HDAC Inhibitor Vorinostat to treat and cure penile fibrosis including Peyronie's

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Izan82

Hello,

I'm new to this forum. Has anyone of you tried the powerful HDAC inhibitor Vorinostat to clear penile fibrosis by normalizing the HDAC/TGF-β pathway?

https://pubmed.ncbi.nlm.nih.gov/33064925/

https://pubmed.ncbi.nlm.nih.gov/35023296/

https://pubmed.ncbi.nlm.nih.gov/29631978/

A person weighing 80 kg should take 200 mg Vorinostat for at least 14 days and preferably 30 days.

Please let me know what you think.

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Bud luck

I see that they are injections, injections on my penis tend to cause more problems.
My first symptoms started early in 2019
I tried Traction device, Pentofixiline, Q10, TRT, L-Argenine, cialis
I have narrowing/dent/hinge on the left side of my shaft
My ED is getting worse
Had a PRP shot Aug 2021
I have a girlfriend
Age 46

Izan82

No, Vorinostat was given orally.


https://pubmed.ncbi.nlm.nih.gov/35023296/

"CNCI treated with daily oral administration of 25.0 mg/kg HDACi."
If you want answers, Please help us by filling in your signature block

Click here for Directions

Bud luck

My first symptoms started early in 2019
I tried Traction device, Pentofixiline, Q10, TRT, L-Argenine, cialis
I have narrowing/dent/hinge on the left side of my shaft
My ED is getting worse
Had a PRP shot Aug 2021
I have a girlfriend
Age 46

Bud luck

The study is on rats, I wonder if is been tested on men with penis fibrosis.
My first symptoms started early in 2019
I tried Traction device, Pentofixiline, Q10, TRT, L-Argenine, cialis
I have narrowing/dent/hinge on the left side of my shaft
My ED is getting worse
Had a PRP shot Aug 2021
I have a girlfriend
Age 46