Peyronies articles: review

[bentoboy]

Hi there,

I would like to create a list of all (or at least of the most relevant ones) academic articles/expected clinical studies/news articles etc. published in the recent years on Peyronies.

I do not know about you but for me it is super useful to have a list of all articles that have been published recently and then update it every month - just to keep track of all developments in the area.

Important Clinical trials:

• Stem Cell Treatment of Peyronie´s Disease (Denmark):
� posted: 25 February 2021; 22 participants
� expected completion: May 30, 2024
� link

• PRP for treatment of Peyronies (US):
� posted: August 23, 2020; 80 participants; randomised
� expected completion: April 1, 2024
� link

Academic articles – 2023

• January 2023:

Yang CH, Lin DY, Lin YS, Hsu CY, Tung MC, Tan KT, Ou YC. The Immunological Microenvironment and the Emerging Role of Stem Cells Therapy in Peyronie's Disease: A Systematic Narrative Review. Int J Mol Sci. 2023 Jan 1;24(1):777. doi: 10.3390/ijms24010777. PMID: 36614220; PMCID: PMC9821411.

• February 2023:

Reddy AG, Dai MC, Song JJ, Pierce HM, Patel SR, Lipshultz LI. Peyronie's Disease: An Outcomes-Based Guide to Non-Surgical and Novel Treatment Modalities. Res Rep Urol. 2023 Feb 2;15:55-67. doi: 10.2147/RRU.S278796. PMID: 36756281; PMCID: PMC9901485.

Kulkarni Y, Green B, Pattillo C, Stirland I, Flores A, Ziegelmann M, Kohler T, Helo S, Trost L. Efficacy of collagenase Clostridium histolyticum in men with congenital penile curvature. J Sex Med. 2023 Feb 14;20(2):194-199. doi: 10.1093/jsxmed/qdac006. PMID: 36763911.

Li MK, Sigalos JT, Yoffe DA, Modiri N, Hu MY, Gaither TW, Santamaria A, Walker DT, Regets KV, Mills JN, Eleswarapu SV. Multiple courses of intralesional collagenase injections for Peyronie disease: a retrospective analysis. J Sex Med. 2023 Feb 14;20(2):200-204. doi: 10.1093/jsxmed/qdac030. PMID: 36763912.

Falcone M, Preto M, Peretti F, Gontero P, Pyrgidis N, Sokolakis I, Hatzichristodoulou G. The use of collagen fleece to correct residual curvature during inflatable penile prosthesis implantation (PICS technique) in patients with complex Peyronie disease: a multicenter study. J Sex Med. 2023 Feb 14;20(2):229-235. doi: 10.1093/jsxmed/qdac003. PMID: 36763916.

Searl T, Ohlander S, McVary KT, Podlasek CA. Pathway analysis of microarray data from corpora cavernosal tissue of patients with a prostatectomy or Peyronie disease in comparison with a cavernous nerve-injured rat model of erectile dysfunction. J Sex Med. 2023 Feb 14;20(2):139-151. doi: 10.1093/jsxmed/qdac019. PMID: 36763930.

Gundogdu G, Nguyen T, Namasivayam A, Starek S, Gelman J, Mauney JR. Characterization of a novel rabbit model of Peyronie's disease. Int J Impot Res. 2023 Feb 13. doi: 10.1038/s41443-023-00671-y. Epub ahead of print. PMID: 36782023.

Spirito L, Manfredi C, La Rocca R, Napolitano L, Preto M, Di Girolamo A, Arcaniolo D, De Sio M, Creta M, Longo N. Long-term outcomes of extracorporeal shock wave therapy for acute Peyronie's disease: a 10-year retrospective analysis. Int J Impot Res. 2023 Feb 14. doi: 10.1038/s41443-023-00673-w. Epub ahead of print. PMID: 36788352.

Sicignano E, Imperatore V, Sciorio C, Di Girolamo A. The clinical potential of flavonoids in Peyronie's disease. J Basic Clin Physiol Pharmacol. 2023 Feb 15;34(2):121-123. doi: 10.1515/jbcpp-2023-0006. PMID: 36790332.

Vieiralves RR, Schuh MF, Favorito LA. Low-intensity extracorporeal shockwave therapy in the treatment of erectile dysfunction - a narrative review. Int Braz J Urol. 2023 Feb 15;49. doi: 10.1590/S1677-5538.IBJU.2023.9904. Epub ahead of print. PMID: 36794846.

Bole R, Alom M, Habashy E, Ahmed M, Ziegelmann M, Kohler T, Helo S. The clinical significance of imperfection: is idiopathic corporal asymmetry related to curvature during penile prosthesis placement? Int J Impot Res. 2023 Feb 16. doi: 10.1038/s41443-023-00669-6. Epub ahead of print. PMID: 36797455.

Kothiya AB, Adlakha N. Cellular nitric oxide synthesis is affected by disorders in the interdependent [Formula: see text] and [Formula: see text] dynamics during cystic fibrosis disease. J Biol Phys. 2023 Feb 22. doi: 10.1007/s10867-022-09624-w. Epub ahead of print. PMID: 36811722.

Brant A, Basourakos SP, Lewicki P, Kang C, Marinaro J, Punjani N, Kashanian JA. Real-world practice in Peyronie's disease management: Results from a national survey of urologists. Andrology. 2023 Feb 23. doi: 10.1111/andr.13414. Epub ahead of print. PMID: 36815582.

Schifano N, Capogrosso P, Antonini G, Baldini S, Scroppo F, Salonia A, Zerbinati N, Dehò F. The Application of Hyaluronic Acid Injections in Functional and Aesthetic Andrology: A Narrative Review. Gels. 2023 Feb 1;9(2):118. doi: 10.3390/gels9020118. PMID: 36826290; PMCID: PMC9957416.

Ziegelmann M. Is there a new role for oral therapy to treat peyronie's disease? Commentary on Daily low-dose tadalafil may reduce the penile curvature progression rate in patients with acute Peyronie's Disease: a retrospective comparative analysis. Int J Impot Res. 2023 Feb 24. doi: 10.1038/s41443-023-00684-7. Epub ahead of print. PMID: 36828955.


• March 2023:

Levine LA. What's the new thing for surgical treatment of Peyronie's disease? Extratunical grafting. J Sex Med. 2023 Mar 31;20(4):416-417. doi: 10.1093/jsxmed/qdac039. PMID: 36763947.

Ziegelmann M, Hu Y, Xiang Q, Liu G, McLane MP, Trost L. Incremental Treatment Response by Cycle With Collagenase Clostridium Histolyticum for Peyronie's Disease: A Pooled Analysis of Two Phase 3 Trials. Urology. 2023 Mar 1:S0090-4295(23)00182-6. doi: 10.1016/j.urology.2023.02.019. Epub ahead of print. PMID: 36863600.

Paulis G, Paulis A, Perletti G. Congenital penile curvature as a possible risk factor for the onset of Peyronie's disease, and psychological consequences of penile curvature. Arch Ital Urol Androl. 2023 Mar 15;95(1). doi: 10.4081/aiua.2023.11238. PMID: 36924365.

Pakpahan C, Ilhamsyah I, Supardi S, Narulita P, Agustinus A, Darmadi D. The interplay between neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, erectile dysfunction, and Peyronie's disease: A meta-analysis of observational studies. Arch Ital Urol Androl. 2023 Mar 15;95(1). doi: 10.4081/aiua.2023.11162. PMID: 36924369.

• April 2023:

Conlon WJ, Herzog BJ, Hellstrom WJG. Residual penile curvature correction by modeling during penile prosthesis implantation in Peyronie's disease patients. Int J Impot Res. 2023 Apr 13. doi: 10.1038/s41443-023-00694-5. Epub ahead of print. PMID: 37055523.

Chung E, Moon DG, Hui J, Chang HC, Hakim L, Nagao K, Tan R, Mak SK, Tantiwongse K, Lin H, Mai DBT, Nguyen Q, Tan HM, Sato Y, Jiann BP, Park K, Xin ZC, Park HJ. Clinical recommendations on penile reconstructive and prosthetic surgery: a consensus statement from the Asia-Pacific Society of Sexual Medicine. Sex Med. 2023 Apr 11;11(2):qfad003. doi: 10.1093/sexmed/qfad003. PMID: 37056790; PMCID: PMC10086569.

Thomas J, Sencaj M, Ghomeshi A, Zucker IJ, Best JC, Ramasamy R. Stem-Cell, Shockwave, and Platelet Rich Plasma Therapy for the Treatment of Erectile Dysfunction and Peyronie's Disease: A Survey of Clinics Across the US. Urology. 2023 Apr 17:S0090-4295(23)00323-0. doi: 10.1016/j.urology.2023.01.061. Epub ahead of print. PMID: 37076023.

Feng CL, Langbo WA, Anderson LK, Cao D, Bajic P, Amarasekera C, Wang V, Levine LA. Subcoronal inflatable penile prosthesis implantation: indications and outcomes. J Sex Med. 2023 Apr 19:qdad049. doi: 10.1093/jsxmed/qdad049. Epub ahead of print. PMID: 37076135.

Ilg MM, Ralph DJ, Cellek S. Statins synergize with phosphodiesterase type 5 inhibitors but not with selective estrogen receptor modulators to prevent myofibroblast transformation in an in vitro model of Peyronie's disease. J Sex Med. 2023 Apr 20:qdad051. doi: 10.1093/jsxmed/qdad051. Epub ahead of print. PMID: 37082866.

News articles:

January 2023:

• Scientists Reverse Erectile Dysfunction in Pigs Using Synthetic Tissue Link

February 2023:

• Endo Launches "Man With a Plan" Campaign to Support Men With Symptoms of Peyronie's Disease Link

April  2023:

• Early-onset diabetes appears to affect Peyronie disease severity  Link

[FrankPD]

It's nice to know there's that many studies.  If felt nearly nonexistent to me even after being 16 months since diagnosis.  Most don't even know this exists. 

Thanks!

[bentoboy]

Not many new articles for May. Here you go anyway:

May 2023

Paulis G, Paulis A. Chronic prostatitis as possible risk factor for Peyronie's disease: Psychological, sexual and prostatitis-like symptoms in patients with Peyronies Disease. Arch Ital Urol Androl. 2023 May 31:11406. doi: 10.4081/aiua.2023.11406. Epub ahead of print. PMID: 37259816.

Henry AJ, Holler JT, Lui J, Breyer BN, Ziegelmann M, Cohen T, Smith RP, Yeaman C, Winkelman AJ, Villanueva C, Kern NG. Do patients with Peyronie's disease perceive penile curvature in adults and children differently than the general population? J Sex Med. 2023 Jun 2:qdad073. doi: 10.1093/jsxmed/qdad073. Epub ahead of print. PMID: 37279444.

[bentoboy]

June 2023

Wilson SK, Wen L, Rossello M, Maria P, Carrion R, Perito P, Ralph D, Antonini G, Carvajal A, Ozturk MI, Chung E. Initial safety outcomes for the Rigicon Infla10® inflatable penile prosthesis. BJU Int. 2023 Jun;131(6):729-733. doi: 10.1111/bju.15960. Epub 2023 Mar 6. PMID: 36633050.

Kothiya AB, Adlakha N. Cellular nitric oxide synthesis is affected by disorders in the interdependent [Formula: see text] and [Formula: see text] dynamics during cystic fibrosis disease. J Biol Phys. 2023 Jun;49(2):133-158. doi: 10.1007/s10867-022-09624-w. Epub 2023 Feb 22. PMID: 36811722; PMCID: PMC10160313.

Mitsui Y, Yamabe F, Hori S, Uetani M, Kobayashi H, Nagao K, Nakajima K. Molecular Mechanisms and Risk Factors Related to the Pathogenesis of Peyronie's Disease. Int J Mol Sci. 2023 Jun 14;24(12):10133. doi: 10.3390/ijms241210133. PMID: 37373277; PMCID: PMC10299070.

Lee HY, Pyun JH, Shim SR, Kim JH. Medical Treatment for Peyronie's Disease: Systematic Review and Network Bayesian Meta-Analysis. World J Mens Health. 2023 Jun 15. doi: 10.5534/wjmh.230016. Epub ahead of print. PMID: 37382281.

Khooblall P, Bole R, Lundy SD, Bajic P. Expanded Utilization of Intralesional Therapies for Treatment of Peyronie's Disease. Res Rep Urol. 2023 Jun 21;15:205-216. doi: 10.2147/RRU.S386340. PMID: 37366388; PMCID: PMC10290860.

Ilg MM, Ralph DJ, Cellek S. Statins synergize with phosphodiesterase type 5 inhibitors but not with selective estrogen receptor modulators to prevent myofibroblast transformation in an in vitro model of Peyronie's disease. J Sex Med. 2023 Jun 28;20(7):925-934. doi: 10.1093/jsxmed/qdad051. PMID: 37082866.

Henry AJ, Holler JT, Lui J, Breyer BN, Ziegelmann M, Cohen T, Smith RP, Yeaman C, Winkelman AJ, Villanueva C, Kern NG. Do patients with Peyronie's disease perceive penile curvature in adults and children differently than the general population? J Sex Med. 2023 Jun 28;20(7):998-1003. doi: 10.1093/jsxmed/qdad073. PMID: 37279444.

Bole R, Bajic P. Editorial CommentRe: Stem-Cell, Shockwave, and Platelet Rich Plasma Therapy for the Treatment of Erectile Dysfunction and Peyronie's Disease: A Survey of Clinics Across the USA. Urology. 2023 Jun 30:S0090-4295(23)00325-4. doi: 10.1016/j.urology.2023.01.062. Epub ahead of print. PMID: 37394358.

July 2023

Roadman D, Wang V, Langbo W, Paddock D, Levine L. Predictors of hinge effect in patients with Peyronie's disease. J Sex Med. 2023 Jul 17:qdad087. doi: 10.1093/jsxmed/qdad087. Epub ahead of print. PMID: 37460401.

Rosenberg JE, Ergun O, Hwang EC, Risk MC, Jung JH, Edwards ME, Blair Y, Dahm P. Non-surgical therapies for Peyronie's disease. Cochrane Database Syst Rev. 2023 Jul 17;7(7):CD012206. doi: 10.1002/14651858.CD012206.pub2. PMID: 37490423; PMCID: PMC10351344.

Roadman D, Wang V, Beer A, Levine L. A contemporary assessment of the evaluation and management of patients presenting to a tertiary medical center with Peyronie's disease. Int J Impot Res. 2023 Jul 19. doi: 10.1038/s41443-023-00738-w. Epub ahead of print. PMID: 37468535.

Rahardjo HE, Märker V, Tsikas D, Kuczyk MA, Ückert S, Bannowsky A. Fibrotic Diseases of the Human Urinary and Genital Tract: Current Understanding and Potential Strategies for Treatment. J Clin Med. 2023 Jul 19;12(14):4770. doi: 10.3390/jcm12144770. PMID: 37510885; PMCID: PMC10381287.

Osman MM, Hammad MA, Barham DW, Toma R, El-Khatib FM, Dianatnejad S, Nguyen J, Towe M, Choi E, Wu Q, Banavar G, Cai Y, Moura P, Shen N, Vuyisich M, Yafi NR, Yafi FA. Comparison of the gut microbiome composition between men with Peyronie's disease and a matched cohort: a pilot study. Int J Impot Res. 2023 Jul 20. doi: 10.1038/s41443-023-00737-x. Epub ahead of print. PMID: 37474796.

Dell'Atti L, Ronchi P. Low-intensity laser diode plus extracorporeal shock wave therapy: a new treatment strategy in the management of Peyronie's disease. World J Urol. 2023 Jul 25. doi: 10.1007/s00345-023-04533-6. Epub ahead of print. PMID: 37490060.

Park SH, Wilson SK, Wen L. Subcoronal Incision for Inflatable Penile Prosthesis Does Not Risk Glans Necrosis. J Urol. 2023 Jul 25:101097JU0000000000003619. doi: 10.1097/JU.0000000000003619. Epub ahead of print. PMID: 37490615.

August 2023

Schifano N, Capogrosso P, Boeri L, Fallara G, Chiappini S, Rewhorn M, Cakir OO, Harvey H, Castiglione F, Alnajjar HM, Muneer A, Deho' F, Schifano F, Montorsi F, Salonia A. Are finasteride-related penile curvature/Peyronie's disease Adverse Event Reports worthy of further clinical investigation? Disproportionality analysis based on both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) pharmacovigilance databases. Int J Impot Res. 2023 Aug;35(5):465-471. doi: 10.1038/s41443-022-00568-2. Epub 2022 May 5. PMID: 35513712.