HDAC Inhibitor Vorinostat to treat and cure penile fibrosis including Peyronie's

[Izan82]

Hello,

I'm new to this forum. Has anyone of you tried the powerful HDAC inhibitor Vorinostat to clear penile fibrosis by normalizing the HDAC/TGF-β pathway?

https://pubmed.ncbi.nlm.nih.gov/33064925/

https://pubmed.ncbi.nlm.nih.gov/35023296/

https://pubmed.ncbi.nlm.nih.gov/29631978/

A person weighing 80 kg should take 200 mg Vorinostat for at least 14 days and preferably 30 days.

Please let me know what you think.

[Bud luck]

I see that they are injections, injections on my penis tend to cause more problems.

[Izan82]

No, Vorinostat was given orally.


https://pubmed.ncbi.nlm.nih.gov/35023296/

"CNCI treated with daily oral administration of 25.0 mg/kg HDACi."

[Bud luck]

Great, do you know how to get it?

[Bud luck]

The study is on rats, I wonder if is been tested on men with penis fibrosis.