curious if you might know right off the top of your head. 

Thanks
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Jason
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Not here to complain about my conditions but to LEARN and HELP when i can ! !

james1947

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #31 on: July 14, 2018, 06:02:06 AM »

I can say from experience and logic's that Pentox don't interfere with blood thinners. (corrected, wrote by mistake Pentox don't interfere with Pentox)
While on Pentox, continued with 100 mg aspirin every day.
Pentox is not a blood thinner. Pentox makes the red blood cells flexible so they can enter the thinnest blood vessels.
But you may want to ask your GP. 

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

Todaypen

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #32 on: April 08, 2019, 01:35:14 AM »

Hi everyone,
I just started taking Pentox 2 days ago. 
Day 2 - started to feel nauseous.  I think I took the morning and lunch dose to close together.
Day 3 - feeling depressed.  Not sure it is from the Pentox. Or just trying to figure out what to do with Peyronies.  Should I just take Pentox (that is all Dr. Liu gave me). Should I also take Cialis or Viagra? I dont have Erectile Dysfunction, but have read on the forum it might be helpful? Should I take any other oral items? So confusing, and feel lost. 

Anyone have ways to lessen the nausea when on Pentax? Or lower the depression?

Any advice would be appreciated.
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50 years old, 10 degree curve down (at top, underside of shaft), No Erectile Dysfunction, taking Pentox 400x3 times a day.

Just accept, cry, then take courage, chin up, and search, try, fail, try again, and finally succeed (quote from Gabriel)

tonyode

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #33 on: April 09, 2019, 11:10:52 AM »

Todaypen...I have been on Pentox for almost two months now. Along with a bunch of other supplements as well as going through the Xiaflex injections. I have experienced some nausea. But not often or severe. I only take it when I am eating something, which is recommended. Also a bit of diarrhea. Not bad though. Depression? I don't believe that is listed under the possible side affects. Give it some time to adjust to your body. But like anything else, everyone is different. Some experience the side affects, some don't.
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Early 50s, 7 months diagnosed. 55 degree curve, indentation at base to the left.

TonySa

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #34 on: April 09, 2019, 02:57:02 PM »

I’d say always add a physical therapy to pentox (traction &/or VED) for best results (and even a low dose nightly PDE5i
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

james1947

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Re: PENTOX effect on Peyronie’s - Forum Experience
« Reply #35 on: April 10, 2019, 04:05:32 AM »

Todaypen

I was taking Pentox 3*400 mg per day.
First with breakfast, second with lunch, third with dinner. Always with meal!
Last one at dinner at least 3 hours before going to sleep.
Start with one per day until your body will get used to, no side effects.
Continue with 2 per day (breakfast and dinner) until your body will get used to, no side effects.
Continue with 3 per day.
Wandering why your doctor didn't explain you how to take Pentox :( Maybe he didn't care too much about what happening to you.
The low dose Cialis every second day is because researches show that Pentox/Cialis combination works better that Pentox alone.
You don't have Erectile Dysfunction, so take 2.5 mg. Cut the 10 mg in 4 to reduce the price.
As TonySa wrote, add VED or traction to the treatment. Carefully not to damage yourself.
Myself using VED, sometimes using Viagra instead of Cialis if I was running out of stock. Cutting Viagra 50 mg in 3, not easy but can be done.

James

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum
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