ORAL TREATMENTS - GENERAL - Vitamins, Prescriptions , Herbs, Supplements

[phil]

So George, should we take ALC and if so how much?

[George999]

So George, should we take ALC and if so how much?

Phil,  I think that is something only you can decide.  There is SOME evidence that ALC is helpful.  There are a lot of testimonials (including my own) to the same effect, but they are not really worth a whole lot.  About the only thing you can do is to look it over and give it a try and see if it SEEMS to be helpful for you.  Personally, it seemed extremely helpful to me for a long period.  So I took it, about 2-3g of it a day.  Then I seemed to be having a problem with it and stopped it.  It turned out the ALC was not the root of the problem and so now I am taking it again, but only 1g per day.  When I finish my supply on hand I will probably be discontinuing it.  My current focus is on Pentox and Vitamin D, everything else is pretty much additional to that and dispensable.  - George

[Toby]

Hi guys, havent logged on in a while. I have been using the vaccuum pump for a while now, with not much improvement. My question today is about protein powders used in weightlifting and glucosamin chondroitin used for pain in the joints. Has anyone heard how these might affect Peyronies Disease. I thought I read somewhere where protein and amino acid supplements could make peyronies worse. I called my uro and he gave me the ok but I just cant shake this feeling that I read about these products not being good for peyronies. anyone else hear this?  

[Hawk]

There have been some anecdotal reports against glucosamin chondroitin and at least some logic for suspecting them for having a possible negative impact since they are supposed to help generate the type of collagen found in Peyronies Disease. I am a bit skeptical but I am cautious and do not use them.

As far as whey protein is concerned, I only ever heard it suspected by one member.  I have used it off and on in varying doses for decades and never noticed any correlation with Peyronies Disease progression or flare-ups.  Whey protein has many advantages in general health too numerous to mention here.

[George999]

I suspect that something like whey protein might be a problem for some people and not others.  I think that if we start to nitpick all the stuff that *might* be harmful or that somebody thinks is harmful, we will rapidly be left with little in our diets.  So we do have to remember that we are individuals and when we read that a beta blocker caused somebody to have Peyronie's, we need to think twice before we up and quit out beta blocker medication.  If we can successfully transition on to a better med or a better diet, that is a good thing.  But just to drop things that have other beneficial, perhaps even life-savingly beneficial effects is just stupid.  Thats why I sometimes get a little uncomfortable with too much fixation on suspected "causes".  On the other hand, if something is very perceptibly making things worse, by all means, do something about it.  - George

[despise]

George what does ACL do? does it help take down inflammation? would you reccomend me getting it? is it expensive?

[ComeBacKid]

George,

I found this online from the wikipedia in regards to Vitamin D:

"In the absence of vitamin K or with drugs (particularly blood thinners) that interfere with Vitamin K metabolism, Vitamin D can promote soft tissue calcification."

Asssuming one is on a multi vitamin like me with 400 IU or 100% of vitamin D, and I"m on a blood thinner like pentox, isnt that bad, if vitamin D promotes soft tissue calcification?

Comebackid

[Hawk]

I suspect that something like whey protein might be a problem for some people and not others.  

George, I agree that individuals are uh....well individual.  We all respond somewhat differently to foods, drugs, diseases.  My first thoughts about whey protein is that it is protein.  It is just an array of amino acids that form a "complete protein".  The amino acids are those found in other foods like soy, beans and especially meat but without the fat load that meat carries.  It is easier to digest and assimilate.

If you think whey protein could have some direct effect on Peyronies Disease, is that based on a response you have noticed and seemed to pinpoint an association with in yourself or have you heard of some mechanism associated with a component of whey that is not present in other foods?

[George999]

This is why I recommend anyone taking Vitamin D take at least a small amount of Vitamin K daily.  Over the last six months I have been taking large amounts (12,000IU per day) of Vitamin D in order to get my blood levels up where I think they should be.  Along the way, I have been taking 500mcg of K1.  I am now taking 90mcg of K2 per day.  The problem here is that fixing vitamin D levels can reveal (or perhaps cause) a deficiency in vitamin K.  The blood thinner issue is NOT a problem with Pentox, it is ONLY a problem with blood thinners that specifically target vitamin K, like Coumadin.  People on something like coumadin should NOT be taking large amounts of vitamin D.  - George

George,

I found this online from the wikipedia in regards to Vitamin D:

"In the absence of vitamin K or with drugs (particularly blood thinners) that interfere with Vitamin K metabolism, Vitamin D can promote soft tissue calcification."

Asssuming one is on a multi vitamin like me with 400 IU or 100% of vitamin D, and I"m on a blood thinner like pentox, isnt that bad, if vitamin D promotes soft tissue calcification?

Comebackid

[George999]

If you think whey protein could have some direct effect on Peyronies Disease, is that based on a response you have noticed and seemed to pinpoint an association with in yourself or have you heard of some mechanism associated with a component of whey that is not present in other foods?

Hawk, the whole issue surrounding a possible immune system connection with Arginine has caused me to seriously rethink this whole amino acid thing.  It makes it apparent that SOME amino acids, INCLUDING ARGININE, can have a subtle stimulating effect on the immune system.  And that would make them a possible two edged sword when it comes to Peyronies.  Arginine, for example, could be producing obvious benefits, while at the same time promoting not as obvious pro-inflammatory processes.  This could also be the case with horney goat weed since horney goat weed is usually formulated with maca.  Maca contains copious amounts of readily available arginine.  And if arginine can cause subtle changes in the immune system, so can a host of other amino's and even foods, since they are loaded with amino's themselves.  I just ordered a whole container of VasoFlow, but now that is on hold, since it seemed to promote a flare up in my neuropathy symptoms.  If it is doing that to my legs, I wonder what it may also be doing to my penis?  - George

Disclosure:  I AM still using whey protein in moderation.  I guess I'm just hoping that the nutritional benefits outweigh the potential liabilities.  And I guess that is where we all stand.  We each have to weight potential benefits against potential liabilities and make a decision.

[George999]

Here is an article outlining new evidence of a link between vitamin D deficiency and an increase in systemic inflammation levels.

Vitamin D Deficiency Related to Increased Inflammation in Healthy Women, MU Study Finds

Increased concentrations of serum TNF-α, an inflammatory marker, were found in women who had insufficient vitamin D levels. This study is the first to find an inverse relationship between vitamin D levels and concentrations of TNF-α in a healthy, non-diseased population. This may explain the vitamin's role in the prevention and treatment of inflammatory diseases, including heart disease, multiple sclerosis and rheumatoid arthritis.

[newguy]

I do think that especially in certain climates Vitamin D deficiencies are rife. Here in the UK, milk is not typically fortified with Vitamin D and it's only sunny for about 2 months of the year. So, from that perspective I do think that Vitamin D is very useful.

Many, many studies also prove to me at least, that it is a valid addition to a peyronie's regime. I do worry about the increased risk of soft tissue calcification, and don't truly believe that anyone knows for sure how much Vit K to use, or whether it's actually possible to totally remove this concern, but with many studies stating beneficial anti inflamatory qualities, it'd be a mistake not to take Vit D supplements. There's a good argument around "how much is too much?", and I do think that we talk about Vitamin D way too much around here, but with new studies coming out frequently, it's an inevitability. These cancer risk studies are of concern, but I think i've found a balance, so am not shovelling what I deem to be excess amounts of any supplement down my throat.  

[George999]

Just a quick mention of a rather breakthrough method of treating prostate cancer:

http://www.healthday.com/Article.asp?AID=625875

[nemo]

Since I started the whole "rethinking amino acids" thing with my tale of how a dermatologist questioned whether my Arginine supplements might be causing my Vitiligo skin condition by "messing with the immune system" (vitiligo is an auto-immune condition), I should follow up.  

I voiced the dermotologist's concern to my specialist, a behavioral neuroendocrinologist, and he said he felt the amount of Arginine I was taking (2 grams a day) in all likelihood had nothing to do with an auto-immune response like vitiligo.  He rightly pointed out that there's as much or more arginine in a big steak or an egg as I was taking.  

He is also the one who put me on Vit D, 10,000IU a day, as I tested at 32 and he wanted to bring my level up. Recently, I tested again and my level was up to 50, so that's definitely working.  I am taking some K with it (not at his recomendation), but who knows if it's the right amount or not - I guess it's a shot in the dark.  Glad to see my D coming up though.

Nemo

[George999]

Nemo,  I think you are correct that the amount of arginine we would be taking is not likely to tip the scales in terms of an immune response, however I do have some reservations about the VasoFlow formula in this regard in that I wonder if it might not be causing arginine to "back up" systemically to a point where there might be an unhelpful immune response.  So I do think this is potentially a very individual thing where it might benefit one individual while another not so much while another it *might* be potential negative.  In any case, I am not going to take it for a while until things really settle down.  My erections are actually so much better after having my vitamin D levels raised for a while that I really don't need it all the much now anyway.  - George

[Hawk]

I have two brands of whey protein in the house "EAS" (major brand) and "Body Fortress" from Walmart.  They have 630mg and 400 mg of arginine respectively (per serving).  Total protein per serving is about 24 grams.

Out of curiosity I looked up arginine content of foods and found that a steak has 5000-6000 mg or ten times the content of a serving of whey protein.  It is also double what most any of us would take in the form of an arginine supplement like Vasoflow.

http://www.traditionaloven.com/tutorials/l-lysine_rich_foods.html

This raises a few questions like: why not eat a burger instead of taking an arginine supplement and why does it not seem to give the result of arginine supplements?  Next, IF whey can cause any response in a person's Peyronies Disease for the good or bad, it must not be the arginine content because it is modest compared to the content of arginine in many other foods we likely eat every day.

[joecancer]

Does anyone know anything about Whole Oat Powder (avena sativa).  It's in a gnc vitamin pack I got, which also includes 1000 mg l-arginine.  Is this the same things as oats?  Anyone know if it's safe to take?  Apparently it is supposed to improve sexual function, but I'm not exactly sure how.  

[Hawk]

Joe,

There is no evidence that arginine has any negative effect on Peyronies Disease.  In fact the cutting edge specialists with an emphasis in Peyronies Disease prescribe the combination or L-Argine, Viagra, and Pentox.  It is likely to help.  Any individual can have a rare reaction or response to almost anything, but a negative response would NOT be the norm.

[George999]

Just for the record here, I agree pretty much with Hawk on this.  In our discussion of arginine, I think we are pretty much in the realm of splitting hairs.  I think the likelihood of it being helpful is really a quantum higher than the potential for it being harmful.  So UNLESS one has reason to believe it is actually causing them a problem ... like ... I take it, things get worse ... I stop it, things get better ... I start it again, things get worse ... etc.  UNLESS you really KNOW it IS causing you a problem, it is probably beneficial.  And this whole conversation could go far beyond arginine.  Almost everything in our food chain has some remote potential for causing harm.  Such is the danger of carrying nit picking to far.  You can end up starving in fear of every food item on the planet.  So all of this needs some degree of perspective.  If you are having good vigorous nocturnal erections, you can probably do without extra arginine, but if there is some measure of doubt about that, arginine will almost certainly cause you more benefit than harm.  And in many ways, I still am convinced that SANN VasoFlow is just about the best most effective arginine formula out there.  And I've used it for several years now.  - George

[ComeBacKid]

"This is why I recommend anyone taking Vitamin D take at least a small amount of Vitamin K daily.  Over the last six months I have been taking large amounts (12,000IU per day) of Vitamin D in order to get my blood levels up where I think they should be.  Along the way, I have been taking 500mcg of K1.  I am now taking 90mcg of K2 per day.  The problem here is that fixing vitamin D levels can reveal (or perhaps cause) a deficiency in vitamin K.  The blood thinner issue is NOT a problem with Pentox, it is ONLY a problem with blood thinners that specifically target vitamin K, like Coumadin.  People on something like coumadin should NOT be taking large amounts of vitamin D.  - George"



George so your saying if I'm taking a multi vitamin that has the 100% recommended daily value of vitamin D and K then I'm safe?

Comebackid

[newguy]

ComebackKid - George is suggesting that people take much more than 100% daily recommended value in order to get Vitamin D levels up. Of course taking a multi vitamin is useful but I can't see it elevating your vitamin D levels much.  

[ComeBacKid]

Newguy,

I wasn't inferring how much vitamin D I need to take, but how much vitamin K is needed when one takes vitamin D to offset any tissue calcification...

Comebackid

[nemo]

Comeback, check, your multi might have some K in it too.  The bottom line is no one seems to know how much K to take in relation to D ... that question has come up before, the answer is elusive.  

Nemo

[newguy]

Comebackkid - Oh right, refering to the ratio used in multi vitamins and extrapolating based on that? How much vitamin K to take seems to be a bit of a mystery really, so I guess it would pay to take more rather than less to be on the safe side. However, maybe there are side effects that I'm unaware of relating to K. Of course, "eating your greens" won't hurt either

[ComeBacKid]

My multi-vitamin has 33% of the daily vitamin K and 100% of the daily vitamin D.  There is probably a reason they only put in 33%, perhaps you can easily get vitamin K from another food, or you don't need as much of it...

Comebackid

[newguy]

ComebackKid - I don't personally think that the amount of Vitamin K offered in multi vitamins has much to do with their perceived relationship to one vitamin D, or any considerations such as calcification, as this is something that only becomes an issue with large doses so I don't think it would factor ito their reasoning. My multivitamin for instance offers 50% of the RDA of K. I do agree that Vitamin K is easier to get from food though.

What is apparent to be is that Vitamin K is vital when increased doses of Vitamin D are taken, and as such I'm be inclined to ensure that my diet is rich in Vitamin K from supplmements and food. From wikipedia:

Vitamin K is found chiefly in leafy green vegetables such as spinach, swiss chard, and Brassica (e.g. cabbage, kale, cauliflower, broccoli, and brussels sprouts); some fruits such as avocado and kiwifruit are also high in Vitamin K. By way of reference, two tablespoons of parsley contain 153% of the recommended daily amount of vitamin K. Some vegetable oils, notably soybean, contain vitamin K, but at levels that would require relatively large caloric consumption to meet the USDA recommended levels

In addition, eggs and meat contain Vitamin K2, so thankfully there are a great many options for us .

Here's a forum post elsewhere citing a few studies relating to how Vitamin K can help to redcue calcification:

http://www.thisisms.com/ftopict-6545.html

I'd say that the best way forward is to ensure a plentiful supply of Vitamin D within skimping on Vitamin K, as calcifiction is of course the last thing we need. I do think Vitamin D is an important part of the inflammation preven tion puzzle, and as such we need to ensure that we're maximising the benefits, while reducing the drawbacks.

[Iceman]

alexk - can you give us a sneak preview now and elaborate later...please...

[newguy]

alexk - In line with the below comments, can you elaborate a little on your experience with peyronies? The time periods, pain, curve details etc. I checked your post history and couldn't find much relating to this. If we have a positive story on our hands, it'd be nice to know more .

[Hawk]

I list only my personal results, nothing more.  I took 3 grams of ALC a day for months and slept like a baby.  I have never read on any nutrition site that it interfered with sleep.

[Iceman]

im back having a bit of pain - could it be tribulus - does anyone take this and does anyone have any info on this etc

[Hitman]

just thought I post this

Here is a link on LEF's website about testosterone and prostate cancer
http://www.lef.org/magazine/mag2008/dec2008_Destroying-the-Myth-about-Testosterone-Replacement-Prostate-Cancer_01.htm.

The idea that testosterone replacement will make prostate cancer grow is called "the Huggins myth" in two journal articles. LEF's conclusions:

Low blood levels of testosterone do not protect against prostate cancer and, indeed, may increase the risk.

High blood levels of testosterone do not increase the risk of prostate cancer.

Treatment with testosterone does not increase the risk of prostate cancer, even among men who are already at high risk for it.

I also found this rather interesting reference about zinc citrate PMID: 18310092

[ocelot556]

Nice find, Hitman. It seems the medical establishment is really opposed for whatever reason to testosterone treatment, even though it's been documented that a lot of age-related maladies have a direct relation to the decrease in testosterone production in the body as a man ages.

I keep coming back to that endo who believes that androgen replacement is the cure for all penile fibrosis. I'm no scientist, but I think history will prove his conclusions true.

[gerMike]

Update from my side.

I had a hell of pain all the time in my left leg and my left side of the penis. My penis was permanently contracted and shrunken, hard and felt like dead.

The pain suddenly disappeared in the last days. My penis is now fuller all the day (makes me feel a lot better) and I started to wake up with some morning erections. I noticed that my increased intake of VitD (raised from 1000UI to 5000UI daily) had some effect on the pain. Basically I think my VitD levels are depleted because of the constant inflammation thats going on down there. But thats not the only thing I changed.

I started taking Testogel to treat my low testosterone level (240ng/dl), added 2x600mg Ibuprofen for 3 days and reduced it to 1 time Ibuprofen, increased my intake of Full spectrum VitE from 400UI to 800UI daily. I'm not sure what really helped but wanted to inform you about the disappearing pain and fuller penis since that was very stressing all the time.

My current daily intake:
4x Potaba 3g (for years, difficult to say if it had some effect, maybe less curvature)
1x 25mg Testogel
4x 300mg Pentox
2x 400UI VitE (1x before)
1x 5000UI VitD (1000UI before)
1x MK-7 (Vit K2)
1x Ibuprofen 600 (try to reduce to zero from time to time)
2x Incense capsules (against chronic inflammatory conditions)
2x 800mg L-Arginin
Stopped intake of Acetyl-L-Carnitine

I know its a big list and I changed too much but I was stressed about the pain and the penis that I tried some more change at once.

My recommendation for somebody with pain would be a try of Ibuprofen and check if that helps. Keeping inflammation down is most important in my opinion. Chronic inflammation can lead to so many problems and could affect the whole body, your heart, your vessels and what else. I also noticed that the pain subsided a day after I was in a solarium. Beside that, pain can cause serious stress as it was in my case. I stopped the VED treatment because I had the feeling that the VED excercises increase problems for an inflamed penis.

Hope this information helps someone.

[ComeBacKid]

I to had the shrunken hard, feeling and pain shooting down my leg and penis.  I went on pentox and  multi vitamin and the pain went away, and my penis was really full, and much improved erections.  You could probably cut all that crap and bs out and just take pentox.  The problem with taking that many things at once is that you don't know what is really working!
But at least something is doing the trick for you, thats excellent!

Comebackid

[Hitman]

in my case all pain had ceased after VED usage and penis is more pink. however i have a lot of other areas to cover.

[George999]

The use of a SPECIAL form of Vitamin D in the treatment of late stage prostate cancer is in Phase II testing with excellent results being seen thus far.

Vitamin D Analog Safe in Prostate Cancer

The drugmaker said inecalcitol is more potent and less toxic than calcitriol, the natural active metabolite of vitamin D3, and the company called its clinical tolerance in the study so far "excellent."

Although the study is not designed to test the efficacy of the combination, 31 evaluable patients have completed the full 18 weeks of treatment at different doses up to 600 micrograms a day.

Of those, the company said, 27 showed a decrease in prostate specific antigen (PSA) levels of more than 30% within three months of starting treatment.

That translates into a response rate to the combination of 87%, which is higher than the 65% response rate seen in clinical trials of docetaxel alone.

Even though this has nothing to do with Peyronie's directly, many guys with Peyronie's are also concerned with the issue of Prostate Cancer and any new successful approaches in the treatment of Prostate Cancer is certainly welcome news for the members of this community.  Do note that the vitamin D being used is NOT off the shelf Vitamin D. It is a special form being used specifically for this purpose.  The usual forms of vitamin D will NOT make Prostate Cancer better and are likely to make it worse.  - George

[Hitman]

Zinc citrate seems to be also beneficial in prostate cancer

[dan]

Hi everyone

I'm new here so hope this is the right place to ask. Do any of you know of reputable places where I might purchase Pentoxifylline online?

I've noticed a couple of members here have mentioned that they get theirs online, and I'd like to go down that route whilst I locate a specialist urologist

Thanks very much

Dan

[newguy]

Dan -  I bought mine from http://www.inhousepharmacy.co.uk . It's not on the main site, but if you email them, they can get it for you. I keep emailing concerning actually placing on the site for the sake of convenience, but they haven't exactly proved to be speedy regarding this request.

[gerMike]

Is it of difference to take 4x 300mg Pentox instead 3x 400mg? The peak blood levels imo are different. For me pentox seems not to help to stop the condition from worsening. Thats why I bothered with that question. If I take 400mg instead 300mg its a bit different, mostly I get a faster heartbeat and my appetite is lower or absent. So taking 300mg at once is more comfortable for me with less side effects but I'm really unsure whether the good effects of it are affected too.

[nemo]

Dan, I've oredered Pentox (Trental) several times from mexmeds4you.com, a Mexican online pharmacy.  I've found them to be reliable and legit.  

Nemo

[Iceman]

Is it of difference to take 4x 300mg Pentox instead 3x 400mg? The peak blood levels imo are different. For me pentox seems not to help to stop the condition from worsening. Thats why I bothered with that question. If I take 400mg instead 300mg its a bit different, mostly I get a faster heartbeat and my appetite is lower or absent. So taking 300mg at once is more comfortable for me with less side effects but I'm really unsure whether the good effects of it are affected too.

germike - are you saying that youve had no noticeable benefit from pentox - even pain reduction??

[newguy]

I think Pentox is more effective in some rather others. That said there is sound reason for thinking that it can be of use, and therefore I'd always encourage people to take it, especially in the early stages of the disease.

[bluth]

In a followup to my previous message, after some badgering it now appears that Pentox will be available on the http://www.inhousepharmacy.co.uk/ website in around a weeks time. This is good news for those in the UK and Europe. I'm unsure of whether it will be added to the US site, but hopefully it will be.  

Is it available yet? This would be great for those of us in Europe. I haven't seen it on the site yet.

[bluth]

Is there any better study out yet detailing the positive effects of Pentox except the one from Dr. Lue with one patient?

I am seeing a urologist soon and last time that study didn't help in getting any Pentox (which I now get online instead).

[newguy]

Bluth - To my knowledge, it is available there (as I ordered months ago). I keep pestering the site owner to place it on the site, and it appears that it will happen, I'm just not sure when. If you send an email via the site they can get it for you though. Maybe that will tip the balance, and they'll finally add it .


As for your comments about pentox studies, it would certainly be helpful. Much of what is known relates to one case, or has a lot of theory behind it but nothing solid. Still, the doctor pdf detailing pentox as ,oderately helpful is at least somewhat positive, because it suggests that it was been of use in treating patients.

It's no doubt quite difficult to demonstrate success treating this disease, because if treatment is delivered before deformity develops, then it's not easy to tell how much a potential problem has been lessened. If it's given too far into the disease, maybe the benefits will be minimal. It's a disease whose fingerprint varies for each individual, and as such it's probably not the easiest thing in the world to research.

[newguy]

In the inflammatory stage, ibuprofen can no doubt be of use to people. It doesn't exactly go easy on the stomach though, and you have to be very careful with dosing. I mentioned topical ibuprofin once before, but am returning to it now after a few studies I've read up on. The studies appear to state that topical ibuprofen is as useful against inflammation as the oral version. This is surely positive, as it can be applied locally and much less of it is absorbed into the blood. It's of course hard to tell how deep it penetrates, but the data must at least suggest that it penetrates as well locally as oral ibuprofen does across the whole body. I'm not suggesting that this is a powerful tool againsty peyronie's, but rather that side effects can possibly be limited by choosing topical over oral.

What are your views?

http://www.medicine.ox.ac.uk/bandolier/booth/painpag/topical/topkin.html (Topical or oral non-steroidal anti-inflammatories in soft tissue injury)

This brief review confirms the view of others [2], that the maximum values found after topical administration of NSAIDs is a small fraction of that expected after usual oral doses of the same NSAID. These low systemic concentrations probably account for the low occurrence of gastrointestinal adverse events with topical NSAIDs.

As best we can tell, synovial fluid concentrations are likely to reflect blood concentrations because this is a highly vascularised compartment. For instance, when topical diclofenac was applied to one knee in a randomised and double blind trial [3], the concentration of diclofenac in the untreated knee was almost the same as that in the treated knee.

However, concentrations of NSAID in tissue, particularly meniscus and cartilage, were very much higher after topical than oral administration, indicating that direct absorption through the skin into tissues of the joint does occur.

[Hawk]

Is there any better study out yet detailing the positive effects of Pentox except the one from Dr. Lue with one patient?

I am seeing a urologist soon and last time that study didn't help in getting any Pentox (which I now get online instead).

https://www.peyroniesforum.net/index.php/topic,772.0.html

[gerMike]

germike - are you saying that youve had no noticeable benefit from pentox - even pain reduction??

Unfortunately this is exactly the case for me. My condition gets worse every month. New nodules form. I even suspect that the combination of Pentox and strong erections is not good because I found new problems nearly everytime after such occurrence.

[Starting2looseHope]

My doctor told me today that i am in the beginning stages of Peyronies. The bending affect is only noticeable when semi erect or weak erection. He took me off vitamin E 400 units two times a day and put my on a colchinine .6 mg 3 times a day, along with a mutilvitamin that contains 60 u that i take once a day. He said this is a "minor" case. He mentioned something about adding on IB profen or motrin along with the cochicine? Has anyone heard of this. Should i continue to take the vitamin E. Any comments about the colchicine and motrin in early stages?