Verapamil injections - problem with anesthetic (Lidocaine - Bupivacaine/Marcain)

[onemillion]

I have just completed a cycle of 6 verapamil injections, mostly 1 week apart from each other.
I have a problem with the anesthetic:

1st shot - LIDOCAINE - worked fine, zero pain, felt VERY dizzy
2nd shot - LIDOCAINE - worked fine, zero pain, little dizzy
3rd shot - LIDOCAINE - did not really work.. a lot of pain
4th shot - BUPIVACAINE (MARCAIN) – worked fine, zero pain, no dizzy at all - this is when my hopes went high
5th shot - BUPIVACAINE (MARCAIN) – worked only partially, pain, no dizzy at all - disappointed
6th shot – BUPIVACAINE (MARCAIN) - worked only partially, pain, no dizzy at all

In the end due to pain doctor could not inject verapamil all around/inside the plaque.. hence this issue is affecting the efficacy of the treatment.
I cannot believe that my body became immune to these anesthetics only after very few shots, it just does not make sense.
Doctor said that it might be due to the inflammation from having all these shots.

Please advise.. I plan to take another cycle of verapamil but if it cannot be injected properly there is no point.

[LWillisjr]

are you sure that they are using Verapamil? That is an older drug I didn't think was used any longer. Xiaflex is the newer updated drug.

[onemillion]

Hi,

yes it's verapamil, because I live in Indonesia, there was nothing here, I had to go to Singapore to get the Verapamil injections.... Xiaflex is not available outside of the USA.

But my question is very much about the anesthetic.. how come it loses effectiveness? after only few shots...