pain improvement after xiaflex, is it possible?

[Jack1909]

Is there anyone in here experiencing some pain reduction after getting xiaflex shots onto the plaque? I got to the point I'm exploring any possible way to enhance my painful daily life.  

[wtrenton]

Yes. Absolutely. Unequivocally yes. I am largely pain-free at this point, having just this month finished my 10 rounds of Xiaflex injections.

Not saying everyone would see pain reduction -- I don't know, but I imagine every case is different. In my case, I had a moderate curve (30 degrees combined up/left), but I had severe pain EVERY time I was hard. Sex with my wife was miserable. It wasn't just a little pain, it was intense, constant pain when I was hard. So for me, eliminating that pain was my #1 goal by far. If I had to choose, I'd say it was far more important than the 30 deg. curve (although probably equally as important as stopping the curve from any further progression).

See my other post here for more background if it's helpful.
https://www.peyroniesforum.net/index.php/topic,17465.0.html

But for now, I'd say to talk to urologist. Xiaflex treatments absolutely can help reduce or eliminate the pain. I have none anymore, and there was a long, dark period where I didn't think that would be the case.