Supplements - how many is too many?

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DaneS89

Guys, does this supplement and meds regime sound excessive to you or actually reasonable? As the subject line queries, how many is too many? This is the full list of supplements, herbs, vitamins and meds I take...

Daily:

Cialis - 5mg
Trental - 400mg x 3

L-Citrulline - 1g
L-Arginine - 1g
L-Carnitine - 1.5g

Propolis - 500mg
Pygnogenol - 100mg

Coq10 - 100mg
Omega 3 - 2000mg?

Vitamin E - 200 IU
Vitamin C - 1000mg

Sometimes/experimental/recent additions:

Magnesium - 100mg
Multivitamin
Mens libido complex (contains Tribulus, Epimedium, Gingko etc)

Zinc - 15mg
Benfotiamine - 150mg

Other:

Low dose aspirin after I've had sex or masturbated.

I take meds for anxiety and depression also which adds a few more pills to the stack...

So that's the list. I know its a lot. It feels like a lot. I'm taking pills every couple of hours it seems. It's constant and I'm getting tired of it. I want to slim this list down to the bare essentials, but I am loath to take out anything out for fear that I am "missing out" on something important.

I'm a bit embarrassed by it to be honest, but I'm sure at least some of you can understand the sort of desperate thinking that compels us to do and take almost anything in the hope that something in the mix might just work.

I'd be keen to hear your thoughts about this. How many do you take (if that's not a rude question)? Opinions from other supplement enthusiasts (?) on how to tweak and refine the list and optimal dosages would be especially appreciated. Cheers.




 
Peyronies onset - Oct 2022 - initial plaque mid shaft resulted in approx 25 degree bend, newer smaller plaques have developed since
Treatment regime - Trental, Cialis, supplements alongside diet and lifestyle changes
Age 34

Sonic

Does the anxiety meds give any erection problems? I assume you watch Neo's videos due to the supplement list?

This is just a personal opinion. Remove the L-Arginine. You do not need this if you take L-Citruline. L-citruline is the superior choice always. It converts more NO than L-Arginine. Also remove the L-Carnitine, if you take this for Peyronies it's useless. Raise your L-Citruline dosage to at least 3g per day. If you get good erections with just trental and L-Citruline perhaps it would be wise to remove the cialis as well. But if you feel you need the Cialis keep taking it. I do not know too much about benfotiamine to give an opinion but other than what I mentioned your list is good.

Pycnogenol, Citruline and Trental should give you very good blood flow. coq10 is a very good supplement, Propolis is also good for the immune system, I think it's a good list of supplements but it's all down to you and how you feel. Personally I could never take that much.
30 years. Sudden rightwards curve detected in June 2020
narrowing on right side and about a 20° curve to the right.
Weakened erections and instability due to narrowing.

DaneS89

Hey man. Thanks for your feedback. Good call on the L-arginine. I'll probably quit that once my current supply runs out, which will be soon.  L-carnitine is a more recent addition that I'm still trialling. Using it in an attempt to relieve symptoms of neuropathy more so than to treat peyronies itself, as neuropathy and numbness are more bothersome to me than just about any other aspect of this condition. Thats why benfotiamine is in the mix too, for that purpose. And I have actually noticed a positive difference with increased sensation. The thing is, I started both of them at the same time so I don't know which one is working to have that effect...or if it's just placebo...or something else. But yeah, out of all the supplements I take L-car is the most unpleasant - it stinks and goes gross and clumpy in the bottle, so it will probably go too.

Vitamin E is another one I'm eyeing off for revision. Bit concerned about prostate cancer risk with that one as I have a family history of that illness. And I'm not sure it would be doing anything useful - even if it could - at the low dose I'm taking it in. The multi seems like an optional extra too.

Yes I do watch Neoman's videos. Pygnogenol and Benfotiamine are part of my regime based on his recommendations. The rest of them I was already taking before I found his channel. I agree with you, Propolis, Pygnogenol and Coq10 are all great - holy grail status for me.

Curious as to why you think Cialis is dispensable before Trental. In my mind, it's the other way around. Not challenging you, I'm genuinely interested what your rationale is behind that if you care to share :)

Re. anxiety and depression meds...it's a complicated sort of dance I have to do with those. I need them to help manage my anxiety and depression symtoms, which if left unchecked would ruin my sex drive and as result EQ would suffer. There was a time last year when I went off my meds entirely and it was disastrous, both for mental and sexual health. I have been super careful to only choose meds that are known to have a very low chance of causing sexual/erectile dysfunction. And so while each of them could *theoretically* through one mode of action or another hinder erectile function, in other ways and through other mechanisms they help it. And they all work to reduce anxiety and depression symptoms, so overall its a net benefit.
Peyronies onset - Oct 2022 - initial plaque mid shaft resulted in approx 25 degree bend, newer smaller plaques have developed since
Treatment regime - Trental, Cialis, supplements alongside diet and lifestyle changes
Age 34

Sonic

Quote from: DaneS89 on January 09, 2024, 05:27:14 AMCurious as to why you think Cialis is dispensable before Trental. In my mind, it's the other way around. Not challenging you, I'm genuinely interested what your rationale is behind that if you care to share :)

Yeah, Vitamin - E is absolutely useless, Just when I got diagnosed I took it for 6 months straight, does absolutely nothing. As for Cialis my suggestion was only to remove it if you have solid EQ. Pycnogenol, Trental and L-citruline should provide a massive blood flow boost some patients are different than others where their erections are not impacted as much as someone else. If you feel you still need the cialis to have good EQ then definitely stick with it.
30 years. Sudden rightwards curve detected in June 2020
narrowing on right side and about a 20° curve to the right.
Weakened erections and instability due to narrowing.

DaneS89

Ah I see, thanks for clarifying. Yeah they seem to work in different ways to enhance blood flow for me. Trental has a slow but steady trickle effect, whereas Cialis is more like a surge. My EQ is pretty good albiet somewhat unpredictable. Some days - or weeks even - are great with frequent strong erections. At other times, its like...asleep, and can't be roused. Can't or doesn't want to be. Has a lot to do with mood and how I sleep, but also ejaculation frequency. I'm coming to realise that less is probably best...
Peyronies onset - Oct 2022 - initial plaque mid shaft resulted in approx 25 degree bend, newer smaller plaques have developed since
Treatment regime - Trental, Cialis, supplements alongside diet and lifestyle changes
Age 34

curvedcarnivore

Is Pygnogenol and Pine Bark Extract the exact same thing?
41 years old.
I discovered a left curve several months ago.
GP inspected my penis and diagnosed Peyronie's.
My urologist wants me to give treatment another three months.
Treatment: Keto + heat + RestoreX + Cialis + supplements.

Pfract

Danes89:

The list of supplements is big indeed. According to the latest recommendations from the guidelines, here is what Dr. Landon Trost has to say about those treatments on his website: https://malefertilityandpeyroniesclinic.com/peyronies/treatments/

The reality is a lot of those pills don't do anything to help with peyronies and are old advice that you find around. You can continue taking them as they improve your erections if you don't have access to a prescription for Viagra or Cialis, but just be aware of that.
You can also have a look at the more complete list of the current guidelines from the website of the American Urological Association itself.

https://www.auanet.org/guidelines-and-quality/guidelines/peyronies-disease-guideline

 

DaneS89

Hi Pfract,

Something in the mix is definitely working so I will continue :D I am not particularly deterred by a lack of concrete scientific evidence. There is not the same financial incentive (or industry demands) to study and promote natural supplements. The science isn't exactly rock solid or settled even when it comes to the mainstream approved treatments that are commonly prescribed for Peyronies. Nor is there complete consensus among experts in the field itself about what does and doesn't work. None of it has been studied exhaustively, really.

For each of the supplements on that list, there is at least some research and rationale behind their use. For many, if not all of them, the mode-of-action by which they could *possibly* help with peyronies is fairly well understood. In most cases that's antioxidant and/or anti-inflammatory activity, circulatory support etc. We know this to be helpful, if not just to arrest peyronies, but to promote overall good health and assist the body in other ways. I'm still in the stage where conservative/oral treatments could make a difference and turn things around for the better. So if it's not hurting me, and is possibly even helping me, then I have no reason to change tack.
Peyronies onset - Oct 2022 - initial plaque mid shaft resulted in approx 25 degree bend, newer smaller plaques have developed since
Treatment regime - Trental, Cialis, supplements alongside diet and lifestyle changes
Age 34

DaneS89

Curvedcarnivore - yes, Pygnogenol is Pine Bark (Pinus Pinaster), but not all Pine Bark is Pygnogenol. Pygnogenol is a patent/trademarked name that indicates the product is always sourced from Pinus Pinaster. There are other, cheaper Pine Bark products on the market but they can come from other species of Pine.  
Peyronies onset - Oct 2022 - initial plaque mid shaft resulted in approx 25 degree bend, newer smaller plaques have developed since
Treatment regime - Trental, Cialis, supplements alongside diet and lifestyle changes
Age 34

curvedcarnivore



Thank you for this. Does it matter which I get?
41 years old.
I discovered a left curve several months ago.
GP inspected my penis and diagnosed Peyronie's.
My urologist wants me to give treatment another three months.
Treatment: Keto + heat + RestoreX + Cialis + supplements.

DaneS89

Hey curvedcarnivore,

Most of the scientific interest and research papers are focussed on Pinus Pinaster extract specifically. It's also known as French Maritime Pine Bark Extract. iHerb has a good range and super fast shipping (less than one week) to Australia (I saw on your profile that you're a fellow Aussie).

Random question back to you...assuming you on a carnivore diet as your profile name suggests, where do plant extracts fit in with that?  
Peyronies onset - Oct 2022 - initial plaque mid shaft resulted in approx 25 degree bend, newer smaller plaques have developed since
Treatment regime - Trental, Cialis, supplements alongside diet and lifestyle changes
Age 34

curvedcarnivore

Quote from: DaneS89 on Yesterday at 07:28:25 AMHey curvedcarnivore,

Most of the scientific interest and research papers are focussed on Pinus Pinaster extract specifically. It's also known as French Maritime Pine Bark Extract. iHerb has a good range and super fast shipping (less than one week) to Australia (I saw on your profile that you're a fellow Aussie).

Random question back to you...assuming you on a carnivore diet as your profile name suggests, where do plant extracts fit in with that?  

Thanks, so I need the Pygnogenol version?

I'll take a look at iHerb. As running low on cash trying to treat this horrible disease.

Also, I had to stop carnivore. Four months of diarrhoea was not for me.  
41 years old.
I discovered a left curve several months ago.
GP inspected my penis and diagnosed Peyronie's.
My urologist wants me to give treatment another three months.
Treatment: Keto + heat + RestoreX + Cialis + supplements.

DaneS89


Yeah mate, Pygnogenol is the one you want to go for  :)  
Peyronies onset - Oct 2022 - initial plaque mid shaft resulted in approx 25 degree bend, newer smaller plaques have developed since
Treatment regime - Trental, Cialis, supplements alongside diet and lifestyle changes
Age 34