Peyronies articles: review (Compilation)

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bentoboy

Hi there,

I would like to create a list of all (or at least of the most relevant ones) academic articles/expected clinical studies/news articles etc. published in the recent years on Peyronies.

I do not know about you but for me it is super useful to have a list of all articles that have been published recently and then update it every month - just to keep track of all developments in the area.

Important Clinical trials:

Stem Cell Treatment of Peyronie´s Disease (Denmark):
� posted: 25 February 2021; 22 participants
� expected completion: May 30, 2024
link

PRP for treatment of Peyronies (US):
� posted: August 23, 2020; 80 participants; randomised
� expected completion: April 1, 2024
link

Academic articles – 2023

January 2023:

Yang CH, Lin DY, Lin YS, Hsu CY, Tung MC, Tan KT, Ou YC. The Immunological Microenvironment and the Emerging Role of Stem Cells Therapy in Peyronie's Disease: A Systematic Narrative Review. Int J Mol Sci. 2023 Jan 1;24(1):777. doi: 10.3390/ijms24010777. PMID: 36614220; PMCID: PMC9821411.

February 2023:

Reddy AG, Dai MC, Song JJ, Pierce HM, Patel SR, Lipshultz LI. Peyronie's Disease: An Outcomes-Based Guide to Non-Surgical and Novel Treatment Modalities. Res Rep Urol. 2023 Feb 2;15:55-67. doi: 10.2147/RRU.S278796. PMID: 36756281; PMCID: PMC9901485.

Kulkarni Y, Green B, Pattillo C, Stirland I, Flores A, Ziegelmann M, Kohler T, Helo S, Trost L. Efficacy of collagenase Clostridium histolyticum in men with congenital penile curvature. J Sex Med. 2023 Feb 14;20(2):194-199. doi: 10.1093/jsxmed/qdac006. PMID: 36763911.

Li MK, Sigalos JT, Yoffe DA, Modiri N, Hu MY, Gaither TW, Santamaria A, Walker DT, Regets KV, Mills JN, Eleswarapu SV. Multiple courses of intralesional collagenase injections for Peyronie disease: a retrospective analysis. J Sex Med. 2023 Feb 14;20(2):200-204. doi: 10.1093/jsxmed/qdac030. PMID: 36763912.

Falcone M, Preto M, Peretti F, Gontero P, Pyrgidis N, Sokolakis I, Hatzichristodoulou G. The use of collagen fleece to correct residual curvature during inflatable penile prosthesis implantation (PICS technique) in patients with complex Peyronie disease: a multicenter study. J Sex Med. 2023 Feb 14;20(2):229-235. doi: 10.1093/jsxmed/qdac003. PMID: 36763916.

Searl T, Ohlander S, McVary KT, Podlasek CA. Pathway analysis of microarray data from corpora cavernosal tissue of patients with a prostatectomy or Peyronie disease in comparison with a cavernous nerve-injured rat model of erectile dysfunction. J Sex Med. 2023 Feb 14;20(2):139-151. doi: 10.1093/jsxmed/qdac019. PMID: 36763930.

Gundogdu G, Nguyen T, Namasivayam A, Starek S, Gelman J, Mauney JR. Characterization of a novel rabbit model of Peyronie's disease. Int J Impot Res. 2023 Feb 13. doi: 10.1038/s41443-023-00671-y. Epub ahead of print. PMID: 36782023.

Spirito L, Manfredi C, La Rocca R, Napolitano L, Preto M, Di Girolamo A, Arcaniolo D, De Sio M, Creta M, Longo N. Long-term outcomes of extracorporeal shock wave therapy for acute Peyronie's disease: a 10-year retrospective analysis. Int J Impot Res. 2023 Feb 14. doi: 10.1038/s41443-023-00673-w. Epub ahead of print. PMID: 36788352.

Sicignano E, Imperatore V, Sciorio C, Di Girolamo A. The clinical potential of flavonoids in Peyronie's disease. J Basic Clin Physiol Pharmacol. 2023 Feb 15;34(2):121-123. doi: 10.1515/jbcpp-2023-0006. PMID: 36790332.

Vieiralves RR, Schuh MF, Favorito LA. Low-intensity extracorporeal shockwave therapy in the treatment of erectile dysfunction - a narrative review. Int Braz J Urol. 2023 Feb 15;49. doi: 10.1590/S1677-5538.IBJU.2023.9904. Epub ahead of print. PMID: 36794846.

Bole R, Alom M, Habashy E, Ahmed M, Ziegelmann M, Kohler T, Helo S. The clinical significance of imperfection: is idiopathic corporal asymmetry related to curvature during penile prosthesis placement? Int J Impot Res. 2023 Feb 16. doi: 10.1038/s41443-023-00669-6. Epub ahead of print. PMID: 36797455.

Kothiya AB, Adlakha N. Cellular nitric oxide synthesis is affected by disorders in the interdependent [Formula: see text] and [Formula: see text] dynamics during cystic fibrosis disease. J Biol Phys. 2023 Feb 22. doi: 10.1007/s10867-022-09624-w. Epub ahead of print. PMID: 36811722.

Brant A, Basourakos SP, Lewicki P, Kang C, Marinaro J, Punjani N, Kashanian JA. Real-world practice in Peyronie's disease management: Results from a national survey of urologists. Andrology. 2023 Feb 23. doi: 10.1111/andr.13414. Epub ahead of print. PMID: 36815582.

Schifano N, Capogrosso P, Antonini G, Baldini S, Scroppo F, Salonia A, Zerbinati N, Dehò F. The Application of Hyaluronic Acid Injections in Functional and Aesthetic Andrology: A Narrative Review. Gels. 2023 Feb 1;9(2):118. doi: 10.3390/gels9020118. PMID: 36826290; PMCID: PMC9957416.

Ziegelmann M. Is there a new role for oral therapy to treat peyronie's disease? Commentary on Daily low-dose tadalafil may reduce the penile curvature progression rate in patients with acute Peyronie's Disease: a retrospective comparative analysis. Int J Impot Res. 2023 Feb 24. doi: 10.1038/s41443-023-00684-7. Epub ahead of print. PMID: 36828955.


March 2023:

Levine LA. What's the new thing for surgical treatment of Peyronie's disease? Extratunical grafting. J Sex Med. 2023 Mar 31;20(4):416-417. doi: 10.1093/jsxmed/qdac039. PMID: 36763947.

Ziegelmann M, Hu Y, Xiang Q, Liu G, McLane MP, Trost L. Incremental Treatment Response by Cycle With Collagenase Clostridium Histolyticum for Peyronie's Disease: A Pooled Analysis of Two Phase 3 Trials. Urology. 2023 Mar 1:S0090-4295(23)00182-6. doi: 10.1016/j.urology.2023.02.019. Epub ahead of print. PMID: 36863600.

Paulis G, Paulis A, Perletti G. Congenital penile curvature as a possible risk factor for the onset of Peyronie's disease, and psychological consequences of penile curvature. Arch Ital Urol Androl. 2023 Mar 15;95(1). doi: 10.4081/aiua.2023.11238. PMID: 36924365.

Pakpahan C, Ilhamsyah I, Supardi S, Narulita P, Agustinus A, Darmadi D. The interplay between neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, erectile dysfunction, and Peyronie's disease: A meta-analysis of observational studies. Arch Ital Urol Androl. 2023 Mar 15;95(1). doi: 10.4081/aiua.2023.11162. PMID: 36924369.

April 2023:

Conlon WJ, Herzog BJ, Hellstrom WJG. Residual penile curvature correction by modeling during penile prosthesis implantation in Peyronie's disease patients. Int J Impot Res. 2023 Apr 13. doi: 10.1038/s41443-023-00694-5. Epub ahead of print. PMID: 37055523.

Chung E, Moon DG, Hui J, Chang HC, Hakim L, Nagao K, Tan R, Mak SK, Tantiwongse K, Lin H, Mai DBT, Nguyen Q, Tan HM, Sato Y, Jiann BP, Park K, Xin ZC, Park HJ. Clinical recommendations on penile reconstructive and prosthetic surgery: a consensus statement from the Asia-Pacific Society of Sexual Medicine. Sex Med. 2023 Apr 11;11(2):qfad003. doi: 10.1093/sexmed/qfad003. PMID: 37056790; PMCID: PMC10086569.

Thomas J, Sencaj M, Ghomeshi A, Zucker IJ, Best JC, Ramasamy R. Stem-Cell, Shockwave, and Platelet Rich Plasma Therapy for the Treatment of Erectile Dysfunction and Peyronie's Disease: A Survey of Clinics Across the US. Urology. 2023 Apr 17:S0090-4295(23)00323-0. doi: 10.1016/j.urology.2023.01.061. Epub ahead of print. PMID: 37076023.

Feng CL, Langbo WA, Anderson LK, Cao D, Bajic P, Amarasekera C, Wang V, Levine LA. Subcoronal inflatable penile prosthesis implantation: indications and outcomes. J Sex Med. 2023 Apr 19:qdad049. doi: 10.1093/jsxmed/qdad049. Epub ahead of print. PMID: 37076135.

Ilg MM, Ralph DJ, Cellek S. Statins synergize with phosphodiesterase type 5 inhibitors but not with selective estrogen receptor modulators to prevent myofibroblast transformation in an in vitro model of Peyronie's disease. J Sex Med. 2023 Apr 20:qdad051. doi: 10.1093/jsxmed/qdad051. Epub ahead of print. PMID: 37082866.

News articles:

January 2023:

• Scientists Reverse Erectile Dysfunction in Pigs Using Synthetic Tissue Link

February 2023:

• Endo Launches "Man With a Plan" Campaign to Support Men With Symptoms of Peyronie's Disease Link

April  2023:

• Early-onset diabetes appears to affect Peyronie disease severity  Link

 
27 y. o. Peyronies since 2020: S curvature with the top part tilting to the left - 15*. Multiple nodules and scarring on each side, mild hourglassing. Getting worse every few months, losing width. Normal penile function. Enlarged veins.

FrankPD

It's nice to know there's that many studies.  If felt nearly nonexistent to me even after being 16 months since diagnosis.  Most don't even know this exists.  

Thanks!
I have a girlfriend
Age 48, No injury
Diagnosis January 2022  
Six plaques
Hourglassing when flaccid and semi-erect
Only have my congenital curve
Massaging with vitamin E cream twice a day 
5mg Tadalafil, Healthy diet
Discomfort/aching sometimes

bentoboy

Not many new articles for May. Here you go anyway:

May 2023

Paulis G, Paulis A. Chronic prostatitis as possible risk factor for Peyronie's disease: Psychological, sexual and prostatitis-like symptoms in patients with Peyronies Disease. Arch Ital Urol Androl. 2023 May 31:11406. doi: 10.4081/aiua.2023.11406. Epub ahead of print. PMID: 37259816.

Henry AJ, Holler JT, Lui J, Breyer BN, Ziegelmann M, Cohen T, Smith RP, Yeaman C, Winkelman AJ, Villanueva C, Kern NG. Do patients with Peyronie's disease perceive penile curvature in adults and children differently than the general population? J Sex Med. 2023 Jun 2:qdad073. doi: 10.1093/jsxmed/qdad073. Epub ahead of print. PMID: 37279444.
27 y. o. Peyronies since 2020: S curvature with the top part tilting to the left - 15*. Multiple nodules and scarring on each side, mild hourglassing. Getting worse every few months, losing width. Normal penile function. Enlarged veins.

bentoboy

June 2023

Wilson SK, Wen L, Rossello M, Maria P, Carrion R, Perito P, Ralph D, Antonini G, Carvajal A, Ozturk MI, Chung E. Initial safety outcomes for the Rigicon Infla10® inflatable penile prosthesis. BJU Int. 2023 Jun;131(6):729-733. doi: 10.1111/bju.15960. Epub 2023 Mar 6. PMID: 36633050.

Kothiya AB, Adlakha N. Cellular nitric oxide synthesis is affected by disorders in the interdependent [Formula: see text] and [Formula: see text] dynamics during cystic fibrosis disease. J Biol Phys. 2023 Jun;49(2):133-158. doi: 10.1007/s10867-022-09624-w. Epub 2023 Feb 22. PMID: 36811722; PMCID: PMC10160313.

Mitsui Y, Yamabe F, Hori S, Uetani M, Kobayashi H, Nagao K, Nakajima K. Molecular Mechanisms and Risk Factors Related to the Pathogenesis of Peyronie's Disease. Int J Mol Sci. 2023 Jun 14;24(12):10133. doi: 10.3390/ijms241210133. PMID: 37373277; PMCID: PMC10299070.

Lee HY, Pyun JH, Shim SR, Kim JH. Medical Treatment for Peyronie's Disease: Systematic Review and Network Bayesian Meta-Analysis. World J Mens Health. 2023 Jun 15. doi: 10.5534/wjmh.230016. Epub ahead of print. PMID: 37382281.

Khooblall P, Bole R, Lundy SD, Bajic P. Expanded Utilization of Intralesional Therapies for Treatment of Peyronie's Disease. Res Rep Urol. 2023 Jun 21;15:205-216. doi: 10.2147/RRU.S386340. PMID: 37366388; PMCID: PMC10290860.

Ilg MM, Ralph DJ, Cellek S. Statins synergize with phosphodiesterase type 5 inhibitors but not with selective estrogen receptor modulators to prevent myofibroblast transformation in an in vitro model of Peyronie's disease. J Sex Med. 2023 Jun 28;20(7):925-934. doi: 10.1093/jsxmed/qdad051. PMID: 37082866.

Henry AJ, Holler JT, Lui J, Breyer BN, Ziegelmann M, Cohen T, Smith RP, Yeaman C, Winkelman AJ, Villanueva C, Kern NG. Do patients with Peyronie's disease perceive penile curvature in adults and children differently than the general population? J Sex Med. 2023 Jun 28;20(7):998-1003. doi: 10.1093/jsxmed/qdad073. PMID: 37279444.

Bole R, Bajic P. Editorial CommentRe: Stem-Cell, Shockwave, and Platelet Rich Plasma Therapy for the Treatment of Erectile Dysfunction and Peyronie's Disease: A Survey of Clinics Across the USA. Urology. 2023 Jun 30:S0090-4295(23)00325-4. doi: 10.1016/j.urology.2023.01.062. Epub ahead of print. PMID: 37394358.

July 2023

Roadman D, Wang V, Langbo W, Paddock D, Levine L. Predictors of hinge effect in patients with Peyronie's disease. J Sex Med. 2023 Jul 17:qdad087. doi: 10.1093/jsxmed/qdad087. Epub ahead of print. PMID: 37460401.

Rosenberg JE, Ergun O, Hwang EC, Risk MC, Jung JH, Edwards ME, Blair Y, Dahm P. Non-surgical therapies for Peyronie's disease. Cochrane Database Syst Rev. 2023 Jul 17;7(7):CD012206. doi: 10.1002/14651858.CD012206.pub2. PMID: 37490423; PMCID: PMC10351344.

Roadman D, Wang V, Beer A, Levine L. A contemporary assessment of the evaluation and management of patients presenting to a tertiary medical center with Peyronie's disease. Int J Impot Res. 2023 Jul 19. doi: 10.1038/s41443-023-00738-w. Epub ahead of print. PMID: 37468535.

Rahardjo HE, Märker V, Tsikas D, Kuczyk MA, Ückert S, Bannowsky A. Fibrotic Diseases of the Human Urinary and Genital Tract: Current Understanding and Potential Strategies for Treatment. J Clin Med. 2023 Jul 19;12(14):4770. doi: 10.3390/jcm12144770. PMID: 37510885; PMCID: PMC10381287.

Osman MM, Hammad MA, Barham DW, Toma R, El-Khatib FM, Dianatnejad S, Nguyen J, Towe M, Choi E, Wu Q, Banavar G, Cai Y, Moura P, Shen N, Vuyisich M, Yafi NR, Yafi FA. Comparison of the gut microbiome composition between men with Peyronie's disease and a matched cohort: a pilot study. Int J Impot Res. 2023 Jul 20. doi: 10.1038/s41443-023-00737-x. Epub ahead of print. PMID: 37474796.

Dell'Atti L, Ronchi P. Low-intensity laser diode plus extracorporeal shock wave therapy: a new treatment strategy in the management of Peyronie's disease. World J Urol. 2023 Jul 25. doi: 10.1007/s00345-023-04533-6. Epub ahead of print. PMID: 37490060.

Park SH, Wilson SK, Wen L. Subcoronal Incision for Inflatable Penile Prosthesis Does Not Risk Glans Necrosis. J Urol. 2023 Jul 25:101097JU0000000000003619. doi: 10.1097/JU.0000000000003619. Epub ahead of print. PMID: 37490615.

August 2023

Schifano N, Capogrosso P, Boeri L, Fallara G, Chiappini S, Rewhorn M, Cakir OO, Harvey H, Castiglione F, Alnajjar HM, Muneer A, Deho' F, Schifano F, Montorsi F, Salonia A. Are finasteride-related penile curvature/Peyronie's disease Adverse Event Reports worthy of further clinical investigation? Disproportionality analysis based on both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) pharmacovigilance databases. Int J Impot Res. 2023 Aug;35(5):465-471. doi: 10.1038/s41443-022-00568-2. Epub 2022 May 5. PMID: 35513712.
27 y. o. Peyronies since 2020: S curvature with the top part tilting to the left - 15*. Multiple nodules and scarring on each side, mild hourglassing. Getting worse every few months, losing width. Normal penile function. Enlarged veins.

bentoboy

September

Low P, Wang L, Li KD, Shibley WP, Cedars BE, Holler JT, Enriquez A, Sadeghi-Nejad H, Amend GM, Breyer BN. Thematic analysis of the psycho-sexual symptoms in patients with Peyronie's disease present on online forums. Int J Impot Res. 2023 Sep;35(6):533-538. doi: 10.1038/s41443-022-00589-x. Epub 2022 Jun 16. PMID: 35710605; PMCID: PMC10499595.

Sischka M, Krueger A, Parikh N, Kohler T, Helo S, Ziegelmann M. Significant Geographic Variation in Access to Certified Collagenase Clostridium histolyticum Injectors for Peyronie's Disease Throughout the United States. Urol Pract. 2023 Sep 7:101097UPJ0000000000000456. doi: 10.1097/UPJ.0000000000000456. Epub ahead of print. PMID: 37788391.

Wang X, Liu H, Tang G, Wu G, Chu Y, Wu J, Cui Y. Updated recommendations on the therapeutic role of extracorporeal shock wave therapy for peyronie's disease: systematic review and meta-analysis. BMC Urol. 2023 Sep 12;23(1):145. doi: 10.1186/s12894-023-01320-8. PMID: 37700253; PMCID: PMC10498627.

Paulis G, Paulis A. Benign prostatic obstruction (BPO) as a possible risk factor for Peyronie's disease (Peyronies Disease). The influence of BPO and Peyronies Disease on mental health. Arch Ital Urol Androl. 2023 Sep 12;95(3):11481. doi: 10.4081/aiua.2023.11481. PMID: 37791559.

Tomioka M, Uno H, Seike K, Iinuma K, Tatsuhiko M. A Case Report of Syphilis That Was Difficult to Distinguish From Penile Carcinoma. Cureus. 2023 Sep 11;15(9):e45029. doi: 10.7759/cureus.45029. PMID: 37829948; PMCID: PMC10566309.

October

Ziegelmann MJ. Penile indentation and hourglass deformities with Peyronie's disease-what can we reasonably offer our patients? J Sex Med. 2023 Oct 3;20(10):1230-1232. doi: 10.1093/jsxmed/qdad105. PMID: 37784214.

Green B, Flores A, Warner J, Kohler T, Helo S, Trost L. Comparison of Collagenase Clostridium histolyticum to Surgery for the Management of Peyronie's Disease: A Randomized Trial. J Urol. 2023 Nov;210(5):791-802. doi: 10.1097/JU.0000000000003634. Epub 2023 Oct 9. PMID: 37811752.
 
27 y. o. Peyronies since 2020: S curvature with the top part tilting to the left - 15*. Multiple nodules and scarring on each side, mild hourglassing. Getting worse every few months, losing width. Normal penile function. Enlarged veins.

bentoboy

October

Dell'Atti L, Slyusar V, Ronchi P. Serum Testosterone Concentration Influences the Response to Extracorporeal Shock Wave Treatment in Men With Peyronie's Disease. Urology. 2023 Oct 11:S0090-4295(23)00881-6. doi: 10.1016/j.urology.2023.09.037. Epub ahead of print. PMID: 37832829.

Cai T, Capece M, Ceruti C, Tiscione D, Puglisi M, Verze P, Gontero P, Palmieri A. The Use of Vacuum Devices as Adjuvant Therapy before and after Penile Curvature Surgery in Patients Affected by La Peyronie's Disease: Results from a Comparative Study. Clin Pract. 2023 Oct 17;13(5):1244-1252. doi: 10.3390/clinpract13050112. PMID: 37887088; PMCID: PMC10605300.

Kraglund R, Durukan E, Giraldi A, Fode M. The association between Peyronie's disease and depression: a scoping review. Sex Med Rev. 2023 Oct 28:qead045. doi: 10.1093/sxmrev/qead045. Epub ahead of print. PMID: 37902293.

Preto M, Falcone M, Plamadeala N, Schifano N, Bettocchi C, Colombo F, Fiordelise S, Vitarelli A, Silvani M, Mondaini N, Paradiso M, Ceruti C, Varvello F, Palumbo F, Avolio A, Antonini G, Corvasce A, Pozza D, Franco G, Bitelli M, Boezio F, Conti E, Caraceni E, Negro C, Carrino M, Vicini P, Ghidini N, Alei G, Italiano E, Timpano M, Polito M, Natali A, Tamai A, Pescatori E, Dehò F, Gideon B, Gontero P, Palmieri A, Capogrosso P. Risk of unfavorable outcomes after penile prosthesis implantation - results from a national registry (INSIST-Erectile Dysfunction). Int J Impot Res. 2023 Oct 31. doi: 10.1038/s41443-023-00784-4. Epub ahead of print. PMID: 37907669.

Pyrgidis N, Sokolakis I, Hatzichristodoulou G. Intermediate-term results of TachoSil grafting to correct residual curvature during inflatable penile prosthesis implantation in patients with Peyronie's disease. Int J Impot Res. 2023 Nov;35(7):647-650. doi: 10.1038/s41443-023-00708-2. Epub 2023 May 5. PMID: 37147483.

November

Green B, Flores A, Warner J, Kohler T, Helo S, Trost L. Comparison of Collagenase Clostridium histolyticum to Surgery for the Management of Peyronie's Disease: A Randomized Trial. J Urol. 2023 Nov;210(5):791-802. doi: 10.1097/JU.0000000000003634. Epub 2023 Oct 9. PMID: 37811752.

Chung E, Blecher G. Perspective: Residual penile curvature correction during penile prosthesis implantation by plication in Peyronie's patients. Int J Impot Res. 2023 Nov;35(7):643-646. doi: 10.1038/s41443-023-00774-6. Epub 2023 Oct 20. PMID: 37864087; PMCID: PMC10622317.

Cevik G, Tozsin A, Tastekin E, Dursun M, Aktoz T, Kadioglu A. The Effect of Pirfenidone on Peyronie Plaques and Erectile Function in a Peyronie's Rat Model. J Coll Physicians Surg Pak. 2023 Nov;33(11):1217-1222. doi: 10.29271/jcpsp.2023.11.1217. PMID: 37926870.

Zucker I, Nackeeran S, Mirza S, Masterson TA. Risk Factors for Penile Fracture After Intralesional Collagenase Clostridium histolyticum in Peyronie's Disease. Urology. 2023 Nov 8:S0090-4295(23)00990-1. doi: 10.1016/j.urology.2023.10.019. Epub ahead of print. PMID: 37949243.

Lehner K, Byrne E, Roshandel MR, Alom M, Helo S, Köhler T, Ziegelmann M. The Discontinuation Rate With Collagenase Clostridium histolyticum for Peyronie's Disease in a High-volume Practice Is Unexpectedly High: Identifying Opportunities for Patient Care Improvement. Urology. 2023 Nov 8:S0090-4295(23)00992-5. doi: 10.1016/j.urology.2023.10.022. Epub ahead of print. PMID: 37949244.

Zhao S, Wu X, Zhang Y, Zhang C. Role of Shear Wave Elastography in the Diagnosis of Peyronie Disease. J Ultrasound Med. 2023 Nov 10. doi: 10.1002/jum.16372. Epub ahead of print. PMID: 37948532.

Capogrosso P, Pozzi E, Russo GI, Hatzichristodoulou G, Cocci A, Falcone M, Martinez-Salamanca JI, Fernández-Pascual E, Candela L, Schifano N, Dehò F, Salonia A; European Association of Urology–Young Academic Urologists Sexual and Reproductive Working Group. Patients' attitude with surgery for Peyronie's disease: results from a multicentric European study. J Sex Med. 2023 Nov 16:qdad145. doi: 10.1093/jsxmed/qdad145. Epub ahead of print. PMID: 37973410.

Lee WG, Gordon P, Ralph D. Lightweight macroporous mesh can be used for corporal reconstruction during penile prosthesis surgery. J Sex Med. 2023 Nov 30;20(12):1446-1450. doi: 10.1093/jsxmed/qdad134. PMID: 37818830.

Almsaoud NA, Safar O, Alshahrani ST, Alwadai R, Alkhaldi SM, Almurayyi M, Alrweili HH, Assiri HM, Al Jubran A, Hakami B, Alzahrani MA. The effect of penile traction device in men with Peyronie's disease on penile curvature, penile length, and erectile dysfunction: a systematic review and meta-analysis. Transl Androl Urol. 2023 Nov 30;12(11):1673-1685. doi: 10.21037/tau-23-310. Epub 2023 Nov 9. PMID: 38106680; PMCID: PMC10719764.

Kianian R, Andino JJ, Morrison JJ, Grundy D, Appleton A, Lavold AJ, Eleswarapu SV, Mills JN. Potential primary prevention of Peyronie's disease post prostatectomy?-retrospective analysis of peri-operative multi-modal penile rehabilitation. Transl Androl Urol. 2023 Nov 30;12(11):1708-1712. doi: 10.21037/tau-23-281. Epub 2023 Nov 23. PMID: 38106686; PMCID: PMC10719776.
27 y. o. Peyronies since 2020: S curvature with the top part tilting to the left - 15*. Multiple nodules and scarring on each side, mild hourglassing. Getting worse every few months, losing width. Normal penile function. Enlarged veins.

bentoboy

December

Pinkhasov AM, Beamer M, Shulman D, Yakubov R, Pinkhasov E, Kravchick S. A novel technique for unilateral dissection of the penile neurovascular bundle to prevent loss of penile sensation during treatment of Peyronie's disease-Initial results of a pilot study. Curr Urol. 2023 Dec;17(4):299-302. doi: 10.1097/CU9.0000000000000209. Epub 2023 Jun 8. PMID: 37994333; PMCID: PMC10662816.

Larson H, Warner J, Savage J, Kohler T, Ziegelmann M, Trost L. Changes in Point of Maximal Curvature During Collagenase Clostridium Histolyticum Injections for Peyronie's Disease. Urology. 2023 Dec 5:S0090-4295(23)01018-X. doi: 10.1016/j.urology.2023.11.024. Epub ahead of print. PMID: 38061610.

Langbo WA, Wang V, Bajic P, Levine L. Long-term outcomes after plaque excision grafting for Peyronie's disease and subanalysis of patients who undergo the procedure despite preoperative counseling against it. J Sex Med. 2023 Dec 12:qdad164. doi: 10.1093/jsxmed/qdad164. Epub ahead of print. PMID: 38087916.

Karakose A, Yitgin Y. A new alternative approach to management of acute phase Peyronie's disease: low intensity extracorporeal shockwave therapy and platelet-rich plasma. Minerva Urol Nephrol. 2023 Dec 13. doi: 10.23736/S2724-6051.23.05458-7. Epub ahead of print. PMID: 38093617.

Alzahrani MA. Penile Mondor's Disease Resulting From Forceful Condom Removal During Sexual Intercourse: A Case Report and Literature Review. Cureus. 2023 Dec 20;15(12):e50872. doi: 10.7759/cureus.50872. PMID: 38130908; PMCID: PMC10733711.

Larson H, Savage J, Brearton K, Warner R, Ziegelmann M, Kohler T, Trost L. Outcomes of collagenase Clostridium histolyticum in men with ventral curvatures: an updated series. J Sex Med. 2023 Dec 22:qdad167. doi: 10.1093/jsxmed/qdad167. Epub ahead of print. PMID: 38141054.
 
27 y. o. Peyronies since 2020: S curvature with the top part tilting to the left - 15*. Multiple nodules and scarring on each side, mild hourglassing. Getting worse every few months, losing width. Normal penile function. Enlarged veins.

bentoboy

January


Falcone M, Preto M, Morgado AR, Sokolakis I, Sarıkaya S, Capece M, Capogrosso P, Manfredi C, Tsampoukas G, Russo G. Risk and benefits of penile length preservation techniques during penile prosthesis implantation: a systematic review by the young academic urologists sexual and reproductive health working group. Ther Adv Urol. 2024 Jan 8;16:17562872231215177. doi: 10.1177/17562872231215177. PMID: 38205393; PMCID: PMC10775725.

Natsos A, Tatanis V, Kontogiannis S, Waisbrod S, Gkeka K, Obaidad M, Peteinaris A, Pagonis K, Papadopoulos C, Kallidonis P, Liatsikos E, Drettas P. Grafts in Peyronie's surgery without the use of prostheses: a systematic review and meta-analysis. Asian J Androl. 2024 Jan 9. doi: 10.4103/aja202358. Epub ahead of print. PMID: 38265253.

Durukan E, Kraglund R, Rashid SA, Thorkilgaard T, Jensen CFS, Fode M. Phosphodiesterase type 5 inhibitors do not prevent curvature progression but shorten pain duration in the active phase of Peyronie's Disease: A retrospective cohort study. Int J Impot Res. 2024 Jan 16. doi: 10.1038/s41443-023-00810-5. Epub ahead of print. PMID: 38228873.

Dell'Atti L, Slyusar V, Ronchi P. Serum Testosterone Concentration Influences the Response to Extracorporeal Shock Wave Treatment in Men With Peyronie's Disease. Urology. 2024 Jan;183:111-116. doi: 10.1016/j.urology.2023.09.037. Epub 2023 Oct 11. PMID: 37832829.

Langbo WA, Wang V, Bajic P, Levine L. Long-term outcomes after plaque excision grafting for Peyronie's disease and subanalysis of patients who undergo the procedure despite preoperative counseling against it. J Sex Med. 2024 Jan 30;21(2):163-168. doi: 10.1093/jsxmed/qdad164. PMID: 38087916.

Zucker I, Nackeeran S, Mirza S, Masterson TA. Risk Factors for Penile Fracture After Intralesional Collagenase Clostridium histolyticum in Peyronie's Disease. Urology. 2024 Jan;183:117-120. doi: 10.1016/j.urology.2023.10.019. Epub 2023 Nov 8. PMID: 37949243.

Paulis G, Paulis A, De Giorgio G, Quattrocchi S. Measurement of Oxidative Stress Index (OSI) in Penile Corpora Cavernosa and Peripheral Blood of Peyronie's Disease Patients: A Report of 49 Cases. Metabolites. 2024 Jan 15;14(1):55. doi: 10.3390/metabo14010055. PMID: 38248858; PMCID: PMC10821449.

Giagulli VA, Lisco G, De Tullio A, Guastamacchia E, Triggiani V, Jirillo E. The pathogenic role of the immune system in erectile dysfunction and Peyronie's disease: focusing on immunopathophysiology and potential therapeutic strategies. Sex Med Rev. 2024 Jan 9:qead055. doi: 10.1093/sxmrev/qead055. Epub ahead of print. PMID: 38196188.

Podlasek CA. Nanotechnology in sexual medicine. J Sex Med. 2024 Jan 30;21(2):81-83. doi: 10.1093/jsxmed/qdad149. PMID: 38314625; PMCID: PMC10839571.

Cilio S, Rocca R, Celentano G, Marino C, Creta M, Califano G, Manfredi C, Russo GI, Morgado A, Falcone M, Capece M; YAU Working Group Sexual and Reproductive Health. Intraplaque injections of hyaluronic acid for the treatment of stable-phase Peyronie's disease: a retrospective single-center experience. Asian J Androl. 2024 Feb 2. doi: 10.4103/aja202371. Epub ahead of print. PMID: 38305689.

Moraes Braga C, Cantilino A. An unwelcome third party: the role of inflammation in the relationship between depression and Peyronie's disease. Sex Med Rev. 2024 Feb 1:qeae002. doi: 10.1093/sxmrev/qeae002. Epub ahead of print. PMID: 38303665.

Twidwell J, Mahon J, Tortorelis D, Levine L. Transdermal application of H100 gel to the penile shaft in patients with Peyronie's disease infiltrates the tunica albuginea. Int J Impot Res. 2024 Jan 13. doi: 10.1038/s41443-023-00819-w. Epub ahead of print. PMID: 38218956.



 
27 y. o. Peyronies since 2020: S curvature with the top part tilting to the left - 15*. Multiple nodules and scarring on each side, mild hourglassing. Getting worse every few months, losing width. Normal penile function. Enlarged veins.

bentoboy

February

Larson H, Warner J, Savage J, Kohler T, Ziegelmann M, Trost L. Changes in Point of Maximal Curvature During Collagenase Clostridium Histolyticum Injections for Peyronie's Disease. Urology. 2024 Feb;184:122-127. doi: 10.1016/j.urology.2023.11.024. Epub 2023 Dec 6. PMID: 38061610.


Cilio S, Rocca R, Celentano G, Marino C, Creta M, Califano G, Manfredi C, Russo GI, Morgado A, Falcone M, Capece M; YAU Working Group Sexual and Reproductive Health. Intraplaque injections of hyaluronic acid for the treatment of stable-phase Peyronie's disease: a retrospective single-center experience. Asian J Androl. 2024 Feb 2. doi: 10.4103/aja202371. Epub ahead of print. PMID: 38305689.


Wang X, Bao X, Liu H, Cui Y. Exploring the pharmacological mechanism of Herba Epimedii (yinyanghuo) for Peyronie's disease with network pharmacology strategy. Asian J Surg. 2024 Feb 20:S1015-9584(24)00270-7. doi: 10.1016/j.asjsur.2024.02.012. Epub ahead of print. PMID: 38383197.

Garaffa G, Traunero F, Claps F, Pavan N, Rossin G, Piasentin A, Rizzo M, Biasatti A, Zorzi F, Trombetta C, Liguori G, Ongaro L. Plication surgery does not produce additional loss of length in Peyronie's disease patients. Int J Impot Res. 2024 Feb 22. doi: 10.1038/s41443-024-00852-3. Epub ahead of print. PMID: 38388784.

Levine LA, Desouky E, Elist JJ, Moon D, Wilson SK. Use of Himplant® for correction of residual deformity following prior treatment of peyronie's disease: a case series. Int J Impot Res. 2024 Feb 23. doi: 10.1038/s41443-024-00840-7. Epub ahead of print. PMID: 38388785.

Ledesma BR, Velasquez DA, Egemba C, Molina M, Ibrahim E, Costantini-Mesquita F, Deebel NA, Han S, Reis IM, Saltzman R, Ramasamy R. A phase 2 randomized, placebo-controlled crossover trial to evaluate safety and efficacy of platelet-rich plasma injections for Peyronie's disease: clinical trial update. Int J Impot Res. 2024 Feb 29. doi: 10.1038/s41443-024-00844-3. Epub ahead of print. PMID: 38424354.


March

Thach S, Pommier B, Soulier V. The impact of Peyronie's disease on couples. Fr J Urol. 2024 Mar 4;34(4):102595. doi: 10.1016/j.fjurol.2024.102595. Epub ahead of print. PMID: 38442548.

Rassweiler JJ, Scheitlin W, Goezen AS, Radecke F. Long-term experiences with high-energy shock wave therapy in the management chronic phase Peyronie's disease using two different electromagnetic lithotripters. World J Urol. 2024 Mar 7;42(1):124. doi: 10.1007/s00345-024-04792-x. PMID: 38453751; PMCID: PMC10920406.

Şahin A, Babayev H, Cirigliano L, Preto M, Falcone M, Altıntas E, Gül M. Unveiling the molecular Hallmarks of Peyronie's disease: a comprehensive narrative review. Int J Impot Res. 2024 Mar 7. doi: 10.1038/s41443-024-00845-2. Epub ahead of print. PMID: 38454161.

Institute for Quality and Efficiency in Health Care (IQWiG). Penile traction therapy for induratio penis plastica: IQWiG Reports – Commission No. N22-01 [Internet]. Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2024 Mar 8. PMID: 38574187.

Hatzichristodoulou G, Gültekin MH, Özkara H, Akkus E. First worldwide correction of ventral Peyronie's disease utilizing rigicon inflatable penile prosthesis combined with plaque incision & grafting with collagen fleece (PICS-technique) for residual curvature. Int J Impot Res. 2024 Mar 13. doi: 10.1038/s41443-024-00873-y. Epub ahead of print. PMID: 38480871.

Jin DC, Luo Y, Wang P, Zhang Y, Bi G, Tong DL, Wang YY, Zhou WY, Li YF. Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease. J Vis Exp. 2024 Mar 15;(205). doi: 10.3791/66305. PMID: 38557978.

Paulis G, De Giorgio G, Paulis A. Ultrasound Elastography as a Diagnostic Tool for Peyronie's Disease: A State-of-the-Art Review. Diagnostics (Basel). 2024 Mar 21;14(6):665. doi: 10.3390/diagnostics14060665. PMID: 38535085; PMCID: PMC10969672.

Giagulli VA, Lisco G, De Tullio A, Guastamacchia E, Triggiani V, Jirillo E. The pathogenic role of the immune system in erectile dysfunction and Peyronie's disease: focusing on immunopathophysiology and potential therapeutic strategies. Sex Med Rev. 2024 Mar 26;12(2):210-220. doi: 10.1093/sxmrev/qead055. PMID: 38196188.

"This study is to our knowledge the first analysis of temporal gene expression associated with the regulation of the transformation of resident fibroblasts to profibrotic myofibroblasts in Peyronies Disease. Further research is warranted to investigate the role of the MAPK-Hedgehog signaling pathways in reversibility of Peyronies Disease.'

Spirito L, Manfredi C, La Rocca R, Napolitano L, Di Girolamo A, Capece M, Trama F, Sciorio C, Sokolakis I, Creta M, Arcaniolo D. Daily low-dose tadalafil may reduce the penile curvature progression rate in patients with acute Peyronie's disease: a retrospective comparative analysis. Int J Impot Res. 2024 Apr;36(2):129-134. doi: 10.1038/s41443-022-00651-8. Epub 2022 Dec 13. PMID: 36513814.
27 y. o. Peyronies since 2020: S curvature with the top part tilting to the left - 15*. Multiple nodules and scarring on each side, mild hourglassing. Getting worse every few months, losing width. Normal penile function. Enlarged veins.

bentoboy

April

Spirito L, Manfredi C, La Rocca R, Napolitano L, Preto M, Di Girolamo A, Arcaniolo D, De Sio M, Creta M, Longo N. Long-term outcomes of extracorporeal shock wave therapy for acute Peyronie's disease: a 10-year retrospective analysis. Int J Impot Res. 2024 Apr;36(2):135-139. doi: 10.1038/s41443-023-00673-w. Epub 2023 Feb 14. PMID: 36788352.

Maremanda AP, Du Comb W, Able C, Kohn TP, Unal S, Burnett AL. Erectile dysfunction and Peyronie's disease diagnosis rates after penile fracture-a retrospective claims database cohort analysis. Int J Impot Res. 2024 Apr;36(2):125-128. doi: 10.1038/s41443-023-00746-w. Epub 2023 Aug 4. PMID: 37542153.

Zugail AS, Alshuaibi M, Lombion S, Beley S. Safety and feasibility of percutaneous needle tunneling with platelet-rich plasma injections for Peyronie's disease in the outpatient setting: a pilot study. Int J Impot Res. 2024 Apr;36(2):140-145. doi: 10.1038/s41443-023-00744-y. Epub 2023 Aug 7. PMID: 37550385.

Loloi J, Schuppe K, Reddy RV, Rahman F, Bernstein A, Reddy P, Kulkarni N, Masterson T, Ramasamy R. A survey of exposure to the use of Xiaflex for the treatment of Peyronie's disease among United States urology residency programs. Int J Impot Res. 2024 Apr;36(2):155-159. doi: 10.1038/s41443-023-00781-7. Epub 2023 Oct 21. PMID: 37865716.

Kadıoğlu A, Gürcan M, Rakhmonovich AF, Dursun M. Surgical management of complex curvature in Peyronie's disease. World J Urol. 2024 Apr 30;42(1):276. doi: 10.1007/s00345-024-04936-z. PMID: 38689034; PMCID: PMC11061042.

Schneider D, O'Leary M, Amini E, Miller J, Hassas N, Nguyen J, Hammad MAM, Barham D, Yafi FA. Peyronie's disease response to intralesional collagenase clostridium histolyticum therapy is independent of baseline testosterone. Andrology. 2024 May;12(4):830-834. doi: 10.1111/andr.13532. Epub 2023 Sep 27. PMID: 37753943.
27 y. o. Peyronies since 2020: S curvature with the top part tilting to the left - 15*. Multiple nodules and scarring on each side, mild hourglassing. Getting worse every few months, losing width. Normal penile function. Enlarged veins.

bentoboy

April

Spinozzi L, Droghetti M, Palmisano F, Piazza P, Fontanella L, Gentile G, Franceschelli A, Colombo F. Use of Soft Penile Prosthesis in Grafting Surgery for Peyronie's Disease and Mild Erectile Dysfunction: Still an Option? Arch Esp Urol. 2024 Apr;77(3):270-277. doi: 10.56434/j.arch.esp.urol.20247703.36. PMID: 38715168.


Roadman D, Feng C, Salkowski M, Levine LA. A contemporary systematic review of penile lengthening procedures with penile prosthesis. Transl Androl Urol. 2024 Apr 30;13(4):596-612. doi: 10.21037/tau-23-354. Epub 2024 Apr 18. PMID: 38721300; PMCID: PMC11074682.

May

Cosentino M, Di Nauta M, Boeri L, Ferraioli G, Lucignani G, Ricapito A, Gadda F, Iafrate M, Mancini M, Dal Moro F, Ruiz-Castañe E, Bettocchi C, Montanari E, Sofikitis N. Conservative treatment of Peyronie's disease: a guide. World J Urol. 2024 May 13;42(1):317. doi: 10.1007/s00345-024-04975-6. PMID: 38740620.

Tienforti D, Hoxha M, Di Pasquale AB, Rizza V, Barbonetti A. Analysis of evidence on nutraceutical interventions for Peyronie's disease: a guideline-based critical review. Sex Med Rev. 2024 May 28:qeae038. doi: 10.1093/sxmrev/qeae038. Epub ahead of print. PMID: 38807529.


Asmundo MG, Durukan E, von Rohden E, Thy SA, Jensen CFS, Fode M. Platelet-rich plasma therapy in erectile dysfunction and Peyronie's disease: a systematic review of the literature. World J Urol. 2024 May 29;42(1):359. doi: 10.1007/s00345-024-05065-3. PMID: 38811395; PMCID: PMC11136842.


Ilg MM, Bustin SA, Ralph DJ, Cellek S. TGF-β1 induces formation of TSG-6-enriched extracellular vesicles in fibroblasts which can prevent myofibroblast transformation by modulating Erk1/2 phosphorylation. Sci Rep. 2024 May 29;14(1):12389. doi: 10.1038/s41598-024-62123-x. PMID: 38811625; PMCID: PMC11136978.


Kolanukuduru KP, Mandel AL, Simhal RK, Sholklapper TN, Sun K, Poluch M, Wang KR, Shah YB, Chung PH. Marfan's syndrome is associated with a greater risk of Peyronie's disease: a case-control study of the TriNetX database. Int J Impot Res. 2024 May 30. doi: 10.1038/s41443-024-00923-5. Epub ahead of print.PMID: 38816576.


Ceballos B, Baumgarten AS, Krug AM, Morey AF. Extratunical grafting for minimally invasive management of complex Peyronie's disease deformities. J Sex Med. 2024 May 28;21(6):579-581. doi: 10.1093/jsxmed/qdae049. PMID: 38825575.


Wang W, Wan F, Yu T, Wu S, Cui X, Xiang C, Li M, Liu Q, Lin C. Microvesicles-delivering Smad7 have advantages over microvesicles in suppressing fibroblast differentiation in a model of Peyronie's disease. BMC Biotechnol. 2024 Jun 7;24(1):40. doi: 10.1186/s12896-024-00866-1. PMID: 38849776; PMCID: PMC11162046.


Dell'Atti L, Slyusar V, Cambise C. Multimodal treatments based on Tadalafil during acute phase of Peyronie's disease: experience at two referral academic centers. Ir J Med Sci. 2024 Jun 11. doi: 10.1007/s11845-024-03734-1. Epub ahead of print. PMID: 38861101.
27 y. o. Peyronies since 2020: S curvature with the top part tilting to the left - 15*. Multiple nodules and scarring on each side, mild hourglassing. Getting worse every few months, losing width. Normal penile function. Enlarged veins.