Cialis is less effective over time ?

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GaussRifle

I started taking tadalfil/cialis 5mg daily early 2021 during acute phase of Peyronies and it gave me good nocturnal erections . I never tried sex on it , but on masturbating I could tell it was helping a lot with the blood flow and how warm it used to feel so the the blood rushing in. Ate it from 2021- end of 22. Then did not have mutch of it in 2023, skipped a few months . Fast forward to today and I it just doesn't have the same effect it feels to me. It doesn't seem as potent as before . A couple of things could be possible -

1) Is it possible RestoreX desensitized my glans a bit ? On cialis earlier I tried clamping my glans, it would immoderately give me an erection , now my glans seems used to it and doesn't try to induce an erection on clamping.  But this would not impact my nocturnal erections so can't be it .
2) peyronies worsened ?  . I don't see a new relapse , only some nodules that hardened after xialflex injections over the years despite restore x . No curve change. ( really hoping that's not it )
3) Earlier I was on cialis ( brand) and now on generic tadalafil , maybe it does make a  difference ?
4) there is indeed some cialis tolerance that builds for it to not work the same ?

Despite daily 5 mg cialis , I only wake up with a chubby , not a full fledged erection like I used to when I just started cialis.

*This nightmare never ends. Any ideas ?
26 year old
45-50 degree downward curve with an indentation on one side when erect.
Using RestoreX and Xiaflex injections
Taking coq10 with daily Cialis 5mg.

Vesley_kim

I'm sorry to hear about your struggles. It's great that you've found some relief in the past, but I understand your concern with the recent changes. Here are a few thoughts:

RestoreX desensitization: It's possible that prolonged use of devices like RestoreX could cause some changes in sensitivity, but as you mentioned, this would likely not affect your nocturnal erections.

Peyronie's disease progression: It's reassuring that you haven't noticed a significant relapse or curve change, but any hardening of nodules could potentially affect overall penile health and function.

Brand vs. Generic: There can be differences in the effectiveness of brand-name medications compared to their generic counterparts, even though they contain the same active ingredients. Sometimes the fillers or the absorption rate can vary.

Cialis tolerance: Tolerance to medications can develop over time, which might explain why it doesn't feel as potent as it used to.

Given these possibilities, it might be a good idea to:

Consult your doctor: They can provide a more tailored analysis and perhaps adjust your treatment plan.
Consider medication quality: Always use reputable pharmacies to ensure you are getting genuine medications. The effectiveness can vary greatly between reliable and less reputable sources.


I hope you find some answers and relief soon. Take care!
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Peypt

I experienced the same thing with Cialis 5mg
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